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Doctor and special correspondent, Avir Mitra takes Lulu on an epic journey live on stage at a little basement club called Caveat, here in New York. Starting with an ingredient in breastmilk that babies can't digest, a global hunt that takes us from Bangladesh to the Mennonite communities here in the US, we discover an ancient symbiotic relationship that might be on the verge of disappearing. So sip a vicarious cocktail, settle in, and explore the surprising ways our bodies forge deep, invisible connections that shape our lives.This live show is part of a series we are doing with Avir that we are calling “Viscera.” Each event is conversation that takes the audience on journey into a quirk or question or mystery inside of us, and gives them a visceral experience with the viscera of us. The previous installment of the series, was called “How to Save a Life.”Special thanks to Tim Brown, David Mills, Carlito Lebrilla, Bethany Henrik, Danielle Lemay, Katie Hinde, Jennifer Smilowitz, Angela Zivkovic, Daniela Barile, Mark UnderwoodEPISODE CREDITS:Reported by -Avir Mitrawith help from - Anisa VietzeOriginal music from - Dylan KeefeSound design contributed by - Dylan Keefe, Ivan BarenFact-checking by -Natalie Middleton.Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.Leadership support for Radiolab's science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.
Matters Microbial #91: You Are What Your Genes Feed Your Microbiome May 16, 2025 Today, Dr. Emily Davenport, Assistant Professor in the Department of Biology and Huck Institutes of the Life Sciences at Penn State University, joins the #QualityQuorum to tell us about the research her team does, studying how our own genes impact our microbiomes. Host: Mark O. Martin Guest: Emily Davenport Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A description of GWAS (“Genome Wide Association Study”). Here is an introductory video about the concept. An explainer on organoids. An essay about the diversity of the host microbiome (i.e. is there a “healthy” microbiome?). An article of the work of Dr. Sarkis Mazamian on how individual host genes and bacterial genes can impact the microbiome. A nice write up for Dr. Mazamian's work showing how host genes and bacterial genes can work together…or not. An oldish video of how the infant microbiome develops over time by Dr. Rob Knight's research group. An article on the same topic from Dr. Ruth Ley. An essay on the mucosal microbiota, rather than the fecal microbiome. An interesting member of the human microbiome, Akkermansia that might be related to obesity. Another interesting member of the human microbiome, Bifidobacterium, which appears to be associated with host lactose metabolism. Yes, there is a Giant Microbes plush toy. An overview of the impact of host genetics on the microbiome by Dr. Davenport. A definition of heritability. An overview of the Hutterites and how their study has advanced genetics. An explainer of the power of twin studies in genetics. A fascinating article about ancient dental plaque microbiome by Dr. Davenport and others. Dr. Davenport's faculty website. Dr. Davenport's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
C'est une question que beaucoup se posent au moment de passer au rayon boulangerie : faut-il choisir le pain blanc, moelleux et classique, ou le pain complet, souvent jugé plus rustique ? D'un point de vue nutritionnel, la réponse est claire : le pain complet est généralement meilleur pour la santé. Voici pourquoi.Le pain blanc est fabriqué à partir de farine raffinée, dont on a retiré le son (la couche extérieure du grain) et le germe (la partie nutritive). Ce procédé donne une texture plus légère, mais prive le pain de fibres, vitamines et minéraux essentiels. À l'inverse, le pain complet est issu de farine intégrale, contenant toutes les parties du grain. Résultat : il est bien plus riche en nutriments.Selon les données de l'Agence nationale de sécurité sanitaire de l'alimentation (ANSES), 100 grammes de pain complet contiennent en moyenne 6 à 7 g de fibres, contre 2 à 3 g seulement pour le pain blanc. Or, les fibres jouent un rôle clé dans la régulation du transit intestinal, la satiété (ce qui aide à limiter le grignotage) et même dans le contrôle de la glycémie. En ralentissant la digestion, elles évitent les pics de sucre dans le sang que provoque souvent le pain blanc.Une étude scientifique publiée dans le British Journal of Nutrition en 2017 par Y. Benítez-Páez et ses collègues a démontré que la consommation régulière de pain complet améliore la diversité du microbiote intestinal, ce qui est associé à un système immunitaire plus robuste et à une réduction des inflammations chroniques. Les chercheurs ont suivi deux groupes de participants pendant 8 semaines : ceux qui mangeaient du pain complet ont vu une augmentation significative de certaines bactéries bénéfiques, comme Bifidobacterium et Lactobacillus, par rapport au groupe pain blanc.De plus, les céréales complètes sont associées à une réduction du risque de maladies cardiovasculaires. Une méta-analyse de 2016 publiée dans The BMJ, regroupant 45 études, a montré qu'une consommation élevée de céréales complètes (dont le pain complet) est liée à une diminution de 22 % du risque de maladie cardiaque et à un taux de mortalité global réduit.Cela dit, il faut rester vigilant : tous les pains "complets" ne se valent pas. Certains pains industriels utilisent de la farine blanche enrichie de son, ce qui ne reproduit pas les bienfaits du grain entier. Privilégiez les pains portant la mention "farine complète" ou "farine intégrale", de préférence bio, et fabriqués par des boulangers artisanaux.En résumé, pour votre santé digestive, cardiovasculaire et métabolique, le pain complet l'emporte haut la main sur le pain blanc. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
On the previous two episodes we learned about the dangers of antibiotics and what we can use instead. But what do you do if you've taken antibiotics and your gut is now a mess? On this episode of Vitality Radio, Jared shares exactly how you can rebuild your gut microbiome in the aftermath of antibiotics or other assaults on your system. He dives into the concept of gut dysbiosis and specifically, leaky gut. You'll learn the causes and symptoms, such as food sensitivities, brain fog, mood disturbances and autoimmune disorders. You'll learn the difference between Probiotics, Spores, Postbiotics, and Prebiotics and how these are all important to heal and seal the gut wall, and restore balance and critical diversity in your microbiome. Products DiscussedAdditional Information:#527: The Dangerous Truth About Antibiotics#528: Natural Alternatives to Antibiotics: How to Support Your Body Through Common Challenges#507: Comprehensive Digestive Support to Get Your Gut ‘Back On Tract'!Visit the podcast website here: VitalityRadio.comYou can follow @vitalitynutritionbountiful and @vitalityradio on Instagram, or Vitality Radio and Vitality Nutrition on Facebook. Join us also in the Vitality Radio Podcast Listener Community on Facebook. Shop the products that Jared mentions at vitalitynutrition.com. Let us know your thoughts about this episode using the hashtag #vitalityradio and please rate and review us on Apple Podcasts. Thank you!Just a reminder that this podcast is for educational purposes only. The FDA has not evaluated the podcast. The information is not intended to diagnose, treat, cure, or prevent any disease. The advice given is not intended to replace the advice of your medical professional.
Story at-a-glance Studies show people with multiple sclerosis (MS) have different gut bacteria than healthy people, with too much of certain bacteria types and not enough of the helpful ones The ratio between the bacteria Bifidobacterium and Akkermansia serves as a biomarker for MS progression, with this pattern appearing consistently across patients worldwide Normally beneficial Akkermansia bacteria can become harmful in MS when Bifidobacterium levels drop, damaging the protective mucin layer in the gut and increasing inflammation Multiple studies confirm MS patients have lower levels of beneficial bacteria that produce short-chain fatty acids like butyrate, which normally help reduce inflammation Simple dietary changes support gut health, including proper carbohydrate intake (200 to 350 grams daily), increasing fiber gradually if your gut is healthy and avoiding processed foods and vegetable oils
After spending thousands on fertility treatments—including multiple medicated cycles, IUI, and two failed IVF attempts—Angie was devastated when doctors told her to consider egg donation or adoption. Everything looked "normal" on paper, but she still couldn't get pregnant. In this episode, Dr. Aumatma Simmons, a board-certified naturopathic endocrinologist and fertility specialist with nearly 15 years of experience, shares Angie's transformational story—and how healing her gut (not her reproductive system) finally led to a healthy pregnancy.Dr. Aumatma is;A licensed Naturopathic Doctor for 15 years, with additional board certification in Naturopathic EndocrinologyCreator of The Restorative Fertility MethodHost of Egg Meets Sperm Podcast, a Top 5% podcast2x Best-selling author: Fertility Secrets and (in)Fertility: Struggles, Secrets, & SuccessesAwards: Best Naturopathic Medicine Doctor (2015, 2020) and Top Women in Medicine Doctor (2020, 2021), Berkeley Hall of Fame (2022)Interviewed on 100+ podcasts about fertility, pregnancy, and postpartumFeatured as the Holistic Fertility Expert on ABC, FOX, CBS, KTLA, MindBodyGreen, The Bump Has trained hundreds of practitioners around the world in holistic approaches to fertility, and has certified top doctors in the Fertile Foundations™ system Founder of Madre Fertility, with a free Smart Fertility Analysis, to help you better understand blocks to fertility, and create a customized roadmap for the journey.Medical Advisor for Mira Fertility, Element, and Feminade - three awesome leaders in fertility & women's health Key InsightsHow Angie's food sensitivities, digestive symptoms, and microbiome imbalances were silently sabotaging her fertilityThe link between gut bacteria (like Lactobacillus & Bifidobacterium) and hormone balance, implantation, and egg qualityWhy common "healthy" foods like onions, dairy, and raw salads can actually harm your fertility—depending on your microbiomeHow gut healing helped normalize Angie's estrogen metabolism, reduce inflammation, and improve progesterone levels without medicationThe gut-vaginal microbiome connection that impacts implantation and early pregnancyThe exact 4-week gut restoration protocol, using the 4R method (Remove, Replace, Re-inoculate, Repair), tailored for fertility optimizationAdditional Topics CoveredHow leaky gut triggers immune responses that can block implantationThe specific probiotics and nutrients that support both the gut lining and hormone healthHow Dr. Aumatma tracked Angie's hormone shifts in real-time as her gut healedPractical changes in how, when, and what Angie ate to support microbial balanceTimestamps0:00 – Introduction & Angie's 3-Year Fertility Struggle4:20 – Symptoms That Pointed to Gut Imbalances7:15 – Understanding the Estrobolome & Estrogen Recycling10:50 – What Angie's Gut Tests Revealed14:40 – The 4R Protocol: How We Healed Her Gut Step by Step19:30 – Surprising Foods That Were Hurting Her Fertility23:15 – Hormonal Changes After Gut Healing26:00 – Do You Have These Gut-Fertility Clues?30:00 – How You Can Get Started on Healing TodayConnect with ME Instagram:
Et si, demain, on traitait l'anxiété non pas avec des médicaments, mais… avec des bactéries ? Aussi surprenant que cela puisse paraître, cette idée est de plus en plus prise au sérieux par les chercheurs. Une nouvelle revue d'études publiée en 2023 dans la revue General Psychiatry affirme que le microbiote intestinal – c'est-à-dire l'ensemble des micro-organismes qui vivent dans notre intestin – joue un rôle clé dans la survenue de troubles anxieux. Et qu'il pourrait aussi faire partie de la solution.Les scientifiques parlent aujourd'hui de l'axe intestin-cerveau. Ce lien étroit entre nos intestins et notre système nerveux central est désormais bien établi. En effet, notre intestin produit à lui seul 90 % de la sérotonine de notre corps, un neurotransmetteur impliqué dans la régulation de l'humeur, du sommeil… et de l'anxiété.Mais ce que met en lumière cette revue, c'est que certaines bactéries spécifiques du microbiote pourraient moduler l'anxiété. En analysant les résultats de 21 essais cliniques, les auteurs montrent que la prise de psychobiotiques – autrement dit, de probiotiques ciblés – a permis de réduire les symptômes anxieux chez de nombreux participants, parfois avec une efficacité comparable à celle des traitements classiques.Alors, comment ces bactéries agissent-elles ? Plusieurs mécanismes sont envisagés. D'abord, elles participeraient à la production de neurotransmetteurs comme la dopamine ou la GABA, connus pour leurs effets calmants sur le cerveau. Ensuite, elles pourraient réduire l'inflammation chronique, souvent observée chez les personnes anxieuses. Enfin, elles influenceraient la réponse au stress via le système immunitaire et le nerf vague, la grande autoroute nerveuse qui relie l'intestin au cerveau.Il ne s'agit pas de dire que les anxiolytiques actuels n'ont plus leur place. Mais les chercheurs estiment que, dans certains cas, les probiotiques pourraient constituer une alternative naturelle, ou au moins un complément efficace, avec moins d'effets secondaires.Des bactéries comme Lactobacillus ou Bifidobacterium sont aujourd'hui les plus étudiées. Elles se trouvent dans certains aliments fermentés comme le yaourt, le kéfir, ou encore sous forme de compléments.Bien sûr, ces recherches en sont encore à leurs débuts, et tous les experts appellent à la prudence. Mais une chose est sûre : notre ventre n'est pas seulement le siège de la digestion. C'est aussi un acteur essentiel de notre santé mentale. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Chronic stress disrupts the gut microbiome by altering the HPA axis and increasing inflammation, leading to dysbiosis and reduced beneficial bacteria like Lactobacillus and Bifidobacterium. In this episode, we discuss how to mitigate these effects and restore gut health through a multifaceted approach. Key Strategies: Regulate Stress & Lower Cortisol: Practices like mindful breathing and HRV training Adaptogens (Ashwagandha, Rhodiola) Morning sun exposure to stabilize cortisol Support Gut Integrity & Reduce Inflammation: L-Glutamine and colostrum for gut repair Bone broth and butyrate to heal the gut lining Rebuild Beneficial Bacteria: Probiotics: Lactobacillus rhamnosus GG and Bifidobacterium longum Prebiotics: Resistant starch, polyphenols, and fermented foods Support Vagus Nerve Function: Cold exposure and low-intensity exercise to balance the nervous system Improve Sleep: Supplements like Magnesium Glycinate and L-Theanine to support relaxation and reduce cortisol spikes By following these strategies, you can restore microbial balance, reduce inflammation, and enhance resilience to stress. Why Work with a FDN Practitioner? When addressing stress-induced dysbiosis, it's crucial to test, not guess. Working with a Functional Diagnostic Nutrition Practitioner (FDNP) allows you to personalize your protocol through functional lab testing. This approach eliminates the cycle of trial and error, providing precise insights into your unique health needs. A personalized, evidence-based plan can help you achieve optimal results and sustainable health outcomes.
Send us a textShort Summary: How diet shapes the gut microbiome and impacts health, with microbiologist Dr. Peter Turnbaugh breaking down the complex science.About the guest: Peter Turnbaugh, PhD is a professor of microbiology and immunology at the University of California, San Francisco, where he leads a lab studying the gut microbiome's role in nutrition and drug response.Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Full transcript and other information on Substack.Episode Summary: Nick talks to Peter Turnbaugh discuss the pitfalls of oversimplified diet labels in research, Turnbaugh's studies comparing plant-based and animal-based diets in humans, and how these shifts rapidly alter gut microbes and short-chain fatty acid profiles. Key Takeaways:The term “high-fat diet” in research is often misleading, as it can include high carbs and vary widely, complicating study comparisons.In a 2014 study, switching humans to a plant-based (high-fiber) or animal-based (ketogenic, no-fiber) diet changed their gut microbiome within one day, showing its remarkable adaptability.Ketogenic diets reduce Bifidobacterium in the gut, which may lower inflammation-linked immune cells (Th17), potentially aiding conditions like multiple sclerosis.Short-chain fatty acids (e.g., butyrate) don't just come from fiber; they persist even on zero-fiber ketogenic diets, hinting at alternative microbial pathways.Gut microbes can activate or deactivate drugs, like antibiotics or digoxin, suggesting microbiomes may explain why drugs work differently across individuals.Ketone bodies like BHB alone can mimic some ketogenic diet effects on the microbiome and immunity, simplifying research and hinting at therapeutic potential.Related episode:M&M #203: Metagenomics, Microbiome Transmission, Gut Microbiome in Health & Disease | Nicola Segata*Not medical advice.Support the showAll episodes, show notes, transcripts, etc. at the M&M Substack Affiliates: Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Readwise: Organize and share what you read. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription. MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils or artificial ingredients. Use code MIND for 20% off. For all the ways you can support my efforts
One in three Americans take probiotics, but are they getting the benefits they expect? In this interesting episode, Dr. Odell digs into the science of these beneficial microorganisms and separates fact from fiction. Discover why strain specificity matters, what may be a better choice for some people, and how the latest breakthroughs in probiotic technology could transform your health outcomes. From boosting immunity to improving mental health, he'll explore the wide-ranging benefits backed by scientific evidence. Learn about postbiotics, spore technology, and personalized approaches that are revolutionizing how we think about gut health. Whether you're a probiotic veteran or considering them for the first time, this comprehensive guide provides actionable advice for making informed decisions about your microbiome. Get practical tips on choosing the right strains, proper timing, and who should (or shouldn't) be taking these supplements. Beyond the marketing hype, this episode equips you with everything you need to know about the power of probiotics for optimal health.
