Podcasts about exciting

WATCH THIS EPISODE ON YOUTUBE!! Jeff and Zack are in the studio chatting all things fall bear! ITs finally here folks! Fall hunting season 2026 is on the doorstep and its EXCITING!!! LFG LINKS: KUIU GEAR - https://kuiu.sjv.io/GK1o7m EXO MOUNTAIN GEAR - https://exomtngear.com?ref=4 VORTEX OPTICS - https://alnk.to/cSJYlok MARSUPIAL GEAR - https://alnk.to/5FcU7YA ZOLEO - https://tinyurl.com/428ydbua PNWILD - https://www.pnwild.com/store-snytH DEVOS OUTDOOR LIGHTING - https://rstr.co/devosoutdoor/15643 COUPON CODES: OLLIN DIGISCOPE - PNWILD CANYON COOLERS - PNWILD10 VORTEX CLOTHING - PNW20 ZOLEO SATELLITE - PNWILD (Free Activation) VELOTRIC E-BIKES - PNWildN2X01 PNWILD - YOUTUBE If you want to learn more about PNWild visit https://pnwild.com/ INSTAGRAM: @pnwild_ https://www.instagram.com/pnwild_/?hl=en FACEBOOK: / pnwild TIKTOK: @pnwild_ / pnwild_ Got questions? Send us an email! Email: contact@pnwild.com Find all PNWild Partners and Codes here: https://www.pnwild.com/partners

What happens when a Grammy-nominated artist like Lukas Graham takes a stroll down memory lane? Join host Buzz Knight in this captivating episode of the Takin a Walk podcast as he delves deep into the life and music of Lukas Graham, the creative mind behind the global hit 'Seven Years. ' This conversation is not just about music; it's an exploration of music history, personal stories, and the emotional connections that shape an artist's journey. As the Buzz Knight podcast unfolds, Lukas shares his latest single 'To Know a Girl,' a track that marks a significant departure from his previous work, showcasing a more intimate and story-driven sound. Discover how his upbringing in the unique neighborhood of Christiania in Copenhagen has influenced his music and shaped his identity. Lukas reflects on his early experiences with music, from attending concerts to the profound impact of his father's work in the industry, providing listeners with a rich tapestry of music inspiration stories. This episode also dives into the creative process behind Lukas's upcoming album, highlighting the collaborative spirit that drives his work. Buzz Knight and Lukas discuss specific songs, including 'Before You Go,' which carries deep personal significance for the artist. The conversation elegantly weaves through themes of nostalgia, connection, and the emotional experience of performing live, especially when sharing deeply personal songs with audiences. As they walk through these inside music stories, Lukas reflects on his upcoming tour with Ed Sheeran, sharing his desire to take a walk with his late father and John Lennon. This heartfelt discussion about songwriting and their shared love of music adds a poignant layer to the episode, reminding us of the music and resilience that defines an artist's life. Don't miss this episode of Takin' a Walk with Buzz Knight, where legendary musicians like Lukas Graham share their journeys, struggles, and triumphs. Tune in for an inspiring ride through music history, filled with unforgettable moments and insights that resonate with anyone who loves music. Whether you're a fan of iconic musicians or simply curious about the Nashville music scene, this episode promises to deliver a wealth of knowledge and inspiration. Join us as we celebrate the art of storytelling through music, revealing the career breakthroughs and legendary music moments that shape our favorite songs. Experience the magic of takin' a walk with Buzz Knight and Lukas Graham!Support the show: https://takinawalk.com/See omnystudio.com/listener for privacy information.

Which recruit from Tennessee football has had you the most fired up? Is it DGG, is it Jalen Hurd? Do Tell! ---------- TalkSports is LIVE Weekdays from 8-11 a.m. on Fox Sports Knoxville/ Fanrun Radio. Check Out our Socials: "@FOXSportsKnox" on Twitter/X, "FanrunSports" on Instagram and Youtube Jon- @Jon__Reed on "X" Sam- @_beard11 on "X" Bubba- @BrandonShown on "X"

What happens when a Grammy-nominated artist like Lukas Graham takes a stroll down memory lane? Join host Buzz Knight in this captivating episode of the Takin a Walk podcast as he delves deep into the life and music of Lukas Graham, the creative mind behind the global hit 'Seven Years. ' This conversation is not just about music; it's an exploration of music history, personal stories, and the emotional connections that shape an artist's journey. As the Buzz Knight podcast unfolds, Lukas shares his latest single 'To Know a Girl,' a track that marks a significant departure from his previous work, showcasing a more intimate and story-driven sound. Discover how his upbringing in the unique neighborhood of Christiania in Copenhagen has influenced his music and shaped his identity. Lukas reflects on his early experiences with music, from attending concerts to the profound impact of his father's work in the industry, providing listeners with a rich tapestry of music inspiration stories. This episode also dives into the creative process behind Lukas's upcoming album, highlighting the collaborative spirit that drives his work. Buzz Knight and Lukas discuss specific songs, including 'Before You Go,' which carries deep personal significance for the artist. The conversation elegantly weaves through themes of nostalgia, connection, and the emotional experience of performing live, especially when sharing deeply personal songs with audiences. As they walk through these inside music stories, Lukas reflects on his upcoming tour with Ed Sheeran, sharing his desire to take a walk with his late father and John Lennon. This heartfelt discussion about songwriting and their shared love of music adds a poignant layer to the episode, reminding us of the music and resilience that defines an artist's life. Don't miss this episode of Takin' a Walk with Buzz Knight, where legendary musicians like Lukas Graham share their journeys, struggles, and triumphs. Tune in for an inspiring ride through music history, filled with unforgettable moments and insights that resonate with anyone who loves music. Whether you're a fan of iconic musicians or simply curious about the Nashville music scene, this episode promises to deliver a wealth of knowledge and inspiration. Join us as we celebrate the art of storytelling through music, revealing the career breakthroughs and legendary music moments that shape our favorite songs. Experience the magic of takin' a walk with Buzz Knight and Lukas Graham!Support the show: https://takinawalk.com/See omnystudio.com/listener for privacy information.

Exciting stuff at North Park Beer Co. this week as they after many years have taken control of their kitchen at the North Park Tap Room. As Saturday kicks off thier Grand Opening, Kelsey from NPBC drops in all week to talk about what he's been cooking in the brewery, starting with a collab with Highland Park Brewery in LA, Timbo Pils!

Do you ever get bored eating healthy? You're not alone! In this episode, I'm sharing simple ways to make healthy meals more exciting using restaurant-inspired ideas, easy flavor boosters, homemade sauces, and fresh ingredients. You'll also learn why changing your taste buds takes time and why lasting weight loss is about more than just finding new recipes. If you're ready to enjoy healthy eating without feeling deprived, this episode is for you. Mentioned in this episode:

