Podcasts about ons

Nieuwe attractie verpest de Efteling-wedstrijd voor PSV, de 25 zoons van Van Persie winnen met moeite van de kleinste broer en we hebben te maken met een Spaanse conmoción in Amsterdam. Verder deed de Jizz Hornkamp derby zijn naam eer aan voor Heracles en brengt tovenaar Ihattaren Fortuna Sittard naar de magische grens. Het is maandagavond, de mammoet is niet meer uitgestorven, op naar een nieuwe aflevering van De Derde Helft met deze week Michel Doodemans aan tafel. ✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

"Our goal of precision oncology has been to shift to tailored therapies that can help to improve treatment efficacy and ultimately improve patient outcomes. Resistance biomarker testing can help the care team to detect these genomic changes that the tumor may have acquired during therapy that makes the cells resistant to therapy. This information can be extremely helpful when we're talking about making choices about second-line or subsequent-line therapy," ONS member Danielle Fournier, DNP, APRN, AGPCNP-BC, AOCNP®, advanced practice RN at the University of Texas MD Anderson Cancer Center in Houston, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about drug resistance biomarker testing. This podcast episode is sponsored by AstraZeneca. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Episode Notes  This episode is not eligible for NCPD credit.  ONS Podcast™ episodes: Episode 389: Biomarker Testing for Non-Small Cell Lung Cancer Episode 373: Biomarker Testing in Prostate Cancer Episode 169: How Biomarker Testing Drives the Use of Targeted Therapies ONS Voice articles: Help Your Patients Understand Biomarker Resistance Testing Key Patient Education Points for Biomarker Resistance Testing Quick Quiz: How Much Do You Know About Drug Resistance in Cancer? Quick Quiz: How Much Do You Know About Somatic Biomarker Resistance Testing? When Targeted Therapy Stops Working, What's Next? Discover How Biomarker Resistance Testing Opens New Doors ONS Biomarker Database Clinical Journal of Oncology Nursing article: Tumor-Agnostic Therapies Reshaping Cancer Care ONS book: Understanding Genomic and Hereditary Cancer Risk: A Handbook for Oncology Nurses ONS course: Genomic Foundations for Precision Oncology ONS Genomics and Precision Oncology Learning Library American Cancer Society Cancer Action Network: Access to Biomarker Testing page White paper: The Landscape of Biomarker Testing Coverage in the United States Find out which states are currently discussing biomarker testing bills and how you can advocate for them through ONS. To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "We know that biomarkers are playing an ever more important role in cancer care, and really, their use can range anywhere from helping us to confirm a given diagnosis, understand a patient's cancer susceptibility or risk, evaluate prognosis, as well as personalize treatment recommendations. … But in some cases, though, biomarkers can also help us to avoid therapies that are not likely to work. We also call these drug resistance biomarkers. These are those biomarkers that signify that a tumor is unlikely to respond to a given therapy." TS 1:50 "Resistance to cancer therapies is one of the most common issues that arises during cancer treatment. Because the populations of cancer cells within a tumor can be very diverse, when a given drug kills the cells that are sensitive to that therapy, it can also eventually leave behind resistant tumor cells, which can grow and multiply over time. So this can ultimately lead to a point where the treatment that was initially effective is no longer able to control the disease." TS 4:33 "While costs have come down, there can still be a cost associated with biomarker testing, and in some cases, this can be considered a barrier to care. What patients pay out of pocket can vary widely depending on their insurance coverage. So we have some data that was published from the American Cancer Society Cancer Action Network, and this was published a few years ago in 2023, which showed the average allowed unit cost to insurers per biomarker test ranged anywhere from about $79 for patients who were on Medicaid to about $224 for large-group, self-insured patients." TS 10:03 "There's research underway that's looking not only at genomic changes—so DNA changes that impact drug resistance—but how other substances such as RNA and proteins within the cell can also contribute to drug resistance. And this kind of falls into not just genomics but multiomics field. I have no doubt whatsoever that the use of artificial intelligence and machine learning is likely going to play a large role in drug resistance research. And really, these tools can help researchers to analyze complex data sets, identify novel resistance biomarkers, predict resistance patterns, as well as help to develop treatments that may overcome some of those resistance mechanisms." TS 17:00

Voor karateka Samantha van Lokven was 2025 een geweldig jaar. Alles wat ze aanraakte veranderde in goud, met als hoogtepunt twee Europese en een wereldtitel in een week tijd. Inmiddels is het 2026 en staat ze vlak voor de uitdaging om haar wereldtitel te gaan verdedigen. Ons voormalig Talentboek Talent van de Maand schoof bij ons aan in de studio om alles te vertellen over haar sport en weg richting hopelijk titelprolongatie eind maart. Meer weten en Samantha ondersteunen? Kijk dan hier: https://yvgtf.nl/talentboek/wk-malta-2026 Presentatie: Robert Denneman

Episode Overview: In this practical episode of the Long Term Care RD podcast, Michelle breaks down a real-world sample nutrition care plan for a resident with a stage 3 pressure injury. Drawing from over a decade in SNFs, we cover the Nutrition Care Process step-by-step, MDS requirements, and tips to make your documentation survey-ready while supporting better healing for your older adults. Whether you're juggling MDS deadlines or looking for quick interventions to boost protein intake, this episode is designed to save you time and build your confidence in geriatric wound care.Key Takeaways:How to craft a specific Nutrition Diagnosis (PES statement) for increased protein/energy needs tied to wounds.Setting measurable goals for healing, weight maintenance, and intake — with geriatric nuances like potential weight gain.Multi-layered interventions: From fortified foods and ONS to interdisciplinary referrals (e.g., OT for positioning).Monitoring strategies to stay proactive on quality measures and prevent burnout.A ready-to-adapt sample chart note in SOAP format for your own residents.Resources Mentioned:Downloadable Your FREE RD Starter Kit!: Grab the full example we discussed, including the resident briefing, NCP details, MDS section, and chart note. Available as a free teaser on https://fantastic-frost-95925.myflodesk.com/ggnskwevs8 — perfect for quick reference in your facility.Full Wound Healing Toolkit in Clinical Nutrition Central: For even more depth, join the membership to access downloadable templates for all wound stages, PES statement guides, charting libraries, monthly updates on CMS regs/PDPM, and a community forum for LTC RDs. Designed by someone who's been in your shoes, for RDs working with older adults. Check it out at https://clinicalnutritioncentral.comRelated Blog Post: "Wound Care Dietitian - Step by Step Practical Advice" — Read it free at https://longtermcarerd.com/wound-care-the-dietitians-role2/.Thanks for Listening! If this episode helped you feel a bit more equipped for those wound care challenges, share it with a fellow RD and subscribe for more practical geriatric nutrition tips. Got questions or episode ideas? Drop a comment on the blog or join us in Clinical Nutrition Central. You've got this — let's keep supporting our seniors together.Hosted by Michelle Saari, MS, RD LongTermCareRD.com | ClinicalNutritionCentral.com

PSV slaat zich met vrijbriefje langs AZ en Wouter Goes, Feyenoord blaast motor Sterling bijna op voor een punt tegen NAC en Ajax verliest van zelf gecreëerde angstgegner. Verder speelt een dronken NEC Volendam dronken, kan FC Twente Bernabeu al ruiken en kan Telstar nog een jaar Eredivisie bijna aanraken. Het is maandagavond, Sanne van Dongen maakt vanavond haar eerste minuten in De Derde Helft, dus op naar een nieuwe aflevering. ✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

Ik heb mijn gast in deze aflevering eerst op televisie gezien, tijdens verkiezingsprogramma's komt hij altijd uitleggen waarom mensen op extreem-rechts stemmen. Ik had soms het gevoel dat hij de enige man in ons land was die daar iets zinnigs over te zeggen heeft. Hij heeft boeken geschreven, ondermeer Niet alles maar veel begint bij luisteren – Een verslag uit de Denderstreek, en En wat nu? - de coup van Trump en de superrijken.Dominique Willaert (1968) werd geboren in een arbeidersgezin in West-Vlaanderen. Hij woont nu in Lievegem in Oost-Vlaanderen, tegenover een grote fabriek. Ik werd meteen begroet door zijn twee honden Tosca en Muna (moena), die slecht opgevoed zijn, zegt hij zelf. We gingen zitten in zijn werkkamer, twee muren vol boekenkasten. Ons gesprek gaat over zijn arbeidersachtergrond, over de gevaren van de stad en de angst van zijn ouders, over klassepijn, over zijn Turkse buurman, over het belang van goede leraren. Hij zegt dat boeken zijn leven gered hebben.Alle boeken en auteurs uit deze aflevering vind je⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠in de shownotes op wimoosterlinck.be⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Wil je de nieuwsbrief in je mailbox? ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠wimoosterlinck.substack.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Wil je de podcast steunen? Bestel je boeken dan steeds via⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠de ⁠⁠link op wimoosterlinck.be⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠!⁠⁠ Merci.De drie boeken van Dominique Willaert zijn:1. Olga Tokarczuk – Empusion2. Barbara Kingsolver – Demon Copperhead3. Louis Paul Boon – De KapellekensbaanLuister ook naar de drie boeken van: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Stefan Hertmans⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Eva Mouton⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nicci French⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josse De Pauw⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Ish Ait Hamou⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Murielle Scherre⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠,  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Michèle Cuvelier⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠Françoise Chombar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠en ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vele anderen⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Wil je het boek '103 boeken die je gelezen moet hebben' bestellen - het boek van de podcast? Dat kan op ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠wimoosterlinck.be.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Ik schrijf er met plezier iets in voor jou of voor de persoon aan wie je het boek cadeau wil doen.

Ons moet vestings (skanse) neer werp...

Uur 1 1. Little boy you've had a busy day – Bing Crosby 2. Ik zou wel eens willen weten – Martine Bijl 3. Je t'aimais, je t'aime, je t'aimerai – Hiba Tawaji 4. Change the world – Eric Clapton 5. You can love yourself – Keb'Mo' 6. Smeòrach – Sian 7. I never dreamed you'd leave in summer – Stevie Wonder 8. In dit hoes – Arno Veeman 9. My love, my life – ABBA 10. S.O.S. – Chris de Burgh 11. Last night I heard America – Martyn Joseph 12. Open einde – Ellen ten Damme 13. Sommarkort – Cornelis Vreeswijk 14. Married life – Michael Giacchino   Uur 2 1. Hallelujah – Jeff Buckley 2. To the ends of the world – Nat King Cole 3. Entrelazados – Doble Valentina  4. Ons mors on tyd – Stef Bos 5. Stay with me till dawn – Judy Tzuke 6. Two shots of happy, one shot of sad – Nancy Sinatra 7. J'aime Paris au mois de Mai – Zaz & Charles Aznavour 8. Lekker nummer - Spijkers 9. Serenade – Della Reese 10. Clair de lune/Photograph – Cody Fry 11. Weg naar huis – Beatrice van der Poel 12. Laugh and be happy – Randy Newman 13. 58th Street – Bobby Bryant Sextet

Send a textNehemia 8:10 Hy het ook vir hulle gesê: “Gaan eet 'n lekker maaltyd en drink soet drankies. Deel ook van die kos met mense wat niks voorberei het nie. Hierdie is 'n dag wat aan ons God toegewy is. Moenie terneergedruk wees nie, want die blydskap wat die Here gee, sal julle krag wees! (NLV) Ons lewens bestaan uit twee afsonderlike dele – die dinge wat uiterlik sigbaar is; die dinge wat ons sien, doen en sê, en die dinge wat ons aan die binnekant dink en voel. Hulle is uiteraard aanmekaar verbind, maar daardie diep innerlike lewe bly vir die res van die wêreld verborge.Elke nou en dan breek ons innerlike lewe deur. Ons woede breek uit in driftige woorde; ons liefde in teerheid.Oor die algemeen probeer ons ons negatiewe emosies wegsteek – ons trots, ons wrokke, ons vrese, ons bekommernisse, ons gevoel van ontoereikendheid, ensovoorts. Hierdie emosies spoel soos ‘n wasmasjien om en om in ons harte, dit verdraai ons perspektief; dit vernietig ons verhoudings. En al probeer ons hulle onderdruk, vreet hulle soos kanker aan ons. Maar, moenie jouself bluf nie, al probeer jy dit wegsteek, weet ander mense dat iets verkeerd is.Hoe oorwin jy jou negatiewe emosies? Hoe keer jy dat hulle nie soos 'n oop sweer jou lewe met hulle gif besmet nie? Jy het bonatuurlike krag nodig om hulle baas te raak, om hulle te oorwin en om hulle finaal uit te wis.Nehemia 8:10 Nehemia het gesê: “Gaan geniet keurige kos en soet drankies, en stuur daarvan aan diegene wat niks voorberei het nie. Hierdie dag is heilig aan ons Here. Moenie treur nie, want die vreugde van die HERE is julle krag.” (NIV)Die mense het gehuil toe God se wet hardop vir hulle voorgelees is en hulle het besef hoe skuldig hulle was. Nehemia het hulle egter vermaan om nie bedroef te wees nie, omdat God behae daarin skep wanneer sy mense vrolik is. Sy genade bring krag wat die negatiewe strominge in ons harte heeltemal oorweldig, heeltemal oorwin, heeltemal uitwis.Hierdie dag is heilig aan ons Here. Moenie treur nie, want die vreugde van die HERE is julle krag.Dis God se Woord. Vars … vir jou … vandag.Support the showEnjoying The Content?For the price of a cup of coffee each month, you can enable Christianityworks to reach 10,000+ people with a message about the love of Jesus!DONATE R50 MONTHLY