A recent study suggests that long-term yogurt consumption, which typically contains a genus of probiotic Bifidobacterium, is associated with a 20% decreased incidence of colorectal cancer. Listen in this week as Dee explains how Bifidobacterium works in the gut, why it may protect against the formation of tumors, and how much yogurt you need to eat each week to get the same amount reported in the study.References:Ugai, S., Liu, L., Kosumi, K., Kawamura, H., Hamada, T., Mima, K., Arima, K., Okadome, K., Yao, Q., Matsuda, K., Zhong, Y., Mizuno, H., Chan, A. T., Garrett, W. S., Song, M., Giannakis, M., Giovannucci, E. L., Zhang, X., Ogino, S., & Ugai, T. (2025). Long-term yogurt intake and colorectal cancer incidence subclassified by Bifidobacterium abundance in tumor. Gut Microbes, 17(1). https://www.tandfonline.com/doi/full/10.1080/19490976.2025.2452237Link to Probiotics: https://amzn.to/41jCNyP
In this episode of Should You Take This?, host Joe Cohen dives deep into one of his top three favorite probiotics—Bifidobacterium longum. If you've struggled with bloating, digestion issues, or simply want to optimize your gut health, this probiotic might be a game-changer.Joe shares his personal experience with B. longum, breaking down its effectiveness in reducing gas, improving digestion, and supporting overall health. He also explores the scientific research behind it, discussing its potential benefits for mood, immunity, and inflammation.Tune in to learn whether B. longum is the right probiotic for you and how it fits into Joe's biohacking regimen. Don't miss this insightful episode packed with actionable tips to enhance your well-being!- Check out SelfDecode: https://selfdecode.com/- Join Joe's online community: https://thejoecohenshow.com/
#140 - Unlocking the Power of Your Own GLP-1 Naturally! Gut Health, Weight Management, and Natural Boosters Have you ever wondered what GLP-1 agonists are and why they're making headlines? In this episode, we dive deep into the science of GLP-1, a hormone critical for controlling metabolism, appetite, and blood sugar levels. Discover how it's produced in your gut, its connection to your microbiome, and why medications like semaglutide and liraglutide are becoming household names in weight management and diabetes care. But here's the exciting part—you don't need a prescription to support your GLP-1 production! Learn how specific foods, probiotics, and lifestyle changes can naturally boost your body's ability to make this essential hormone, helping you achieve sustainable weight loss, improved energy, and vibrant health. Probiotics mentioned: Bifidobacterium adolescentis, Bifidobacterium longum, Lactobacillus acidophilus, Lactobacillus rhamnosus, Lactobacillus plantarum, and Saccharomyces boulardii (for during and post-antibiotic use) Join the conversation: What's your experience with GLP-1? Share your thoughts with us on social media or in the comments! Subscribe, Share & Review: If you enjoyed this episode, please hit that subscribe button, share with others, and leave us a review. Your support helps us reach more listeners - thanks! The primary purpose of The Pretty Well Podcast being to educate. This content is for informational and educational purposes only. It is not intended to provide medical advice nor to take the place of such advice or treatment from a personal physician. By listening to this content, you agree to consult your own physician or qualified health professional regarding specific health questions. Neither Lisa Smith, The Pretty Well Podcast, nor any guest takes responsibility for possible health consequences of any person or persons following the information in this educational content. All listeners of this content, especially those who are pregnant or taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program. The Pretty Well Podcast is for private non-commercial use and our guests do not necessarily reflect any agency, organization, or company that they work for. In addition, opinions of interview guests do not necessarily reflect the opinions of Lisa Smith and/or The Pretty Well Podcast. This content is not guaranteed to be correct, complete, or up to date.
In this episode, we have a recording taken from the launch of Follow Your Gut, with co-creators Briony Barr & Gregory Crocetti, writers Lisa Stinson & Ailsa Wild and illustrator Ben Hutchings. In this graphic novel, one meets the ecosystem inside them ... A timid Bifidobacterium named Biffy is forced to leave their family and become part of a new community, in the gut of a newborn human baby. Follow Your Gut is a comic that ate a biology textbook. It's an epic adventure set over the first three years of a new life, exploring one of the most important relationships you will ever have - the one with your gut microbiome.
The history of fermented foods like beer, bread, and other foods can be traced back thousands of years to ancient civilizations in China and Egypt. This ancient technology was originally used to preserve foods when refrigeration was not an option. While less common in modern industrialized civilizations, we're now realizing that fermented foods play a major role in gut microbiome diversity, which is a biomarker for overall health. Join our conversation with Dr. John Leech, Technologist at Teagasc in County Cork, Ireland to learn all about the history and how cutting-edge technologies are being applied to research in food fermentation. John shares his story of how he found this field of research and how he's now headlong into striving to understand and harness the power of fermented foods. We learn about the complex microbial communities that define and deliver the health benefits of these foods, but we also hear about how this biological complexity makes them inherently irreproducible. Foods like kimchi, sauerkraut, kombucha, tepache, milk kefir, and water kefir are produced from fermentation, facilitated by complex communities of microbes. Consumption of fermented foods can alter our gut microbiome, which has been shown to affect obesity, inflammation, longevity, and efficacy of drug treatments. John and his team are using qPCR, NGS, and other methods to characterize the microbial consortia used to produce these foods. They're now working to figure out how to simplify the consortium while still delivering health benefits, all while making the process reproducible and scalable Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague. Download Transcripts: Speaking of Mol Bio Podcast | Thermo Fisher Scientific - US Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology.
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Today we're talking all about the link between gut health and mental wellness for women navigating midlife challenges like perimenopause and menopause. I'm joined by Tina Anderson, CEO and co-founder of Just Thrive. Tina shares her journey from a high-stress career to discovering the profound impact of the gut microbiome on her own hormonal balance and mental state. We discuss innovative spore-based probiotics that survive the gastric environment and significantly alter gut flora, offering promising benefits for conditions such as stress, anxiety, autoimmune diseases, and chronic inflammation. We also give advice on diet, lifestyle changes, and the potential of probiotics to revolutionize mental wellness and hormone balance. In this episode: Why hormonal changes during midlife disrupt the gut microbiome and impact mental state. An introduction to innovative probiotics and prebiotics designed to support gut health. The science behind Bacillus spores and their ability to survive the harsh gastric environment. How spore-based probiotics can significantly alter gut flora for better health. Why a healthy microbiome effectively manages autoimmune diseases and mental health issues. The relationship between gut health and brain function, including neurotransmitter production and inflammation. Details on a study from the University of North Texas revealing leaky gut prevalence in healthy individuals. How spore-based probiotics can help tackle health challenges like asthma, allergies, and chronic diseases. Differences between spore-based probiotics and traditional probiotics in surviving the gastric system. How the role of gut health in processing hormones impacts mental health. Just Thrive's flagship product with Bacillus strains aiding gut health and mental wellness. Bifidobacterium longum 1714's role in reducing stress perception and balancing cortisol levels. How to improve gut health, reduce reliance on SSRIs, and manage stress. What connection exists between prebiotics, probiotics, and overall wellness. Testimonials highlighting the transformative effects of gut health on energy levels. Sponsors Get 10% off our Bioidentical Hormone Cosmetic Creams with coupon customer10 here. https://karenmartel.com/shop/ Happy Mammoth: For a limited time, you can get 15% off Hormone Harmony and on your entire first order at happymammoth.com just use the code KM15 at checkout. Are you in peri or post menopause and looking to optimize your hormones and health? At Hormone Solutions, we offer telemedicine services and can prescribe in every U.S. state, as well as in British Columbia, Alberta, and Ontario in Canada. Visit karenmartel.com to explore our comprehensive programs: Bioidentical Hormone Replacement Therapy Individualized Weight Loss Programs Peptide Therapy for weight loss Interested in our NEW Peptide Weight Loss Program? Join today and get all the details here. Join our Women's Peri and Post Menopause Group Coaching Program, OnTrack, TODAY! Your host: Karen Martel Certified Hormone Specialist, Transformational Nutrition Coach, & Weight Loss Expert Karen's Facebook Karen's Instagram
Send us a textEffects of a live versus heat-inactivated probiotic Bifidobacterium spp in preterm infants: a randomised clinical trial.Athalye-Jape G, Esvaran M, Patole S, Nathan EA, Doherty DA, Sim E, Chandrasekaran L, Kok C, Schuster S, Conway P.Arch Dis Child Fetal Neonatal Ed. 2024 Aug 17:fetalneonatal-2023-326667. doi: 10.1136/archdischild-2023-326667. As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!
Jen Donovan is a gut-brain axis specialist who completely rebuilt her life and career as a result of her experience with severe chronic illness. Jen has diverse and comprehensive training including a master's of science in family therapy, a Tension and Trauma Releasing Exercises certification, a Nutritional Therapy Practitioner certification, and a Gut and Psychology Syndrome certification. She is also the author of Rebuild Yourself: Whole Body Practices to Heal Your Brain and Your Nervous System. Through her personal and professional journey, Jen has developed Six Support Protocols to provide a clear, structured, evidence-based, and all-encompassing approach to addressing gut-brain axis neurological issues and finding a thriving life again. In our conversation, we explore Jen's healing journey from Mast Cell Activation Syndrome, her work with clients on trauma release and nervous system regulation, and how she works with clients with complex chronic illnesses. She shares the series of chronic health challenges that led her to change careers and subsequently prove herself wrong about mental health challenges. She highlights effective nervous system regulation practices, nutrients and supplements that can manage histamine symptoms and nervous system regulation, effective somatic experiencing and shaking exercises, and tactics for practitioners to set realistic timelines that will help patients find success in their healing journey. I'm your host, Evelyne Lambrecht, thank you for designing a well world with us. Episode Resources: Jen Donovan - https://wholebodyhealingwithjen.com/ Jen's Book - https://www.amazon.com/Rebuild-Yourself-Practices-Nervous-System/dp/B0BRZ1R49C/ Design for Health Resources: Designs for Health - https://www.designsforhealth.com/ Research Blog: Stinging Nettle: A Potent Herb to Support Immune Health - https://www.casi.org/stinging-nettle-support-immune-health Nutrition Blog: Clinical Studies Investigate the Role of Lactobacillus and Bifidobacterium in Mood Health - https://www.casi.org/role-of-lactobacillus-and-bifidobacterium-in-mood-health Research Blog: Spotlight on Benfotiamine - https://www.casi.org/node/640 Science Blog: How the Gut-Brain Axis May Play a Role in Certain Neuropsychiatric Disorders - https://www.casi.org/node/1495 Research Blog: The Relationship Between Histamine Intolerance and Gastrointestinal Health - https://www.casi.org/relationship-between-histamine-intolerance-and-gastrointestinal-health Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog. https://www.designsforhealth.com/research-and-education/education Chapters: 00:00 Intro. 03:44 A series of chronic health challenges led Jen to change careers and prove herself wrong about mental health challenges. 05:21 The symptoms that led Jen to a diagnosis and a root cause approach to healing chronic health issues. 09:17 Seeking answers for herself led Jen to the world of natural health options. 12:54 The incorrect association between the physical and mental symptoms of the gut-brain axis and mast cell disorders. 14:32 Although Jen was finding answers, she didn't immediately start implementing new information into her practice. 15:55 Two years of healing included several aspects of natural healing and advanced somatic nervous system regulation techniques. 19:30 Nervous system regulation practices that Jen has implemented into her work with patients, including allowing shaking when the body demands it. 25:47 Shaking exercises for stress management and stimulation of the neurogenic tremor response from the brain stem. 28:55 Somatic experiencing includes much more than simply noticing sounds and colors. 35:32 Jen's dietary recommendations and tactics for empowering patients to stick with a restricted GAPS diet. 42:33 Dietary timelines for adding new foods while balancing the gut microbiome. 47:17 Setting realistic patient expectations for a years-long timeline for healing. 51:19 Jen recommends nutrients and supplements that help manage histamine symptoms and nervous system regulation. 57:50 The importance of building muscle mass and addressing posture in healing. 1:00:00 The structure of Jen's business is designed to meet the needs of every type of patient. 1:02:40 Jen's favorite supplements, top personal well-being practices, and the fad-following ideas she has changed her mind about in her years of practice.
Did you know that supplementation can improve depression and anxiety? A surprising new study has found that supplements can also enhance the effectiveness of popular antidepressant medications! Learn more, watch now.
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Three exciting new studies have found that probiotics improve diarrhea, constipation, bloating, pain and anxiety! In this episode, I'll break down this new research and help you determine the best protocol for each condition. Watch now!
