Podcasts about Higgs

In this special live episode of Owl Have You Know, James Weston, the senior associate dean for degree programs and Harmon Whittington Professor of Finance, reflects on his 25 years at Rice University.Join James and host Maya Pomroy '22 as they explore his journey from the Federal Reserve to Rice Business, the evolution of the school over the past two and a half decades, and his vision for the future of the university. They also dive deep into his groundbreaking research on racial disparities in auto loan pricing — a study that uncovered significant biases against minority borrowers. Plus, get the inside scoop on his experience running a bar in Rice Village.Episode Guide:01:20 James Weston's Career Journey04:25 Early Career and Mentorship08:56 Teaching Philosophy and Student Relationships13:52 Research on Auto Loans and Discrimination18:58 Linking Mortgage and Experian Data20:14 Evidence of Discrimination in Auto Lending22:48 Challenges in Passing Auto Lending Regulations24:00 The Realities of Owning and Operating a Bar30:24 Transition to Administration at Rice Business33:47 Reflections on a Diverse CareerOwl Have You Know is a production of Rice Business and is produced by University FM.Episode Quotes:How Dean James pursues scientific rigor34:50: [James Weston] I sort of view the thing that ties together all my papers as a foundational social scientist trying to measure things that are hard to measure. And so when I see things that I think have a lot of social import or a research question that I think has either a practical application or some large social question that I think needs answering, the fun for me is trying to figure out how to measure it and trying to come up with a clever way of identifying the research question in a way that's unambiguous and in a way that we can solidify and say, like, that's the answer. And I know it with as near scientific certainty as I can — you know, the existence of the Higgs boson particle.35:19: [Maya Pomroy] We can't get into that right now. Yeah. 35:33: [James Weston] But, but you know, but I'm saying, like, to treat it like a scientist.35:36: [Maya Pomroy] Yes.35:37: [James Weston] And study it like it's a real causal question. Yeah. And you attack it with the scientific method, and you attack it with the scrutiny and the scientific rigor that they use across campus.On pushing for transparency in auto lending23:20: My hope is that the Senate Banking Committee continues to take action on it, and we see more—just something similar to the Home Mortgage Disclosure Act, where auto dealers just have to report. They have a spreadsheet, and you just have to send it to the Fed the way every bank does with every mortgage application. And hopefully that transparency attenuates the discrimination the way it largely did in home mortgages. It took time. It was a 10-year process. It'll probably take that long on auto lending. And we're not the only voice in this choir. There's lots of other people now that are sort of jumping on the bandwagon.How Dean James views his new job role30:48: Moving into administration means, in my mind at least, it means I'm not working anymore. In the sense that I'm not executing the primary missions of the school, which are teaching and scholarship. And so I'm not teaching as much anymore, and I'm not doing as much scholarship anymore, which means I'd better be doing something to collect the paycheck. And the way I genuinely view it is that now I'm trying to enable the rest of my faculty to do better teaching and better scholarship. My role is as a service leader, which is how I view this job—as a tour of service, not a career pivot. I didn't take this job to then become dean someplace, to then become provost someplace, to then become Supreme Commander of University somewhere. But, like, it was someone else's turn to do this very important role, which is to coordinate all the programs, get the teaching schedules done, make sure I'm protecting junior faculty and their teaching loads, make sure I'm putting the right people into the right classes, making sure we're keeping track of it.Show Links: TranscriptThe Hidden Inequality in Auto-Lending | Rice Business WisdomGuest Profiles:James Weston | Rice University

¿Somos realmente libres o el libre albedrío es solo una ilusión? En este episodio de Por el Amor de Higgs, Javier Santaolalla @dateunvlog y Enric F. Gel @AdictosalaFilosofía se enfrentan a una de las preguntas más profundas de la humanidad: ¿tomamos nuestras propias decisiones o estamos condicionados por leyes físicas, biológicas y sociales? Desde la filosofía clásica hasta los últimos descubrimientos de la neurociencia y la física cuántica, analizamos los argumentos a favor y en contra de la libertad humana. ¿Es posible escapar del determinismo? ¿O solo creemos que elegimos libremente? ¡No olvides suscribirte, dejar tus comentarios y compartir tus propias reflexiones sobre este apasionante tema! Mail para cuestiones y reflexiones: porelamordehiggs@gmail.com Realización y edición: Ike Leal (@ikefuti)

Pep Martorell es director del Barcelona Supercomputing Center, hogar del MareNostrum 5. Sentimos una extraña mezcla de fascinación y temor por las nuevas tecnologías. La ciencia tiene un impacto en el mundo en el que vivimos y la computación del superordenador soluciona problemas que no podemos tan siquiera concebir. Escribió Eduardo Mendoza en su precioso discurso de aceptación del Premio Cervantes que “las vocaciones tempranas son árboles con muchas hojas, poco tronco y ninguna raíz”. Pep, que divulga también en su propio Substack, entró en el campo de la física fascinado por los documentales de Cosmos. Carl Sagan contagió y sigue contagiando a muchos jóvenes en busca de una vocación. Ese hombre, con su pasión por la ciencia, despertó la curiosidad de muchos y mi esperanza es que este podcast haga lo mismo.Quiero dar las gracias a la Cambra de Comerç de Barcelona por haber hecho posible este episodio. Me permitieron grabar en su fantástico ático de Diagonal y no habría podido encontrar un emplazamiento mejor para la charla con Pep. La propuesta de la Cambra es atractiva para todo tipo de perfiles relacionados con el mundo de la empresa y te animo a que explores los eventos que allí organizan. La Cambra quiere ser un punto de encuentro empresarial en la ciudad de Barcelona, facilitando conexiones inesperadas y creando oportunidades en la serendipia que se genera en esos círculos. Siempre la opcionalidad del amigo Taleb, los accidentes positivos de los que te hablo en Kapital.Así narra Stephen Fry el regalo del fuego por parte de Prometeo, en su fantástico libro Los mitos griegos revisitados: “Cuando les mostró a los hombres aquel demonio saltarín y célebre danzarín, de primeras chillaron atemorizados y recularon ante las llamas. Pero la curiosidad pronto superó al miedo y comenzaron a solazarse con aquel nuevo juguete mágico, aquella sustancia, fenómeno..., llamadlo como queráis. Supieron por Prometeo que el fuego no era su enemigo sino un poderoso aliado que, convenientemente domesticado, tenía diez mil millares de usos. Prometeo pasó de una aldea a otra enseñándoles técnicas para fabricar herramientas y armas, cocer cacerolas de arcilla, cocinar carne y hornear masas de cereales, lo que enseguida desencadenó una avalancha de ventajas que supuso la prevalencia del hombre sobre la presa animal, que no podía reaccionar a las lanzas y flechas de punta metálica. No tardó mucho Zeus en bajar la mirada desde el Olimpo y ver puntos de titilante luz naranja salpicando el paisaje a su alrededor. Al instante supo lo que había sucedido. Tampoco hizo falta que le dijesen quién era el responsable. Su ira fue arrebatada y terrible. Jamás se había presenciado una furia tan extrema, tan tumultuosa, tan apocalíptica. Ni siquiera Urano, en su mutilada agonía, había experimentado una rabia tan vengativa. Urano fue vencido por un hijo que le resultaba indiferente, pero Zeus había sido traicionado por el amigo al que más amaba. Ninguna traición podía ser más terrible.”Índice:1:21 Temor ancestral a lo desconocido.8:52 Labatut ve al científico como un poeta.19:10 Mirar en el abismo del conocimiento.27:06 Las bellísimas lecciones de Sagan.30:51 Faltan chicas en las carreras STEM.42:56 La tradición catalana de comprar tecnología en Andorra.51:35 Conferencia en Solvay en 1927.1:03:15 Los misterios del big bang.1:06:58 Hablar de Newton es como hablar de Messi.1:16:51 Un superordenador en una capilla.1:25:58 Ich probiere.1:35:06 AlphaGo.1:41:53 Nobel de Química para el plegado de proteínas.1:45:59 Kasparov contra Deep Blue.1:48:23 Destrucción mutua asegurada.1:59:39 El bosón de Higgs.2:06:31 Misterios por resolver.Apuntes:Cosmos. Carl Sagan.Cosmos. Neil deGrasse TysonUn verdor terrible. Benjamín Labatut.MANIAC. Benjamín Labatut.BTG Talks. Benjamín Labatut.Beauty, truth and... physics? Murray Gell-Mann.La utilidad de lo inútil. Nuccio Ordine.El orden del tiempo. Carlo Rovelli.Cuántica. José Ignacio Latorre.

What if company culture was the key to billion-dollar success? In this episode, Kris Krohn sits down with Bill Higgs, co-founder of Mustang Engineering, who built a thriving business in one of the toughest industries. Bill shares how he transformed a cutthroat oil industry into a culture of loyalty, teamwork, and explosive growth—even during economic downturns. Learn how strategic relationships, hustle, and an unshakable culture can set your business apart.

Today's episode is one that will stir your heart and challenge you to step into the fight for justice. I sit down with Britney Higgs, founder of Her Campaign, an organization dedicated to providing restoration and healing for survivors of human trafficking.Britney's journey is nothing short of incredible. She shares how God took her from a place of personal trauma and brokenness to a calling she never expected—standing in the gap for women who have endured the unimaginable.What started as a simple “yes” to God turned into a movement. For over three years, Britney and her family opened their home to survivors of trafficking, integrating them into a family system that provided deeper healing than any program they had ever been in. But as they walked alongside these women, they recognized a critical gap: survivors needed a stabilization phase before they could truly begin to heal.So, they pioneered an 8-week emergency stabilization program—a safe place where survivors could begin recovering body, mind, and spirit before stepping into long-term restoration. And now? Her Campaign is seeing transformation like never before. Survivors are not just healing—they're leading. Some have even stepped onto staff, walking alongside others with the same compassion and hope they once needed themselves.In this conversation, we dive into:✨ How childhood trauma led Britney to believe lies about her worth and identity✨ The moment she heard God's voice for the first time—and how it changed everything✨ Her journey from a comfortable entrepreneurial life to high-risk missions overseas✨ What she learned from survivors in Iraq and why she couldn't turn away✨ The call to establish safe homes in the U.S. and how Her Campaign was born✨ The power of family-centered healing in survivor restoration✨ Why stabilization is a missing link in survivor care across the nation✨ How God uses even the darkest places to bring His glory and redemptionAnd at the core of it all? The unwavering belief that God truly does use what the world calls foolish to confound the wise (1 Corinthians 1:27). That His heart is always for restoration, even in the midst of suffering.If you've ever wrestled with how a good God could bring beauty from unthinkable pain, this episode will root you in Romans 8:18—what we suffer now is nothing compared to the glory He will reveal to us later.Bio:Britney Higgs lives in Billings with her husband, Sammy, and their four children. Together they founded HER Campaign, a non-profit organization that provides residential programs for survivors of human trafficking. She is an advocate for freedom and passionate about cultivating a culture of community living and ecosystem of holistic care for survivors of human trafficking.Anchor Verses:Psalm 68Romans 8:18Connect with Britney:LINKTREE: https://linktr.ee/britneyhiggsIG: https://www.instagram.com/britneyhiggsHER Campaign:Website: https://hercampaign.orgHER Campaign: https://www.instagram.com/hercampaignLinktree: https://linktr.ee/hercampaignCRISIS SUPPORTIf this is an emergency, please dial 911.For Suicide prevention please call the National Suicide Prevention Lifeline at 1-800-273-8255, for free confidential, 24/7 help. Or you can reach the Crisis Text Line 24/7 by texting “START” to 741-741.Head here for a list of crisis centers around the world.REPORT TRAFFICKINGNational Human Trafficking Hotline 1-888-373-7888www.HumanTraffickingHotline.org (you may submit tip online)Polaris Project Text “BeFree” (233733)***We love hearing from you! Your reviews help build our podcast community and keep these important conversations going. If this episode inspired you, challenged you, or gave you a fresh perspective, we'd be so grateful if you'd take a moment to leave a review. Just head to Apple Podcasts or wherever you listen and share your thoughts—it's a simple way to make a big impact!***

In this episode of the Picks for Poles Podcast, Usayd Koshul is joined by Southeastern University DB Brandon Higgs to discuss his next steps as he prepares for the 2025 NFL Draft.

