Podcast appearances and mentions of roland pease

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Best podcasts about roland pease

Latest podcast episodes about roland pease

Science in Action
Nobel convergence

Science in Action

Play Episode Listen Later Oct 10, 2024 38:04


In the week the Nobel prizes for science are announced, Roland Pease takes a look at the stories behind the breakthroughs being recognized, and the themes that connect them. From the discovery of the tiny fragments of RNA that regulate our cells' behaviour, via computer structures that resemble our brains, and harnessing those sorts of computers to design drugs and medicines, it has been one of the most interdisciplinary years for the prize panellists. We hear from old students, recent colleagues, laureates and lab (and life) partners, including Rosalind “Candy” Lee and her husband Victor Ambros, of UMass Chan Medical School, US, Erika DeBenedictus of the Crick Institute, UK, and Dmitri Krotov of IBM Research. Presented: Roland Pease Produced: Alex Mansfield Production co-ordinator: Andrew Rhys Lewis(Photo: 3d rendering of RNA strands and lipid-based nanoparticles or liposome. Credit: Love Employee via Getty Images)

Public lecture podcasts
Research with Impact with Roland Pease Episode 7: Alumni making an Impact

Public lecture podcasts

Play Episode Listen Later Sep 25, 2024 37:34


In this Special Episode, Roland Pease meets three University of Bath graduates who are making impacts in industry. Claire Smith is Director of Buro Happold in Bath. A structural engineer, she discusses her work in the city and beyond - and in boosting the sustainability of a local landmark, Bath Abbey, by combining cutting-edge technology with the city's natural hot springs. Meri Williams has held multiple leading management roles since completing her degree in Computer Information Systems, leading scale-ups and expansions of major names including Gov.uk, Procter & Gamble and now at financial services company Pleo, with a focus on recognising and encouraging diversity in teams. Bharat Shah was one of the first students to graduate from the University of Bath. He has grown a pharmacy wholesale business, Sigma Pharmaceuticals, from scratch and has a unique view into pharmacists' future as part of the UK healthcare system.

BBC Inside Science
Going for gold

BBC Inside Science

Play Episode Listen Later Sep 5, 2024 28:02


Today we will be going for gold in more ways than one. Inga Doak, the Head of Sustainability at The Royal Mint, reveals how the company plan to ‘urban mine' gold from household electronic waste and turn it into jewellery. But with tens of millions of tonnes of e-waste piling up every year, the environment policy adviser at the Royal Society of Chemistry, Izzi Monk unpacks how the UK can clean up its act. Vic puts her stable boots on to visit some very pampered thoroughbred foals to find out what their poo can reveal about their future success on the racecourse. From horses to humanity, sports geneticist Alun Williams discusses how our genetic make-up could determine whether or not we are destined for gold at the Olympics. Plus, Roland Pease channels his inner child to investigate his youthful obsession with Mars as NASA looks for new microbial life on the red planet. Presenter: Victoria Gill Producers: Ben Mitchell and Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

Science in Action
Examining NASA's new evidence for Martian life

Science in Action

Play Episode Listen Later Aug 1, 2024 29:32


NASA's Perseverance Rover has found a fascinating rock on Mars that may indicate it hosted microbial life billions of years ago. Abigail Allwood, exobiologist at NASA's Jet Propulsion Lab, is on the team scrutinising the new Martian data. And a couple of newly discovered, approximately 500 year old fossils from the ‘Cambrian explosion' of complexity caught presenter Roland Pease's eye this week. First Martin Smith from Durham University tells us about a tiny grub that's ancestor to worms, insects, spiders and crustaceans. Then Ma Xiaoya, who has positions at both Yunnan University in China and Exeter University in the UK, tells us about a spiny slug that was also discovered in a famous fossil site in China. And the first sightings of the landscapes on the underside of the ice shelves that fringe Antarctica. These float atop the ocean around the frozen continent but effectively hold back the glaciers and ice sheets on the vast landmass. Their physical condition therefore is pretty critical in this warming world, Anna Wohlin of Gothenburg University tells us. Presenter: Roland Pease Producer: Jonathan Blackwell Production Co-ordinator: Jana Bennett-Holesworth (Image: NASA's Perseverance Mars rover taking a selfie on Mars. Credit: NASA/JPL-Caltech/MSSS)

Science in Action
A humungous temporary tentacle

Science in Action

Play Episode Listen Later Jun 6, 2024 38:47


The ‘origami' superpowers of a single-celled pond hunter, it hunts by launching a neck-like proboscis that can extend more than 30 times its body length. Manu Prakash of Stanford University reveals the amazing mathematical mechanisms of the protist, Lacrymaria olor. Research from Elana Hobkirk at Durham University has found that the process of domestication and selective breeding has limited the ability of domestic dogs to use facial expressions to convey emotions as effectively as their wolf ancestors. Whilst we may be easily manipulated by the ‘puppy eyes' of our pet dogs, they are no longer able to display the same range of emotions that wolves can, who need strong visual communication to maintain their packs. Who discovered the first black hole? Science writer Marcus Chown tells us about the discovery of Cygnus X-1 discovered by Paul Murdin and Louise Webster in 1971. And 100 years ago this week, Indian physicist Satyendra Nath Bose posted his revolutionary paper to Albert Einstein, which went on to influence quantum mechanics, low-temperature physics, atomic physics, and the physics of the particles that shape the Universe. Physicist Ajoy Ghatak and presenter Roland Pease discuss the story of the man who had the word ‘boson' coined to memorialise him in the late 1920s. Also in the longer podcast version: It's a microbe-eat-microbe world out there, with bacteria waging constant war against each other. It's by dipping into their ever-evolving chemical arsenal that we keep our pharmacies supplied with the antibiotics we use to fight infectious bacteria - and computer biologist Luis Coelho of Queensland University of Technology has turned to genetics and AI to speed up the search for novel compounds. Presenter: Roland Pease Producer: Jonathan Blackwell Production Coordinator: Jana Bennett-Holesworth

BBC Inside Science
Ugly animals and asteroid Apophis

BBC Inside Science

Play Episode Listen Later May 30, 2024 28:00


One year ago, the World Health Organisation declared that COVID-19 would no longer be categorised as a global health emergency. But the pandemic has left us with a new normal in all areas of our lives. From vaccine rollout to wastewater monitoring, we're asking: how has COVID altered the scientific landscape? Marnie Chesterton is joined in the studio by Linda Geddes, science journalist, and Barbara Kasprzyk-Hordern, Professor in Environmental and Analytical Chemistry at the University of Bath, to discuss.Are ugly animals getting the short end of the conservation stick? Whilst a few beautiful creatures, like tigers and panda bears, get good marketing and attract the most conservation efforts, comedian and biologist Simon Watt argues that the endangered animals which are less pleasing to the eye are being forgotten.Also this week, we answer a listener's question about the accuracy of using bug splats on cars to measure insect populations. Lead data analyst from the Kent Wildlife Trust, Lawrence Ball, gives us the details about the national citizen science survey, Bugs Matter, which sees people around the country measure insect splats on vehicle number plates as a marker of insect abundance.And science journalist Roland Pease discusses the unprecedented scientific opportunity hurtling towards Earth in the form of asteroid Apophis. It will just miss our planet – in astronomical terms at least – but its proximity has astronomers excited. Presenter: Marnie Chesterton Producers: Ella Hubber, Sophie Ormiston and Hannah Robins Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth

Science in Action
An armada for asteroid Apophis?

