Podcasts about systolic

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances, discusses a recently published original research paper on Systolic and Diastolic Blood Pressure, Cardiac Biomarkers, and Cardiovascular Mortality in Adults Without Cardiovascular Disease.

Lancet 1999;353:2001-07Background: Beta-blockers directly reduce cardiac contractility and myocardial oxygen demand. For decades, they were avoided in patients with acute and chronic heart failure over concerns they would facilitate decompensation of the condition. The therapeutic cornerstones of treatment, prior to the modern era of clinical trials, focused on managing symptoms and quality of life with diuretics and inotropic agents like digoxin; however, new paradigms were arising that focused on addressing neurohormonal mechanisms of chronic disease that were over-activated in the failing heart. The first major success came with inhibition of the renin angiotensin aldosterone system with angiotensin converting enzyme inhibitors whose effect on mortality for patients with mild and severe forms of chronic heart failure were demonstrated in the V-HEFT II, CONSENSUS, and SOLVD trials. Additional benefits were demonstrated with the mineralocorticoid receptor antagonist spironolactone in the RALES trial. These drug classes primarily work by reducing afterload and volume retention. Appreciating why they work for improving cardiac performance and managing symptoms in heart failure patients is straightforward when we consider the major factors that effect cardiac stroke volume - preload, afterload and contractility; however, it is also noteworthy the effects these agents have on sudden death. How beta-blockade benefits the failing heart is less obvious (outside prevention of sudden death). Mechanistic studies in patients with chronic heart failure have consistently shown that when beta blockers are used for more than 1 month, left ventricular function improves. Beta blocker therapy appears to restore the density of beta-adrenergic receptors after they have been downregulated by the chronic overactivity of the sympathetic nervous system. The first major placebo-controlled RCT to demonstrate a mortality benefit used the non-selective beta blocker carvedilol. The trial was small and not originally designed to test mortality and was stopped early without clearly predefined stopping rules. Furthermore, 8% of total patients selected for participation in the trial were excluded prior to randomization after a 2 week, open-label run-in phase with the study drug, which saw 2% of all patients experience worsening heart failure or death representing 24 patients (the difference in total deaths between groups was 9 when the trial was stopped). The Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) was the first large scale trial designed to test the hypothesis that beta-blockade with metoprolol controlled/extended release (CR/XL) added to optimum medical therapy reduces mortality in patients with chronic systolic heart failure.Patients: Patients were recruited from 313 sites in 13 European countries and the United States. Eligible patients were men and women between the age of 40 to 80 years with symptomatic heart failure (NYHA class II-IV) for >/= 3 months before randomization. They had to be on a diuretic and ACE inhibitor for at least 2 weeks. Other drugs, including digoxin, could also be used. Patients also had to have an EF of /=68 beats per minute.Patients were excluded if: they had an MI or unstable angina within 28 days; had an indication or contraindication for treatment with beta-blocker; beta blockade within 6 weeks; heart failure due to systemic disease (i.e., amyloidosis) or alcohol abuse; scheduled or performed cardiac transplant; an ICD; procedures such as CABG or PCI planned or performed in the past 4 months; 2nd or 3rd degree AV block unless a pacemaker was present; unstable or decompensated heart failure defined by pulmonary edema or hypoperfusion or supine systolic BP 25% deviation of the number of observed versus expected consumed placebo tablets during the run-in period.Baseline characteristics: The mean age of patients was 64 years and approximately 78% were male. Slightly more than 30% of patients were above the age of 70. The average EF was 28%. The average SBP was 130 mmHg and heart rate was 82 bpm. Most patients had mild to moderate heart failure, with 41% in NYHA Class II, 56% in Class III, and only 3% in Class IV. Ischemic cardiomyopathy accounted for 65% of cases and nonischemic causes accounted for 35%. Most patients were on an ACE inhibitor or ARB (95%) and diuretic (90%). Digoxin was used in 63%. Trial procedures: Prior to randomization, the study was preceded by a single-blind, 2-week placebo run-in period. Patients meeting eligibility were then randomized to placebo or metoprolol CR/XL. The starting dose of placebo or metoprolol CR/XL was 12.5 mg daily for patients in NYHA class III or IV and 25 mg daily for patients in NYHA class II. The dose was doubled every 2 weeks until the target dose of 200 mg daily was reached. Patients were followed every 3 months.Endpoints: The primary outcome was all-cause mortality. It was estimated that 3,200 patients would need to be followed for 2.4 years to detect a 30% relative reduction in mortality based on annual mortality rate of 9.4% in the placebo group. This would achieve at least 80% power with a 2-sided alpha of 0.04. Patients were recruited faster then planned and so the final sample size of 3,991 patients increased the power of the study.The study was monitored by an independent safety committee and predefined stopping rules for efficacy were based on all-cause mortality, done when 25%, 50%, and 75% of expected deaths had occurred. Results: The trial was stopped early after the 2nd preplanned interim analysis when 50% of expected deaths had occurred. The mean duration of follow-up at the time of stopping was 1 year. The mean daily dose of metoprolol CR/XL was 159 mg once daily, with 87% receiving 100 mg or more and 64% receiving the target dose of 200 mg daily. In the placebo group, the corresponding values were 179 mg daily, 91% and 82%. The study drug was discontinued permanently in 14% of patients in the metoprolol group and 15% in the placebo group. Six months after randomization, heart rate decreased by 14 bpm in the metoprolol group compared to only 3 bpm in the placebo group. Systolic blood pressure decreased less in the metoprolol group (-2.1 vs 3.5 mmHg).Compared to placebo, metoprolol significantly reduced all-cause mortality (7.3% vs 10.8%; RR 0.66; 95% CI 0.53—0.81). Cardiovascular mortality accounted for 91% of all deaths; with sudden death accounting for 58% and death from worsening heart failure accounting for 24% of all deaths. All 3 of these causes of death were significantly reduced by metoprolol. The relative and absolute effects on death were greatest for patients with NYHA class III heart failure.Conclusions: In this trial of stable patients with mild to moderate chronic systolic heart failure, who were optimized on an ACEi or ARB and diuretic, metoprolol CR/XL significantly reduced all-cause mortality. Approximately 30 patients would need to be treated with metoprolol compared to placebo for 1 year to prevent 1 death. This trial represents a significant win for beta blockade in patients with chronic systolic heart failure. While the NNT in this trial is slightly higher than in SOLVD, it is important to appreciate that follow-up time in SOLVD was more than 3x longer. Limitations to external validity in this trial include the run-in period and stringent inclusion and exclusion criteria. Our enthusiasm is also tempered by early stopping, which has been found to be associated with false positive or exaggerated results but this concern is mitigated to some extent in this trial because the rules for early stopping were clearly defined in the protocol.Cardiology Trial's Substack is a reader-supported publication. To receive new posts and support our work, consider becoming a free or paid subscriber. Get full access to Cardiology Trial's Substack at cardiologytrials.substack.com/subscribe