El Antiguo Egipto sigue siendo una de las civilizaciones más fascinantes y enigmáticas de la historia. ¿Cómo construyeron las pirámides con tanta precisión? ¿Quiénes eran realmente los faraones? ¿Qué secretos esconde la mitología egipcia? En este episodio de Por el Amor de Higgs, Javier Santaolalla @dateunvlog y Enric F. Gel @AdictosalaFilosofía junto a la egiptóloga Alejandra Izquierdo @Historiaen5minutos exploran los grandes misterios de Egipto. Analizamos los secretos de una civilización que sigue sorprendiendo a la humanidad. ¿Cómo lograron los egipcios construir monumentos tan imponentes? ¿Eran los faraones dioses en la Tierra o solo líderes políticos? ¿Qué nos dice la ciencia sobre la historia de Egipto? Prepárate para un viaje en el tiempo a la cuna de la civilización y descubre lo que la historia, la ciencia y la mitología tienen que decir sobre el enigma egipcio. ¡No olvides suscribirte, dejar tus comentarios y compartir tus propias reflexiones sobre este apasionante tema! Mail para cuestiones y reflexiones: porelamordehiggs@gmail.com https://www.instagram.com/porelamordehiggs https://www.tiktok.com/@porelamordehiggs.podcast Edición: Ike Leal @ikefuti https://www.instagram.com/ikefuti https://www.tiktok.com/@ikefuti INSTAGRAMS: https://www.instagram.com/jasantaolalla https://www.instagram.com/filoadictos TIKTOKS: https://www.tiktok.com/@jasantaolalla https://www.tiktok.com/@filoadictos_oficial ---------------------------------- #Egipto #Historia #Ciencia #Filosofia #Religion #PorElAmorDeHiggs

Join us for week 3 of our current series called Peace According To... Each week, we will look at different scriptures in the Bible regarding peace. This week, we look at Psalm 4.

Join us for week 2 of our current series called Peace According To... Each week, we will look at different scriptures in the Bible regarding peace. This week, we hear from Paul and look at Colossians 3:15.

Merriam-Webster's Word of the Day for March 11, 2025 is: quark • KWORK • noun Quark is a word used in physics to refer to any one of several types of very small particles that make up matter. // Quarks, which combine together to form protons and neutrons, come in six types, or flavors: up, down, charm, strange, top, and bottom. See the entry > Examples: “One quantum field is special because its default value can change. Called the Higgs field, it controls the mass of many fundamental particles, like electrons and quarks. Unlike every other quantum field physicists have discovered, the Higgs field has a default value above zero. Dialing the Higgs field value up or down would increase or decrease the mass of electrons and other particles. If the setting of the Higgs field were zero, those particles would be massless.” — Matt Von Hippel, Wired, 19 Aug. 2024 Did you know? If you were a physics major, chances are that James Joyce didn't make it onto your syllabus. While literature majors are likely more familiar with his work, Joyce has a surprising tie to physics. In the early 1960s, American physicist Murray Gell-Man came up with the word quork, which he used to refer to his concept of an elementary particle smaller than a proton or neutron (by his own account he was in the habit of using names like “squeak” and “squork” for peculiar objects). He later settled on the spelling quark after reading a line from James Joyce's Finnegans Wake: “Three quarks for Muster Mark! / Sure he has not got much of a bark / And sure any he has it's all beside the mark.” The name stuck and has been used by physicists ever since.

Nick Higgs, widely known on social media as Nick Higgs The Singer, is a multifaceted professional in the music industry. As a dedicated singer, voice teacher, and dynamic content creator, he has cultivated a substantial online presence, engaging over 500 thousand followers across various platforms. With a background that includes formal musical education from the University of Toronto, and experience performing in groups such as the Tafelmusik Chamber Choir, Nick combines classical training with a modern approach to music. He displays a strong passion for digital media, and actively motivates fellow musicians to embrace the digital world, emphasizing the importance of establishing a meaningful digital footprint. He shares vocal performances, educational content, and musical analysis to his large online audience. You can find him on social media at the username @nickhiggsthesinger.

Before founding An Eventful Life, Debbie Higgs had Already spent years immersed in the equestrian world, capturing the sport's most exhilarating moments and covering prestigious events worldwide. Now with a wealth of experience behind the lens and the mic, she continues to bring the action to life for eventing fans across the globe.With a passion for storytelling and a keen eye for cross-country courses, Debbie has built a career showcasing the sports most thrilling moments while navigating the ever-evolving world of Equestrian media. Capturing the heart-stopping action of eventing from behind the lens, covering everything from grassroots competitions to the Olympic Games, Debbie has seen it all!IN THIS EPISODE:If you could film at one event every day for the rest of your life, which would it be? Debbie shares her top picks - from the stunning Scottish Highlands at Blair Castle to the legacy of the Sydney Olympic venue.What happens when a journalist sings to Michael Jung? Debbie spills the details on one of the funniest behind-the-scenes moments in eventing media!From security mishaps at Paris 2024 to a bullet landing in the press tent at Rio, Debbie recounts the craziest moments she's witnessed whilst covering  major events.What's it like being part of the 'travelling circus' of equestrian media? Debbie gives us an inside look at the fast-paced, globe-trotting life of covering major competitions.How do you get the perfect cross-country shot? Debbie shares what it takes to capture the action and emotion of eventing on camera.What's next for An Eventful Life? Debbie gives us an inside look at the future of eventing media and what's on the horizon.All this and so much more in this episode of THE EQUESTRIAN EXPERIENCE.

La muerte es lo único seguro en la vida… pero ¿qué significa realmente? ¿Es el fin absoluto o hay algo más? En este episodio de Por el Amor de Higgs, Javier Santaolalla @dateunvlog y Enric F. Gel @AdictosalaFilosofía exploran cómo la filosofía, la religión y la ciencia han intentado responder a la pregunta que todos nos hacemos: ¿Qué pasa cuando morimos? Desde los antiguos filósofos griegos hasta las creencias religiosas sobre el alma. Analizamos cómo ha cambiado nuestra visión de la muerte y qué podemos (o no) saber al respecto. ¡No olvides suscribirte, dejar tus comentarios y compartir tus propias reflexiones sobre este apasionante tema! Mail para cuestiones y reflexiones: porelamordehiggs@gmail.com Edición: Ike Leal (@ikefuti)

3 big ideas discussed in this episode: BIG IDEA #1: Find Your Niche BIG IDEA #2: Get an Accountability Partner BIG IDEA #3: Leverage Groups Get the show notes for this episode here: https://AskJeremyJones.com/podcast

The Zone with Jason Anderson, Sterling Holmes & Producer Dylan Michaels rolls on as Sterling talks to Harry Higgs about the upcoming Advent Health Championship and his rise to golf’s highest stage. Then we listen to some more sound from Andy Reid and Brett Veach at the combine today.See omnystudio.com/listener for privacy information.

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 7, we are diving into the story of Jael and the tent peg found in Judges.

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 5, we are diving into the Apostle Paul.

In this episode of The Faces of Business, Ron Higgs, Founder and Principal at Wolf Management Solutions, LLC, will share invaluable insights on Keys to Building a Team for a Smooth Exit. Ron discusses how creating a strategic, capable team ensures a successful business transition and builds long-term value. Ron is an accomplished executive coach and strategic business advisor with over 20 years of leadership experience across operations, engineering management, and program management. As a Navy veteran and former aerospace engineer, Ron honed exceptional leadership and team-building skills, which he now brings to help businesses achieve operational excellence and scale effectively. Check out the Blog post here: Keys to Building a Leadership Team for a Smooth Exit   Thanks for taking the time to listen today.   Find Damon Pistulka on LinkedIn talking about life & building businesses you can sell or succeed.    On Twitter as @dpistulka with inspiration and sharing thoughts.    Find out more about Damon when he's not working.  @damonpistulka on Instagram, or Damon Pistulka on Facebook.      More information on building businesses you can sell or succeed and the Exit Your Way method on our website   View our blog page for this episode here.   Email us for more information info@exityourway.com

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 6 , we are diving into the story of Ehud and Eglon in Judges.