Send a textJesaja 6: 8 Toe het ek die Here hoor vra: “Wie kan Ek stuur? Wie sal ons boodskapper wees?” Ek het geantwoord: “Hier is ek! Stuur my!” As jy oortuig is dat God jou roep en dat Hy wil hê dat jy jou gawes tot sy eer moet gebruik – dan is jy werklik geseënd. Maar hier is die probleem: daar is altyd 'n prys daaraan verbonde. En dis dikwels dáárdie prys wat ‘n mens keer om die stap te neem in die rigting wat ware, blywende vervulling bring.David Livingstone het geglo dat God hom as 'n sendeling, en ontdekkingsreisiger na donker Afrika geroep het. Sy primêre doel was om die Evangelie aan onbereikte mense te bring. Maar toe hy die brutaliteit van die slawehandel eerstehands aanskou het, het hy sy ontdekkingsreise ook gesien as ‘n manier om Afrika oop te maak vir die Boodskap van Christus en vir wettige handel, in die hoop om slawerny te beëindig. Vir Livingstone het sy reise nooit oor roem gegaan nie; dit was uit gehoorsaamheid aan God se roeping om te dien, te genees en te bevry.Wanneer God jou roep, kan dit 'n moeilike pad wees. Hy het Jesaja geroep as 'n Profeet vir Israel, wat ver van hul God afgedwaal het. Die man moes God se oordeel oor hulle uitspreek. Hoe gewild dink jy het dit hom gemaak? Ons lees dat Jesaja toe hy in die tempel gebid het …Jesaja 6:8 ...het ek die Here hoor vra: “Wie kan Ek stuur? Wie sal ons boodskapper wees?” Ek het geantwoord: “Hier is ek! Stuur my!”Watter roeping het God op jou lewe geplaas? Het die prys wat dit van jou vra, jou dalk gekeer om te sê: Hier is ek. Stuur my?Livingstone het, na alles wat hy deurgemaak het, gesê: As 'n opdrag deur 'n aardse koning as 'n eer beskou word, hoe kan 'n opdrag deur 'n hemelse koning as 'n opoffering beskou word?”Toe sê ek: “Hier is ek. Stuur my!”Dis God se Woord. Vars … vir jou … vandag.Support the showEnjoying The Content?For the price of a cup of coffee each month, you can enable Christianityworks to reach 10,000+ people with a message about the love of Jesus!DONATE R50 MONTHLY

Soms voel die voorbeeld en woorde van Jesus so verkeerd-om vreemd. Ons dink ons verstaan: hoe die lewe werk; wie suksesvol is; wie geseënd is; wie naby aan God is; hoe die mooi en goeie lewe lyk…En dan begin Jesus Sy riglyne vir die koninkrykslewe met woorde wat alles omkeer: “Geseënd is die wat arm van gees is, want aan hulle behoort die koninkryk van die hemele.” Skielik besef ons: Die Koninkryk van God werk anders, en dit is vir ons gekondisioneerde manier van dink, kyk en leef moeilik om hierdie verkeerd-om lewe te verstaan, te vertrou en te leef. Kom kry Sondag saam met ons helderheid oor die onbegryplike. … Luister hier na die klankopname of op die potgooi-platform van jou keuse. . . Of kyk hier saam:

"The disease is increasingly managed as a chronic condition rather than a diagnosis with an immediate terminal outcome. Particularly, with earlier and more effective and sustained treatment options, we can make this disease a very chronic, long-term, livable condition. I want to make sure that patients are aware that this is not a death sentence. This is something that patients can live with for the long term," Ann McNeill, RN, MSN, APN, nurse practitioner at the John Theurer Cancer Center at Jersey Shore University Medical Center in Neptune, NJ, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about long-term multiple myeloma considerations for oncology nurses. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by March 6, 2027. Ann McNeill is on the speakers' bureau for Pfizer. This financial relationship has been mitigated. All other planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to management of long-term side effects related to multiple myeloma and treatment. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 401: Multiple Myeloma Treatment Considerations for Oncology Nurses Episode 398: An Overview of Multiple Myeloma for Oncology Nurses Episode 339: A Lesson on Labs: How to Monitor and Educate Patients With Cancer Episode 201: Which Survivorship Care Model Is Right for Your Patient? ONS Voice articles: Effective Care Transitions Are Essential for New Multiple Myeloma Treatments Infection Prevention for Oncology Nurses Multiple Myeloma Prevention, Screening, Treatment, and Survivorship Recommendations Nurse-Led Survivorship Programs Sexual Considerations for Patients With Cancer Oncology Nursing Forum articles:  A Qualitative Study of the Experiences of Living With Multiple Myeloma Changes in Health-Related Quality of Life During Multiple Myeloma Treatment: A Qualitative Interview Study ONS book: Multiple Myeloma: A Textbook for Nurses (third edition) ONS Huddle Cards: Pain Management Sexuality Survivorship Care Plan ONS Learning Libraries: Hematology, Cellular Therapy, and Stem Cell Transplantation Survivorship ONS Symptom Intervention resources: Chronic Pain Fatigue Peripheral Neuropathy American Cancer Society: Living as a Multiple Myeloma Survivor Blood Cancer United: Resources for Healthcare Professionals International Myeloma Foundation: Resources and Support for the Myeloma Community Multiple Myeloma Research Foundation: Empower Patients and the Community To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "We do consider myeloma an incurable hematologic malignancy, even though we have had improvements in survival. But just like for any malignancy, our goal is to maximize survival. We want to eliminate as many myeloma cells as we possibly can. And subsequently, we want to improve the quality of life for these patients in the long term. So those are basically our treatment goals. That's what we think of when we're treating patients all throughout their treatment journey." TS 1:39 "It is very typical for patients along their journey to have received several lines of therapy. I think it's important to realize that the cells acquire new mutations, making them more resistant to these further subsequent lines of therapy. We see quicker, more aggressive relapses in those patients with multiple prior lines of therapy. We can see an increase in the CRAB symptoms, which are the calcium elevations, the renal dysfunction, profound anemia, and even bone disease. We can see a rapid rise in the monoclonal protein in the labs or even a very rapid rise in the involved light chain in that serum free light chain assay, so it's important to monitor these labs." TS 9:14 "All oncology nurses are focusing on these survivorship plans now. And I think that's a great thing when you think about a diagnosis of cancer and a survivorship plan, because it means these patients are living a longer time. We still look at long-term health maintenance guidelines depending on the patient's sex and their age. ... I think preventing infection is always going to be something absolutely on the forefront in our survivorship plan with myeloma. I mean, myeloma is an immune system malignancy. The treatments that we have given patients can sometimes, especially in later life therapies, further compromise the immune system. So, we're always looking to prevent serious infection." TS 12:46 "Patients get treatment, especially induction therapy. They may or may not get transplant. They may have been on a very minor maintenance schedule, depending on their age. And they feel really well. And then they decide not to return for their follow-up because they feel so good. I think nurses are critical in the communication aspect of the patient-provider aspect. So, nurses are really the key means of communication. The providers are absolutely important—the physicians, the nurse practitioners and every other member of the team—but I think the nurses have a really special rapport with patients. They're usually the ones providing the education on the treatment regimens. They're managing the toxicity profiles. They're doing all the coordination of care between visits. They are really going to be the ones telling the patient, 'Hey, you're going to feel good and that's a wonderful thing, but you still need to come once a month or once every six weeks or once every two months for your labs.'" TS 15:17  "It has been amazing. The science, the research, the treatments, the approvals from the U.S. Food and Drug Administration. Survivorship has improved dramatically. Let's take the first few years of the new century, right? The five-year survival rate was about 38%. If you then jump to 2015–2019, which is still seven plus years ago, it has doubled. So, we're talking about anywhere from 60%–80% over a five-year survival. So that's an amazing improvement in their five-year survival rate for myeloma." TS 23:28 "Survivorship in myeloma begins at diagnosis, not just after treatment. And I think that because it is managed as a chronic, often relapsing disease, it does require lifelong evolving care. Patients should realize that they will know us for the rest of their lives. We will know everything about you. I always tell them, 'I will know everything about your hobbies, your children, your grandchildren, what you love to do on the weekends.' It's very important that that point is made right at diagnosis, not just after so many lines of treatment. It's very important that we are going to follow these patients throughout their journey." TS 28:18

De Onzichtbare Strijd in Ons, Genezing, Allergieën en de Kracht van HerstelIn dit eerlijke gesprek duiken we in de rommelige, emotionele waarheid van onze lichamen die stille oorlogen voeren, allergieën, irritaties en die terugkerende problemen die we maar niet lijken te kunnen oplossen. Het gaat niet alleen om fysiek ongemak; het is een spiegel van hoe we onszelf behandelen, hoe we reageren op verandering en hoe het leven soms gewoon obstakels blijft opwerpen.In deze aflevering:- De verrassende impact van Westerse hygiëne op ons immuunsysteem- Hoe allergieën zich ontwikkelen en waarom ze in de loop van de tijd erger worden- De frustratie van terugkerende problemen, en de noodzaak om ze te confronteren- Het belang van respect voor de signalen van ons lichaam en natuurlijke herstelprocessen- De metafoor van schoonmaken en vernieuwing: soms moet je loslaten voordat het nieuwe kan komen- Waarom het aanpakken van één probleem vaak leidt tot het ontdekken van een ander, zoals het pellen van een ui- Persoonlijke verhalen van fysieke en emotionele worstelingen die ons allemaal verbinden- De emotionele tol van het gevoel de controle kwijt te zijn en leren over te gevenTijdstempels: 00:00 - Het vrijdaggevoel en de rommel van stof in het leven 00:09 - De onzichtbare tol van allergieën en Westerse hygiëne 00:20 - Hoe ons immuunsysteem overweldigd kan raken 00:40 - Persoonlijke gezondheidsstrijd en schijnbaar eindeloze problemen 00:54 - Waarom allergieën en reacties in de loop van de tijd verergeren 01:20 - De cyclus van het onder ogen zien van terugkerende problemen 01:25 - De frustratie van problemen die steeds terugkomen 01:52 - Hoe onze omgeving onze gezondheid beïnvloedt 02:02 - De impact van overmatige hygiëne en steriele omgevingen 02:11 - Het belang van vertragen en herstellen 02:20 - Verbinding maken met de chaos en chaos in onszelf 02:25 - Vragen naar plannen en de wens voor verandering 02:30 - Nieuwe avonturen plannen en de onvoorspelbaarheid van het leven omarmen 02:36 - De vreugde van vieren en verbinding maken 02:39 - De chaos van eindeloze takenlijsten en problemen 03:02 - Het mentale obstakel van overweldigd voelen overwinnen 03:20 - De meedogenloze cyclus van problemen en oplossingen 03:29 - De noodzaak van geduld en begrip in genezing 03:48 - Het patroon herkennen: elke oplossing onthult een nieuwe uitdagingDeze aflevering is voor iedereen die moe is van het vechten tegen dezelfde gevechten, het is tijd om naar de fluisteringen van je lichaam te luisteren en misschien, heel misschien, de moed te vinden om opnieuw te beginnen.SPONSORSIBV ConsultancyAndreArt.nlJPSystemsENGLISH CHANNELSVideo: YouTube.com/@JackJozef Podcast: Spotify, TikTok, Instagram & LinkedInWebsite: www.JACKJOZEF.comContact: info@PodcastGemist.nlNEDERLANDSE KANALENVideo: YouTube.com/@podcastgemist Podcast: Spotify, TikTok, Instagram & LinkedInWebsite: www.JACKJOZEF.nl

Die akteur en komediant, Soli Philander, sterf. Die gedragskomitee se skudigbevinding van drie senior politici in die Wes-Kaap vang die wetgewer onkant. Ons praat oor die toekoms van die progressiewe of linkse politiek in Suid-Afrika.

