Podcasts about Akkermansia

In this episode, Dr. David Jockers is joined by his longtime friend Dr. Josh Axe, co-founder and chief visionary officer of Ancient Nutrition, founder of draxe.com, and founder of The Health Institute, for a deep dive into cellular longevity.   You will learn why some organs age faster than others, what's really happening inside your cell membranes and mitochondria as you get older, and which foods, from super berries and pomegranates to organ meats, healthy fats, fermented foods, and longevity mushrooms, do the most to slow that process down.   Dr. Axe and Dr. Jockers also break down his top longevity supplements, including vitamin D, soil-based probiotics, omega-3s, magnesium, and NAD/NMN, why quality matters so much more than quantity when it comes to supplements, and the surprising role of the gut microbiome, bee products, and daily herbal tea in living a longer, more vibrant life.   In This Episode:  00:00 Berry Powders Routine 00:14 Longevity Podcast Intro 04:02 What Is Cellular Longevity 04:52 Aging Organs and Cells 06:52 Cell Membranes and Mitochondria 09:26 Foods to Live Past 100 09:53 Super Berries for Longevity 13:18 Pomegranate and Urolithin A 17:24 Akkermansia and Ellagic Acid 19:00 Vegetables for Detox and Heart 20:35 Organ Meats and Methylation 23:44 Protein and Like Supports Like 25:37 Omega 3s and Healthy Fats 28:59 Oil Quality Over Smoke Point 29:18 Choosing High Polyphenol Olive Oil 30:19 Healthy Fats For Longevity 30:52 Fermented Foods And Gut Health 32:30 Longevity Mushrooms Explained 33:58 Longevity Foods Recap 34:42 Top Supplements Vitamin D 40:13 Probiotics Omega 3 And Quality 43:32 Avoiding Bad Supplements Calcium 44:21 NAD NMN And Supplement Impact 46:54 Magnesium Adaptogens And Green Tea 48:44 Bee Products And Venom Therapy 51:23 Herbal Tea Daily Ritual 52:28 Where To Find Dr Josh Axe 53:50 Final Thanks And Sign Off   This podcast is sponsored by Paleo Valley's Turmeric Complex, a whole-food organic turmeric formula (not just isolated curcumin) blended with coconut oil and black pepper for absorption, plus ginger, rosemary, and cloves for extra anti-inflammatory and brain-support benefits. Go to paleovalley.com/jockers for 15% off your order.   Bon Charge's Red Light Toothbrush combines the most researched red and near-infrared wavelengths (660 and 830 nanometers) with sonic power to support circulation, manage gingival inflammation, and aid recovery after dental procedures, all in your everyday brushing routine. It's HSA/FSA eligible, travel-ready, and low EMF. Go to boncharge.com and use code DRJOCKERS for 15% off, with free shipping and a 12-month warranty.   Inflammaging, the chronic low-grade inflammation that accelerates aging, often shows up first in the skin. Holistic Goddess Frankincense Castor Oil roll-on uses organic, cold-pressed, hexane-free castor oil and organic frankincense to deeply moisturize and soften the look of fine lines, with a cooling rose quartz applicator. Go to holisticgoddess.com and use code DRJOCKERS for free shipping.   Busy, stressed, low-carb, or training hard? You're likely losing more electrolytes than you realize. ReLyte from Redmond is made with Redmond's Real Salt, an ancient, unrefined Utah sea salt with trace minerals, plus two types of magnesium for better absorption, no sugar, and no artificial ingredients. Go to redmond.life/doctorjockers and use code JOCKERS for 15% off. "Pomegranates are right up there with goji berries as top superfoods for longevity."   Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean  TuneIn Radio   Resources:  Visit paleovalley.com/jockers to get 15% off Paleo Valley's Turmeric Complex and other products Visit boncharge.com and use code DRJOCKERS for 15% off the Red Light Toothbrush, with free shipping and a 12-month warranty Visit holisticgoddess.com and use code DRJOCKERS for free shipping on the Frankincense Castor Oil roll-on Visit redmond.life/doctorjockers and use code JOCKERS for 15% off ReLyte electrolytes     Connect with Dr. Josh Axe: Website – https://draxe.com/ Instagram – https://www.instagram.com/drjoshaxe/ Book – https://amzn.to/4glff4y   Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/

If your gut feels out of balance, where do you begin? In this episode, I'm breaking down some of my favorite cultured foods and beneficial microbes—from kefir and cultured vegetables to L. reuteri, S. boulardii, Bifidobacteria, HMOs, Akkermansia, and natto—and explaining how each one supports the gut in a different way. You don't need everything at once. The goal is to understand what your body may need, feed the right microbes, and slowly rebuild a healthier, more resilient microbiome. Episode link: https://www.culturedfoodlife.com/podcast/how-to-rebuild-your-gut-finding-the-fermented-food-your-body-needs-episode-371/ Link(s) I talked about: Article: https://www.culturedfoodlife.com/how-to-start-healing-your-gut-which-fermented-food-is-best-for-you/ Check out these other links: My Story Video: https://www.youtube.com/watch?v=CbX9Nv9OtGM For health tips and recipes, subscribe to our weekly emails. We'll also send you our free Getting Started Guide: http://bit.ly/2BnHpay Listen to all my podcasts: http://bit.ly/cflpodcast Become a Biotic Pro Member: http://bit.ly/2kkhwS1 Cultured Food Recipes: http://bit.ly/2UIfY2x Health and Food Topics: http://bit.ly/2SdzIOS My Amazon Shop: https://bit.ly/3KdhEge MY STARTER CULTURES Milk Kefir Grains: http://bit.ly/2rQ99PE L. Reuteri Superfood: https://bit.ly/LReuteriSuperfoodStarter L. Gasseri Superfood: https://bit.ly/LGasseriSuperfoodStarter Easy Kefir: http://bit.ly/2MQ1nPV Kefir Soda Starter: http://bit.ly/3YVErTa Kombucha Starter: http://bit.ly/2g2R9hE Vegetable Starter: http://bit.ly/2SzzVem Sourdough Starter: http://bit.ly/2IjaaXK Other items in my store: http://bit.ly/2HTKZ27 STAY CONNECTED Instagram: http://instagram.com/culturedfoodlife/ Facebook: https://www.facebook.com/CulturedFoodLife/ Pinterest: http://pinterest.com/donnaschwenk/ Twitter: https://twitter.com/donnaschwenk

“The microbiome world is moving from supplementation towards ecosystem restoration.” - Danielle ArnoldFor a long time, the functional medicine approach to gut health focused on getting rid of what shouldn't be there. It was all about finding the overgrowth, using antimicrobials, adding probiotics, and rebuilding. Those tools are still useful, but our understanding of the microbiome has become much more sophisticated. Now, we can think about restoring the gut's ecosystem, including the keystone species that help create an environment where beneficial bacteria can thrive, and opportunistic bacteria have a much harder time taking over.With the complex clients we see as women's health practitioners, this shift becomes especially important. Someone with endometriosis, histamine intolerance, MCAS, long COVID, metabolic dysfunction, or significant digestive symptoms may not be able to jump straight into eating 45 grams of fiber a day. Sometimes we have to work in a very specific order, supporting digestion, reducing overgrowth, rebuilding beneficial species, and then gradually giving those microbes the fibers and polyphenols they need. The goal is not simply a better stool test. It's a more resilient gut ecosystem that can better support the immune system, nervous system, hormone health, and the rest of the body.In today's episode, I'm joined by Dr. Oscar Coetzee and Danielle Arnold, CNS, from Designs for Health for a wonderfully nerdy conversation about what we now know about rebuilding the gut microbiome. We talk about new research on keystone species like Akkermansia, Faecalibacterium, and Roseburia, how these microbes work together, when antimicrobials may still be useful, why the order of treatment matters for sensitive clients, histamine and hormone health, H. pylori, digestive function, fiber and polyphenols, stool testing, how better gut microbiome support can become part of our clinical thinking, and more.Enjoy the episode, and let's innovate and integrate together!---Learn more or watch the video version of this conversation at https://integrativewomenshealthinstitute.com/how-to-rebuild-a-healthy-gut-microbiome-with-dr-oscar-coetzee-and-danielle-arnold/.Connect with me and access our entire platform at IntegrativeWomensHealthInstitute.com (https://integrativewomenshealthinstitute.com/).Find and follow us @integrativewomenshealth on YouTube (https://www.youtube.com/@integrativewomenshealth) and Instagram (https://www.instagram.com/integrativewomenshealth/).

In this episode of the Health Optimization Medicine Podcast, Boomer Anderson, Dr. Allen Bookatz, Dr. Ted Achacoso, and Dr. Jup Kuipers explore a misunderstood cause of chronic fatigue and leaky gut: the bioenergetic failure of your colonocytes. While many practitioners throw random probiotic strains and anti-inflammatory herbs at gut issues, metabolomic research shows this approach fails to address the root problem. The team explains how a starved microbiome forces gut cells to switch energy systems, leaking oxygen into the colon, destroying strict anaerobes, and allowing endotoxins to flood the bloodstream and drain your cellular vitality. From holobiont metabolomics to targeted mucosal protocols, this discussion reframes gut health through the lens of mitochondrial beta oxidation rather than simply managing inflammation.  Join us as we delve into: The Gut Hypoxia Trap: How starved colonocytes switch to anaerobic glycolysis and leak oxygen into the gut, killing off the strict anaerobes that make butyrate. The Endotoxemia Dilemma: How opportunistic bacteria pry apart tight junctions, allowing lipopolysaccharides (LPS) into the bloodstream and locking your cells into a permanent Cell Danger Response. Why Probiotics Fall Short: Why conventional protocols fail to repair the mucosal shield and how to properly signal Akkermansia muciniphila with complex polyphenols. The 4-Step Clinical Protocol: How to use stool metabolomics, pomegranate ellagitannins, oral tributyrin, and L-glutamine to rebuild the gut barrier from the ground up. Pathogenesis vs Salutogenesis: Why Health Optimization Medicine focuses on restoring root cause physiological health rather than perpetually suppressing symptoms. This episode is for you if: You are dealing with chronic fatigue, brain fog, and unyielding food intolerances despite taking probiotics. You want to understand the true biochemical mechanism behind leaky gut and systemic endotoxemia. You are a practitioner looking to replace guesswork with objective metabolomic testing and precision mucosal protocols. You can also find this episode on… YouTube: https://www.youtube.com/watch?v=_wZH8tJTFWw&feature=youtu.be Find more from Health Optimization Medicine and Practice (HOMeHOPe): Website: https://homehope.org/ Instagram: https://www.instagram.com/homehopeorg/ HOMeHOPe Conference 2026: https://homehope.org/homehope-conference-2026 Use PODCAST10 to get 10% OFF your purchase of the Clinical Metabolomics Module at https://homehope.org/products/clinical-metabolomics Find more from Troscriptions: Website: https://troscriptions.com/ Instagram: https://www.instagram.com/troscriptions/ Use POD10 to get 10% OFF your Troscriptions purchase at https://troscriptions.com/collections/our-products

This bonus content is a reading from Platypus, the CASTAC Blog. The full post by Megan MacGregor can be read at https://blog.castac.org/2026/08/microbiome-monitoring-smart-toilets-precision-medicine-and-the-post-genomic-bowel/. About the post: Imagine that every time you poop, your hygiene routine involves depositing your used toilet paper into a toilet-side receptacle. As you wash your hands, the device mixes, processes, and extracts microbial DNA from your stool. It sequences the microbial DNA for a real-time readout of your microbiome (the microbial genomes from within your gut, or at least the ones that made it to your stool), automatically sending the information to a large-scale microbiome database that integrates it into its data, algorithms, and analytic programs. The program connects to an app on your phone, telling you that based on your personal version of a healthy microbiome, today your microbiome is looking a little low in the bacterial species Akkermansia municiphila and high in some risky metabolites (the molecular outputs of some of your gut microbes).