Science in Action

Play Episode Listen Later Apr 25, 2024 26:29


Friday, April 13th 2029 – mark it in your calendar. That's the day an asteroid the size of an aircraft carrier will fly past Earth, closer than some satellites. Don't worry – it will miss, but it'll will pass so close to Earth that it will be visible to the naked eye of 2 billion people, particularly in North Africa and Western Europe.Roland Pease this week attended the Apophis T-5 Years conference at the European Space Research and Technology Centre (ESTEC) in the Netherlands, meeting astronomers scrambling to get missions up to the object to learn what kind of threats such asteroids might pose to us in the future and to discuss the science of planetary defence. NASA's OSIRIS-APEX, a follow-on to OSIRIS-REx, will study the physical changes due to the gravitational forces from the Earth as it closely passes us by. But will there be an armada of spacecraft sent to monitor Apophis? The European Space Agency hope to gather support for their own mission, RAMSES.Presenter: Roland Pease Producer: Jonathan BlackwellImage Credit: JPL/Caltech

BBC Inside Science
The Gulf Stream's tipping point

BBC Inside Science

Play Episode Listen Later Mar 14, 2024 28:01


The Gulf Stream, also known as the Atlantic Meridional Overturning Circulation (AMOC), is essential to stable global climate, and the reason we have moderate temperatures in Northern Europe. Now, a new modelling study suggests that this circulation could, at some point, be at a tipping point and collapse. We hear from one of the minds behind the model, post-doctoral researcher René van Westen from Utrecht University. But how likely is it that this will actually happen in the real world? Presenter Victoria Gill speaks to Jonathan Bamber who cautions that a gulf stream collapse is not imminent, and that it may just weaken slowly over time. Every summer in the Hudson Bay, on the Eastern side of Arctic Canada, the sea ice melts and the region's polar bears head inland. But that ice-free season is getting longer, depriving the bears of that frozen platform that they use to pounce on their favourite prey – seals. So what do the bears do all summer? Research Wildlife Biologist Karyn Rode shares how she and her colleagues put a collar with video cameras on 20 polar bears, and what it revealed about their lives. Is CERN finally going to get a gigantic new particle accelerator? Almost exactly one decade ago, Roland Pease reported from Switzerland about the very first meeting about the successor of the Large Hadron Collider which was used to discover the Higgs Boson. Now there's an update to the story. Roland is back to tell Vic how far along CERN is with their plans, and how much more time and money it will take to build the Future Circular Collider. Lovers of certain famous, creamy French cheeses could be in for a bit of a shock. Camembert and Brie are facing extinction as we know them! The Centre National de la Recherche Scientifique (CNRS) in Paris has stated that, over the last 100 years, the food and farming industry has placed too much pressure on the production of these types of cheeses. Now, the fungus traditionally used to grow the famous, fluffy white rinds has been cloned to a point where the lack of diversity in its genetic makeup means it can no longer be reproduced. Turophiles must learn to appreciate more diversity of tastes, colours and textures to protect the cheeses' future. Presenter: Victoria Gill Producers: Florian Bohr, Louise Orchard, Alice Lipscombe-Southwell  Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth  BBC Inside Science is produced in collaboration with the Open University.

Public lecture podcasts
Research with Impact with Roland Pease Episode 6: The Science of Pain

Public lecture podcasts

Play Episode Listen Later Jan 11, 2024 34:41


In Episode Six of the University of Bath's Research with Impact podcast, Roland Pease visits the Centre for Pain Research to find out how its academics are helping people who suffer from pain. How big an issue is it? Is it a subjective problem - and how to we quantify pain? How can we help minimise or alleviate pain? And how do we research pain in young people? Joining Roland are Professor Christopher Eccleston, Dr Emma Fisher and Professor Ed Keogh. This episode was recorded in October 2023.

Science in Action
Tackling tuberculosis in South Africa

Science in Action

Play Episode Listen Later Jan 4, 2024 29:36 Very Popular


In this episode of Science in Action, we find out that tuberculosis (TB) is the leading cause of death in South Africa. After visiting a clinic dedicated to the diagnosis and treatment of TB, Roland Pease meets researcher Professor Grant Theron at Stellenbosch University, who explains why the disease is still so prevalent. Next we hear from Professor Novel Chegou and his student Candice Snyders, also based at Stellenbosch University. They are researching biomarkers to diagnose tuberculosis and have already successfully developed a rapid finger-prick test to identify TB. Roland then chats to vaccine researcher Professor Thomas Scriba at the University of Cape Town, who reveals more about the current landscape of TB vaccination. Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production co-ordinator: Jana Bennett-Holesworth

Science in Action
Following in the footsteps of ancient humans

Science in Action

Play Episode Listen Later Dec 28, 2023 28:27 Very Popular


In this special episode of Science in Action, Roland Pease travels to South Africa to gain a deeper understanding of human origins. Along the way, he speaks to ichnologist Charles Helm and national parks ecologist Mike Fabricius, who take him to a special – and extremely windy – location, where early human footprints are permanently preserved in the rock. At the University of Cape Town, Roland speaks to Rieneke Weij and Georgina Luti. They are studying the geochemistry of rocks that existed in caves alongside our ancient relatives. Across the city, in the Iziko South African Museum, Wendy Black and Amy Sephton discuss the ways in which we think about our deep past and how we can decolonise the human story. Presenter: Roland Pease Producer: Ella Hubber Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth (Image: Human fossilized footprint in hardened mud or clay. Credit: Waltkopp/Getty Images)

Science in Action
Volcanic eruption lights up Iceland

Science in Action

Play Episode Listen Later Dec 21, 2023 31:28 Very Popular


This week, the Reykjanes volcano in Iceland has erupted, following weeks of seismic activity. Edward Wayne Marshall, from the University of Iceland, brings us the latest science about the volcano. Also this week, the UK's 40-year-old JET fusion facility has been switched off. Roland Pease went along to watch. Fusion facilities are trying to create clean energy by replicating the processes in the Sun. And the Sun itself is currently approaching solar maximum, which means we may get to enjoy more spectacular auroras but could also experience widespread radio blackouts. Solar physicist Dibyendu Nandi, from the Centre of Excellence in Space Sciences in Kolkata, tells us more. And in the outer reaches of our Solar System, the iconic Voyager 1 craft has started sending back nonsense data. William Kurth, who has worked on Voyager since its launch in 1977, reveals his personal and scientific connection to the mission. Presenter: Roland Pease Producer: Alice Lipscombe-Southwell Editor: Martin Smith Production Co-ordinator: Jana Bennett-Holesworth (Image: Volcano Erupts On Iceland's Reykjanes Peninsula. Credit: Micah Garen/Getty Images)

Public lecture podcasts
Research with Impact with Roland Pease Episode 5: 'We need to talk about Artificial Intelligence'

Public lecture podcasts

Play Episode Listen Later Dec 14, 2023 34:11


In Episode Five of the University of Bath's Research with Impact podcast, Roland visits two researchers at the forefront of debates surrounding AI development and regulation. First up, it's Nello Cristianini, Professor of Artificial Intelligence from Bath's Department of Computer Science. With a focus on machine learning, data science, computational social science, philosophy of AI and regulation of AI, Nello's book "The Shortcut: Why Intelligent Machines Do Not Think Like Us", considers how AI is embedded across our technologies, infrastructure and all our lives and asks whether we should be concerned and what should we do. Roland also heads to our Department of Social & Policy Sciences to talk to Professor Emma Carmel. Emma is Professor of Governance and Public Policy with a particular focus on how public policies, and public and private organisations interact to shape society. Emma's work has analysed social and labour market policies, migration, and most recently, AI technologies. She is interested in how AI systems are used by governments, and how this is changing the relationship between state, society, citizens and technologies. She also works on the public policy challenges that the adoption of AI presents in different settings and how it can be regulated. Among other work, Emma is co-editor of a major new international handbook on AI and Public Policy, is launching a book series on Governance, Technology and Society (Edward Elgar) in 2024. This episode was recorded in October 2023.

Public lecture podcasts
Research with Impact with Roland Pease Episode 4: 'A bright future for solar energy'

Public lecture podcasts

Play Episode Listen Later Dec 6, 2023 30:40


In Episode Four of the University of Bath's Research with Impact podcast, Roland Pease heads to the roof of the Chancellors' Building to discuss the future of solar energy with experts leading the way at the University of Bath. In this episode he meets: Professor Alison Walker from Bath's Department of Physics. Alison's research concerns multiscale modelling of perovskite solar cells and organic devices such as displays. In 2019, she chaired the Solar Commission whose aim was to show how UK innovation and industrial capabilities could be harnessed to allow the UK to be a global player in solar in the years ahead. The report was launched in the House of Lords. She directs the 7 university Centre for Doctoral Training in New and sustainable photovoltaics, CDT-PV. Locally, students funded by the CDT-PV worked with Bath Abbey to explore how could be installed on historic buildings to reduce emissions. Professor Petra Cameron from Bath's Department of Chemistry. Her group researches energy materials and makes perovskite solar cells. She focuses on understanding ion motion in perovskites (perovskites are mixed electronic-ionic conductors), making perovskite solar cells with carbon coatings for water splitting to make solar fuels. This is about making perovskites more stable to help scale up their production. Her work has helped to position the University as somewhere of real solar energy expertise and has also helped to put the UK to the forefront of perovskite development. For more information on our guests and the University of Bath's Research with Impact Podcast please visit go.bath.ac.uk/research-with-impact or follow @uniofbath.