Tiny microbes have a big impact on wine quality. Aria Hahn, CEO and co-founder of Koonkie, Inc., discusses the exciting work her bioinformatics organization is doing in the field of metagenomics. Hahn explains the differences between genetics, genomics, and metagenomics. She shares insights from a project studying yeast populations in British Columbia's Okanagan region, revealing the diversity and distinct clades found on wine grapes. The conversation also covers the broader applications of bioinformatics in agriculture, including regenerative farming, soil health, and potential bioprotectants against wine spoilage. Hahn underscores the impact of microbiome management on wine terroir and the potential of bioinformatics in understanding and improving winemaking processes. Resources:         201: Balance Hot Climate, High Sugar Wine with Green Grape Juice aka Verjus 243: Microbial Communities in the Grapevine 251: Vine SAP Analysis to Optimize Nutrition Aria Hahn – Google Scholar Aria Hahn – LinkedIn Koonkie Make Better Wines with Bioinformatics The Microcosmos - Discover the World of Genomics Apple App Whole genome sequencing of Canadian Saccharomyces cerevisiae strains isolated from spontaneous wine fermentations reveals a new Pacific West Coast Wine clade Vineyard Team Programs: Juan Nevarez Memorial Scholarship - Donate SIP Certified – Show your care for the people and planet   Sustainable Ag Expo – The premiere winegrowing event of the year Vineyard Team – Become a Member Get More Subscribe wherever you listen so you never miss an episode on the latest science and research with the Sustainable Winegrowing Podcast. Since 1994, Vineyard Team has been your resource for workshops and field demonstrations, research, and events dedicated to the stewardship of our natural resources. Learn more at www.vineyardteam.org.   Transcript [00:00:00] Beth Vukmanic: Tiny microbes have a big impact on wine quality. [00:00:09] Welcome to Sustainable Wine Growing with Vineyard Team, where we bring you the latest in science and research for the wine industry. I am Beth Vukmanic, Executive Director. [00:00:19] In today's podcast, Craig McMillan, Critical Resource Manager at Niner Wine Estates, with longtime SIP certified vineyard and the first ever SIP certified winery, speaks with Aria Hahn, CEO and co founder of Koonkie Inc. [00:00:35] She discusses the exciting work her bioinformatics organization is doing in the field of metagenomics. Hahn explains the differences between genetics, genomics, and metagenomics. [00:00:47] She shares insights from a project studying yeast populations in one of British Columbia's wine growing regions, revealing the diversity and distinct clades found on wine grapes. [00:00:58] The conversation also covers the broader applications. bioinformatics in agriculture, including regenerative farming, soil health, and potential bioprotectants against wine spoilage. [00:01:09] Hahn underscores the impact of microbiome management on wine terroir and the potential for bioinformatics in understanding and improving the winemaking process. [00:01:19] We know your customers are looking for sustainable wines. In a recent review of 30 studies, Customers reported a higher preference for eco label and social responsibility labels compared with nutrition labels. Achieving SIP certified gives you third party verification that your vineyard winery or wine has adopted and implemented stringent sustainable standards. Apply today at SIP certified. org. [00:01:46] Now let's listen [00:01:50] Craig Macmillan: Our guest today is Aria Hahn. She is the CEO and co founder of Koonkie, Inc., a bioinformatics organization, business, doing all kinds of exciting stuff. Thanks for being on the podcast, Aria. [00:02:02] Aria Hahn: Yeah, so excited to be here. Thanks for [00:02:04] Craig Macmillan: We're going to get into the thick of it But we were attracted to some work that you folks and your colleagues have done with bioinformatics and yeast, wild yeast. But I wanted to drop back. A little bit first to kind of give some context. All of this kind of comes under the umbrella of metagenomics, correct? [00:02:21] Aria Hahn: Yeah, absolutely. [00:02:22] Craig Macmillan: and what is metagenomics? [00:02:24] Aria Hahn: I'm going to take further step back and talk about genomics um, maybe the distinction between genomics and genetics. [00:02:32] So genetics is something I think most people kind of understand. They have this intuitive sense of it. um, that make up ourselves and all living creatures. But it actually turns out that in most organisms, and not bacteria, and we'll get there in a Most of your DNA is not in genes. It's in between genes. And so genomics is the study of genes and all of the things that are in between genes. So that's kind of the distinction between genetics and genomics. And then metagenomics is when we do that at the community level. [00:03:02] so you could do metagenomics of humans, but metagenomics refers to populations of bacteria, uh, microbes, archaea, viruses, things that you cannot see and I'll say interact with directly. [00:03:17] Craig Macmillan: And then bioinformatics is a subset or is a technique, is that correct? [00:03:23] Aria Hahn: Yeah, it's a technique, you know, it used to be even 10, 15 years ago that everyone kind of did their own bioinformatics. And so really what that means is when we sequence DNA or read that DNA, so it's only four letters, ATCs and Gs, we extract the DNA the sample is, could be the surface of grapes, uh, a human, anything. [00:03:42] Um, Then we put it on a sequencer. There's a bunch of different sequencing technologies right now. Um, But you end up with these like very gross files that aren't openable on regular computers and they're literally just ATCs and Gs. And so bioinformatics is the cross section of high performance computing and biology. And so we develop algorithms and processes and pipelines to really take those gross huge files of ATCs and Gs and make them human readable. make them interesting, figure out, you know, what are the genes that are there? Who is there? What are they doing? And who's doing what? [00:04:19] Craig Macmillan: Okay, and I think that's the important part here is you would take a sample from the environment. We'll talk about this one more in a second, but there are particular sequences that may be associated with a certain type of microbe or even a particular genus or particular species of microbe that can be detected. [00:04:39] Aria Hahn: Yes, absolutely. [00:04:40] So a genome is all of the DNA that makes up that organism. So you and I have distinct genomes, but of course, our genomes are going to be pretty similar to each other compared to a human genome, to a fish, to a plant, to a [00:04:55] Craig Macmillan: why the focus on microbes? [00:04:57] Aria Hahn: Yeah, that's a great question. It depends how philosophical You want to get You know, people are generally [00:05:02] familiar with the concept of like the Higgs boson particle. It's like the God particle that makes up everything and that's great and the physicists are gonna come for me. But when we think about our planet Earth, I always say like If there is a god particle on this planet that is alive and that we interact with, like, it's a microbe. [00:05:21] This is their planet. They were here long before us and they will surely be here long after us. So we think about microbes in terms of they are the destroyers of higher level populations. They keep us healthy. They make us I'm going to say it's a great example, but it wasn't a great thing. [00:05:40] So caveat that. But COVID was a great example about how this is not our planet where we had an of a virus in one location in a very particular place in the world. And all of a sudden it was across the planet. We are vectors for them. [00:05:58] You know, looking at those maps and showing the spread and how quickly it happened, I like to use that often in visual presentations to say, if you don't believe me, like, look at this. It's spread through us. [00:06:10] Craig Macmillan: Right. And I think also this gets to some other things we might talk about later on, but there are communities of microbes that are associated with certain macroorganisms. [00:06:23] Aria Hahn: uh, so are, they're everywhere, they're on your um, there's lots of research in the cosmetic industry that's looking at that. There was this crazy CEO years ago where he was I'm gonna slather this microbial laden cream on my skin and then I'm never gonna shower again and I'm not gonna smell. Not necessarily like my cup of tea, I love a good hot shower. But, you know, it can be there. The soil is the microbial diverse environment on the planet. , But your gut, like you, you as a human being, can't actually digest your food without those microbes. You can't get those vitamins and nutrients that you need without that community in your stomach. [00:07:03] Plants work the same We say charismatic macrofauna, eagles, whales, things that are very Um, They, they don't to, you the seaweed and the weeds and the grass and kind of everything in between. it's All supported by the microbiome, by these microbial communities. [00:07:20] Craig Macmillan: so let's talk about one microbiome in particular, and that would be populations of yeast that we find on wine grapes. [00:07:29] Aria Hahn: Yeah, yeah. So we've looked at yeast and bacteria and they're both cool. [00:07:34] Craig Macmillan: That is super cool. And so this one particular project where you looked at yeast on wine grapes in British Columbia Tell us a little bit about that project [00:07:41] Aria Hahn: there's, So I live in I'm, I'm right in the thick of, you know, BC wine country, which is a fantastic place to live, we were fortunate enough to work with the Wine Research Institute out of the University of British Columbia, Vivian Mease Day's group. them and They do very, very cool work, but they were trying to look at the yeast populations in wineries across the Okanagan region. [00:08:02] We know that the history of lots of commercial. Yeasts are actually from oak trees in Europe. So that's very cool. And what we wanted to see is how are the yeasts that are being used to produce wine in the Okanagan region distinct and similar to commercial yeasts and yeasts that have been characterized from across and so We did just that and we were actually able to sequence a whole bunch of yeast. And so, again, that's like reading the genome effectively there. so we found four distinct clades, um, in the Okanagan region. And a clade is they're related groups, and so it's not like you and you're a twin where you might have an identical, uh, genome to a twin. [00:08:50] It's more like you and your cousins and second cousins and second cousins twice removed and, you're, you're kind of vaguely related to each other. You kind of cluster over here, but you're not necessarily super We've kind of found four clades that the 75 yeast strains that we studied in that particular piece of work Really related to, then we looked at like what is different in their genomes. [00:09:12] So they're all the same species. That's the first thing to, to think about here. So just like you and I are the same species, they're all the same species, but just like you and I, we have different areas of, of specialties. Some people podcasters. Some people are, artists and scientists and, um, kind of everything in between. [00:09:33] And we need everybody. So, we're all the same species, but we have different specialties. And the yeasts work very similarly to that. [00:09:40] Craig Macmillan: all right, so this is interesting to me so You go out and you you said when you looked at 75 species of yeast or different types of yeast Those are ones that you, you found. It wasn't like you went in and said, I want to test for each of these 75. You got information, you got data in and said, Oh, look, here's 75 different types of [00:10:01] organism. Yes, that's a, that's a great Um, so, we And we uh, the ferment or the, the yeast skins and we extract the DNA and then we get rid of the great DNA, which could probably also be really cool, but we didn't look at it in this case. And kind of threw that into the and then said, okay, we're just going to focus on the Saccharomyces cerevisiae Latin term for a very common yeast strain, um, used in wine. And we said, we're going to look for it. [00:10:30] Aria Hahn: Then we found actually hundreds and . And then, um, and I didn't do this work, I don't do a lot of lab work myself, so, uh, this part is kind of the edge of my knowledge. But there is some ways to kind of do microsatellite clustering. And so you look, and you look for tiny differences in the genome, and you say, okay, maybe we found 500, but we actually want to look at ones that are distinct from one another. So we don't want to randomly pick 75, we want to pick 75. strains of this yeast that are different from one another. [00:11:01] And so you could use some lab techniques to make that happen. And then you take those hundreds and we say, these are the 75 that we know are different. We're going to dive deep into those 75 so that we can kind of get this breadth of genetic diversity from the region. [00:11:18] Craig Macmillan: And that was something I was thinking about. You mentioned you took samples from either fermenting wine or recently fermented wine or from skin material. How exactly is this collected so that you know that you're getting just [00:11:30] what you want? [00:11:31] Aria Hahn: Yeah. Painfully is the answer. So like when you do soil sampling, it's actually really And we tell people all the time sampling for yeast or microbes is not that complicated. I say every single time we talk to a client, I'm like, look, wash your hands with ethanol, you know, hand sanitizer, essentially between rinse your tools. And mainly you can't mess this up as long as you don't spit in the bag or bleed in the And I say this every time, and I will say one out of every few hundred samples is full of blood. Hands down like you always think we always the that and then hands down. We're like, this is full of And I think it's just like a matter of working in the field like people nick themselves They don't really realize that but really that kind of thing is really easy [00:12:15] When it comes to sampling a ferment that can also be fairly easy. [00:12:19] You have a lot of it You can kind and put it in a jar, but I will Um, Jay Marknack, who's done a lot of this work and developed a lot of these methods, he actually developed this method that is painstaking. Um, But you have like, he's got this method where he takes the grapes really carefully without touching them off of the and then washes just like very carefully with these like rinse solutions to really just get the microbes and yeast that are on that surface without touching it, without touching other surfaces. It's really just what was there in the field. And rinse all of that off. And you can imagine that's not that fun of a Um, And, and, and so, and it wasn't like he did it on his first try either. So he's now developed that we're copying and using, thank goodness. Uh, But it can be like that kind of painful where it's like washing individual grapes, collecting that rinse water, and then filtering that rinse water, like onto a physical filter, then extracting the DNA from that filter. [00:13:18] It's not fast. [00:13:19] Craig Macmillan: Nope, that's what I wanted to know. I've collected a lot of soil samples in my life for looking at soil microbiome. And you know, technique is everything. You know, contamination will mess you up pretty badly. [00:13:29] Aria Hahn: We had this one study I felt so bad, but they had collected these samples. They sent us the samples and we get the data back and it's, they're soil, they should be teeming with life, right? [00:13:38] And there's like one species basically in this thing, like there's a handful, but like one is dominating. So we go to them and we're like, what is going on here? And they're like, well, I don't see how that could have happened. , we've been storing these in a dark closet for a year. And we're like, that's why. You are studying bottle effects right here. And they're like, oh, we thought it'd be fine because it was dark and cool. And we're like, yeah, but it's not open to the air, and it doesn't have the plants and animals and bugs. You grew one guy. [00:14:07] Craig Macmillan: Yeah. We've been talking about bacteria, or the yeast. Are there other types of organisms, microorganisms, that you can use this technique with? [00:14:14] Aria Hahn: Totally. So you can use this technique on basically anything that's alive. So you could target viruses, uh, not something we've done on wineries, but could absolutely do it. You can target, , archaea, which are very similar to bacteria in that there are a single cell. But they are similar to eukaryotes. [00:14:32] So things that are bigger, um, like us, like mammals, like fish, Uh, but they are kind of small and invisible, , to the naked eye like bacteria. So those, we can, we can do that all the way up to, any animal that we can see, feel, touch, , and kind of anything in between. So it's a really powerful technique. As long as it has DNA, we can make this work. [00:14:53] Craig Macmillan: So you found these 75 types? of yeast organisms, but they fell into groups, they fell into clades. And I thought that was one of the most interesting things about this. Can you tell us a little bit about the natural history of behind these clades and kind of what that means? [00:15:09] Aria Hahn: We found these 75 different strains and they did group into four clades. So four kind of groups of more or less related organisms. So you can think of them as like clustering based on similarity. [00:15:22] The first one was one that is well known and well studied. So that's wine and European. And so those strains are more similar to these that we see in wines out of Europe and commercial strains. [00:15:35] And then the second clade we saw was the trans pacific oak. So a lot of wine yeast are very closely related to yeast that are found on oak trees. And so actually think that, , the original, , European wine yeast strains from, you know, the 1800s are from Mediterranean oak trees. And so it's not uncommon that we see these strains related to oak. [00:15:59] So that was the trans pacific oak. Then we see another group or clade that we called beer one mixed origin. And so we saw similarities to known previously studied yeast strains that are related to beer, sake, so other kind of fermented drinks. also kind of expected. [00:16:18] And then what was really exciting is that we found a new clade that we've designated the Pacific West Coast wine clade. it's always neat when you get to discover something new, of course. And so it has high nucleotide diversity. And so what that means is that even within this clade we do see a lot of genetic diversity kind of in there. [00:16:38] And what we do know is that that whole clade shares a lot of characteristics with wild North American oak strains, but, and this is kind of where like it all kind of comes full circle, but we also see that it has gene flow from the wine European and Ecuadorian clades. It can mean a couple of things. So it could mean that There is just so much selective pressure when you're, when you're trying to make good wine that these genes that are found in European wine strains, commercial wine strains, they're present in Saccharomyces cerevisiae in general, but then when we try to make good wine, we select for strains that have these, genes, , that we know produce good wine, because they produce good wine everywhere. [00:17:27] And so it could just be this process of natural selection. It also could be that most wineries , are not purists. It's not that. never in their history have other wine strains visited their their vineyards. They might have tried a commercial strain. They have wine from others, you know, people track things in, animals track things in. And so it could just be that there is this gene flow, quite literally from, from Europe, from these wine strains that just kind of comes into our population here in the Pacific West Coast. [00:18:00] And so there's kind of these, these two ways that we could have got these things, We do have some evidence to suggest that they were actually transferred in. [00:18:07] So it's called horizontal gene transfer. And my go to example on how horizontal gene transfer works is always , The Matrix, like the movie with Keanu Reeves. But what I've also learned is that if you talk to people that are like younger than me, they don't know that movie anymore, so this only lands with like a certain age of [00:18:23] Craig Macmillan: Right, I know, I know, [00:18:24] Aria Hahn: You know The Matrix where they like plug in and then they have all these new skills? [00:18:28] Bacteria can kind of do that, where you can just take genes from, , a relative, has to be like kind of closely related, and we take them and then we just put it into their genome, and in many cases, not all, but many, they're able to just kind of start making use of those genes right away. [00:18:43] And so that's horizontal gene transfer, which is pretty cool, because for us, the second that sperm hits the egg, that's it. That's all your genes. You're not getting more. You're not losing more. Like you're, you're set. But bacteria are more fluid. [00:18:57] So there is this cool thing called the wine circle, and it's a cluster of five genes that are associated with making commercial wine. [00:19:05] And we do think because we see this wine circle and these particular five genes in so many wine strains, and because of their location and a whole bunch of other kind of genomic characteristics of them, Um, we think that they are horizontally transferred. And so we do see this wine circle of these five genes in the majority of this new clade of British Columbia strains. [00:19:33] Craig Macmillan: So just talking about moving things around the world, you said like people have things on their bodies and whatnot. I, I was fascinated by the Ecuadorian group. And is that literally like it was growing on plants in Ecuador, kind of native to that area that is found