Send us Fan MailWhat are the most common eye injuries in children—and how can parents help prevent them?In this episode of Your Child Is Normal, Dr. Jessica Hochman sits down with Dr. Aaron Nagiel, pediatric retinal specialist and Chief of the Retina Division at Children's Hospital Los Angeles, to discuss children's eye health, vision safety, and the latest breakthroughs in retinal care.Dr. Nagiel explains how the retina works, common retinal conditions seen in children, and the warning signs parents should never ignore. He shares real-world stories about sports injuries, Nerf gun accidents, and laser pointer injuries that can lead to permanent vision loss, while offering practical advice on prevention and eye protection.They also discuss:• Common eye injuries in children and how to prevent them• When a red eye is concerning—and when it isn't• Warning signs of retinal disease• The role of screens, outdoor play, and dry eyes• Why children should wear prescribed glasses consistently• When eye symptoms warrant an urgent evaluation• Exciting advances in gene therapy and the future of pediatric retinal careThis episode is packed with practical takeaways that can help parents recognize problems early, protect their children's vision, and know when to seek specialized care.Dr. Aaron Nagiel is a pediatric retinal specialist at Children's Hospital Los Angeles and USC Roski Eye Institute, where he cares for children with retinal diseases, eye trauma, retinopathy of prematurity, and inherited retinal disorders. In collaboration with the Center for Personalized Medicine, he leads a state-of-the-art program specializing in the diagnosis and treatment of genetic eye disease, including gene therapy surgery.Dr. Aaron Nagiel earned his bachelor's degree from Harvard University summa cum laude, and then underwent combined MD and PhD training at Cornell University and The Rockefeller University in New York City. His PhD work was supported by an NIH fellowship and contributed to our understanding of how synapses form in the developing brain. After an internship at Memorial Sloan-Kettering Cancer Center, Dr. Nagiel completed both ophthalmology residency and vitreoretinal fellowship at the renowned Stein Eye Institute at UCLA.To contact Dr Nagiel:Please call 323-361-2347 or check out his websiteYour Child is Normal is the trusted podcast for parents, pediatricians, and child health experts who want smart, nuanced conversations about raising healthy, resilient kids. Hosted by Dr. Jessica Hochman — a board-certified practicing pediatrician — the show combines evidence-based medicine, expert interviews, and real-world parenting advice to help listeners navigate everything from sleep struggles to mental health, nutrition, screen time, and more. Follow Dr Jessica Hochman:Instagram: @AskDrJessica and Tiktok @askdrjessicaYouTube: Ask Dr JessicaShop my favorite products for kids on Amazon hereIf you are interested in placing an ad on Your Child Is Normal click here or fill out our interest form.For a plant-based, USDA Organic certified vitamin supplement, check out : Llama Naturals Vitamin and use discount code: DRJESSICA20To test your child's microbiome and get recommendations, check out: Tiny Health using code: DRJESSICA The information ...

Rochester Knighthawks General Manager Dan Carey joins the show as the team has announced that it will be going back to the purple & teal. Exciting times & we can't wait! Dan also talks about new head coach Troy Cordingley, the league as a whole, the offseason, the schedule & more.

World Cup Final Preview   Home Run Derby.....Exciting Finish   Baseball All Star Game: A Big Yawn

Fantasy Football show for July 18, 2026. Bears, Packers, Vikings, Lions! Exciting division for fantasy football! Full breakdown of the NFC North division with offseason changes, and expectations for the 2026 season. Plus, how to deal with inactive leaguemates in fantasy football. Manage your redraft, keeper, and dynasty fantasy football teams with the #1 fantasy football podcast. 2026 ULTIMATE DRAFT KIT is available now at UltimateDraftKit.com Get MEGALASHOW tickets at BallersLive.com Connect with the show: Subscribe on YouTube Visit us on the Web Support the Show Follow on X Follow on Instagram Join our Discord Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Full show notes: https://bengreenfieldlife.com/lotus In this episode with KJ Dhaliwal of Lotus AI, you'll hear how translating his immigrant parents' doctor visits as a child and years spent bouncing through fragmented specialty care as a teenager after a disc herniation shaped his mission to give 100 million Americans free, world-class primary care using AI. KJ breaks down how Lotus AI pulls your entire medical history from every clinic and hospital you've ever visited in minutes, unifies it with your wearables and genetic data, and makes it available to both a conversational AI and a network of real licensed physicians who can diagnose you, prescribe treatment, and refer you to a specialist in under two minutes at any hour of the day. We also touch on why hospitals are quietly selling your health data to pharma, how the business model works when the product is free, and why KJ believes the AI-powered general doctor is not just possible but already happening. KJ Dhaliwal is the founder and CEO of Lotus AI. Before Lotus, he co-founded the largest South Asian dating app, which he grew and sold. At Lotus AI, his mission is to collapse the cost of healthcare delivery while making world-class primary care free and permanently accessible to every American. Download the Lotus AI app here. If you are a physician, visit lotus.ai and sign up for Lotus Cortex. Episode Sponsors: Anthros: You can train hard and still undo a lot of that progress by sitting for the next eight hours, which is why Anthros takes a different approach, starting with a Precision Posture System at the pelvis so your spine naturally aligns, plus a built-in Clinical Posture Consult that helps identify issues you may not even realize you have. Go to anthros.com and use code BEN for an exclusive $200 discount and try it risk-free for 60 days. Timeline: Give your cells new life with high-performance products powered by Mitopure, Timeline's powerful ingredient that unlocks a precise dose of the rare Urolithin A molecule and promotes healthy aging. Mitopure now starts at $79 when you go to timeline.com/BEN. Quantum Upgrade: Recent research has revealed that the Quantum Upgrade was able to increase ATP production by a jaw-dropping 20–25% in human cells. Unlock a 15-day free trial with the code BEN15 at quantumupgrade.io. Dr. Murray Natural Products – ThymoQuin®: ThymoQuin® is a clinically researched black seed oil formulated to support healthy cortisol levels, improve resilience to everyday stress, and promote overall well-being. It's the only black seed oil that meets U.S. Pharmacopeia guidelines and is backed by human clinical research. Visit doctormurray.com/ben and use code BEN25 for 25% off all Dr. Murray Natural Products. Qualia Stem Cell: Qualia Stem Cell is a science-backed supplement designed to support your body’s natural repair system by enhancing stem cell function, helping you recover, renew, and maintain healthy tissues as you age. Taken just four days per month and formulated with premium, clinically supported ingredients, it’s an easy way to support long-term healing and vitality. Visit qualialife.com/boundless and use code BOUNDLESS for 15% off.See omnystudio.com/listener for privacy information.

Quantum materials discovery shows how quantum computing can create real value in industry by working alongside AI, advanced computing, and experiments to better understand materials, improve decision-making, and accelerate innovation at scale, ultimately helping deliver practical, measurable progress for the energy transition.This week, Dave, Esmee, and Rob are joined by co-host and quantum expert Phalgun Lolur, together with Jonathan Owens, Senior Scientist in Computational Materials Physics at GE Vernova to explore how quantum computing could reshape materials discovery and why that matters for the future of energy.  TLDR00:00 – Introduction01:50 – Hang out: The wet-bulb thermometer03:20 – Dig in: Technology Convergence and the Link to Quantum11:30 – Conversation with Jonathan Owens44:26 – Exciting to see how the quantum landscape matures and the magic wand for magnetismGuestJonathan Owens: https://www.linkedin.com/in/jonathan-r-owens-phd/ HostsDave Chapman:  https://www.linkedin.com/in/chapmandr/Esmee van de Giessen:  https://www.linkedin.com/in/esmeevandegiessen/Rob Kernahan:  https://www.linkedin.com/in/rob-kernahan/Co-host Phalgun Lolur:  https://www.linkedin.com/in/phalgun-lolur/ ProductionMarcel van der Burg:  https://www.linkedin.com/in/marcel-vd-burg/Dave Chapman:  https://www.linkedin.com/in/chapmandr/ SoundBen Corbett:  https://www.linkedin.com/in/ben-corbett-3b6a11135/Louis Corbett:   https://www.linkedin.com/in/louis-corbett-087250264/ 'Realities Remixed' is an original podcast from Capgemini