A recent 12-week randomised controlled trial involving healthy adults aged 55-70 yielded significant positive findings regarding pomegranate extract's effect on blood pressure. While the study might not have shown significant differences compared to placebo across all initially measured markers, it revealed important reductions within the group taking pomegranate extract daily. Specifically, participants supplementing with pomegranate extract saw a statistically significant average decrease in Systolic Blood Pressure (SBP) by 5.22 mmHg and Diastolic Blood Pressure (DBP) by 3.6 mmHg. The researchers highlight the potential clinical relevance of the SBP reduction, noting that a 5 mmHg drop is associated with an estimated 10% decrease in the risk of major cardiovascular events. These findings align with previous research and meta-analyses confirming pomegranate's blood pressure-lowering effects, suggesting pomegranate extract could be a supportive strategy for hypertension prevention in older adults."This information is for educational purposes only and should not be interpreted as medical advice.""The study discussed was a randomised controlled trial in healthy adults aged 55-70.""The significant positive findings highlighted are the reductions in Systolic and Diastolic blood pressure observed within the group taking pomegranate extract. The authors note the SBP reduction is potentially clinically relevant.""These blood pressure findings are consistent with other studies and meta-analyses on pomegranate, strengthening the evidence for this specific effect.""Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially regarding blood pressure management or if you have existing health conditions or take medications.""This channel is not monetized and does not provide medical advice."#PomegranateExtract, #BloodPressure, #SystolicBloodPressure, #ClinicalRelevance, #HypertensionPreventionFarhat G, Malla J, Vadher J, Al-Dujaili EAS. Effects of Pomegranate Extract on Inflammatory Markers and Cardiometabolic Risk Factors in Adults Aged 55–70 Years: A Randomised Controlled Parallel Trial. Nutrients. 2025; 17(7):1235.