Doctors officially renamed polycystic ovary syndrome (PCOS) to polyendocrine metabolic ovarian syndrome (PMOS) because the old name focused too narrowly on ovarian cysts while ignoring the condition's widespread metabolic and hormone disruption Researchers found that insulin resistance affects about 85% of women with PMOS, including many women with normal body weight, helping explain why symptoms like acne, irregular periods, facial hair growth, and weight gain often appear together The condition is associated with increased risk of serious long-term health problems, including Type 2 diabetes, fatty liver disease, high blood pressure, heart attack, and stroke, showing that PMOS extends far beyond reproductive health Gut dysfunction and chronic inflammation are linked to hormone imbalance in PMOS. Postbiotics from beneficial bacteria such as Akkermansia muciniphila may help strengthen the gut barrier, support insulin sensitivity, and calm inflammatory stress Daily movement, whole-food carbohydrates, stress reduction, sunlight exposure, and lowering exposure to seed oils and hormone-disrupting plastics may support metabolic health in women with PMOS

Barbara and Jacie are back, this time to share Jacie's personal health update while she deals with a CIRS relapse after moving into a new apartment. Jacie describes worsening histamine flares, a return of autoimmune symptoms like uveitis, and home testing that showed borderline endotoxins (100), and extremely high actinos (6 million). This prompted a small-particle cleaning and skin/environment retesting that suggested her boyfriend's microbes were contributing. While waiting to see CIRS clinician Dr. Andrea Jordheim, Jacie used an AIP diet, curcumin, astaxanthin, acupuncture, and a vibration plate to feel better. She reviews her extensive testing results (GI, infections, metabolomics, sinus, spike protein), her boyfriend's gut results (high Campylobacter, low Akkermansia), her dysbiotic gut findings and leaky-gut indicators, a very high spike protein result (23,000 vs 0.08), and next steps including fasting, nattokinase, quercetin, methylation and genetic testing. In her next update, she'll share MARCoNS and water testing (for uranium) results. For more information and support, join us at https://thecirsgroup.com TIMESTAMPS 00:00 Intro and disclaimer 01:06 Surprise puppy Story 02:20 Jacie's CIRS relapse 03:27 Histamine flares and uveitis 04:41 Home dust tests and skin tests to check for exposure 06:22 Feel better while waiting for your doctor: nutrition and supplements 07:44 Acupuncture and vibration plate 09:54 Doctor appointment and labwork 12:02 All the tests! 14:29 Working with Dr. Andrea Jordheim 15:55 Jacie's boyfriend's gut results 16:50 Jacie's GI dysbiosis findings 19:55 Spike protein test results and FLCCC protocol 22:17 Remaining tests 23:00 Concerning uranium levels in water 24:07 Minerals and methylation 26:16 Difficulty using carbs for fuel 29:06 Celiac genes, staying gluten free 31:46 High MPO may indicate endotoxins 33:05 Hormones, methylation, and hydration 34:38 Next testing, and supplements prioritized 36:10 The importance of collaborative care with your doctor 38:56 Wrap up For more information and support, join us at https://thecirsgroup.com LINKS MENTIONED IN THIS EPISODE: Work with Dr. Andrea Jordheim: https://mytransformationwellness.com/ Our interview with Dr. Lacey Venanzi: https://youtu.be/baldT8N7nl4?si=2HQ43ju_lV7PwC3w Celiac blood test: https://www.rupahealth.com/lab-tests/cyrex-array-3x Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet!  https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.  

Akkermansia muciniphila has been associated with improved metabolic markers and immune function in research, with studies exploring its role in obesity and Type 2 diabetes Research suggests Akkermansia may support intestinal barrier function, which has been studied in relation to inflammatory bowel disease and colorectal cancer risk Research has explored Akkermansia's relationship with the gut-brain axis and conditions such as anxiety and Alzheimer's disease, primarily in preclinical models Akkermansia has also been studied for its potential role in stress-related research Akkermansia supplementation has been studied in two forms (live and pasteurized) in published human trials. The pasteurized form was associated with greater improvements in metabolic markers in a small proof-of-concept study, though larger trials are needed

Most people think of the gut as a digestive organ. It is not. It is the upstream controller of your metabolism, immune function, brain health, skin, and hormones and almost everyone is running it on a depleted, misfed microbiome without knowing it.Dr. Colleen Cutcliffe, PhD is the co-founder and CEO of Pendulum Therapeutics, holds a PhD in biochemistry from Johns Hopkins, and spent over 15 years in pharma and biotech before pioneering next-generation probiotic science. Her team was the first in the world to manufacture Akkermansia, a strain found at high levels in virtually every centenarian population studied and depleted in almost every major chronic disease. What makes this conversation different from most gut health discussions is the level of scientific rigor behind it. This is not wellness theory. This is published research, clinical data, and a decade of actually building the science from the ground up.Join the most comprehensive *female-specific community for health and longevity optimization.* After over a decade dedicated to human performance and women's health, I created this space to share everything you need to know to optimize health and lifespan. Inside, you'll get access to exclusive protocols, live Q&As, the latest female longevity science, and a private, supportive community of like-minded women.https://kayla-barnes-lentz.circle.so/checkout/become-a-memberIn this conversation we explore:How your gut produces its own GLP-1 naturally and why synthetic versions may blunt that system over timeWhy Akkermansia is elevated in centenarians and depleted across virtually every chronic diseaseThe fiber gap: 95% of people are under-threshold and it is driving metabolic and colon health declineWhat early antibiotic use does to the microbiome and how to rebuild at any ageWhy soap may be fueling the allergy and asthma epidemic by stripping the skin's protective barrierHow butyrate links gut health, colon cancer risk, and natural GLP-1 productionWhy most probiotics on Amazon do not contain what the label claimsConnect with Kayla:Instagram: https://www.instagram.com/kaylabarnes/TikTok: https://www.tiktok.com/@femalelongevityTwitter:https://x.com/femalelongevityWebsite:https://www.kaylabarnes.com/Spotify: https://open.spotify.com/show/4OLWWn22RGB0argbRPvAaQ?si=8e91b3c9e0ce4054Apple: https://podcasts.apple.com/us/podcast/longevity-optimization-with-kayla-barnes-lentz/id1591130227Follow Her Female Protocol: https://www.protocol.kaylabarnes.comLearn more about Dr ColeenInstagram: https://www.instagram.com/drcolleencutcliffe/Pendulum Life Instagram: https://www.instagram.com/pendulumlifeco/Website: https://pendulumlife.com/

Naturopathic gastroenterologist Mark Davis, ND (FABNG), discusses his work in fecal microbiota transplantation (FMT), research, and integrative approaches to GI disease. Davis explains FMT history, screening criteria, delivery methods, how it differs from probiotics, and why it is highly effective for recurrent C. difficile (about a 90% durable cure), while noting FDA-approved products (Rebyota, Vowst) and off-label applications. He describes IRB-approved studies on naturopathic care for IBS and ulcerative colitis and a blinded project comparing consistency across 15–20 stool microbiome labs. The conversation covers evidence for diet in IBS/IBD (including SCD and a semi-vegetarian diet), low-FODMAP as a temporary tool, breath testing and relapse in SIBO, helminthic therapy options and legality, targeted probiotics (Saccharomyces boulardii, Akkermansia, soil-based species), enema therapies, indigo naturalis benefits and risks, saffron evidence for mood, telemedicine practice, and a crowdfunding platform for clinical trials.

The composition of your gut microbiome may have an encompassing influence on your health, including metabolic, neurological, and digestive function The diversity of your microbiome varies depending on your diet, age, location, and other factors. Age-related loss of diversity may be a meaningful contributor to age-related changes in function and the onset of chronic conditions In conventional antibiotic treatment, roughly 20% to 30% of Clostridium difficile cases recur after initial therapy, and severe or refractory cases carry meaningful mortality risk. Fecal microbiota transplant (FMT) has been reported in some trials to have cure rates around 80% to 90% Akkermansia muciniphila is among the gut bacteria most studied as a key contributor to microbiome health Reduced integrity of the mucin layer has been associated with what researchers describe as leaky gut syndrome. Akkermansia muciniphila is among the strains most closely studied for its interaction with the mucin layer

Today on Beating Cancer Daily, Saranne welcomes back Jacqui Bryan, a certified nutrition specialist and whole health educator, for an exploration of one of the latest breakthroughs in microbiome research: Akkermansia mucinophila. This episode uncovers why Akkermansia is being called the “hotshot” of gut bacteria and what makes it so vital, especially for those rebuilding gut health after cancer treatments like chemotherapy and radiation. Saranne shares her personal struggles with gut recovery as a Stage IV cancer survivor, while Jacqui explains how Akkermansia supports the gut lining, strengthens immunity, and influences everything from metabolic health to mood. With a mix of scientific insight and humor, they highlight practical, food-based strategies to naturally support Akkermansia, caution against unvetted supplements, and stress the importance of collaboration with your medical team.2025 People's Choice Podcast Awards Best Health Series FinalistRanked the Top 5 Best Cancer Podcasts by CancerCare News in 2024 & 2025,and #1 Rated Cancer Survivor Podcast by FeedSpot in 2024 to 2025. Beating Cancer Daily is listened to in 148 countries across 7 continents and features over 420+ original daily episodes hosted by Stage IV survivor Saranne Rothberg. To learn more about Host Saranne Rothberg and The ComedyCures Foundation:https://www.comedycures.org/ To write to Saranne or a guest:https://www.comedycures.org/contact-8 To record a message to Saranne or a guest:https://www.speakpipe.com/BCD_Comments_Suggestions To sign up for the free Health Builder Series live on Zoom with Saranne and Jacqui, go to The ComedyCures Foundation's homepage:https://www.comedycures.org/ Please support the creation of more original episodes of Beating Cancer Daily and other free ComedyCures Foundation programs with a tax-deductible contribution:http://bit.ly/ComedyCuresDonate THANK YOU! Please tell a friend whom we may help, and please support us with a beautiful review. Have a blessed day! Saranne

