Digital Therapeutics Podcast with Eugene Borukhovich

Welcome to the DTx Podcast, where we explore the latest in digital therapeutics. In our previous episode with Mike Pace, we discussed the challenges facing DTx in 2023. Now, with positive developments in 2024, we're updating our community on the progress in advancing digital therapies. Host Eugene Borukhovich engages with experts Dr. Jenna Carl, Andy Molnar, Marty Culjat, and Kirsten Tullia to discuss the latest trends, challenges, and opportunities in the DTx industry. [00:30] Expanding US channels and mental health access [05:15] Software-wearable integration and commercial models [12:45] Coverage expansion impact on Medicare and Medicaid [18:10] Evolution of DTx and reimbursement challenges [23:30] Investor impatience and R&D impact [28:00] Medicare reimbursement and investor interest in DTx Tune in to the DTx Podcast to gain valuable insights into the evolving world of digital therapeutics and stay updated on the latest trends, legislative impacts, and entrepreneurial advice from industry leaders. If you'd like to learn more about sponsorship opportunities across Mission Based Media assets, visit our website at https://missionbasedmedia.com/ Guest Links and Resources: Connect with Dr. Jenna Carl on Linkedin Connect with Andy Molnar on Linkedin Connect with Marty Culjat on Linkedin Connect with Kirsten Tullia on Linkedin Listen to the episode with Mike Pace Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode of the DTx Podcast, Eugene Borukhovich sits down with Mike Pace, CEO and founder of PalmHealthCo, to delve into the latest developments and insights from the DTx industry from 2023 and to discuss what may be in store for 2024. Eugene and Mike cover various aspects of the DTx landscape, including the growing importance of FDA authorizations, the shift towards non-prescription solutions, and the maturation of the industry into operations and pricing. Learn more about the impact of FDA authorizations on scalability in the US healthcare system, the strategic integration of digital therapeutics with virtual care models, market consolidation, and the effects of decreased venture funding on the industry. 1. [04:00] What has the industry learned from Pear Therapeutics' initial growth and scaling and, ultimately, its bankruptcy? 2. [10:45] Mike mentions the importance of FDA authorizations for scalability in the US healthcare system. How does he foresee potential FDA approvals shaping the landscape for digital therapeutics in the near future? 3. [15:20] PalmHealthCo has been involved in integrating DTX with virtual care and pushing for a virtual first go-to-market model. How has this approach impacted their journey and success in the DTx space, and what are the potential implications for the industry as a whole? 4. [20:10] What is the importance of high-quality clinical evidence for achieving permanent listing under regulatory laws? How critical is this evidence generation for the future of digital therapeutics, and what challenges does Mike anticipate in this regard? 5. [25:40] Considering the rise of aggregators in the healthcare industry influencing the market for digital therapeutics, what strategies can DTx companies employ to navigate this evolving landscape? 6. [30:15] With the current state of venture funding and market consolidation in digital health, what advice does Mike have for startups in terms of maintaining a focus on positively impacting patients and families while navigating the industry's challenges? Tune in to the DTx Podcast to gain valuable insights into the evolving world of digital therapeutics and stay updated on the latest trends, legislative impacts, and entrepreneurial advice from industry leaders. Guest Links and Resources: Connect with Mike Pace on LinkedIn Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode of the DTx Podcast, Eugene Borukhovich hosts Philip Heimann, CEO of Vivira, a prominent player in the DTx landscape in Germany. "The genesis of Vivira was the need for personalized movement therapy - we wanted to provide people with a solution that was made just for them," says Philip.  This necessity led to the development of an innovative digital therapeutic solution that has made a significant impact in the market. Eugene and Philip dive into the profound impact of the DiGA law in Germany, passed in 2019, on Vivira's market growth. This legislation enabled general reimbursement and physician involvement in prescribing the app, marking a pivotal turning point for the company and the broader DTx landscape in Germany. In addition, Philip sheds light on the challenges faced by DTx startups in understanding the market complexities and securing suitable funders. He stresses the importance of selecting investors who can offer long-term support and emphasizes the significance of focusing on long-term goals and building high-value companies. 1. [05:30] What challenges did Vivira face in the early stages, being almost exclusively angel-funded, and how did this contribute to the development of their DTx solution? 2. [10:45] What pivotal role has the DiGA law played in enabling Viveira's growth in the market, and what are the implications of this legislation for other DTx companies in Germany? 3. [15:20] How has Vivira's approach of not starting in the direct-to-consumer market and focusing on the DIGA prescription model influenced its journey and success in the DTx space? 