In this episode, we explore the role of probiotics in managing histamine levels and mast cell activation syndrome (MCAS), particularly in the context of rebuilding the gut microbiome. We discuss which probiotic strains could contribute to symptoms (in the short term) due to their histamine-producing properties, such as Lactobacillus casei and Lactobacillus reuteri, and we highlight beneficial strains that degrade histamine, including Lactobacillus plantarum. Topics: 1. Introduction to Histamine and Mast Cell Activation - Overview of histamine and mast cell activation syndrome (MCAS) - Understanding histamine production 2. Breakdown of White Blood Cells (WBCs) - Origin of WBCs from hematopoietic stem cells in the bone marrow - Categories of WBCs: granulocytes, monocytes, and lymphocytes 3. Examination of Granulocytes - Neutrophils: Role in bacterial infections - Eosinophils: Role in allergic reactions and parasitic infections - Basophils: Involvement in inflammatory and allergic responses through histamine release - Mast Cells: Similarities to basophils, maturation in tissues, and histamine release 4. Examination of Agranulocytes - Monocytes: Phagocytic function and differentiation into macrophages and dendritic cells - Lymphocytes: - T cells: Subtypes and their functions (helper T cells, cytotoxic T cells, regulatory T cells) - B cells: Antibody-mediated immunity - NK cells 5. Mast Cells vs. Basophils - Location and function comparison - Importance in histamine production 6. Mast Cell Activation Syndrome (MCAS) - Triggers of MCAS (infections, environmental exposures, dietary factors, genetic predispositions) - Focus on addressing root causes (lyme?, mold?, candida?, SIBO?, ...) 7. Probiotic Use in the Context of MCAS - Probiotics and pathogenic microbes in the context of mast cell activation 8. Example: Candida and Mast Cell Interaction - Recognition of Candida by mast cells through pattern recognition receptors (PRRs) - Activation pathways and release of histamine and other inflammatory mediators 9. Probiotics and Histamine Production - Probiotic strains that produce histamine - Lactobacillus casei, - Lactobacillus reuteri, - Lactobacillus bulgaricus... - Probiotic strains that do not produce histamine and/or degrade histamine - Bifidobacterium infantis, - Bifidobacterium longum, - Bifidobacterium bifidum, - Bifidobacterium breve, - Lactobacillus plantarum, - Lactobacillus rhamnosus, - Lactobacillus gasseri, - Lactobacillus salivarius Thank you to our episode sponsors: Liver Medic Use code Chloe20 to save 20% on "Leaky Gut Repair" Brendan's YouTube Channel https://x.com/livermedic Tremetes, LLC Use code CHLOE15 to get 15% off Tremetes' Turkey Tail Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
This episode dives into the emerging concept of psychobiotics, exploring how these live (probiotic) microorganisms can positively impact mental health by interacting with the gut-brain axis. We'll provide an in-depth look at the anatomy of the gut lining and the enteric nervous system, explaining how these pathways facilitate communication between the gut and the brain. Additionally, we'll spotlight the psychobiotic Bifidobacterium longum 1714, detailing its mechanisms and benefits for stress and anxiety relief. Topics: 1. General Overview of Psychobiotics - Definition and origin of the term "psychobiotics". - Mental health benefits: alleviating anxiety, depression, enhancing cognitive function, and stress resilience. - Introduction to the gut-brain axis. 2. The Gut-Brain Axis - Detailed explanation of the gut-brain axis. - Overview of the divisions of the nervous system (CNS and PNS). - Further division of the PNS into somatic and autonomic nervous systems. - Division of the autonomic nervous system. - Detailed structure and function of the enteric nervous system (ENS). 3. Gut Lining Anatomy - Layers of the gut lining from the inside out: gut lumen, mucus layers, intestinal epithelium. - Structure and function of the intestinal epithelium and its renewal process. - The role of villi and microvilli in increasing the surface area for nutrient absorption. - Overview of the lamina propria and its immune components. - Overview of the muscularis mucosae 4. Submucosa and Enteric Nervous System (ENS) - Description of the submucosa and its components (blood vessels, lymphatics, nerves). - Detailed structure and function of the submucosal (Meissner's) plexus. - Beyond the submucosa: muscularis externa and the myenteric (Auerbach's) plexus. - Interaction between the ENS and the vagus nerve. 5. Psychobiotics in Action: Bifidobacterium longum 1714 - Introduction to Bifidobacterium longum 1714 and its mental health benefits. - Production of key metabolites (SCFAs, serotonin, GABA) and their roles. - Interaction of metabolites with the ENS and the vagus nerve. - Detailed pathway of signals from the gut to the brain. 6. Other Notable Psychobiotics - Quick overview of other psychobiotics studied for mood regulation: - Lactobacillus rhamnosus GG - Lactobacillus helveticus R0052 - Bifidobacterium breve M-16V - Lactobacillus casei Shirota - Bifidobacterium infantis 35624 - Lactobacillus plantarum PS128 Thank you to our episode sponsor: Liver Medic Use code Chloe20 to save 20% on "Leaky Gut Repair" Brendan's YouTube Channel https://x.com/livermedic Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
Welcome back to our weekend Cabral HouseCall shows! This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track! Check out today's questions: Vikki: My son had kawasaki disease at 5yo. In hospital for week, got 2 IVIG treatments & high doses aspirin. Heart always looked good. Hes 16 & has been dealing w mild hearing loss& tinnitus, what can he do to lessen ringing or reverse? Assuming it was caused by the disease. Covid made it worse (no shot). Dizzy when it's at its worst. Avoids loud places, like movie theatre/church. Tried hearing aids but says didn't help. Healthy otherwise. Also what do you know about Kawasaki& future complications? TY Fiona: I have used your products to correct my autoimmune issues, thank you so much for helping me. My daughter is fighting a EBV infection and is so exhausted every day. She has just had an IV vitamin C treatment. She also has Enterococus Avium detected in stool. Bifidobacterium bifidium and breve, Lactobacillus plantarum, casei and acidophlis have low readings. What is the best protocol for her to follow please Jay: Hi Dr. Cabral I want to thank you and your team for all the work you do - it has been life changing for both me and my clients. I ran the big 5 did FM 21 detox, HMD, Ultimate sleep, Estrogen detox, and in the CBO protocol. I am wondering if you could tell me when I could retest to see improvement (looking to concieve - want to make sure everything is optimized). For reference I had low DHEA, high cortisol, estrogen dominance, + mercury, + aluminum candida, and oxalic acid. Patricia: Dear Dr. Cabral, thank you for all the information and knowledge you share, it has really made a difference in my life. This question is related to my father, he is 84 years old and recently diagnosed with skin cancer on different areas on his face,we believe it was caused to sun exposure and or chemicals due to his job when younger as a Petroleum Engineer working in the field. He has molds in his face and his back, some of those cancerous. One was recently removed from his tear duct cancerous. He is scheduled to have surgery soon for all the others found. Is there any recommendation you can give me on things that he can do before and after the procedure related to diet and supplements that can help him heal faster and prevent recurrencies? I value so much your opinion. Thank you so much Fernanda: I bought an EquiLife heavy metal detox kit for me and my husband and I just did your regular detox course online. Now I am wondering how these 2 compare. We don't want to lose weight as we are overall healthy already. We have completed three 5-day fasts using another product (Prolon) recently. How does a 5-day fast compare to EquiLife 7 day detox as far as removing toxins go? Will the removal of toxins in a 5-day water only or Prolon fast be compromised because there may not be enough amino acids to aid the phase 2 detox pathways? Should I do the regular detox before the heavy metal one? Please feel free to email me directly if that is not a question that you would like to answer on the podcast. FYI: I am also currently an IHP1 student and I bought 8 of the books you recommended so far. Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions! - - - Show Notes and Resources: StephenCabral.com/3032 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!
Dr. Elisa Song is one of those clinicians that I could just keep talking to! She's a respected colleague and pioneer in pediatric functional medicine with so many practical tips for navigating childhood illness and health. Need to get your kiddo/patient through a blood draw they don't want to do? Or get your picky eater to take their supplement? Dr. Song has the answers. I appreciate her candor as she talks about how and why her practice has evolved in certain areas (such as in the use of targeted probiotics and even "psychobiotics" for autism, ADHD, anxiety, OCD and more) and in spelling out which supplement brands and doses she uses and why. Dr. Song tackles the immense challenges impacting the health of our kids and teens head on with positivity and smart, doable strategies for lasting success. This is a fascinating and empowering discussion with many clinical pearls that I will be implementing both in practice and for my own daughter going forwards. I hope you enjoy it too! ~DrKF Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for all the relevant links and resources. Guest Information Dr. Elisa Song, MD Healthy Kids, Happy Kids: An Integrative Pediatrician's Guide to Whole Child Resilience: https://www.healthykidshappykids.com/book/ Healthy Kids, Happy Kids: https://healthykidshappykids.com/ IG: @healthykids_happykids FB: https://www.facebook.com/DrElisaSongMD/ Thank you to our sponsors Diamond Rupa Health: https://tinyurl.com/4anbz7b3 Biotics Research: https://www.bioticsresearch.com/ Integrative Therapeutics: https://tinyurl.com/4emwj48z Gold OneSkin: https://tinyurl.com/ycxtw4zt TimeLine Nutrition: https://tinyurl.com/bdzx2xms Midroll Practice Better: https://tinyurl.com/28mmab99 Start your free trial and save 20% for 4 months on any paid plan with code KF20 Show Notes A Potential Decline in Life Expectancy in the United States…https://tinyurl.com/3frr8z6d Lost microbes of COVID-19: Bifidobacterium… https://tinyurl.com/r348tm78 Increasing Prevalence of Antinuclear Antibodies… https://tinyurl.com/7why9yrv Role of Bifidobacteria on Infant Health: https://tinyurl.com/4sk5u9ds Protective effect of Bifidobacterium infantis CGMCC313-2 on… https://tinyurl.com/2kn2vjnw Trends in Consumption of Ultraprocessed Foods Among US Youths… https://tinyurl.com/5fn5sce7 Dietary patterns, brain morphology and cognitive performance in children…https://tinyurl.com/mp5ekp26
View Part 1 here: https://youtube.com/live/VCJdne9xgqgDr. Sabine Hazan returns to the Zone to discuss various aspects of the microbiome and its impact on health. During her conversation with Dr. Osborne, they explore topics such as fecal transplants, inflammatory bowel disease, and the differences in microbiomes between individuals.They also discuss the effects of cesarean section versus vaginal birth on the newborn's microbiome and the potential implications of imbalances in the overall microbiome of the planet. The conversation highlights the need for more research and funding in the field of microbiome studies. They discuss the potential benefits of fecal transplants for various conditions, including inflammatory bowel disease and autism.Some of Dr. Hazan's work discussed in this interview is posted below:Vitamin C improves gut Bifidobacteria in humans https://www.futuremedicine.com/doi/full/10.2217/fmb-2022-0209?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.orgDetection of SARS-CoV-2 from patient fecal samples by whole genome sequencing https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7846909/Microbiome-Based Hypothesis on Ivermectin's Mechanism in COVID-19: Ivermectin Feeds Bifidobacteria to Boost Immunity. https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/en/covidwho-1963494Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity. https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/en/covidwho-1816751Effectiveness of ivermectin-based multidrug therapy in severely hypoxic, ambulatory COVID-19 patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8826831/To connect with Dr. Osborne visit:On the web: https://drpeterosborne.com/ Facebook: https://www.facebook.com/DoctorPeterOsborne/Pinterest: https://www.pinterest.com/docosborne/Instagram: https://www.instagram.com/drosborneTwitter: https://twitter.com/glutenology*These statements have not been evaluated by the Food and Drug Administration. This video is not intended to diagnose, treat, cure or prevent any disease. It is strictly intended for educational purposes only. Additionally, this information is not intended to replace the advice of your physician. Dr. Peter Osborne is one of the most sought after alternative and nutritional experts in the world. A Diplomate with the American Clinical Board of Nutrition, a graduate of Texas Chiropractic College, and a doctor of pastoral science, Dr. Osborne is one of the world's leading authorities on gluten, nutrition, and natural health. He is the founder GlutenFreeSociety.org, one of the world's largest informational sites on gluten sensitivity. In addition, he is the author of the best selling book, No Grain No Pain, published by Touchstone (Simon & Schuster). His work has been featured by PBS, Netflix, Amazon, Fox, and many other nationally recognized outlets. For more information, visit us at https://www.glutenfreesociety.org/ or call 281-903-7527
View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman Sign Up for Dr. Hyman's Weekly Longevity Journal Every parent wants to raise a healthy kid, but our modern world, industrialized diet, and increased stressors can make that goal feel confusing and difficult. The good news is that we can do so many things during a child's life, and even before it starts, to give them the best possible chance to truly thrive in body and mind. I'm thrilled to share this in-depth conversation with pediatric Functional Medicine expert, and mom to 2 thriving children, Dr. Elisa Song. In this episode, we discuss: The disappearing act of Bifidobacterium infantis and why it matters Why preconception support is so important for optimal epigenetic programming The bloodwork Dr. Song runs when first assessing a child One nutrient that might dramatically help your sensory-sensitive child A grounded discussion around the controversial topic of vaccines And so much more! No matter how old your kids are, it's never too late to upgrade their health with holistic approaches. I know you'll love this episode as much as I did! This episode is brought to you by ButcherBox, Thrive Market, and One Skin. ButcherBox is giving new members two pounds of wild-caught salmon for FREE plus $20 off. Visit ButcherBox.com/Farmacy and use code FARMACY. Head over to ThriveMarket.com/Hyman today to received 30% off your first order and a free gift up to $60. Unlock your healthiest skin yet. Try OneSkin with 15% off your first purchase using code HYMAN15 at OneSkin.co today. Learn more about your ad choices. Visit megaphone.fm/adchoices
Today, I have the privilege of hosting Dr. Michael Roizen, a renowned expert in reversing and rebooting aging. His CV is extensive, you can read about him here. In 2007, Dr. Roizen was named Chief Wellness Officer at Cleveland Clinic, the first such position in a major healthcare institution in the United States. The concept might sound like something out of science fiction, but Dr. Roizen discussed real scientific endeavors aimed at reversing biological aging. He opened up about cutting-edge technologies such as 3D organ printing – which may one day allow us to replace aged organs with new ones – and research on telomeres and stem cells that are at the forefront of longevity studies.Key Takeaways:Reversing Biological Age: Dr. Roizen discusses how we can not only prevent but reverse our biological age through various methods.Future Innovations: A glimpse into future advancements such as 3D organ printing and breakthroughs in research that could allow us to reset our age back to our forties.Real Age Concept: An explanation of Real Age – an assessment tool that determines your body's health relative to your calendar age based on lifestyle choices. Take the Real Age test at ShareCare.com. Caveat. I took the test, which is long but multiple choice, and I knew based on some of the questions I was in trouble. The algorithm recommended that I don't eat enough whole grains--I eat almost none--or legumes, not good for my genetic profile, or fruit. I don't love fruit but do eat about two apples a week and berries or melon in season. It's pretty old school/western medicine oriented. I also got points off for not having a flu shot every year and never having had a pneumonia vax. Preventing Structural Change: Importance of avoiding severe structural damage now so you can benefit from potential future therapies.Health Parameters & Longevity Preparation: Insights into six parameters of health including diet, exercise, stress management (highlighted as most important), connection with others, and sleep quality.Metformin and Aging Debate: Discussion about Metformin's role in anti-aging; while it has been hyped up within certain circles, Dr. Roizen advises caution unless pre-diabetes or diabetes is present.Telomere Testing Accuracy Concerns: Skepticism around telomere length tests due to variability; emphasis on stem cell telomeres being more crucial than other cells' for longevity.Fasting Mimicking Diet (FMD): Explanation of Valter Luongo's FMD which resets genes allowing for increased stem cell growth upon resuming a normal diet after fasting periods.Supplements That Work: A brief mention at the end regarding supplements that may provide more benefits than risks according to Longevity.com's scientific advisory board evaluations - baby aspirin twice daily, CoQ10, probiotics like Bifidobacterium animalis ssp lactis HN019™️ , vitamin D above 50 ng/ml levels and half a multivitamin twice daily were highlighted among others.Dr. Roizen's latest book, he has written or co-authored numerous books, is
Today I am answering all of your supplement questions Q&A style. Join me as I dive into everything you need to know about the supplement industry. I answer questions concerning what supplements you should be taking and how to know how much to take. I also discuss getting nutrients from whole foods versus using protein powder. Based on research, we actually are not protein deficient. I talk about the science behind it and how to get the protein you need. I also go over probiotics and whole-food nutrition. Lactobacillus, Bifidobacterium, and Saccharomyces boulardii are the top three probiotic strains you should look for. Overall, this episode offers guidance on personal supplementation for health and longevity. Don't forget… You can order now by heading to https://darinolien.com/fatal-conveniences-book or order now on Amazon. Thank you to our sponsors: Vivo Barefoot: Get 15% off your first Vivobarefoot order with DARINV15 at www.vivobarefoot.com Find more from Darin: Website: https://darinolien.com/ Instagram: https://www.instagram.com/Darinolien/ Book: https://darinolien.com/fatal-conveniences-book/ Down to Earth: https://darinolien.com/down-to-earth/ Use code OLIEN20 for a Viome discount Candiani Denim: https://www.candianidenim.com/
In this revolutionary episode of the Gut Health Gurus Podcast, host Kriben Govender, a renowned Food Scientist and nutritionist, converses with Gut Microbiologist and Microbiome expert Dr Jelena Vulevic on Prebiotic supplementation (Beta GOS), and about her ground breaking research into delaying ageing and addressing hormonal and skin issues using novel postbiotic supplement based on Bifidobacteria breve.