Fix Leaky Gut, Boost Testosterone & Slash Endotoxins with Spore-Based Probiotics | Kiran KrishnanYour bad gut bacteria might be the reason your testosterone, your immune system, and even your sperm count are struggling, and most probiotics never survive long enough to fix it. This episode reveals which strains actually make it through your stomach acid alive, and what happens once they do. Go To JustThriveHealth.com/asprey for a free 90 day supply of bitters with your next subscription. Host Dave Asprey sits down with research microbiologist Kiran Krishnan, co-founder of Microbiome Labs, the leading microbiome therapeutics brand among healthcare professionals. He has published multiple peer-reviewed studies, holds global patents, and has spent 20 years building companies focused on the science of the microbiome. His work centers on spore-based probiotics, the rare strains proven to survive the stomach's brutal acidity and actually rebuild the gut from the inside out. Kiran and Dave break down why 98 percent of conventional probiotics die before they ever reach your gut, and why spore-forming bacteria are different. They dig into the "gelding effect," the well-documented pathway where endotoxins from bad gut bacteria shut down testosterone production and drive up cortisol, and how fixing your microbiome can reverse it. They cover the connection between endotoxemia and nearly every major marker of aging, metabolism, and inflammation, why butyrate acts like a natural GLP-1 for fat loss, how Akkermansia can upregulate mitochondria and improve blood sugar control, and the surprising role vitamin K2 plays in bone density and functional medicine. This is biohacking at the cellular level, using ancient biology, fasting-adjacent metabolic pathways, and precision supplementation to optimize human performance from the gut up. You'll Learn: Why 98 percent of probiotics die in your stomach before they ever work What the "gelding effect" is and how gut bacteria can shut down testosterone How endotoxins drive inflammation, cortisol, and accelerated aging Why butyrate functions like a natural, low-cost alternative to GLP-1 drugs How Akkermansia improves mitochondrial function and blood sugar control The overlooked link between your microbiome and vitamin K2 production Why spore-based probiotics can survive gastric acid when most others cannot How 90 days of gut repair can measurably reduce circulating endotoxins Keywords: best probiotics that survive stomach acid, spore based probiotics benefits, gelding effect testosterone, endotoxins and testosterone, how to lower endotoxins, LPS gut bacteria, Akkermansia GLP-1 natural, gut bacteria and belly fat, vitamin K2 bone density, Kiran Krishnan microbiologist, Just Thrive probiotic, leaky gut symptoms, microbiome and testosterone, fecal transplant benefits, Dave Asprey, biohacking, longevity Resources: • Go To JustThriveHealth.com/asprey for a free 90 day supply of bitters with your next subscription • Learn More About All Of Just Thrive's Offerings At: https://justthrivehealth.com/ • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15? • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Thank you to our sponsors! - ZenBud | Dave's Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount. - BodyHealth | Visit BodyHealth.com and use code DAVE20 for 20% off your first purchase. - Redmond Real - Leaf Toothpaste | Go to https://redmond.com/asprey and use code ASPREY for 15% off your first order. - Show notes - ELITE Performance Coaching | If you'd like to discover where you may be addicted to struggle, allergic to success, and what may be standing between you and your next breakthrough, visit FastestChange.com Timestamps: 00:00 – Trailer 00:38 – Kiran Intro 02:01 – Stomach Acid & Probiotics 05:25 – Fauci & Spore Bacteria 13:58 – Losing Gut Diversity 19:01 – How Butyrate Is Made 22:11 – Dave's Personal Stack 24:00 – Quorum Sensing 31:26 – Endotoxins Explained 37:13 – Charcoal & Binders 39:41 – SIBO & Gut Bacteria 45:03 – Discovering Vitamin K2 49:33 – Gelding Effect & Testosterone 54:51 – Akkermansia & Weight Loss 01:02:17 – Role of Bitters 01:04:47 – Just Thrive Gift See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this episode of Vitality Radio, Jared breaks down the probiotic strains he trusts most and explains why not all probiotics deserve the same reputation. Learn the differences between spore-based probiotics, traditional human strains, postbiotics, and beneficial yeast, and discover how each supports digestive health, immune function, metabolism, mental health, gut barrier integrity, and overall wellness. Jared highlights the research behind favorite strains like Bacillus coagulans, Bacillus subtilis, Bacillus clausii, Lactobacillus reuteri, Akkermansia muciniphila, and Saccharomyces boulardii, while also explaining how he selected the ingredients used in Vital Spores, Back on Tract, and GLP-1 Metabolic Optimizer. Whether you're new to probiotics or looking to better understand the science behind today's most popular strains, this episode offers practical guidance to help you make more informed supplement decisions.Products:Back On TractPrecision Probiotic Vital SporesGLP-1 Metabolic OptimizerAdditional Information:448: VR Vintage: The Great Debate in Probiotics: Human Strains vs. Spores 627: GLP-1 Explained Part 1: How to Support Metabolism Without Drugs628: GLP-1 Explained Part 2: The Lifestyle Blueprint for Real Metabolic: OptimizationVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

Weight loss can feel like one of the biggest uphill battles for women with hypothyroidism and Hashimoto's. Even when you're eating well, exercising, sleeping, and taking thyroid medication, the scale doesn't always respond the way you'd expect. In this episode of Thyroid-Healthy Bites, I'm joined by functional nutrition and thyroid specialist Dr. Joni Labbe to explore what we can do beyond Ozempic to support healthy metabolism. We discuss emerging research on gut health, blood sugar, inflammation, and lifestyle factors that influence weight, while also keeping the conversation grounded in self-compassion and realistic expectations. In this episode, you'll learn about: Why weight loss is often more challenging with hypothyroidism and Hashimoto's What GLP-1 medications have taught us about appetite and metabolism The role of Akkermansia and butyrate in gut health Berberine and blood sugar support Saffron's emerging role in mood and metabolic health Hydrogen-rich water and where it may fit into metabolic health How sleep, stress, and nervous system regulation affect weight loss Foods and lifestyle habits that support metabolic health Functional medicine testing for stubborn weight loss resistance

On this episode, Jared explores one of the most important yet overlooked foundations of long-term health: intestinal barrier health, often referred to as "leaky gut." He explains what a healthy gut lining does, the lifestyle factors that may compromise it, and why supporting gut integrity can influence digestion, immune function, mood, and overall wellness. Jared also introduces Vitality Nutrition's new research-informed Leaky Gut Protocol, breaking down the role of ingredients such as L-glutamine, zinc L-carnosine, targeted probiotics, prebiotic fibers, and botanical compounds that help support a healthy intestinal lining and microbiome. If you've been looking for a practical, step-by-step approach to supporting digestive health naturally, this episode provides the science, the strategy, and the lifestyle principles to help you build a healthier gut from the inside out.Products:1 Month Leaky Gut Protocol Bundle3 Month Leaky Gut Protocol BundleCoreMend GINutraBio L-Glutamine PowderPrecision Probiotic Vital SporesSource Naturals GastricSoothe (Zinc L-Carnosine)Ancient Nutrition ColostrumRebuild+ Functional Beef Bone Broth ProteinION Gut SupportOmega-3Assimil-8 Digestive EnzymesAdditional Information:#427: How the Intelligence of Nature Can Help Restore your Gut Health with Kim StevensVisit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.This podcast is produced by DrTalks.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drtalks.com/podcast-service/⁠

Most people think saffron is just a spice, but when you look closely, it's a surprisingly complex botanical with a real problem in modern supplements: the compounds you can smell, and feel are often the first ones you lose during processing. We sit down with biochemist and Active Inside co-founder Benoit “Ben” Lemaire to unpack why safranal (the signature aromatic molecule) is volatile, why many extracts struggle to retain it, and how Safr'Inside uses a traditional adsorption and encapsulation approach to protect the raw material's original profile.We also get practical about what “standardised” should mean. Ben explains why older UV methods mainly measure colour and can misrepresent “safranal”, and why UHPLC testing changes the game for quality control, consistency, and even adulteration detection. From there we explore the clinical implications: chronic stress studies versus the need for acute stress support, and the proposed roles of safranal and crocins across serotonin and dopamine pathways.Then we widen the lens to the gut-brain axis and published microbiome work (including Akkermansia and indole metabolites), plus where saffron research is heading next, like vision support in type 2 diabetes. If you care about evidence-based herbal medicine, stress supplements, and what actually matters in manufacturing, this chat gives you a clearer framework to assess saffron products.If you found this useful, subscribe, share it with a colleague, and leave a review so more people can find the show. What question do you want us to tackle next?Shownotes and references are available on the Designs for Health websiteRegister as a Designs for Health Practitioner and discover quality practitioner- only supplements at www.designsforhealth.com.auFollow us on SocialsInstagram: DesignsforhealthausFacebook: DesignsforhealthausIXOM is the exclusive distribution partner for Activ'inside for ANZ. Please reach out to our team to learn more:Website - Activ'Inside : Your full service nutraceutical partnerLinkedin - ACTIV'INSIDE: Overview | LinkedInDISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your healthShownotes and references are available on the Designs for Health websiteRegister as a Designs for Health Practitioner and discover quality practitioner- only supplements at www.designsforhealth.com.auFollow us on SocialsInstagram: DesignsforhealthausFacebook: DesignsforhealthausDISCLAIMER: The Information provided in the Wellness by Designs podcast is for educational purposes only; the information presented is not intended to be used as medical advice; please seek the advice of a qualified healthcare professional if what you have heard here today raises questions or concerns relating to your health

Most people think gallbladder disease is all about gallstones. But what if the real story is hormones?In Part 2 of our Gallbladder Series, we take a deep dive into the fascinating relationship between estrogen, progesterone, menopause, the microbiome, and gallbladder function. We explore why women are significantly more likely to develop gallbladder disease, why perimenopause may be a perfect storm for biliary dysfunction, and how both high and low estrogen states can increase gallbladder risk.Along the way, we unpack the surprising idea that the gallbladder behaves like a hormone-responsive organ, discuss how oral contraceptives and hormone replacement therapy may influence gallbladder health, and explain why the microbiome may be one of the most overlooked pieces of the puzzle.Whether you're navigating perimenopause, supporting patients with digestive issues, or simply curious about the intersection of hormones and gut health, this episode offers a fresh perspective on a commonly overlooked organ.Why women develop gallbladder disease more often than menThe role of estrogen in bile production and gallbladder functionHow both estrogen excess and estrogen deficiency can increase gallbladder riskWhy perimenopause creates a unique challenge for gallbladder healthThe relationship between oral contraceptives, hormone therapy, and gallstonesHow progesterone influences gallbladder motilityThe estrogen–microbiome connectionChanges in the microbiome that occur during menopauseThe role of Lactobacillus, Bifidobacterium, Akkermansia, and other key organismsWhy menopause may increase the risk of biliary dysfunctionHow hormone fluctuations impact bile flow and gallbladder emptyingWhy oral estrogen carries different risks than transdermal estrogenClinical considerations for hormone replacement therapy in patients with gallbladder concernsThe importance of antioxidant protection for the biliary systemHow this information has changed the way we evaluate and treat patients✔ The gallbladder is highly responsive to hormonal signaling, particularly estrogen.✔ Both high and low estrogen states can negatively impact bile acid production and gallbladder function.✔ Perimenopause may be one of the highest-risk times for gallbladder dysfunction due to fluctuating hormone levels.✔ The microbiome and estrogen metabolism are deeply interconnected and may influence gallbladder health.✔ Menopause doesn't just affect reproductive hormones—it also changes the microbiome, bile metabolism, and digestive physiology.✔ The route of hormone therapy matters, especially for patients with a history of gallbladder disease.Part 3 of our Gallbladder Series: Practical treatment strategies, supplements, and clinical tools for supporting gallbladder health before and after gallbladder removal.In This Episode We Discuss:Key TakeawaysListen NextMusic provided by Blue Dot.