its way up the West coast of North America. [00:19:53] Aria Hahn: that's really what we thought happened. I know it is amazing, right? Like does the amount and transfer and you know how you go through the airport and they're like, you and It's like the end of the world. It's like I get it because we don't want to like do that on purpose, but also the ecuadorian yeast like it's coming up here [00:20:12] Craig Macmillan: right, right. Exactly. [00:20:14] So what I think is of interest to winemakers, and also has potential beyond that that I'll ask you about winemakers are looking for increased complexity in their wines, and they're also looking for a sense of place. And I'm really happy to hear more and more people talking about terroir, not just in terms of rocks, but in terms of the whole picture. [00:20:33] The soil microbiome, the practices that are done, as well as light and climate and all those kinds of things. What are some of the things about what you found that indicate or that suggest a uniqueness to that Okanagan area that may make it stand out as different than other locations? How does this translate into sense of place? [00:20:54] Aria Hahn: That's a fantastic question. I'm going to give two answers first on the east side. We see that many of that nucleate. don't have all five of those wine circle genes. And so we see a lot of British Columbian strains have that, but there's this whole clade of these natural yeast used in wine that don't have all five of those. [00:21:17] So then you just have different genes to work with. And since you have different genes to work with, it's not just those genes, but it's all of the genes, and it's the rate that those specific strains are able to break things down. [00:21:28] You do get this added complexity when you're not using a standard commercial yeast. You just have this bigger variety of genes to choose from, and That's going to make the flavors more specific, and different. [00:21:44] It also introduces a certain, the disadvantage of using these is that, you know, they are gonna vary year to year, month to month. Uh, Potentially, and, and so you might get really, really amazing results one year and not the next year, and understanding why, why that might be is a whole exercise in and of itself, probably doable, but it's really exciting to think that these yeasts that are there naturally , they just have that genetic diversity and they want to live in these diverse communities, and so you are going to get that difference and terroir. [00:22:16] The other piece that was really exciting and was a different piece of work, but very similar groups and very similar, , samples, was looking at the microbiome, so the bacteria on the grapes. And we kind of found two things, and so there is some literature that shows if you look at a single farm, a single vineyard, and you look at different red varietals of grapes, you see actually a fairly similar microbiome signature on all of the different varietals. [00:22:46] Okay, but if we look at three distinct vineyards that are all within , one kilometer radius of one another. So they're very close. They have the same rock, to your point. They have the same weather. They have the same climate chaos happening, [00:23:01] but they're managed differently. We actually see very, very distinct signatures on all three that persists year after year. So we looked at two years, , this was again, Jay Martinek's work, , and we see that each one of those, even though it's the same varietal of grape, it is more similar to itself, year over year, than among the three farms. and and that's very interesting because what that suggests is Exactly what you're saying. [00:23:29] It's not the rock. It's not the climate that's driving the microbiome there. It's actually the practices of that vineyard that are changing that. And to me, that's so powerful, because what that means is that there's so much of that craft and art in the management of the vineyard that's then going to go and affect the terroir. , I know that's not the yeast answer, but that's the bacteria answer, and it's like, the power's in your hands. [00:23:54] Craig Macmillan: I'm on the Central Coast of California, and we've had some very hot vintages in this last , 2024 season. We had, and it was 2022 as well, we had these really hot stretches of over 100 Fahrenheit. Not very friendly to yeast in general. [00:24:09] Probably friendly to some, but not to others. And I had conversations with winemakers along the lines of like, could you even do a natural fermentation this year, a native fermentation? Are they there anymore? Or have they been selected against due to the heat? And I now have a total reset of the microbiome, the microflora in my world. this is the kind of thing that bioinformatics would be able to determine. [00:24:34] Aria Hahn: yeah, for sure. So we love that. We love when we get the baseline. We're like, show us your year that you were like, this is my typical year. This is my regular year. We'll live for that because as soon as you have the baseline, then we can go and answer those questions. So we can say, okay, great. We know what your baseline is when you typical year. [00:24:52] Now you have this heat wave that comes in. , Let's go and look. Let's go see who's survived. And I know I anthropomorphize all of these things a ton, but it really is, like, who's there, right? , is it the same bug, but very decreased? Are we getting different E strains coming in? are we seeing less overall diversity? [00:25:13] Do we see the same diversity, but Their population is a quarter of the size, and how does that affect the dynamics? Like, what do we see? And bioinformatics can absolutely absolutely answer these questions. And that can be really powerful. [00:25:26] Craig Macmillan: In my research I didn't pick up on this Can bioinformatics put a quantity on things? Can you quantify the relative size of these different populations? [00:25:34] Aria Hahn: We can, yes. So, you have to use some kind of special techniques. There's a couple of main ways we do them. One is called qPCR, so quantitative PCR. And so we literally take the DNA and we can count the copies of it in a very quantitative way. That's straightforward, pretty inexpensive. [00:25:52] Another way we can do it is a little bit more sophisticated, , but you don't have to know what you're looking for. So with quantitative PCR, we have to know, like, we want to go count saccharomyces cerevisiae. But if we don't know all of the microbes that are there, all of these that are there, then we can't go and target it with qPCR. So then what we have to do is use a spiken. the concept is pretty simple. You put a known quantity of a piece of DNA that we would not expect to appear in nature. And then when we sequence it, we know how many we got back. So if we know we put in a hundred copies of it and we get 200 copies back, now we have a pretty good idea of like, everything there was, sequenced twice or if we get 50 copies back, we're like, okay, well, however many we have, we're going to double that and we have a good idea and we do do this in like a little bit more sophisticated way where we put in like a whole bunch at different quantities so we can double check our math and make sure that it's all good. [00:26:49] But that's the concept is with a spike in so you can do it quantitatively. [00:26:53] Craig Macmillan: Talking about all the things that are out there, there's a lot of interest right now in bioprotectants for fermentation, where you introduce non fermentative yeast, and they kind of take up the ecological niche against foliage organisms, and then you can add a Cerevisiae strain to do that, to do your fermentation. [00:27:10] Would you be able to pick up those other genus, of yeast in a bioinformatic way and gives us a sense of what else is out there. [00:27:18] Aria Hahn: Yeah, for sure. So we sequence the whole community and then we kind of in a. Like a puzzle. I'm going to put together the individual genomes of everyone who's there. And so we can look at not just the targets, but the unknowns as well. And so often, especially in soils, what we get is sometimes up to 80 percent of the genomes that we're able to recover from that sample are totally novel. [00:27:43] So they're new to science. It's really exciting. and we hate it. We love it and we hate it. So, we love it because it's really fun. You, you discover these new species of bacteria, of yeast, or these new strains, and, and you get to name them. You don't have to name them after yourself anymore, you have to name them about the place that they're there. Which is a totally logical thing. But, would have been fun. , [00:28:06] So we get to name these things, it's really exciting. [00:28:09] But it also means it's so much work. Because now you have this genome that's so new. And so now you're trying to figure out. What are all the genes? Do we know the genes it has, but just not quite the way that they're arranged? Do we not know what many of these genes do? And if we don't know what these genes do, like what kind of uncertainty and questions does that bring up? And so it can be really exciting, that discovery phase, and also quite overwhelming, honestly. [00:28:36] Craig Macmillan: what other applications might there be for bioinformatics in wineries or in vineyards? [00:28:41] Aria Hahn: Yeah, that's fantastic. So definitely monitoring. You know, regenerative farming is a really big thing right now. how can we introduce additional species, cover crops, , you know, planting additional or different plants in between. Like, what can we do to really increase the soil health, sequester carbon, the biodiversity of the soil, of the land, and how does that affect it? So we can monitor all those things with environmental DNA or eDNA. [00:29:09] One thing that we've been thinking about a lot is this concept of smoke taint, which I think has kind of affected the whole west coast of North America. [00:29:18] Are there microbial treatments that can kind of mitigate smoke taint, , can we feed bacteria, the bacteria that we know [00:29:29] can kind of break down those volatile phenols that cause the smoke taint. Get them to kind of break that down first before we make the wine. Like we're kind of looking at applications like that. [00:29:40] Obviously those are, I would say further out in terms of technological development biodiversity, which we can absolutely go and do today. , but there's interest in that smoke taint. Application, and we're really interested in that. [00:29:52] Then there's also kind of everything in between. So can we the harvest? Can we increase the quality of the grape? Can we help with years that are dry? Can we help with years that are wet or cold or hot? as we, kind of committed to a certain number of effects of climate change, we have to start thinking creatively. [00:30:14] I was on this call with an unrelated company. They wanted to do similar things but in the mining space, in the reclamation space. And I don't know how it happened, but I was on this call with this man. It was his last day before it was dark where he was. He's in Quebec. He's three hours ahead. [00:30:29] , You know, it was winter. So it's very, the mood was very, like, dark and somber, and this was his final call of his final day of work. And he was so hopeful about microbes, and he spent his career working with them. And just before he signed off the call, he says, I hope microbes save us all. [00:30:50] And then he kills the call. And, and, for, the next few years, I titled every single talk I did, Microbes may save us all because I just, the weight of that conversation was so big and I know that's not what we're talking about here in terms of [00:31:08] smoke taint, but I do think, you know, to bring us full circle to this like omnipresent godlike presence of microbes that there's something to that idea in that I think that they have this potential to save us from ourselves. If we can learn more, [00:31:25] Craig Macmillan: I think what we're talking about is bioremediation and the potential there. And bioremediation would work by identifying an organism that's going to play a certain role and then actually introducing it into the environment. For instance, like introducing it to wine that may have smoke taint, for instance. [00:31:40] Aria Hahn: , so there's a three main approaches to that. [00:31:42] So the first is exactly what we're talking about. You introduce a micro that we know and you, and you put it in there. The main challenge of that is this, this word we call engraftment. We actually steal that word from organ transplants. So, when you put in a new heart, not that I know anything about heart transplants, but when you put in a new heart, you have to engraft it. [00:32:01] And so people need to be on immunosuppressants, is my understanding, to make that heart transplant like stick in their body, have their body accept it. Kind of the same challenge when you introduce a microbe into an open, wild environment where you need that new species to engraft in that community. If you can't do that, you just have to keep adding it. [00:32:21] You have to keep adding it, keep adding it, it's time consuming, it's expensive, all of these things. So engraffing is still a challenge in that field. But that is one way. [00:32:29] The second way is to bioengineer. And so the concept here is that you take species or strains that are naturally occurring, so they do well in that environment, and you change something in their genetics and then reintroduce that. It does get around the concept of, [00:32:50] of engraftment in theory. The major issue with it is, there's not a lot of people or companies that feel ready, I think, to take a biologically engineered synthetic genome and introduce it into the environment en masse. We just don't understand the risks of it, or, or not, we don't know, but I think that's the point, is that we don't know, and so people are a little bit like, Maybe we're not quite there yet. [00:33:19] And then the third way is to say, I'm going to look at who's already there. And I'm going to understand what they like to eat and what their competitors like to eat and I'm going to try to starve their competitors [00:33:31] and really feed the ones who have the capacity to degrade those volatile phenols. I'm going to like try to get their population to do super well and thrive. and and try to kind of starve out and make the populations that can't do the job that I want lesser and less prevalent in the community. [00:33:51] And that approach I think is kind of one of my favorites where we understand and then we put some selective pressures. So this could be adding more nitrogen, adding different carbon sources. [00:34:01] It could be watering less to create a more aerobic environment. It could be you know, kind of drowning them to create an anaerobic environment. It's kind of those bigger controls that we have working with the microbes that are already there. [00:34:17] Craig Macmillan: Yeah, in the same way that we're not afraid to play with plant communities in agricultural systems, with cover cropping or intercropping or anything like that, same kind of idea, where maybe I plant something that I think will out compete a weed. [00:34:28] Same kind of idea. And we're pretty comfortable with that. [00:34:32] And also things will have a way of finding their stasis, finding their, their It's just getting it kind of pushed in the right direction. I think that he's super, super cool. [00:34:44] A lot of interest and work in the soil microbiome in terms of soil health. We mentioned regenerative agriculture. I have put my toe in that, in, in my professional world extremely difficult, extremely confusing, lots of holes you know, and, and trying to find markers or metrics has been. challenging for instance, I was trying to figure out how healthy some soils were. It, healthy in quotes, and I wanted to do analysis of respiration. And this very good soil ecologist said, well, that tells you how many folks are in the room, but it doesn't tell you what they're doing or who they are. [00:35:21] And I was like, that's a really good Point I could have a lot of respiration from organisms. I don't want and I wouldn't know what was who and who was what? What world can bioinformatics play in that [00:35:33] Aria Hahn: , that's a great question. So I would say it's the opposite in general, without the spike ins and kind of specific things, what? we can tell pretty inexpensively, 50 to 100 a sample, is basically who's in the room and in what relative abundance. So it is come down a lot in price. It doesn't tell us a lot about their genetic capability. [00:35:55] So if we know them because they've been previously studied, then we can say like, oh, yeah, these guys are known to do X, Y, and Z. [00:36:02] If we don't know them, for that kind of price point in those methods, we're kind of just like, yeah, we know their names. But that's it. [00:36:08] Then we can do kind of a deeper dive, , to a different type of sequencing called whole genome sequencing. And you get the whole genome. And so there we can actually say not only who they are, but what they're doing. Or what they have the ability to do. And so that's where the limit of DNA is, is that it can tell us the potential. They can potentially do this, but it doesn't actually tell us if they're choosing to do that, so to speak. [00:36:33] There are other techniques that are very related. Metatranscriptomics, it's looking at the RNA, and you could do metabolomics. So you can actually look at the metabolites that they're producing, and then it tells you what they actually did. But we often can start at that base layer of DNA. and build up. So those questions we can answer. [00:36:51] And I think you're right about there are a lot of holes and it's confusing and it's complex. And we say this to clients all the time, like, if you know way to solve a problem, do that. Biology is messy. [00:37:03] But if you don't, like let's look at biology and let's enjoy the mess , there's a lot of beauty in that mess. And that's one of the things we've actually loved about interacting with wineries they are incredibly scientifically minded folks. They're data driven, the amount of innovation and technology they're using. never fails to impress, but you also get that love of the art and the craft from them. We love that. We see art and science as like in a circular spectrum. And so we love when, our clients in the, in the wine start talking to us about kind of their secret sauce and the things that they've tried and how, and they always get a little bit nervous. [00:37:49] And they would, if they always kind of start, they were like, you know what else I do? And we're like, tell us. And then they tell us something and they're like, we just know from experience. Experience that this works that this changes the ferment, but we don't have any evidence for that And and I think they're worried we're gonna judge them but we're like no that is like their science is all way of knowing but [00:38:09] my friend says art is science and love and and I love that idea that is something that's been really really fun about working with wineries and vineyards is they kind of get that they're like, yeah, this is the love piece here [00:38:22] Craig Macmillan: That's cool I think there's beauty in the mess. I might adopt that if you don't mind I mean, I may use that for some of my own stuff. I think that's great What is one thing you would tell growers or wineries, , [00:38:35] Aria Hahn: their choices are directly impacting the microbiome, so that's the bacteria and the yeast And that that is going to affect the terroir, the complexity, the quality of the wine, and it is knowable. [00:38:50] Craig Macmillan: there we go. And we also know that some of the things that we do may affect that and that is part of what makes us special. Where can people find out more about you? [00:38:58] Aria Hahn: We have a website, it is koonke. com, K O O N K I E dot com. can also look me up, Aria Hahn, , and on Google Scholar, the internet, I feel like I'm very findable. [00:39:10] Craig Macmillan: Yeah, you are very findable and we will have a lot of links and other things on the show page. So please check that out. Really fascinating stuff going even beyond this. I want to thank you for being on the podcast. [00:39:21] This has been a great conversation. [00:39:22] Aria Hahn: Yeah, thanks for having me. Super fun. [00:39:25] Craig Macmillan: So our guest today was Aria Hahn. She is CEO and co founder of Koonkie, a bioinformatics company, and is doing some really fascinating stuff, not only around yeast, but lots of other topics. [00:39:35] And I just got lost down the rabbit hole when I took a look at that website, all the different things you folks have been involved in, and it was really fun. [00:39:48] Beth Vukmanic: Thank you for listening. [00:39:49] Today's podcast was brought to you by Sunridge. For over 45 years, Sunridge nurseries has supplied premium quality grapevines. to grape growers worldwide. A pioneer in the industry with a focus on clean quality vines and personalized dedication to their partnered growers has led them to be the largest, most well respected grapevine nursery in the United States. Sunridge Nurseries continues to lead the industry having undergone several expansions to their modern state of the art facilities and is the first and only grapevine nursery to have implemented the most advanced greenhouse Horticulture water treatment technology in North America. [00:40:26] Make sure you check out the show notes for links to Aria, an article titled, make better wines with bioinformatics plus sustainable wine growing podcast episodes, 201 balance hot climate, high sugar wine with green grape juice, 243 microbial communities in the grapevine. And 251 vine sap analysis to optimize nutrition. [00:40:50] If you liked the show, do us a big favor by sharing it with a friend, subscribing and leaving us a review. You can find all of the podcasts at vineyardteam.org/podcast, and you can reach us at podcast at vineyardteam. org until next time, this is sustainable wine growing with the vineyard team.   Nearly perfect transcription by Descript