4. [20:10] What is the significance of high-quality clinical evidence, particularly RCT studies, for achieving permanent listing under the DiGA law? 5. [25:40] What are the challenges and potential solutions regarding the activation of digital therapies prescribed by doctors? 6. [30:15] As a serial entrepreneur, what critical advice does Philip have for DTX startups in navigating the complexities of the market and choosing investors? Join us on the DTx Podcast for valuable insights into the world of digital therapeutics, covering topics from legislative impacts to entrepreneurial advice. Subscribe now to stay updated on the latest episodes and continue exploring the dynamic realm of DTx. Guest Links and Resources: Connect with Phillip Heimann on LinkedIn Visit Vivira Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Josh Sackman, President and Co-founder of AppliedVR. AppliedVR, in their own words, provide virtual reality-based treatments that represent a comprehensive approach to chronic pain that empowers patients with accessible digital tools self-managed in their own home. In this episode, we cover: The origin story of AppliedVR Transitioning from an app store for health VR to focus pain management market Patient experience and the pain management pipeline Funding journey and key funding milestones The scientific hypothesis of "mind over matter" behind AppliedVR's approach and evidence generation journey The FDA approval process for AppliedVR and lessons learned for entrepreneurs. AppliedVR's current business hypothesis and scaling plan Market channels and scaling VR Guest Links and Resources: Connect with Josh Sackman on LinkedIn Visit www.appliedvr.io Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this replay episode, we hear from Sylvain Piquet, COO and Co-founder of Five Lives, the app that leverages the new science of brain aging, neuroplasticity, and cognitive reserve to help people improve their brain health and prevent cognitive decline and dementia. In this episode, we cover: The origin story of Five Lives and the motivation behind focusing on dementia and cognitive decline. The demographics benefitting from using Five Lives Gamifying behaviour change Evidence generation and funding journey The advantages of direct-to-consumer distribution through the app store How digital therapeutics can fit within the NHS The challenges of implementing DTx across UK, French, and German markets Guest Links and Resources: Connect with Sylvain Piquet on LinkedIn Visit www.fivelives.health Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In honor of Gift of Sight month we're replaying this insightful episode with Mark Wuttke, CEO of Dopavision. In their own words, Dopavision is pioneering the development of innovative solutions that target the eye's innate dopamine pathway to address unmet needs in ophthalmology using digitally delivered light.  Topics include: The background to Dopavision The pediatric Myopia vs adult Myopia markets Patient experience using Dopavision Changes to clinical trials and the mechanism of action Plans for commercialization Potential future applications to other ophthalmological conditions and neurological conditions  The future of OTC vs Rx Guest Links and Resources: Connect with Mark Wuttke on LinkedIn Visit Dopavision Listen to Digital Therapeutics for Pediatrics, Oncology and Managing Pain with Francesca Wuttke Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Vijay Ravindran, founder and CEO of Floreo. Floreo allows therapy to be more engaging and happen anywhere, assisting people in practicing critical social skills at their own pace through immersive experiences, starting with adolescent Autism spectrum disorder. In this episode, we cover: The founding story of Floreo Market for autism and neurodiversity The child and caregiver experience using Floreo Funding journey and key milestones User and caregiver experience using Floreo Scientific hypothesis and evidence generation journey Scaling virtual reality in healthcare Guest Links and Resources: Connect with Vijay Ravindran on LinkedIn Visit floreovr.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

We're seeing a broader consolidation of digital health solutions this year to bring together the amazing talent and the scientifically validated assets to drive scale in the market and improve unit economics. On the heels of last week's announcement of the merger between Fern Health and BehaVR tune into this replay episode to hear Eugene Borukhovich's conversation with Aaron Gani, Founder and CEO of BehaVR. BehaVR translates proven science into immersive and engaging XR therapeutics for mental and behavioral health. In this episode, we cover: Origin Story: Aaron Gani shares the origin story of BehaVR, starting from its inception in 2016 and the inspiration behind creating immersive XR therapeutics for mental and behavioral health. Funding Journey and Milestones: Walk through BehaVR's funding journey, uncovering the key milestones achieved with each funding round and how it has shaped the company's growth and impact in the digital therapeutics landscape. Patient Journey Using VR: Gain insights into the end customer experience offered by BehaVR, highlighting the effectiveness of immersive therapeutics in supporting mental well-being. Scientific Hypothesis and Evidence Generation: Explore the hypothesis that BehaVR is built upon and learn how their evidence generation journey is proving the effectiveness of their immersive XR therapeutics, showcasing the power of mind-body connections. Merging with OxfordVR and FDA Approval: Discover the decision-making process behind BehaVR's merger with OxfordVR