Podcasts about long term outcomes

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Outcomes of Targeted Volume Overload Management in Patients With Severe Aortic Stenosis.

Another positive digoxin trial, another classic coronary physiology study from Imperial College London (ORBITA-FIRE), news in hypertrophic cardiomyopathy, and TAVR done in the wrong patients are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Digoxin in Rheumatic Heart Disease Dig-RHD Trial https://jamanetwork.com/journals/jama/fullarticle/2848973 Safety and Efficacy of Digoxin: Meta-Analysis https://www.bmj.com/content/351/bmj.h4451.long DIGIT-HF Trial https://www.nejm.org/doi/full/10.1056/NEJMoa2415471 DIG Trial https://www.nejm.org/doi/full/10.1056/NEJM199702203360801 RADIANCE Trial https://www.nejm.org/doi/full/10.1056/NEJM199307013290101 II The Physiologic Threshold for Angina ORBITA-FIRE Trial https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.125.078738 III Prediction in Hypertrophic Cardiomyopathy Predictors of Long-Term Outcomes in HCM https://jamanetwork.com/journals/jama/fullarticle/2848800#250998713 IV TAVR Trends in Young Patients Temporal Trends in AVR for Aortic Stenosis in Patients < 65 https://www.ahajournals.org/doi/10.1161/CIRCINTERVENTIONS.126.016826 Wall Street Journal article https://www.wsj.com/health/healthcare/heart-valve-tavr-surgery-aorta-1e0eda70 You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

Curious if you qualify for TRT in Australia? We break down the real eligibility criteria, extensive blood work requirements, telehealth process, and what to expect long-term - from benefits to risks and ongoing monitoring.For more information, visit https://trtaustralia.com/trt-sydney/ TRT Australia City: Hurstville Address: 7–11 The Avenue Website: https://trtaustralia.com/

Send us Fan MailDr. Ward Rice, neonatologist and researcher within the Neonatal Research Network, presents two-year follow-up data from the landmark ACT NOW Eat Sleep Console trial — one of the largest multi-center randomized trials ever conducted on neonatal opioid withdrawal syndrome. He shares findings on neurodevelopmental and behavioral outcomes at two years of age in babies exposed to buprenorphine versus methadone in utero, explaining why the short-term advantages of buprenorphine did not translate into measurable differences at this time point — but why both groups still scored below population norms on Bayley testing, underscoring the ongoing developmental risk in this population. He also discusses why longer follow-up is planned, what a smaller four-year study suggests may still emerge, and why this research ultimately informs prenatal decision-making by obstetric colleagues just as much as neonatal care at the bedside.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

Send us Fan MailDr. Seetha Shankaran one of the pioneers of therapeutic hypothermia for hypoxic-ischemic encephalopathy (HIE) and longtime member of the NICHD Neonatal Research Network, reflects on a career devoted to preventing and treating neonatal brain injury. She discusses what neonatal MRI can and cannot tell us about long-term neurodevelopmental outcomes in infants with HIE, why a normal MRI does not equal a normal future, and how the pattern of brain injury on imaging should shape the counseling conversation with families. She closes with a message that no imaging study can replace: consistent, long-term follow-up remains the most important tool we have.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

LBCT: Long-term Outcomes of Women and Men Undergoing Self-Expanding Vs. Balloon Expandable Valves: A Sex-specific Analysis Of The SOLVE-TAVI Trial

There's no such thing as a "square deal" anymore. This week's Spotlight explores how brokers are adapting to a tougher commercial lending market using faster, more flexible non-bank solutions. Commercial lending has shifted – and brokers are right at the centre of it. As bank appetite tightens, costs rise, and deals become more complex, the old playbook isn't holding up. What's replacing it is faster, more flexible, and more strategic non-bank funding. Broker Daily's Julian Barnes is joined by Michael Volkiene, general manager of loan origination and credit at Msquared Capital, to unpack how brokers are adapting and why non-bank lending is becoming a critical part of the solution. This isn't about replacing banks – it's about filling the gaps they leave behind using short-term capital to unlock opportunities, manage time pressure, and create a pathway back to traditional funding. And increasingly, brokers are doing exactly that. Here's what's driving the shift: Brokers are reshaping deals with short-term, flexible non-bank funding to bridge gaps and secure opportunities. Speed, certainty, and transparency are becoming critical as bank appetites shift. A more strategic, long-term approach is helping brokers retain clients and navigate complexity. In a market that's only getting tougher, the brokers who win won't just be the ones who find a lender – they'll be the ones who know how to structure the deal.

In this validating episode, Kayleigh is joined by Dr. James Jackson, an internationally recognized psychologist, neuropsychology specialist, and pioneer in post-intensive care syndrome (PICS). Together, they explore the often-overlooked reality of medical trauma and what true healing can look like after surviving critical illness.

Dr. Kenneth Ellebogen, Deputy Editor of JACC: Clinical Electrophysiology, discusses the long-term outcomes and safety of His-Purkinje conduction system pacing: a multicenter observational study in China.

Send us Fan MailIn this episode of Journal Club, Ben and Daphna review a pivotal paper from the Journal of Pediatrics led by the Pediatric Pulmonary Hypertension Network (PPHNet). The study explores invasive hemodynamic metrics and long-term outcomes in infants with BPD-associated pulmonary hypertension. Surprisingly, researchers found an almost equal distribution of pulmonary hypertension across mild, moderate, and severe BPD grades using the Jensen criteria. The hosts discuss the implications of these findings, questioning whether our traditional 36-week assessment timepoint is sufficient and if current grading criteria capture the true severity of pulmonary vascular disease in these vulnerable infants.----Pulmonary Hemodynamics and Long-Term Outcomes in Children with Pulmonary Hypertension-Associated Bronchopulmonary Dysplasia. Austin ED, Mullen MP, Avitabile CM, Krishnan US, Rosenzweig EB, Keller RL, Kinsella JP, Yung D, Steffes L, Bates A, Elia EG, Romer LH, McGrath-Morrow S, Bernier ML, Mandl KD, Raj JU, Sleeper LA, Abman SH; Pediatric Pulmonary Hypertension Network (PPHNet) Investigators.J Pediatr. 2026 Feb;289:114869. doi: 10.1016/j.jpeds.2025.114869. Epub 2025 Oct 24.Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below.Enjoy!