The latest studies help inform how to resolve constipation, acid reflux, and food reactivity. If you're ready to nerd out about gut health, tune in. And if you have any other gut health topics you'd like me to cover, let me know in the comments! Watch/Read Next… Abdominal Self-Massage for Constipation: https://www.youtube.com/watch?v=zI4h_GXSJUk&t=2s Get Your Gut Moving: Probiotics for Constipation: https://drruscio.com/probiotics-for-constipation/ Choosing the Best Natural Laxative for Your Gut Problem: https://drruscio.com/natural-laxatives/ From Bloating to Reflux: Resolving Gastrointestinal Symptoms: https://drruscio.com/gastrointestinal-symptoms/ How to Identify and Treat Laryngopharyngeal Reflux (LPR): https://drruscio.com/laryngopharyngeal-reflux/ How to Reduce Stress-Induced Inflammation in 5 Simple Steps: https://drruscio.com/reduce-stress-inflammation/ How Being in Nature Reduces Stress and Improves Your Health: https://drruscio.com/nature-reduces-stress/ Why You Have Food Intolerances & How to Improve Them: https://www.youtube.com/watch?v=y-LNHKlk5Oc&t=212s Pelvic Floor Therapy: https://pelvicpainrehab.com/ Timestamps 00:00 Intro 01:22 Walking for constipation 02:29 Abdominal massage for constipation 06:20 Probiotics for regularity 09:32 Ginger for GI symptoms 11:49 Pelvic floor therapy 14:42 Gluten-free diet for acid reflux 15:53 FODMAPs for reflux 19:51 Fasting for reflux 20:38 Curcumin for reflux 22:39 Stress management for food reactivity 24:58 Zemedy App for food reactivity Featured Studies Exercise therapy in patients with constipation: https://pubmed.ncbi.nlm.nih.gov/30843436/ Analysis of the efficacy of abdominal massage on functional constipation: A meta-analysis: https://pubmed.ncbi.nlm.nih.gov/37496907/ Efficacy and safety of Bifidobacterium quadruple viable tablets combined with mosapride citrate in the treatment of constipation in China: https://pubmed.ncbi.nlm.nih.gov/37464298/ The effects of ginger supplementation on common gastrointestinal symptoms in patients with relapsing-remitting multiple sclerosis: https://pubmed.ncbi.nlm.nih.gov/37891539/ Biofeedback Treatment Can Improve Clinical Condition and Quality of Life in Patients with Pelvic Floor Dyssynergy with IBS: A Prospective Cohort Study: https://pubmed.ncbi.nlm.nih.gov/37547159/ Biofeedback therapy for constipation in adults: https://pubmed.ncbi.nlm.nih.gov/21382587/ Gluten Sensitivity Underlying Resistant "Laryngopharyngeal Reflux" Symptoms and Signs: https://pubmed.ncbi.nlm.nih.gov/37666745/ The Effect of FODMAP Meals on Transient Lower Esophageal Relaxations (TLESR) in Gastroesophageal Reflux Disease (GERD) Patients with Overlapping Irritable Bowel Syndrome (IBS): https://pubmed.ncbi.nlm.nih.gov/35565722/ The Impact of Intermittent Fasting on Patients With Suspected Gastroesophageal Reflux Disease: https://pubmed.ncbi.nlm.nih.gov/36730832/ The Role of Duodenal Inflammation in Functional Dyspepsia: https://pubmed.ncbi.nlm.nih.gov/27811629/ Psychological distress, perceived stress and nocebo effect (multifood adverse reaction) in IBS patients: https://pubmed.ncbi.nlm.nih.gov/37727431/ Meditation and Yoga for IBS: A Randomized Clinical Trial: https://pubmed.ncbi.nlm.nih.gov/36422517/ Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc Instagram - https://www.instagram.com/drrusciodc/ Pinterest - https://www.pinterest.com/drmichaelrusciodc DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
New research doesn't just tell us that probiotics improve leaky gut, candida, and IBS, it tells us how. Join me to unpack the exciting findings behind probiotics for leaky gut, candida, and IBS, and a protocol you can use at home to help find relief. And if you have any additional questions you would like answered in the future, let me know in the comments! Watch/Read Next… Create a Leaky Gut Diet Plan: https://drruscio.com/?p=56263 How to Spot Leaky Gut: https://www.youtube.com/watch?v=7QER7XXJ5CM&t=3s What's the Strongest Candida Killer?: https://drruscio.com/strongest-candida-killer/ What is IBS? https://drruscio.com/what-is-ibs How to Relieve the Symptoms of IBS Attacks: https://drruscio.com/stop-the-struggle-how-to-relieve-the-symptoms-of-ibs-attacks/ Timestamps 00:00 Intro 01:58 Impressive vaginal candida effectiveness 04:51 Gastrointestinal candida findings 05:56 Remarkable leaky gut results 10:04 Positive impacts to IBS symptoms 18:04 Where probiotics made no difference 19:58 Do different probiotics have different benefits? 22:46 The most effective probiotics for IBS 23:40 Research-based probiotic protocol Featured Studies Comparing the Effect of Probiotic and Fluconazole on Treatment and Recurrence of Vulvovaginal Candidiasis: a Triple-Blinded Randomized Controlled Trial: https://pubmed.ncbi.nlm.nih.gov/36198994/ Probiotics Prevent Candida Colonization and Invasive Fungal Sepsis in Preterm Neonates: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/27793494/ Candida albicans- The Virulence Factors and Clinical Manifestations of Infection: https://pubmed.ncbi.nlm.nih.gov/33499276/ Effect of a Multistrain Probiotic on Leaky Gut in Patients with Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study: https://pubmed.ncbi.nlm.nih.gov/36007493/ Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials: https://pubmed.ncbi.nlm.nih.gov/37168869/ An 8-Week Course of Bifidobacterium longum 35624® Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome: https://pubmed.ncbi.nlm.nih.gov/37702965/ Efficacy and dose response of Lactiplantibacillus plantarum in diarrhea-predominant irritable bowel syndrome: https://pubmed.ncbi.nlm.nih.gov/37576702/ Efficacy and safety of Bifidobacterium quadruple viable tablets combined with mosapride citrate in the treatment of constipation in China: a systematic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/37464298/ Evaluation of the effects of the FODMAP diet and probiotics on irritable bowel syndrome (IBS) symptoms, quality of life and depression in women with IBS: https://pubmed.ncbi.nlm.nih.gov/37430435/ The Efficacy and Safety of Single-Strain Probiotic Formulations Containing Bifidobacterium lactis or Bacillus coagulans in Adult Patients with Irritable Bowel Syndrome-A Randomized Double-Blind Placebo-Controlled Three-Arm Interventional Trial: https://pubmed.ncbi.nlm.nih.gov/37510953/ Outcome-Specific Efficacy of Different Probiotic Strains and Mixtures in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis: https://pubmed.ncbi.nlm.nih.gov/37686889/ Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc Instagram - https://www.instagram.com/drrusciodc/ Pinterest - https://www.pinterest.com/drmichaelrusciodc DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video. Click here to apply for our YouTube Channel & Podcast Manager position. https://drruscio.bamboohr.com/careers/71?source=aWQ9MjE%3D
Supplements to help you fall asleep are a big topic, and there are many to choose from, but these are my favorite supplements to get you to sleep faster. GENETIC ROCKSTARS (an MTHFR community): community.tohealthwiththat.com FREE COURSE: MTHFR Basics: https://courses.tohealthwiththat.com/p/mthfr-basics WORK WITH DR. AMY ONE-ON-ONE: Set up a free meet and greet appointment to see if we're a good fit to work together, or if group coaching, community, or something else might be a better option: https://calendly.com/amy-tohealthwiththat/15min GROUP COACHING: go.tohealthwiththat.com/watch-the-free-videoWEBSITE: https://tohealthwiththat.com/ AFFILIATE LINKS: I get a small profit when you choose to buy from these links, so thank you! SEEKING HEALTH (methylation and histamine support supplements - these ship internationally): https://bit.ly/3afXYH4 STRATEGENE REPORT (detailed genetics using 23andme or ancestry raw data): https://bit.ly/3retbm5 FULLSCRIPT (professional grade supplements): https://us.fullscript.com/welcome/thwt QUEEN OF THE THRONE (castor oil and castor oil packs): https://shop.queenofthethrones.com/amy-tohealthwiththat use code AMY_TOHEALTHWITHTHAT10 for 10% off of any order of $59 or more 00:00 - Intro 00:49 - Make sure you're not taking something that keeps you awake 01:13 - Special precaution with MTHFR 01:57 - Body won't relax 02:28 - Magnesium 03:15 - Opposite reaction to magnesium 03:30 - GABA 03:57 - Passionflower 04:15 - Agitated mind 04:34 - Valerian Root 04:58 - Bifidobacterium longum 1714 05:42 - Aromatherapy 06:23 - Chamomile 06:58 - Glycine 07:25 - Melatonin 09:18 - Next episode --- Send in a voice message: https://podcasters.spotify.com/pod/show/tohealthwiththat/message
Recent research highlights that probiotics can make a significant impact on a wide range of conditions like immunity, stress, allergies, and even lactose intolerance. Tune in to hear the latest updates and stay in step with the science. Read & Watch Next What is Leaky Gut? https://drruscio.com/what-is-leaky-gut/ How to Use Probiotics for Bloating & Constipation Relief: https://drruscio.com/probiotics-for-bloating/ How Long Does it Take for Probiotics to Work? https://drruscio.com/how-long-does-it-take-for-probiotics-to-work/ 7 Surprising Things That are Stressing Your Nervous System: https://drruscio.com/things-stressing-your-nervous-system/ The Latest Research Update Episodes: https://drruscio.com/research-updates/ Why You Have Food Intolerances & How to Improve Them: https://www.youtube.com/watch?v=y-LNHKlk5Oc&t=14s Timestamps 00:00 Intro 00:56 Benefits for white blood cells 04:11 Benefits for diarrhea & sickness duration 08:13 Benefits for the stress response 13:21 Benefits for food allergies 19:22 Research update wrap-up Featured Studies Effect of synbiotic supplementation on immune parameters and gut microbiota in healthy adults: a double-blind randomized controlled trial: https://pubmed.ncbi.nlm.nih.gov/37614109/ Adjunctive efficacy of Lactis XLTG11 for Acute diarrhea in children: A randomized, blinded, placebo-controlled study: https://pubmed.ncbi.nlm.nih.gov/37172455/ The effect of oral probiotics on CD4 count in patients with HIV infection undergoing treatment with ART who have had an immunological failure: https://pubmed.ncbi.nlm.nih.gov/37382253/ Effects of Heat-Killed Lacticaseibacillus paracasei MCC1849 on the Maintenance of Physical Condition in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study: https://pubmed.ncbi.nlm.nih.gov/37571384/ Potential probiotics for regulation of the gut-lung axis to prevent or alleviate influenza in vulnerable populations: https://pubmed.ncbi.nlm.nih.gov/36970463/ Bifidobacterium longum subsp. longum Reduces Perceived Psychological Stress in Healthy Adults: An Exploratory Clinical Trial: https://pubmed.ncbi.nlm.nih.gov/37513541/ Intake of Lactiplantibacillus plantarum HEAL9 Improves Cognition in Moderately Stressed Subjects: A Randomized Controlled Study: https://pubmed.ncbi.nlm.nih.gov/37571403/ Exaggerated amygdala response to threat and association with immune hyperactivity in depression: https://pubmed.ncbi.nlm.nih.gov/35636614/ Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials: https://pubmed.ncbi.nlm.nih.gov/37168869/ The role of probiotic supplementation in inflammatory biomarkers in adults: an umbrella meta-analysis of randomized controlled trials: https://pubmed.ncbi.nlm.nih.gov/37698776/ Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome: https://pubmed.ncbi.nlm.nih.gov/28483500/ Lacticaseibacillus rhamnosus HA-114 improves eating behaviors and mood-related factors in adults with overweight during weight loss: a randomized controlled trial: https://pubmed.ncbi.nlm.nih.gov/35714163/ The Effectiveness of Probiotics in Treating Food and Cow's Milk Allergies among Pediatric Age Group: A Meta-analysis of Randomized Controlled Trials: https://pubmed.ncbi.nlm.nih.gov/37496406/ Effects of probiotics administration on lactose intolerance in adulthood: A meta-analysis: https://pubmed.ncbi.nlm.nih.gov/37225575/ Get the Latest Updates Facebook - https://www.facebook.com/DrRusciodc Instagram - https://www.instagram.com/drrusciodc/ Pinterest - https://www.pinterest.com/drmichaelrusciodc DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment. Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g *Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
Dans ce nouvel épisode de podcast, nous recevons Marjolaine Cadieux, nutritionniste. Découvre son parcours, ses valeurs et explore l'alimentation intuitive. Marjolaine partage son expertise sur la santé intestinale, les signes d'équilibre, et offre des conseils. La discussion devient plus personnelle avec son témoignage sur son trouble du comportement alimentaire, abordant les signes, le soutien et sensibilisant sur le sujet. Merci à Marjolaine pour cette exploration concise et enrichissante de l'alimentation et de la santé. Marjolaine répond également aux questions de la communauté, elle traite des commentaires sur le poids, du live food et du jeûne intermittent. La conversation se clôture sur une note inspirante avec une anecdote Harry Potter. ★ Rabais GIRL CRUSH : EPSVP15 pour 15% de rabais sur votre commande : https://girlcrushgang.com/ (Pssssst : Les membres agents secrets ont le droit à 20% de rabais!) ★ Pour suivre Marjolaine : https://www.instagram.com/lespiedsdanslesplats_/ ★ Cet épisode est présenté par Squarespace : obtiens 10% de rabais sur ta commande avec le code LUCIER ! ★ Cet épisode est créé en partenariat avec Activia, une marque engagée à aider les femmes à prendre soin de leur bien être*. La gamme variée de yogourts probiotiques* Activia s'adapte à tous les styles de vie et moments de la journée. Découvrez en plus en écoutant l'épisode pour intégrer les bienfaits des yogourts Activia dans votre quotidien! * Les yogourts probiotiques d'Activia contiennent plus de 109 UFC de Bifidobacterium lactis par portion, un probiotique contribuant à la santé de la flore intestinale.____________________Pour suivre le podcast sur Instagram: https://www.instagram.com/enprivesvp/Pour suivre le podcast sur Tiktok : https://www.tiktok.com/@enprivesvpPour des demandes de partenariats ou pour louer le studio d'enregistrement : project@girlcrushgang.comPour suivre Cindy: https://www.instagram.com/cindycourno...Pour suivre Lucie: https://www.instagram.com/lucierheaume/ ENGLISH VERSIONIn this new podcast episode, we welcome nutritionist Marjolaine Cadieux. Discover her background, her values and explore intuitive eating with her. Marjolaine shares her expertise on gut health, probiotics and offers her advice. The discussion gets personal with Marjolaine sharing her eating disorder story and raising awareness on the subject. Thanks to Marjolaine for this concise and enriching exploration of food and health. This episode is created in partnership with Activia, a brand committed to helping women take care of their overall well-being*. Activia's various range of probiotic* yogurts is suitable for every lifestyle and times of the day. Listen to the podcast episode to find out more on how to integrate the benefits of Activia yogurts into your daily routine! * Activia probiotic yogurts contain more than 109 CFU Bifidobacterium lactis per serving, a probiotic that contributes to healthy gut flora.Pour de l'information concernant l'utilisation de vos données personnelles - https://omnystudio.com/policies/listener/fr
Welcome to our podcast on "The Science Behind The Oral Health Probiotic from Bristle Health." In today's episode, we explore the research and clinical studies backing Bristle's unique oral probiotic formulation. Join us as we uncover and discuss how these probiotics revolutionize oral healthcare by balancing the oral microbiome, the specific strains used in this product, the benefits they offer and how they combat common dental issues. Key Takeaways:-Innovative Approach: Bristle's Oral Health Probiotic represents a cutting-edge approach in oral healthcare, focusing on balancing the oral microbiome for better overall oral health.-Six Key Strains: The product contains six clinically proven probiotic strains - Streptococcus salivarius M18, Streptococcus salivarius K12, Lactobacillus reuteri, Lactobacillus salivarius, Lactobacillus plantarum, and Bifidobacterium lactis - each with a specific role in improving oral health.-Clinical Backing: Each strain included in the probiotic has been backed by clinical studies and research, demonstrating their efficacy in reducing gum inflammation, combatting tooth decay, and fighting bad breath.-Natural and Safe Ingredients: The probiotic is made with natural ingredients, including xylitol instead of sugar, making it a safer and more effective option for oral health maintenance.-Usage Recommendations: For best results, the probiotic should be used once daily for general oral health maintenance and twice daily for addressing specific oral health issues like gum disease and bad breath.Book a consultation today:I am always here to help answer any question and schedule a 15 minute call with me. If I can not help, I can get you to a provider that can.https://shereewertz.com/15-min References:Journal of Applied Microbiology: “A preliminary study of the effect of probiotic Streptococcus salivarius K12 on oral malodour parameters.”Journal of Breath Research: “Oral probiotics reduce halitosis in patients wearing orthodontic braces: a randomized, triple-blind, placebo-controlled trial.”Journal of Oral Microbiology: “Effect of the probiotic Lactobacilli reuteri (Prodentis) in the management of periodontal disease: a preliminary randomized clinical trial.”BMC Oral Health: “Effects of Lactobacillus salivarius-containing tablets on caries risk factors: a randomized open-label clinical trial.”Journal of Clinical Periodontology: “Clinical and microbiological effects of the adjunctive use of probiotics in the treatment of gingivitis.”