This episode is for ambitious, health-driven people who want to optimize their body from the inside out  and it makes the case that the most radical thing you can do for your brain, mood, and longevity isn't another nootropic or longevity supplement: it's fixing your gut. The science applies to anyone, but the framing throughout is high performers who feel "off" despite doing everything right.Did you know that over 90% of your serotonin, much of your dopamine and GABA, and the BDNF that builds your neurons are stimulated in your gut  and that a broken gut is, quite literally, a broken brain? In this episode, Andres sits down in person with Nathaly Marcus clinical nutritionist, functional-medicine pioneer, founder of the Bienesta functional medicine center, and author of Sano, salvaje y sabio (Healthy, Wild, and Wise)  for a deep, practical masterclass on the gut microbiome, postbiotics, and the nervous system underneath it all.Drawing on her own journey from three-and-a-half years of post-surgical pain, burnout, and "never enough" perfectionism to a philosophy of self-love, rituals over habits, and healing from gentleness instead of fear, Nathaly breaks down the 5 R's of functional medicine (starting with remove), why Akkermansia and butyrate are the quiet heroes of gut repair, and how postbiotics act as the "tools" your microbiome builds to talk to your brain, mitochondria, and hormones. She and Andres go deep on leaky gut and autoimmunity, SIBO and stress, the histamine surge more and more people are experiencing, and the longevity pathways FOXO, Klotho, Nrf2  you can switch on through epinutrients and smart discomfort.Key Topics Discussed:A Broken Gut Is a Broken Brain: Why the gut is the most important "agent of wisdom" in the body, and how inflammation there shows up as brain fog, anxiety, and low mood.Postbiotics Explained: The artisan-and-tools (and garden) metaphor why postbiotics, not just probiotics, are the molecules that rebuild your gut lining, mitochondria, and brain.Akkermansia & Butyrate: How this keystone bacteria feeds on mucin and polyphenols, why fasting lets the strongest species survive, and how butyrate lowers inflammation and lifts depression.Leaky Gut & Autoimmunity: The zonulin story, what a GI Map reveals (IgA, calprotectin, gluten antibodies), and why Nathaly argues most autoimmune disease Hashimoto's, lupus, psoriasis, even Parkinson's  begins in the gut.SIBO, Stress & Digestion: How survival mode lowers betaine and stomach acid, feeds bacterial overgrowth, and wrecks absorption  and why probiotics can sometimes make it worse.Histamine Intolerance: Why so many people are suddenly reacting to coffee, leftovers, and sulfur-rich foods, the role of the DAO enzyme, and the SIBO and food-diversity roots underneath it.Food Diversity Over Repetition: Why "marrying" one food every day drives sensitivities and inflammation, and how rotating protein, produce, and ferments restores biodiversity.Fiber as the Forgotten Pillar: Why half your plate should be fiber, how to build to ~30g a day without bloating, and the inulin, pectin, resistant starch, and green-juice tactics to get there.Longevity Pathways You Can Switch On: FOXO, Klotho, Nrf2, AMPK and sirtuins  and the epinutrients (rhodiola, curcumin, cacao, astaxanthin, sulforaphane, omega-3, PC) plus hormesis that activate them.Nervous System, Trauma & "I Am Enough": Why "I am safe and I am secure" is the foundational mantra, why motivation from fear leads to self-sabotage, and how rituals done from love not guilt become longevity.Actionable Tips:Start Your Day for Your Gut: Warm water with lemon and a little apple cider vinegar to stimulate digestive fire, then chia, flax, and a splash of olive oil to feed the gut lining a cleaner, lead-free alternative to psyllium.Rebuild Before You Add: Remove first (foods, toxins, disruptors, and toxic relationships), repair with glutamine, butyrate, and aloe, then reintroduce ferments slowly a "tequila shot" of rotating kefir, not a jar of sauerkraut.Feed Your Postbiotics: Prioritize polyphenols and prebiotics pomegranate, red/purple pigments, artichoke, asparagus, leek, onions, olive oil, and green tea to stimulate Akkermansia and butyrate.Make a Rotating Green Juice: Greens plus a detox herb (cilantro/coriander, parsley) and a daily-rotated polyphenol powder (pomegranate, maqui, açai) instead of overpriced all-in-one greens powders.Eat for Diversity, Not Efficiency: Rotate proteins, produce, seeds, and ferments through the week even "healthy" foods repeated daily can drive sensitivities and inflammation.Mind the State You Eat In: Be present, chew thoroughly, don't drink water with meals (sip between them), and drop into rest-and-digest first because how you eat changes how your body absorbs it.Do Hard Things on Purpose: Use temporary, intelligent discomfort sauna, cold, fasting, hard training to switch on FOXO, Klotho, Nrf2 and build a body that adapts to stress instead of breaking under it.Test, Don't Guess: Get a GI Map and food-sensitivity testing before assuming the problem is willpower or mindset find your personal bottlenecks first. 

Send us Fan MailRheumatoid arthritis is often thought of as a condition that only affects the joints, but emerging research suggests the story begins much earlier and extends far beyond them.In this episode of The Autoimmune RESET, registered nutritionist VJ Hamilton explores the latest evidence surrounding rheumatoid arthritis, including the fascinating links between the gut microbiome, intestinal barrier, oral health and immune regulation. You'll learn why researchers now believe that immune dysfunction may begin at mucosal surfaces such as the gut and mouth years before joint symptoms develop, and how factors including microbial diversity, nutrition, sleep and stress can influence immune resilience.VJ explains the science in an accessible and practical way, covering the role of key bacteria such as Prevotella copri and Akkermansia muciniphila, why butyrate-producing bacteria are so important, and how oral bacteria may contribute to immune activation. She also discusses the gut-joint axis, why stool testing has become such a valuable tool in personalised nutrition, and the simple lifestyle changes that can support your immune system alongside conventional medical care.Whether you've recently been diagnosed with rheumatoid arthritis, are supporting someone who has, or simply want to better understand autoimmune disease, this episode offers practical, evidence-based insights to help you look beyond symptom management and towards supporting the root causes of immune dysfunction.The Root Reset® IntensiveA private, in-person experience designed to help you connect the dots, identify potential root causes, and create a personalised six-month strategy for improving your health.The first Root Reset® Intensives will be taking place on Harley Street in London this summer.You can apply here. 

Welcome back to this week's Friday Review where I can't wait to share with you the best of the week!     I'm looking forward to reviewing:     New Natural Sunscreen (product review) Hormones Don't Tell the Whole Story (tip of the week) Akkermansia & Bone Loss (research) Inflammation & Aging (research)       For all the details tune into this week's Cabral Concept 3773 – Enjoy the show and let me know what you thought!   - - - For Everything Mentioned In Today's Show: StephenCabral.com/3773 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Akkermansia muciniphila is a gut microbe that thrives in your intestinal mucus layer. It's linked to improved metabolic health, but its levels decrease with age and poor diet Studies suggest Akkermansia may support a healthy weight by influencing fat mass, insulin sensitivity, and inflammatory markers, as shown in animal models. It also has roles in glucose and lipid metabolism Akkermansia may stimulate natural GLP-1 production. It may also help support blood sugar regulation and cardiovascular health markers Research has also linked Akkermansia levels to intestinal barrier integrity, immune regulation, and the gut microbial ecosystem, and has been observed as a marker associated with favorable metabolic profiles To boost Akkermansia levels, consume polyphenol-rich foods and high-inulin vegetables. Supplements are available but require careful dosing and timing for effectiveness

Bakterien können krank machen – aber sie können uns offenbar auch dabei helfen, gesund zu bleiben. In dieser Folge sprechen wir über ein besonderes Darmbakterium mit kompliziertem Namen und erstaunlicher Wirkung: Akkermansia muciniphila. Eine neue Studie deutet darauf hin, dass diese Bakterien dabei helfen könnten, das Gewicht nach einer Diät besser zu halten.In dieser Folge geht es um Genuss, den Jojo-Effekt und die Frage, ob wir uns alle bald Bakterien kaufen sollten.00:59 Akkermansia muciniphila04:37 Tote Keime11:22 Interessenkonflikt14:18 Bakterien im Selbstversuch?

In this Mini Motivation episode, host Amelia Phillips is back with the Microbiome Doctor, gastroenterologist Dr Paul Froomes, to find out how we can all master our gut microbiomes. Amelia asks about 'weeding and seeding', the best probiotics, and the potential of Akkermansia to support metabolic health and weight management. Plus, Dr Paul gives his go-to pre- and probiotics for a healthy, happy, balanced gut. About the guest: Dr Paul Froomes is a Melbourne-based gastroenterologist with over 30 years of experience helping patients with complex gastrointestinal disorders. Trained at Monash University and the Royal Australian College of Physicians, he has gone on to complete advanced training in endoscopy and oesophageal physiology, as well as a master’s degree in liver disease at the University of Melbourne. Beyond his hospital and clinic work, Dr Froomes has dedicated his career to finding the root causes of gut issues like IBS, reflux, and inflammatory bowel disease – publishing research, training doctors, and now building innovative treatment programs that are changing lives. Dr Froomes is the co-founder of The Microbiome Clinic™, a new age medical practice built to make his decades of learnings about the microbiome accessible to more patients and practitioners. After seeing countless people struggle with conditions that didn’t improve under standard care, he recognised the need for a model that treats the root cause – imbalances in the microbiome – rather than just the symptoms.Follow Dr Paul on Instagram: https://www.instagram.com/drpaulfroomes/ The Microbiome Clinic: https://themicrobiomeclinic.com.au/ About the host: Amelia Phillips is an exercise scientist, nutritionist, and published researcher (BSc, MNut) with a career spanning 26 years in health. A respected media presenter, Amelia has been featured on Channel 9’s hit show Do You Want to Live Forever? and is dedicated to helping people build a life of energy, connection, and purpose at any age or stage of life.Instagram: @_amelia_phillipsHave a question? Email: ap@ameliaphillips.com.auFind out more at: www.ameliaphillips.com.au CREDITSHost: Amelia Phillips Guest: Dr Paul Froomes Audio Producer: Darren RothMusic: Matt Nicholich Production Partner: Nova Entertainment Pty Ltd Healthy Her acknowledges the Traditional Owners of the Land we have recorded this podcast on, the Gadigal people of the Eora Nation. We pay our respects to their Elders past and present and extend that respect to all Aboriginal and Torres Strait Islander cultures. See omnystudio.com/listener for privacy informationSee omnystudio.com/listener for privacy information.