In this episode of Better Edge, Kevin C. Welch, MD, professor of Otolaryngology–Head and Neck Surgery at Northwestern Medicine, talks about his recent study that evaluated if endoscopic sinus surgery affects the long term risk of asthma and bronchiectasis in patients with chronic rhinosinusitis. Drawing from a large retrospective cohort with extended follow up, the study explored differences in outcomes by disease severity and nasal polyp status. The episode also highlights how these findings may inform clinical decision making and patient counseling in the management of refractory CRS.

This episode is a recording of a seminar held in Cambridge, New Zealand, featuring presentations from Professor Wayne McIlwraith and Dr. Leigh de Clifford, introduced by host Dr. Jason Lowe. If you wish to watch the full episode with slides, please refer to our YouTube channel.Professor Wayne McIlwraith, BVSc, PhD, DSc, FRCVS, DACVS, is a University Distinguished Professor at Colorado State University, founding director of the Orthopaedic Research Center, and namesake of the C. Wayne McIlwraith Translational Medicine Institute. A New Zealand native, he is a past president of both the American College of Veterinary Surgeons and the American Association of Equine Practitioners, an inductee into the International Equine Research Hall of Fame, and a recipient of the New Zealand Order of Merit for services to the veterinary industry. He has authored over 500 scientific publications and seven textbooks, and is recognized globally as a pioneer in equine arthroscopic surgery and joint disease research.Dr. Leigh de Clifford is the Technical Service Veterinarian for Contura Vet, with over 12 years of clinical and research experience using Arthramid across racing and equestrian disciplines worldwide.Dr. Jason Lowe, Chief Veterinary Officer for Contura Vet, opens the seminar with an overview of the Arthramid research timeline and the company's commitment to ongoing science across species.In this episode, you will learn:How 2.5% iPAAG integrates into the sub-intimal layer of the synovial membrane and why this mechanical pathway sets it apart from conventional drug-based therapiesThe significance of the FDA's classification of Arthramid as a veterinary medical device and what that distinction meansWhy synovitis is a major driver of osteoarthritis and how inflammation of the synovial membrane, not cartilage degradation alone, sits at the center of joint diseaseResults from the CSU carpal chip fragment model showing that Arthramid restored normal joint capsule elasticity in osteoarthritic joints, while untreated joints exhibited significantly increased stiffnessHow the macrophage-driven response to iPAAG is transient, peaking around 42 days and resolving by 90 days without fibrosis or granuloma formationEvidence of cartilage preservation in treated joints, including retained proteoglycan staining compared to controlsFindings from a retrospective analysis of 701 thoroughbred racehorses treated at a single practice in Melbourne over a seven-year period, including long-term safety data and career performance outcomes in 214 horsesWhy multiple injections in a single joint showed no increase in adverse events and no detrimental impact on race starts or career lengthThe limitations of corticosteroids in racing, including increased fracture hazard ratios after repeated use and tightening regulatory environmentsWhether you are a veterinarian looking for the latest research on iPAAG or a horse owner wanting to understand the science behind this treatment, this episode offers a comprehensive look at the evidence supporting Arthramid in equine joint health.Subscribe and share with your colleagues so you never miss an episode.Learn more at arthramid.com

Today, we're diving into a paper that reviews the long-term outcomes following arthroscopic Bankart repair and challenges some of the historical narratives around this procedure.The study that we are reviewing today is titled “Long-term Outcomes of a Contemporary Arthroscopic Bankart Repair Technique in Patients With Traumatic Anterior Shoulder Instability: A Minimum 10-Year Follow-up.” This is a minimum 10-year follow-up study looking at modern arthroscopic Bankart techniques using at least three anchors — and it asks: Are recurrence rates still as high as we've been taught?

In this new episode of Speaking of Surgonc, Dr. Rick Greene & Dr. Elena Panetti discuss the article: Short- and Long-Term Outcomes After Hepatectomy in Patients Receiving Triplet Versus Doublet Preoperative Chemotherapy for Colorectal Liver Metastases, from the January 2026 issue of the Annals of Surgical Oncology.