Science in Action
Bird flu: The global threat

Science in Action

Play Episode Listen Later Apr 13, 2023 31:45


H5N1, a highly pathogenic avian flu is racing across the world, and has infected multiple species, including wild and farmed birds, and mammals from cats to sea lions. What can be done to control it? Roland Pease talks to global experts about the dangers to animal and human health, and about the measures to bring the outbreak under control. Producer: Roland Pease Assistant producer: Sophie Ormiston (Photo: A government worker examines chicks for signs of bird flu infection at a poultry farm in Darul Imarah in Indonesia's Aceh province. Credit: Chaideer Mahyuddin)

The Science Hour
Human genome editing: Promise and Peril

The Science Hour

Play Episode Listen Later Mar 12, 2023 61:54 Very Popular


We meet experts at the Human Genome Editing Summit in London, seeking to cure genetic disease and ensure that it is safe and available to all. Roland Pease hears from Victoria Gray, the first person to be cured of the debilitating and life-shortening disease sickle cell anaemia by gene editing, and from the scientists making it possible. Also, the prospect of work to attempt gene rescue in fetuses before they are born. But the technology is expensive and complex. The question troubling the participants is to ensure people across the world can benefit from it, not just the rich and privileged. And what are the limitations of gene editing? Can it be made more effective, safer? And what of gene edits that will be inherited by future generations?

Science in Action
Human Genome Editing - Promise and Peril

Science in Action

Play Episode Listen Later Mar 9, 2023 34:57


Human Genome Editing: The team meet experts at the Human Genome Editing Summit in London, seeking to cure genetic disease and ensure that it's safe and available to all. Roland Pease hears from Victoria Gray, the first person to be cured of the debilitating and life-shortening disease sickle cell anaemia by gene editing, and from the scientists making it possible. Also, the prospect of work to attempt gene rescue in fetuses before they are born. But the technology is expensive and complex – the question troubling the participants is to ensure people across the world can benefit from it, not just the rich and privileged. And what are the limitations of gene editing? Can it be made more effective, safer? And what of gene edits that will be inherited by future generations?

Public lecture podcasts
Research with Impact with Roland Pease: How can we tackle preventable diseases?

Public lecture podcasts

Play Episode Listen Later Feb 28, 2023 29:55


Episode Three: How can we tackle preventable diseases? In Episode Three of the University of Bath's Research with Impact podcast, Roland Pease discusses preventable diseases with three of the University's world-leading experts, whose research focuses on improving health around the world. Professor Asel Sartbaeva – based in the Department of Chemistry and Centre for Sustainable and Circular Technologies – first joined the University in the Earth Sciences Department and went on to focus on the design and synthesis of zeolites and biomolecule. Asel's work on vaccine stability using silica aims to do away with the need for refrigeration of vaccines. Dr John Campbell – from the Department for Health – collaborates with Bath Royal United Hospital, and national and international collaborators, to investigate how exercise augments anti-cancer immunity. John is currently leading a Cancer Research UK Pioneer Award exploring the impact of exercise on blood cancer immunotherapies. Professor Harry Rutter – from the Department of Social & Policy Sciences – is a member of numerous influential research teams which work on issues affecting public health policy across the UK and beyond. A previous medical doctor, Harry founded the National Obesity Observatory and has a strong interest in promoting greater active travel. Most recently Harry has used his expertise and experiences in assessing public health responses to Covid-19. For more information on our guests and the University of Bath's Research with Impact Podcast please visit go.bath.ac.uk/research-with-impact or follow @uniofbath.

Science in Action
The James Webb Space Telescope: The first six months

Science in Action

Play Episode Listen Later Dec 29, 2022 32:56 Very Popular


Nasa's James Webb Space Telescope has produced amazing images, and amazing science, in its first five months. Roland Pease hears from one of the leading astronomers on the JWST programme, Dr Heidi Hammel, as well as other experts on what they are already learning about the first galaxies in the Universe, the birthplaces of stars, the strange behaviour of some other stars, and the first view of Neptune's rings in over 30 years. Producer: Roland Pease Assistant producer: Sophie Ormiston Image: An image from the James Webb Space Telescope (Credit: Nasa via PA)

Public lecture podcasts
Research with Impact with Roland Pease: How can we make big data work for society?

Public lecture podcasts

Play Episode Listen Later Dec 6, 2022 30:44


In Episode Two of the University of Bath's Research with Impact podcast, Roland Pease discusses the potential of big data for society with three of the University's world-leading experts, whose research focuses on big data and digitisation. Professor Chris Budd – based in the Department of Mathematical Sciences and Institute for Mathematical Innovation – creates and analyses mathematical models of the real world. His work utilises historical data, ONS statistics, and medical imagery to provide insight in the fields of weather, climate change, disease control, and medical diagnoses. Professor David Ellis – from the School of Management – is a computational social scientist whose work bridges the gap between psychology and data science. David's research explores behaviour in the digital age, and the psychological value and impacts of technology as it relates to privacy, security, health, and well-being. Professor Linda Newnes – of the Department of Mechanical Engineering - focuses on whole life value analysis (monetary, environmental and societal costs) from concept design through to the in-service and in-use phases. Linda is currently leading on a number of large cross University projects, including the Made Smarter Innovation: Centre for People-Led Digitalisation and the TRansdisciplinary ENgineering Design (TREND) research group. For more information on our guests and the University of Bath's Research with Impact Podcast please visit go.bath.ac.uk/research-with-impact or follow @uniofbath.

The Science Hour
The final moments of DART

The Science Hour

Play Episode Listen Later Oct 1, 2022 53:42 Very Popular


NASA's latest mission, DART hit the headlines this week after the space agency's satellite successfully collided with a far off asteroid. The mission acts as a demonstration of Earth's first planetary defence system. Jon Amos, one of BBC's Science correspondents, talks Roland through the final moments of the DART satellite. Although the collision was a success, we may have to wait a little longer before we know if the asteroid's trajectory has been altered… Simone Pirrotta, project manager at the Italian Space Agency, has more to add. His nifty camera system broke away 10 days before DART's collision, ensuring its own survival. This celestial drive by is guaranteed to provide scientific data to get excited about. Also this week, we visit the China Kadoorie Biobank. Twenty years in the making, it houses a collection of over half a million genetic samples, which might help identify links between our own genetic compositions and illness. Roland Pease visited them in Oxford to find out more. Finally, a new review describes the use of mercury by ancient Mayans. The metal is famous for its use across a plethora of civilizations throughout history. Andrea Sella from University College London, tells Roland how his favourite element underpins industrialisation across the ages and the globe. There are over 30,000 species of fish – that's more than all the species of amphibians, reptiles, birds and mammals combined. But despite the sheer diversity of life on Earth, we still tend to think of all fish in roughly the same way: with an oblong scaly body, a tail and pairs of fins. Why? And is that really the case? Crowdscience listener and pet fish-owner Lauria asked us to dive into the depths of this aquatic world to investigate why fish are shaped the way they are. Featuring fossils, flippers and plenty of fish, presenter Anand Jagatia makes a splash exploring the fascinating story of fish evolution, how they came to be such a different shape from mammals and even how some mammals have evolved to be more like fish. Image: An illustration of the DART spacecraft headed toward its target Credit: NASA/John Hopkins APL

Science in Action
The final moments of DART

Science in Action

Play Episode Listen Later Sep 29, 2022 26:28 Very Popular


NASA's latest mission, DART hit the headlines this week after the space agency's satellite successfully collided with a far off asteroid. The mission acts as a demonstration of Earth's first planetary defence system. Jon Amos, one of BBC's Science correspondents, talks Roland through the final moments of the DART satellite. Although the collision was a success, we may have to wait a little longer before we know if the asteroid's trajectory has been altered… Simone Pirrotta, project manager at the Italian Space Agency, has more to add. His nifty camera system broke away 10 days before DART's collision, ensuring its own survival. This celestial drive by is guaranteed to provide scientific data to get excited about. Also this week, we visit the China Kadoorie Biobank. Twenty years in the making, it houses a collection of over half a million genetic samples, which might help identify links between our own genetic compositions and illness. Roland Pease visited them in Oxford to find out more. Finally, a new review describes the use of mercury by ancient Mayans. The metal is famous for its use across a plethora of civilizations throughout history. Andrea Sella from University College London, tells Roland how his favourite element underpins industrialisation across the ages and the globe. Image: An illustration of the DART spacecraft headed toward its target Credit: NASA/John Hopkins APL Presenter: Roland Pease Producer: Harrison Lewis, Robbie Wojciechowski