Last week, we discussed the potential for semaglutide to cause diarrhea and ways to help get relief. Today I want to talk about how semaglutide can cause constipation and everything you should know to manage your semaglutide-related constipation. Why does semaglutide cause constipation? Constipation can happen with semaglutide, but it tends to be less common than diarrhea. Up to 12% of people taking it for type 2 diabetes and 24% of people taking it for weight loss reported constipation in clinical trials. Understanding the causes of constipation from semaglutide and learning how to manage it is important for people using it. Like diarrhea, you're more likely to experience constipation with higher doses of semaglutide, and the good news is that this side effect usually goes away over time as your body gets used to the medication. It's not exactly clear why semaglutide causes constipation, but research suggests that it has to do with how the medication works. Because semaglutide slows down how fast food leaves your stomach, people feel fuller longer and tend to eat and drink less. Not getting enough fluid can cause constipation because there is less liquid in the stool, making it harder for you to have a bowel movement. Semaglutide also causes your pancreas to release insulin, which lowers your blood glucose (sugar) and helps your cells use glucose from the food you've eaten. This is helpful because extra glucose your cells don't use is stored as fat, which is why high blood sugar can lead to weight gain. But keep in mind that insulin also slows down your gut, which means you may have a bowel movement less often. How do you manage constipation from semaglutide? Dietary Changes: Add more fiber-rich foods like whole fruits (raspberries, apples, and bananas) and vegetables like broccoli, sweet potato, and lentils. It's recommended to start with 2 servings per day. Most adults should aim for 25 to 30 grams or more every day. You'll want to start slow because eating too much fiber can have the opposite effect and cause bloating, gassiness, and more constipation. Stay active: Reduced physical activity can lead to constipation. Moving around can help get things moving in your gut and also relieve bloating. Try to get at least 15 minutes of physical activity during the day to help get your bowels moving. Stay hydrated: Like diarrhea, constipation can happen if you're dehydrated. Drinking water and clear fluids will help prevent your stools from becoming hard and dry. You can also try using the bathroom at the same time each day and make sure not to hold your poop in when you have to use the bathroom. This will help your gut get into a good rhythm. It's recommended to take your bathroom breaks about 30 minutes after you eat. This is when your gut is most active. Over-the-counter (OTC) Remedies: Over-the-counter fiber supplements, laxatives, or stool softeners can be used to manage constipation. These products can help soften stools and make them easier to pass. Popular products include Dulcolax (laxative), Colace (stool softener), and Metamucil (fiber supplement). Probiotics: Probiotic supplements or probiotic-rich foods like yogurt, kefir, and fermented vegetables can help regulate gut health and promote regular bowel movements. Probiotics contain beneficial bacteria that support the natural balance of the digestive system. Popular probiotics are Lactobacillus and Bifidobacterium. Make sure to keep track of your constipation symptoms, including the frequency of bowel movements and any discomfort. This information can be valuable for your healthcare provider in adjusting your treatment plan. And let your provider know if you are unable to eat, have stomach pain, and experience vomiting. Thanks again for listening to The Peptide Podcast, we love having you as part of our community. If you love this podcast, please share it with your friends and family on social media, and have a happy, healthy week! Pro Tips We're huge advocates of using daily greens in your routine to help with gut, skin, nail, bone, and joint health. We take AG1 (athletic greens) every day. Not only does it have vitamins, minerals, and a diverse range of whole-food sourced ingredients, but it also has probiotics to promote a healthy gut microbiome and adaptogens to help with focus and mood balance. It's vegan, paleo, and keto-friendly.
Should you take supplements for IBS? In particular probiotics, prebiotics or digestive aids. There are certainly plenty advertised online, or promoted by social media influencers. But who can you trust? And are they worth the money? In this episode I'll share my thoughts on gut health supplements so you don't have to spend any longer searching online for the next best gut health hack. I'm sharing things I use with my Gut Reset clients, things that I know work, and I'll explain how you should take them, and how you will know if they're working. I coverProbioticsDigestive enzymesSaccharomyces BoullardiiDigestive bittersPHGGStrains for ConstipationLowering methaneLactobacillus reuteri DSM 17938Increase bowel movement frequencyBifidobacterium lactis BB-12Lactobacillus rhamnosus (best with FOS)Improving transit time - Bifidobacterium lactis HN019Bifidobacterium animalis subsp. lactis DN-173 010Strains for bloatingLactobacillus acidophilus NCFM® Bifidobacterium lactis HN019Bifidobacterium lactis Bi-07®Lactobacillus plantarum Lp299vBifidobacterium infantis 35624Bacillus CoagulansSaccharomyces cerevisiae CNCM I-38561Lactobacillus acidophilus Rosell-52Website - www.goodnessme-nutrition.com
Hey there, welcome back to the Empowered Nutrition Podcast. I'm Erin Skinner, your host, and I'm excited to take you on a journey into the incredible world of Berberine in this episode. Together, we'll discover the superpowers of this natural plant compound and its profound impact on our digestive, metabolic, and hormonal health. Berberine: The Unsung Hero Imagine Berberine as the unsung hero of the supplement world. It's not a prescription drug, but it's gaining superstar status for its unique ability to kickstart the release of glucagon-like peptide-1 (GLP-1). These GLP-1 superpowers are a game-changer in the realm of metabolic health. Safety First: Navigating the Berberine Universe Let's navigate the safety of Berberine. Most adults can embrace its benefits, but we need to be cautious. Expect some minor side effects like mild abdominal discomfort, constipation, or the occasional bout of nausea. But a word of advice, Berberine is best suited for those facing health challenges. For healthy individuals, it may not be the supplement you're looking for. Witness Berberine's Breathtaking Feats Prepare to be wowed by Berberine's breathtaking feats. It swoops in to save the day in the battle against diabetes, polycystic ovary syndrome (PCOS), high cholesterol, and the formidable obesity villain. It's a powerful ally, but having healthcare professionals as your sidekicks when introducing Berberine to your health journey is a smart move. Dosing Drama and Cautious Calm Let's dive into the dosing drama. The script reads 500 milligrams, two to three times a day, for one to six months. Berberine may be a powerful ally, but long-term alliances should be approached with caution. Especially if your medication squad is already on standby. Berberine's Secret Weapons Discover Berberine's secret weapons as I unravel the six primary mechanisms through which it conquers the battlefield. From rallying nitrate-reducing bacteria to amping up short-chain fatty acid production, this hero doesn't back down. It's all part of the grand plan to reduce inflammation, optimize bile metabolism, foster Akkermansia bacteria growth, and control hormones to slay the dragons of appetite and sugar cravings. Calling All Health Warriors Berberine steps into the spotlight when health warriors face particular adversaries. When weight loss resistance, metabolic syndrome, insulin resistance, type 2 diabetes, and PCOS are the battlegrounds, Berberine is your trusty sword. For other quests, consult your healthcare professionals for guidance. Enduring Legacy The awe-inspiring aspect of Berberine? Its enduring legacy. Even after Berberine exits the stage, its impact on the gut microbiome continues to shine. It's like having a guardian angel looking out for your health, long after the final bow. The Final Act As we wrap up this episode, I hope you've gained a newfound appreciation for the superpowers of Berberine. This superhero in supplement form may be your ticket to a healthier, happier future. References used in this podcast episode: 1.The Natural Medicine's Database: Berberine (Professional Monograph) https://info.trchealthcare.com/natmed-ppc 2.Zhang Y, Gu Y, Ren H, et al. Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study). Nat Commun. 2020;11(1):5015. 3.Habtemariam S. Berberine pharmacology and the gut microbiota: A hidden therapeutic link. Pharmacol Res. 2020;155:104722. 4.Zhang L, Wu X, Yang R, et al. Effects of Berberine on the Gastrointestinal Microbiota. Front Cell Infect Microbiol. 2020;10:588517. 5.Och A, Och M, Nowak R, Podgorska D, Podgorski R. Berberine, a Herbal Metabolite in the Metabolic Syndrome: The Risk Factors, Course, and Consequences of the Disease. Molecules. 2022;27(4). 6.Cao RY, Zheng Y, Zhang Y, et al. Berberine on the Prevention and Management of Cardiometabolic Disease: Clinical Applications and Mechanisms of Action. Am J Chin Med. 2021;49(7):1645-1666. 7.Wang H, Zhang H, Gao Z, Zhang Q, Gu C. The mechanism of berberine alleviating metabolic disorder based on gut microbiome. Front Cell Infect Microbiol. 2022;12:854885. 8.Li J, Meng P, Zhang J, He M. Effect of Berberine Hydrochloride on the Diversity of Intestinal Flora in Parkinson's Disease Patients. Contrast Media Mol Imaging. 2022;2022:8381870. 9.Ming J, Yu X, Xu X, et al. Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study. Genome Med. 2021;13(1):125. Ready to dive in? Listen here! Love it? Hate it? We'd love to hear your feedback! Interested in our Lean for Life Membership? Heal your Metabolism with the Lean for Life app: https://empowered-nutrition.ck.page/193bb2cd67 Help yourself feel aligned using our three phase approach: Lean for Life Membership called Heal, Optimize , and Refinewhere you will be empowered to reverse previous metabolic damage with the assistance of our team of Registered Dietitian Nutritionists. Check out more details on our website! Want to learn more about our one-on-one Empowered Nutrition coaching? Book a free chemistry call to discuss your story and see if we're a good fit. Enjoying the podcast? Please review the Empowered Nutrition Podcast on Apple Podcasts or wherever you listen! Then, send me a screenshot of your positive review to podcast@empowerednutrition.health as a DM on Instagram (@empowerednutrition.health).Include a brief description of what you're working on with your health and/or nutrition and I'll send you a free custom meal plan! Do you have questions you would like answered on the Empowered Nutrition podcast? 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Welcome to another episode of The Synthesis of Wellness Podcast! Today, we are talking all about my latest n=1 experiment: using the FlexBeam (a red and infrared light therapy device) on my gut microbiome. Then, we transition into cosmetic peptides with an emphasis on TB-500 for stimulating and accelerating hair growth! Thanks so much for tuning in! Topics: 1. Introduction - Biohacking congress in Miami - Invitation to connect with me for meet-ups and ticket discounts 2. Red and Infrared Light Therapy - Introduction to the red light and infrared therapy device (FlexBeam) - Description of the device's features and capabilities - Explanation of its ability to penetrate up to 10cm within the body - Interest in exploring the impact of red and near-infrared light on the gut microbiome - Self-experiment! 3. Scientific Context - Definition of Photobiomodulation and its healing properties - Mention of studies exploring the effects of light therapy on the gut microbiome - Discussion of the impact of Photobiomodulation on gut microbial diversity 4. Human Microbiome Studies** - Mention of preliminary unpublished work using Photobiomodulation on the human microbiome - Increases in Akkermansia muciniphila, Bifidobacterium sp., and Faecalibacterium sp. - Impact on the Firmicutes:Bacteroides ratio as an indicator of gut health 5. Personal Experiment - Experiment using the FlexBeam device with both red and infrared light - Explanation of the wavelengths used in the experiment - Description of the experiment's frequency and duration - Excitement about the potential results and anecdotal observations 6. Transition to Cosmetic Peptides - Introduction to the topic of cosmetic peptides - Focus on thymosin beta-4 and its various uses 7. Thymosin Beta-4 for Hair Growth - Background information on thymosin beta-4 - Discussion of the hair follicle structure and growth cycle - Explanation of the anagen, catagen, and telogen phases - Role of stem cells in the bulge area during anagen phase - Overview of the acceleration of stem cell migration due to thymosin beta-4 8. Stem Cell Migration and Hair Growth - Significance of stem cell migration in hair follicle growth - Natural expression of thymosin beta 4 during anagen phase - Migration of cells from the bulge to the bulb region 9. Effectiveness and Administration - Discussion on the effectiveness of thymosin beta-4 for hair growth - Mention of a study using topical thymosin beta-4 on shaved rats - Role of angiogenesis in promoting blood flow to the scalp - Connection between inflammation and decreased blood flow 10. Application Methods - Topical application in most studies - Mention of subcutaneous injections for broader repair/regeneration - Emphasis on working with licensed physicians 11. Conclusion - Acknowledgment of individual variability in hair growth approaches - Reminder of the importance of addressing root causes of hair loss Thanks so much for tuning in! If you liked this episode, please leave a rating and review or share it to your stories over on Instagram. If you tag @synthesisofwellness, Chloe would love to personally thank you for listening! Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! Or visit linktr.ee/synthesisofwellness to see all of Chloe's links, schedule a BioPhotonic Scanner consult with Chloe, or support the show! Thanks again for tuning in! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
En la intersección de la biología y la psicología, nos encontramos con un concepto transformador: los psicobióticos. Una revolución en la comprensión de cómo la microbiota intestinal puede cambiar el panorama de la salud mental. Descubre cómo estos probióticos específicos, desde Lactobacillus helveticus hasta Bifidobacterium longum, están redefiniendo lo que sabíamos sobre el cerebro, el intestino y la conexión entre ambos. El inicio de una nueva era de bienestar mental y físico. Si siempre has buscado innovar en tu salud y bienestar, este es el momento. Desde los aminoacidos de cadena corta, a los neurotrasnmisores como GABA y serotonina, como el eje microbiota intestino cerebro, la comunicación que existe entre nuestro sistema nervioso y los microorganismos que nos habitan es maravillosa. En este viaje de descubrimiento, cuestiona lo establecido y reinventa tu percepción de salud desde el interior. Es el momento de pensar diferente sobre nuestra salud mental y bienestar. No olvides suscribirte a nuestro canal para más descubrimientos impactantes. ❤️Puedes apoyar este proyecto de divulgación en
In this episode of the Smarter Not Harder Podcast, our guest Dr. Kiran Krishnan joins our host Dr. Ted Achacoso to give one-cent solutions to life's $64,000 questions that include: What are the most exciting clinical developments in the field of gut microbiota and probiotic supplementation? How do outer membrane vesicles violate the dogma that bacteria and human cells should not communicate directly? Why is the gut microbiota now considered an organ in the body that is postnatal, or an organ that grows right after birth? Kiran Krishnan is a Research Microbiologist and has been involved in the dietary supplement and nutrition market for the past 17 years. He comes from a strict research background having spent several years with hands-on R&D in the fields of molecular medicine and microbiology at the University of Iowa. He left University research to take a position as the U.S. Business Development and Product Development lead for Amano Enzyme, USA. Amano is one of the world's largest suppliers of therapeutic enzymes used in the dietary supplement and pharmaceutical industries in North America. Kiran also established a Clinical Research Organization where he designed and conducted dozens of human clinical trials in human nutrition. What we discuss: (0:00:04) - Gut microbiota and probiotics revolution (0:17:21) - Gut microbiota and organ function (0:25:30) - Bifidobacterium longum's impact on mood (0:31:22) - Gut bacteria and brain development (0:45:55) - Microbiome and covid-19 risk factors (0:51:41) - Inter-kingdom communication and implications (1:12:09) - Probiotics' impact on inflammation and microbiome (1:17:19) - Microbiome analysis in clinical trials (1:24:02) - Microbiome's role in addiction and autoimmunity (1:37:30) - Microbiome functionality and redundancy (1:42:10) - Foundational organisms and future projects (1:55:10) - Advancing phytoceuticals and extraction processes (2:11:47) - Advancements in gut microbiota science Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more from Dr. Kiran Krishnan: Instagram: @kiranbiome Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.