Dr. Lauren Colenso-Semple, PhD, is an expert in the science of strength and muscle building and nutrition. She explains the most effective resistance and cardiovascular training programs for women and if and how those programs should differ from those followed by men. She explains program design options, exercise selection, sets, repetition ranges, rest periods, if you need to train to failure and much more. We discuss the relevance of menstrual cycles, (peri)menopause, birth control, body frame differences, as well as best practices for nutrition, hormone replacement and supplementation. Throughout the episode Dr. Lauren Colenso-Semple dispels common myths about women's fitness and nutrition such as the impact of fasting, cortisol, weight vests and more. This episode provides a masterclass in the best science-supported fitness and nutrition programs for women and for men. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman Eight Sleep: https://eightsleep.com/huberman Rorra: https://rorra.com/huberman Function: https://functionhealth.com/huberman Timestamps (00:00:00) Lauren Colenso-Semple (00:02:43) Muscle in Men vs Women; Testosterone; Individual Variation (00:08:07) Sponsors: Joovv & Eight Sleep (00:10:45) Testosterone & Women; Resistance Training; Young Girls (00:17:46) Tool: Beginner Resistance Training for Women; Frequency & Goals (00:20:58) Tools: Weekly Full-Body Workouts, Work Sets, Rest Intervals; Time Efficiency (00:28:43) Forced Reps, Drop Sets; Rate of Movement; Partial Reps (00:33:19) Tool: Repetition Ranges; Technique; Vary Rep Ranges? (00:39:37) Sponsor: AG1 (00:40:28) High Reps & Injury, Technique & Warm-Ups (00:44:25) Cardiovascular Exercise, Interference Effect?; Walking, High Intensity (00:52:43) Menstrual Cycle, Hormones & Training; Overcoming Internal Resistance (00:56:54) Training & Body Composition; Tool: Slow Progression; Menstrual Cycle (01:02:45) Sponsor: Rorra (01:03:59) Hormone Contraception & Adaptations; Perimenopause, Menopause (01:09:01) Age-Related Muscle Loss, Nervous System, Tool: Machines & Group Fitness (01:14:57) Menstrual Cycle & Physical Activity; Nutrition (01:17:50) Pilates, Genes, Tool: Resistance Training to Offset Age-Related Muscle Loss (01:26:25) Ectomorph, Mesomorph or Endomorph? (01:28:55) Sponsor: Function (01:30:42) Train Fasted?, Caffeine, Preworkout & Postworkout Nutrition (01:38:29) Protein, Resistance Training & Timing (01:40:12) Creatine Supplements, Gummies, Dose, Brain Health Benefits? (01:45:44) Individual Experience; Skepticism & Science, Menopause & Body Composition (01:54:52) Cortisol & Women, Stress & Diet, Cushing Syndrome (02:00:17) Overtraining?, Sleep Disruptions, Energy & Training Time (02:04:07) Menopause Symptoms & Hormone Therapy, Testosterone (02:09:22) Women Differences in Diet & Training?; Exercise Science Studies (02:16:19) Lauren's Training Schedule, Mobility Work (02:19:35) Hormone Therapy & Long-Term Outcomes; Deliberate Cold Exposure (02:23:06) Zone 2 Cardio; Weighted Vest; Balance Training; Ab Exercises; Recovery (02:29:26) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

The management of complex regional pain syndrome (CRPS) continues to challenge clinicians—especially when conservative and interventional strategies fall short. This episode of RAPM Focus, hosted by RAPM Editor and Social Media Editor Ryan D'Souza, MD, explores these challenges in managing CRPS with Daniël van der Spek, MD, and Frank Huygen, MD, PhD, FIPP, FFPMCAI, following the August 2025 publication of their original research paper, “Long-term outcomes of amputation in patients with complex regional pain syndrome (CRPS): a mixed-methods study.” In rare and severe cases, amputation has been proposed as a last resort intervention, but the topic remains completely controversial. How does one weigh the potential relief of unrelenting pain against the risk of further complications and disability from an amputation? This episode explores a fascinating, mixed-method study into the long-term outcomes of patients with CPRS undergoing limb amputation in hopes of pain relief, despite risks of residual pain or phantom limb pain. Dr. Daniël van der Spek is a medical doctor and PhD candidate at the Erasmus University Medical Center under the supervision of Professor Huygen his research focus is on CPRS with a particular emphasis on interventional pain management. Dr. Frank Huygen is an anesthesiologist and pain physician serving as the head of the Department of Pain Medicine at Erasmus University Medical Center, and has been a full professor since 2009. His expertise focuses on CPRS and neuromodulation. He leads multiple national and international research projects, and maintains close collaborations with CRPS patient organizations, in both the Netherlands and the United States. *The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice, and it is not intended to function as a substitute for a healthcare practitioner's judgement, patient care, or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others. Podcast and music produced by Dan Langa. Find us on X @RAPMOnline, LinkedIn @Regional Anesthesia & Pain Medicine, Facebook @Regional Anesthesia & Pain Medicine, and Instagram @RAPM_Online.

In today's VETgirl online veterinary continuing education podcast, we review a recent paper by Kurogochi et al entitled “Long-Term Outcomes of Mitral Valve Repair with Artificial Chordae and Annuloplasty for Myxomatous Mitral Valve Disease in Dogs”, published in the Journal of Veterinary Internal Medicine in 2025. Now, you're unlikely to be doing heart surgery on your myxomatous mitral valve disease (MMVD) patients, but this study is important for you to know about! After all, there ARE surgical options out there!

In today's VETgirl online veterinary continuing education podcast, we review a recent paper by Kurogochi et al entitled “Long-Term Outcomes of Mitral Valve Repair with Artificial Chordae and Annuloplasty for Myxomatous Mitral Valve Disease in Dogs”, published in the Journal of Veterinary Internal Medicine in 2025. Now, you're unlikely to be doing heart surgery on your myxomatous mitral valve disease (MMVD) patients, but this study is important for you to know about! After all, there ARE surgical options out there!

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Long-Term Outcomes: Beta-Blocker Use and Permanent Pacing in Patients With Heart Failure Preserved Ejection Fraction.