The Science Hour
Synthetic mouse embryos with brains and hearts

The Science Hour

Play Episode Listen Later Aug 7, 2022 56:40 Very Popular


This week two research groups announced that they have made synthetic mouse embryos that developed brains and beating hearts in the test tube, starting only with embryonic stem cells. No sperm and eggs were involved. Previously, embryos created this way have never got beyond the stage of being a tiny ball of cells. These embryos grew and developed organs through 8 days – more than a third of the way through the gestation period for a mouse. Roland Pease talks to the leader of one of the teams, developmental biologist Magdalena Zernicka-Goetz of Cambridge University and Caltech about how and why they did this, and the ethical issues around this research. Also in the programme: the latest research on how we spread the SARS-CoV-2 virus when we breathe. Infectious disease researcher Kristen Coleman of the University of Maryland tells us about her experiments that have measured the amounts of virus in the tiny aerosol particles emanating from the airways of recently infected people. The results underscore the value of mask-wearing and effective ventilation in buildings. We also hear about new approaches to vaccines against the virus – Kevin Ng of the Crick Institute in London talks about the possibility of a universal coronavirus vaccine based on his research, and immunologist Akiko Iwasaki of Yale University extolls the advantages of nasal vaccines against SARS-CoV-2. From dumping raw sewage into rivers to littering the streets with our trash, humans don't have a great track record when it comes to dealing with our waste. It's something that CrowdScience listener and civil engineer Marc has noticed: he wonders if humans are particularly prone to messing up our surroundings, while other species are instinctively more hygienic and well-organised. Are we, by nature, really less clean and tidy than other animals? Farming and technology have allowed us to live more densely and generate more rubbish - maybe our cleaning instincts just aren't up to the vast quantities of waste we spew out? CrowdScience digs into the past to see if early human rubbish heaps can turn up any answers. We follow a sewer down to the River Thames to hear about The Great Stink of Victorian London; turn to ants for housekeeping inspiration; and find out how to raise hygiene standards by tapping into our feelings of disgust and our desire to follow rules. (Image: Stem cell built mouse embryo at 8 days. Credit: Zernicka-Goetz Lab)

Science in Action
Synthetic mouse embryos with brains and hearts

Science in Action

Play Episode Listen Later Aug 4, 2022 29:38


This week two research groups announced that they have made synthetic mouse embryos that developed brains and beating hearts in the test tube, starting only with embryonic stem cells. No sperm and eggs were involved. Previously, embryos created this way have never got beyond the stage of being a tiny ball of cells. These embryos grew and developed organs through 8 days – more than a third of the way through the gestation period for a mouse. Roland Pease talks to the leader of one of the teams, developmental biologist Magdalena Zernicka-Goetz of Cambridge University and Caltech about how and why they did this, and the ethical issues around this research. Also in the programme: the latest research on how we spread the SARS-CoV-2 virus when we breathe. Infectious disease researcher Kristen Coleman of the University of Maryland tells us about her experiments that have measured the amounts of virus in the tiny aerosol particles emanating from the airways of recently infected people. The results underscore the value of mask-wearing and effective ventilation in buildings. We also hear about new approaches to vaccines against the virus – Kevin Ng of the Crick Institute in London talks about the possibility of a universal coronavirus vaccine based on his research, and immunologist Akiko Iwasaki of Yale University extolls the advantages of nasal vaccines against SARS-CoV-2. (Image: Stem cell built mouse embryo at 8 days. Credit: Zernicka-Goetz Lab) Presenter: Roland Pease Producer: Andrew Luck-Baker

The Science Hour
The first galaxies at the universe's dawn

The Science Hour

Play Episode Listen Later Jul 30, 2022 54:59 Very Popular


n the last week, teams of astronomers have rushed to report ever deeper views of the universe thanks to the James Webb Space Telescope. These are galaxies of stars more than 13.5 billion light years from us and we see them as they were when the universe was in its infancy, less than 300 million years after the Big Bang. As University of Texas astronomer Steve Finkelstein tell us, there are some real surprises in these glimpses of the cosmic dawn. The super-distant galaxy that Steve's group has identified is named after his daughter Maisie. Also in the programme: a 550 million year old fossil which is much the oldest representative of a large group of animals still with us today. The early jellyfish relative lived at a time known as the Ediacaran period when all other known complex organisms were weird, alien-looking lifeforms with no surviving descendants. Roland Pease talks palaeontologist Frankie Dunn at the University of Oxford who's led the study of Auroralumina attenboroughii. Did the cultural invention of romantic kissing five thousand years ago lead to the spread of today's dominant strain of the cold sore virus (Herpes simplex 1) across Europe and Asia? That's the hypothesis of a team of virologists and ancient DNA experts who've been studying viral DNA remnants extracted from four very old teeth. Cambridge University's Charlotte Houldcroft explains the reasoning. And, If a tree falls in a forest, and no-one is there to hear it, does it make a sound? This is an age-old debate that listener Richard and his family have been arguing about for years. Can CrowdScience settle it once and for all? Caroline Steel speaks to experts in hearing, biology, philosophy, physics and sound design, which takes her to some unexpected places. Professor Stefan Bleek is an expert in psychoacoustics who says that sounds only exist in our heads. Dr Eleanor Knox and Dr Bryan Roberts are philosophers that make her question if anything exists outside our own perception. Professor Lilach Hadany wonders if it's limited to humans and animals - could other plants hear the falling tree too? And Mat Eric Hart is a sound designer who says that sound is subjective – it's always tangled up with our own interpretations. Things get truly weird as we delve into the strange implications of quantum physics. If there is such a thing as reality, doesn't it change when we're there to observe it? Does the tree even fall if we aren't there? Image: Maisie's Galaxy aka CEERSJ141946.35-525632.8. Credit: CEERS Collaboration

Over to You
Discovering the Large Hadron Collider

Over to You

Play Episode Listen Later Jul 30, 2022 9:00


The Discovery programme recently returned to the Large Hadron Collider under the Swiss-French border, 10 years after the discovery of the Higgs Boson particle. But can you really make complex physics accessible to a general audience? The show's presenter and series producer Roland Pease answers your questions. Plus, how a simple Ukrainian piano Tweet by the BBC's Steve Rosenberg in Moscow captivated listeners. Presenter: Rajan Datar. Producer: Howard Shannon A Whistledown production for BBC World Service

Science in Action
The first galaxies at the universe's dawn

Science in Action

Play Episode Listen Later Jul 28, 2022 27:44


In the last week, teams of astronomers have rushed to report ever deeper views of the universe thanks to the James Webb Space Telescope. These are galaxies of stars more than 13.5 billion light years from us and we see them as they were when the universe was in its infancy, less than 300 million years after the Big Bang. As University of Texas astronomer Steve Finkelstein tell us, there are some real surprises in these glimpses of the cosmic dawn. The super-distant galaxy that Steve's group has identified is named after his daughter Maisie. Also in the programme: a 550 million year old fossil which is much the oldest representative of a large group of animals still with us today. The early jellyfish relative lived at a time known as the Ediacaran period when all other known complex organisms were weird, alien-looking lifeforms with no surviving descendants. Roland Pease talks palaeontologist Frankie Dunn at the University of Oxford who's led the study of Auroralumina attenboroughii. Did the cultural invention of romantic kissing five thousand years ago lead to the spread of today's dominant strain of the cold sore virus (Herpes simplex 1) across Europe and Asia? That's the hypothesis of a team of virologists and ancient DNA experts who've been studying viral DNA remnants extracted from four very old teeth. Cambridge University's Charlotte Houldcroft explains the reasoning. Image: Maisie's Galaxy aka CEERSJ141946.35-525632.8. Credit: CEERS Collaboration Presenter: Roland Pease Producer: Andrew Luck-Baker

Discovery
The mysterious particles of physics, part 3

Discovery

Play Episode Listen Later Jul 18, 2022 27:36 Very Popular


The smaller the thing you look at, the bigger the microscope you need to use. That's why the circular Large Hadron Collider at CERN, where they discovered the Higgs boson is 27 kilometres long, and its detectors tens of metres across. But to dig deeper still into the secrets of the Universe, they're already talking about another machine 4 times bigger, to be built by the middle of the century. Roland Pease asks if it's worth it.