Commentary by Dr. Katie Ruddy.

In this video on research published in JACC and presented at ACC.25, Yuan Lu, ScD, JACC: Executive Associate Editor, discusses her study on optimal blood pressure management for adults aged 80 and above. Her study found that systolic blood pressure below 130 mmHg is associated with lower cardiovascular risk, while levels above 145 mmHg increase heart-related mortality. The study supports intensive blood pressure management but emphasizes the need for personalized treatment and further research on long-term effects and potential risks.#jacc #jaccjournals #acc25

Understanding systolic vs. diastolic heart failure is crucial for anesthesia providers, as both conditions present unique challenges in the operating room. In this episode, Terry and Gary break down the key differences between these two types of heart failure, their underlying mechanisms, and the best strategies for anesthesia management. They discuss the risk factors, symptoms, and pathophysiology of each condition, as well as how preoperative evaluation can help identify high-risk patients. The episode also covers the importance of intraoperative monitoring, fluid management strategies, and why tailoring anesthesia care to each patient can significantly improve outcomes. Tune in as they unpack the latest evidence, share real-world experiences, and provide practical takeaways for managing heart failure patients in the OR. Here's some of what we discuss in this episode:

In this episode, Dr. Valentin Fuster summarizes the March 11, 2025 issue of the JACC, which features groundbreaking research on transcatheter aortic valve replacement (TAVR) and its expanding applications. The podcast delves into the latest studies on TAVR's impact on heart failure patients, the need for better patient selection, and how new findings are shaping the future of aortic stenosis treatment.

Commentary by Dr. Jian'an Wang.

William H. Sauer, MD, FHRS, CCDS, Brigham and Women's Hospital is joined by Edoardo Bressi, MD Queen Elizabeth Hospital - University Hospitals Birmingham, and Jordana Kron, MD Virginia Commonwealth University to discuss the current guidelines that present varying classes of recommendations for implantable cardioverter-defibrillator (ICD) utilization in patients with cardiac sarcoidosis (CS) and left ventricular ejection fraction (LVEF)

TAVR UNLOAD: Transcatheter Aortic Valve Replacement in Patients with Systolic Heart Failure and Moderate Aortic Stenosis

Darshan H. Brahmbhatt, Podcast Editor of JACC: Advances discusses a recently published original research paper on an association between systolic blood pressure time in target range indices and adverse cardiovascular outcomes.

Commentary by Dr. Jian'an Wang.

Artista Nacida en Colombia, Pereira. Estfana; es la encarnación de una artista abstracta, decidida y definida. Permanece en su búsqueda de crear experiencias sensoriales y sonoras que trascienden lo ordinario. Dentro de los ámbitos del Ambient, Deep, Dub y Techno, el viaje creativo de Estfana se desarrolla tejiendo un tapiz de paisajes sonoros futuristas. Su enfoque único invita a los oyentes a profundizar en los reinos intangibles de la conciencia, donde los límites entre la percepción y la realidad se desdibujan. A través de su música explora la convergencia de lo efímero, invitando al público a embarcarse en un viaje sonoro transformador. Con cada composición, desafía las nociones convencionales del sonido, llevando los límites de la creatividad sonora a otro nivel. Actualmente esta vinculada a la agencia Europea de bookings "Systolic". Es la directora y diseñadora de la revista digital y canal de podcast internacional de música electrónica AXTTRAL COLOMBIA/AXTTRAL SERIES, y continua en constante preparación como productora musical. ARTISTS Links: ESTFANA: SC: @estfanacol FB: https://www.facebook.com/estfanacol IG: https://www.instagram.com/estfanacol/ MEDELLINSTYLE: SC: @medellinstyledj FB: www.facebook.com/culturaelectronica IG: www.instagram.com/medellinstyle/?hl=es-la

JACC Associate Editor Theresa McDonagh, MBBCH  speaks with author Akshay S. Desai, MD, FACC about this paper on pulse pressure published in JACC and presented at AHA. In a pooled analysis of 16,950 patients with chronic HFmrEF or HFpEF enrolled from 4 global randomized clinical trials, a J-shaped relationship was observed between SBP and the risk of adverse CV events, with the lowest risk occurring at SBP values between 120 and 130 mmHg. A similar pattern was seen with PP, with the lowest risk found between 50 and 60 mmHg. Both higher SBP and higher PP independently predicted adverse CV events. Notably, PP remained a strong predictor of CV risk, independent of baseline SBP.