Dive into the world of craft malt, regional ingredients, and sustainable agriculture as we chat with Brad Humbert, owner of Bear Branch Malt in Maryland. Discover how local grains and farming practices shape the beer landscape in the Mid-Atlantic.Main Topics:The journey of local and craft malting in MarylandBridging agriculture and brewing through regional ingredientsSustainability and farm-to-brew relationshipsChallenges and opportunities for grain and hop growers in the Mid-AtlanticUpcoming events and collaborations for craft malt month>In this episode:Brad shares his background and the history of Bear Branch Malt, a family farm with roots dating back to 1937Discussion on the transition from engineering to craft malting, and love for regional ingredientsThe significance of local grains like Avalon barley and their terroir impactHow farm practices, including growing soybeans and cover crops, support sustainable malt productionThe relationship between local brewers and maltsters, and the importance of supporting regional grain economiesChallenges faced by hop growers in Maryland and the scalability issues of hop cultivationStrategic growth and expansion plans for Bear Branch Malt, including collaborations with breweries outside MarylandHighlighting upcoming craft malt and beer events, Oktoberfest releases, and the return of Sally GasterThe importance of community support and supporting local ingredients in the craft beer scene>Timestamps:00:00 - Welcome to the DC Beer Show and introductions00:14 - Mike Stein shares his drink: Liquidity Aleworks Patapsco Pale00:34 - Jordan's Canadian triple hazy IPA from Colorado01:09 - Brandy's smoked beer from Elder Pine02:00 - JB's concentration on Port City Schwarzbier and West Coast IPA03:01 - Introduction to Bear Branch Malt and Brad's drink: German-style red lager03:25 - Brad shares his journey from engineer to maltster and farm-to-brew philosophy04:46 - The evolution of the farm's malting system—from half-ton to 8-ton setup05:10 - Brad discusses what drives his passion for local agriculture and malting07:01 - Discussion on supporting local malting and regional ingredients07:32 - Clarifying that Bear Branch Malt sells malt, not animals08:21 - Connection between spent grain, livestock, and sustainability practices08:45 - The farm's integrated approach with cattle, sheep, and crop rotation09:19 - Potential differences in beef fed on malted grains09:39 - Local breweries' use of spent grain and farm practices involving malting byproducts10:36 - Exciting crops like Avalon barley for next year's harvest and terroir studies11:14 - The farm's crop cycle, planting seasons, and interesting cover crop experiments12:08 - The challenge of growing spring vs. winter grains like barley and wheat14:00 - The competitiveness of malting industry and regional grain support15:02 - The impact of commodity malt prices and value of local grains16:11 - The scope of grain farming and malt production in Maryland and neighboring states16:40 - The scale of craft brewing versus large-scale barley and hop production17:04 - Industry competition and collaboration among craft maltsters19:05 - Family farm history and historic ownership since 193720:10 - Community and event plans for Craft Malt Month and collaborations21:17 - Potential for regional hop growing and the limitations faced in the Mid-Atlantic22:25 - Challenges of growing proprietary hop varieties in Maryland23:39 - Yields and considerations for hop farming at small and larger scales25:42 - The significance of regional grain and malt industries across Maryland, DC, Virginia27:29 - Growth plans for Bear Branch Malt and expansion into neighboring states28:51 - Collaborations with local breweries like Monument, Union, and Guinness29:07 - Upcoming events at Other Half and local craft beer highlights30:36 - The role of cocktails versus beer and local bar culture31:12 - Celebrating Oktoberfest releases and upcoming beer festivals33:45 - Sally Gaster returning and upcoming fall events including the World Cup final34:17 - Closing remarks and support for local ingredients and community engagementResources & Links: • Bear Branch Malt - Maryland-based craft maltster and farmThank you for tuning in! Follow what's happening in the DC scene at DCBeer.com and @dcbeer on social media. Support us at Patreon.com/DCBeer Thanks to our monthly supporters Chris Sadler Brian Dauernheim Quinten Patterson C Sandoval Gilbert Glickstein Ethan Sapperstein Sean Whipkey Randy Mills Ryan Llalan Fowler Michael Losi Adam Heisenberg Brian Jeff Lucas Micaela Carrazco Lauren Sean Moffitt Anthony Scipione johnna infanti Catherine Ramirez Adam Frank Tyler Lynch Jared Prager Jeff Michael O'Connor Favio Garcia Josh Ellen Daniels Juan Deliz Mike Lastort James Wisnieski Chris Frome Sam Chip Tory Roberts Chris DeLoose Lauren Cary Clifton B Scott Pavlica Greg Antrim jeffrey garrison Alexis Smith Dan Goldbeck Anthony Budny Greg Parnas Frank Chang Kim Klyberg Chris Girardot Alyssa jeffrey katz Andrew MacWilliams Jamie Jackson Meegan Mike Rucki Nick Gardner Amber Farris Sarah Ray Peter Jones Blue2026 Brad Stengel Bill and Karen Butcher Jordan Harvey Stephen Claeys Julie Verratti

Questions? Thoughts? Send a Text to The Optometry Money Podcast! We'll answer your question on the show.In this rewind of a popular episode, Evon welcomes Dr. Chad Fleming back to The Optometry Money Podcast. Dr. Fleming shares his experiences with strategic planning and explains how setting aside time to work on the business through a strategic planning week has helped him scale his practice operations. They discuss how private practice owners can improve leadership, reduce chaos, and increase profitability through intentional planning.Evon and Dr. Fleming dive into the nuts and bolts of what a strategic planning week entails, how to execute it, and why it's essential to long-term business success.In This Episode:What's the difference between growth and scale for optometry practices?The concept of working on vs. in your business and why stepping away is crucial.What happens to a practice and the owner when there's no intentional planning time.How Dr. Fleming's annual strategic week helped him plan, lead, and reduce turnover.Practical advice on creating a productive planning getaway—from choosing a location to preparing resources.Measuring and implementing your strategic ideas when you return to the practice.Episode Highlights:[00:04:40] Scaling vs. growth: defining both for practice owners[00:06:10] Working on your business versus working in it: practical examples[00:18:22] Dr. Fleming's annual strategic planning getaway explained[00:23:05] How to prepare and gather your thoughts for a productive planning session[00:35:00] Tracking key performance indicators (KPIs) to measure success[00:40:06] Exciting opportunities in the future of private practice optometryResources:Contact Dr. Chad Fleming: Email him at chad@pipgpo.comLinkedIn: Connect with Dr. Fleming on LinkedInPast Podcast Episodes: Check out more episodes with Dr. Fleming in our podcast archive:Ep. 118: Adding Private Label to Improve Margins Without Compromising Quality with Dr. Chad FlemingEp. 17: Assessing the Health of Your Optometry Practice with Dr. Chad FlemingEp. 6: Navigating Associate Contracts, Practice Ownership, and Partnerships with Dr. Chad FlemingConnect With Us:For more podcast episodes, blog articles, and optometry-specific financial resources, visit www.optometrywealth.com.To learn more about working with Evon and the team at Optometry Wealth Advisors, CLICK HERE to schedule a free consultation.The Optometry Money Podcast is dedicated to helping optometrists make better decisions around their money, careers, and practices. The show is hosted by Evon Mendrin, CFP®, CSLP®, owner of Optometry Wealth Advisors, a financial planning firm just for optometrists nationwide. 