In today's episode we're going to be talking about the gut microbiome. Why it's important, how to know what's going on with your microbiome and how to optimize it. The microbiome consists of microbes that are both helpful and potentially harmful for us and our bodies. Most of these organisms are symbiotic, meaning they and us benefit at the same time, but some are pathogenic, which are those that cause trouble, produce toxins, and increase inflammation. When we are healthy, both symbiotic and pathogenic microorganisms coexist without problems in a perfect balance and without causing us to get sick. The problem comes when this perfect balance is disrupted, causing our metabolic and immune function to be negatively affected. That's why it is so important to identify and to get your microbiome back on track. Today we will focus mainly on the gut biome, although it is now well known that it is important to have a healthy balance of microbes in all different areas of our bodies, including the skin and vagina. They all relate back to the gut, so let's focus there. What Is the Gut Microbiome? I'm thinking that a lot of you probably have heard about the gut microbiome, also known as the biome or the gut microbiota. Essentially, it's referring to the microorganisms that are living in our digestive tract. This group of microbes living inside of us fluctuate on a daily, weekly and monthly basis based on our diet, physical activity, medications we take, toxins exposure and stress exposure. The important thing here is to try to have a healthy balance of this microbes as much as possible. When there's a healthy balance, the good bacteria counterbalance the potentially harmful bacteria. When our microbiome gets out of balance, it's either that there are not enough good bacteria, or too much of the potentially harmful bacteria. And that's when health issues start. Research is showing that if the gut microbiome gets out of balance, it can increase the risk of many health issues including infections (bacterial, yeast, and viral), autoimmunity conditions, metabolic disorders, even weight gain, anxiety, depression, menstrual irregularities, PCOS, endometriosis, fertility issues, osteoporosis, kidney diseases, heart disease, diabetes, and dementia. Having a healthy balance of microbes in the gut is essential for our health. What Is This Gut Microbiome Doing for Us? As you might suspect from the various health issues that I just mentioned, the microbiome communicates and supports our immune system and help protect us from infections and autoimmunity (which is when our immune system gets confused and starts trying to protect us from our own self) so, by having a good balance of microbes in your gut, you're helping your immune system stay on track and protect you. These microbes also communicate with our nervous system via the Vagus nerve and other mechanisms. These guys are sending messages to our brain and our nervous system, they're communicating about what's happening down in our gut, they can cause us to crave some kinds of foods in order to feed them. They can affect our mood, our memory and our focus. They also make certain nutrients like B vitamins (including activating B12), vitamin K and short chain fatty acids (which are protective to the colon). Furthermore, they participate in making neurotransmitters such as GABA and can influence the production of serotonin and dopamine in our nervous system. What we're learning from research is that they help us recover from stress and toxin exposure! As you know I specialize in how humans are affected by stress and what we can do to recover from stress, and so I would say that optimizing the microbiome has a huge impact on our stress recovery. How Do We Maintain a Healthy Microbiome? So, we now know they're important, but how do we take care of them? It's like having a pet, you must know how to feed them and how to take care of them so that they can be healthy. What we eat is what feeds our gut bacteria. Of course, they're living in our gut so what we swallow is going to influence them and what's going to feed them potentially. Our gut bacteria can ferment foods what we as humans are unable to digest, like fiber or complex starches for example. They can ferment fruits, vegetables, grains, nuts, seeds. Foods and fibers that feed our microbiome are called “prebiotics.” Fructooligosaccharides in garlic, onions, leeks, asparagus, artichokes, kale, dandelion, as well as bananas, contain the highest amount of prebiotics, or super food, for our gut bacteria. It's important to know that it's possible to over feed your gut bacteria! In fact, I would say that it is much more likely to overfeed your bacteria than to underfeed them. I see a higher percentage of patients with overgrowing bacteria rather than with too few bacteria. Going back to the pet analogy, we have to know how to feed our gut bacteria correctly. Symptoms of overfeeding your gut bacteria include bloating, gas, cramping, bowel changes, weight gain, and burping. Consuming prebiotics in excess or eating too much fermented foods (yoghurt, sauerkraut, kimchi, miso, kombucha, etc.) can cause overgrowth. We want that optimal amount and balance of good and bad gut bacteria, so just be aware and cautious and listen to your body. If you are consuming a lot of prebiotics, high fiber foods, fermented foods and you start to feel bloated or have bowel changes or gas, or even if you have infections (sinus, bladder, vaginal) or joint pain, inflammation, headaches, skin rashes, these are all symptoms that you may be overfeeding your gut bacteria. How Can You Know if You're Overfeeding Your Gut Microbiome? What you can do is a stool analysis. For many years we have had stool cultures. The culture is when you send in a stool sample into the lab and they allow it to grow over several days. The problem with cultures is that some bacteria are anaerobic, so they don't grow in a lab environment. Then, about a decade ago, they came out with a DNA analysis of the gut bacteria. This is DNA sequencing so no matter whether the bacteria are alive or not, they can identify them based on their DNA. This is a much more accurate way of knowing which bacteria are thriving, or overgrowing, in your microbiome. There are now consumer versions of these stool tests that you can order online and send in your stool sample. They may make suggestions in terms of how to change your diet to feed the bacteria that are too low, and not overfeed those that are too high. It's important to consider that, while making certain diet changes can help, I have not found that decreasing or increasing specific foods is an effective solution to adjust your microbiome (and I have tried it with hundreds of patients). That is because many of the same foods that feed the good bacteria, also feed the bad bacteria. It doesn't work to manipulate your diet, in terms of eating specific fruits or seeds, in order to make minor adjustments in your biome. A much better approach is to choose a variety of foods in your diet. If you're eating the exact same foods every day, it is more likely to cause an overgrown of bacteria (or yeast). In that case, increasing the variety in your diet and eating other kinds of fruits, vegetables, nuts and seeds each day, or alternating through the week, will help to improve the diversity of bacteria because you'll be feeding a greater number of types overall. When it comes to our gut microbiome, we want diversity. There are over 1,000 bacterial species that have been identified with about 160 species being found living in the gut of any individual so we don't want to just feed certain ones. Now, if your gut microbiome is really needing more help and you have symptoms of overgrowing bacteria, or a health issue related to the gut biome, then some additional steps need to be taken. There is a clinical stool panel called the GI MAP that I find has helped so many of my patients by showing exactly which bacteria, yeast, protozoa and/or parasites are present, so we can tailor a specific protocol to address them. I can order this test through my office for you and then we can see who's living there in your gut. It will also tell us if there is inflammation (calprotectin) or antigliadin antibodies, and how well are you digesting your food. We can see quite a lot about your digestive system in this type of clinical stool panel, and from there I can get way more specific and design a strategy for you so we can get your biome back on track. What Can We Do to Rebalance Our Gut Bacteria? When we're constantly under stress, we don't digest our food well, and this will cause an imbalance in the gut bacteria, let alone many potential health issues. If our food is not digested well, we're not going to be able to absorb the nutrients, so it's not going to feed us, and instead it's going to overfeed the bacteria and other microbes. So, how do we support our digestion? Well, we can start by taking the time to slow down and consciously eat. Take your time and sit down, breathe, chew well, etc. This way you are sending signals to your Vagus nerve communicating that it's time to make enzymes and digest. You can also take pancreatic enzymes if needed to help you digest food while your system is healing. This is something that will show on the stool panel. Also, if you're not making enough bile, we can support bile production for fat digestion. If you're not making enough stomach acid (hydrochloric acid) we can add that to help with protein digestion. We can support the digestion of your food in many different ways, including herbs that stimulate digestion or even just eating plants that are bitter (like arugula), which help with digestion. If there's overgrowing pathogenic bacteria, referred to as “dysbiosis,” I would guide you through a protocol of using antimicrobial herbs that are effective at addressing the bacteria that are overgrowing, without wiping out all your good bacteria. That's a very specific protocol that I developed and tested over the years and one that works for the majority of patients. In addition to antimicrobial herbs, I also recommend using probiotics that contain the bacillus species (such as Megaspore), which I consider to be the traffic directors of the microbiome. These bacteria are able to rebalance your gut biome by supporting the good guys and telling the overgrowing or pathogenic bacteria that they need to go. Once we get the balance back then we can shift our strategy to maintaining the balance by eating a healthy, balanced, and diverse diet, along with potentially using a maintenance probiotic, which is going to contain lactobacillus and bifidobacterium in the range of 25 to 50 billion per day. It's important to consider that when trying to rebalance your gut microbiome, it's better to do it slowly. An aggressive change can cause the pathogenic bacteria to release toxins as a defense mechanism, and this can make you feel worse. Starting with very low doses of bacillus and antimicrobial herbs and listening to your body in the process is key to a good outcome. It's also important to think about the environment. If there's leaky gut, unhealthy cells, and inflammation, then the good bacteria will not thrive, so we need to be paying attention to making it a happy, healthy environment for the healthy bacteria and microbes to live in. What Are the Causes of a Disruption in the Microbiome? One of the main causes of dysbiosis, and one that I have been helping a lot of patients with through the years, is leaky gut. With leaky gut, the foods we eat “leak” through the intestinal lining because the intestinal cells have become damaged and there is more space between the cells. When undigested food leaks through the intestinal lining, the immune system responds in an effort to protect us, which leads to inflammation that can spread throughout the body. At the same time, the intestinal cells are not able to absorb nutrients from the foods we eat and, of course, our microbiome is disrupted. A poor diet, overconsumption of alcohol, smoking, stress and exposure to environmental toxins are all factors in developing leaky gut. The best protection is a healthful diet high in natural fiber and low in added sugars and processed foods. Another cause of dysbiosis is taking some types of medications like antibiotics, antacid medications, such as proton pump inhibitors, and many other medications. These meds will kill both good and bad bacteria, so we need to counteract this effect by taking the right probiotics. This is also why it is important to avoid the use of medications whenever possible. Stress is a major factor in the disruption of our microbiome. Stress includes psycho-emotional stress, trauma, as well as physical stressed and injuries. If you know you've been under stress, you're going to want to be proactive to help your microbiome to recover. We also know that gluten (in wheat, rye, barley, and spelt) disrupts the bacteria and decreases the levels of various kinds of healthy bacteria. If you're consuming gluten, and even if you don't have gluten sensitivity or celiac disease, there's a chance you're disrupting your gut bacteria. Also sugar, refined carbs, processed foods, non-organic foods, a low-fiber diet, pesticides, artificial sweeteners, artificial flavors and colors added to foods, all cause gut biome disruption. Exposure to toxins, such as toxins in our environment, our food, water, air, and exposure to mold toxins (such as if you're living in a water damaged building), all affect our digestion and they affect our microbiome. When it comes down to it, our gut biome is potentially being disrupted every day. It's by raising our awareness, and being mindful about what we eat, and how we recover from stress, that we are able to keep our gut microbiome optimized. What Are Some Products Out There That Can Help Rebalance the Microbiome? There is another new stool panel that not only tells us about the balance of bacteria in your biome, but then also offer custom probiotic formulations based on your results. So if you're low in certain strains of bacteria, then that's what they're going to put in your individualized probiotics. That company is called Flore and I can help you with that through my office if you're interested in trying that out as a way to re-optimize your gut biome. There's recent research that's identifying individual strains of bacteria and how they specifically help us with our health. I think we're going to see more and more products, such as supplements or beverage products, that contain these specific bacteria based on research that shows how they're potentially beneficial for our health. For example, there's one type of bacteria called Bifidobacterium 1741, which is considered a “psychobiotic” because it's been shown in research to help with stress recovery, specifically to bring cortisol down. So, in terms of the Stress Types I identified, this would be especially helpful for a Stress Magnet, or Night Owl, or Sluggish and Stressed type, who have elevated cortisol levels. If you want to find out your Stress Type, you can do my free online Stress Type Quiz here. Bifidobacterium 1741 has also been shown to help with mental health in terms of cognition, focus and memory. This type of bacteria can be found in products like Zenbiome - Zenbiome Cope and Zenbiome Sleep. There's also Bifidobacterium 35642 which has been shown to modulate inflammation. This would be especially helpful for someone who is experiencing a lot of inflammation and pain. Zenbiome Dual contains both Bifidobacterium 1741 and 35642. https://doctordoni.com/product/zenbiome-dual-60-capsules/ There's also quite a lot of research on the bacteria related to the vaginal biome and how it is completely related to the health of the gut biome. This is so important because if you're having vaginal symptoms or recurrent vaginal infections, like yeast, BV, or HPV, we know it is important that we heal your gut biome in order to help heal the vaginal biome and prevent those infections from happening. If you want to learn more about the vaginal biome related to the gut biome you can watch Episode #168 of How Humans Heal here. If you're interested in a probiotic that is specifically formulated to support a healthy vulvovaginal microbiota you can find one here. And another here. https://doctordoni.com/product/ortho-biotic-womens-30-capsules/ More examples of specific oral probiotics to benefit areas of the body and for certain purposes are: * Bifidobacterium HU36 - shown to help with carotenoid and the skin. https://doctordoni.com/product/sereneskin-30-capsules/ * Lactobacillus rhamnosus DR7, which has been shown especially to be helpful for mood and stress recovery or bacteria that has been shown to help with our neurotransmitters like serotonin and dopamine. *Bifidobacterium BPL1 which has been shown to help with weight gain around the waist. One more approach that is being used, especially in cases where there is the need to control an infection called Clostridium difficile, or C. diff (which is a pathogenic bacteria that a lot of times is hard to treat and get rid of) is something called a “fecal transplant.” A fecal transplant is a procedure to collect feces from a healthy donor and introduce them into a patient's gastrointestinal tract. Research shows that a fecal transplant can restore healthy bacteria in the lower intestine, which can help control C. diff and keep it from coming back. In some cases this can be more effective than antibiotics for keeping C. diff in check. Still, even after using a specific probiotic, or having a fecal transplant, we will need to come back to rebalancing and maintaining the overall population and diversity of bacteria based on what we eat and supporting healthy digestion. How to Integrate Microbiome Optimization into Your Overall Health Plan? No matter what, I think it's important to keep in mind that we need to take into account all of the root causes of our health issues. Yes, we can take a bacteria-containing supplement, and we can learn to consume an optimal amount of prebiotics to feed our biome, and all that can help, but we also need to work on our recovery from stress and anything else that was thrown out of balance by stress. We need to ensure optimal cortisol levels because cortisol determines the signals to our digestion. We need to optimize hormone levels such as insulin and blood sugar levels, thyroid, as well as leptin and the sex hormones. We need to address nutrient deficiencies and toxins. We have to address all the underlying causes to really shift the imbalances permanently and achieve our best health and resilience to stress going forward. If you really want to heal there needs to be a whole protocol put into action for your specific body. This is why I encourage you to refer to my overall stress recovery protocol because I'm addressing all the potential imbalances, not just the microbiome. Yes, the microbiome is hugely important, but we have to also think about all the other potential imbalances along with it because then everything can help maintain resilience together. So, as you can see, there are many solutions - many ways to help you rebalance your microbiome. I've worked with some of the most challenging and complex cases - people who were put on the most strict diets and worked with many other practitioners - and I've helped guide them back out of it to heal their digestion, optimize their biome and help them feel better. That's where I get my confidence to say it's possible to get your microbiome back on track again. If you want to work on your gut health and microbiome you may want to sign up for my Heal Leaky Gut Program where I teach you how to heal leaky gut with my proven protocol. Keep in mind that 50% of people with leaky gut, have zero symptoms, so the only way to know for sure is to do the food sensitivity panel I recommend. If you're interested in learning more about my approach to healing HPV you can find my new HPV Recovery Guide here. If you are tired of this virus and are really committed to erasing it from your life forever, you can sign up for my Say Goodbye to HPV 12-Week Program here. If you want to feel better by rebalancing your cortisol and neurotransmitters, start with this home test kit. You can also sign up for my Stress Warrior Program here. Also, if you want to learn more about how to recover from stress so that you can get back to feeling your best, you may want to read my book Master Your Stress Reset Your Health. In the book, I also share the quiz I developed to help you identify how stress has affected you specifically by knowing your Stress Type. You can also take this Stress Type Quiz online. For the most comprehensive support, even with the most difficult health issues (physical or mental), it is best to meet with me one-on-one, which is available to you no matter where you are in the world (via phone or zoom). You can set up a one-on-one appointment with me here. We're here to help you! Connect with Dr. Doni: Facebook HTTPS://FACEBOOK.COM/DRDONIWILSON Instagram HTTPS://INSTAGRAM.COM/DRDONIWILSON YouTube HTTPS://YOUTUBE.COM/USER/DONIWILSONND Weekly Wellness Wisdom Newsletter: HTTPS://DOCTORDONI.COM/WWW - Additional Resources: If you want to work on your gut health and microbiome you may want to sign up for my Heal Leaky Gut Program (https://doctordoni.com/leaky-gut-program) where I teach you how to heal leaky gut with my proven protocol. If you're interested in learning more about my approach to healing HPV you can find my new HPV Recovery Guide here (https://doctordoni.com/ddpp/hpv-guide/). If you are tired of this virus and are really committed to erasing it from your life forever, you can sign up for my Say Goodbye to HPV 12-Week Program here (https://drdoni.lpages.co/hpv-12-week-program/). You can also sign up for my Stress Warrior Program here (https://doctordoni.com/stress-program). Also, if you want to learn more about how to recover from stress so that you can get back to feeling your best, you may want to read my book Master Your Stress Reset Your Health (https://doctordoni.com/master-your-stress/). In the book, I also share the quiz I developed to help you identify how stress has affected you specifically by knowing your Stress Type. You can also take this Stress Type Quiz online (https://doctordoni.com/quiz/stress-quiz/) For the most comprehensive support, even with the most difficult health issues (physical or mental), it is best to meet with me one-on-one, which is available to you no matter where you are in the world (via phone or zoom). You can set up a one-on-one appointment with me here (https://doctordoni.com/work-with-me/) Disclosure: Some of the links in this post are product links and affiliate links and if you go through them to make a purchase I will earn a commission at no cost to you. Keep in mind that I link these companies and their products because of their quality and not because of the commission I receive from your purchases. The decision is yours, and whether or not you decide to buy something is completely up to you.