Author Nicolas M. Van Mieghem, MD, PhD, FACC, and JACC: Executive Associate Editor Aakriti Gupta, MD, FACC,  discuss the TAVR UNLOAD trial, which focused on patients with moderate aortic stenosis (AS) and reduced ejection fraction (HFrEF). The trial found no significant difference in the primary endpoint (composite of mortality, stroke, and hospitalizations) between the TAVR and clinical surveillance groups. However, patients who underwent TAVR showed a significant improvement in quality of life at one year. The conversation highlighted the need for individualized treatment approaches, emphasizing patient selection, while also considering trial limitations, including slow enrollment and study size.

In this episode, I take a brief look at blood pressure and why it's important to monitor our body's own canals of life. I studied the circulatory system back in 2008, prior to completing my coursework and exams for my qualifications in sports massage therapy and personal training, of which I recall was a far more complex subject matter than I had anticipated. Blood pressure is essentially the amount of pressure circulating against the walls of blood vessels, the majority coming from the heart pumping blood through our circulatory system. We have the following two terms when measuring this. Systolic (max pressure per heart beat) and Diastolic (min pressure between two heart beats). These measurements are taken in millimeters of mercury above the surrounding atmospheric pressure, this is known as (mmHg). Health care professionals often take our blood pressure readings, alongside various other vital signs, with a normal resting BP of 120 (mmHg) Systolic and 80 (mmHg) Diastolic being ideal for adults. Excessively low BP is known as hypotension and consistently too high is known as hypertension, normal is known as normotension. Chronic hypertension (high blood pressure) can cause a multitude of complications from stroke and heart disease to kidney failure, therefore it's advisable to visit your GP surgery for BP testing, or take your own readings at home with a quality automated kit. Lifestyles are an important factor to consider when addressing our BP, from workplace surroundings and driving to household habits and nutrition. We all know that physical inactivity plays a major role in unhealthy BP and as such cardiovascular exercise (walking, running, swimming, cycling, rowing) or even moderate to high intensity resistance based training are essential in the lifelong maintenance of our circulatory system. Stress induced lifestyles are commonplace in hypertension, often brought on by external factors, such as highly populated towns and cities, elevated crime rates, increased road traffic, target driven sales professions, cluttered households, raising children, marriage, divorce, financial problems and mentally/ emotionally subscribing to political ideologies, through mass hysteria social media outlets. As a professional personal trainer I often take clients blood pressure readings, alongside body composition and grip strength, with an eye on reducing hypertension through exercise, sleep and nutritional improvements. Alcohol and salt consumption are discussed during appointments, which clients can immediately make inroads to reducing one or both, by way of complete abstinence form alcohol and removing added salt in cooking / avoiding salt laden processed foods until hypertension readings are lowered. This is possibly more beneficial than a weekly exercise appointment, as salt and alcohol are generally available morning to night, seven days a week, whereas structured exercise appointments are usually one hour per week, or two if a client has excessive weight / body fat loss targets. Look after your heart and blood vessels folks and remember to ask for professional advice if you have concerns regarding low or high blood pressure. Listen to the episode here or on Spotify, Apple Podcasts and Amazon Music or watch the video on YouTube. Please subscribe to the channel for more free content and feel free to comment and share with your friends, family and colleagues. Thanks for listening.

Host Praveen Ranganath is joined by friend and former podcast guest, Vinit Baliyan, to discuss the advantages and disadvantages of systolic imaging in cardiac CT. 

February is American Heart Month. When's the last time you measured your blood pressure? Do you know what "good" blood pressure even is? Or what about "good" cholesterol?Brush up on the fundamentals – and get some clear guidelines for keeping tabs on your heart health - from Dr. Marc Eisenberg, a cardiologist from NewYork-Presbyterian and Columbia.Click here for the episode transcript. 