I am happy to connect with Dr. William Li today! He is a world-renowned physician, scientist, speaker, and author. He is known for leading the Angiogenesis Foundation, and his groundbreaking work has impacted more than 70 diseases. He is also a Ted-X speaker and the author of Eat to Beat Your Diet, one of my favorite books thus far this year.  Dr. Li's latest book is about what happens in the body, how it should operate, and the steps we can take to restore it to its hard-wired state. We dive into how body fat impacts our health, the role of metabolism throughout our lifetime, the differences between the three fat-impacting hormones, including leptin, adiponectin, and resistin, and gender differences. We speak about new drugs like Ozempic and Semaglutide, the role of brown fat, the impact of the microbiome and specific bacteria, and nutrition and lifestyle. IN THIS EPISODE YOU WILL LEARN: Why Dr. Li chose this time to write his latest book  Is 60 the new 20? The four stages of metabolism hardwired into each of us  How excess body fat derails metabolism, and how can we unleash our inner metabolism Why is it better to eat slowly? Why should we learn to respect and tame our fat instead of hating or fearing it? Dr. Li shares his views on new prescription drugs like Ozempic and Semaglutide. Interesting facts about body fat Changes that occur in our body fat distribution as we get older How can we help our bodies fight excess body fat, bring our inner metabolism to the surface, and reduce inflammation by being aware and mindful? Modern-day lifestyle choices and metabolic disease Dr. Li discusses the interplay between the gut microbiome and metabolism, as well as the role of Akkermansia.  Some everyday foods contain natural chemicals that can activate our body's defenses, tame metabolism, and fight body fat. BIO William W. Li, MD, is an internationally renowned physician, scientist, and New York Times bestselling author of the forthcoming book “Eat to Beat Your Diet: Burn Fat, Heal Your Metabolism, Live Longer”. His groundbreaking work has led to the development of more than 30 new medical treatments and impacts care for more than 70 diseases, including cancer, diabetes, blindness, heart disease, and obesity. His TED Talk, “Can We Eat to Starve Cancer?” has garnered more than 11 million views. Dr. Li has appeared on Good Morning America, CNN, CNBC, LIVE with Kelly and Ryan, and the Rachael Ray Show, and he has been featured in USA Today, Time Magazine, The Atlantic, and O Magazine. He is the president and medical director of the Angiogenesis Foundation. Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. William Li On his⁠ website⁠ Social media: @DrWilliamLi Dr. William Li's latest book, ⁠Eat to Beat Your Diet: Burn Fat, Heal Your Metabolism, and Live Longer⁠ is available from most bookstores.

In this episode, Tara dives into one of the most important — and often overlooked — players in metabolic and gut health: Akkermansia muciniphila. She explains how this keystone bacteria influences weight regulation, inflammation, blood sugar balance, and gut integrity, and why both low and elevated levels can signal deeper issues in the body. Tara also breaks down the common misconceptions around weight loss, the role of the microbiome in supporting metabolic health, and why diet alone is often not enough to optimize gut function. You'll learn practical strategies to support Akkermansia naturally, when supplementation may or may not be helpful, and why proper testing is essential for understanding your unique gut environment. We cover: What Akkermansia is and why it's considered a "keystone" bacteria How it influences weight, metabolism, and inflammation Why both low and high levels can be a problem The truth about Akkermansia supplements (and why I don't rely on them) The exact foods and strategies that support healthy levels Why gut testing is essential if you actually want answers   Attend My Brand New Masterclass on May 7th at 8pm EST / 5pm PST! The Gut Fix Masterclass: Stop Blaming Food! The Real Reason You've Still Got Bloating and Pooping Problems & How to Fix Your Gut for Good Save Your Spot HERE

There's one gut bacterium getting a lot of attention in the research world—and for good reason.In this episode, we're diving into Akkermansia muciniphila, a key microbe that plays a major role in gut lining integrity, metabolic health, and overall inflammation balance. Often referred to as a “beneficial” bacteria, Akkermansia has been linked to improved insulin sensitivity, weight regulation, and a stronger gut barrier.Pendulum Labs Akkermansia linked in my fullscript 15% offFollow me on socials @drhalieschoff

Hosts: Ed Jones (Owner – Nutrition World) & Clint Powell A variety of topics all related to living a healthy life Presented by: Nutrition World www.nutritionw.com Broadcasting from the Nooga Dentistry Studio www.noogadentistry.com Production of: Whitfield Media Group www.vitalhealthradio.com Title: All About Peptides, & The Good, Bad & Ugly of GLP-1's [0:00:00]  Ed's Restaurant Story & Healthy Eating Choices Ed's recurring bit: “Where did Ed eat this week?” Long‑time favorite restaurant Epicurean. Discussion of consistent healthy ordering and making good choices at long‑standing, family‑owned restaurants. [0:03:13]  Building a Health “Team” & Ed's Top Learning Resources Tease of today's main topic: peptides with local expert Noel Lawson, NP. Ed stresses “team approach” to aging—no single practitioner has all the answers. Learners vs. non‑learners: why ongoing self‑education is critical for health. Ed's 4 favorite online resources: Mercola.com – more cutting‑edge, sometimes controversial content. DrJockers.com – accessible, visual education on ailments and nutrients. GreenMedInfo.com – indexed medical literature backing natural claims. Nutrition World Instagram – short, practical health “snippets”. Story: Nutrition World wins a surprise $10,000 award from Ancient Nutrition for #1 sales growth in the U.S., tied to belief in product quality. [0:10:38] Introducing Noel Lawson & “What Are Peptides?” Introduction of Noel Lawson, NP (Double Bridges Health & Wellness), now practicing on the Nutrition World campus. Noel's background: Transition from traditional medicine to functional medicine due to patient frustration, worsening chronic illness, and provider burnout. Goal: more prevention and root‑cause care. Orthopedic background led her to peptides. What is a peptide? Peptides are like the body's Morse code—specific chains of amino acids acting as signals. Under ~40 amino acids = peptide; longer chains = protein. Body breaks down dietary protein into amino acids and re‑assembles them into peptides as needed (e.g., for repair). As we age, the body produces fewer peptides, which is why we heal slower and are more prone to injury and inflammation. [0:19:26] Functional Medicine + Peptides: Approach, Expectations & Use Noel's approach: Combines functional medicine with peptides. Peptides only work well if the materials (sleep, nutrients, stress management, movement) are in place. Uses comprehensive labs to optimize baseline health first. Delivery & protocols: ~90% of peptides are injectable (tiny insulin‑type needle, usually daily). Some oral options exist Local injections near the injury area Expectations & timelines First 2–3 weeks: less inflammation, modest improvement in pain, sleep, and energy. 6–8 weeks: improved range of motion and strength. After 3 months: realistic minimum for true tissue change; peptides can't shortcut normal cell‑turnover timelines. [0:21:41] Specific Peptides & Treatment Logistics High‑demand musculoskeletal peptides: BPC‑157 and TB‑500: commonly used for tendons, ligaments, muscle and injury recovery. Growth hormone related peptides: Examples: samorelin, CJC, ipamorelin, tesamorelin. Stimulate the pituitary to release natural human growth hormone (HGH) rather than supplying exogenous HGH. Potential benefits: lean muscle mass, better body composition, cardiometabolic support. Monitored via IGF‑1 levels to avoid excess. PT‑141 for sexual health: Crosses the blood–brain barrier and activates pleasure/desire centers. Can cause nausea in some people; alternative forms (nasal spray, sublingual troche) may reduce side effects. How Noel works with patients: Website: doublebridgeswellness.com Contact form → email → optional free 20‑minute expectations call to see if there's a good fit. 1‑hour new patient visits, not rushed; she practices on the Nutrition World campus. [0:35:01] GLP‑1 Drugs (Ozempic, Trulicity, Mounjaro): Good, Bad & Ugly Case study: 65‑year‑old woman with pre‑existing gastroparesis put on Trulicity. Developed severe vomiting, dehydration, abdominal pain; was initially reassured to “get used to it.” Second dose led to life‑threatening pancreatitis, requiring hospitalization. Later prescribed Mounjaro by same clinic despite this history. The “Good” of GLP‑1s: In Curt's clinic, used selectively for: Poorly controlled diabetes (A1c > 10, average sugars in the 300s). Significant obesity. Can lower blood sugar and drive weight loss, by suppressing appetite The “Bad”: Common GI side effects (up to ~50% of users): Nausea, vomiting, constipation. Worsening gastroparesis (slow gut motility). Rapid weight loss often includes loss of muscle and bone, not just fat—hurts longevity and functional strength. Ozempic face: gaunt facial appearance from aggressive fat/muscle loss. Risk of hypoglycemia Visual issues, including increased macular degeneration risk. Psychiatric concerns: Emerging data on increased suicidal ideation, especially notable because trials excluded psychiatric patients. The “Ugly”: Pancreatitis, gallbladder problems. Thyroid tumors in some models. Possible cardiac atrophy. Massive growth in use: tens of millions prescribed, with many discontinuing within a year due to side effects or cost. Risk that people treat GLP‑1s as a “magic bullet” without nutrition or lifestyle change—and regain ~85% of lost weight after stopping. Curt's conclusion: GLP‑1s should be reserved for specific, high‑risk cases and paired with close coaching. For most people, there are safer, natural options. [0:50:12] “Nature's Ozempic,” Gut Health & Upcoming Events Ed and Curt on supporting GLP‑1 pathways naturally: Berberine – “nature's Ozempic” for blood sugar and metabolic support. Akkermansia (probiotic strain) – gut health, metabolic benefits, GLP‑1 stimulation. Butyrate – short‑chain fatty acid that: Supports gut lining / leaky gut repair. Improves colon health and may help increase GLP‑1. Ed reports best bowel function of his life using 2 caps/day. People who start GLP‑1s often increase supplement use, but tend to stop supplements when the drug stops. Coaching is needed so they maintain nutrition and supplementation after GLP‑1 discontinuation. Practical tips & announcements: Colonoscopies: clear protein drinks are now typically allowed on prep day—can help preserve muscle and stabilize blood sugar. Upcoming Lunch & Learn (online): Topic: “The Microbiome's Impact on Longevity”. Format: Instagram Live (@NutritionWorld), Tuesday, May 5 at 12:15 PM. Upcoming in‑person lecture at Nutrition World campus: Topic: “Taming the Yeast: Candida‑Reducing Strategies”. Thursday, May 21 at 5:30 PM. Registration via nutritionw.com → Events. Closing: Ed and Clint wrap up, reiterating their mission of clear, actionable health guidance and noting the show will be out on major podcast platforms. The post Radio Show / Podcast – May 3, 2026 first appeared on Vital Health Radio.

Sleep and weight gain are directly connected. Poor sleep disrupts hormones, raises blood sugar, tanks testosterone and estrogen, causes fatty liver, and wrecks your gut. If you've been doing everything right and the scale won't move, your sleep could be the missing link. FEATURED PRODUCT Chill by MSW Nutrition is a powdered drink mix formulated to support your body's natural calming chemistry — exactly what's needed when chronic stress and cortisol overload are stealing your sleep. Featuring GABA, L-Theanine, myo-Inositol, Taurine, and Magnesium, Chill helps balance neurotransmitters, quiet the nervous system, and promote the deep, restorative sleep your hormones, metabolism, and weight depend on — all five mechanisms discussed in this episode.