Our special guest for today is Dr. Sabine Hazan, a renowned Gastroenterologist, Scientist, Speaker, and CEO of ProgenaBiome. With 30 years of experience in the medical field and over 300 clinical trials for the FDA, she is an expert in the microbiome. She's also the author of a book called "Let's Talk Shit." Over these last couple years, Dr. Hazan's lab was one of the first to identify Covid in the stool of infected individuals, and her groundbreaking research has also seemed to uncover a correlation between low bifidobacterium (a strain of flora in our gut) and poor immune health. Due to the ownership of her own lab, she shares information that you won't find on the news. Her work with microbiome, and case studies of fecal transplants improving some commonly known diseases, is nothing short of extraordinary. Get ready to be amazed by her knowledge and expertise and glean a whole new respect for the wonders of our microbiome. Dr. Hazan's Instagram DONATE to the Microbiome reserach Foundation **Stay informed by SUBSCRIBING to the 'Know Better | Do Better' Newsletter. Receive exclusive guest notifications and special content available only to our subscribers. Don't miss out, SUBSCRIBE NOW! Connect with Autumn on Instagram Facebook TikTok Discover the 'Know Better | Do Better' Storefront on Amazon!
Semaglutide aka Ozempic is a GLP-1 agonist that's been around for a long time, suddenly Hollywood elites are now promoting it for fat loss. Here's the science you need to know. Sponsored: Support your Workout Sessions and Healthy Hydration with this Creatine Electrolyte Combo by MYOXCIENCE Save 15% with code podcast at checkout Video and Images: https://bit.ly/3wpnpAE Research Mentioned: Wilding, J. P. H. et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. New Engl J Med 384, 989–1002 (2021). Sharma, D., Verma, S., Vaidya, S., Kalia, K. & Tiwari, V. Recent updates on GLP-1 agonists: Current advancements & challenges. Biomed Pharmacother 108, 952–962 (2018). Show Notes: 0:20 Semiglutide is a GLP-1 agonist. 00:30 GLP-1, glucagon like peptide 1, functions under the category of gastrointestinal incretin hormones that helps you process the foods you eat. It improves insulin sensitivity. Decreases glucagon. 01:30 About 80% of the mechanisms of bariatric surgery is by amplifying the release of incretin hormones. 02:00 There was a 14% loss of body weight in study participants. 02:50 Semiglutide exerts stress on pancreatic beta cells, with an increased prevalence of pancreatitis and potentially pancreatic cancer. 04:40 GIP and GLP-1 are released after eating to increase insulin secretion from beta cells and prevent post-meal glucose excursions. 05:50 The diminished activity of GIP and GLP-1 is a feature of type-2 diabetes, beta cell insulin resistance, an obesity. 07:10 Exercise increases the release of gastrointestinal incretin hormones. 07:25 Berberine increases gut hormones and changes your microbiome. 07:40 These incretin hormones control the ecosystem of your gut microbiome and can improve function of immune cells around your gut. 08:10 Bifidobacterium can lead to a healthier GI incretin response. 09:00 GABA and L-glycine. 09:45 Protein and fat. 10:30 Polyphenols
VIDEO: Tulsi Gabbard: Zelenskyy shut down the biggest Ukrainian church in the country (3:18) Tulsi Gabbard destroys Trudeau #trudeaumustgo #canada #chrystiafreeland #tulsigabbard New leak claims FBI grilled Twitter on ‘state propaganda' (4:41) From the frontlines, the USEU/UK war on school playgrounds in Donbass. Eva Bartlett (6:58) Mediterranean diet linked to lower preeclampsia risk Cedars-Sinai Medical Center, December 22, 2022 In a new study evaluating the Mediterranean diet and adverse pregnancy outcomes, investigators from the Smidt Heart Institute at Cedars-Sinai found that women who conceived while adhering to the anti-inflammatory diet had a significantly lower risk of developing preeclampsia during pregnancy. The study, published in the peer-reviewed journal JAMA Network Open, also evaluated the association between the Mediterranean diet and other adverse pregnancy outcomes, including gestational diabetes and hypertension, preterm birth, delivery of a small-for-gestational-age infant, and stillbirth. “This multicenter, population-based study validates that a healthier eating pattern is associated with a lower risk of adverse pregnancy outcomes, the most exciting being a 28% lower risk for preeclampsia,” said Natalie Bello, MD, MPH, senior and corresponding author of the study and director of Hypertension Research in the Smidt Heart Institute. “Importantly, this connection between the Mediterranean diet and lower risk of adverse pregnancy outcomes was seen in a geographically, racially and ethnically diverse population.” Bello also notes that researchers found the association was stronger in women who are traditionally considered to be of advanced maternal age, those 35 or older. Preeclampsia is a serious blood pressure condition that develops during pregnancy and puts stress on the mother's heart. Left untreated, the condition can cause serious complications like weakened kidney and liver function and decreased blood supply to the fetus. In addition to preeclampsia, the risk of gestational diabetes also decreased in women who more closely followed the heart-healthy diet. The study was part of the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be, which enrolled 10,038 women . Of the women enrolled, 7,798 were included in the JAMA Network Open study. Women who were pregnant with their first child were asked to complete a semi-quantitative food frequency questionnaire during their first study visit, which occurred in the first trimester. The questionnaire focused on the women's eating habits during the three months prior to their visit and asked the participants to report their intake of common foods and beverages. Individuals' responses were then categorized into the nine components of a Mediterranean diet—vegetables, fruits, nuts, whole grains, legumes, fish, monounsaturated-to-saturated fat ratio, red and processed meats, and alcohol—to calculate a Mediterranean diet score. The data was compiled, analyzed and studied by researchers and showed: A high Mediterranean diet score was related to 21% lower odds of having any adverse pregnancy outcome, as well as a 28% and 37% lower risk of having preeclampsia/eclampsia and gestational diabetes. (NEXT) Almond findings continue to demonstrate prebiotic promise University of Florida, December 17, 2022 Eating almonds is beneficial to maintaining a healthy gut microbiota composition and improving the diet quality of parents and children suggests a new study. The research is the first to monitor the effects of dietary change on digestive health and immune function in a parent and child and whether this positively affects immunity, inflammation and general health. Writing in Nutrition Research, researchers began by enrolling 29 healthy parent and child pairs in to a 14-week, randomised, controlled, crossover study. Parents and children consumed 1.5 and 0.5 ounces of almonds and/or almond butter, respectively, on a daily basis for three weeks, as part of their usual diet, followed by a 6-week washout period and another 3-week period of following the usual diet with no almonds. Using the Healthy Eating Index (HEI) score—a measure of adherence to recommended dietary guidance—parents and children increased their scores to 61.4, (above national averages of 57.4 for adults 31-50 years and 54.9 for children 4-8 years). HEI scores also increased for fatty acids, total protein, seafood and plant protein and decreased for fruit and empty calories. When eating almonds, participants also consumed more vitamin E and magnesium, two nutrients lacking in the majority of adult's and children's diets. Almond consumption also seemed to change gut bacteria levels in subjects. Although the children consumed one-third of the amount of almonds compared to adults, microbiota was affected to a greater extent in their bodies. No specific changes in immune markers were noted. Last year, NutraIngredients reported on a study in which fibre-rich almonds and their skin may selectively boost the populations of Bifidobacterium spp. and Lactobacillus spp in the gut. The study suggested that populations of these bacteria were enhanced after six weeks of consuming almonds or almond skins. (NEXT) Probiotic bacteria found in fermented foods might help dispel bad breath Sichuan University (China), December 21, 2022 Probiotic bacteria usually found in fermented foods, such as yoghurt, sourdough bread, and miso soup, might help dispel the embarrassment of persistent bad breath (halitosis), finds a pooled data analysis of the available evidence, published in the open access journal BMJ Open. Lactobacillus salivarius, Lactobacillus reuteri, Streptococcus salivarius, Weissella cibaria, taken in the form of supplements in this study, may help freshen the breath, but more good quality research is needed, say the researchers. Volatile sulphuric compounds are the main cause of persistent bad breath. These compounds are produced by mouth bacteria as a result of bacterial mixing and food debris associated with poor gum and dental hygiene. Options used to tackle the problem include mouthwashes, chewing gums, teeth scaling and tongue scraping. Emerging evidence suggests that probiotic bacteria might offer a simpler alternative. To explore this further, and find out how long any such effects might last, the researchers trawled research databases for relevant randomised clinical trials published up to February 2021. Probiotics may inhibit the decomposition of amino acids and proteins by anaerobic bacteria in the mouth, so curbing the production of smelly by-products, the researchers explain. (NEXT) War metaphors for cancer hurt certain prevention behaviors University of Michigan, December 15, 2022 It's not unusual for people to use war metaphors such as “fight” and “battle” when trying to motivate patients with cancer. But a University of Michigan study indicates that using those words can have an unintended negative effect. David Hauser, a U-M doctoral student in psychology, and colleague Norbert Schwarz, found in three studies that exposure to metaphoric language relating cancer to an enemy significantly lessens the extent to which people consider cancer-prevention behaviors. “Hearing metaphoric utterances is enough to change the way we think about a concept,” said Hauser, the study's lead investigator. “When we hear the phrase ‘win the battle against cancer,' it forces us to think of cancer as if it's an enemy that we are at war with.”These metaphors emphasize power and taking aggressive actions toward an enemy. However, the bulk of cancer prevention behaviors–such as curbing alcohol intake, salty foods and smoking–involve limitation and restraint. None of them fit with an enemy metaphor that promotes power and aggression, the researchers said. “Hence, enemy metaphors de-emphasize this subset of beneficial prevention behaviors and hurts people's willingness to engage in them,” he said. In one study, the authors asked participants to list cancer-prevention behaviors they would be willing to undertake. For one group of participants, the request contained metaphors relating cancer to an enemy (“What things would you do to fight against developing cancer?”). For a second group, the request contained no metaphors. The group exposed to the enemy metaphor listed significantly less limitation-related prevention behaviors. “This suggests that simply seeing war metaphors for cancer diminishes the extent to which these behaviors come to mind,” Hauser said. In another study, 313 participants read one of two health information passages about colorectal cancer. One passage contained metaphors relating cancer to an enemy (“This disease involves an enemy uprising of abnormal cellular growth in the large intestine.”), whereas the second passage contained no enemy metaphors. Participants then rated the extent to which they intended to engage in various prevention, screening and treatment behaviors. Those who read the enemy metaphor passage had less intention to engage in limitation-related prevention behaviors (such as limiting red meat intake or excessive alcohol consumption) than the participants who read the second passage. “Enemy metaphoric language for cancer diminishes people's intentions for these types of prevention behaviors,” Schwarz said. “Importantly, these negative effects of enemy metaphors on prevention behaviors are not accompanied by a positive effect on intentions to undertake screening or treatment behaviors.” War and enemy metaphors are the most common metaphors found in science journalism about cancer, and they pervade public discourse about the disease.”Fight and battle are actually among the top 10 verbs used to describe cancer,” Hauser said. “Constant exposure to even minor metaphorical utterances may be enough to make enemy metaphors for cancer a powerful influence on public health–with unfortunate side-effects.” (NEXT) More proof that cannabis is an anti-aging powerhouse to rapidly restore memory performance of older mice Hebrew University Jerusalem & University of Bonn (Germany), December 14, 2022 Scientists from The Hebrew University of Jerusalem and the University of Bonn teamed up to examine the potential brain benefits of cannabis in mice. This amazing study is years in the making, with the researchers having built a strong body of evidence on the brain benefits of THC. To conduct their study, researchers administered a small amount of THC, derived from cannabis, to mice aged two, twelve and 18 months old for the course of one month. Some mice were given a placebo. As sources explain, mice have very short life spans and show substantial cognitive deficiencies at just 12 months of age. Afterwards, the mice were subjected to a battery of tests to gauge their learning capacity and memory. Incredibly, the team found that older mice treated with cannabis displayed cognitive function that was as good as the youngest control subjects. As reported by The Hebrew University of Jerusalem: Mice that were only given a placebo displayed natural age-dependent learning and memory losses. In contrast, the cognitive functions of the animals treated with cannabis were just as good as the two-month-old control animals. “The treatment completely reversed the loss of performance in the old animals,” reported Prof. Andreas Zimmer from the Institute of Molecular Psychiatry at the University of Bonn and member of the Cluster of Excellence ImmunoSensation. In past studies, the team found that brain aging is accelerated when THC receptors are absent, prompting them to investigate further. In the brain, THC acts very similarly to the cannabinoids naturally produced by the body. “With increasing age, the quantity of the cannabinoids naturally formed in the brain reduces. When the activity of the cannabinoid system declines, we find rapid aging in the brain,” Prof. Zimmer commented. Treating the mice with THC yielded incredibly impressive epigenetic changes in their brains, and the number of links between neurons dramatically increased, as well. “It looked as though the THC treatment turned back the molecular clock,” Zimmer commented. (NEXT) Brussels Sprouts Have As Much Vitamin C As Oranges – And Plenty Of Other Health Benefits Quadram Institute, December 22, 2022 For many people, Christmas dinner is not complete without a side helping of Brussels sprouts. Indeed, they are Britain's favourite Christmas dinner vegetable. But if you're not a convert, perhaps these health benefits will convince you to give them a second chance. Sprouts belong to the wholesome family of cruciferous or brassica vegetables, including cabbage, kale and broccoli. As with all brassica, Brussels sprouts are packed with fibre, which is good for keeping the beneficial bacteria in your gut happy. They also provide essential minerals, such as potassium and calcium, to keep your muscle and bones healthy. They are rich in vitamins K and C, supporting a healthy immune system and bones. Pound for pound, you'll get more vitamin C from them when eaten raw than from oranges. Cooked Brussels sprouts still contain vitamin C, though – about the same pound for pound as you'd get from orange juice and raw oranges.Most importantly, Brussels sprouts are rich in a wide range of natural chemicals, such as carotenoids and polyphenols, that have been linked to good health. They are particularly abundant in sulphur-containing compounds called glucosinolates. Several scientific studies have shown that these sulphurous compounds are potent antioxidants that can promote health by preventing cell damage. Several studies have also shown that consuming more of these glucosinolates from cruciferous vegetables, including Brussels sprouts, broccoli, kale and cabbage, are associated with a reduced risk of developing a wide range of cancers. Research continues collecting more evidence of their benefits, but the best advice to keep in mind is to try to consume roughly five portions of brassica vegetables weekly and to vary the options.