Droneghost is the main musical project of Jaume Muntsant, producer and dj from Barcelona. The project started in 2015 with the intention of creating a dark sound universe, inspired by David Lynch, Lovecraft, Spanish ghost stories and other mysteries through the combination of techno, ambient and drone elements. Since then he has released his music on several labels such as Space Textures, Circular Limited, Aarden Records or Systolic, as well as on his own Bandcamp. This live set was recorded live at the Midline night organized by ABSIS at LAUT in Barcelona last year. The live set is made up of the sounds, loops and remixed patterns of Droneghost's material, working with Ableton as the main element and accompanied by a drum machine. Follow: Bandcamp: https://droneghost.bandcamp.com/ Soundcloud: https://soundcloud.com/droneghost Facebook: https://www.facebook.com/droneghost Instagram : https://www.instagram.com/_nigul_/ Discogs: https://www.discogs.com/es/artist/4011420-Droneghost

Welcome to a new episode where we're focusing on a vital aspect of health: Blood Pressure management. Join us as we explore key concepts and practical strategies to maintain healthy blood pressure levels.What's Inside:Understanding Blood Pressure:Systolic vs. Diastolic: We start by breaking down what these terms mean. Systolic pressure is the force your heart exerts on the artery walls during a heartbeat, while diastolic pressure is the pressure between beats.The Significance: Learn why maintaining a balance between these two readings is crucial for your overall health.Recognizing the Symptoms:High Blood Pressure (Hypertension): We discuss common signs like headaches, shortness of breath, and nosebleeds, and why they shouldn't be ignored.Low Blood Pressure (Hypotension): Learn about symptoms such as dizziness and fainting, and when to seek medical advice.Real-Life Success Story:A Client's Journey: Hear about how one of our clients, whom we'll call "John," successfully reduced his high blood pressure.The Three-Pronged Approach:Diet Modification: Understand how John changed his eating habits, focusing on heart-healthy foods and reducing sodium intake.Regular Exercise: Learn about the exercise regimen John adopted that significantly contributed to lowering his blood pressure.Stress Management: Discover the relaxation techniques and lifestyle changes John implemented to manage stress effectively.Takeaways:Simple Steps, Big Impact: Realize how small changes in your daily routine can lead to significant improvements in blood pressure levels.Empowerment Through Knowledge: Gain the information you need to take control of your blood pressure and improve your overall health.Resources:Best Home Blood Pressure Monitors.Closing Thoughts:Join us in making informed health choices. Whether you're looking to understand your blood pressure readings better or seeking effective strategies to manage them, this episode has something for you.Remember, you're not alone in this journey. We're here to guide and support you every step of the way. Tune in, learn, and start transforming your health today!Connect with Us:Have questions or thoughts about this episode? Reach out through our social media channels or email us. We love hearing from you!Useful LinksYoutube ChannelElevate Health Chiropractic and Wellbeing WebsiteElevate Health Online Membership Registration

1.06 Systolic Heart Murmurs Cardiovascular system review for the USMLE STEP 1 Exam Heart murmurs are caused by turbulent blood flow in the heart There are 4 different types of systolic murmurs: ventricular septal defect (VSD), patent ductus arteriosus (PDA), aortic stenosis, and mitral or tricuspid regurgitation PDA produces a constant, machine-like murmur VSD produces a harsh holosystolic murmur Aortic stenosis produces a crescendo-decrescendo systolic ejection murmur Mitral and tricuspid regurgitation produce a holosystolic high pitched "blowing" murmur Mitral valve prolapse produces a mid-systolic click followed by a late systolic murmur Aortic regurgitation produces a decrescendo diastolic murmur Mitral stenosis produces a rumbling diastolic murmur  

Dr. Martin answers questions sent in by our listeners. Some of today's topics include: Artichoke extract Blood disorders C. difficile bacteria Cayenne pepper Vitamin D with K2 Diabetics & intermittent fasting Systolic blood pressure Coming off statin drugs When to take probiotics Cold water immersion  

CHEST June 2023, Volume 163, Issue 6 Siddharth Dugar, MD, FCCM, FASE, and Abhijit Duggal, MD, MPH, MSc join CHEST Podcast Moderator, Dominique Pepper MD, to discuss whether left ventricular systolic dysfunction is associated with increased mortality among patients with sepsis and septic shock. DOI:https://doi.org/10.1016/j.chest.2023.01.010   Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.