This week Michela and the FT's US banking editor, Joshua Franklin, interview the co-creators of the hit television show, Industry. In its fourth season, the show follows the lives of ambitious young people making their way in London's financial centre. The season finale aired earlier this week, and in this episode, Michela and Joshua discuss with the creators, Mickey Down and Konrad Kay, the overlap between their show's storylines and real world finance. The FT does not use generative AI to voice its podcasts.- - - - - - - - - - - - - - - - - - - - - - - - - - For further reading: The ONS vs Industry How I won a starring role — OK, bit part — in HBO's ‘Industry'Inside Wirecard For further listening:How Wirecard's Jan Marsalek went from fraudster to spy HBO's 'Industry', and Esther Perel - - - - - - - - - - - - - - - - - - - - - - - - - - Michela Tindera is on X (@mtindera07) and Bluesky (@mtindera.ft.com), or follow her on LinkedIn for updates about the show and more.Read a transcript of this episode on FT.com Hosted on Acast. See acast.com/privacy for more information.

Ons bid maklik, maar is ons gewillig om te wag ook? Om te wag is deel van God se vormingsproses.

Ons gesels oor die belangrike verskil tussen angstigheid en paniek, en help jou verstaan wanneer Irma Rescue Panic die regte keuse vir jou kan wees. Ons bespreek praktiese voorbeelde en gee duidelikheid oor hoe om emosionele uitdagings beter te hanteer met die regte ondersteuning. Alles is gereël aan my kant. Ek sal organiseer om met jou via Cleanfeed te gesels; anders kan jy inskakel via WhatsApp by +27 72 984 7566. Die Irma Rescue-reeks, insluitend Irma Rescue Panic, is beskikbaar by jou naaste apteek sowel as op die Clicks-rakke. Vir navrae oor die Irma Rescue-reeks, asook emosionele en algemene gesondheidsvrae, kontak info@sanatural.co.za

Ons redding rus nie op ons prestasie nie.

Luister hier na die klankopname of op die potgooi-platform van jou keuse of lees die blog-inskrywing hier onder. . . Na-leef gedagte — 'n Sodat/omdat benadering? Nou die aand sit ek langs Pierre om die ou aan te moedig om sy Gr 7 Ekonomie-opsommings te maak. Êrens in een van die gedagtes oor geld en ekonomie is daar 'n sinnetjie wat iets klink soos “mense werk sódat hulle meer geld kan kry, sódat hulle meer goedere kan koop”. Die presiese bewoording ontgaan my nou, maar wat my opgeval het was die woord “sodat” en die rilling deur my siel oor hierdie wêreld waaraan hy en ons blootgestel word. Hierdie “sodat-wêreld”. 'n Wêreld waarin jy moet perform so hard en so goed as wat jy kan, selfs bo wat gesond is, sodat jy kan kry, kan vermag, gereken kan word. Dit is 'n uitputtende wêreld. 'n Wêreld wat leeg tap. Wat opgebruik. Wat 'n valse selfvertroue kweek. Wat jou verskraal tot 'n objek, 'n rat in 'n masjien. Sodat jy kan kry wat jou kwansuis sal gelukkig maak. Heinrich se Sondag-boodskap uit die saligspreuk (Matt 5:6) oor “Gelukkig is die wat honger en dors na geregtigheid want hulle sal versadig word” en sy keuse om die geregtigheid te verstaan as die ou gedagte dat ons in die regte – kindskap – verhouding met God kan leef, het my laat dink aan die onverwagse (lees versadigende) omdat-lewe wat Christus vir ons kom gee. Hierdie omdat-aard van ons geloof, verlossing en kindskap het my herinner aan jare gelede: Ongeveer 'n jaar na my ma en my stiefpa getroud is het ek 21 geword. 'n Interessante fase in my lewe, waar ek so onafhanklik as moontlik wou word, om 'n nuwe kindskap aan te leer. Met my mondigwording roep Oom Steve (my aangetroude pa) my eenkant en gee vir my 'n geskenk in 'n klein boksie. Opgewonde, half onbeholpe met die intieme oomblik tussen ons, maak ek dit oop om die kosbare geskenk van 'n Kruger-rand te ontvang. Hy verduidelik die simboliese waarde van die geskenk met “Ek het vir elkeen van my kinders 'n Kruger-rand gegee toe hul 21 geword het en ek wil graag vir jou ook een gee want ek wil hê jy moet weet, daar is vir my geen onderskeid tussen jou en my kinders nie.” Wat 'n kosbare geskenk!!! Omdat ek aan my ma behoort, behoort ek ook aan hom en hierdie behoort is nie iets wat ek moes doen, moes verdien of moes bereik nie. Oom Steve het my ook mooi laat verstaan dat hy nie my lojaliteit probeer koop nie – maar vir my 'n omhelsing, 'n sekerheid, 'n behoort wou gee. Die Kruger-rand-geskenk was nie die eintlike ding nie, dit was bloot die simbool van iets ver bo die waarde van wat die goud-prys ookal was. Soos met die Kruger-rand moes ek hierdie kindskap, en al die wonders daarvan, eenvoudig net ontvang. Dit het ons verhouding verander van 'n sodat na 'n omdat. Hierdie omdat het my vry gemaak, gevorm, veilig laat voel, waagmoed gegee, tuis laat kom, laat wees…omdat hy my sy kind gemaak het. Sodat-verhoudings is kunsmatig, het bymotiewe, is op jouself gefokus. Omdat-verhoudings gee sekerheid want die grond van hierdie verhouding lê nie in jou nie – maar in die onvoorwaardelike verbintenis van iemand aan jou. Sodat-verhoudings is 'n transaksie wat eis. Omdat-verhoudings is 'n verbintenis wat gee. Sodat-kindskap sê “As jy…dan kan jy…” Omdat-kindskap sê “Aangesien jy is…wees nou…” Ons hele wêreld is gebou en gerat op hierdie sodat-benadering. Dit maak dit moeilik om die omdat-lewe wat Christus vir ons kom gee te aanvaar, te onthou en na te leef. Pierre is in 'n belangrike oorgangsjaar van sy lewe. Meer as enige iets anders hoop ek hy kan hierdie omdat-lewe ontdek: Hê lief omdat, nie sodat nie. Werk hard omdat, nie sodat nie. Glo in en volg Jesus omdat, nie sodat nie. Hê respek vir alle mense en die ganse skepping omdat, nie sodat nie. Omdat vul jou met verwondering en dankbaarheid. Dit maak jou bewus van heiligheid. Sodat verskraal die lewe tot jou self en die lewe word 'n masjien, projek, tog…waardeur jy een of ander mitiese gelukkigheid of seën gaan bereik en intussen mis jy wat reeds is en altyd sal wees. Die saligspreuke begin elkeen met “Geseënd is…” nié met “Geseënd sal jy wees as jy…” In Lukas 15 kon albei die verlore seuns, die een wat tuisgebly het en die een wat op ‘n lang verdwaalreis gegaan het, eers regtig tuiskom omdat hulle ontdek het wie en hoe hulle pa is en dat hulle aan hom behoort. Na-leef teks “Kind, jy is altyd by my, en alles wat ek het, is ook joune.” Lukas 15:31 Na-leef vraag Het jy 'n sodat- of 'n omdat-verhouding met God? Watter verhoudings in jou lewe het nodig om te skuif van 'n sodat-benadering na 'n omdat-benadering? En hoe gaan jy die verskil leef? Waarom werk jy…Sodat of Omdat? Hoe sou die verskillende benaderings vir jou lyk?

PSV houdt geen rekening met Fabers sabbatical, FC Twente verlengt de reeks terwijl Feyenoord alleen de blessurelijst verlengt en PEC is iets meer Barcelona dan Ajax. Verder stelen de Eagles dit keer geen flessen drank, maar punten, en pakt NAC inderdaad zes punten na carnaval, maar Telstar zes punten in één wedstrijd. Het is maandagavond, op naar een nieuwe aflevering van De Derde Helft.✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

Twintig amptenare van die Departement van Binnelandse Sake is ontslaan, en 16 geskors. Ons praat met 'n militêre kenner en 'n ekonoom oor die konflik in die Midde-Ooste. Inwoners van Graaff-Reinet betoog teen die naamsverandering na die Robert Sobukwe-dorp.

Wat betekent het om ouder te worden in een digitale wereld? In gesprek met denkers en kunstenaars naar aanleiding van PISS POOL, een baanbrekende theaterperformance die je instafeed in een ander licht zet. Met theatermakers Suzan Boogaerdt en Bianca van der Schoot, schrijvers Marian Donner en Maxime Garcia Diaz, kunstenaars Lisa Schamlé en Lydia Schouten en actrice en zangeres GerdaLentenHavertong.Ons zelfbeeld, onze aandacht en ons gevoel voor eigenwaarde worden voortdurend beïnvloed door wat we zien, delen en liken. Deze avond onderzoeken hoe de (digitale) idealen van jong, fit en strak onze ideeën over wie we zijn (ver)vormen. Hoe beïnvloedt AI onze woorden, ons gevoel van eigenwaarde en onze ervaring van tijd? En hoe blijven we met elkaar verbonden in een tijd waarin onze online representatie voortdurend aandacht opeist?We gaan hierover in gesprek naar aanleiding van de theaterperformance PISS POOL, waarin Suzan Boogaerdt en Bianca van der Schoot onderzoeken wat betekent om ouder te worden in een (beeld)cultuur die verjonging en zelfoptimalisatie centraal stelt.Programmamaker: Ianthe MosselmanZie het privacybeleid op https://art19.com/privacy en de privacyverklaring van Californië op https://art19.com/privacy#do-not-sell-my-info.

"We print education sheets that we have, and we say, 'Just ignore this part that says cancer. You're getting this med but for a different indication.' And then you have to really point out what our goals of care are. You're using the information that, as oncology nurses, we like and love, but we're having to cross it out and say, 'Just read this portion and just do this here.' And that can be challenging for the nurse and probably confusing for the patient," ONS member Brandy Thornberry, RN, OCN®, outpatient infusion and VAD supervisor at Logan Health in Kalispell, MT, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about education for patients receiving antineoplastic drugs for non-oncology indications. Taylor also spoke with ONS members Lizzy McMahon, BSN, RN, OCN®, and Jennifer Lynch, BSN, RN, TCTCN™, about general antineoplastic treatment education and tailoring education in the stem cell transplantation setting. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by February 27, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge of best practices for educating patients receiving antineoplastic therapies across oncology, non‑oncology, and stem cell transplant settings. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Episode 259: Patient Education for Health Literacy and Limited English Proficiency Episode 197: Patient Learning Needs and Educational Assessments Episode 183: How Oncology Nurses Find and Use Credible Patient Education Resources Episode 179: Learn How to Educate Patients During Immunotherapy Episode 173: Oncology Nurses' Role in Stem Cell Transplants for Pediatric Sickle Cell Disease ONS Voice articles: Online Tool Helps You Apply Health Literacy Principles to Written Patient Education Personalized Patient Education: Ensure Effective, Inclusive, and Equitable Patient Education With These Five Strategies Policies and Procedures for Written Patient-Facing Cancer Education Materials Oncology Nursing Forum article: An Integrative Review of Patient Education During Inpatient Hematopoietic Stem Cell Transplantation ONS Hematology, Cellular Therapy, and Stem Cell Transplantation Learning Library Patient Education Sheets: Cancer Care, Explained To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode McMahon: "A great question would be to ask the patient what they already know and what they're most concerned about or what their biggest questions are. This way, the nurse can tailor their education to make sure to focus on what the patient doesn't know yet and what they're most concerned about, while still touching on all the required education topics. … It's also important for nurses to continually be assessing the patient's readiness to learn throughout the education session, looking for nonverbal cues or verbal signs that the patient is overwhelmed or anxious because this is going to interfere with their ability to take in new information." TS 3:49 Thornberry: "A lot of the education sheets and the products for them explain it like, 'This is cancer,' and more of an oncology perspective, so occasionally [non-oncology patients] can show up and be confused by it. I do feel like they come a little bit less prepared than our oncology patients. Our rheumatologists and neurologists, they sure try, but they just don't have the support in that realm either. They're full of every question you can imagine. They've never been to an infusion room. They don't know what to bring. Can they drink water and have their meds beforehand? It's a full gamut of really preparing them to get these for autoimmune or rheumatology-type issues." TS 14:12 Lynch: "I really want to spend time with those patients to make sure that we are not assuming that they are coming to us with any knowledge or experience. I want them to be able to come to us with questions and trust their healthcare team and really sit down with them and say, 'Okay, you don't have cancer, but we're using the word chemotherapy where we're talking about cancer drugs.'… And we're going to probably spend more time going over some of the basics about blood stem cells, types of cells that they grow into, how your body fights infection, what they're going to be at risk for. The side effects can be pretty scary when you're talking about them, especially back to back. So making sure that we are delivering the information that doesn't put them in a panic mode… A lot of reassurance, as well, and just taking into consideration that, yes, this might have this whole other layer of anxiety to it because of the unknown." TS 32:22