Every firm competing for talent is saying the same things. Great culture. Exciting projects. Competitive benefits. And candidates can't tell any of you apart. That's the problem James Ellis has built a career solving. In this episode, James breaks down what employer brand actually is (hint: not a campaign, not a vibe, not a careers page redesign) and how midsized companies can build a brand that wins talent without outspending bigger competitors. We get into why most employer brand work is theater, what candidates actually believe about your firm, and how to change what recruiters say and hiring managers reinforce. This one is for AEC firm leaders, TA and HR professionals, and anyone tired of posting jobs into the void and wondering why the right people never apply. About James Ellis: James Ellis is the founder of Employer Brand Labs, where he builds choosable employer brands for mid-market companies in 3 to 5 weeks. He's built employer brands at Webflow, Roku, ASICS, and Telecare over more than 13 years, and he's the bestselling author of Becoming Choosable and Talent Chooses You. Based in Chicago, James describes his stage presence as equal parts strategist and friendly arsonist. Find him at employerbrandlabs.com and on LinkedIn at linkedin.com/in/thewarfortalent. What We Cover: Introduction and James's background building employer brands at Webflow, Roku, and ASICS Why most companies don't have a hiring problem, they have a differentiation problem What "employer brand theater" looks like and why it fails How midsized firms can compete for talent without outspending the giants What it means to be a "choosable" employer How employer brand shows up in job posts, outreach, career sites, and interviews Why you can rent attention but you can't rent trust Where to find James + closing thoughts Key Takeaways: Employer brand is a system, not a campaign. It changes what candidates believe, what recruiters say, and what hiring managers reinforce. If your job posts could belong to any of your competitors, candidates have no reason to choose you. Midsized firms win talent through clarity and differentiation, not budget. You can't scale a business faster than you can hire the right people. Employer brand work should be usable Monday morning, not next quarter. Resources + Links: Employer Brand Labs: https://www.employerbrandlabs.com James on LinkedIn: http://linkedin.com/in/thewarfortalent Newsletter: https://employerbrandheadlines.com Books, videos, podcasts, and articles: http://www.EB-AF.com Becoming Choosable and Talent Chooses You by James Ellis  

This week on the Exciting & New podcast, Jason, Andy and Dana welcome Mike back on the show as they discuss the 1986 crime drama F/X.  In this frachise starter, a Crocodile Dundee clone is a special effects (F/X, get it?) expert, hired to fake the death of a mob informer, using the power of F/X.  But maybe he really killed him.  Or maybe the whole thing is a con.  There are a lot of twists and turns in this one, and then Tommy Boy's dad show up.  He should have been introduced much earlier in the film.  Anyway this was a very divided flick for the E&N team.  Listen to them argue over the merits (or possibly lack there of) of this movie.  Enjoy the podcast!!Jason, Andy and Dana will discuss a 1986 movie weekly, breaking down all the nonsense there within. The 3 hosts all work together and everyone else around them was getting really annoyed at all the movie talk, so they decided to annoy the world in podcast form.Check out previous seasons to hear them discuss 1982, 1983, 1984 & 1985 movies, as well as a full season of Love Boat episodes (if that is your thing). Plus one-off specials and a weekly mini "what are we watching" podcast.#jezoo74 #aegonzo1 #danacapoferri #exciting_new

Steve Adams joins Darragh McDonald to discuss the Cardinals signing JJ Wetherholt to a long-term extension, the Pirates acquiring Jacob Gonzalez from the White Sox to replace the injured Konnor Griffin, the great season the White Sox are having and the rationale for them to trade away assets in the middle of a playoff race, how the Marlins have put themselves in position to keep Sandy Alcantara and buy at the deadline, and if the Athletics will pivot to selling following their brutal past month. 

In this episode of the Building PA Podcast, co-hosts Chris Martin and Jon O'Brien welcome Ben Connors, the president of the General Building Contractors Association (GBCA), to discuss the current trends and challenges in the construction industry, particularly in the Philadelphia market.We kick off the episode with a warm introduction, highlighting the exciting atmosphere in Philadelphia as the city prepares for the World Cup and celebrates its 250th anniversary of democracy. Ben shares his insights on how these events are energizing the local economy and influencing construction trends.Diving into the construction landscape, Ben notes that the market is experiencing a downtrend, marking the third consecutive year of decreased activity. He explains that historical patterns suggest a potential bottoming out by 2026, with hopes for a rebound in 2027-2028. A significant focus of the conversation is on the rising demand for data centers in the region, which are driving construction activity, particularly in areas surrounding Philadelphia. Ben discusses the challenges posed by the overwhelming demand for power to support these data centers, which has doubled in recent years.As we explore the current projects and market trends, Ben highlights the shift away from commercial office space construction, largely due to the rise of remote work. He emphasizes the importance of specialized work in the industry, noting that contractors with expertise in this area are finding more opportunities. Exciting developments on the horizon include a new arena for the Philadelphia 76ers, a major investment from a Korean shipbuilder at the Navy Yard, and the transformation of the old Philadelphia gas refinery into the Bellwether District, an industrial park.We also discuss the challenges facing GBCA members, including increased competition and thin profit margins in a down market. Ben points out the ongoing struggle against commoditization in construction, particularly in the residential sector, where out-of-town developers are cutting costs.The conversation shifts to technology and the impact of AI on the construction industry. Ben shares how GBCA is embracing AI to enhance member engagement and improve safety outcomes. He highlights the growing interest in AI applications, from estimating to safety chatbots, and the potential for these technologies to revolutionize the industry.As we wrap up the episode, Ben provides insights into ongoing projects in healthcare and education, including the expansion of Children's Hospital and the conversion of the historic Wanamaker building into mixed-use space. He emphasizes the importance of safety in construction and the value of union contractors in delivering high-quality work.This episode is packed with valuable information and insights into the evolving construction landscape in Philadelphia. We thank Ben for joining us and look forward to having him back in the future to continue the conversation.

Episode 675. Alice Cooper has always been the undisputed master of theatrical rock, but after seeing the new Alice Cooper & Criss Angel show, we think live rock entertainment just took a major step forward. In this episode of Three Sides of the Coin, we review the concert and discuss why this collaboration feels so fresh, exciting, and unlike anything else on the road today. From the incredible stage production and mind-bending illusions to Alice's timeless performance and the way the show reinvents the concert experience, we break down what works, what surprised us, and why this may be a glimpse into the future of live rock shows. If you're an Alice Cooper fan—or simply love seeing artists push creative boundaries—you won't want to miss this discussion. Three Sides of the Coin https://linktr.ee/ThreeSidesoftheCoin Three Sides of the Coin has moved to its own YouTube Channel, don't miss any future episodes click the link below and click SUBSCRIBE… so easy! Subscribe –    / @threesidesofthecoinkisspodcast   Press requests please contact Michael Brandvold at www.michaelbrandvold.com Since launching in 2012 Three Sides of the Coin has been viewed or listened to over 6,000,000 times. Three Sides of the Coin has been joined by special guests including former KISS lead guitarist Bruce Kulick, Eddie Trunk, AEW Superstar and lead singer of Fozzy Chris Jericho, Angel lead guitarist Punky Meadows, Five Finger Death Punch guitarist Jason Hook, Vinnie Vincent Invasion and Slaughter lead singer Mark Slaughter, Twisted Sister's Dee Snider, comedian Craig Gass, KISS' former business manager Chris Lendt, the Black Veil Brides’ Andy Biersack, Frank Munoz associate producer for Ace Frehley’s Anomaly album, award winning songwriter Adam Mitchell, Ed Kanon (Peter Criss’ drum tech), Kevin Valentine (drummer on KISS’ Psycho Circus album). Three Sides of the Coin was picked (October 2013) as a ‘What’s Hot’ podcast by Apple’s iTunes. In the early ’90s, Michael Brandvold launched the fifth ever website on the Internet devoted to KISS, KISS Otaku. He built, launched and maintained Kissonline.com (KISS’ official web presence). He now owns Michael Brandvold Marketing, providing marketing services and digital strategy to musicians. Tommy Sommers spent 15 years on the record show circuit collecting, trading and selling memorabilia / Kiss merchandise. He is now a successful residential Real Estate agent in the Minneapolis / St. Paul area. Tommy has also produced a KISS song For The Oddfathers and is the owner of Rock Steady Digital Photography. Mark Cicchini, is a world renown KISS collector. KISS have used parts of Mark's vast KISS collection for audio, video & print materials including their book NOTHIN TO LOSE, CD re release of the LOVE GUN album & the VH1 Ultimate Album KISS ALIVE! special as well as many other KISS projects. His wife also makes a mean meatloaf!!! It’s only our opinion… it’s neither right nor wrong. Three Sides of the Coin Radio: www.threesidesofthecoinradio.com Facebook: facebook.com/threesidesofthecoin Twitter: twitter.com/threesidescoin Spotify: spotify.threesidesofthecoin.com YouTube: youtube.threesidesofthecoin.com iHeartRadio: iheartradio.threesidesofthecoin.com Spreaker: spreaker.threesidesofthecoin.com iTunes: itunes.threesidesofthecoin.com TuneIn: tunein.threesidesofthecoin.com Stitcher Radio: stitcher.threesidesofthecoin.com SoundCloud: @michaelbrandvoldmarketing Web: threesidesofthecoin.com Merchandise: shop.threesidesofthecoin.com Three Sides Of The Coin is unofficial & unsanctioned and has no affiliation with the band KISS. MichaelBrandvold.com Three Sides of the Coin Monthly Option 1 : $1.99 USD – monthlyOption 2 : $5.00 USD – monthlyOption 3 : $9.99 USD – monthly If you would rather make a one time donation of any amount, please use the Donate button below.