The Science Hour
First images from the James Webb Space Telescope

The Science Hour

Play Episode Listen Later Jul 16, 2022 63:10 Very Popular


Roland Pease talks to two astronomers who began working on the James Webb Space Telescope more than two decades ago and have now seen the first spectacular results of their labours. Marcia Rieke of the University of Arizona and JWST's senior project scientist John Mather discuss the highlights of the first four images. Also in the programme, geologists discover precisely where on the Red Planet the most ancient Martian meteorite came from - we speak to Anthony Lagain whose detective work identified the crater from which the rock was ejected into space. And what causes vast areas of the Indian Ocean to glow with strange light - a rare and mysterious phenomenon known as 'milky seas'? The world is a step closer to understanding this centuries' old maritime enigma thanks to the crew of a yacht sailing south of Java, atmospheric scientist Steven Miller and marine microbiologist Kenneth Nealson. We are running out of ammunition against certain infections, as bacteria increasingly evade the antibiotics we've relied on for nearly a century. Could bacteriophages – viruses that hunt and kill bacteria – be part of the solution? In 2019, CrowdScience travelled to Georgia where bacteriophages, also known as phages, have been used for nearly a hundred years to treat illnesses ranging from a sore throat to cholera. Here we met the scientists who have kept rare phages safe for decades, and are constantly on the look-out for new ones. Phages are fussy eaters: a specific phage will happily chew on one bacteria but ignore another, so hunting down the right one for each infection is vital. Since then, we've lived through a pandemic, the medical landscape has been transformed, and interest in bacteriophages as a treatment option is growing throughout the world. We turn to microbiologist Professor Martha Clokie for updates, including the answer to listener Garry's question: could phages help in the fight against Covid-19?

Science in Action
First images from the James Webb Space Telescope

Science in Action

Play Episode Listen Later Jul 14, 2022 31:57


Roland Pease talks to two astronomers who began working on the James Webb Space Telescope more than two decades ago and have now seen the first spectacular results of their labours. Marcia Rieke of the University of Arizona and JWST's senior project scientist John Mather discuss the highlights of the first four images. Also in the programme, geologists discover precisely where on the Red Planet the most ancient Martian meteorite came from - we speak to Anthony Lagain whose detective work identified the crater from which the rock was ejected into space. And what causes vast areas of the Indian Ocean to glow with strange light - a rare and mysterious phenomenon known as 'milky seas'? The world is a step closer to understanding this centuries' old maritime enigma thanks to the crew of a yacht sailing south of Java, atmospheric scientist Steven Miller and marine microbiologist Kenneth Nealson. Image: The Southern Ring Nebula Credit: NASA/STScI Presenter: Roland Pease Producer: Andrew Luck-Baker

Discovery
The mysterious particles of physics, part 2

Discovery

Play Episode Listen Later Jul 11, 2022 33:23 Very Popular


Episode 2: Lost in the Dark Physics is getting a good understanding of atoms, but embarrassingly they're only a minor part of the Universe. Far more of it is made of something heavy and dark, so-called dark matter. The scientists who discovered the Higgs boson ten years ago thought they'd also create dark matter in the underground atom smasher at CERN. But they haven't seen it yet. Roland Pease joins them as they redouble their efforts at the upgraded Large Hadron Collider, and travels to Boulby Underground Laboratory inside Britain's deepest mine, where subterranean telescopes hope to see dark matter streaming through the Galaxy.

Discovery
The Mysterious Particles of Physics (1/3)

Discovery

Play Episode Listen Later Jul 4, 2022 30:11


The machine that discovered the Higgs Boson 10 years ago is about to restart after a massive upgrade, to dig deeper into the heart of matter and the nature of the Universe. Roland Pease returns to CERN's 27-kilometre Large Hadron Collider (LHC) dug deeper under the Swiss-French border to meet the scientists wondering why the Universe is the way it is. He hears why the Nobel-prize winning discovery of the “Higgs Particle” remains a cornerstone of the current understanding of the nature of matter; why the search for “dark matter” – 25% of the cosmos - is proving to be so hard; and CERN's plans for an atom smasher 4 times as big to be running by the middle of the century.

The Science Hour
Extreme heat death risk in Latin America

The Science Hour

Play Episode Listen Later Jul 3, 2022 63:30 Very Popular


A new analysis of deaths in cities across Latin America suggests rising global temperatures could lead to large numbers of deaths in the region and elsewhere in the world. Even a 1-degree rise in extreme heat can add 6% to the risk of dying. Lead researcher Josiah Kephart at Drexel University tells Roland Pease the lessons from Latin America should apply to cities across the global south. Brazilian ecologist Andreas Meyer talks about the troubling prospects for the health of ecosystems, particularly in tropical regions, if the world does not cut its fossil fuel emissions hard and fast in the next few years. In the USA, a team of engineers and neurosurgeons are developing a radical new approach for targeted pain relief – in the first instance, for patients recovering from surgery. It's a flexible implant that wraps around a nerve and cools it to prevent it from transmitting pain signals. What's more, says bioengineer John Rogers, the implant is made of a material designed to have dissolved safely into the body by the time its pain-killing work is done. Geologist Bob Hazen has spent more than a decade producing a new classification system for the 5,700 minerals known to exist on the Earth. It improves on the pre-existing scheme by taking into account the myriad ways that many minerals have come into being. He tells Roland that this new way of categorising minerals lays bare a 4.5 billion-year history of remarkable chemical and biological creativity. And, Hair is an important part of our identities – straight, frizzy, long, not there at all – and our efforts to keep it styled and clean have created an $80 billion hair care industry. Many products offer to improve the life of the stuff on our heads, but isn't it all just dead protein? CrowdScience listener Toria wants to know what 'healthy' hair really means. To untangle the science behind hair, we zoom in to see how hair grows from the follicles in our scalp and explore how the hair growth process will change over our lifetimes. Changes in our hair and disorders affecting the scalp can often have emotional impacts on our lives, as presenter Marnie Chesterton learns from a dermatologist who specialises in hair issues. Having been on a journey with her own hair in recent years following chemotherapy, Marnie is ready for a new 'do and ventures to the hair salon to find out about the health of her own hair. Meanwhile, another CrowdScience listener, Lucy, wonders why humans lost hair (or fur) on most of our bodies when most other mammals are covered in the stuff. A biological anthropologist who studies not only why hair became concentrated on our heads, but also why there's so much diversity in hair types across humans unpacks the evolutionary benefits. With all these different hair types, we ask: does different hair need different care? And when it comes to shampoo, conditioner, washing, blowdrying and dyeing – what should we be doing to keep our hair structure sound? As we learn about this strange nonliving feature of our bodies, Marnie finds a new appreciation for the "dead strands of protein sticking out of our skin". And with listener Toria's help and advice, she also finds a new shade for her chemo-curled locks. (Image: Rio de Janeiro City. Credit: Pintai Suchachaisri/Getty Images)

Science in Action
Extreme heat death risk in Latin America

Science in Action

Play Episode Listen Later Jun 30, 2022 32:05


A new analysis of deaths in cities across Latin America suggests rising global temperatures could lead to large numbers of deaths in the region and elsewhere in the world. Even a 1-degree rise in extreme heat can add 6% to the risk of dying. Lead researcher Josiah Kephart at Drexel University tells Roland Pease the lessons from Latin America should apply to cities across the global south. Brazilian ecologist Andreas Meyer talks about the troubling prospects for the health of ecosystems, particularly in tropical regions, if the world does not cut its fossil fuel emissions hard and fast in the next few years. In the USA, a team of engineers and neurosurgeons are developing a radical new approach for targeted pain relief – in the first instance, for patients recovering from surgery. It's a flexible implant that wraps around a nerve and cools it to prevent it from transmitting pain signals. What's more, says bioengineer John Rogers, the implant is made of a material designed to have dissolved safely into the body by the time its pain-killing work is done. Geologist Bob Hazen has spent more than a decade producing a new classification system for the 5,700 minerals known to exist on the Earth. It improves on the pre-existing scheme by taking into account the myriad ways that many minerals have come into being. He tells Roland that this new way of categorising minerals lays bare a 4.5 billion-year history of remarkable chemical and biological creativity. (Image: Rio de Janeiro City. Credit: Pintai Suchachaisri/Getty Images) Presenter: Roland Pease Producer: Andrew Luck-Baker