UK Dentists: Collect your verifiable CPD for this episode here >>> https://courses.dentistswhoinvest.com/smart-money-members-club———————————————————————Ready to turn confusing mortgage rules into clear action steps? We sit down with specialist broker Sarah Gris to unpack how dentists can borrow more at better rates by aligning income evidence, deposits, and monthly commitments with what lenders actually reward.We start with the real levers behind the famous “multiplier.” Five times income is common, six times is realistic with the right profile, and seven times appears in niche cases at a price. Sarah explains how associates and principals should present figures: salary plus dividends or profit after corporation tax for limited companies, and net profit for sole traders. We dig into why lenders often average two years, how to time applications to showcase a strong latest year, and when projection-based pay schedules can help growing clinicians.Then we get tactical about affordability killers. A 0 percent credit card still counts, with lenders modelling around three percent of the balance as a monthly outgoing. That £10,000 you plan to clear “later” can shave roughly £80,000 off potential borrowing today. We highlight the heavy hitters—car finance, school fees, nursery costs—and translate them into mortgage impact, including how a £2,200 car payment can crowd out around a £400,000 mortgage. The message is simple: lenders view you like a business, so strip out avoidable commitments before you apply.You'll also learn how banks estimate day-to-day spend using ONS benchmarks, why flats bring service charges and ground rent into the equation, and which bank statement entries trigger underwriter questions. Sarah shares pragmatic fixes: clear or restructure revolving debt, build a stronger deposit for better rates, tidy statement references, and coordinate application timing with your best filed accounts. For dentists who like to stretch, this is the map for stretching smart.———————————————————————Disclaimer: All content on this channel is for education purposes only and does not constitute an investment recommendation or individual financial advice. For that, you should speak to a regulated, independent professional. The value of investments and the income from them can go down as well as up, so you may get back less than you invest. The views expressed on this channel may no longer be current. The information provided is not a personal recommendation for any particular investment. Tax treatment depends on individual circumstances and all tax rules may change in the future. If you are unsure about the suitability of an investment, you should speak to a regulated, independent professional. Investment figures quoted refer to simulated past performance and that past performance is not a reliable indicator of future results/performance.Send a text

Die nasionale begroting is vanmiddag in die Nasionale Vergadering gelewer deur finansminister Ericah Shafudah. Oudergewoonte, is die koste van jou twakkie en jou natmakertjie op in die komende boekjaar. Ons begin by tabak.

Trevor Kavanagh, former political editor of The Sun, joins Julia Hartley-Brewer to dissect the latest immigration and asylum figures — and the continued public anger at the gap between political spin and what people can see happening on Britain's borders.Ministers may point to a fall in work, study and family visas, a small dip in asylum claims, and fewer asylum seekers in hotels — but Julia and Trevor ask the blunt question: what does “control” look like when illegal migrants are still arriving in large numbers, with small boats surging as soon as the weather improves? Trevor argues that a government's first duty is to defend the country — and that Britain has become a destination of choice, with taxpayers left funding accommodation, food and healthcare for people who entered unlawfully.Trevor also gives his take on two other flashpoints driving distrust in politics: the murky fallout from the Mandelson arrest story, and the uncertainty around the Chagos Islands deal — including whether Britain really will hand over sovereign territory and then pay to lease back a strategic military base.Then Jamie Jenkins, former ONS statistician, explains what the data actually shows behind the headlines: year-to-date increases in Channel crossings, the scale of asylum claims, how many are granted at first decision versus on appeal, and why “fewer hotel rooms” doesn't necessarily mean fewer claimants — with many simply moved into other accommodation that is still funded by the state.Finally, Julia and Jamie turn to the other crisis hiding in plain sight: the NHS. With spending having doubled over recent years, why aren't outcomes improving? Jamie lays out the real pressure points — an ageing population (including a projected surge in over-75s), inefficiency, broken processes, and why digitisation and better productivity may matter as much as extra funding.Julia Hartley-Brewer broadcasts on Talk Monday to Thursday, 10AM to 1PM.Available on YouTube and streaming platforms, along with DAB+ radio and your smart speaker. Hosted on Acast. See acast.com/privacy for more information.

PSV-spitsen breken de ban in plaats van ledematen, Feyenoord ontwijkt wet én Telstar en Ajax-NEC eindigt in een anti-handbaluitslag. Verder was het Varnaval in Breda, slaat Fortuna de club van 27 over en gaat Faber op een zeer tijdelijke sabbatical. Het is maandagavond, op naar een nieuwe aflevering van De Derde Helft met het orakel dat je gewend bent: TIM, SNIJBOON, PEPIJN en GIJS.✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

Marie Vinck (1983) is actrice, ze maakt deel uit van het theatergezelschap FC Bergman, samen met haar man Stef Aerts. Ze maakten verschillende indrukwekkende, legendarische theatervoorstellingen, waarmee ze de wereld rondtourden. In 2023 won FC Bergman de prestigieuze Zilveren Leeuw voor Theater op de Biënnale van Venetië. Marie Vinck speelde ook in films en op tv: in Moeder waarom leven wij toen ze 10 was, in de film De kus, in Loft, De Rodenburgs, Zone Stad. Ze is de dochter van Hilde Van Mieghem.Ze woont samen met haar man en hun dochter Gloria in Antwerpen. De boekenkast hangt hoog in de living. We gingen aan tafel zitten en ze vertelt hoe voorstellingen soms ontstaan op die plek, in de living bij hen thuis. Het gaat over die ene zware voorstelling waarop ze allebei gecrasht zijn - een voorstelling gebaseerd op één van haar drie boeken. Ons gesprek gaat over de verdeling in hun boekenkast, over trauma, over deugdpronken, over hoe boeken lezen werk kan worden. Ik vraag ook of ze het leesvirus doorgegeven heeft aan haar dochter.Alle boeken en auteurs uit deze aflevering vind je⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠in de shownotes op wimoosterlinck.be⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Wil je de nieuwsbrief in je mailbox? ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠wimoosterlinck.substack.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Wil je de podcast steunen? Bestel je boeken dan steeds via⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠de ⁠⁠link op wimoosterlinck.be⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠!⁠⁠ Merci.De drie boeken van Marie Vinck zijn:Bessel van der Kolk: TraumasporenThomas Mann: De ToverbergGerard Reve: Bezorgde oudersLuister ook naar de drie boeken van: Hilde Van Mieghem, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Stefan Hertmans⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Eva Mouton⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Nicci French⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Josse De Pauw⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Ish Ait Hamou⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Murielle Scherre⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠,  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Michèle Cuvelier⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, ⁠⁠⁠⁠⁠⁠⁠Françoise Chombar⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠en ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠vele anderen⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.Wil je het boek '103 boeken die je gelezen moet hebben' bestellen - het boek van de podcast? Dat kan op ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠wimoosterlinck.be.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Ik schrijf er met plezier iets in voor jou of voor de persoon aan wie je het boek cadeau wil doen.

Die wêreld vier vandag Internasionale Moedertaaldag en Kosmos 94.1 vier natuurlik ons moedertaal, Afrikaans! Ons het gaan aanklop by Unam se departementshoof van geesteswetenskappe en kunste, en ook taalkunde professor Herman Beyer, wat wonder waarheen ons taal op pad is.

"Because the premise of immune checkpoint blockade centers around elevating the immune function, we should always take a great deal of caution around those patients who have high immune risks. Those include patients with autoimmune disorders. That's one of our biggest questions that we ask, usually every consult that we're seeing with solid tumor. 'Do you have any history of autoimmune disorders? Tell me a little bit more about it. Is it being treated? What are your symptoms like?' And then also patients who have undergone organ transplants. Now, interestingly, this does include stem cell transplants," Kelsey Finch, PharmD, BCOP, oncology pharmacist practitioner at Columbus Regional Health in Indiana, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about checkpoint inhibitors. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by February 20, 2027. Kelsey Finch has disclosed a speakers bureau relationship with AstraZeneca. This financial relationship has been mitigated. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to checkpoint inhibitors in the treatment of cancer. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Pharmacology 101 series Episode 273: Updates in Chemotherapy and Immunotherapy Episode 174: Administer Pembrolizumab Immunotherapy With Confidence Episode 139: How CAR and Other T Cells Are Revolutionizing Cancer Treatment ONS Voice articles: Here's Why Oncology Nurses Are Pivotal in Managing Immune-Related Adverse Events Make Subcutaneous Administration More Comfortable for Your Patients Nursing Considerations for ICI-Related Myocarditis Oncology Nurses Navigate the Changing Landscape of Immuno-Oncology Postdischarge ICI Patient Education Eliminates Hospital Readmissions Shorter Administration Times Still Require High-Acuity Care ONS Voice oncology drug reference sheets: Dostarlimab-Gxly Nivolumab and Hyaluronidase-Nvhy Nivolumab and Relatlimab-Rmbw Pembrolizumab and Berahyaluronidase Alfa-Pmph Retifanlimab-Dlwr Toripalimab-Tpzi ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Guide to Cancer Immunotherapy (second edition) ONS course: ONS/ONCC® Chemotherapy Immunotherapy Certificate™ Clinical Journal of Oncology Nursing articles: Immune Checkpoint Inhibitor–Related Myocarditis: Recognition, Surveillance, and Management Immune Checkpoint Inhibitor Therapy: Key Principles When Educating Patients Triple M Syndrome: Implications for Hematology-Oncology Advanced Practice Providers ONS Huddle Cards: Checkpoint Inhibitors Immunotherapy ONS Learning Libraries: Genomics and Precision Oncology Learning Library Immuno-Oncology Learning Library Drugs@FDA package inserts National Comprehensive Cancer Network homepage OncoLink: All About Immunotherapy To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Before immune checkpoint blockade, the two-year overall survival rate in metastatic melanoma was hovering around 10%. After these agents came to market, depending on the trial and the agents used, that number actually increased to about 50%–65%. So, five times the amount of patients were actually living at the two-year mark. Not surprisingly, studies then exploded across several tumor types, leading to approvals in all sorts of cancers, mostly in the solid tumor. But there are a couple hematologic as well. Lung cancer, kidney cancer, head and neck, Hodgkin lymphoma, hepatocellular, the list goes on. So, it's really just transforming the stage IV setting across all tumors, specifically from uniformly fatal prognosis to one where durable responses and long-term survival is also possible." TS 3:03 "There are four different mechanisms officially being used in therapies that are approved by the U.S. Food and Drug Administration (FDA). Those are cytotoxic T-lymphocyte–associated protein 4, programmed cell death protein 1, and programmed cell death ligand 1, which I'm counting as two different mechanisms, even though they somewhat work together. And lymphocyte-activation gene 3 is the fourth one that's in there. So, all these mechanisms impact the T cell in our immune system. The T cell is traditionally responsible for protecting our body from harmful things like bacteria, viruses, and cancer. When the tumor binds to cytotoxic T-lymphocyte–associated protein 4 receptors, that happens on the T cell itself. And that inhibits the activation of the T cells, essentially allowing that tumor to then live. So when developing medications that block this receptor, they noted an added benefit that it actually increased the T-cell proliferation as well as keeping that T cell active. So not only are we not blocking the T cells, we're making them more productive." TS 5:38  "If you have a chance of any sort of tissue rejection, specifically with allogeneic stem cell transplants or where we see that focusing on it, there's a little bit of controversy, mixed bag on opinions as far as autologous stem cell transplants. But it's best to at least exercise a little bit of caution. If they have a chance of organ rejection, is that worth the risk of the therapy that we're looking to give? And then, patients with HIV, any sort of immunologic concerns at baseline that we could potentially worsen." TS 14:37 "As a rule of thumb, with immune checkpoint blockade, regardless of what mechanism you're looking at, if something in your body can get inflamed, that can wind up as an adverse event. So, whenever I talk to my patients, the key word is anything ending in '-itis.' ... The most common adverse events that we end up seeing are dermatitis and hypothyroidism. Immune checkpoint blockade can cause both hyper- and hypothyroidism. Very often, we actually start in the hyper- and then end up, for lack of better words, burning out the thyroid, ultimately leading to a sustained hypothyroidism." TS 18:34 "The half-life of immune checkpoint inhibitors is usually around 30 days, meaning that once these agents are given, the drug will be in the patient's system for up to five months. Specifically, it will probably build month to month, so often we don't even see a lot of our adverse events until month three or four. Usually, when we're that far into treatment, we're not looking for new adverse events in things like chemotherapy. But these drugs do build over time." TS 24:28 "As far as safe handling is concerned, these agents are not chemotherapy. That makes drug compounding and administration pretty straightforward. When looking at the follow-up care, the most important thing, in my opinion, is to engage in meaningful dialogue with your patients. A lot of the side effects can be nonspecific. So, really listening to the patient and evaluating changes in their lifestyle, I think it'll get you far. We usually hark in on the new, worsening, or persistent whenever we're talking to patients because they'll be looking for things as well. So, just having a dialogue of how their life has changed can certainly help." TS 26:17