Click here to access The OUTSMART Classroom, so you and your community can Outsmart OBESITY, HEART DISEASE & METABOLIC SYNDROME.Click here to get the OUTSMART CLASSROOMClick here to get the OUTSMART BOOKClick here to get the OUTSMART HEALTH LABClick here if you are a teacherClick here if you are a Cardiology practice or allied health professionalClick here to learn about Shane.Today's episode...The Biggest Public Health Problem of the 21st Century and The Biggest Public Health Crisis of the 21st Century are not the same thing. After my 37 years teaching health and physical education, plus my work with over 100 PhD's in disciplines like cardiology, exercise physiology, vascular medicine, molecular biology, public health, exercise oncology, and many more...I am convinced that we must solve one of these before the other, if you and your community ever stands a chance to become classified as medically healthy.Find out in today's episode how two metabolic conditions inside your body will impact your risk of dying early. See the new video of the Outsmart Classroom at this website:  OUTSMART Classroom

Sisko Electrofanatik @ Systolic Tracklist: Michael Klain - Der Sturm kommt (Original Mix) Kos:mo - Reload Ride Gaga, Mateo! - Wolf Patrick Branch - Black Marsh (Original Mix) Planetary Assault Systems - In From The Night(Adam Beyer & Wehbba Remix) Sisko Electrofanatik - Solar Rock Nicolas Taboada - Circles Daniel Boon - Kodiak Sisko Electrofanatik, Dino Maggiorana - Desolate Lilly Palmer - Resonate Sisko Electrofanatik - Ametista (Original Mix) Sisko Electrofanatik - My Realm (Original Mix) Quadrophonia - Quadrophonia (Dark Dub) A.D.H.S. - Razor Sisko Electrofanatik - Apnea (Original Mix) The Advent - Format (Marco Faraone Remix) Sisko Electrofanatik - Ametista (Tiger Stripes Remix) Thomas Schumacher - You Belong Here (Sisko Electrofanatik “Belonger” Remix) Peter Fern & Siasia - Hyperion T78 - Truckter (2K23) (Extended Mix) Lander B - Dobby Linear Phase - Disappointment One Sisko Electrofanatik - Ziggurat Nakadia, Ramiro Lopez - Blunda (Gary Beck Dub Mix) Marbox - Tunnel Vision Sisko Electrofanatik - Once Again Adam Beyer, Bart Skils - Your Mind (Charles D Epic Mix)

Trade – ApresolineClass – Vasodilator MOA – Directly dilates peripheral blood vesselsIndication – HTN associated with preeclampsia and eclampsia, HTN crisis Contraindication – Patients taking diazoxide or MAOI's, coronary artery disease, stroke, angina, dissecting aortic aneurism, mitral valve and rheumatic heart disease. Side effects – Headache, angina, flushing, palpitations, reflex tachycardia, anorexia, N/V, diarrhea, hypotension, syncope, peripheral vasodilation, peripheral edema, fluid retention, pareshesias. DosingPreeclampsia and eclampsia:         Adult : 5-10mg IV repeat every 20-30mins until Systolic pressure of 90-105mmhgAcute HTN ( not associated with preeclampsia )        Adult :10-20mg IV/IM        Pedi : 1mo – 12yr  0.1-0.2 mg/kg IV/IM max 20mg per dose

1.06 Systolic Heart Murmurs Cardiovacular system reveiw for the USMLE Step 1 exam. Heart murmurs occur when blood flow is turbulent in the heart, producing a whooshing or swishing sound 4 different sounding systolic murmurs discussed: Ventricular septal defect, patent ductus arteriosus, aortic stenosis, and mitral/tricuspid regurgitation Patent ductus arteriosus is a machine-like murmur that is constant (heard during systole and diastole) Patent ductus arteriosus: "People who constantly PDA deserve to be thrown in a machine" Ventricular septal defect produces a harsh holosystolic murmur (only heard during systole) Ventricular septal defect: "Holy cow, its harsh being born with a VSD" Aortic stenosis produces a crescendo-decrescendo systolic ejection murmur (heard during systole) Aortic stenosis: "ASS CD (insert your least favorite band here, I'll say Nickelback)"   Mitral and tricuspid regurgitation produces a holosystolic high pitched "blowing" murmur (heard during systole) Mitral and tricuspid regurgitation: "It sucks to climb Mt regurgitation. Climbing Mt regurgitation blows." The location and cause of the murmur can indicate whether it is mitral or tricuspid regurgitation