The Science Hour
Monster microbe

The Science Hour

Play Episode Listen Later Jun 26, 2022 69:01 Very Popular


Researchers have discovered a species of bacteria which dwarfs all others by thousands of times. Normally you need a microscope to see single-celled bacteria, but Thiomargarita magnifica is the length and width of an eyelash. It's been found growing in mangrove swamps in the Caribbean. Roland Pease talks to Jean Marie Volland about what makes this Godzilla of the microbial world extra-special. Also in the programme, a new study published in the journal Nature has discovered that women scientists are less likely than their male peers to be credited for their contributions to research projects. Roland discusses the findings with the study leader Julia Lane of New York University and nanoscientist Shobhana Narasimhan in Bangalore. We also find out about the oldest evidence for wildfires on the planet which raged across the land 430 million years ago, with palaeobotanist Ian Glasspool. And Edinburgh University vertebrate palaeontologist Steve Brusatte talks about some of the evolutionary wonders in his new book The Rise and Reign of the Mammals. Death is inevitable, though many of us would rather not dwell on it. For those with a terminal illness, however, the end of life is clearly a more pressing reality. CrowdScience listener Sam has known for a while that her illness is terminal, and by now she's got used to the idea. But she finds many friends and family would rather avoid the subject at all costs; they don't want to acknowledge what's happening until it's all over. She's wondering if there's a way to lighten up the topic of her approaching death, and create the openness she craves. If we could learn to be more accepting of illness and dying, the end of life could be a more positive experience for all involved. So how can we face up to the impending death of a loved one, and best support that person in the process? In search of answers, we talk a clinical psychologist about death anxiety, visit a death café, and learn about a scheme in India where whole communities are trained in caring for people at the end of life. (Image: Thiomargarita magnifica. © The Regents of the University of California, Lawrence Berkeley National Laboratory) Presenter: Roland Pease Producer: Andrew Luck-Baker

Science in Action
Monster microbe

Science in Action

Play Episode Listen Later Jun 23, 2022 34:11


Researchers have discovered a species of bacteria which dwarfs all others by thousands of times. Normally you need a microscope to see single-celled bacteria, but Thiomargarita magnifica is the length and width of an eyelash. It's been found growing in mangrove swamps in the Caribbean. Roland Pease talks to Jean Marie Volland about what makes this Godzilla of the microbial world extra-special. Also in the programme, a new study published in the journal Nature has discovered that women scientists are less likely than their male peers to be credited for their contributions to research projects. Roland discusses the findings with the study leader Julia Lane of New York University and nanoscientist Shobhana Narasimhan in Bangalore. We also find out about the oldest evidence for wildfires on the planet which raged across the land 430 million years ago, with palaeobotanist Ian Glasspool. And Edinburgh University vertebrate palaeontologist Steve Brusatte talks about some of the evolutionary wonders in his new book The Rise and Reign of the Mammals. (Image: Thiomargarita magnifica. © The Regents of the University of California, Lawrence Berkeley National Laboratory) Presenter: Roland Pease Producer: Andrew Luck-Baker

Public lecture podcasts
Research with Impact with Roland Pease: 'How do we get to net zero?'

Public lecture podcasts

Play Episode Listen Later Jun 22, 2022 31:56


In Episode One of the University of Bath's Research with Impact podcast, Roland Pease discusses the route to net zero with three of the University's world-leading experts, whose research focuses on aspects of the climate crisis. Professor Lorraine Whitmarsh – from the Department of Psychology – is Director of the Centre for Climate Change and Social Transformations (CAST), member of the Climate Crisis Advisory Group and was an expert lead for Climate Assembly UK. She also recently advised for Netflix's climate change parody ‘Don't Look Up'. Professor Marcelle McManus – part of the Department of Mechanical Engineering – specialises in life cycle assessment, sustainable systems, renewable technologies and bioenergy. Marcelle is a Research Director of the Industrial Decarbonisation Research and Innovation Centre and is also one of the Directors of the Centre for Sustainable and Circular Technologies. Professor Ania Zalewska - one of the School of Management's foremost academics - is an expert in financial regulation and reform, in particular the pensions industry; green finance and the financial challenges around climate change; and market and investment risk. Ania has a large following on LinkedIn, where she engages with academics and industry experts. For more information on our guests and the University of Bath's Research with Impact Podcast please visit go.bath.ac.uk/research-with-impact or follow @uniofbath.

Public lecture podcasts
Research with Impact Podcast - with Roland Pease (trailer)

Public lecture podcasts

Play Episode Listen Later Jun 21, 2022 0:58


Join acclaimed science journalist and broadcaster, Roland Pease, as he meets nine researchers from the University of Bath whose expertise spans the environment, the digital age, and preventable diseases, looking for answers to three fundamental questions: • How do we get to net zero carbon? • How can we make big data work for society? • And, how can we reduce the number of people still dying from preventable diseases? For more information about guests and how research from the University of Bath is having an impact please visit go.bath.ac.uk/research-with-impact and follow @uniofbath.

The Science Hour
Body scan reveals HIV's hideouts

The Science Hour

Play Episode Listen Later Jun 11, 2022 60:47 Very Popular


Researchers have developed a medical imaging technique which reveals where in the body HIV lies hidden, even when people have their infection well controlled by antiviral drugs. The team at the University of California, San Francisco hope this will lead to better treatments and even cures for HIV. As Timothy Henrich told us, they are also going to use the technique to investigate the notion that Long Covid is caused by the coronavirus persisting deep in the body's tissues. Also in the programme, Roland Pease reports from the vast particle accelerator in Switzerland where the famous Higgs particle was discovered ten years ago. The scientists there are preparing to begin experiments with an upgraded Large Hadron Collider to learn more about the particle and the fundamental nature of the Universe. Roland also talks to Frank Close, physicist and author of 'Elusive' - a new biography of Peter Higgs, a scientist as elusive as the particle named after him. Finally an international team of archaeologists have revised the ancient history of the chicken, with a new programme of radiocarbon dating and analysis of buried bird bones. Humanity's relationship with the bird began much more recently than some researchers have suggested. Naomi Sykes of Exeter University and Greger Larson of Oxford University tell Roland when, where and how the domestication began and how the birds spread from Southeast Asia to the rest of the world. And, Humans can walk for miles, solve problems and form complex relationships on the energy provided by three meals a day. That's a lot of output for a fairly modest input. Listener Charlotte from the UK wants to know: how are we so efficient? And how does human efficiency compare to that of machines? CrowdScience presenter Marnie Chesterton pits her energetic wits against everything from cars to wheelchairs to find out how she shapes up. Cars can travel many hundreds of kilometres a day if you give them a couple of tanks of fuel. But the only fuel Marnie needs to walk to work is a cup of coffee. She gets experts to help her work out who does the most efficient job. Marnie also explores whether humans are born equal when it comes to fuel efficiency. Does the energy from one banana get converted into the same amount of movement from person to person? And how does she compare to an Olympic athlete? Marnie gets put through her paces to find out how efficient she really is. Image: VRCPET body scan reveals HIV's hideouts Credit: Timothy Henrich / University of California, San Francisco

BBC Inside Science
Running Rings Around Matter

BBC Inside Science

Play Episode Listen Later Jun 9, 2022 28:10 Very Popular


Astronomers have captured the first image of Sagittarius A*, the gargantuan black hole at the centre of our galaxy. Dr Ziri Younsi, University College London, shares what it took to capture a picture of a supermassive black hole that is 26,000 light-years away and from which (almost) nothing, not even light, can escape. The world's largest and most powerful particle accelerator, the Large Hadron Collider, is restarting after three years of upgrades. Roland Pease visits the European Particle Physics Laboratory, CERN, to see how things are going, and looks back on some of the team's past successes. Also, how do you investigate the mysterious deaths of the world's biggest fish when their bodies sink without trace? That's the quandary facing marine scientists who've been trying to figure out what exactly is killing whale sharks. Freya Womersley, UK Marine Biological Association, shares how satellite tracking technology is helping us solve the mystery. And finally, what's in a name? As our inventory of Earth's biodiversity progresses, the number of species given a Latin name is also growing. So, where do scientists find their naming inspiration? In Royal Society Proceedings B this week, an analysis of nearly 3,000 parasitic worm species uncovered some intriguing patterns and worrying biases. Samara Linton reports. Presenter Victoria Gill Produced by Alex Mansfield and Samara Linton