Metabolism gets oversimplified all the time. Eat less, move more. That's the whole conversation. For a lot of people, that's where medical gaslighting begins. In this solo episode, I wanted to slow down and actually explain what metabolism is: your body's system for managing energy. Not a measure of effort or discipline, actually a biological process influenced by multiple factors at once. I walk through four of the most important ones: food quality, insulin signaling, the microbiome, and mitochondrial function. I also get into why the "calories in, calories out" model doesn't account for how differently your body processes various foods, and why nutrigenomics, the study of how food communicates with your genes, changes the way we should be thinking about nutrition entirely. We also talk about Akkermansia, a gut bacterium that's showing up more and more in metabolism research, and the role of polyphenol-rich foods in supporting it. The episode closes with a practical checklist you can actually use: healthy fats, eating a wide variety of colorful plants, reducing refined sugar and flour, incorporating intentional movement, targeted nutrients, and consistent sleep. The goal of this conversation is less blame, more clarity. Fewer generalizations that leave people feeling stuck or at fault for something that has a real biological explanation. Want more practical health tips? Join my newsletter! https://freechapter.lpages.co/newsletter-opt-in/ Check us out on social media: https://www.instagram.com/drefratlamandre https://www.facebook.com/drefratlamandre https://www.tiktok.com/@drefratlamandre #functionalmedicine #drefratlamandre #medicaldisruptor  #NPwithaPHD #nursepractitioner #medicalgaslighting Chapters 00:00 Introduction 01:30 What Metabolism Actually Is 03:30 Why Calories In/Out Doesn't Work 05:30 Food Quality as Information 08:00 Insulin, Microbiome & Mitochondria 12:00 What To Actually Do 14:30 Closing Thoughts Learn more about your ad choices. Visit megaphone.fm/adchoices

Send us Fan MailYour supplement shelf can turn into a silent monthly subscription, and the scariest part is not the cost. It's the uncertainty. We sit down to unpack why supplements so often feel like a black box, how isolated nutrients can behave differently than nutrients in whole foods, and what a sensible, evidence-based supplement routine looks like when you care about real outcomes like strength, metabolic health, energy, and long-term resilience. We walk through the decision filters we use as clinicians, starting with the most straightforward case: measured deficiencies you can actually track, like vitamin B12 or vitamin D. From there, we share John's “Four I's” checklist (imbalance, insufficiency, infection, isolation) and why the food matrix matters so much when you're deciding between a capsule and a plate. We also get specific about common scenarios, including vegan and plant-based nutrient gaps (especially zinc and B12), aging and fatty acid needs, and why omega-3 fish oil studies can look mixed compared with the consistent benefits of eating oily fish. We dig into risks that don't get enough airtime, including supplement overload, vitamin toxicosis concerns, and medication-driven nutrient depletion. Metformin and B12, statins and CoQ10, and proton pump inhibitors and mineral absorption all come up, along with a bigger theme: changing a biomarker is not the same as improving an outcome. To keep things grounded, we share what we actually take right now, why creatine has one of the strongest evidence bases in sports nutrition and healthy aging, how creatinine lab values can be misread, and where berberine and targeted probiotics like Akkermansia may fit for metabolic health when paired with lifestyle changes. We close with practical tips on supplement quality and third-party testing, plus how to build a short-term “bridge” plan with clear stop rules. Subscribe for more evidence-based self-care, share this with someone whose cabinet is overflowing, and if you found this helpful, leave a review and tell us what supplement you want us to break down next. For video recording and open source reference articles: www.thehealthedgepodcast.com

You've heard that probiotics are important — but do you actually know what to take, why it matters, and whether what you're buying is doing anything at all? In this episode, Dr. Terri sits down with Elizabeth for a no-fluff breakdown of everything probiotics: what they are, why modern life is depleting them, and why strain specificity is the future of gut health. They cover the surprising reason you might be too clean for your own good, why rotating your probiotics matters more than chasing the highest CFU count, and how the gut microbiome connects to weight management, hormone health, insulin resistance, depression, cardiovascular disease, and more. You'll also hear how two targeted EVEXIAS formulations — the EVEXIAS GL Pro and the vaginal/bladder-specific probiotic — were designed with clinical research behind them, and why Akkermansia muciniphila may be the most depleted and most important strain in the American gut. Plus: the case for GI mapping, what conventional GI doctors are missing, and why the Japanese eating raw fish into their 100s might have something to teach us about the standard American diet. If you or someone you love is dealing with chronic inflammation, recurring infections, weight struggles, or GI issues — this episode is a must-listen. In This Episode You'll Learn: What probiotics and prebiotics actually are — and why you likely need them even if you eat well The modern lifestyle factors quietly decimating your gut microbiome (including one you'd never expect) Why taking the same probiotic for years may be doing you less good than you think How gut dysbiosis drives hormone imbalances, insulin resistance, depression, cardiovascular disease, and more What makes next-gen, strain-specific probiotics different — and the clinical research behind EVEXIAS GL Pro How the vaginal and bladder microbiomes connect to gut health, and why chronic infections often start in the gut When and why GI mapping is worth it — and what conventional gastroenterology is missing Episode Chapters: 00:02:55 – Probiotics 101: What They Are and Why the American Gut Is in Trouble 00:07:54 – The Hidden Causes of Gut Depletion: Over-Sanitation, Glyphosate, and Modern Diet 00:11:45 – Dysbiosis as the Root Cause: From Hormones and Insulin Resistance to Heart Disease 00:17:59 – Strain Specificity and Next-Gen Probiotics: Why Diversity and Rotation Matter 00:22:01 – Targeted Formulas: The Vaginal Microbiome, EVEXIAS GL Pro, and the Case for GI Mapping Helpful Links: GLPRO Fact Sheet Need Probiotics? Find an EVEXIAS provider near you Here Learn more about your ad choices. Visit megaphone.fm/adchoices

Why do so many women suddenly experience mysterious bloating, weight-loss resistance, and severe brain fog the moment they hit midlife? In this timely episode of Beauty Bytes, I am joined by Cynthia Thurlow, a nurse practitioner, host of the Everyday Wellness podcast, and author of the highly anticipated new book, The Menopause Gut . We dive deep into a conversation that the medical community has ignored for far too long: the critical connection between declining estrogen and your microbiome . Cynthia explains the concept of the "estrobolome" and reveals how the loss of estrogen literally breaks down the mortar of your intestinal walls, causing leaky gut, new food sensitivities, and systemic inflammation . We explore why treating midlife mood changes might actually start in the digestive tract, considering 70 to 80% of our neurotransmitters are produced in the gut. Cynthia also breaks down the harsh reality of midlife insulin resistance and sarcopenia, while giving us the exact blueprint for reversing it—from tracking macros to hit 100 grams of protein, to slowly building up to 25-30 grams of fiber to stimulate your body's natural GLP-1 production . We even tackle the taboo topic of why you must be pooping every single day to eliminate excess estrogen . If you are tired of being told that midlife weight gain and exhaustion are "just normal," this episode is your ultimate guide to taking your power back.Guest Information:Cynthia Thurlow is a nurse practitioner, international speaker, and host of the Everyday Wellness podcast. Her new book, The Menopause Gut, is available for pre-sale and officially launches on April 28. You can learn more and access her pre-sale bonuses at cynthiathurlow.com or follow her on Instagram

RNA microbiome testing reveals what DNA gut tests fundamentally miss. Your gut bacteria have 3,000+ genes each — DNA tests see zero of their actual activity. Dr. Momchilo (Momo) Vuyisich, Co-founder & CSO of Viome and former Los Alamos National Laboratory scientist, explains why RNA-based metatranscriptomics is a quantum leap over DNA sequencing for understanding your microbiome and personalizing nutrition. Meet our guest Dr. Momo Vuyisich spent 12 years at Los Alamos National Laboratory developing RNA-based technology for digitizing human biology. He co-founded Viome in 2016 with Naveen Jain, and the platform has since tested 500,000+ customers across 100+ countries. His personal journey with NEU5GC autoimmune sensitivity drove his mission to replace opinion-based nutrition with data-driven, personalized recommendations. Thank you to our partners Outliyr Biohacker's Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Ultimate Health Optimization Deals: a database of of all the current best biohacking deals on technology, supplements, systems and more Latest Summits, Conferences, Masterclasses, and Health Optimization Events: join me at the top events around the world FREE Outliyr Nootropics Mini-Course: gain mental clarity, energy, motivation, and focus Key takeaways DNA microbiome tests show composition only — RNA tests reveal which of 3,000+ bacterial genes are actually active 16S rRNA sequencing cannot distinguish pathogenic bacteria from beneficial ones Akkermansia can protect or destroy your gut lining depending on fiber intake and gene expression Carnitine supplements may cause cardiovascular disease via the TMAO pathway in certain people Viome's biological aging clock shows keto and paleo dieters age faster on average No whole food is universally good or bad — personalization requires your own molecular data The gut microbiome stays stable for 5-6 months; test semi-annually Viome currently measures 25,000 of ~100,000 biochemical reactions powering the body Three randomized controlled trials validate Viome's personalized nutrition approach   Episode highlights 00:00 Introduction 02:44 Why RNA is the single best molecule to study 06:16 RNA instability — why it took 6 years to develop 08:02 Why 16S sequencing is nearly useless 11:02 Akkermansia's 3,000 genes: help or harm? 17:37 Microbiome as a dynamic self-adjusting ecosystem 23:20 NEU5GC sensitivity & mammalian food reactions 25:50 Food sensitivities (IgG) vs allergies (IgE) 29:55 Viome's 3-part approach: seal gut, reduce inflammation, personalize 41:07 Biological aging clock: keto & paleo age faster 49:13 Dry fasting crashed mitochondrial function score 52:07 Machine learning identifies metabolic bottlenecks 1:00:23 Viome measures 25% of human biology, 10% actionable   Links Watch it on YouTube: https://youtu.be/bB8Zj_9pIv8  Full episode show notes: https://outliyr.com/257  Connect with Nick on social media Instagram Twitter (X) YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What if everything you've been told about your metabolism is missing the most important piece? In this episode, I sit down with Dr. Colleen Cutcliffe to uncover the powerful and often overlooked connection between your gut microbiome, your hormones, and your metabolism. We dive into why so many women start experiencing stubborn weight changes, cravings, energy crashes, and insulin resistance, especially in perimenopause and menopause, and how the root cause may go far deeper than calories or willpower. I also ask the big questions you've probably wondered about but never had answered clearly. Is your gut actually acting like an endocrine organ? Why are most probiotics not created equal? And what is this “Akkermansia” strain everyone is starting to talk about and why does it matter so much for metabolism, GLP-1 signaling, and even longevity? We break down the science in a way that actually makes sense and connect it back to what's happening in your body right now so you can finally see the full picture. Topics We Cover in This Episode:  Why your metabolism may feel completely different lately and what's really driving it The hidden role your gut plays in hormone signaling and insulin response What most probiotics are missing and why that matters more than you think The surprising reason some people struggle with cravings, fullness, and energy How your microbiome shifts during perimenopause and menopause The connection between gut health, inflammation, and long-term disease risk Why “you are what you eat” is only part of the story What might actually be influencing longevity at the microbial level Share this episode with a friend who's been struggling with the same symptoms, and make sure you're subscribed! Resources & Links Connect with Dr. Colleen Cutcliffe

Your gut is home to trillions of bacteria that help digest food, train your immune system, and quietly influence how healthy you feel day to day, when that system gets out of balance, problems can show up far beyond digestion. We'll break down what damages the gut, what actually helps restore it through everyday habits like food choices, movement, and sleep, and clear up the confusion around fecal microbiota transplantation, including what it is and what it isn't. Finally, we'll connect the dots between gut health and brain health, explaining how your microbiome shapes mood, focus, and long-term health in ways most people never realize.   Key Takeaways To Tune In For:(04:16) – The Interconnected Gut Microbiome (09:59) – Dysbiosis and Gut Migration (14:30) – Stomach Acid and Migrating Motor Complex (19:59) – Akkermansia and Probiotic Limitations (26:06) – Diet Sleep and Stress for Gut Health (33:38) – The Power of Fecal Microbiota Transplant   Resources talked about in this episode:Websites: www.novelbiome.com    Social media handles: FB IG X YouTube

Are your daily probiotics actually healing your gut, or are they just passing straight through your system? In this fascinating episode of Beauty Bytes, I am joined by clinical nutritionist Oscar Coetzee to discuss the massive paradigm shift happening in longevity medicine: cultivating powerful "Keystone" bacteria.Oscar explains why standard probiotics are like buying a bouquet of "cut flowers" that inevitably wilt, and introduces the revolutionary science behind anaerobic strains that actually plant themselves into your gut lining. We dive into the incredible benefits of Akkermansia, a bacteria that triggers your body's natural GLP-1 production, and uncover a specific microbe that produces endogenous salicylic acid to clear acne and rosacea from the inside out.If you want to understand the true gut-skin connection, this is a must-listen.