Is the open thoracotomy becoming outdated as robotic surgery and advanced ablation techniques take center stage in lung cancer treatment? In the final discussion of the 2025 NSCLC Creator Weekend™ series, our virtual tumor board of interventional radiologists and pulmonologists from leading medical institutions discuss recent surgical and interventional advancements in the treatment of lung cancer. --- This podcast is supported by an educational grant from Johnson & Johnson and Varian. --- SYNPOSIS The conversation covers the contemporary role of PET scans, endobronchial ultrasound (EBUS), mediastinal staging, and the importance of perioperative systemic therapy. The doctors explore surgical and non-surgical methods for treating lung cancer, including lymph node dissection, criteria for resection, and the advantages of minimally invasive approaches such as video-assisted thoracoscopic surgery (VATS) and robotic-assisted surgeries.A key focus of this episode is the decision-making process for treating multifocal lung cancers while preserving lung function, and the use of combined therapies like ablation and radiation. The episode concludes with a detailed case study illustrating the long-term management of a patient with multiple lung adenocarcinomas over several years, highlighting the multidisciplinary approach required in such complex scenarios. --- TIMESTAMPS 00:00 - Introduction10:07 - Patient Selection and Comorbid Conditions27:29 - Surgical Margins and Resection Strategies42:11 - Understanding Upstaging in Cancer Treatment53:27 - Technical and Clinical Resectability56:13 - Case Study: Managing Multifocal Lung Cancer01:11:41 - Long-Term Outcomes and Treatment Strategies --- RESOURCES CALGB 140503 Trialhttps://www.nejm.org/doi/full/10.1056/NEJMoa2212083 JCOG0802 Trialhttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02333-3/abstract

When should an antibiotic allergy actually be tested? In this episode of the BackTable ENT Podcast, guest host Dr. Basil Kahwash, an allergist and immunologist at Ohio ENT & Allergy, sits down with Dr. Cosby Stone, an allergist and immunologist at Vanderbilt University Medical Center, to discuss antibiotic allergies and how to distinguish true allergies from intolerances. --- SYNPOSIS Dr. Stone breaks down common misconceptions around antibiotic allergies, with a focus on penicillin and cephalosporins. The conversation explores how these allergies are evaluated, including when skin testing is appropriate, why inaccurate allergy labels matter, and how confirmed allergies should be managed long term. They also dive into more advanced topics such as drug desensitization, current research in the field, and where the future of drug allergy evaluation is headed. --- TIMESTAMPS 00:00 - Introduction 01:03 - Understanding Antibiotic Allergies07:28 - The Importance of Accurate Allergy Diagnosis10:55 - Key Questions for Diagnosing Allergies17:10 - Implementing Allergy Testing in Healthcare Settings19:06 - Identifying Severe Allergic Reactions26:31 - Interpreting Allergy Skin Testing Procedures33:17 - Penicillin and Cephalosporin Cross-Reactivity37:15 - Drug Desensitization: Indications and Process40:30 - Prognosis and Long-Term Outcomes of Drug Allergies47:22 - Conclusion and Final Thoughts --- RESOURCES Dr. Basil Kahwash https://www.ohioentandallergy.com/physicians/basil-kahwash-md/ Dr. Cosby Stonehttps://www.vanderbilthealth.com/doctors/stone-cosby

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning reflects on the most popular content of 2025 on CTSNet. Chapters 00:00 Intro 02:15 Top Interview 03:52 Top Webinar 05:23 Top Clinical Video 06:24 Top JANS Article 07:01 Top Video Series 08:02 Top Contributor 08:59 Top Cardiac Procedures 12:14 Top Podcasts 17:02 JANS 1, Doctor Story 21:28 JANS 2, Ex Vivo Heart Perfusion 22:41 JANS 3, PCI vs CABG 24:04 JANS 4, NEOpredict-Lung 25:29 2026 Plans He discusses the top interview, the most popular webinar, and reveals the leading CTSNet contributor of the year. He also highlights the most-read JANS article, the most viewed CTSNet series, the top clinical videos in cardiac surgery, and the leading podcast episodes of 2025 from both The Beat and The Atrium. Additionally, he shares key statistics about CTSNet, including website viewership, YouTube subscribers, and listener demographics.   Joel also highlights recent JANS articles on if ex vivo heart perfusion offsets ischemic penalties with six-hour or greater preservation in adult donation after brain death heart transplantation, an impactful article titled “This Man Saved My Life—I Live by His Example,” the long-term outcomes for women with chronic coronary artery disease after percutaneous coronary intervention vs coronary artery bypass grafting, and the long-term outcomes of preoperative nivolumab with or without relatlimab in patients with resectable non-small-cell lung cancer (NEOpredict-Lung).    In addition, Joel outlines CTSNet's goals and initiatives to look forward to in 2026. Before closing, he highlights upcoming events in CT surgery.    JANS Items Mentioned  1.)  Ex Vivo Heart Perfusion Offsets Ischemic Penalties With ≥6-Hour Preservation in Adult Donation-After-Brain-Death Heart Transplantation  2.) This Man Saved My Life—I Live by His Example  3.) Women With Chronic Coronary Artery Disease: Long-Term Outcomes After Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting  4.) Long-Term Outcomes of Preoperative Nivolumab With or Without Relatlimab in Patients With Resectable Non-Small-Cell Lung Cancer (NEOpredict-Lung)  CTSNet Content Mentioned  1.) CTSNet Summarized—Most Popular Content of 2025  2.) CTSNet Summarized—Most Popular Podcast Episodes of 2025  3.) CTSNet Summarized—Top Cardiac Procedure Videos of 2025   Other Items Mentioned  1.) All CTSNet Summarized Content   2.) 2025 CTSNet Recruitment Guide   3.) Career Center   4.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Summary This podcast episode features a comprehensive discussion with Dr. Ekama Carlson and Dr. Faranak Kamangar on the latest advancements in acne treatment, particularly focusing on energy-based devices and the innovative AvaClear laser. The speakers delve into the pathogenesis of acne, the effectiveness of various treatments, and the importance of patient selection for laser therapy. They also share insights from clinical trials and patient experiences, highlighting the transformative impact of these treatments on individuals suffering from acne. Takeaways - Acne affects 10% of the world's population, making it a significant dermatological issue. - Energy-based devices are becoming increasingly popular for managing acne. - Selecting the right patient for laser therapy is crucial for successful outcomes. - The Acne Laser Series protocol involves multiple treatments for optimal results. - AvaClear laser technology specifically targets sebaceous glands for effective acne treatment. - Clinical trials show promising results for the AvaClear laser in reducing inflammatory lesions. - Patient education about treatment expectations is essential for satisfaction. - Long-term outcomes of laser treatments can lead to significant improvements in skin health. - Innovations in dermatology are changing the landscape of acne treatment. - Combining treatments can enhance efficacy and patient satisfaction. Chapters 00:00 - Introduction to the Future of Dermatology Podcast 00:40 - Understanding Acne Pathogenesis and Treatments 01:52-  Energy-Based Devices for Acne Management 05:22 - Selecting Patients for Laser Therapy 06:40 - Acne Laser Series Protocol and Results 11:35 - Comparative Effectiveness of Treatments 15:05 - Innovations in Acne Treatment: The AvaClear Laser 19:18 - Clinical Trials and Efficacy of AvaClear 24:42 - Patient Experience and Long-Term Outcomes