Science in Action
Body scan reveals HIV's hideouts

Science in Action

Play Episode Listen Later Jun 9, 2022 29:43


Researchers have developed a medical imaging technique which reveals where in the body HIV lies hidden, even when people have their infection well controlled by antiviral drugs. The team at the University of California, San Francisco hope this will lead to better treatments and even cures for HIV. As Timothy Henrich told us, they are also going to use the technique to investigate the notion that Long Covid is caused by the coronavirus persisting deep in the body's tissues. Also in the programme, Roland Pease reports from the vast particle accelerator in Switzerland where the famous Higgs particle was discovered ten years ago. The scientists there are preparing to begin experiments with an upgraded Large Hadron Collider to learn more about the particle and the fundamental nature of the Universe. Roland also talks to Frank Close, physicist and author of 'Elusive' - a new biography of Peter Higgs, a scientist as elusive as the particle named after him. Finally an international team of archaeologists have revised the ancient history of the chicken, with a new programme of radiocarbon dating and analysis of buried bird bones. Humanity's relationship with the bird began much more recently than some researchers have suggested. Naomi Sykes of Exeter University and Greger Larson of Oxford University tell Roland when, where and how the domestication began and how the birds spread from Southeast Asia to the rest of the world. Image: VRCPET body scan reveals HIV's hideouts Credit: Timothy Henrich / University of California, San Francisco Presenter: Roland Pease Producer: Andrew Luck-Baker

The Science Hour
Heat death by volcano and other stories

The Science Hour

Play Episode Listen Later May 29, 2022 56:47 Very Popular


This week Science in Action comes from a vast gathering of earth scientists in Vienna, at the general assembly of the European Geosciences Union. Roland Pease hears the latest insights into the cataclysmic eruption of Hunga Tonga in the Pacific ocean from volcanologist Shane Cronin of the University of Auckland. He also talks to NASA's Michael Way about how the planet Venus might have acquired its hellish super-greenhouse atmosphere, and how the same thing could happen to planet Earth. There's intriguing research from geologist John Tarduno of the University of Rochester that hints of a link between the ups and downs of the Earth's magnetic field and the evolutionary history of animals. Fraser Lott of the UK's Hadley Centre explains his ideas for calculating an individual person's responsibility for climate change-driven extreme weather events. And ... On Crowd Science, why can't I find gold in my back yard? If you go outside with a spade and start digging, the chances are you won't find any gold. You might get lucky or just happen to live in a place where people have been finding gold for centuries. But for the most part, there'll be none. But why is that? Why do metals and minerals show up in some places and not others? It's a question that's been bothering CrowdScience listener Martijn in the Netherlands, who has noticed the physical effects of mining in various different places while on his travels. It's also a really important question for the future – specific elements are crucial to modern technology and renewable energy, and we need to find them somewhere. Marnie Chesterton heads off on a hunt for answers, starting in a Scottish river where gold can sometimes be found. But why is it there, and how did it get there? Marnie goes on a journey through the inner workings of Earth's geology and the upheaval that happens beneath our feet to produce a deposit that's worth mining. On the way she discovers shimmering pools of lithium amongst the arid beauty of the Atacama Desert, meets researchers who are blasting rocks with lasers and melting them with a flame that's hotter than the surface of the sun, and heads to the bottom of the ocean to encounter strange potato-sized lumps containing every single element on Earth. And maybe, just maybe, she'll also find gold. Image: Multi-beam sonar map of Hunga Tonga volcano post-eruption Credit: Shane Cronin/Uni of Auckland/Tonga Geological Services Presented by Roland Pease and Marnie Chesterton Report by Jane Chambers Produced by Andrew Luck-Baker and Ben Motley

Science in Action
Heat death by volcano and other stories

Science in Action

Play Episode Listen Later May 26, 2022 29:47


Science in Action this week comes from a vast gathering of earth scientists in Vienna, at the general assembly of the European Geosciences Union. Roland Pease hears the latest insights into the cataclysmic eruption of Hunga Tonga in the Pacific ocean from volcanologist Shane Cronin of the University of Auckland. He also talks to NASA's Michael Way about how the planet Venus might have acquired its hellish super-greenhouse atmosphere, and how the same thing could happen to planet Earth. There's intriguing research from geologist John Tarduno of the University of Rochester that hints of a link between the ups and downs of the Earth's magnetic field and the evolutionary history of animals. Fraser Lott of the UK's Hadley Centre explains his ideas for calculating an individual person's responsibility for climate change-driven extreme weather events. Image: Multi-beam sonar map of Hunga Tonga volcano post-eruption Credit: Shane Cronin/Uni of Auckland/Tonga Geological Services Presenter: Roland Pease Producer: Andrew Luck-Baker

The Science Hour
Portrait of the monster black hole at our galaxy's heart

The Science Hour

Play Episode Listen Later May 15, 2022 64:36


The heaviest thing in the Galaxy has now been imaged by the biggest telescope on Earth. This is Sagittarius A*, the supermassive black hole at the centre of our Galaxy – a gas and star-consuming object, a 4 million times the mass of the Sun. The Event Horizon Telescope is not one device but a consortium of radio telescopes ranging from the South Pole to the Arctic Circle. Their combined data allowed astronomers to focus in on this extreme object for the first time. Astronomer Ziri Younsi from University College London talks to Roland Pease about the orange doughnut image causing all the excitement. Also in the programme… Climatologist Chris Funk talks about the role of La Niña and climate change in the record-breaking two year drought that continues to threaten the lives and livelihoods of millions of people in East Africa. Was a pig virus to blame for the death of the first patient to receive a pig heart transplant? We talk to the surgeon and scientist at the University of Maryland School of Medicine who led the historic animal to human transplant operation this year. How easy will it be to grow plants in lunar soil on future moon bases? Plant biologist Anna Lisa Paul has been testing the question in her lab at the University of Florida, Gainesville, with cress seeds and lunar regolith collected by the Apollo missions. And…. Does photographic memory exist? Most people are great at remembering key points from important events in their lives, while the finer details - such as the colour of the table cloth in your favourite restaurant or the song playing on the radio while you brushed your teeth - are forgotten. But some people seem to have the power to remember events, documents or landscapes with almost perfect recall, which is widely referred to as having a photographic memory. CrowdScience listeners Tracy and Michael want to know if photographic memory actually exists and if not, what are the memory processes that allow people to remember certain details so much better than others? Putting her own memory skills to the test along the way, presenter Marnie Chesterton sets out to investigate just what's happening inside our brains when we use our memories, the importance of being able to forget and why some people have better memories than others. Photo: First image of Sgr A*, the supermassive black hole at the centre of our galaxy Credit: EHT Collaboration, Southern European Observatory Presenter: Roland Pease and Marnie Chesterton Producer: Andrew Luck-Baker and Hannah Fisher

Science in Action
Portrait of the monster black hole at our galaxy's heart

Science in Action

Play Episode Listen Later May 12, 2022 29:22


The heaviest thing in the Galaxy has now been imaged by the biggest telescope on Earth. This is Sagittarius A*, the supermassive black hole at the centre of our Galaxy – a gas and star-consuming object, a 4 million times the mass of the Sun. The Event Horizon Telescope is not one device but a consortium of radio telescopes ranging from the South Pole to the Arctic Circle. Their combined data allowed astronomers to focus in on this extreme object for the first time. Astronomer Ziri Younsi from University College London talks to Roland Pease about the orange doughnut image causing all the excitement. Also in the programme… Climatologist Chris Funk talks about the role of La Niña and climate change in the record-breaking two year drought that continues to threaten the lives and livelihoods of millions of people in East Africa. Was a pig virus to blame for the death of the first patient to receive a pig heart transplant? We talk to the surgeon and scientist at the University of Maryland School of Medicine who led the historic animal to human transplant operation this year. How easy will it be to grow plants in lunar soil on future moon bases? Plant biologist Anna Lisa Paul has been testing the question in her lab at the University of Florida, Gainesville, with cress seeds and lunar regolith collected by the Apollo missions. Photo: First image of Sgr A*, the supermassive black hole at the centre of our galaxy Credit: EHT Collaboration, Southern European Observatory Presenter: Roland Pease Producer: Andrew Luck-Baker

The Science Hour
Mekong Delta will sink beneath the sea by 2100

The Science Hour

Play Episode Listen Later May 8, 2022 61:06 Very Popular


The Mekong Delta is home to 17 million people and is Vietnam's most productive agricultural region. An international group of scientists warn this week that almost all of the low lying delta will have sunk beneath the sea within 80 years without international action. Its disappearance is the result of both sea level rise and developments such as dams and sand mining, as Matt Kondolf of the University of California, Berkeley explains to Roland Pease. Also in the programme: Seismologist Laura Emert on using the rumbling of traffic in Mexico City to monitor earthquake hazards. Mars-shaking Marsquakes – recent record-breaking quakes on Mars explained by seismologist Anna Horleston of Bristol University. A record-breaking high jumping robot designed by mechanical engineer and roboticist Elliot Hawkes which is so light it can access any terrain, perhaps even the moon. And gene editing…. Humans now have the ability to directly change their DNA and gene-editing tool CRISPR has led to a new era in gene-editing. CrowdScience listener ‘Bones' wants to know how gene-editing is currently being used and what might be possible in the future. Gene-editing offers huge opportunities for the prevention and treatment of human diseases, and trials are currently underway in a wide range of diseases like sickle cell anaemia. CrowdScience presenter Caroline Steel finds out about some of the most promising work tackling disease before turning to consider the possibilities of using gene editing for non-medical changes. Will we be able to extend human longevity, swap our eye colour or enhance athletic performance? And even if we can do all these things, should we? As scientists push the boundaries of gene-editing and some people are DIY experimenting on themselves with CRISPR, we discuss the practical and ethical challenges facing this promising but potentially perilous area of science. Photo: Mekong River in Kampong Cham, Cambodia Credit: Muaz Jaffar/EyeEm/Getty Images Presenters: Roland Pease and Caroline Steel Producers: Andrew Luck-Baker and Melanie Brown