Get all the reaction from both All-Ireland Senior Football Championship Semi-Finals from Croke Park over the weekend as Mayo swept past Louth to secure their place in the final and Dublin felt hard done by as they lost out to a battling Kerry who hope to go back to back at Croke Park in 2 weeks time.You will hear firstly from Mayo manager Andy Moran and later Louth manager Gavin Devlin following Saturday's semi-final. Then you will hear from Kerry manager Jack O'Connor and finally Dublin manager Ger Brennan following Sunday's semi-final.Football on Off The Ball with Movember

Spurs Chat: Discussing all Things Tottenham Hotspur: Hosted by Chris Cowlin: The Daily Tottenham/Spurs Podcast Hosted on Acast. See acast.com/privacy for more information.

7.10.26, JP and Steve Czaban ask callers how excited they are about the Wizards' future after seeing AJ Dybantsa's impressive debut in NBA Summer League.

Friday's 7am hour of Mac & Cube kicked off with the guys being excited for SEC Media Days, even though we often feel like nothing happens; and then later, we go over the Top-10 CFB coaches and make reasons for and against their positions. "McElroy & Cubelic In The Morning" airs 7am-10am weekdays on WJOX-94.5!!See omnystudio.com/listener for privacy information.

Warriors guard Brandin Podziemski joins Grandi & Dibs to chat about the Golden State Valkyries hot start, Yaxel Lendeborg's strong Summer League showing and possibly playing with LeBron James

The CEO and founder of Evo3 Marketing discusses brand engagement through activations and events.

Sona Asset Management is looking to expand its business in asset-based finance and significant risk transfers as public and private debt markets converge. “The thing that excites us the most is the scope for growth in ABF markets here in Europe,” Henrik Johnsson, the London-based hedge fund’s chief executive officer, tells Bloomberg News’ James Crombie and Bloomberg Intelligence’s Aidan Cheslin in the latest Credit Edge podcast. “We really like SRTs, although spreads have obviously come in a lot over the last couple of years,” Johnsson adds. They also discuss how to short corporate debt, software-loan distress, secondary sales of private credit assets and investing in the AI boom.See omnystudio.com/listener for privacy information.

Cam Inman of The Bay Area News Group joins the boys for a wide-ranging conversation that covers everything from the World Cup to the Giants and 49ers. Cam shares his thoughts on the World Cup, including the excitement of the event and the challenges of covering it as a journalist. He also discusses the Giants and 49ers, offering his analysis on the teams' performances and the challenges they face.See omnystudio.com/listener for privacy information.

This week on the Exciting & New podcast, Jason, Andy and Dana welcome Shamus back on the show as they discuss the 1986 BMX-citing flick Rad.  This movie stars a pre-felon Aunt Becky and a post-Spicoli Mr Hand, along with a whole bunch of nobodies on BMX bikes (Oh, Rocky's wife makes an appearance, apparently paying the price for being married to the producer) .  This movie has it all.  A bike trick montage, a paper delivery montage, a dance montage, a dance-bike montage, and a racing montage, along with open credits shot over bike tricks and end credits shot over bike tricks.  Yup.  That's the whole movie.  It's Hot Dog! The Movie, set to bikes.  Enjoy the podcast!Jason, Andy and Dana will discuss a 1986 movie weekly, breaking down all the nonsense there within. The 3 hosts all work together and everyone else around them was getting really annoyed at all the movie talk, so they decided to annoy the world in podcast form.Check out previous seasons to hear them discuss 1982, 1983, 1984 & 1985 movies, as well as a full season of Love Boat episodes (if that is your thing). Plus one-off specials and a weekly mini "what are we watching" podcast.#jezoo74 #aegonzo1 #danacapoferri #exciting_new

In this episode, Brandon jumps on the mic again for the first time in a year. He shares why he left, where he's been and what he's been building since: an invite-only, community-owned platform called Industree that he invites the listeners to take part in. He also shares a recent angelic synchronicity story that has him feeling very optimystic about the Industree launch. Join the community-owned ecosystem Industree with referral code PHEAD at TheIndustree.com    Follow the journey on Instagram where Brandon will be sharing often Instagram.com/0ptimystic   Register for the Industree Webinar July 9th at 5pm PDT at tinyurl.com/industreejuly9    Checkout the uncanny Industree Origin Story at industr.ee/origin-story

Want to Start or Grow a Successful Business? Schedule a FREE 13-Point Assessment with Clay Clark Today At: www.ThrivetimeShow.com   Join Clay Clark's Thrivetime Show Business Workshop!!! Learn Branding, Marketing, SEO, Sales, Workflow Design, Accounting & More. **Request Tickets & See Testimonials At: www.ThrivetimeShow.com  **Request Tickets Via Text At (918) 851-0102   See the Thousands of Success Stories and Millionaires That Clay Clark Has Helped to Produce HERE: https://www.thrivetimeshow.com/testimonials/ Download A Millionaire's Guide to Become Sustainably Rich: A Step-by-Step Guide to Become a Successful Money-Generating and Time-Freedom Creating Business HERE: www.ThrivetimeShow.com/Millionaire   See Thousands of Case Studies Today HERE: www.thrivetimeshow.com/does-it-work/  

Exciting news for Canadians visiting Europe or Europeans visiting Canada, WestJet and Icelandair signed a reciprocal codeshare agreement in June. Meggan shares what this means for you and what new destinations could be on the table!Support the Travel Mug Podcast by buying us a coffee! You'll make our day & you'll get access to fun stuff like bloopers and extra content.We have Merch! Shop the Travel Mug Podcast Store Check out our fav items here: Our Favourite Travel ProductsGRAB OUR MASTER PACKING LIST HERE*****************************************We are travel enthusiasts who do not claim to be professionals! Instead, we are two Halifax, NS natives with travel blogs who somehow found one another on the internet, and now, we have a podcast!!Join us every week as we talk about our favourite destinations, travel tips, travel fails, and all things travel!We have a big passion for travelling and talking about travel, so we hope you will listen and join the conversation.You can find us here:Our WebsiteFacebookInstagramJenn's Travel Blog Jenn's YouTube channelDisclaimer: All episodes are based on our opinions and experiences. Always do your research and make travel plans based on your budget and comfort levels.Support the show

Matt and Paddy assess Jordan Pickford's stunning performance for England at Azteca Stadium. We then turn our focus to the signing of Tyrique George and what it says about Everton's transfer plans.