The Court of Appeal has just handed down the important decision of Higgs v Farmor's School, dealing with the circumstances when an employer can (or cannot) dismiss an employee for expressing gender critical views.  I recorded a 45 minute discussion about the ramifications of this case for employers, exclusively for members of the HR Inner Circle.  Here are the first few minutes of that recording for podcast listeners.

In this exclusive episode of Off Track Podcast, our host Dave Neal sits down with Stuart Higgs, the Series Director of the Bennetts British Superbike Championship (BSB). After a look back at the epic 2024 Season, Dave and Stuart then look ahead to 2025 as Stuart explains the series' switch to TNT Sports making this a must-listen for motorcycle racing fans, superbike enthusiasts, and BSB followers.Tune in for everything you need to know about the British Superbike Championship in 2025 and beyond!Keywords: British Superbike Championship, BSB 2025, Stuart Higgs, motorcycle racing podcast, superbike news, Bennetts BSB, racing strategy, motorsport interview, Off Track Podcast, BSB riders, TNT Sporthttps://racesafe.org/Send us a text Support the showWould you like early access to shows and the chance to ask questions of the guests? Well, you can, right here... https://www.patreon.com/join/9993138Off Track Merchandise: https://www.hmycustoms.co.uk/off-track-podcastRidinGraphics: https://www.instagram.com/ridingraphics/?hl=enhttps://www.facebook.com/demographics/?locale=en_GBFacebook: Off Track Podcast https://www.facebook.com/OffTrackTheMotorcycleRacingPodcast/ Instagram: @offtrackpodcastukhttps://www.instagram.com/offtrackpodcastuk/Twitter: @offtrack_https://twitter.com/OffTrack_ IG: @thedaveneal | Twitter: @daveneal | Facebook: Dave Neal