A nationwide CTX study, a critical treatment window, and a conversation with the lead author. Dr Tanyel Zübarioğlu joins the JIMD Podcast to unpack the long-term impact of CDCA therapy and why timing matters more than ever. Long-Term Outcomes of Chenodeoxycholic Acid Therapy for Cerebrotendinous Xanthomatosis: A Nationwide Study on Prognostic Factors and Treatment Tanyel Zubarioglu, et al https://doi.org/10.1002/jimd.70069 Editorial Comment to Regulatory News Carla E. M. Hollak, Natalja Bouwhuis https://doi.org/10.1002/jimd.70071

Commentary by Dr. Jian'an Wang.

This week we speak with Ohio State ACHD fellow Andrew Freddo MD, PhD about a recent large single center study he conducted assessing the cardiovascular drugs that adult Fontan patients are taking and whether they might offer us insights into general well-being. Are there agents that are associated with worse outcomes? If so, is this a situation of the agent causing harm or is it a possible marker of illness? Are there agents associated with improved outcomes? These are amongst the questions reviewed with Dr. Freddo this week. DOI: 10.1016/j.jacadv.2025.102070

Commentary by Dr. Tong Liu.

Aaysha Cader, MD MSc, social media editor for JACC: Cardiovascular interventions and Josep Rodés-Cabau, MD, PhD discuss the Impact of Early Hemodynamic Valve Deterioration on Long-term Outcomes Following Transcatheter Aortic Valve Replacement, published in the October 27 issue of the journal.

Aaysha Cader, MD MSc, social media editor for JACC: Cardiovascular interventions and Christoph Ryffel, MD discuss the Long-term Outcomes of Patients with Moderate and Severe Aortic Stenosis According to Stages of Cardiac Damage, manucript published in the October 27 issue of the journal.

This week, Marc Ruel guest-hosts in this episode of Circulation on the Run as it features the annual Surgery Issue for Circulation. First, Marc is joined by author Duk-Hyun Kang as they discuss his article "Comparison of Long-Term Outcomes of Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation: A Propensity Analysis." Then Marc is joined by authors Enoch Akowuah and Janelle Wagnild as they discuss their article "Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial." For the episode transcript, visit: https://www.ahajournals.org/do/10.1161/podcast.20251027.193601

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Sex Differences in Cardiovascular Health Status and Long-Term Outcomes in a Primary Prevention Cohort.

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. Marc Pelletier, division chief of cardiac surgery for the Department of Surgery at Yale School of Medicine, about patient blood management. Chapters 00:00 Intro 01:45 EACTS 2025 07:19 JANS 1, HVD Management Guidelines 16:26 JANS 2, Low-Risk AVR Evidence 19:21 JANS 3, Warden Procedure Selection 20:36 JANS 4, Primary Repair of CAT 21:48 JANS 5, NEWTON-CABG Cardiolink-5 23:20 Video 1, Acute Aortic Syndrome 24:54 Video 2, Redo TVR Under Bypass 27:13 Video 3, Giant Tension Bulla 28:47 Dr. Pelletier Interview 34:25 Outro They delve into the Society of Thoracic Surgeons (STS) guidelines on patient blood management, along with key tips. They also explore preoperative optimization, provide an example, and discuss cell savers and reducing dead space during surgery. Additionally, they touch on postoperative transfusion and the importance of performing meticulous surgery.  Joel also highlights recent JANS articles on the 2025 ESC/EACTS guidelines for the management of valvular heart disease, low-risk aortic valve replacement at the crossroads of evidence, ideal age and weight for the Warden procedure in patients with partial anomalous pulmonary venous return, a systematic meta-analysis of short- and long-term outcomes of the primary repair of common arterial trunk, and an international, randomized, double-blind, placebo-controlled trial on the effect of Evolocumab on saphenous vein graft patency after coronary artery bypass surgery.  In addition, Joel explores the surgical treatment of acute aortic syndrome, a redo tricuspid valve replacement technique under right heart bypass for a previously repaired tricuspid valve, and thoracoscopic resection of a giant tension bulla. Before closing, Joel highlights upcoming events in CT surgery.    JANS Items Mentioned  1.) 2025 ESC/EACTS Guidelines for the Management of Valvular Heart Disease: Developed by the Task Force for the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)   2.) Low-Risk Aortic Valve Replacement at the Crossroads of Evidence  3.) Is There an Ideal Age or Weight for the Warden Procedure in Patients With Partial Anomalous Pulmonary Venous Return?  4.) Primary Repair of Common Arterial Trunk: A Systematic Meta-Analysis of Short- and Long-Term Outcomes  5.) Effect of Evolocumab on Saphenous Vein Graft Patency After Coronary Artery Bypass Surgery (NEWTON-CABG CardioLink-5): An International, Randomized, Double-Blind, Placebo-Controlled Trial  CTSNet Content Mentioned  1.) Surgical Treatment of Acute Aortic Syndrome   2.) Redo Tricuspid Valve Replacement Technique Under Right Heart Bypass for a Previously Repaired Tricuspid Valve   3.) Thoracoscopic Resection of a Giant Tension Bulla   Other Items Mentioned  1.) STS/SCA/AmSECT/SABM Update to the Clinical Practice Guidelines on Patient Blood Management  2.) Transcatheter vs Surgical Aortic Valve Replacement in Lower-Risk Patients: An Updated Meta-Analysis of Randomized Controlled Trials  3.) Perfecting TAVR Removal | Skills Sharpening With Vince Gaudiani  4.) Career Center   5.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Commentary by Dr.  Jian'an Wang.