and their journey towards FDA approval. Business Hypothesis and Scaling Plan: Delve into BehaVR's current business hypothesis and explore their scaling plan. Partnership with Sumitomo Dainippon: Aaron expands on BehaVR's partnership with Sumitomo Dainippon and discusses the commercial arrangement that led to this collaboration. Access to Care: Explore the accessibility of virtual reality therapy and its role in improving access to care for patients. Pear Therapeutics and the Future of PDTs: Aaron shares his thoughts on Pear Therapeutics and discusses the future of Prescription Digital Therapeutics (PDTs), providing insights into the evolving landscape of digital therapeutics and its potential to revolutionize mental health care. Guest Links and Resources: Connect with Aaron Gani on LinkedIn Visit BehaVR Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from, Rich Brancaccio, Chief Innovation Officer of Revibe Technologies, and Lindsay Ayearst, Chief Scientific Officer of Revibe Technologies. In their own words, Revibe is a digital therapeutics company fusing behavioral science with technology and currently developing a new digital therapy for ADHD. In this episode, we cover: Founding story and funding milestones Child and caregiver experience using Revibe Quantifying attention & capturing focus data Evidence generation journey & clinical endpoints The ADHD market choice to focus on adolescent ADHD Lessons learned from the first wave of similar products and companies OTC vs PDT Guest Links and Resources: Connect with Lindsay Ayearst on LinkedIn Connect with Rich Brancaccio on LinkedIn Visit www.revibetech.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

There are two kinds of people in the world, says Brent Vaughan — those who prefer to make incremental changes with a lower likelihood of failure, and those who aspire to fix (seemingly) intractable problems that have stymied others. Brent falls in the latter category. A serial entrepreneur, former venture capitalist, and current CEO of Cognito Therapeutics (a DTx company that specializes in neurodegenerative diseases), Brent is also uniquely positioned to evaluate the future of next generation digital therapeutics. Brent and Eugene talk about the differences between prescription and business-to-consumer DTx, the importance of engaging patients and users early on in the development of novel products, and the exciting potential of translational DTx solutions. Eugene's podcast partner, Brian Dolan, also pops in with a question. Guest Links and Resources: Connect with Brent Vaughan: LinkedIn Visit Cognito Therapeutics: Twitter | LinkedIn | Facebook | Website Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Chan Yoon, MD, CEO of EverEx. EverEx is revolutionizing musculoskeletal rehabilitation with cutting edge AI, pose estimation technology, and evidence based treatments. In this episode, we cover: Insights into Digital Health in South Korea The EverEx creation journey The musculoskeletal health market in South Korea  Funding journey and challenges in the market Reimbursement environment in South Korea Entering the US Market with the product EverEx Rehab Clinical trials and patient experience using EverEx products Guest Links and Resources: Connect with Chan Yoon on LinkedIn Visit Everex.kr Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

Cognitive behavioral therapy (CBT) is an evidence-based form of therapy that has been in use for decades. My guest in this episode believes that CBT can be applied to create better therapeutics, and, in fact, that's exactly what his company is called: Better Therapeutics. Dr. Mark Berman, the Chief Medical Officer at Better Therapeutics, explained that the goal of CBT is to “help people change some of those core beliefs, which then directly influence what we do on a day to day basis.” And while CBT was originally applied to help people with conditions like PTSD, anxiety and depression, the team at Better Therapeutics have developed their own variant of CBT to apply the core principles of CBT to the ideas that drive root behaviors like diet, exercise and other supportive lifestyle behaviors. Tune into this episode to hear how Better Therapeutics are creating new digital treatments to reverse the progression of cardiometabolic disease, improve quality of life and inform clinical decisions. In this episode, we cover: Patient experience using digital therapeutics for type 2 diabetes Nutritional CBT – Better Therapeutics innovative new form of Cognitive Behavioral Therapy Why companies are opting to create Prescription Digital Therapies rather than self-managed lifestyle apps What's next in the Better Therapeutics pipeline and how these decisions are made The future of Digital Therapeutic infrastructure Guest Links and Resources: Connect with Mark Berman on LinkedIn | Twitter Visit bettertx.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Season 2 of Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Francesca Wuttke, Founder and CEO of Nen who is focusing on building prescription digital therapeutic at a cross-section of pediatrics, pain with an initial focus in oncology. In this episode, we cover: The background to nen and naming the company Gamifying CBT for treating children's pain Targeting the psychological aspects of pain Treating unmet needs in oncology Patient and parent experience Clinical evidence generation and PDT Business hypothesis, market entry, pricing and reimbursements Guest Links and Resources: Connect with Francesca Wuttke on LinkedIn Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Season 2 of Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