Wat zit er in vandaag in De 7? Telenet keert na vier jaar afwezigheid terug naar de beurs. Niet die van Brussel, maar Amsterdam. Waarom zetten ze die stap? Carrefour zet nu ook openlijk de deur open voor de verkoop van z'n Belgische winkels. Ons land behoort niet meer tot de kernmarkten van de Franse supermarktketen. Het ziet er naar uit dat er volgend jaar weer marge is voor loonsopslag bovenop de index. Da's omdat de loonkosten in België minder snel stijgen dan in het buitenland. Host: Roan Van EyckProductie: Lara DroessaertSee omnystudio.com/listener for privacy information.

Vandaag bespreken we het boek, Intiem verzet van Josep Maria Esquirol. De ondertitel is: Naar een filosofie van nabijheid Josep Maria Esquirol Calaf (geboren in 1963 in Mediona) is een Catalaanse filosoof, essayist en hoogleraar filosofie aan de Universiteit van Barcelona. Hij leidt de Aporia Research Group, die zich bezighoudt met hedendaagse filosofie en in het bijzonder met de relatie tussen filosofie en psychiatrie. https://en.wikipedia.org/wiki/Josep_Maria_Esquirol_Calaf La resistència intima. Ensayo de una filosofia de la proximidad https://www.youtube.com/watch?v=rcxR_l1_I5E (gesprek) - Engelse ondertiteling aanzetten. Voor mij was het een ingewikkeld boek. Ik had moeite om erdoorheen te komen en heb dan ook niet alles gelezen. Daar zit voor mij ook een soort tweestrijd in, ik denk dat je dit soort boeken niet in één ruk (of in twee weken) moet uit willen lezen. Het heeft ruimte nodig om te herlezen, om te bezinnen en te filosoferen. Tegelijkertijd had ik het boek nooit uitgelezen als we deze deadline niet hadden. Dan was het blijven liggen en had ik veel liever het boek Wachten gelezen van De Wachter. Daar ben ik in begonnen en het leest weg. Lastig vind ik alle filosofen die hij aanhaalt, quotes uit boeken, en met delen is hij het wel eens en met anderen niet. Het voelt soms zinloos wat hij beschrijft voor mij. Ook de woorden die gebruikt worden zijn voor mij niet altijd bekend of duidelijk. Inhoudsopgave De warme maaltijd op tafel (moment) I Ontwrichting en verzet II Het niets en de nihilistische ervaring in kaart gebracht De tuin bewerken (moment) III Terug naar huis IV Lofzang op het alledaagse: hoe eenvoudig het leven kan zijn V Korte medische overpeinzing VI Zelfzorg zonder narcisme VII Niet zwichten voor het dogmatische van de actualiteit Subatomisch zweet (moment) VIII De oceaan of de woestijn? IX De essentie van taal als beschutting X Een metfysica van het verbond De warme maaltijd op tafel (moment) Samenleven staat of valt met samen eten. (past in de Mediterane cultuur) I Ontwrichting en verzet Bestaan is jezelf vormgeven, en daarmee verzet plegen. Leven is jezelf ontplooien (tegenpool bij life coaches van verzet) een persoonlijk uniek pad naar het geluk, overbodige sofisterij - middelmatigheid. Verzet tegen tirannieën is verzet tegen de ontwrichting. Een goed leven is niet het summum. II Het niets en de nihilistische ervaring in kaart gebracht Het nihilisme staat voor een gebrek aan waarden, het besef dat we de betekenis van ons bestaan niet kunnen doorgronden met concepten als doel, eenheid en waarheid. p29 De confrontatie met jezelf: enerzijds sta je oog in oog met het niets, maar anderzijds is het de beste manier om tot rust te komen. p33 De tuin bewerken (moment) Mooi in het verhaal hoe ze de man ontmoeten die de actualiteit niet volgt. Geen grootgrondbezitter, maar wel genoeg om van te leven met zijn kinderen. Door het werk op het land houden ze drie grote rampen van het lijf, de verveling, de ondeugd en de honger. Gedachtenloos werken maakt het leven draaglijk. Zingeving is te vinden in nabijheid. III Terug naar huis Het huis is een veilige plek om naar terug te keren. De beschutting, de rust die intimiteit biedt. Het gaat om bescherming en gastvrijheid. De gifteconomie gaat niet uit van groei, maar van volharding en herhaling. IV Lofzang op het alledaagse: hoe eenvoudig het leven kan zijn In plaats van steeds op zoek gaan naar het buitengewone, ons verwonderen over de eenvoud om ons heen, en leren het te waarderen. p60 en 61 Het gemiddelde leven wordt ondergewaardeerd. Ons bestaan is een verblijf in de nabijheid. V Korte medische overpeinzing VI Zelfzorg zonder narcisme VII Niet zwichten voor het dogmatische van de actualiteit Subatomisch zweet (moment) Dit hoofdstuk begreep ik niet. VIII De oceaan of de woestijn? IX De essentie van taal als beschutting X Een metfysica van het verbond Opvallende lessen uit het boek voor ons: 00:00 intro - een eerste indruk van het boek, het boek leest lastig 08:15 Een reactie is op onze wereld van social media en te veel media. Terug naar de kern, naar minder. 13:05 Samenleven staat of valt met samen eten. 16:10 Leven is je verzetten. 16:35 Onverzettelijk verzet tegen de zelfgenoegzaamheid van de massa. 17:20 Het Nederlandse woord samenleven is de kern van dit verzet. De redzame burger is het tegenovergestelde van samenleven. 18:35 Life coaches die zeggen dat je naar je persoonlijke unieke pad naar geluk moet zoeken, dit is overbodige sofisterij . 19:25 Verzet tegen tirannieën is verzet tegen de ontwrichting. Het glorificeren van het simpele bestaan door Esquirol. 26:10 Solidariteit neemt de vorm van een huis aan, en ongastvrij is geen huis. 27:30 De gifteconomie gaat niet uit van groei, maar van volharding en herhaling, totdat iedereen een huis en te eten heeft. 28:55 In plaats van op zoek te gaan naar het buitengewone, ons verwonderen over de eenvoud om ons heen en leren waarderen. 30:20 Een dagelijks leven dat rijk genoeg is ligt binnen het bereik van de meeste mensen. 36:50 Nadenken, reflectie, is al een vorm van voor jezelf zorgen. 42:25 Het suikerzoete scepsis van huis-, tuin- en keukenintellectuelen. 49:10 Alleen buiten de actualiteit is leven. Bronnen die we genoemd hebben Wij Nihilisten – Hans Schnitzler #boekencast afl 78 Stop chasing happiness – Frank Martela #boekencast afl 133 Infocratie – Byung-Chul Han #boekencast afl 72 Over het verdwijnen van rituelen – Byung-Chul Han #boekencast afl 123 Jaaroverzicht #boekencast 2025 Michel Foucault - Wikipedia Limitarisme – Ingrid Robeyns #boekencast afl 96 Toxisch reich – Sebastian Klein #boekencast afl 122 Komt een land bij de dokter – Michelle van Tongerloo #boekencast afl 114 Hannah Arendt - Wikipedia arts Wico Mulder - Praktijk SALUT Inner Development Goals Filosofie van de kroeg - Hans Schnitzler Luister naar deze aflevering Beluister hier ons gesprek over het boek Intiem verzet Opmerking: ik heb per ongeluk deze aflevering met de verkeerde microfoon opgenomen die wat verder wegstaat. Mijn excuses daarvoor. In een halfuur delen wij dit boek met jou. Een halfuur met kennis die je tot je neemt terwijl je wandelt, loopt of rijdt, bijvoorbeeld. Video van deze aflevering Bekijk ons gesprek op video https://youtu.be/jdKfi565MGo https://youtu.be/jdKfi565MGo Opmerking: ik heb per ongeluk deze aflevering met de verkeerde microfoon opgenomen die wat verder wegstaat. Mijn excuses daarvoor. In deze aflevering bespreken we het boek Intiem verzet In deze aflevering van de Ondernemers Boekencast bespreken we Intiem Verzet: Naar een filosofie van nabijheid van Josep Maria Esquirol (hoogleraar filosofie in Barcelona, leider van de Actoria Research Group rond hedendaagse filosofie en de relatie met psychiatrie). Het boek (Nederlandse vertaling, ca. 185 pagina's leestekst) hebben we als complex en soms moeilijk toegankelijk ervaren, met veel verwijzingen naar andere filosofen en wisselende leesbaarheid per hoofdstuk en tussenteksten (‘momenten'). We bespreken de goed leesbare onderdelen o.a. ‘De warme maaltijd op tafel' en ‘De tuinbewerkers', maar we vinden passages zoals ‘Het subatomische zweet' onbegrijpelijk. De bespreking richt zich op de kernideeën: ‘intiem verzet' als verzet tegen ontwrichting, egoïsme en de ‘heerschappij van de actualiteit' (social media, media-overload en een virtuele wereld), door terug te keren naar het nabije en alledaagse: samen eten, het huis als plek van bescherming en gastvrijheid, de tuin/het werk (met verwijzingen naar kloostertradities en ‘ora et labora'), en aandacht voor solidariteit. We noemen het concept ‘gifteconomie' als kritiek op groei-logica en als volharding en herhaling ‘tot iedereen een huis en te eten heeft', en verbinden dit aan fraternité/solidariteit en aan hedendaagse thema's zoals dakloosheid. Verder komt ‘lofzang op het alledaagse' aan bod (verwondering over eenvoud, waarbij eenvoud niet hetzelfde is als banaliteit) en het hoofdstuk ‘zelfzorg zonder narcisme', waarin reflectie wordt gepresenteerd als zorg voor jezelf zonder egocentrisme. Tom bespreekt het hoofdstuk over taal als beschutting, met Levinas-citaten over taal als contact en een oprecht ‘gaat het goed met je?' als vorm van zorg, en contrasteert dat met oppervlakkige ‘hoe gaat het?'-gesprekken en mediapraat. Het boek eindigt volgens ons met de gedachte dat ‘eenvoudige mensen' dit al lang wisten en dat filosofische reflectie later aansluit, met verzet als het bewaken van verbinding. We sluiten af met de oproep de ‘stekker eruit te trekken' uit actualiteit en routines, en terug te keren naar eenvoud, nabijheid en echte verbinding als basis voor een (her)nieuwde samenleving. Transcript Erno Hannink: [00:00:00] Welkom in de nieuwe Ondernemers Boekencast. Vandaag bespreken we het boek Intiem Verzet. Het boek van Josep Maria Esquirol. De ondertitel is Naar een filosofie van nabijheid. Het boekje hebben we gekregen van Ten Haven. Dankjewel daarvoor. Geregeld door Tom. Laat ik eerst even zeggen, Esquirol dat is een cartelaan. Hij is hoogleraar filosofie aan de Universiteit van Barcelona. En hij leidt de Actoria Research Group. Die is bezig met hedendaagse filosofie en in het bijzonder de relatie tussen filosofie en psychiatrie. Ik heb wel wat meer met filosofie en technologie, daar heb ik wel een paar keer wat dingen van gehoord en naar geluisterd. Maar ik moet zeggen, van de combinatie filosofie en psychiatrie nog niet. Het oorspronkelijke boek, de Spaanse versie, is volgens mij vier jaar geleden uitgekomen. En dit is de Nederlandse vertaling daarvan. Het boek is ongeveer 185 pagina's, het leesgedeelte.