On October 27, 2008, Jodi Lynne Torok was at her Crofton, MD home talking on the phone with her close friend, Blair Wolfe, when a man, purporting to be a salesman, knocked on her front door. Jodi ended the call to respond to the so-called salesman, but thereafter never called Ms. Wolfe back or answered any of Wolfe's subsequent telephone calls. Growing increasingly concerned, Ms. Wolfe telephoned the victim's roommate, and requested that she leave work and return home to make sure that the victim was safe. Upon arriving at the residence that she shared with the victim, Ms. Higgs found the front door unlocked and the victim lying on the foyer, unconscious and bleeding from a gunshot wound to her head. At the time, she was two months pregnant. As a result of the gunshot wound, the victim's pregnancy was terminated, and she suffered severe and disabling injuries. The State developed a theory that, Charles Martin was in a relationship with the victim and upon learning of Torok’s refusal to obtain an abortion, solicited a friend to kill Torok and assisted Burks in the murder. The State charged Martin with solicitation of murder and accessory before the fact to attempted murder in the first degree. He was convicted and sentence to life in prison. To learn more and get involved, visit: https://appcounsel.org/ https://www.skadden.com/ Wrongful Conviction is a production of Lava For Good™ Podcasts in association with Signal Co. No1. We have worked hard to ensure that all facts reported in this show are accurate. The views and opinions expressed by the individuals featured in this show are their own and do not necessarily reflect those of Lava for Good.See omnystudio.com/listener for privacy information.

It's Thursday, February 13th, A.D. 2025. This is The Worldview in 5 Minutes heard on 125 radio stations and at www.TheWorldview.com. I'm Adam McManus. (Adam@TheWorldview.com) By Jonathan Clark and Adam McManus Iran arrested two Christians Article 18 reports that authorities in Iran arrested two Christians last Thursday.  Nasser Navard Gol-Tapeh and Joseph Shabazian are both in their 60s. They had previously spent a combined six years in prison for leading house churches. They originally received 10-year sentences, but were released part way through.  It's not clear why officials arrested Nasser and Joseph again. But the Middle Eastern country is known for arresting anyone who is not aligned with the Islamic regime on “security” charges. Iran is ranked ninth on the Open Doors' World Watch List of nations where it is most difficult to be a Christian.  In Matthew 5:10, Jesus said, “Blessed are those who are persecuted for righteousness' sake, for theirs is the kingdom of Heaven.” British Christian teacher vindicated for objecting to transgender agenda Yesterday, an appeals court in the United Kingdom ruled in favor of a Christian teacher who lost her job over her Facebook posts. A Church of England primary school in Gloucestershire fired Kristie Higgs in 2019. This came after she posted a petition on Facebook that opposed mandatory sex education in schools. She also posted an article that challenged transgender ideology.  Higgs has spent the last six years fighting the school's decision to fire her.  HIGGS: “Nobody should lose their job for raising concerns. The biggest thing for me was that it was a Church of England School. They should be going by what God says, but now they're changing it, and that's just alarming. Just to see a boy in girl's clothing. Another one, My Princess Boy. To some people, it may appear to be okay, but when you know the Lord, you know His ways, and you know a boy cannot be a princess. A boy shouldn't dress up in Princess' clothing. “I knew what these books were. I knew that it was wrong. I could see through it, and I praise God for that. I encourage others to stand up against the ideology and the agendas that are being pushed. You know, we don't have to, don't have to agree to everything. We don't have to go with the flow. The Lord is with us and will help us through it all.” After her victory yesterday, Higgs said, “I pray that today will prove to be a landmark day for Christian freedoms and free speech.  … The Court of Appeal has now set a clear standard to protect people like me, and the countless other Christians in this nation, to express their beliefs without fear of losing their jobs.” Trump chatted with Russian President Vladimir Putin U.S. President Donald Trump spoke over the phone with Russian President Vladimir Putin yesterday.  It's the first known conversation between the two leaders since the start of Trump's second term. Trump described the conversation as “lengthy and highly productive.” He announced the two countries would begin immediate negotiations for ending the war between Russia and Ukraine. Trump said he also had a good conversation with Ukrainian President Volodymyr Zelenskyy yesterday.  The conversations come as the United States and Russia complete a prisoner exchange this week.  Tulsi Gabbard confirmed as National Intelligence Director Former Democratic Congresswoman Tulsi Gabbard of Hawaii, who became a Republican and endorsed Donald Trump for President last October, has been confirmed by the U.S. Senate to the position of director of national intelligence, reports The Epoch Times. Gabbard was confirmed in a 52–48 vote on Wednesday. Senator Mitch McConnell of Kentucky was the only Republican to vote against Gabbard. SENATOR: “Yays are 52. Nays are 48. Nomination is confirmed.” Yesterday's confirmation follows a contentious few weeks of debate over Gabbard's qualifications and judgment, in which lawmakers from both sides of the aisle asked probing questions about her views on Russia, ousted Syrian dictator Bashar al-Assad, and Edward Snowden, the former National Security Agency contractor who leaked classified information. Listen to this exchange between Republican Senator Jerry Moran of Kansas and Gabbard on the topic of Russia as she appeared before the Senate Select Committee on Intelligence. MORAN: “I want to make certain that in no way does Russia get a pass in either your mind or your heart or in any policy recommendation you would make or not make.” GABBARD: “Senator, I'm offended by the question because my sole focus, commitment, and responsibility is about our own nation, our own security, and the interests of the American people. In carrying out the responsibilities of the Director of National Intelligence, if confirmed, no country, group or individual will get a pass in my fulfilling that responsibility of providing that full intelligence picture so that you all can make the best informed policy decisions for the safety, security, and freedom of the American people. “You have my commitment to be completely objective, unbiased, and apolitical. And I hope you understand my commitment to our country's interest.” MORAN: “I absolutely do. You have answered my question in the manner in which I wanted to hear, that you will do this in an objective manner, provide the information necessary, and that Russia, if it's a threat, you will tell us so and tell us the details of that threat.” GABBARD: “Yes. Senator.” After President Trump introduced her at the Oval Office, Gabbard was sworn in by Attorney General Pam Bondi. GABBARD: “I, Tulsi Gabbard, do solemnly swear, that I will support and defend the Constitution of the United States against all enemies, foreign and domestic, and that I will bear true faith and allegiance to the same. I take this obligation freely, without any mental reservation or purpose of evasion, that I will well and faithfully discharge the duties of the office on which I'm about to enter. So help me, God.” CDC website purged references to LGBTQ lifestyle and affirmed adoption The U.S. Centers for Disease Control and Prevention (CDC) is changing its website under the Trump administration. The CDC is editing or removing references on its website to “transgender” individuals, “LGBTQ+ health,” and diversity, equity and inclusion.  Its website also suggests adoption when people search for abortion. Trump: No more drag shows at Kennedy Center And finally, President Trump announced last Friday that he is removing liberal agendas from the John F. Kennedy Center for the Performing Arts. The national cultural center of the United States is located in Washington, D.C. Congress authorized the center in 1958, requiring it to be sustained through private funds. Trump said he fired multiple people on the center's board of trustees, becoming the chairman himself. He wrote on Truth Social, “Just last year, the Kennedy Center featured Drag Shows specifically targeting our youth — THIS WILL STOP.” Close And that's The Worldview on this Thursday, February 13th, in the year of our Lord 2025. Subscribe by Amazon Music or by iTunes or email to our unique Christian newscast at www.TheWorldview.com. Or get the Generations app through Google Play or The App Store. I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

¿Qué es la consciencia y cómo es posible que un montón de neuronas generen pensamientos, emociones y la sensación de ser "tú"? En este episodio de Por el Amor de Higgs, Javier Santaolalla y Enric F. Gel se sientan con Mariano Sigman, uno de los neurocientíficos más influyentes del mundo, para abordar una de las preguntas más alucinantes de la ciencia: ¿Cómo surge la consciencia en el cerebro? Desde lo que sabemos hasta lo que todavía es un misterio, exploramos las teorías más fascinantes, los experimentos más sorprendentes y las grandes preguntas sin respuesta. ¿Es la consciencia solo un truco del cerebro? ¿O hay algo más? Si alguna vez te has preguntado quién eres realmente… este episodio es para ti. Aquí les dejamos las redes del tremendo crack Mariano Sigman: https://www.instagram.com/mariuchu https://www.tiktok.com/@marianosigman ¡No olvides suscribirte, dejar tus comentarios y compartir tus propias reflexiones sobre este apasionante tema! Mail para cuestiones y reflexiones: porelamordehiggs@gmail.com Edición: Ike Leal https://www.instagram.com/ikefuti/

In this episode of "Insights into Technology," host Joseph Whalen delves into the escalating world of cybersecurity threats with a focus on the alarming rise in credential theft. The discussion covers the intricate details of sneak thief malware and its implications for enterprise environments, as security teams brace for the top 10 MITRE attack techniques. The episode also delves into the evolving role of artificial intelligence in particle physics, exploring how AI is transforming research at the Large Hadron Collider and its potential to unlock the universe's deepest mysteries. Additionally, it touches on the ethical considerations and security challenges posed by AI in espionage activities. Finally, the episode examines Microsoft's strategic push towards Windows 11, highlighting the hardware requirements and the broader implications for users and organizations facing a significant tech upgrade.

In this episode of "Insights into Technology," host Joseph Whalen delves into the escalating world of cybersecurity threats with a focus on the alarming rise in credential theft. The discussion covers the intricate details of sneak thief malware and its implications for enterprise environments, as security teams brace for the top 10 MITRE attack techniques. The episode also delves into the evolving role of artificial intelligence in particle physics, exploring how AI is transforming research at the Large Hadron Collider and its potential to unlock the universe's deepest mysteries. Additionally, it touches on the ethical considerations and security challenges posed by AI in espionage activities. Finally, the episode examines Microsoft's strategic push towards Windows 11, highlighting the hardware requirements and the broader implications for users and organizations facing a significant tech upgrade.

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 4, we are diving into the story of Jehu and Jezebel.

En esta segunda entrega sobre los grandes hitos científicos del siglo XXI, Pablo Fuente nos guía por un fascinante recorrido que incluye el descubrimiento del bosón de Higgs, la revolución de la inteligencia artificial, los avances en terapias psicodélicas, la exploración espacial privada y mucho más. Un episodio que nos recuerda que vivimos en una época de maravillas, donde la ciencia ficción de ayer se está convirtiendo en la realidad de hoy. Escucha el episodio completo en la app de iVoox, o descubre todo el catálogo de iVoox Originals

How much more physics is out there to be discovered? Neil deGrasse Tyson sits down with physicist, professor, and rockstar Brian Cox, to discuss everything from the Higgs boson, life beyond our planet, and the fundamental forces that guide our universe.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/our-world-of-particles-with-brian-cox/Thanks to our Patrons Anthony Sclafani, Alejandro Arriola-Flores, Brian Christensen, Allen Baker, Atlanta Gamer, Nigel Gandy, Gene, Lisa Mettler, Daniel Johansson, Sunny Malhotra, Omar Marcelino, yoyodave, Mo TheRain, William Wilson, ChrissyK, David, Prabakar Venkataraman, PiaThanos22, BlackPiano, Radak Bence, Obaid Mohammadi, the1eagleman1, Scott Openlander, Brandon Micucci, Anastasios Kotoros, Thomas Ha, Phillip Thompson, Bojemo, Kenan Brooks, jmamblat@duck.com, TartarXO, Trinnie Schley, Davidson Zetrenne, and William Kramer for supporting us this week. Subscribe to SiriusXM Podcasts+ on Apple Podcasts to listen to new episodes ad-free and a whole week early.