Host: Unique DoctorGuest: Dr. Jason Hawrelak (Microbiome Specialist & Educator)Episode SummaryIn this episode, Unique Doctor sits down with renowned clinician and researcher Dr. Jason Hawrelak to discuss why the modern trend of "carpet-bombing" the gut with antimicrobials like Berberine and Oregano oil may be doing more harm than good. They explore the nuances of Akkermansia, the dangers of hidden chemicals in natural supplements, and how to use fiber and targeted herbs as "snipers" to restore a healthy internal ecosystem.Key Information & HighlightsThe Problem with "Natural" Antimicrobials: Many popular herbal treatments (Berberine, Oregano Oil, Grapefruit Seed Extract) are non-selective. They kill beneficial Bifidobacteria and butyrate-producers, often leading to a "bloom" of pathogens like E. coli and Klebsiella shortly after treatment.The "Sniper" Herb – Pomegranate Husk: Unlike broad-spectrum killers, Pomegranate Husk acts selectively. It inhibits pathogens and fungi while actually encouraging the growth of beneficial microbes.The Oxygen/pH Dynamic: You can suppress pathogens without "killing" them by changing the environment. Pathogens hate acidity and oxygen-free environments. Feeding your gut fiber creates Butyrate, which sucks oxygen out of the gut and lowers the pH to a level pathogens cannot tolerate.Akkermansia Insights: If you are missing Akkermansia muciniphila, current supplements may not "colonize" you permanently. However, red polyphenols (Pomegranate, Dragon Fruit, Cranberry) and prebiotics like Inulin can drastically increase levels if the species is still present.The Probiotic Myth: Probiotics rarely "recolonize" a healthy gut. They are transient travelers that perform specific tasks (e.g., speeding up transit time or producing GABA for anxiety) but usually don't stay forever.Recommended ResourcesThe Corn/Quinoa Test: Eat corn or black quinoa and track how many hours/days it takes to appear in the stool (Optimal is 18–30 hours).Microbiome Testing: Look for Shotgun Metagenomics or 16S DNA testing rather than basic PCR pathogen tests. I like Tiny Health for North America. Code: youregreatDietary Goals: Aim for 40–50g of fiber daily from diverse plant sources.Watch the episode here: https://www.youtube.com/@beanprotocolJoin The Legume Love letter Newsletter here: LOVE LETTERS

Microbiome scientist Colleen Cutcliffe joins Jeff to discuss how gut bacteria influence metabolic health, mental health, and food cravings. They explore Akkermansia, a keystone strain that maintains gut lining integrity and stimulates natural GLP-1 production, affecting energy, blood sugar, and mood. Colleen explains what depletes beneficial bacteria and offers practical guidance on rebuilding gut health through diet, fiber, polyphenols, and targeted probiotics. This show is made possible by: Bon Charge: Get 15% off when you order at boncharge.com and use promo code COMMUNE  Stemregen: Get 20% off your first order at stemregen.co/commune with the code COMMUNEPOD Vivobarefoot: Try Vivobarefoot risk-free with a 100-day return guarantee, and get 15% off your order at vivobarefoot.com/commune. LMNT: Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at drinklmnt.com/commune. Sunlighten:  Visit sunlighten.com/commune and use code COMMUNE when you fill out the “Get Pricing' form to save up to $1,600 on your purchase.

As more patients present with digestive sensitivity and increasingly restricted diets, restoring gut resilience has become a central clinical challenge. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, about emerging microbiome science and practical strategies for supporting microbial balance, dietary tolerance, and metabolic health. The discussion explores next-generation probiotic strains, fiber diversity, IBS patterns, and real-world approaches clinicians can use to help patients rebuild microbiome resilience and expand diet diversity in practice. Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/ GUEST DETAILS Colleen Cutcliffe, PhD, is CEO and Co-Founder of Pendulum Therapeutics, where she focuses on advancing microbiome science and metabolic health through next-generation probiotic research. She holds a PhD in Biochemistry and Molecular Biology from Johns Hopkins University and brings more than 25 years of experience across biotechnology, pharmaceuticals, and academic research. THANKS TO OUR SPONSOR Pendulum Therapeutics - http://PendulumLife.com/Kara20 Email: hello@pendulumlife.com EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Using next-generation probiotics like live Akkermansia, Pendulum is designed to go beyond gut health to support metabolism. Visit http://PendulumLife.com/Kara20 and use code KARA20 for 20% off your first membership order. CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/newsletter/ Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioagequiz YouTube: https://tinyurl.com/hjpc8daz Instagram: https://www.instagram.com/drkarafitzgerald/ Facebook: https://www.facebook.com/DrKaraFitzgerald/ DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw

Send us Fan MailYou've tried probiotics. They helped — for a little while. Then the bloating came back. The reactivity returned. Whatever shift you felt didn't hold.So you tried something else. Different probiotic, different protocol, different elimination approach. Same pattern. Brief improvement, then backslide.It's not that nothing helps. It's that nothing holds.In this episode I'm going to tell you why. And it's probably not what you think.The problem isn't the wrong probiotic or a diet that isn't strict enough. The problem is that your gut ecosystem has lost its keystone species — the specific organisms that hold the entire system together. And until those are restored, nothing you add is going to stick.I walk through who the keystone species are and what they actually do — Faecalibacterium prausnitzii, Akkermansia, Bifidobacterium, Lactobacillus reuteri, Roseburia — and what the whole system loses when they go missing. Why butyrate production drops and what that costs your gut lining, immune function, motility, and mood. Why fermentation shifts from fiber to protein and produces inflammatory compounds that drive reactivity and brain fog. And why opportunistic species expand — not because they invaded, but because the space opened up.I also cover what disrupts keystone species in the first place — antibiotics, low fiber diversity, chronic stress, mold exposure, common medications — and what restoration actually requires, in the right sequence, at the pace your system can absorb.If you've been doing gut work and keep hitting the same ceiling, this episode will reframe what's been missing.read the full blog post hereSupport the showSupport the podcast  Mineral Foundations Course HEREMinerals & Microbes package HERERewilded Wellness program HEREJoin my newsletter HERE If you are interested in becoming a client and have questions, reach out by emailing me: lydiajoyme@gmail.com  Find me on Instagram : @ Lydiajoy.me

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Audrey: Hi Dr. Cabral, What are your thoughts on retained reflexes? My almost 3 yr old girl has extreme outbursts every day that involves lots of screaming and yelling. I was told retained reflexes could be the problem. She is extremely smart and started talking at a very young age. I know she is too young for any heavy metal detoxes or parasite cleanses so I'm not sure how to help her. I also have a 4 yr old and a NB so having some peace in the home would be nice. Thanks      Cathy: Dear Dr Cabral, I'm so thankful for you! In the past 1.5yrs I've lost 30lbs and still losing more. Approx 160lb. 5'5" 64yo female. paleo diet. No gluten, dairy, grains or refined sugar. Very few deviations. I walk/hike 4-5x wk. Recently added strength. Hashimotos- currently NP Thyroid med 30mg.Taking med for 3 mo. Chol. is higher than ever 320. Triglycerides 143 HDL 57 LDL 236 ApoB 157 HDL-P total-29.3 Small LDL-P - 846 LDL size 21.5 CRP- 1.31 Iron runs high 163. I do not have hemochromatosis. TSH- 3.62 Reverse T3-12.5 Thyr perox- 65 Gut testing: Enterococcus spp- 4.60e8 Akkermansia muc -0 Bacteroidetes- 4.97e11 Firmicutes- 1.15e10 Bacciklus spp- 4.31e6 Enterococcus faecium- 4.35e5 Klebsiella spp- 1.35e5 Klebsiella pneumoniae- 3.45e5 Beyond thankful for any insight! God bless you!      Anonymous: Hi Dr. C — Big thanks to you and your amazing team for all you do. Question about purchasing pre-owned items: Are there any health concerns about buying used clothing items or bedding (sheets)? I always wash them before using them. Some people are grossed out about "used bedding," but it seems to be the same as going to a hotel: those aren't new sheets on hotel beds. Thanks.                                                               Sarah: Hello doc! I saw somebody say that red dots (cherry angiomas) on the body can be due to poor bile flow. Curious on your take on this? Cheers!      Basak: I had a quick question I wanted to ask. I divide my time between the Netherlands and Miami, and I maintain the same healthy habits in both locations—clean eating, daily exercise, minimal alcohol, and consistent sleep. I generally feel well and have no other complaints. However, I have noticed that whenever I return to Miami, I consistently experience lower abdominal bloating. I was wondering whether it is possible that environmental factors—such as differences in air quality, water, or other environmental exposures in the U.S.—could be contributing to this reaction. I would appreciate your perspective    Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3698 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Beyond Probiotics: Rebuilding the Gut Microbiome as an Ecosystem with Dr. Oscar Coatzee and Danielle Arnold  and host Dr. Ben Weitz.   [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.]   Podcast Highlights Rethinking Probiotics: Keystone Anaerobes, Butyrate, and Microbiome Ecosystems with Designs for Health Dr. Ben Weitz introduces the Rational Wellness Podcast episode challenging the assumption that gut issues are solved by adding more traditional probiotics, arguing microbiome repair is an ecosystem and function problem. He interviews Dr. Oscar Cozo and Danielle Arnold of Designs for Health about differences between transient aerobic probiotics (e.g., lactobacillus/bifidobacteria) and keystone anaerobic strains that form the microbiome's foundation, can engraft, drive down gut oxygen, and support cross-feeding. They discuss live, refrigerated delivery for anaerobes; a spore-capable keystone strain (Anaerostipes); and a case study showing improved food allergies, normalization of Akkermansia, increased butyrate-related effects, and reduction of opportunists without antimicrobials. They cover butyrate's roles (tight junctions, mucus, immune regulation, HDAC inhibition), fiber and resistant starch strategies, stool testing (GI-MAP additions for anaerobes and short-chain fatty acids), diet restriction concerns, and practitioner support and case report publishing with Designs for Health. 00:00 Show Intro and Mission 01:00 Probiotics vs Ecosystem Thinking 02:56 Aerobes vs Anaerobes Explained 07:06 Keystone Species and Engraftment 09:18 New Anaerobic Strains and Allergy Research 11:06 Live Shipping and Feeding the Strains 14:03 Case Study Crowding Out Dysbiosis 18:03 Rethinking the Five R Protocol 24:26 Testing and Prebiotic Pairings 26:52 Butyrate and Microbiome Benefits 28:40 Conventional Probiotics Still Matter 35:04 Sponsor Break Apollo Wearable 36:37 Crowding Out Pathogens and Fungi Role 39:58 Archaea and Mucosa 41:21 Mucus Layer and Biofilms 43:11 Feeding Keystone Microbes 44:18 Fiber Targets and Tolerance 46:51 Probiotic as SIBO Option 48:54 Resistant Starch Basics 51:52 Stool Test Dysbiosis Patterns 54:32 Akkermansia and Metabolism 56:44 Histamine Bugs and Enzymes 01:02:26 Gut Healing Nutrients 01:05:34 Diet Diversity and Reintros 01:08:21 Wrap Up and Product Details 01:13:10 Podcast Outro and Clinic Info   Dr. Oscar Coatzee has over 25 years experience in psychology and nutrition and is currently the VP of clinical education and practitioner support at Designs For Health. He has a bachelor's degree in psychology and a PhD in Holistic Nutrition and  Doctorate of Clinical Nutrition. Danielle Arnold is a clinical nutritionist and Functional Medicine practitioner and she serves as a clinical support specialist at Designs for Health, training healthcare providers in test interpretation and patient care. Dr. Ben Weitz is available for Functional Nutrition consultations specializing in Functional Gastrointestinal Disorders like IBS/SIBO and Reflux and also Cardiometabolic Risk Factors like elevated lipids, high blood sugar, and high blood pressure.  Dr. Weitz has also successfully helped many patients with managing their weight and improving their athletic performance, as well as sports chiropractic work by calling his Santa Monica office 310-395-3111.