Curio has announced positive data from the Supporting Maternal Mental Health and Emotional Regulation (SuMMER) trial demonstrating that MamaLift Plus has met its efficacy endpoints. This is a significant step towards providing better support for mothers during a crucial time.  In this Replay episode we hear from Shailja Dixit, CEO of Curio. In their own words: 'Curio is a Digital Therapeutics company with tailor-made Cognitive Behavioral Therapy programs for Women across the cycle of life – encompassing age groups, physiological conditions and social settings'. Topics include: The Founding Story of Curio Using Digital to Destigmatize Mental Health Support User experience of the MamaLift product Combining methods of Cognitive Behavioural Therapy, Interpersonal Therapy and Behavioural Activation Therapy  PDT vs Physician recommended DTx  Guest Links and Resources: Connect with Shailja Dixit on LinkedIn Visit https://www.curiodigitaltx.com/ Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Sponsors: Akili | LSI | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this special feed drop hear Eugene Borukhovich in conversation with Pharmaphorum Editor in Chief Jonah Comstock discussing what they saw and heard at DTx East in Boston. This year the digital therapeutics space took a hit with the downfall of Pear Therapeutics, one of the most well-known of the industry's still-active pioneers. Combined with Akili Interactive's hard pivot to OTC , some in the industry are wondering whether standalone prescription digital therapeutics are a failed experiment. Pharmaphorum Links and Resources: Connect with Jonah Comstock on LinkedIn Visit pharmaphorum.com Episode Write Up Pharmaphorum Podcast DTx Podcast Links and Resources:: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Mark Wuttke, CEO of Dopavision. In their own words, Dopavision is pioneering the development of innovative solutions that target the eye's innate dopamine pathway to address unmet needs in ophthalmology using digitally delivered light.  Topics include: The background to Dopavision The pediatric Myopia vs adult Myopia markets Patient experience using Dopavision Changes to clinical trials and the mechanism of action Plans for commercialization Potential future applications to other ophthalmological conditions and neurological conditions  The future of OTC vs Rx Guest Links and Resources: Connect with Mark Wuttke on LinkedIn Visit Dopavision Listen to Digital Therapeutics for Pediatrics, Oncology and Managing Pain with Francesca Wuttke Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Andrew Jenkinson and Niall O'Driscol, CEO's and Co-founders of vStream. vStream's primary focus is on the creation of compelling and engaging patient-centric experiences. Specializing in virtual reality, augmented reality, mixed reality, 360 video, immersive experiences, and digital installations Topics include: The background to vStream and the product ShineVR The funding journey Competition and the overall market in virtual reality Patient experience using ShineVR incorporating proven CBT techniques in a number of different spaces Scientific hypothesis and evidence generation process The proposition to employers for for corporate wellness Scaling plan and future pipeline Insights from a patient using ShineVR Guest Links and Resources: Connect with Niall O'Driscoll on LinkedIn Connect with Andrew Jenkinson on LinkedIn Visit vStream Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

If you've been keeping up with the news you'll know that since March this year, Kranus Edera has been permanently listed as a digital health application by the Federal Institute for Drugs and Medical Devices. But the journey did not stop there. Last week Kranus Health achieved another milestone: successful price negotiations with the GKV-Spitzenverband, which is in charge of negotiating the reimbursement amount for new medications from pharmaceutical manufacturers. Kranus Edera has now secured one of the highest permanent reimbursement prices ever recorded for a DiGA in Germany: €235 (incl. VAT). To provide some context for this exciting development we're revisiting our episode with Jens Noertershaeuser, Founder & Co-CEO of Kranus Health. In their own words, Kranus Health's mission is to revolutionize men's health by providing innovative and accessible healthcare solutions. As one of only 10 companies with a permanent approval, Kranus Edera is the only the first digital health app (DiGA) for the treatment of erectile dysfunction. In this episode, we cover: The background to Kranus Health The focus on men's health and erectile dysfunction as a flagship product Products in development and the future of Kranus Health The funding journey Patient experience using the product Evidence generation and the DiGA process Insurance company reimbursment Guest Links and Resources: Connect with Jens Noertershaeuser on LinkedIn Visit kranushealth.