Get all the reaction from both All-Ireland Senior Hurling Championship Semi-Finals from the weekend, with Galway and Limerick booking their place in the All-Ireland final which is just 13 days away.You will hear from Limerick manager John Kiely, Clare manager Brian Lohan, Galway manager Micheal Donoghue and finally Ben O'Connor as they all reflect on wins or losses at an instant classic weekend at GAA HQ.Hurling on Off The Ball with Applegreen

Welcome back friends. Thanks for listening. On today's episode, I briefly check in with an update in regards to Searching for Meaning my new collaboration with my spiritual community, The United Church of Big Rapids.

Most men are not living their lives. They are surviving them. Caught in the rat trap. Consumed by the next deal, the next KPI, the next report. And by the time they get home, the family gets the leftovers. This episode is a Sunday morning reality check — recorded on a mill-pond-still sea with 30 degrees of sun on the way — about what it actually means to build a life you wake up and like living. Inside this episode: •Why so many high-performing men are in survival mode without even realising it •The difference between a busy life and an aligned life — and how to tell which one you are living •Why I started taking Fridays off — and why it changed everything •What my five-year-old daughter taught me about how to actually live •Why an exciting life is not about jet skis and fast cars — it is about feeling connected to the direction you are going •The three things blocking you from the life you want: toxic habits, limiting beliefs, and the negative narratives you tell yourself •The architect plans exercise: how to design the life you actually want on paper •Why peace, simplicity, contentment, and calm are the four keywords I am building my life around •Why you keep reverting to the old ways — and how to stop You have time to do this. You just need to stop being just fucking busy.   Book your clarity call https://consulting.boardmanjames.com/clarity-call-booking-form

Tomorrow is the 250th anniversary of America, which is a pretty big deal. It's no 200, but not all of us got to experience that one. Here's to 300, right? And speaking of things that are sure to last 300 years, Taylor Swift and Travis Kelce are getting married today. If you want, you can sit there and watch a live stream of their guests arriving. Exciting stuff. Not as exciting as eating 70ish hot dogs in ten minutes though. Oh, sorry, did I say exciting? I meant disgusting.And yes, "overmorrow" is a word. It means "the day after tomorrow". Neat, huh?Official discussion link: https://completedisaster.live/2026/07/03/july-3rd-2026/

God didn't design marriage to be depressing and unfulfilling. However, because marriage is between two imperfect people, marriage can easily become unfun and difficult. In today's message, I am presenting a six-month process to turn a marriage from drudgery to happiness and excitement. This is important because there is a connection between having a happy marriage and succeeding in a God-given calling. __________ Peter 3:7 KJV, 1 Corinthians 7:33–34 KJV, Proverbs 15:1 KJV, Galatians 6:7 KJV, 1 Peter 3:1 KJV, Proverbs 25:21–22 KJV __________ Partner with Us: https://churchforentrepreneurs.com/partner Connect with Us: https://churchforentrepreneurs.com __________    

Daryl and Coach Rizz talk about all of the positives they saw from the Guardians in their walk off win over the White Sox.

Exciting announcements this week including the second set of Legions Con 2026 exclusives and the date for the new Cosmic Legions wave announcement. Plus theres also Cosmic Legions SDCC drop Saint Demmyan and a snake figure featuring never seen before unarmoured parts. Support us! https://www.patreon.com/TheEuroLegionsPodcasthttps://linktr.ee/theeurolegionspodcastOur favourite retailer: https://figurenlager.de/collections/four-horsemen-studiosOur favourite custom parts: https://calvocustomcreations.com/mythic legions toy collecting fantasy cosmic legions

Can one tiny flower soften dry skin, soothe swollen tissues, calm the heart, and even inspire a little everyday magic?Violets may be small, but they have an astonishing amount to offer. In this episode, I sit down with herbalist Lindsey Feldpausch to celebrate one of our shared favorite plants: violet (Viola spp.). Together, we explore why this humble spring flower deserves far more attention—not only for its beauty, but for its remarkable ability to soothe dry tissues, support the lymphatic system, nourish the body, and gently soften both physical and emotional tension.Along the way, Lindsey shares stories from her own herbal journey, explains the fascinating diversity within the Viola genus, and reveals why she considers violet a true kindred spirit. We also dive into the chemistry behind violet's elusive fragrance, explore surprising new research, and, of course, spend plenty of time delighting in the simple joy of getting down on the ground with a patch of blooming violets.During our conversation, Lindsey also shares all about her gorgeous Violet Elixir—a beautiful (and magically color-changing!) spring preparation that's every bit as enchanting as the flowers themselves. Be sure to download your beautifully illustrated recipe card here.By the end of this episode, you'll know:► The fascinating reason violet's fragrance seems to disappear almost as quickly as you notice it► Why violet can be especially helpful for new mothers►The simple trick that can make all the difference in your violet salve► Exciting new scientific research that has herbalists paying even closer attention to this familiar plant► The hidden botanical secret that helps violets spread so beautifully in the garden► and so much more…For those of you who don't know her, Lindsey Feldpausch, RH(AHG) is a clinical herbalist, educator, and Assistant Director at the Herbal Academy. With over 15 years of experience in the field of herbalism, Lindsey's work has been focused on herbal education and clinical herbal practice, teaching for online and in-person herb programs, as well as at a variety of conferences, while maintaining a private practice of her own.As an herbalist, Lindsey's goal is to connect plants with the humans who need them. She believes in our innate ability to engage with the power of plants, and one of her life's intentions is to kindle this belief in others. Lindsey's herbal works have coalesced into her business, Plant Matters, where she offers herbal education, consulting, and handcrafted herbal products.After this episode, you may find yourself slowing down the next time you pass a patch of violets—and discovering just how extraordinary these tiny flowers really are.----Get full show notes, transcript, and more information at: herbswithrosaleepodcast.comWould you prefer watching this episode? If so, click here for the video.You can find Lindsey at PlantMatters.org.You can find Lindsey's course, Holistic Approaches for Tick-Borne Diseases, here.For more behind-the-scenes of this podcast, follow @rosaleedelaforet on Instagram!Working successfully with herbs requires three essential skills. Get introduced to them by taking my free herbal jumpstart course when you sign up for my newsletter.If you enjoy the Herbs with Rosalee podcast, we could use your support! Please consider leaving a 5-star rating and review and sharing the show with someone who needs to hear it!On the podcast, we explore the many ways plants heal, as food, as medicine, and through nature connection. Each week, I focus on a single seasonal plant and share trusted herbal knowledge so that you can get the best results when using herbs for your health.Learn more about Herbs with Rosalee at herbswithrosalee.com.----Rosalee is an herbalist and author of the bestselling book Alchemy of Herbs: Transform Everyday Ingredients Into Foods & Remedies That Heal and co-author of the bestselling book Wild Remedies: How to Forage Healing Foods and Craft Your Own Herbal Medicine. She's a registered herbalist with the American Herbalists Guild and teaches many popular online courses. Read about how Rosalee went from having a terminal illness to being a bestselling author in her full story here.