'n Beskuldigende vinger word na twee voormalige presidente gewys weens die versuim om apartheidsmisdade te vervolg. Ons praat oor die sogenaamde agterdeur-privatisering van Eskom. Huldeblyke stroom in ná die dood van die Amerikaanse burgerregteleier, eerwaarde Jesse Jackson.

Volendam verrast vriend, vijand en alle Veermannen in de omgeving, Feyenoord werkt zich met alle moeite langs de geparkeerde De Busscher, en Ajax viert Belgische septemberfeesten in februari. Verder is Ron Jans weer helemaal Ron Jans, vonden de winterspelen plaats in Rotterdam en bestaat het carnaval-effect bij NAC. Het is maandagavond, op naar een nieuwe aflevering van De Derde Helft.✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

"It's important to clarify that most patients will experience and at least some side effects—and often several. So prevention really means reducing severity, complications, and long-term impact rather than avoiding side effects altogether. This process starts before radiation begins and continues throughout the treatment and includes dental evaluation, baseline swallowing assessments, and thorough patient education," ONS member Astrid Amoresano, RN, OCN®, lead oncology nurse specialist at New York Proton Center in New York, NY, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about side effects of radiation for head and neck cancer. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by February 13, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to radiation side effects in people with head and neck cancer. Episode Notes  Complete this evaluation for free NCPD.  ONS Podcast™ episodes: Cancer Symptom Management Basics series Episode 301: Radiation Oncology: Side Effect and Care Coordination Best Practices Episode 128: Manage Treatment-Related Radiodermatitis With ONS Guidelines™ ONS Voice articles: Highly Localized, Precision Radiation Therapies Require Nurses to Drive Care Coordination, Patient Education IMRT Shows Similar Quality-of-Life Outcomes to Proton Therapy in Head and Neck Cancer How to Handle Even the Worst Radiation Therapy Side Effects ONS book: Manual for Radiation Oncology Nursing Practice and Education (fifth edition) ONS courses: ONS/ONCC® Radiation Therapy Certificate™ ONS Oncology Symptom Management Clinical Journal of Oncology Nursing articles: The Role of Advanced Practice Providers in Radiation Oncology in 2025 Systematic Review of Malnutrition Risk Factors to Identify Nutritionally At-Risk Patients With Head and Neck Cancer Effects of a Nurse-Initiated Telephone Care Path for Pain Management in Patients With Head and Neck Cancer Receiving Radiation Therapy Radiation-Induced Skin Dermatitis: Treatment With CamWell® Herb to Soothe® Cream in Patients With Head and Neck Cancer Receiving Radiation Therapy ONS Radiation Learning Library ONS Symptom Intervention Resources ONCC: Radiation Oncology Certified Nurse (ROCN™) American Cancer Society CA: A Cancer Journal for Clinicians article: American Cancer Society Head and Neck Cancer Survivorship Care Guideline Cancer Survivors Network: Head and neck cancer Head and neck cancer resources Radiation therapy resources American Society of Radiation Oncology National Cancer Institute: Common Terminology Criteria for Adverse Events (CTCAE) National Comprehensive Cancer Network To discuss the information in this episode with other oncology nurses, visit the ONS Communities. To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Many tumors in the region are very radiosensitive, and radiation can be used either as definitive treatment or after surgery to reduce the risk of reoccurrence, but in many cases, radiation is combined with chemotherapy to improve local control. Because so many vital structures are located in this small complex area, radiation allows us to treat the cancer while minimizing the need for extensive or disfiguring surgery." TS 2:40 "The most common acute side effects of head and neck radiation: effects to the mouth, the throat, the skin, and the energy level. Patients often experience a mucositis, pain or sore throat, difficulty swallowing, dry mouth, or thick saliva, and taste changes. Skin irritation and redness in the treatment field is also common and can progress to dry and moist desquamation. Fatigue is another frequent side effect and tends to build as treatment progresses. Emotional and psychological distress are also very common in this patient population and can have an impact on daily function and quality of life. Side effects usually develop gradually, often beginning in the second and third week of radiation and may be more severe or have an earlier onset in patients receiving concurrent chemotherapy." TS 4:02 "Pain management is essential so patients can continue eating and drinking. Supporting the energy level and maintaining hydration are also key, as fatigue and dehydration can significantly worsen other side effects. Oral care protocols help manage mucositis and nutrition support may include supplements or enteral feeding if needed." TS 11:24 "Sexual health might not be the first thing nurses think of in regard to head and neck radiation. … But even though radiation for head and neck cancer doesn't involve the reproductive organs, it can still have a significant impact on sexual health and intimacy. Like fatigue, pain, dry mouth, changes in speech and visible changes in appearance can all affect body image and relationships." TS 14:52 "One of the common misconceptions is that side effects end when radiation ends. In reality, some effects peak afterward or become long term. Xerostomia, or dry mouth, and taste changes are good examples. While some patients improve, others adjust to a new normal where dry mouth and altered taste are permanent." TS 19:53

Zo! Dat was niet alleen de langste, maar voor velen ook meteen de beste State of Play ooit! Met meer dan 25 titels op het menu stond deze showcase vooral bij Simon dik op z'n buik geschreven. Samen met Martin en Jacco blikt hij terug op (bijna) alles wat voorbij kwam, en duiken ze dieper in onder andere: God of War: Sons of Sparta, Kena: Scars of Kosmora, Castlevania: Belmont's Curse, Project Windless en natuurlijk de aangekondigde John Wick-game! Benieuwd wat de jongens ervan vonden? Check dan als de wiedeweerga deze speciale extra aflevering, baklap!00:00 Intro02:20 Ons oordeel09:20 Project Windless11:35 Resident Evil Requiem13:35 Kena: Scars of Kosmora19:00 Legacy of Kain: Defiance Remastered / Ascendance22:45 Yakoh Shinobi Ops27:25 Dead or Alive31:45 Control: Resonant36:05 Beast of Reincarnation37:15 Neva: Prologue39:05 Star Wars: Galactic Racer42:35 Metal Gear Solid Collection 245:15 Castlevania: Belmont's Curse49:15 Silent Hill: Townfall52:10 John Wick54:35 God of War Trilogy Remake56:35 God of War: Sons of Sparta01:03:00 Horizon Hunters: Gathering01:04:45 Onze Reddit-aankondiging01:06:45 Outro

Die Weermag gaan op die Kaapse Vlakte en in Gauteng ontplooi word om bendegeweld te help bekamp. Bek-en-klouseer is as nasionale ramp verklaar, en nou eis die Menseregtekommissie dat dieselfde oor watertekorte gebeur. Ons praat met die 20 jarige Kyla Reynecke van die vroue-Proteas oor haar ongelooflike prestasie teen Pakistan.

Marit is vijftien kilo afgevallen en dat succes voelt nog kwetsbaar. Als je als kind veel bent gepest, vlieg je het liefst onder de radar en opmerkelijk gewichtsverlies voelt dan onveilig. Maar ze wil uit de schaduw komen van haar oude overlevingsmechanisme. Ze wil haar succes bevestigen en haar Etenslessen met je delen. Ze wil juist open zijn over haar verleden nu ze heeft ontdekt dat dit een grote vrijheid brengt. De kracht van schaamteloosheid herkennen we beide: als je niets te verbergen hebt, kan je ook nergens op betrapt worden.De Etenslessen van Marit zijn helend en haar wijsheid gaat je helpen als je soms last hebt van donkere gedachten over jezelf. Ik ben onder de indruk van wie ze nu is en hoe ze alles aanpakte, om de stralende toekomst te bouwen waarin ze nu leeft. Ons gesprek heeft me geraakt en zal jou ook raken. Hier zijn de Etenslessen van Marit. Ik dacht dat ik te beschadigd was. Luister nu en klik hier voor de volledige blog en omschrijvingBestel hier jouw exemplaar van het boek Etenslessen →Mentioned in this episode:Gratis Les Verlies gewicht dat niet meer terugkomt

Wat zit er in De 7 vandaag?Is de Europese industrie op weg naar de redding? Onze expert maakt de balans op van de industrietop gisteren in Antwerpen, en blikt vooruit op die in Alden Biesen, later vandaag.Ons land werkt aan een wet waarmee schepen van de Russische schaduwvloot eindelijk zouden kunnen worden onderschept.En is jouw job in gevaar door AI? Meer dan 4 op de 10 Belgen hebben een 'AI-gevoelige' functie. Een rapport van de Hoge Raad voor Werkgelegenheid benoemt de jobs die 't grootste risico lopen. Host: Bert RymenProductie: Roan Van EyckSee omnystudio.com/listener for privacy information.

Gäster: Linus Nordström, Isak Jansson För 90SEK/mån får du 5 avsnitt i veckan:4 Vanliga AMK MORGON + AMK FREDAG med Isak Wahlberg Se till att bli Patron via webben och inte direkt i iPhones Patreon-app för att undvika Apples extraavgifter:Öppna istället din browser och gå till www.patreon.com/amkmorgon Gå på Uddet. på Deglabbet, onsdagar i Stockholm!Säg "AMK" i dörren Ons 11/2 18:00 så kommer ni in gratis!https://www.ticketmaster.se/artist/uddet-biljetter/1349134 Gå på Isaks föreställning "Tre Sagor och en Begravning"https://isakjansson.com/shower/tre-sagor-och-en-begravning/ Relevanta länkar: ...Super Bowl-reklamernahttps://www.yahoo.com/entertainment/articles/super-bowl-2026-ads-ranked-041720097.html ...Kid Rocks half time showhttps://www.dailymail.co.uk/sport/nfl/article-15541453/kid-rock-lip-sync-fail-super-bowl.html https://www.hollywoodreporter.com/music/music-news/kid-rock-turning-point-halftime-show-1236497694/ https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcTl_pSHaGONxFC6udes9dkDLSSPu_nIi8qHHOlASP4yHT4omqZjpTgmsrBCOVWAUbWFiVt2e1ORhSd2vAP3PIhDzEbcacgpUlIelDTvi5BO&s=10 https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcTDByvnnd3ls4CvEFbrTwsLSPHew4XmHGDcdg4Y3qAswZ1adSWzYONnDGfp5nICtTVEzlMrQf7q0tvl4-gWlqD9ruk7MkuAJMYa5ziuIL7Gdg&s=10 https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcTq-W6h-xCfFgvdXjH_McOdsNTppiYjp-PlJBJ2zI9_KF_2VirheXCJ3Y7h47W-ZIKY4RsNFNgEjlfa-iSnpj9BnOdm0_5U05nCR47Gqey2&s=10 ...Drake Mayehttps://en.wikipedia.org/wiki/Drake_Maye ...Linsey Vonns comecackhttps://www.svt.se/sport/alpint/lindsey-vonn-flog-ut-efter-ett-par-sekunder ...Johannes Høsflot Klæbohttps://sv.wikipedia.org/wiki/Johannes_H%C3%B8sflot_Kl%C3%A6bo ...Israel i OShttps://www.aftonbladet.se/senastenytt/ttsport/sport/a/L41v69/burop-nar-israels-os-trupp-presenterades https://www.aftonbladet.se/sportbladet/a/xr8R68/os-israels-mardrom-inbrott-hos-boblaget ...Skeletonhttps://www.svt.se/nyheter/video/b65ea6f51d98c567-sa-funkar-skeleton/pnh6b9 ...vattenrutschbane-Patrikhttps://www.instagram.com/barometern/reel/DUa-Yt3DDG7/ ...Haitis första skidåkarehttps://www.svt.se/sport/langdskidor/har-skriver-stevenson-savart-historia-blir-haitis-forsta-akare-i-vinter-os ...Raygunhttps://tenor.com/sv/view/raygun-raygunn-raygun-breakdance-raygun-breakdancing-breakdance-raygun-gif-3035521202497175510 ...bobfailenhttps://www.facebook.com/watch/?v=3884653894999646 ...det curlade fikafejsethttps://www.svt.se/sport/curling/lag-wrana-klart-for-os-semifinal-trots-forlust ...Kakoa-Wolf Momoahttps://www.instagram.com/nakoaawolf.momoa/?hl=en ...Trumps apvideohttps://omni.se/trump-video-med-obama-som-apa-borttagen-efter-kritik/a/wr87aP ...George Busch-klippethttps://www.tiktok.com/@ryanhern94/video/7604319371409853709?is_from_webapp=1&sender_device=pc ...Moltbookhttps://www.moltbook.com/ ...A Knight of the Seven Kingdomshttps://www.imdb.com/title/tt27497448/ ...Melaniahttps://www.moviezine.se/nyheter/melania-slar-rekord-pa-rotten-tomatoes-aldrig-har-kritiker-och-publik-varit-mindre-overens https://www.di.se/nyheter/melania-trumps-lon-for-sagade-filmen-300-miljoner/ Låtarna som spelades var:Pick Me Up - Gabby BarrettBawitdaba - Kid Rock Alla låtar finns i AMK Morgons spellista här:https://open.spotify.com/user/amk.morgon/playlist/6V9bgWnHJMh9c4iVHncF9j?si=so0WKn7sSpyufjg3olHYmg