Commentary by Dr. Valentin Fuster

Today on War on Weight, I have Michelle McCoy from the Treasured Wellness podcast. Michelle is a certified Holistic Health coach and specific passions are: Adrenal Fatigue, Auto-Immune Disorders and Spiritual Health.   I'm super excited to have this conversation with her and talk about the foundations of a healthy life and the goal of optimal health for women over 40. When I listened to her podcast, I was like YES, YES, YES!   She spoke my language and reiterated so many of the basic health principles that are the foundations of the program that helped me lose 56 pounds*, OPTAVIA.  There are many ways to get to optimal health and I love having conversations and learning different ways to get there.    Michelle shares some key ways women over 40 can get to optimal health by putting just a few  healthy habits into place.    I love the wisdom she brings to the show today and how it connects the habits of health I put into practice in my life to finally win the war on my weight.   In the book Habits of Health, Dr. A states “a key study was published in the Arch of Internal Medicine. They evaluated over 25,000 people and concluded that by adhering to four simple lifestyle factors, you can reduce your risk of developing major chronic disease by 80%! Those lifestyle factors are: • No smoking • Have a BMI less than 30 • Perform three and a half hours a week or more of physical activity • Adhere to dietary principles such as a high intake of fruit, vegetables, whole grain bread, and lower your meat consumption Optimal and Ultrahealth™ Guidelines. Here are the key parameters we're aiming for: Systolic blood pressure 110–95 or less Diastolic blood pressure 75–60 or less Body mass index 24.9–19.5 (around 20 is ideal; no less than 18.5) Body fat 10% for men; 17–23% for women HDL (good cholesterol) 50–70 mg/dl Fasting blood sugar 75 mg/dl If I've said it once, I've said it a hundred times, this book is GOLD!  It's why I give a free copy to my clients with their first order because I don't want my clients to miss the magic of the program.  These books take you from diet mentality to lifestyle change. I have a passion to serve women and help them get to optimal health, so I'm here with resources to help you get to your optimal health whether it's a program I coach or another amazing coach that I have met along my journey. Michelle offers a beautiful holistic perspective on health and wellness for women, and I know you are going to love her as much as I do.   If you are interested in finding out more about her podcast, her services and to grab that FREE Foggy & Fatigued Blueprint, head on over to treasuredwellness.com.   Here's the direct link to EPISODE 80 :  Treasured Wellness Episode 80     EXCITING NEWS:  I've Co-authored an amazing new book called UNLEASH HER.  It releases on October 25th, you can order your personally signed copy from me by visiting coachkeatha.com and clicking UNLEASH HER.     You can also contact me, subscribe to my email list to get a weekly newsletter with great new tips and recipes and check out my new program coming: The Revelation Wellness; all on coachkeatha.com      *In a clinical study, the group on the Optimal Weight 5 & 1 Plan® lost 10x more weight than the self-directed group. Average weight loss on the Optimal Weight 5 & 1 Plan is 12 pounds (5.4 kg).  

On this episode I sat down with the amazing Dr Cliff Reid to discuss his approach to hypotension. Cliff is a senior Staff Specialist/retrevialist with a special interest in Resuscitation. On the episode we discussed diagnosis, treatment , vasopressors and fluid status. Cliff will leave you with an overload of extremely useful information that you can implement in your own environments.            Show Notes    Hypotension is usually bad: The significance of non-sustained hypotension in emergency department patients with sepsis    Causes of hypotension - and PEA cardiac arrest: the 3 plus 3 rule Lactate doesn't always mean sepsis!   Systolic blood pressure below 110mmHg is associated with increased mortality in blunt major trauma patients