Long-term Outcomes of the DanGer Shock Trial

In this episode we discuss new insights into the variability of long-term outcomes in classic galactosemia. Joining me are Nikki Smith, Olivia Garrett, and Judy Fridovich-Keil, who together explore how complications in cognitive, motor, and speech domains emerge, cluster, and vary in severity across patients. Their study highlights both patterns and unanswered questions, illustrating the challenges families face and the importance of refining prognostic tools. Patterns of Penetrance and Expressivity of Long-Term Outcomes in Classic Galactosemia Nicole H. Smith et al. https://doi.org/10.1002/jimd.70020

Despite advancements in surgical techniques, the recurrence rate of anterior cruciate ligament (ACL) rupture after reconstruction remains between 2% and 20%. An increased posterior tibial slope (PTS) is associated with higher ACL rupture and reconstruction failure rates.   In conclusion, ACW-HTO combined with ACL reconstruction shows promising long-term outcomes, significantly reducing PTS and improving knee stability and function with an acceptable complication rate.   Click here to read the article.

This week on The Beat, CTSNet Editor-in-Chief Joel Dunning speaks with Dr. Kenneth Liao, professor of surgery and chief of the Division of Cardiothoracic Transplantation and Circulatory Support at Baylor College of Medicine, about performing the world's first adult robotic heart surgery in the United States using a subxiphoid approach. Chapters 00:00 Intro 02:31 JANS 1, Endocarditis Guidelines 13:02 JANS 2, Hybrid vs Catheter 16:16 JANS 3, Full Sternotomy Trial 18:07 JANS 4, Buttressing the BA 19:05 JANS 5, Intraspinal Vasc Perf 20:15 Career Center 20:37 Video 1, Root Replace & Ann Reconstr 21:56 Video 2, Bi-Atrial Cann for BVAD 24:17 Video 3, Pediatric Device Implant 26:23 Dr. Liao Interview 49:07 Upcoming Events 49:39 Closing They discuss the details of the procedure, including its background, ischemic time, technique, and postoperative outcomes. Additionally, they explore the application of the subxiphoid approach for robotic heart transplants and robotic mitral valve repair vs traditional open-chest (sternotomy) repair. Dr. Liao shares insights into the training and practice required for this operation and discusses the advantages of using robotics in heart transplants. He also reflects on what he would do differently in future procedures.   Joel also highlights recent JANS articles on the surgical implications of the 2023 ESC endocarditis guidelines endorsed by EACTS, the two-year results from the randomized CEASE-AF trial on the durable effectiveness and safety of hybrid ablation vs catheter ablation, a randomized trial on superficial parasternal intercostal plane block and full sternotomy, a comparison of the short- and long-term outcomes in patients undergoing sleeve lobectomy with or without buttressing the bronchial anastomosis, and intraspinal vascular perfusion territories of the descending thoracic aorta.  In addition, Joel explores free-style root replacement and annular reconstruction for destructive aortic root endocarditis, bi-atrial cannulation for biventricular assist device in children, and a device implantation in a 26 kg child. Before closing, Joel highlights upcoming events in CT surgery.    JANS Items Mentioned  1.) Surgical Implications of the 2023 ESC Endocarditis Guidelines Endorsed by EACTS: Bridging Guidelines and Practice   2.) Durable Effectiveness and Safety of Hybrid Ablation Versus Catheter Ablation: 2-year Results From the Randomized CEASE-AF Trial  3.) Superficial Parasternal Intercostal Plane Block and Full Sternotomy; A Randomized Trial  4.) Comparison of Short- and Long-Term Outcomes in Patients Undergoing Sleeve Lobectomy With or Without Buttressing the Bronchial Anastomosis  5.) Intraspinal Vascular Perfusion Territories of the Descending Thoracic Aorta  CTSNET Content Mentioned  1.) Free-Style Root Replacement and Annular Reconstruction for Destructive Aortic Root Endocarditis  2.) Bi-Atrial Cannulation for Biventricular Assist Device in Children  3.) Device Implantation in a 26 kg Child  Other Items Mentioned  1.) Guest Editor Series Webinar: Insights Into Pediatric Mechanical Circulatory Support  2.) Cardiac Surgical Arrest—An International Conversation Series    3.) Career Center   4.) CTSNet Events Calendar  Disclaimer The information and views presented on CTSNet.org represent the views of the authors and contributors of the material and not of CTSNet. Please review our full disclaimer page here.