PSV goedschiks langs FC Groningen, Van Persie blijft aanmodderen maar wint wel, en Ajax en AZ delen punten in Grimterim-derby. Verder pakte FC Twente niet alleen expected points, moest het NAC-publiek de elfde man zijn en hebben wij een figuurlijk zwaargewicht in ons midden. Het is maandagavond, op naar een nieuwe aflevering van De Derde Helft met debutant WILLEM VISSERS. ✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

"You also want to deal with patient preferences. We do want to get their disease under control. We want to make them live a long, good quality of life. But do they want to come to the clinic once a week? Is it a far distance? Is geography a problem? Do they prefer not taking oral chemotherapies at home? We have to think about what the patient's preferences are to some degree and kind of incorporate that in our decision-making plan for treatments for relapsed and refractory myeloma," Ann McNeill, RN, MSN, APN, nurse practitioner at the John Theurer Cancer Center at Jersey Shore University Medical Center in Neptune, NJ, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about multiple myeloma treatment considerations. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.5 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by February 6, 2027. Ann McNeill has disclosed a speakers bureau relationship with Pfizer. This financial relationship has been mitigated. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the treatment of multiple myeloma. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Episode 398: An Overview of Multiple Myeloma for Oncology Nurses Episode 395: Pharmacology 101: Monoclonal Antibodies Episode 372: Pharmacology 101: Proteasome Inhibitors ONS Voice articles: Effective Care Transitions Are Essential for New Multiple Myeloma Treatments New Multiple Myeloma Treatments Present New Challenges in Side Effect Management Reduce Racial Barriers and Care Inequities for Black and African American Patients With Multiple Myeloma ONS Voice FDA approval alerts ONS Voice oncology drug reference sheets: Belantamab mafodotin-blmf Daratumumab Motixafortide Selinexor Clinical Journal of Oncology Nursing articles: Journey of a Patient With Multiple Myeloma Undergoing Autologous Stem Cell Transplantation Optimizing Transitions of Care in Multiple Myeloma Immunotherapy: Nurse Roles Oncology Nursing Forum article: Facilitators of Multiple Myeloma Treatment: A Qualitative Study ONS books: Hematopoietic Stem Cell Transplantation: A Manual for Nursing Practice (third edition) Multiple Myeloma: A Textbook for Nurses (third edition) ONS course: ONS Hematopoietic Stem Cell Transplantation™ ONS Huddle Cards: Financial Toxicity Hematopoietic Stem Cell Transplantation (HSCT) Monoclonal Antibodies ONS Hematology, Cellular Therapy, and Stem Cell Transplantation Learning Library American Society of Clinical Oncology (ASCO)–Ontario Health: Treatment of Multiple Myeloma Living Guideline International Myeloma Foundation: Clinical Trials Fact Sheets Clinical Trial Support Resource Library Multiple Myeloma Research Foundation resource: Treatments for Multiple Myeloma To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Typically for our first-line therapies, we use certain classes of drugs and some of them are proteasome inhibitors like bortezomib and carfilzomib. We also have IMiDs or immunomodulatory agents like thalidomide, lenalidomide, and pomalidomide. We have monoclonal antibodies, anti-CD38 monoclonal antibodies. Of course, we can never talk about treatment for myeloma without mentioning dexamethasone. It is an integral part of our treatment regimen. Most of our frontline therapies now are not just a single agent. They're not even doublets anymore. Typically, they're triplet therapies. And now in 2026, it's leaning more toward quadruplet therapies. By that, I mean you're taking a proteasome inhibitor, an immunomodulatory drug, dexamethasone, and an anti-CD38 monoclonal antibody all together to present patients with a good chance their induction therapy will lead to a good chance of them responding to treatment." TS 4:25 "[With] myeloma labs, there should be some indication after each cycle of therapy that the treatment is working. So, you don't have to do a whole myeloma panel, but maybe getting a monoclonal protein spike, maybe getting a free light chain assay, or maybe an immunoglobulin G or immunoglobulin A level, just to see if the treatment is working. So, those labs are crucial to determine whether the therapies are working. And again, the lab improvements usually correlate with the clinical presentation of the patient." TS 11:01 "There are active clinical trials ongoing with drugs like cell mods. Cell mods are the new oral anticancer agents for myeloma that have shown great promise with efficacy and safety profiles. And then there are other combinations that are showing a lot of promise. So, drugs that are already approved by the U.S. Food and Drug Administration (FDA). And I'm talking about pairing anti-CD38 monoclonal antibodies with bispecific T-cell engagers. If you do that, there has been some evidence that these combinations are very efficacious and responses are durable. And there are ongoing clinical trials and studies being done right now to see if these can be FDA-approved to pinpoint where they are as far as in comparison to other treatments." TS 20:10 "I always tell patients to try to participate in safe, and I want to stress safe, physical activity. So, I tell patients, the more you sit on the couch or you sit in the chair for most of the day, that unfortunately will make your pain worse. So, trying to get up and about and doing some physical activity, such as getting a physical therapy evaluation and a treatment program, no matter how passive or mild or gentle it is, can really help these patients with bone pain." TS 26:10 "I think it's important to realize that myeloma has had amazing advances in science, research and treatments. I think that all of these things coming together, all the science and clinical trials and everything like that, has led to a significant increase in overall survival of our patients, which ultimately is a great thing. We want patients to live longer and they're living longer with a very good quality of life. So, I think it's important to realize that myeloma is very well studied, very well researched, and it's still ongoing with many, many clinical trials." TS 36:04

De inflatie is in januari gedaald naar 2,4 procent, blijkt uit de eerste raming van het CBS. Dat is welkom, zegt macro-econoom Edin Mujagić, maar volgens hem is het gevaar nog niet geweken: ‘Ons land bevindt zich nog steeds in code rood wat betreft inflatie.’ Je legt een link tussen de inflatie en de ijzel van vandaag? Vanmorgen hoorde ik een medewerker van Rijkswaterstaat zeggen dat sneeuw voorspelbaar is, maar ijzel niet. Je kunt kilometerslang rijden zonder problemen en ineens is het glad. Met inflatie is dat eigenlijk net zo. Je kunt vaak het gevoel hebben dat er niets aan de hand is, bijvoorbeeld na zo’n inflatiecijfer, maar voordat je het weet sta je weer op glad ijs. See omnystudio.com/listener for privacy information.

PSV verlengt met Peter Bosz én de landstitel, de fluwelen revolutie van Cruijff werpt nog geen vruchten af, en AZ had geen idee hoe NEC zou spelen. Verder heeft Faber zichzelf streng toegesproken, pakt FC Twente het volgende expected point en zet de opmars van de Spartamars voort. Het is maandagavond, op naar een nieuwe uur durende aflevering van De Derde Helft samen met MICHIEL DE HOOG! ✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

"Radioimmunoconjugates work through a dual mechanism that combines immunologic targeting with localized radiation delivery. The monoclonal antibody components bind to specific tumor-associated antigens such as CD20, expressed on malignant B cells. Once found, the attached radioisotope delivers beta radiation directly to the tumor, causing DNA damage and cell death," Sabrina Enoch, MSN, RN, OCN®, CNMT, NMTCB (CT), theranostics clinical specialist at Highlands Oncology in Rogers, AR, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about radioimmunoconjugates. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.25 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by January 30, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge in the history of, the mechanism of action of, and the use of radioimmunoconjugates in the treatment of cancer. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Pharmacology 101 series Episode 377: Creating and Implementing Radiopharmaceutical Policies and Procedures Episode 301: Radiation Oncology: Side Effect and Care Coordination Best Practices Episode 298: Radiation Oncology: Nursing's Essential Roles ONS Voice articles: Interprofessional Collaboration Reduces Time to Neutropenia Antibiotic Administration Radiopharmaceuticals and Theranostics Offer New Options for Oncology Nurses to Transform Cancer Care Radiopharmaceuticals Pack a One-Two Punch Against Cancer Safety Is Key in Use of Radiopharmaceuticals Telehealth Has Value During Radiotherapy, Patients Say ONS Voice oncology drug reference sheets: Lutetium Lu 177 dotatate Lutetium Lu 177 vipivotide tetraxetan Radium 223 dichloride Sodium iodide-131 Strontium chloride Sr-89 ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Manual for Radiation Oncology Nursing Practice and Education (fifth edition) ONS courses: ONS/ONCC® Chemotherapy Immunotherapy Certificate™ ONS/ONCC® Radiation Therapy Certificate™ Clinical Journal of Oncology Nursing articles: Radiopharmaceutical Safety: Making It Easy Targeted Radionuclide Therapy: A Theranostic Approach to Cancer Therapy ONS Huddle Cards: Radiobiology Radiopharmaceuticals ONS Learning Libraries: Immuno-Oncology Radiation ONS Symptom Interventions for Prevention of Bleeding Drugs@FDA package inserts To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Radioimmunoconjugates are a specialized subset of radiopharmaceuticals designed to combine the specificity of monoclonal antibodies with the cytotoxic power of radiation. ... Early development focused on B-cell malignancies, particularly non-Hodgkin lymphoma." TS 1:51  "An important concept for nurses to understand is the crossfire effect, where radiation can affect nearby tumor cells, even though not every cell expressed has the target antigen. This helps explain why these agents can be effective even in heterogeneous tumors." TS 3:40 "At present, 90 Y-ibritumomab tiuxetan is the only radioimmunoconjugate approved by the U.S. Food and Drug Administration (FDA) in clinical use. Historically, iodine-131 tositumomab played a major role in establishing these therapy classes, but it's also useful to contrast radioimmunoconjugates with other radiopharmaceuticals, such as iodine-131 therapies, which a lot of places do at this time, used for thyroid diseases, or radium 223, used for metastatic prostate cancer. Unlike those agents, radioimmunoconjugates rely on antibody-mediated targeted rather than physiologic uptake or bone affinity." TS 4:55 "I just try to explain to [patients] that radiation exposure is like being next to a flame. The further you are away, the less heat you get, the less exposure you get. These patients can be radioactive for three days, seven days—it just depends on how fast they excrete it through their bodies with half-life exposure." TS 9:33 "While only one agent is currently approved, the principles established by radioimmunoconjugates continue to guide development for newer targeted radiopharmaceuticals. Emerging agents aim to improve targeting, reduce toxicity, and expand indications beyond hematologic malignancies. This evolution underscores the importance of nursing education in this rapidly changing field." TS 10:41 "Radioimmunoconjugates represent an important bridge between traditional oncology treatments and the future of targeted therapies. Oncology nurses play a vital role in ensuring safe delivery, patient understanding, and collaboration between multidisciplinary teams. So, it's very important to educate and also stay up to date on evidence-based practices." TS 13:12

Alleen als de mensensmokkelroutes worden afgesloten zal de ongereguleerde immigratie afnemen. “Daar ziet het onder de nieuwe coalitie niet naar uit”, verzucht Wierd Duk in een nieuwe aflevering van de podcast Het Land van Wierd Duk. “Ons land zal nog verder verdeeld raken”. Verder in de podcast: waarom verzwijgen zoveel media hen onwelgevallige feiten? En: agenten in Utrecht moeten vrezen voor Jihadisten.See omnystudio.com/listener for privacy information.