My new book, "The Weight Loss Cure," offers a step-by-step guide to rebuilding your gut ecosystem so you can restore your body's natural weight-control system — no injections required Your gut produces the same GLP-1 hormone that weight-loss drugs like Ozempic mimic, meaning your body already has the natural machinery for appetite control and fat burning Damage from seed oils and low-fiber diets weakens your gut barrier, disrupts GLP-1 signaling, and causes inflammation that blocks weight loss A key gut bacterium called Akkermansia muciniphila helps repair your gut lining, balance blood sugar, and promote natural fat loss — even in its pasteurized, non-living form Restoring gut health begins with repairing the barrier, reducing linoleic acid intake, and gradually reintroducing diverse fibers to produce "Gut Gems" like butyrate that calm inflammation and stabilize metabolism

In this episode, Dr. David Jockers reveals how fasting can help heal your gut lining by reducing mechanical stress, allowing your body to regenerate faster. He explains how a 24-hour fast can trigger intestinal stem cell production, leading to healthier gut cells.   You'll learn how intermittent fasting reduces inflammation throughout the body and balances the immune system, boosting the body's ability to fight chronic conditions. Dr. Jockers shares the science behind fasting's role in regulating T-cells and inflammatory cytokines.   Finally, Dr. Jockers dives into how fasting enhances gut microbiome diversity, which is essential for reducing autoimmunity. By supporting the production of beneficial bacteria like Akkermansia, fasting helps strengthen the gut mucosa and supports immune function. In This Episode:  00:00 Rat Study Fasted 24 Hours 00:18 Podcast Intro And Coaching 03:10 Why Gut Damage Drives Autoimmunity 05:05 Way One Heal Gut Lining 06:58 Way Two Lower Inflammation 07:45 Way Three Boost Microbiome Diversity 09:24 Akkermansia And Mucus Layer 12:11 Pruning Analogy For Gut Balance 14:34 Fasting Windows Raise Akkermansia 15:29 Way Four Mitochondria Resilience 17:21 Four Ways Recap And Farewell 18:04 Podcast Outro And Reviews Start 2026 off right with better sleep, more energy, and less stress. CB Distillery's CBD products have over 2 million satisfied customers and offer premium, third-party tested options for sleep, mood, pain relief, and stress management. With no artificial dyes or fillers, you can trust the quality. And, if you're not completely satisfied, they offer a 100% money-back guarantee. Visit CBDistillery.com and use code DRJOCKERS for 25% off your order. (Note: Product availability may vary by state.)   Hair loss isn't just about age—it's about hair follicles getting stuck. AnaGain Nu by Purality Health uses a pea sprout extract clinically shown to reactivate follicles and boost regrowth. With their micelle liposomal delivery, your body absorbs it fast and effectively. Try it risk-free with a 180-day money-back guarantee and get a buy-one-get-one-free deal at RenewYourHair.com/DRJ.   "Fasting helps heal the gut lining by taking mechanical stress off the gut, allowing for faster regeneration." ~ Dr. Jockers     Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio     Resources: Visit CBDistillery.com and use code DRJOCKERS for 25% off Visit http://RenewYourHair.com/DRJ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/   If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/ 

In this episode, we go deep on the real drivers of aging, performance, and long-term health.We break down why poor sleep becomes exponentially more damaging as you age, how oxygen saturation impacts recovery, what “sleep burden” actually means, and why tracking O2 might be one of the most important metrics after 50.We discuss senolytic cells, mitochondrial function, hyperbaric oxygen, creatine and energy substrates, and why blindly experimenting with peptides can be riskier than people think.We also dive into gut health — restoring Bifidobacteria and Akkermansia, rhythmic pulsing vs daily supplementation, breast milk components, resistant starch, and how microbiome balance affects immunity, fat loss, and inflammation.Follow Joel Green here:https://linktr.ee/joelgreene?utm_source=ig&utm_medium=social&utm_content=link_in_bioSpecial perks for our listeners below!

Colleen Cutcliffe (Pendulum Therapeutics) is a doctor of biochemistry and microbiology and CEO and co-founder of Pendulum Therapeutics. Colleen joins the Armchair Expert to discuss starting a microbiome supplement company inspired by her premature daughter who had to take antibiotics, applying hyenas' evolved ability to digest rotting meat to study gut bacteria, and how fecal transplants reliably help treat C. diff. Colleen and Dax talk about the real linkages between microbiome and depression, obesity, and more, how the body's natural GLP1s function, and why a healthy gut is a resilient gut. Colleen explains her wooden fence analogy to illustrate leaky guy syndrome, remarkable results from experiments giving mice Akkermansia, and that the beauty of the microbiome is that everything is recoverable.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Tired of doing “everything right” and still feeling inflamed, foggy, and out of sync with your body? We dig into a clear, faith-forward plan to restore energy, steady hormones, and heal the gut using targeted, physician-grade supplements and practical daily habits. No fads. No hype. Just clean science, smart dosing, and tools you can actually stick with.We start by reframing the problem: modern food and stress deplete minerals, overwhelm the liver, and skew our fat balance. That's why stacked support works best. We unpack Hormone Tame as a five-in-one: activated B vitamins for methylation, mitochondrial nutrients for energy, and polyphenols that help metabolize estrogen so periods calm and mood steadies. Then we tackle the omega equation—why seed oils drive inflammation and how a high-purity omega-3, plus magnesium, can flip the script on aches, sleep, and resilience.From there, we build your gut plan. A medical-food style protein with L-glutamine soothes IBS and feeds the lining. Digestive Lift adds enzymes, gentle acid, and ox bile to prevent bloat and help you handle healthy fats. For microbiome balance, Biome Lift stabilizes daily while Spore Lift acts like a bouncer when SIBO or post-travel trouble hits. We also introduce a fiber you won't fear: a diverse prebiotic blend that increases short-chain fatty acids, nudges Akkermansia for metabolic health, and naturally boosts GLP-1 to curb cravings.Detox gets a reset with a true 3-2-1 approach—opening phase 3 and 2 before phase 1 so toxins exit rather than recirculate. Expect less bloat, brighter skin, and steadier energy when you rotate this seasonally and keep daily support with Slim Lift. If you're stepping down from GLP-1 meds or want a stimulant-free metabolism boost, MetaboLift pairs GLP-1 support with AMPK activation to quiet “food noise” and raise your burn without wrecking appetite or sleep.This is how faith, functional medicine, and simple choices meet: whole foods, better fats, prayer, rest, and supplements that respect how the body actually works. Subscribe, share with a friend who needs hope, and leave a review to help more women find real healing.✨ Join the EMPOWERED BY FAITH: 5 Days To A Lighter You Challenge!

339: Most people listening are already aware of the foods and ingredients that disrupt gut health, but what if I told you that the “health food” you're consuming regularly is actually causing your health issues? Today, I'm joined by holistic practitioner and homeopath Marla Pietruszko, and we talk about her personal health journey, including healing from mold exposure she experienced as a toddler, along with her gut, skin, and parasite issues, and how she healed, and how you can too. We also dive into certain foods and supplements you should avoid if you have IBS, the do's and don'ts of food combining, and other popular health fads that are simply bogus red flags. Topics Discussed:→ Akkermansia for gut lining repair→ Do's and don'ts of food combining→ Mold exposure→ Supplements you should not be taking if you have IBS→ NAD+→ Diatomaceous earth for parasites→ E. coli (friend or foe?) in the gut→ Is sea moss really good for us? As always, if you have any questions for the show, please email us at digestthispod@gmail.com. And if you like this show, please share it, rate it, review it, and subscribe on your favorite podcast app. Sponsored By:  → Fatty15 | For 15% off the starter kit go to https://fatty15.com/digest → Bethany's Pantry | Go to https://bethanyspantry.com/ and use code PODCAST10 for $10 anything! Timestamps: → 00:00:00 - Introduction → 00:05:15 - Rapid Fire Q&A → 00:09:50 - Healing From Mold → 00:14:09 - Medical Failures → 00:18:37 - 10 Foods to Avoid → 00:23:08 - Protein & Produce Limits → 00:25:51 - Food Prep & Gut Health → 00:27:31 - Food Combining Basics → 00:29:19 - Protein Powders → 00:30:27 - Akkermansia & Leaky Gut → 00:33:43 - Gut-Damaging Foods → 00:37:55 - Parasites & Detox → 00:41:19 - NAD+ & Aging → 00:44:26 - Supplements to Avoid → 00:47:44 - Superfoods & Powders Further Listening: →  Does Food Combining Help or Harm Gut Issues? | BOK Check Out Marla: → Website → Instagram Check Out Bethany: → Bethany's Instagram: @lilsipper → YouTube → Bethany's Website → Discounts & My Favorite Products → My Digestive Support Protein Powder → Gut Reset Book  → Get my Newsletters (Friday Finds) Learn more about your ad choices. Visit megaphone.fm/adchoices