Show NotesIn this episode of One in Ten, host Teresa Huizar speaks with Dr. Dylan Jones, a postdoctoral fellow at Penn State University, about the nuanced circumstances surrounding partial sibling placements in foster care. They explore the frequency, reasons, and impacts of cases where some siblings are placed in foster care while others remain at home. Key topics include the legal gaps in sibling visitation rights, the common scenarios leading to partial placements, and the implications for children's safety and well-being. Dr. Jones shares insights from his research utilizing Incans data and outlines future directions in understanding and improving outcomes for these children.  Time  Topic 00:00 Introduction to Sibling Separation in Foster Care 02:36 Exploring the Reasons for Sibling Separation 05:06 Frequency and Implications of Split Sibling Groups 05:48 Legal Gaps and Study Overview 08:52 Key Findings on Split Home Groups 12:23 Re-Reports and Long-Term Outcomes 19:40 Practical Implications for Caseworkers 21:26 Future Research Directions 27:22 Conclusion and Final Thoughts  ResourcesSometimes, Only Some Siblings Go to Foster Care: Exploring Split Sibling Groups in a Nationwide Sample - PubMedSupport the showDid you like this episode? Please leave us a review on Apple Podcasts.

Send us a textAssociation of a Count of Inpatient Morbidities with 2-Year Outcomes among Infants Born Extremely Preterm.Dorner RA, Li L, DeMauro SB, Schmidt B, Zangeneh SZ, Vaucher Y, Wyckoff MH, Hintz S, Carlo WA, Gustafson KE, Das A, Katheria A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.J Pediatr. 2025 Mar;278:114428. doi: 10.1016/j.jpeds.2024.114428. Epub 2024 Dec 4.PMID: 39643110Support the showAs always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

This week we review a recent important longitudinal follow up study of patients who have undergone palliation for the treatment of HLHS at The Children's Hospital of Philadelphia over the past 35+ years. What are the 'transplant-free' survival numbers at 35 years follow up following newborn palliation? Are there differences between hybrid and traditional "Norwood/Stage I" palliation? What factors explain the group of HLHS patients who do are 'super-Fontan's'? What accounts for the marked variability in outcomes of these complex patients? Dr. J. William Gaynor shares his deep insights both from his large scale paper and long-term experience caring for patients with HLHS.doi: 10.1016/j.jacc.2025.04.028

Will single session Y90 become the standard of care for HCC and oligo-metastatic disease? Tune in to our third installment of Dosimetry University with interventional oncologists Drs. Tyler Sandow, Nima Kokabi, and Kavi Krishnasamy as they share their experiences and best practices in single session Y90 treatment. --- This podcast is supported by:Sirtexhttps://www.sirtex.com/ Medtronic Emprinthttps://www.medtronic.com/emprint --- SYNPOSIS The doctors discuss the application and workflow of single session Y90 therapy for primary and oligo-metastatic liver tumors. They discuss the latest data from various institutions, emphasizing reduced lung dose, lower time to treatment, improved cost-efficiency, and the advantageous safety profile associated with single session treatment. The discussion also covers ideal patient selection based on tumor location and vascular characteristics, the importance of cone beam CT, and how to identify red-flag features of vascular enhancement. Our panel then reviews key technical considerations for single session success, including the use of flow-modifying microcatheters, gelfoam, and strategies for flow redirection. The episode concludes with a case discussion to explore the best strategy for a large liver tumor, detailing the specifics of each treatment and the potential role of combined therapies to achieve better long-term outcomes. --- TIMESTAMPS 00:00 - Introduction 00:47 - Single Session Y90: Workflow and Benefits03:52 - Patient Selection04:31 - Tumor Location and Preferred Techniques14:31 - Reperfusion and Redirection Techniques 26:16 - Case Study: Large Tumor Treatment37:01 - Long-Term Outcomes and Surgical Considerations

In this episode of the Award-winning PRS Journal Club Podcast, 2025 Resident Ambassadors to the PRS Editorial Board – Christopher Kalmar, Ilana Margulies, and Amanda Sergesketter- and special guest, Evan Matros, MD, discuss the following articles from the May 2025 issue: “Computer-Aided Design and Manufacturing in Free Fibula Reconstruction of the Mandible: Comparison of Long-Term Outcomes with the Conventional Technique” by Bengur, Humar, Saadoun, et al.  Read the article for FREE: https://bit.ly/CADCAMRecon Special guest, Evan Matros, MD is an attending surgeon, Vice Chair of Health Information Technology in the Department of Surgery, and the program director of the microsurgery fellowship at the Memorial Sloan Kettering Cancer Center in New York City. He completed his General Surgery and Plastic Surgery Residencies at Harvard Medical School followed by a microsurgery fellowship at Memorial Sloan Kettering Cancer Center. He also has received his MPH at Columbia University and Master of Medical Science degree from Harvard Medical School. Among his many accomplishments, Dr. Matros is the current vice president of the American Society for Reconstructive Microsurgery Council, he currently serves on the editorial board of the PRS Journal, and he is widely published in reconstructive microsurgery. READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCMay25Collection The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS

Send us a textJoin our host, Dr. Byron Stephens, as he speaks with Dr. Michael Kelly and Dr. Steven Glassman, two of the authors of Scoliosis Research Society–funded research recently published in the Journal of American Medical Association -- Surgery. Congratulations to all the authors on this outstanding achievement!The study, Long-Term Outcomes of Operative Versus Nonoperative Treatment for Adult Symptomatic Lumbar Scoliosis (ASLS): Durability of Treatment Effects and Impact of Related Serious Adverse Events Through 8-Year Follow-Up, was published in the Journal on April 2, 2025.To bring the study to its full 8-year follow up allowing for the JAMA publication, funding was provided by the SRS and several of the SRS industry partners and the International Spine Study Group . The SRS community and the study investigators appreciate the additional investments provided above and beyond their support of SRS, made by Globus Medical, K2M/Stryker Spine, Medtronic, NuVasive, and Zimmer Biomet.*The Scoliosis Research Society (SRS) podcast is aimed at delivering the most current and trusted information to clinicians that care for patients with scoliosis and other spinal conditions. From news in the world of spinal conditions, to discussions with thought leaders in the field, we aim to provide up-to-date, quality information that will impact the daily practice of spinal conditions.