De broertjes zijn veilig geland in onze studio, glijden PSV en Schouten na midweekse zeperd opnieuw uit, Feyenoord wint wedstrijd maar verliest meer spelers en Youri is Volendam de baas in de ArenA. Verder mag Jeroen Zoet alles met z’n handen pakken, pakt Joel Drommel alles, wint NEC de tweede een-letter-verschil-derby op rij en zit Tim als een soort bloedzuiger vast aan de gast van deze week, om er alle informatie ooit uit te zuigen. Onze gast deze week weet echt alles, Adriaan ter Braack ook wel bekend als Sjamadriaan schuift aan in een nieuwe aflevering van De Derde Helft.✉️ Op vrijdag kunnen jullie met ons via Substack vooruitblikken op het aankomende Eredivisie-weekend. Gijs, Tim, Snijboon, Pepijn en RogierPablo zullen hier allemaal één ding delen waar ze naar uitkijken in de aankomende speelronde. https://substack.com/@dederdehelft

"The United States does not have a national cancer registry. We have a bunch of state registries. Some of those registries do collaborate and share information, but the issue is the registries that do exist typically do not report cancer by occupation. So, we cannot get our arms around the potential work-relatedness of the health outcome given the current way the state registries collect information. What we're trying to set up, is a way to make what is currently an invisible risk, visible," ONS member Melissa McDiarmid, MD, MPH, DABT, professor of medicine and epidemiology and public health director of the division of occupational and environmental medicine at the University of Maryland School of Medicine in Baltimore, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about the University of Maryland School of Medicine Hazardous Drug Safety Center Exposure Registry. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by January 23, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge in the incidence of hazardous drug exposure and the tracking and reporting of healthcare worker exposures. Episode Notes  Complete this evaluation for free NCPD. University of Maryland School of Medicine Hazardous Drug Safety Center Exposure Registry information sheet ONS Podcast™ episodes: Episode 330: Stay Up to Date on Safe Handling of Hazardous Drugs Episode 308: Hazardous Drugs and Hazardous Waste: Personal, Patient, and Environmental Safety Episode 209: Updates in Chemo PPE and Safe Handling ONS Voice articles: Hazardous Drug Surface Contamination Prevails, Despite More Diligent PPE National Hazardous Drug Exposure Registry Safeguards Oncology Professionals NIOSH Releases Its 2024 List of Hazardous Drugs Safe Handling—We've Come a Long Way, Baby! Strategies to Promote Safe Medication Administration Practices Surfaces in Patient Bathrooms Often Contaminated With HDs, Despite Use of Plastic-Backed Pads ONS books: Safe Handling of Hazardous Drugs (fourth edition) Safe Handling of Hazardous Drugs Quick Guide™ ONS course: Safe Handling Basics Clinical Journal of Oncology Nursing articles: Hazardous Drug Exposure: Case Report Analysis From a Prospective, Multisite Study of Oncology Nurses' Exposure in Ambulatory Settings Personal Protective Equipment Use and Surface Contamination With Antineoplastic Drugs: The Impact of the COVID-19 Pandemic Sequential Wipe Testing for Hazardous Drugs: A Quality Improvement Project The Use of Plastic-Backed Pads to Reduce Hazardous Drug Contamination Oncology Nursing Forum articles: Ensuring Healthcare Worker Safety When Handling Hazardous Drugs Factors Influencing Nurses' Use of Hazardous Drug Safe Handling Precautions Other ONS resources: ONS Safe Handling of Hazardous Drugs Quick Guide Introduction to Safe Handling Huddle Card Safe Handling of Hazardous Drugs Learning Library Hematology/Oncology Pharmacy Association (HOPA) course: Safe Handling of Hazardous Drugs National Institute for Occupational Safety and Health (NIOSH) List of Hazardous Drugs in Healthcare Settings, 2024 To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "We thought that in order to answer some of the unclear questions about health risk, we would set up an exposure registry, in this case, for oncology personnel who handle the drugs. This would then create a cohort that we could ask questions to. For example, we could try to characterize whether there is a cancer excess in this group. Or characterize the reproductive abnormalities in excess that people are experiencing." TS 6:21 "It's sort of counterintuitive that the healthcare industry, whose mission itself is care of the sick, is a high-hazard industry. We typically think about the risk as being from infectious diseases, and certainly we've all lived in our practice lifetime through some examples of that. Even before COVID-19, some of us were doing preparation for Ebola and that sort of thing. So, we're kind of used to that. But the hazards that you kind of grew up with, we've routinized or normalized handling group one, human carcinogens, which a number of these drugs are—it's just something we do every day. Well, it is, but we have to do it with respect and with care every day. And I think sometimes in that routineness of it, we have sort of lost sight of the vigilance that we need to maintain." TS 11:19 "It's very easy in the life cycle of a drug in an organization to do something that doesn't just impact you, but unknowingly, you've contaminated a surface for somebody who comes behind you. Who maybe doesn't have plastic protective equipment on because something that got contaminated shouldn't have been contaminated in the first place. If we could all be thinking of it as more of a team sport, especially in terms of safe handling, that our disposition and drug handling affects not just us and our health, but those of our colleagues." TS 24:47 "For the job history pieces, we ask what year you started, what year you stopped, and we ask about estimations of handling. So we'll be able to come up with either a duration or some kind of metric for the intensity and duration of your handling history, which will then permit us to sort the population who completed the survey into sort of low, medium, high. And we'll see whether the health outcomes that are being reported are influenced by that drug handling history." TS 27:45 "The idea that we aren't exposed to the same therapeutic dose we give to our patients is absolutely true. However, the dosing schedule to them versus us is very different, and we are exposed frequently, if not daily, to very small concentrations. They don't reach a cytotoxic dose necessarily, but we do know from a lot of studies that either ourselves or our colleagues are taking up drug from contaminated work environments. And you've probably seen there is an awful lot of intermediate evidence looking at genotoxic insult in pharmacists and nurses who handle the drugs. So clearly we're showing uptake and we're showing that there are biologically plausible, concerning measures that are taking place in us. So, I think that we need to come back and circle around the idea that we need to have deep respect for the toxicity of these agents." TS 35:03

"[Multiple myeloma] is very treatable, very manageable, but right now it is still considered an incurable disease. So, patients are on this journey with myeloma for the long term. It's very important for us to realize that during their journey, we will see them repeatedly. They are going to be part of our work family. They will be with us for a while. I think it's our job to be their advocate. To be really focused on not just the disease, but periodically assessing that financial burden and psychosocial aspect," Ann McNeill, RN, MSN, APN, nurse practitioner at the John Theurer Cancer Center at Jersey Shore University Medical Center in Neptune, NJ, told Lenise Taylor, MN, RN, AOCNS®, TCTCN™, oncology clinical specialist at ONS, during a conversation about multiple myeloma. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  Earn 0.75 contact hours of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by January 16, 2027. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learners will report an increase in knowledge related to the pathophysiology and diagnosis of multiple myeloma. Episode Notes  Complete this evaluation for free NCPD. ONS Podcast™ episodes: Episode 332: Best Nursing Practices for Pain Management in Patients With Cancer Episode 256: Cancer Symptom Management Basics: Hematologic Complications Episode 192: Oncologic Emergencies 101: Hypercalcemia of Malignancy ONS Voice articles: AI Multiple Myeloma Model Predicts Individual Risk, Outcomes, and Genomic Implications Cancer Mortality Declines Among Black Patients but Remains Disproportionately High Financial Navigation During Hematologic Cancer Saves Patients and Caregivers $2,500 Multiple Myeloma: Detecting Genetic Changes Through Bone Marrow Biopsy and the Influence on Care Multiple Myeloma Prevention, Screening, Treatment, and Survivorship Recommendations Nurse-Led Bone Marrow Biopsy Clinics Truncate Time for Testing, Treatment Diagnose and Treat Hypercalcemia of Malignancy ONS books: BMTCN® Certification Review Manual (second edition) Multiple Myeloma: A Textbook for Nurses (third edition) Clinical Journal of Oncology Nursing articles: African American Patients With Multiple Myeloma: Optimizing Care to Decrease Racial Disparities Music Intervention: Nonpharmacologic Method to Reduce Pain and Anxiety in Adult Patients Undergoing Bone Marrow Procedures Other ONS resources: Financial Toxicity Huddle Card Hypercalcemia of Malignancy Huddle Card Hematology, Cellular Therapy, and Stem Cell Transplantation Learning Library American Cancer Society article: What Is Multiple Myeloma? Blood Cancer United educational resources page International Myeloma Foundation homepage Myeloma University homepage Multiple Myeloma Research Foundation (MMRF) article: Understanding Multiple Myeloma To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "Epidemiologically, myeloma is a cancer of older adults. The median age is about 69. It is more common in men than women. It's a ratio of about three men to two women that are diagnosed. It is much more common in people of African American descent with increasing global incidence linked to aging populations. Although, the highest rates are in high-income countries. So, if we look at some of the risk factors, and several have been identified, including MGUS. MGUS is a benign precursor of myeloma, and it stands for monoclonal gammopathy of undetermined significance. Older age is also a risk factor, although we do see patients that are younger who are diagnosed with myeloma." TS 1:54 "Bone pain, specifically in the back, and fatigue, are very common symptoms that relate to things that are going on behind the scenes with myeloma. But also, patients can be bothered by frequent and long-lasting infections. So, they find that they get sick more frequently than their family and friends, and they take a longer time to recover. That could also be a presenting sign. I think there can be some presenting signs and symptoms related to electrolyte abnormalities, especially in later stages. They might be nauseated, vomiting, or constipated. Also, signs and symptoms related to cytopenias. You have to remember that this is a bone marrow cancer. So, we do have some problem with development of normal blood cells. So, we can see not only infections, but bleeding issues related to thrombocytopenia and factors related to anemia from low red blood cell counts." TS 7:15 "About 20%–25% of our patients who are diagnosed are asymptomatic. They have no symptoms. They're living their lives, they're going to work or they're traveling, playing golf on the weekends, taking care of their children or grandchildren. They are just living their lives. And at times, they go to the primary care physician and then they're referred to a hematologist-oncologist, and they're pretty surprised when they're sent to a cancer center. The way they are diagnosed in this matter is that their routine lab work, the complete blood cell count may be normal, there may be some slight differences in their hemoglobin. But what we see in the chemistry, the complete metabolic panel, is an elevation in their total protein and or an elevation of the total globulins." TS 9:22 "The bone marrow biopsy serves many purposes. You want to determine the percentage of bone marrow plasma cells. So, you want to get the degree of plasmacytosis. And then you want to do really specific tests on those plasma cells. So, you want to isolate the malignant plasma cells and determine, via analysis. So, we do the karyotype, chromosomal studies, fluorescence in situ hybridization (FISH) studies, immunohistochemistry studies, and molecular studies. All of these studies are looking for specific genetic changes in the myeloma cells—looking for translocations or deletions. And it's very important to get that information because we can put patients in a category of having standard-risk disease versus high-risk disease. And that can give us a better picture of what this patient's journey with myeloma may look like." TS 13:41 "When I used to work in lymphoma, I spoke with the physicians who were lymphoma specialists, and they said that they foresee a future in having these assays that detect circulating tumor cells actually take the place of imaging studies like restaging positron-emission tomography (PET), computed tomography (CT) scans. So, it's really amazing, these tests that are on the market now and maybe not as widespread as we'd like, but there's a lot of nice assays out there that will become more popular and used more commonplace in the future that I think are going to help identify myeloma more precisely. ... If you think about myeloma, even with measurable residual disease (MRD), MRD for leukemia, for lymphoma, you take a blood sample, you test it for MRD. For myeloma, you need a bone marrow biopsy. You need a bone marrow sample. You can't do MRD on a blood sample for myeloma. Not yet. But if we perfect these assays and we can eventually detect this, then you're looking at a whole new ballgame. You can even perfect your MRD testing as well. So, it's a very exciting time for some of these heme malignancies." TS 28:09

2026 is a big year for Johnny JR as he sets his sights on winning the London Marathon. And with Dave lacing up his cheating shoes to pound the P of London's streets as well, the team have quezzies.Luckily today's episode features a man who is more than capable of answering said quezzies: friend of the show and running guru Ben Parkes. It's his job to help John hack the London Marathon. Godspeed Ben.But fear not, it's not all running chat. Elis has been on the TV, John is (like Meatloaf) out of hell, and there's a cornucopia of call centre celeb stories to read.Keep your ears peeled for some fine Mad Daddery featuring ancient ONS maps, and the team imagine how John would fare on I'm A Celebrity.Reader of this description, send us an email! The address is elisandjohn@bbc.co.uk and the WhatsApp is 07974 293 022.