The Science Hour
The Indian subcontinent's record-breaking heatwave

The Science Hour

Play Episode Listen Later May 1, 2022 65:55 Very Popular


Deadly heat has been building over the Indian sub-continent for weeks and this week reached crisis levels. India experienced its hottest March on record and temperatures over 40 degrees Celsius (and in some places approaching 50 degrees) are making it almost impossible for 1.4 billion people to work. It's damaging crops and it's just what climate scientists have been warning about. Roland Pease talks to Vimal Mishra of the Indian Institute of Technology in Gandhinagar about the impact and causes of the unprecedented heatwave. What could be behind the incidence of hepatitis in young children around the world in recent months? Ordinarily, liver disease in childhood is extremely rare. Could a virus normally associated with colds be responsible or is the Covid virus involved? Roland Pease talks to virologist William Irving of Nottingham University. Also in the programme: How climate change is increasing the likelihood of animal viruses jumping the species barrier to humans with global change modeller Colin Carlson of Georgetown University. Myths about the personalities of dog breeds are exploded with new research by Elinor Karlsson of the University of Massachusetts Medical School. And how do we stay up when we ride a bicycle? Lots of us can do it without even thinking about it, but probably very few of us can say exactly HOW we do it. Well, CrowdScience listener Arif and his children Maryam and Mohammed from India want to understand what's going on in our heads when we go for a cycle, and how we learn to do it in the first place. Marnie Chesterton is on the case, tracking down a neuroscientists studying how our brains and bodies work together to keep us balanced whether we're walking or trying to ride a bicycle. She learns about the quirks of bicycle engineering from researchers in the Netherlands who are part of a lab entirely devoted to answering this question. In the process falling off of some unusual bicycles and uncovering the surprising truth that physics might not yet have a proper answer. And we peer deeper into our brains to find out why some memories last longer than others, whether some people can learn quicker than others and the best way to learn a new skill. (Photo: Woman cooling herself in India heatwave Credit: Debajyoti Chakraborty/NurPhoto via Getty Images) Presenters: Roland Pease and Marnie Chesterton Producers: Andrew Luck-Baker and Emily Bird for BBC World Service

Science in Action
The Indian subcontinent's record-breaking heatwave

Science in Action

Play Episode Listen Later Apr 28, 2022 31:16


Deadly heat has been building over the Indian sub-continent for weeks and this week reached crisis levels. India experienced its hottest March on record and temperatures over 40 degrees Celsius (and in some places approaching 50 degrees) are making it almost impossible for 1.4 billion people to work. It's damaging crops and it's just what climate scientists have been warning about. Roland Pease talks to Vimal Mishra of the Indian Institute of Technology in Gandhinagar about the impact and causes of the unprecedented heatwave. What could be behind the incidence of hepatitis in young children around the world in recent months? Ordinarily, liver disease in childhood is extremely rare. Could a virus normally associated with colds be responsible or is the Covid virus involved? Roland Pease talks to virologist William Irving of Nottingham University. Also in the programme: how climate change is increasing the likelihood of animal viruses jumping the species barrier to humans with global change modeller Colin Carlson of Georgetown University, and myths about the personalities of dog breeds are exploded with new research by Elinor Karlsson of the University of Massachusetts Medical School. (Photo: Woman cooling herself in India heatwave Credit: Debajyoti Chakraborty/NurPhoto via Getty Images) Presenter: Roland Pease Producer: Andrew Luck-Baker

The Science Hour
Climate techno-fix would worsen global malaria burden

The Science Hour

Play Episode Listen Later Apr 24, 2022 67:40 Very Popular


As a series of UN climate reports have warned recently, drastic reductions in greenhouse gas emissions – a halving over the next decade – are needed if we are to keep global warming down to manageable levels. No sign of that happening. An emergency measure to buy time that's sometimes discussed is solar geoengineering – creating an atmospheric sunscreen that reduces incoming solar heat. Sulphate compounds in volcanic gases or in industrial fumes attract water vapour to make a fine haze and have that effect. The difference would be starting a deliberate programme of injecting sulphate particles into the stratosphere. There are a host of arguments against it, including a revulsion against adding another pollutant to the atmosphere to offset the one, carbon dioxide, that's giving us problems in the first place. Another objection, outlined this week, is that it could set back the global fight against malaria - a major killer in its own right. University of Cape Town ecologist Chris Trisos tells Roland Pease what his team's modelling study revealed. Yale University neurologist Kevin Sheth talks to us about a revolution in medical scanning – small-scale MRI machines that can be wheeled to the patient's bedside. According to palaeontologist Maria McNamara, an amazingly preserved pterosaur fossil from Brazil proves that some of these flying reptiles did have feathers similar to those of birds (and some dinosaurs), and that the feathers were of different colours, possibly for mating display. Primatologist Adrian Barnett has discovered that spider monkeys in one part of the Brazilian Amazon seek out fruit, full of live maggots to eat. Why? The ancient Maya flourished in modern day Mexico and Central America for millennia. They built incredible cities and they had sophisticated knowledge of astronomy, architecture and the natural world. But although Maya culture continues to exist today, around 900 AD, many of their great settlements collapsed, and today they lie in ruins. CrowdScience listener Michael wants to know - how did the Maya sustain their populations successfully for so long? And what happened 1000 years ago that led them to abandon their cities? To find out, Melanie Brown travels to the forests of Western Belize. She visits the archaeological site of Xunantunich to learn about what life would have been like for the Maya living in what was once a prosperous city. She hears about the importance of water to the Maya way of life in this region, and their ingenious methods for capturing and storing rainfall. She meets archaeologists using lasers and drones to map Maya settlements that have lain hidden by jungle for centuries. And she discovers what material from the bottom of lakes can tell us about how the Maya faced a changing climate, which may have had huge consequences for their society. (Photo: Illustration of a mosquito biting Credit: SCIEPRO/Science Photo Library/Getty Images) Presenters: Roland Pease and Melanie Brown Producers: Andrew Luck-Baker and Anand Jagatia

Science in Action
Climate techno-fix would worsen global malaria burden

Science in Action

Play Episode Listen Later Apr 21, 2022 33:07


As a series of UN climate reports have warned recently, drastic reductions in greenhouse gas emissions – a halving over the next decade – are needed if we are to keep global warming down to manageable levels. No sign of that happening. An emergency measure to buy time that's sometimes discussed is solar geoengineering – creating an atmospheric sunscreen that reduces incoming solar heat. Sulphate compounds in volcanic gases or in industrial fumes attract water vapour to make a fine haze and have that effect. The difference would be starting a deliberate programme of injecting sulphate particles into the stratosphere. There are a host of arguments against it, including a revulsion against adding another pollutant to the atmosphere to offset the one, carbon dioxide, that's giving us problems in the first place. Another objection, outlined this week, is that it could set back the global fight against malaria - a major killer in its own right. University of Cape Town ecologist Chris Trisos tells Roland Pease what his team's modelling study revealed. Yale University neurologist Kevin Sheck talks to us about a revolution in medical scanning – small-scale MRI machines that can be wheeled to the patient's bedside. According to palaeontologist Maria McNamara, an amazingly preserved pterosaur fossil from Brazil proves that some of these flying reptiles did have feathers similar to those of birds (and some dinosaurs), and that the feathers were of different colours, possibly for mating display. Primatologist Adrian Barnett has discovered that spider monkeys in one part of the Brazilian Amazon seek out fruit, full of live maggots to eat. Why? Presenter: Roland Pease Producer: Andrew Luck-Baker (Photo: Illustration of a mosquito biting Credit: SCIEPRO/Science Photo Library/Getty Images)