In this episode, host Dr. Amber Luong speaks with Dr. Zara Patel. They discuss the recently published Original Article: “Long-term Outcomes of PRP Injections for Post-viral Olfactory Loss: A Prospective Cohort Study”. The full manuscript is available online in the International Forum of Allergy and Rhinology. Listen and subscribe for free to Scope It Out […]

In this episode of the Award-winning PRS Journal Club Podcast, 2025 Resident Ambassadors to the PRS Editorial Board – Christopher Kalmar, Ilana Margulies, and Amanda Sergesketter- and special guest, Evan Matros, MD, discuss the following articles from the May 2025 issue:   “The Financial Impact of a Cosurgeon in Breast Microsurgery” by DeVito, Ke, Park, et al.   “Legislative Impact and Persistent Disparities: Postmastectomy Breast Reconstruction Rates in the United States among 224,506 Patients” by Schafer, Ho, Potoczak, et al.   “Computer-Aided Design and Manufacturing in Free Fibula Reconstruction of the Mandible: Comparison of Long-Term Outcomes with the Conventional Technique” by Bengur, Humar, Saadoun, et al.   Special guest, Evan Matros, MD is an attending surgeon, Vice Chair of Health Information Technology in the Department of Surgery, and the program director of the microsurgery fellowship at the Memorial Sloan Kettering Cancer Center in New York City. He completed his General Surgery and Plastic Surgery Residencies at Harvard Medical School followed by a microsurgery fellowship at Memorial Sloan Kettering Cancer Center. He also has received his MPH at Columbia University and Master of Medical Science degree from Harvard Medical School. Among his many accomplishments, Dr. Matros is the current vice president of the American Society for Reconstructive Microsurgery Council, he currently serves on the editorial board of the PRS Journal, and he is widely published in reconstructive microsurgery.   READ the articles discussed in this podcast as well as free related content: https://bit.ly/JCMay25Collection   The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS.

Can the gender of your surgeon influence your outcome after surgery? New research says yes. In this episode of BackTable Urology, Dr. Christopher J.D. Wallis, a prominent urologic oncologist and health services researcher in Toronto, joins guest host Dr. Casey Seideman for a pivotal conversation at the intersection of surgical outcomes, gender, and health equity. This episode was developed in collaboration with the Society of Women in Urology (SWIU). --- SYNPOSIS Drawing from extensive studies and meta-analyses, Dr. Wallace highlights a significant mortality benefit for patients treated by female surgeons. The episode explores how these findings have sparked discussions on surgeon practices, patient care, and gender equity in medicine. Dr. Wallace also shares personal experiences to underline the importance of diversity and inclusive practices in healthcare. Finally, the two urologists discuss challenges faced when supporting diversity efforts and opportunities for future progress. --- TIMESTAMPS 00:00 - Introduction 04:01 - Personal Experience with Gender Bias in Surgery 07:05 - Groundbreaking Data on Surgeon Sex and Patient Outcomes 12:23 - Long-Term Outcomes and Consistency in Data 14:14 - Hypotheses and Underlying Reasons for Better Outcomes with Female Surgeons 20:18 - Impact on Healthcare Costs and Productivity 26:14 - Challenges and Pushback in the Medical Community 35:05 - Conclusion --- RESOURCES Society of Women in Urology https://swiu.org/home.aspx

Do we finally have definitive data on the efficacy of prostate artery embolization (PAE)? Dr. Shivank Bhatia (interventional radiologist at University of Miami) joins host Dr. Michael Barraza to discuss the findings from his prospective 1,075 patient study on the long-term outcomes of PAE, the largest longitudinal, single-center, single-operator, prospective study in the United States. --- This podcast is supported by: RADPAD® Radiation Protection https://www.radpad.com/ Medtronic MVP https://www.medtronic.com/mvp --- SYNPOSIS Dr. Bhatia begins by sharing his early years of training, and the steps he took to become an expert in all things PAE. He also covers how he helped build the PAE program at University of Miami, sharing several pearls for young IRs and trainees that are interested in bringing new service lines to their institutions. Dr. Bhatia then talks through the details of the study that he spearheaded, and encourages everyone to tune in - physicians and patients alike. --- TIMESTAMPS 00:00 - Introduction 05:12 - Building a PAE Program 18:55 - PAE Procedure Technicalities 22:30 - Post-Procedure Meds and Care 25:13 - Study Details and Patient Demographics 27:36 - Procedure Time and Technical Success 28:32 - Safety and Efficacy of PAE 38:06 - PSA Levels and Prostate Cancer 40:42 - Urinary Retention and Treatment Prioritization 45:17 - Re-Intervention Rates and Medication Independence --- RESOURCES Pisco et al (2011) - Prostatic arterial embolization to treat benign prostatic hyperplasia: https://pubmed.ncbi.nlm.nih.gov/21195898/ Bhatia et al (2024) - Prostatic Artery Embolization: Mid- to Long-Term Outcomes in 1,075 Patients: https://pubmed.ncbi.nlm.nih.gov/39532156/

This week we delve into the world of cardiovascular surgery when we review a recent multicenter ("Ross Collaborative") study of long term outcomes of the Ross procedure in newborns and infants. How durable of a repair is this in this young age range? How does the neo-aortic root grow with time? Why might the neo-aorta not dilate in this age group as much as is reported in older patients following the Ross procedure? Who is a candidate for this approach? How are decisions made between aortic valve repair and Ross procedure? Professor David Winlaw who is director of cardiovascular surgery at Lurie Children's Hospital/Northwestern University joins the podcast this week to discuss the results of this multicenter work on this topic of which he is the senior author.DOI: 10.1016/j.jtcvs.2024.06.030