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 3, we are diving into the story of John the Baptist.

En este episodio de "Por el Amor de Higgs", Javier Santaolalla y Enric F. Gel se lanzan a debatir el famoso libro "El Espejismo de Dios" de Richard Dawkins. ¿Es la religión un simple producto de nuestra mente? ¿Qué papel juega la ciencia en estas preguntas tan profundas? Hablamos de los argumentos más potentes de Dawkins, los analizamos desde la filosofía y la ciencia, y debatimos si la fe y el pensamiento crítico pueden convivir. Prepárate para un diálogo que te hará replantearte muchas cosas. ¡No olvides suscribirte, dejar tus comentarios y compartir tus propias reflexiones sobre este apasionante tema! Mail para cuestiones y reflexiones: porelamordehiggs@gmail.com Edición: Ike Leal (@ikefuti) Bibliografía recomendada ► Edward Feser, Aquinas ► Gaven Kerr, Aquinas's Way to God ► Ángel Luis González, Ser y participación ► M. Rotta, Taking Pascal's Wager Demostración de "Si el ser necesario es posible, entonces existe" en S5: Definiciones: no = "no es el caso que" P = "es necesario que P" P = "es posible que P" P = no- no-P P = P (Axioma 5 de S5) P = P P = no- no-P Demostración: 1. P (Es posible que P sea necesario) 2. Suponemos: no-P (es posible que no-P) 3. no-P (Axioma 5) 4. no- no- no-P (por la definición de ) 5. no no-no- no-no-P (por la definición de ) 6. no P (no-no-X = X) 7. no no-P (Reduction del supuesto 2: 6 contradice 1) 8. P (por la definición ) 9. Ergo P

En este episodio de "Por el Amor de Higgs", Javier Santaolalla y Enric F. Gel se lanzan a debatir el famoso libro "El Espejismo de Dios" de Richard Dawkins. ¿Es la religión un simple producto de nuestra mente? ¿Qué papel juega la ciencia en estas preguntas tan profundas? Hablamos de los argumentos más potentes de Dawkins, los analizamos desde la filosofía y la ciencia, y debatimos si la fe y el pensamiento crítico pueden convivir. Prepárate para un diálogo que te hará replantearte muchas cosas. ¡No olvides suscribirte, dejar tus comentarios y compartir tus propias reflexiones sobre este apasionante tema! Mail para cuestiones y reflexiones: porelamordehiggs@gmail.com Edición: Ike Leal (@ikefuti) 📚 Bibliografía recomendada ► Edward Feser, Aquinas ► Gaven Kerr, Aquinas's Way to God ► Ángel Luis González, Ser y participación ► M. Rotta, Taking Pascal's Wager Demostración de "Si el ser necesario es posible, entonces existe" en S5: Definiciones: no = "no es el caso que" 🔲P = "es necesario que P" 🔶P = "es posible que P" 🔲P = no-🔶no-P 🔶P = 🔲🔶P (Axioma 5 de S5) 🔲P = P 🔶P = no-🔲no-P Demostración: 1. 🔶🔲P (Es posible que P sea necesario) 2. Suponemos: 🔶no-P (es posible que no-P) 3. 🔲🔶no-P (Axioma 5) 4. no-🔶no-🔶no-P (por la definición de 🔲) 5. no🔶no-no-🔲no-no-P (por la definición de 🔶) 6. no🔶🔲P (no-no-X = X) 7. no🔶no-P (Reduction del supuesto 2: 6 contradice 1) 8. 🔲P (por la definición 🔲) 9. Ergo P

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 2, we are diving into the story of David and Uriah.

Meet Michelle Higgs. She was a candidate for a Indiana State House District 60 in Morgan, Monroe & Johnson counties in southern Indiana. We have some post election talk that also includes great talk about "right sized candidates & messenger candidates."  We do have the freedom to loose forward. We have so much work to do. We know we are dealing with a democracy that is being sold away. We cover a lot of subjects in this episode. We provide some links below so you can learn more too. Our favorite quote from Michelle Higgs "A government of the people, means working with the people." Find her on the Socials here  Find her on BlueSky as MichelleHiggs linked here. On Facebook her campaign last fall had this page.  On YouTube you can find Michelle, follow the link here. Michelle Higgs campaign website from 2024 is here. Her Facebook page Michelle Higgs is linked here.  We mention the Poor Peoples Campaign - a link to learn more about their work is here. We talk about Moms Demand Indiana  - a link to their work is here. We also get into the Indiana Rural Summit and the work they are doing, follow the link here. In addition there was a great article last fall printed by In These Times Magazine the article was about the down ballot candidates in American rural areas and Michelle Higgs campaign was included in the article linked here. We also talk about the Dirt Road Revival book and the plan to do more Dirt Road Organizing follow these links to learn more about the book, and how you can be a part of the future you want to see. We talk about the work being done by the MAD Voters .org team - follow this link to learn more. This site is amazing and updated everyday during the 2025 Indiana legislative session. MAD in their name stands for Mutually Assured Democracy.  Special thanks to the CWA - The Communications Workers of America for their continued support of My Labor Radio. When you want to know more about Organizing a Union in your workplace, follow this link and reach out to a CWA Organizer to learn more about this important work & life changing decision. Special thanks to the MLPA for their support of our work. Find them at this link here to learn more. The Midwest Labor Press Association.  Special thanks to UAW2209.org for all their assistance and support for the work we do at My Labor Radio.  Thanks for listening, you can find us on all the Socials by following our LinkTreeLink here. 

Join us the next 7 weeks as we explore life lessons that can be found in the stories of murder in the Bible. Week 1, we are diving into the story of Cain and Abel.

David Higgs made his bones in the local dining scene in the mid- to late-‘naughties' when he helmed the multi-award winning Rust en Vrede restaurant in the Western Cape Winelands. Then he packed up and went to Jo'burg and chatter around this lively, entertaining and gifted chef got a bit quiet for a while. Then the buzz started about The Saxon's kitchen and he was in the awards lists again. In 2016, along with partner Gary Kyriacou, David opened Marble restaurant in Rosebank with its impressive wood-fired grill. It was all about live-fire cooking and a hell of a vibe - the toast of Johannesburg. Now he's opened Marble Cape Town. In the middle of a busy season, with one foot in the Mother City and the other in eGoli, David found some time to sit down for a chat about restaurants and the partners' baby; Pantry.Marble RestaurantPantry by MarbleSend us a text On Instagram @a_table_inthecorner Cover image sketched by Courtney Cara Lawson All profile portraits by Russel Wasserfall unless otherwise credited Title music: 'In Time' by Olexy via Pixabay

Uruguay apunta, desde hace tiempo, a posicionarse como un destino turístico atractivo a nivel mundial. Ubicado entre dos vecinos que lo superan en tamaño y en variedad de paisajes, nuestro país intenta destacarse a través de sus características propias, de su personalidad e identidad. ¿Cuáles son las fortalezas y debilidades de Uruguay para atraer visitantes? ¿Ofrece servicios de calidad? ¿Se ha logrado desestacionalizar la actividad turística más allá del verano? ¿Qué papel juega la tecnología en la promoción de Uruguay como lugar de paseo y disfrute? Para intentar responder estas y otras preguntas, vamos a conversar con dos personas que están inmersas en el tema. Por un lado, Karen Higgs. Ella nació en Gales, vivió en varios países y desde el año 2000 está radicada en Uruguay. Es, además, la autora de Guru'Guay, una guía (y sitio web) para viajar, vivir e invertir en nuestro país. Junto a Karen, vamos a contactarnos también con Ignacio Olivera, creador de contenidos turísticos en plataformas digitales. En los últimos años él se ha dedicado a recorrer el país y comparte imágenes e información en su página de Instagram “Turista en Uruguay”, que tiene casi 70 mil seguidores.

Join host Kristin Fitch as she welcomes Brittany Higgs, the founder and CEO of Her Campaign, a nonprofit dedicated to helping victims of human trafficking. Their conversation delves into the profound impact of hope and healing, showcasing the transformative work being done to support women who have experienced unimaginable trauma. Brittany shares her personal journey that led her to establish safe houses for survivors, emphasizing the holistic approach of addressing body, mind, and spirit in the healing process. Through their discussion, listeners will discover the importance of deepening one's relationship with God and how that connection can lead to powerful personal and communal healing. This episode serves as a reminder that even in the face of darkness, God's light and love can bring restoration and purpose to those who have suffered.Learn more about Her Campaign or connect with Britney at HerCampaign.orgDownload My Free Joyful Living Devotional: https://kristinfitch.com/devotionalReady to take your first step towards a more joyful, faith-filled life? Download our Reignite Your Passion Workbook and start living with purpose today!Ready to work with Kristin to make a shift in your life? Click here to get started.Ready to Reclaim Your Life? Purchase the Reclaim Your Life Masterclass: Protect Your Spirit, Space and Pace for only $47 Learn more here. Takeaways: Kristen shares how her heart broke for victims of human trafficking while hearing their stories. The importance of holistic healing for survivors, addressing body, mind, and spirit needs. Brittany emphasizes that each survivor is a whole person deserving of comprehensive care. God's healing power is transformative, allowing survivors to find purpose and hope again. Human trafficking is complex, often rooted in familial exploitation and vulnerabilities. The journey to healing involves recognizing one's identity in Christ and God's love. human trafficking, nonprofit organization, victims support, emergency shelter, long-term care, healing trauma, Christian women, faith-based initiatives, social justice, hope and healing, survivor stories, mental health, spiritual growth, community support, trafficking awareness, holistic care, trauma-informed care, faith and restoration, women's empowerment, anti-trafficking resources

Middle Tennessee CEO of the Boys and Girls Club Eric Higgs joined the show. Eric and the guys expressed their encouragement to bring jackets that you o longer wear and donate. Listen to hear more.

In the final hour of Chase and Big Joe Show, Forever Titans WR Chris Sanders joined the show. Chris shared his thoughts on the Titans starting Mason Rudoplh and shared a few laughs. Listen to hear more. They later had on the Middle Tennessee CEO of the Boys and Girls Club Eric Higgs. Eric and the guys expressed their encouragement to bring jackets that you o longer wear and donate. To end the show as always with celebrity birthdays and what day it is.  Who do you think will win? Listen to hear more.