Commentary by Dr. Valentin Fuster

Commentary by Dr. Valentin Fuster

Commentary by Dr. Valentin Fuster

Trade: DobutrexClass: Adrenergic agent, InotropicMOA: Increases myocardial contractility and stroke volume with minor chronotropic effects, resulting in increased cardiac outputIndication: CHF, Cardiogenic shockContraindications: Drug induced shock, Systolic pressure greater then 100, use caution in HTN, recent MI, Arrhythmias, hypovolemia Side effects: Tachycardia, PVC's, HTN, Hypotension, palpitations, arrhythmiasDosing:Adult: 2-20 mcg/kg/min IV/IOPedi: SAA

Do you have trouble hearing and interpreting heart sounds? Systolic vs. diastolic murmurs, S3 vs. S4 gallops? In this episode, we'll review strategies on how to listen to common heart sounds so you're no longer intimidated by this topic on board questions or rounds. This episode pairs well with our Season 2 episode on Valvular Heart Diseases, which delves deeper into the physiology of common heart murmurs. Welcome to Season 3 of the podcast!

In this episode, Sophia Khattak discusses key points from a recent case report published in EHJ – Case Reports.

When was the last time you had your blood pressure checked? Do you know what your resting heart rate is? If you're exercising to lose weight or change the way you look, there are some important health markers you can use to track your progress instead. On this episode, Dr Sarah explains why you should keep an eye on your blood pressure and your heart rate. The information in this podcast is for general use, always consult your doctor or physiotherapist before undertaking a new exercise program. Contact us:womenlikeyoupodcast@gmail.com   WLY resources and recommendations: Australian guidelines to reduce health risks from drinking alcohol https://www.nhmrc.gov.au/health-advice/alcohol  CVD checkhttp://www.cvdcheck.org.au/calculator Influence of Physical Activity on Hypertension and Cardiac Structure and Function https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624627/#R6 Physical Activity and the Prevention of Hypertensionhttps://pubmed.ncbi.nlm.nih.gov/24052212/ Target Heart Rate and Estimated Maximum Heart Ratehttps://www.cdc.gov/physicalactivity/basics/measuring/heartrate.htm WLY newsletter subscription  The Women Like You podcast is recorded on the lands of the Gadigal people of the Eora nation. We pay our respects to elders past, present and emerging. We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the land where we live, work, and exercise. See omnystudio.com/listener for privacy information.

April 2020 Speckle Tracking Analysis of Left Ventricular Systolic Function Following Traumatic Brain Injury: A Pilot Prospective Observational Cohort Study Narrator: Jacqueline Morano, MD

Commentary by Dr. Julia Grapsa

Latest pieces of evidence regarding the use of RAAS inhibitors in heart failure patients

Latest guideline recommendations on the use of RAAS inhibitors in heart failure patients

Andy, Dan and Tyler sit down for a sesh. We cut out all the talk about porn and taking shits to bring you this short episode. All our guests have tv credits. try not 2 cum.

Neprilysin Inhibitors to prevent LV remodeling post MI

Commentary by Dr. Valentin Fuster

On this episode Dave is joined by Dr. Jerry W. Jones, MD FACEP FAAEM, to discuss why ST elevation is not always an infarction. Dr. Jones will highlight why we need to think about morphology and shape when interpreting ECGs and why reciprocal changes are just as important as the primary changes and more!    Dr. Jones is the CEO and Founder of Medicus of Houston. Medicus of Houston is a continuing medical education company that specializes in advanced ECG interpretation and instruction.  He is a Board-certified emergency physician, author, speaker, instructor and and internationally-recognized expert in electrocardiography. Dr. Jones is a diplomate of the American Board of Emergency Medicine who has practiced internal medicine and emergency medicine for over 40 years. Also In This Episode How to diagnose real infarctions How ischemia damages the cell Cells creating electrical current How electrical current creates is responsible for ST depression and elevation Systolic and Diastolic currents of injury How not to confuse subendocardial ischemia with reciprocal change    Subscribe to the video version of this podcast to have access to the visuals that accompany the audio as well as additional tools and resources to help improve your understanding.  Subscribe now at CurrentECG.com  And Stay Current!  

Episode 72- Systolic by Keith Poniewaz and Dan Fallon (hosts)

CAMP MINGO! KEITH'S BLOOD PRESSURE! TIES!

Narrator: Jacqueline Morano, MD