In ‘ID Fund', Meghan McGowan and her husband Joe built a platform that gave their investors seamless access to exclusive — and lucrative — private investment opportunities. Now, with their new firm, Barramundi, they hope to build on that previous success by leveraging new technology, and expanding their total addressable market.Meghan is the Founder and CEO of Barramundi, a private markets and pre-IPO investment firm. Under her leadership, the company has grown to roughly 1.5 billion in assets under management, with more than five hundred million invested across the companies, and they are defining the next era of the economy, from AI infrastructure to drone technology and digital finance.Meghan joins us to discuss her atypical career path from wine futures to founding Barramundi, and the incredible opportunities they're creating for investors.Highlights:From wine to private markets (2:41)Coming up with a better way to invest (7:20)Investment opportunities (11:09)Barramundi vs. ID Fund (14:02)Leveraging Technology (16:38) 50k Minimum (17:50)Investing at Inflection Points (18:53)Marriage and Business (22:29)5-year Outlook (25:05)  Links:Barramundi WebsiteICR LinkedInICR TwitterICR Website Feedback:If you have questions about the show, or have a topic in mind you'd like discussed in future episodes, email our producer, joe@lowerstreet.co

Dan Bardell and Dan Rolinson get together for Wednesday club, where they discuss an array of topics, including Emi Martinez's potential replacements Zion Suzuki and Guillaume Restes. Today's video is brought to you by Oxford Natural — Optimum Day & Night. Visit https://oxfordnatural.com/1874 to find out more and get 70% off your subscription.

This episode has a fun personal twist: There's a counterfactual world where I was employee #1 at Genesis Molecular AI, the company behind today's episode. A certain introduction happened a few weeks too late and I had already happily signed at Atomwise, another ML-for-drug-discovery startup. Same problem, different company. I was certain ML was going to transform small molecule drug discovery. Early results were underwhelming. Useful at times, but nowhere near revolutionary. In the last year I've seen signs that ML is finally ready to deliver on my convictions from a decade ago. Genesis is one of the places that might have finally cracked this problem. I was super excited to come full circle and catch up with co-founder Evan Feinberg and CTO Sergey Edunov.If you are at all interested in small molecule drug discovery, we think you will find this fascinating!In our nearly two hour chat we cover:* What is small molecule drug discovery, and why is it hard* Structure prediction as a hotbed of innovation in AI algorithms* How advances in AI elsewhere have enabled stepwise improvements in predictive power* How the community benchmarks are essentially calling AI slop good enough* The Genesis flagship model (PEARL) can routinely hit a threshold that is necessary for real-world applications* New agentic workflows enabled by these highly accurate modelsRead on for more, and also some personal thoughts on the future at the end.The coolest diffusion research is happening at GenesisSergey Edunov came to Genesis from Meta where he led Llama 2 training and Llama 3 pretraining. Sergey was a former physicist who thought he was done with physics after many years of training LLMs. Then, he discovered Genesis, and was blown away with all the novel architecture work they've been developing.It probably surprises no one that modern LLM research has not resulted in fundamentally novel or exciting updates in architectures since almost the advent of the transformer — the entire field is using variants on the same idea that came out in the original “Attention is all you need” paper. Sure, some were quite useful (mixture-of-experts in particular allowed for the massive model paradigm we're at today), but there was very little conceptually exciting.“We sort of had to wait for the right primitive to get created, and that turned out to be diffusion… Actually, some of the most innovative diffusion research that's happening in our field is happening in 3D structure prediction right now.” — Evan FeinbergThe field of 3D structure prediction on the other hand has been a hotbed of research. Genesis' recent model PEARL (Place Every Atom at the Right Location) is able to understand protein flexibility, and model not just where the ligand goes, but also make small adjustments of the protein so that the two fit better than either alone. The field knew this was missing for a long time, but it was really hard to model until now.Agentic DiscoveryWhat makes this problem so hard? As Sergey points out, there are 10^60 possible drug-like small molecules. You'll never be able to search them all, and trying to find the good ones is something like finding a needle in a haystack — except everything except your needle is dangerous.“There are 10 to the 60 drug-like small molecules in the universe… it's like finding a needle in a haystack, where everything except your needle is very, very dangerous.” — Sergey Edunov“Or finding hay in a needle stack might be a more apt analogy.” — Evan FeinbergTrying to solve the multi-parameter optimization problem is even worse. What makes a strong binder and a molecule with good “ADMET Properties” are oftentimes at tension with each other. For example, a good binder is likely greasy, but a greasy molecule is likely insoluble so it won't enter the bloodstream and get to where it needs to go!Genesis' advances in generative AI have now pushed them beyond the threshold where they believe agentic drug discovery loops are finally possible. We all remember the early days of LLMs. They were great chatbots but terrible agents, as small errors compounded rapidly into uselessness. As LLMs got better, the usefulness of agents rapidly improved. Evan and Sergey argue that their models at Genesis recently passed a similar threshold. Their internal agentic drug-discovery system (code named SAPPHIRE) can now iterate like a chemist: look at and reason about poses, form hypotheses, read literature, use internal tools, create candidates for the next iteration. Combining this with automated lab partnerships like the one Genesis has with Incyte, we're rapidly approaching a time of drug discovery agents running 24/7 making/testing new molecules. Exciting times!Benchmark crisis: Everyone's favorite benchmark is slopOne surprising point that isn't talked enough about: the academic field of “co-folding” has settled on a benchmark value of “2 Angstrom RMSD” as a metric for a “good pose”. Evan does not mince words: this threshold is just bad. Perhaps even deceptively bad. For many strong binders, there's a very clear pose, one that you can even directly resolve in the PDB electron density! And yet, with a 2Å RMSD threshold, you can get the pose quite wrong in ways that might even mislead a medicinal chemist. For example, flip around an aromatic ring, and everything looks reasonable, but you're no longer modeling the right interactions.Evan makes the strong claim that 1Å RMSD is really the threshold necessary to ensure the core of the molecule is sitting where it needs to be, and models all interactions.“If your model is sitting at 1.8, 1.9 Angstrom RMSD, that's slop, most likely.” — Evan FeinbergAs a simple example, he points out hydrogen bonds which are responsible for many of the most important interactions in protein-ligand systems. Hydrogen bonds only have a 0.6Å range to be valid! Clearly if you're accurately resolving all H-bonds, you generally have to be doing much better than the 2Å threshold.This is clearly a hard-fought lesson for Evan and Genesis. In their opinion, the community is stuck on these benchmarks because academics developing methods were not users. Evan does see signs of life, with the use of new metrics such as lDDT for co-folding. Hopefully soon the community can agree that “1.8Å RMSD is slop”, and start hill climbing on this much harder task.For a more thorough exploration of the weaknesses in conventional benchmarks, see the PEARL technical report.PEARL tops OpenBindWhich makes what happened next all the more striking. Near the end of the podcast, we talked about a recent “proof-is-in-the-pudding” moment for Genesis — evaluating their PEARL model on a recently released OpenBind benchmark. This benchmark featured 802 never before seen co-complexes on a target protein EV-A71. This target seems almost custom-chosen to give most classical docking methods a problem. When a ligand binds to the main binding site, the protein moves around to close off the path the ligand used to enter the binding pocket. This process, known as “induced fit” is notoriously hard for traditional methods to model. The tradeoff is easy to understand: treating the protein as a static structure, it becomes difficult to place a ligand in a binding pocket. Treat the protein as dynamic, and now you have to simulate complicated processes that take a long time to resolve.PEARL was able to model the induced fit of the ligand without running long MD simulations. Across the different evaluation metrics, PEARL came out not just ahead, but oftentimes well ahead of any public model. A truly impressive result.“Where PEARL was exceptionally good is figuring out how to move this loop. We are basically correct for every single pose.” — Sergey EdunovEven more exciting, this was done without any fine-tuning, or using any data on the target or homologous targets — the template PDB was released after PEARL's training cutoff.Where does co-folding go now?As someone who has followed or participated in ML techniques for protein-ligand interactions for almost a decade, I was genuinely impressed with the results that Genesis has released recently. This has been many years in development, and I'm sure Evan and the team had many sleepless nights trying to get to this point. I also think other teams are making similar progress — both Isomorphic and Deep Origin have released results that seem spiritually similar and combine computation, wetlab data, ML, to achieve genuine predictive power that seemed impossible a decade ago. Sadly, all of the above are closed source so there's no way to honestly compare them. Looking at the results I think there might be a time in the not so distant future where we can consider protein-ligand binding “solved”.I sincerely hope that the academic community can take inspiration from these developments. Once you know something can be done, it's much easier to execute. Still, I believe that the key enabler in all of the above was the tight integration of ML, large-scale computation, and real-world drug discovery applications. Sadly academia is just not structured in a way that makes such a development easy.With those parting thoughts, we hope you give the podcast a listen! This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.latent.space/subscribe