What is autonomy supportive parenting, and why does it help with your kid? Hunter talks to Marcus Aurelius Higgs about the mistakes we often make communicating with our kids and how to instead empower kids and support their growth. They cover practical examples and strategies for dealing with challenging behaviors and communication issues. ABOUT HUNTER CLARKE-FIELDS: Hunter Clarke-Fields is the host Mindful Parenting Podcast (Top 0.5% podcast ), global speaker, number 1 bestselling author of “Raising Good Humans” and “Raising Good Humans Every Day,” Mindfulness Meditation teacher and creator of the Mindful Parenting Course and Teacher Training. Find more podcasts, Hunter's books, blog posts, free resources, and more at MindfulMamaMentor.com. Discover your Unique-To-You Podcast Playlist at mindfulmamamentor.com/quiz/ We love the sponsors that make this show possible! You can always find all the special deals and codes for all our current sponsors on our website: /mindfulmamamentor.com/mindful-mama-podcast-sponsors/ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Marcus Aurelius Higgs shares his poetry in Divine essence. We have a great discussion about what is gratitude, wisdom and how life supports those who support life. BIOMarcus is a communication coach for parents of preteens (ages 10-14). He helps them show up and maintain a meaningful relationship with their child through communication during these crucial formative years.The clients he works with know the value of doing hard things and want to connect with their tween before it's too late to bridge the gap.With a multicultural background himself—born to a Filipino mother and a Bahamian father—Marcus finds particular joy in supporting families to communicate across generational and cultural divides. Marcus Aurelius Higgs(8) Facebook(44) M. Aurelius Higgs | LinkedIn#alittlelessfearpodcast #drlinomartinez #linomartinezpsyd #lino #podcast #podcastshow #author #authors #poets #poetry #poems #poem #poetrylovers #poetrylover #poetrycommunity #transcendence #humanities #beauty #gratitude #life #love #wisdom #wellbeing #beliefs #spiritualgrowth #communication #emotions #religionandspirituality #storytelling #tweens #teens #fyp #foryoupage #foryourpage #foryou This is Dr. Lino Martinez the host for A Little Less Fear Podcast. For more information, please use the information below. Thanks so much for your support!Author | A Little Less FearA Little LESS FEAR Podcast (@alittlelessfearpodcast) • Instagram photos and videosLino Marinez (@alittlelessfear) TikTok | Watch Lino Marinez's Newest TikTok Videos(4) A Little Less Fear Podcast - YouTube

In late September, I had the honour of recording a conversation with the late Professor Ian Shipsey, Head of Physics at Oxford University. Tragically, Professor Shipsey passed away shortly after our discussion. We are releasing this episode as a tribute to his remarkable contributions. Professor Shipsey was one of the leading particle physicists of his generation and was Head of Physics at Oxford from 2018 until his passing. His groundbreaking work ranged from studying subatomic particles to advancing our understanding of the Higgs boson, discovered at CERN in 2012. In recognition of his extraordinary contributions, he was elected a Fellow of the Royal Society in 2022. In this podcast, we discussed climate change and renewable energy, quantum computing, and how physics can change the world around us.

What happens when a former British Army captain turns into a best-selling mystery and thriller author? Join us for an eye-opening conversation with Steve Higgs, whose journey from the military to full-time writing is as compelling as his novels. We talk about his transformation from soldier to scribe, sharing how his initial lack of support only fueled his desire to write. Discover how his debut novel, "Paranormal Nonsense," became a reality and how Steve's story is a testament to the power of following your creative passions despite life's roadblocks.Get ready to recharge your writing habits as we unpack the secrets to maintaining a regular writing schedule. Learn why discipline, often honed in military settings, can be your greatest ally in keeping the creative juices flowing. With Steve's humorous anecdotes on character creation and genre-hopping—from urban fantasy to cozy mysteries—you'll be inspired to embrace your unique writing style. We also touch on the challenges of balancing your craft with personal commitments, and why motivation doesn't always come from where you expect.Finally, we tackle the myth of overnight success and share practical tips on navigating the path to author stardom. Discover how networking and learning from experienced authors can accelerate your journey. This episode is packed with insights on everything from marketing strategies to the unpredictable nature of success. Plus, we're excited to announce a series of fiction-focused episodes coming in November, just in time to boost your NaNoWriMo efforts. Whether you're a seasoned author or just starting out, you're sure to find inspiration and practical advice to fuel your writing journey.Watch the free training: https://selfpublishing.com/freetrainingSchedule a no-cost call with our team: https://selfpublishing.com/schedule Here are some links that might come in handy: Apply for a free book consultation Register for our free on-demand training Must-watch episodes: SPS 044: Using A Free + Shipping Book Funnel with Anik Singal SPS 115: Using Atomic Habits To Write & Publish A Book with James Clear SPS 127: Traditional vs. Self Publishing: Which You Should Choose with Ruth Soukup SPS 095: The Five Love Languages: Selling 15 Million Copies with Gary Chapman SPS 056: How I Sold 46M Copies of My Self Published Book with Robert Kiyosaki

✨ Can you truly *connect* with your preteen before the gap becomes too wide? ✨ In this episode, Marcus Higgs reveals the secret to navigating the "identity-breaking" years of 10-14 using his SHOW UP Framework.

Sarah Higgs shares how to defeat distractions that sabotage your network marketing business and simple solutions that'll help you winWho is Sarah HiggsSarah Higgs had a rough childhood where her mom passed away and her dad was an alcoholic.This led to a life of self sabotage which Sarah fortunately was able to change and turn her life around.She eventually worked in a corporate role at a stockbroker before she transitioned to being a stay at home mom. This ultimately led her to pursue a flexible career path and that's how she discovered network marketing 16 years ago.Today she's a full time leader with hundreds of customers.Sarah takes pride in using systems to run a successful home business which doesn't take time away from her 4 kids.SummarySarah's childhood struggles shaped her resilience and determination.Recognizing self-sabotage is the first step to overcoming it.Mindset plays a crucial role in achieving success in network marketing.A life-changing moment can propel you into action.Breaking through limiting beliefs can lead to significant growth.Confidence comes from taking action, even when uncomfortable.Learning from adversity is essential for personal growth.Consistency and systems are key to running a successful business.Identifying distractions helps in maintaining focus and productivity.Creating a supportive environment can enhance accountability. Having a dedicated workspace can significantly enhance productivity.Discipline is crucial for maintaining focus during work hours.Constructive working time is more effective than long hours of distraction.Changing your environment can lead to better performance.Accountability is key to personal and professional growth.Communication with family about work hours is essential.Investing in the right tools and environment fosters growth.Building connections through social media is vital for network marketing.Taking positive action daily leads to success.You are in control of your own life and outcomes.Quotes from Sarah Higgs"I walked away from all my friends.""I realized I was sabotaging myself.""What if I just try?""You have to do it anyway.""Consistency is definitely key.""Having an office is a game changer.""You are in control of your own life.""You can do it, you are capable of it."Chapters00:55 From Struggles to Success: Sarah's Journey04:02 Overcoming Self-Sabotage and Building Worthiness06:44 The Power of Mindset in Network Marketing09:46 Discovering Network Marketing: A Life-Changing Moment12:038Breaking Through Limiting Beliefs15:12 Building Confidence and Taking Action18:01 Learning from Adversity: Key Moments in Network Marketing19:58 Consistency and Systems: Keys to Success21:55 Managing Distractions in a Home Business24:49 The Power of a Dedicated Workspace27:50 The Importance of Focus and Discipline31:08 Creating the Right Environment for Growth33:34 Accountability and Personal Responsibility38:07 Building Connections in Network MarketingFavorite Quotes Feel the fear and do it anywayFavorite Prospecting ToolFace to Face or ZoomRecommended AppsManychatRecommended BooksSeven Habits of Highly Effective People by Stephen CoveyBuilding a Story Brand by Donald MillerEat That Frog by Brian TracyGirl Boss by Sophia AmorusoRecommended Prospecting ToolFacebook ATM MethodSarah Higg's Contact InfoFacebookInstagram

What if you could transform a strict military career into a flourishing life as a bestselling author? That's exactly what Steve Higgs, a former British Army captain, accomplished. Join us on the Self-Publishing School Podcast, where Steve shares his incredible journey from the army to becoming a successful mystery and thriller author. Despite facing significant challenges and a lack of support from his family, he persisted and published his debut novel while still in the army. Steve's resilience and perseverance offer a powerful message to aspiring writers hesitant to take the first step in their own creative journeys.Balancing a demanding full-time job with a writing career is no small feat, yet Steve has mastered the art of maintaining momentum through disciplined writing habits. Our discussion uncovers practical strategies for fitting writing into a busy life, dispelling the myth that certain backgrounds are a prerequisite for writing success. By managing creative overflow and maintaining focus, Steve demonstrates how anyone can cultivate the discipline needed to achieve their writing goals. We also explore his transition from urban fantasy to cozy mystery, illustrating the spontaneity and creativity that fuel his storytelling.The importance of community and perseverance in the writing world cannot be overstated. From emotionally charged writing moments to navigating the author community, our episode highlights the value of connecting with fellow writers to overcome the isolation often felt in this profession. Steve's journey is a testament to the power of networking, strategic marketing, and relentless passion that can propel an author from obscurity to success. As we celebrate NaNoWriMo, we invite you to expand your fiction skills and join us for upcoming episodes filled with insights and inspiration.Watch the free training: https://selfpublishing.com/freetrainingSchedule a no-cost call with our team: https://selfpublishing.com/schedule Here are some links that might come in handy: Apply for a free book consultation Register for our free on-demand training Must-watch episodes: SPS 044: Using A Free + Shipping Book Funnel with Anik Singal SPS 115: Using Atomic Habits To Write & Publish A Book with James Clear SPS 127: Traditional vs. Self Publishing: Which You Should Choose with Ruth Soukup SPS 095: The Five Love Languages: Selling 15 Million Copies with Gary Chapman SPS 056: How I Sold 46M Copies of My Self Published Book with Robert Kiyosaki

Harry Higgs is back on the pod and headed back to the PGA Tour! We talked with Harry about his year on the KFT and how he improved his game to earn his tour card back. We also cover his mental health and revisit his comments surrounding the passing of Grayson Murray, learning to take time off during the season, getting recognized abroad, and his view of the current state of the PIF negotiations. If you enjoyed this episode, consider joining The Nest: No Laying Up's community of avid golfers. Nest members help us maintain our light commercial interruptions (3 minutes of ads per 90 minutes of content) and receive access to exclusive content, discounts in the pro shop, and an annual member gift. It's a $90 annual membership, and you can sign up or learn more at nolayingup.com/join Support Our Partners: Pinehurst The Stack System fanduel.com/nlu Learn more about your ad choices. Visit megaphone.fm/adchoices

As an experimental facility, the Large Hadron Collider at CERN in Geneva has been extraordinarily successful, discovering the Higgs boson and measuring multiple features of particle-physics interactions at unprecedented energies. But to theorists, the results have been somewhat frustrating, as we were hoping to find brand-new phenomena beyond the Standard Model. There is nothing to do but to keep looking, recognizing that we have to choose our methods judiciously. I talk with theoretical physicist Cari Cesarotti about what experimental results the modern particle physicist most looks forward to, and how we might eventually get there, especially through the prospect of a muon collider.Support Mindscape on Patreon.Blog post with transcript: https://www.preposterousuniverse.com/podcast/2024/09/16/289-cari-cesarotti-on-the-next-generation-of-particle-experiments/Cari Cesarotti received her Ph.D. in physics from Harvard University. She is currently a postdoctoral fellow at MIT. Her research is on particle phenomenology theory, with an eye toward experimental searches. Among her awards are the Sakurai Dissertation Award in Theoretical Physics from the American Physical Society and the Young Scientist Award at the 14th International Conference on the Identification of Dark Matter.Web siteMIT web pagePublications at inSpireSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.