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Video: Nothing is more anti-woman than this. Gen Z Refuses to Grow Up | With Dr. Jean Twenge Tomato extract shows blood thinning potential versus aspirin: Study University of Aberdeen (Scotland), November 23, 2022 A proprietary tomato extract has been shown to thin blood in healthy people – but less severely than aspirin and without typical side-effects. The research – published in the European Journal of Clinical Nutrition concluded the lycopene-free extract “may be appropriate for use as a dietary antiplatelet.” Lead researcher Dr Niamh O'Kennedy working at the Rowett Institute of Nutrition & Health at the University of Aberdeen in Scotland told us the research showed tomato extracts could be used as alternatives to drugs like aspirin for blood thinning. This was especially the case for groups like the elderly who frequently were intolerant of drugs like aspirin typically prescribed for that purpose. “Platelet function is very tricky,” Dr O'Kennedy told us. “If you knock out the platelets it can have a bad effect on the body. And many treatments knock out too much. Some people respond strongly so bad they bleed. ” She added: “Results like this show that people and the medical world should start looking at dietary interventions like these that can have a big impact.” Platelet plugs usually form within 50-100 seconds. The researchers found platelet plugs were formed within 100-150 seconds among tomato extract users, compared to 300-600 seconds for aspirin users. Because of this more gentle effect, Dr Kennedy and her team suggested tomato extract could be a suitable dietary intervention to control platelet hyperactivity which increases with age, the onset of type II diabetes, mellitus, atherosclerosis and other conditions in subjects with low cardiovascular disease (CVD) risk. (Next) Use of penicillin early in life, even in low doses, affects the gut microbiome, contributing to brain inflammation and changes in behavior McMaster University (Ontario), November 18, 2022 It is truly unavoidable to catch a cold or contract a disease, especially with today's lifestyle trends and medical misinformation. A lot of the medicine we use to treat our health conditions may actually cause more harm than good. A St. Joseph's Healthcare Hamilton and McMaster University joint study found that low doses of penicillin administered to pregnant mice and their young results in behavioral changes that have long-term effects. The study, which was published in Nature Communications, reports that the behavioral changes noted in the mice included elevated levels of aggression, characteristic neurochemical changes in the brain, and imbalance in the gut microbiome of the mice. On the bright side, giving the mice a lactobacillus strain of bacteria managed to prevent the effects of the administered penicillin. Low-dose penicillin taken in late pregnancy and early life of mice offspring results in behavioral changes and imbalances in the microbes of the gut. While the tests were done on mice, there are increasing concerns about the long-term effects of antiobiotics in humans, according to Dr. John Bienenstock, director of the Brain-Body Institute at St. Joseph's Healthcare Hamilton and distinguished professor at McMaster University. Large doses of multipurpose antibiotics in adult animals have been shown to affect behavior, but none have been able to test the effects of clinical doses of commonly used antibiotics, such as penicillin, on the bacteria in the gut and in behavior. Almost all babies in North America have received some dose of antibiotics during their first year of life. Researchers are looking into analyzing the effects of the drug on the offspring of the mice if given only to the pregnant mothers (teratogenesis). Penicillin is the first type of medication that is effective against bacterial infections caused by staphylococci and streptococci, but is however, easy to build resistance against. Almost 10 percent of all people around the world are allergic to penicillin. (Next) High-dose vitamin C reduces inflammation in cancer patients, study shows Riordan Clinic (Wichita KS), November 22, 2022 The value and impact of a daily vitamin C supplement as well as high, concentrated doses for acute illnesses is becoming increasingly clear. Studies have already shown the efficacy of liposomal vitamin C in treating infections and as an anti-cancer therapy. Now, another study is confirming its effectiveness against inflammation in cancer patients, one of the primary markers. High levels of inflammation seem to indicate a higher risk of cancer as well as a less hopeful prognosis for healing and recovery. Inflammation impairs the immune system, plays a role in cachexia, lowers toleration of numerous cancer treatments, and generally decreases health and quality of life. This study made use of high-dose intravenous vitamin C (IVC) treatments and analyzed their effects. The results found indicate great promise for the use of high-dose intravenous vitamin C treatments to help reduce inflammation in cancer patients, which is one of the major factors of cancer and its progression. Markers of inflammation such as pro-inflammatory cytokines and C-reactive protein tumor markers showed a positive response to vitamin C treatments, with inflammation reduced significantly. This improvement correlated with reduced tumor size and the hindrance of the cancer's ability to metastasize. Vitamin C is especially valuable in extremely high doses taken either orally or intravenously. A range of cancers have been proven to benefit from vitamin C treatments, including cancers of the prostate, breast, skin, bladder, lung, pancreas, thyroid, and B-cell lymphoma. This research was conducted by Riordan Clinic scientists and published in the Journal of Translational Medicine. When supplementing with liposomal vitamin C orally for major health issues, 10,000 to 12,000 mg per day should be taken. This dose can be taken in 2,000 to 4,000 mg doses gradually throughout the day to aid absorption. (Next) Having trouble sleeping? Try exercise! Norwegian University of Science and Technology, December 1, 2022 The vast majority of people have trouble sleeping from time to time. However, 10 to 20 per cent of the population struggle more than the rest of us and have serious long-term sleep problems. Many people who struggle with insomnia sooner or later resort to some form of sleeping aid. However, one study of more than 34 000 adults would suggest that some of them should exercise instead. “We've observed that people who are in better physical condition have a lower risk of taking prescription sleeping pills,” says Linda Ernstsen, an associate professor at the Norwegian University of Science and Technology's (NTNU) Department of Public Health and Nursing. The researchers reviewed participant data in Norway's large Trøndelag Health Survey (The HUNT study). A total of 240 000 people from Trondheim have taken part in the survey since it began in 1984. Four survey rounds have been carried out to date. “Almost 5800 of the participants received their first prescription sleep medication during the study period,” says Ernstsen. This means that approximately 17 percent of the participants' sleep issues were serious enough to warrant a prescription from their doctor. But the participants who were in the best condition used fewer of these prescription drugs. “These findings suggest that being physically fit can also help you sleep better,” Ernstsen says. Unfortunately, the beneficial effect of exercise is stronger for men than for women. The findings show that the fittest men had a 15 per cent lower risk of needing drugs for troublesome sleep issues. “The corresponding percentage risk for the fittest women was much lower. But women who struggle with sleep can still benefit from getting in better shape,” says Ernstsen. (Next) New study puts gut microbiome at the center of Parkinson's disease pathogenesis University of Alabama at Birmingham, December 1, 2022 New research from the University of Alabama at Birmingham says the gut microbiome is involved in multiple pathways in the pathogenesis of Parkinson's disease (PD). The findings, published in Nature Communications, show a wide imbalance in microbiome composition in persons with Parkinson's disease. The study is the largest microbiome study conducted at the highest resolution. The investigators employed metagenomics, the study of genetic material recovered directly from the stool microbiome of persons with PD and neurologically healthy control subjects. “The primary aim of this study was to generate a full, unaltered view of the imbalance in PD gut microbiome,” said Haydeh Payami, Ph.D., professor in the Marnix E. Heersink School of Medicine Department of Neurology and senior author on the study. The study reports Parkinson's disease metagenome is indicative of a disease-promoting microbiome. “We found evidence for multiple mechanisms that we know are linked to PD, but we didn't know they were happening in the gut also and are orchestrated by the microbiome,” Payami said. Investigators found an overabundance of opportunistic pathogens and immunogenic components, which suggest infection and inflammation at play, overproduction of toxic molecules, and overabundance of the bacterial product curli. This induces PD pathology and dysregulation of neurotransmitters, including L-dopa. At the same time, there was a shortage of neuroprotective molecules and anti-inflammatory components, which makes recovery difficult. The researchers studied 257 species of organisms in the microbiome, and of these, analysis indicated 84, more than 30%, were associated with Parkinson's disease. “Of the 84 PD-associated species, 55 had abnormally high abundance in persons with PD, and 29 were depleted,” Payami said. “We found that over 30% of the micro-organisms and bacterial genes and pathways tested have altered abundances in Parkinson's disease, which indicates a widespread imbalance.” At one end of the spectrum, Bifidobacterium dentium was elevated by sevenfold, Actinomyces oris by 6.5-fold and Streptococcus mutans by sixfold. At the other end of the spectrum, Roseburia intestinalis was reduced by 7.5-fold and Blautia wexlerae by fivefold. Overall, 36% of PD-associated species had higher than twofold change in abundance, reflecting a 100% to 750% increase or decrease in PD versus the healthy control group. “This is exciting research, as metagenomics is a new, albeit fast-evolving field, and the resources, methods and tools, while state-of-the-art, are still in development,” Payami said. (Next) Five precepts of Buddhism may be linked to lower depression risk Study suggests the moral practice may buffer known links between high stress levels and depression Chiang Mai University (Thailand) & Károli Gáspár University (Hungary), November 30, 2022 A new study suggests that people with high levels of neuroticism and stress may be at greater risk for depressive symptoms, but those links could be buffered for people who observe the five precepts of Buddhism—a fundamental system of ethics for the religion's followers. The five precepts of Buddhism guide followers not to kill, steal, engage in sexual misconduct, tell ill-intentioned lies, or use intoxicants. Previous research suggests that observing the five precepts can boost wellbeing and quality of life for the general public, including nonserious followers. However, it has been less clear whether the five precepts could ease symptoms of depression for those at higher risk. To address this question, Wongpakaran and colleagues focused on known links between neuroticism, stress, and depression. Prior research has shown that greater neuroticism is associated with greater risk of depression, both directly as well as indirectly through perceived stress—how people think and feel after stressful life events. From late 2019 through September 2022, the researchers conducted an online survey of 644 adults in Thailand. The survey included standard questionnaires to measure each participant's levels of perceived stress, neuroticism, and depressive symptoms, as well as their observance of the five precepts of Buddhism. Statistical analysis of the survey results showed that observing the five precepts to a high degree appeared to buffer the influence of perceived stress on depression. These results suggests that people with high levels of neuroticism and stress may be less likely to develop depressive symptoms if they follow the five precepts closely. The researchers note that, while their study suggests potential benefits for the five precepts in the context of depression, it does not confirm a cause-effect relationship. A large proportion of participants were female and people who lived alone, and participants' religious involvement was unknown, although 93.3% reported that they were Buddhist. More research will be needed to determine whether these findings might extend to the general population of Thailand and beyond, as well as to non-Buddhists. The authors add: “The five precepts practice makes other people feel safe, as all these behaviors are harmless, and it potentially provides the stressful practitioner with a buffer against depression.”
WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Support Immune & Digestive Health: https://justthrivehealth.com, use code ASPREY to get 15% offMeat Sticks and More: https://paleovalley.com/DAVE, use code DAVE to get 15% off your first orderControl Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentSPECIAL OFFER FOR BULLETPROOF RADIO LISTENERS: Go to https://justthrivehealth.com. You'll find their new line, Joot, and their new Just Calm probiotic for stress management and mood support. Just Calm features the proprietary “psychobiotic” strain BL 1714™ combined with brain-nourishing B vitamins. You'll also find other products that tackle gut health and inflammation. Use code ASPREY to get a 15% off discount.IN THIS EPISODE OF THE HUMAN UPGRADE™...…you'll learn about a strain of probiotics called psychobiotics. This strain shows promising effects on stress relief, anxiety, mood, sleep and other important gut-brain axis connections.Microbiologist Kiran Krishnan, Ph.D., explores the human microbiome and how it functions so you can have better gut health. He has an extensive research background in the fields of molecular medicine and microbiology. His particular expertise lies in gut commensal spore bacteria microbiology.He's been a guest on the show before to educate listeners about probiotics and the connections between your microbiome, inflammation and immune function. This time, he's sharing exciting research about a probiotic strain that's tackling the gut-brain axis, called Bifidobacterium longum 1714™.Kiran says, “One really important message that I want people to really wrap their heads around and understand when we're talking about the gut-brain axis is, of course, the gut. A healthy gut is incredibly supportive to the brain. It supports the brain in a number of really important critical functions like recovery, for example, or production of serotonin and dopamine and all these important neurotransmitters, but on the other end of the spectrum, an unhealthy gut is not only not supportive, but it's arguably one of the most toxic things for the brain.”Big topics covered in this episode include:Basic mechanisms by which the gut microbiome can influence neurochemicals and brain inflammationThe gut-brain connection as it relates to stress coping and mental healthHow cortisol and interleukin 6 drive stress response and inflammation in your whole bodyVariables that can cause a breakdown or dysfunction in the psychobiomeTherapeutic interventions, including psychobiotics that can help correct gut-brain axis dysfunctionKiran's great at explaining the science so you clearly understand what the studies mean and can apply new knowledge to your own biology. He also partners with Just Thrive Health on product research and development.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.