This week on the Exciting & New podcast, Jason, Andy and Dana ride solo as they discuss the 1986 kid adventure movie SpaceCamp.  In this "whoops, we launched a space shuttleby mistake" adventure movie, Mrs. Speilberg, Mrs. Travolta and Mrs. McFly are "kids" at SpaceCamp where a lot of nonsense ensues.  An up and coming Leaf Phoenix is there, along with Lamar from Nerds and Joshua from Friends.  John Williams mails in the score for ths one.  There seemed to be a lot of promise in this one, but just like visiting the actual NASA facility, they take space travel and make it really boring.  Enjoy the podcast!!Jason, Andy and Dana will discuss a 1986 movie weekly, breaking down all the nonsense there within. The 3 hosts all work together and everyone else around them was getting really annoyed at all the movie talk, so they decided to annoy the world in podcast form.Check out previous seasons to hear them discuss 1982, 1983, 1984 & 1985 movies, as well as a full season of Love Boat episodes (if that is your thing). Plus one-off specials and a weekly mini "what are we watching" podcast.#jezoo74 #aegonzo1 #danacapoferri #exciting_new

The Flattest State of Comics - EP. 1: Welcome to the Flattest State (Hope you survive the experience!) Watch the video version of this show on the Fandom Podcast Network You Tube Channel: https://www.youtube.com/live/KLsrNkXRpO8?si=a4-CRWUOkj8yIO1Z Welcome to Episode 1 of The Flattest State of Comics Podcast, in this EXCITING first episode we will kick things off by introducing all of you to all of us (get to know The Hosts of the FSC Podcast) followed by some SPOILER-FREE thoughts on the new Supergirl film. We will also be discussing each of our FIRE COMIC COVER OF THE MONTH and our IMPACT READ OF THE MONTH (for the month of June). PLUS sooo many more great segments that you will have to tune in to see!! #FandomPodcastNetwork #FlattestStateOfComics #ComicBookPodcast #Supergirl #FloridaComicCollector #MarvelComics #DCComics #ImageComics #DarkhorseComics #Independentcomics #Supportyourlocalcomicshop Flattest State of Comics @flatteststateofcomics (IG) Steven A. Brown @Comic_Ronin (IG) Spencer @TheStokedNerd (IG) Austin @TheRetroCorner_ (IG) Find all that is happening on the Fandom Podcast Network by visiting our Linktree site with direct links to our shows and social media. https://linktr.ee/fandompodcastnetwork

You can help us celebrate 10 years of Be Here Now Network and support the next chapter of Ram Dass Here and Now by donating to our 10th anniversary fundraiser. Exciting news! Dollar-for-dollar gift matching has been extended to match the first $60k in donations through June 30. Learn more and give here: BHNN 10th Birthday FundraiserWith his classic combination of heart and humor, Ram Dass guides us through an exploration of being on other planes of reality and getting comfortable with having nowhere to stand.Ram Dass Here & Now is brought to you by BetterHelp. Give online therapy a try at betterhelp.com/ramdass and get on your way to being your best self.This episode of Here and Now is from the first part of a talk Ram Dass gave at the LA Whole Life Expo on February 18, 1989. Check back soon for the conclusion of this lecture.Ram Dass begins with the story of having a kidney stone, and the delight he felt in watching his consciousness flicker. Thus begins an exploration of consciousness and being on other planes of reality.With some classic stories and his unique humor, Ram Dass talks about what happens when we awaken and start to recognize these other planes. As we get more comfortable in these other planes of reality, it can be easy to lose our ground on this plane.In the end, we can't push away this plane because it doesn't feel as good as others. Ram Dass shares how he saw it wasn't about getting high, it was about getting free and being comfortable with having nowhere to stand. We must embrace our humanity along with our divinity. The Ram Dass community gathers regularly to engage in meaningful discussions about the podcast. We invite you to join us and share your curiosities, insights, and wisdom. Sign up for the General Fellowship to receive event invitations directly in your inbox.About Ram Dass:Ram Dass's spirit has been a guiding light for generations, carrying millions along on the journey. Ram Dass teaches that through the Bhakti practice of unconditional love, we can all connect with our true nature. Through these teachings, Ram Dass has shared a little piece of his guru, Maharaj-ji, with all who have listened to him. Learn more at ramdass.org.“You've had this as your basecamp. You go into these other planes, and then you come back, and you go in, and you come back, and you go in. And you start to get comfortable being in other planes of reality and functioning here.” – Ram DassSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Billions of state quarters disappeared from circulation...and that was exactly the plan. Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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Dr. Phil is heading to the Arctic — and it could change America's energy future forever. A team of American wildcatters just earned the rights to drill the first modern oil wells in Greenland's remote Jameson Land Basin — and they believe they're sitting on 13 billion barrels of untapped oil. Dr. Phil is going there to see it happen. This isn't just an adventure. It's a front-row seat to history. Global oil reserves are at their lowest point in decades — and the clock is ticking. In this episode, Dr. Phil sits down with Robert Price, CEO, and Larry G. Swets, Jr., Executive Chairman of Greenland Energy. Ice. Oil. High stakes. No guarantees. This episode is made possible with the support of our sponsors.Sponsored by HighLevel: If you own a small business, don't skip this. Reclaim your life. Automate your business. Transform your overwhelmed business into an automated powerhouse in just minutes. Summer of AI Is Here! Get 5 FREE AI Tools All Summer Long. Visit: https://DrPhil.com/Business and get your life back on track.Sponsored by: Get up to $20,000 in FREE Gold & Silver with a qualified purchase. Text ASKPHIL to 50505 or visit https://DrPhilgold.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Summer is all about having fun: long days, warm nights, and getting together with the people you love. Today's episode is your playbook for making that time you spend with people more exciting and meaningful.  Mel is joined by Priya Parker, one of the world's leading experts on human connection. Her book “The Art of Gathering” is the most renowned work on how to bring people together and create moments that feel joyful and unforgettable.  In this episode, she will teach you simple ways to create real connections and make the time you spend with others memorable and fun. Whether you're planning a gathering, a wedding, a shower, a party, a family dinner, a work meeting, or you just want to make new friends and feel less alone, this episode will change the way you connect with other people.  You'll learn: -The #1 conversation starter that makes people feel instantly connected to you -How to become the person everyone wants to be around - 7 ways to bring people together and create real connection -How to make any dinner, party, meeting, or family visit more meaningful -How to make family time less tense and more fun -How to build connections when you've moved somewhere new -Why “keeping the peace” can quietly damage relationships -How healthy conflict can bring you closer to the people you care about After today you will have the tools and simple steps to create better conversations, stronger friendships, and deeper family connections and have a whole lot more fun, starting today. For more resources related to today's episode, click here for the podcast episode page.  If you liked the episode, check out this one next: Do THIS Today to Reset Your Life, Energy, & Happiness Connect with Mel:     Order Mel's new product, Pure Genius Protein Get Mel's newsletter, packed with tools, coaching, and inspiration. Get Mel's #1 bestselling book, The Let Them Theory Watch the episodes on YouTube Follow Mel on Instagram  The Mel Robbins Podcast Instagram Mel's TikTok  Subscribe to SiriusXM Podcasts+ to listen to new episodes ad-free Disclaimer Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.