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Meri Beckwith, Co-founder of Lindus Health. In their own words, Lindus delivers end to end clinical trials for health tech and biotech pioneers. Topics include: The background and inception story of Lindus Health Lindus Health's place in the value chain Key funding milestones and achieving in a difficult market enviroment The unique aspects of clinical trials for DTx DTx as a medical device Pharmaceutical cclients in the DTx market The future for clinical trials and digitization Guest Links and Resources: Connect with Meri Beckwith on LinkedIn Visit Lindus Health Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Susa Monacelli, General Manager at Propeller Health. In their own words Propeller Health is a precision digital health company on a mission to uplift every person living with chronic disease so they can take control of their health and live a better life. Topics include: The background to Propeller Health and the ResMed umbrella The original business hypothesis of ResMed and how this has evolved Patient experience using Propeller Health Differentiating propositions to health system, pharma and payers DTx vs. Disease Management 2.0 The future of prescription digital therapeutics Partnerships with health systems vs other routes to patient access Challenges holding the digital health industry back Guest Links and Resources: Connect with Susa Monacelli on LinkedIn Visit Propeller Health Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

Have you heard? On August 22, Mahana Therapeutics announced a distribution and marketing partnership with Bayer's consumer health division. This partnership unites Mahana's proficiency in digital therapeutic advancement with Bayer's commitment to empowering individuals through cutting-edge digital solutions, all aimed at enabling greater personal health control. The full press release is linked below. In light of this, we're bringing you this replay episode with Simon Levy, CEO and Co-founder, and Ann Montgomery, Chief Product Officer at Mahana. In their own words, Mahana develops digital treatments for people living with chronic health conditions, and their first treatment, Mahana for IBS, is now available as an FDA-cleared app. In this episode, we cover: The founding story and funding journey of Mahana Complexities of the end to end patient experience The freemium model and how that translates into a PDT Evidence generation and FDA clearance process Scaling plans for PDTs Guest Links and Resources: Press Release about the Mahana and Bayer partnership Connect with Simon Levy on LinkedIn Connect with Ann Montgomery on LinkedIn Visit Mahana.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Brian Wallace, CMO and Co-Founder of Calmsie. Calmsie in their own words are empowering children to develop emotional resilience from an early age. Calmsie creates engaging DTx video games designed to improve outcomes for children with depression and anxiety. In this episode, we cover: Translating addiction science to treat depression and anxiety in children The origin story and funding journey to Calmsie Parent and child experiences using the gamified program Emotional resilience training for prevention of mental health issues How the Calmsie video game affects the brain Evidence generation and deciding on PDT vs non-PDT routes The free workbook helping children understand the war in Ukraine Guest Links and Resources: Connect with Brian Wallace on LinkedIn Visit calmsie.ai YourCoach Health: Deep Dive Into Adolescent Health Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this special feed drop hear the first episode of Emerging Medtech Today, hosted by Henry Peck and powered by LSI. The Emerging Medtech Today podcast offers a unique opportunity to gain valuable insights from industry leaders who are building breakthrough businesses that are moving medtech forward. Join Henry as he engages in captivating conversations with innovators and investors who are at the forefront of medtech. Discover the strategies, technologies, and ideas that are shaping the future of healthcare.  In this episode Henry Peck speaks with Diana Saraceni and Alessio Beverina, co-founders and managing directors of Panakes, a venture capital firm that's helping to build the next generation of game-changing technologies companies in the field of Life Sciences. Diana brings 23 years of venture capital experience and previously co-founded another successful venture capital firm called 360 Capital. Alessio, with an engineering background, co-founded Panakes in 2015 after working as a research engineer at Sofinnova Partners. Throughout the episode, Diana and Alessio provide valuable insights into the evolving landscape of medtech investing, shedding light on the complexities, challenges, and opportunities in the field. Topics include: Current market conditions and challenges faced by companies in medtech Key learnings from Panakes' first fund which focused on medtech and raised €75 million Strategies for the newly raised second fund, with plans to expand its focus to include biotech and opportunities where medtech and biotech converge The impact of regulatory changes, particularly the MDR (Medical Device Regulation) shift and the increasing prioritization of FDA approval in Europe   Navigating the evolving landscape of digital health and its intersection with artificial intelligence (AI) Health tech and digital health opportunities in Europe compared to the US A reflection on the future of healthcare innovation Diana and Alessio's upcoming participation at the LSI Europe ‘23 conference in September, where they will discuss these topics in greater detail And more! Transcript of episode Guest links and resources: Connect with Diana Saraceni: LinkedIn Connect with Alessio Beverina: LinkedIn | Twitter Panakes Connect with Henry: Twitter | LinkedIn Learn more about LSI Sign up for LSI Europe '23 Connect with LSI: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Connect with Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from David Kim, Managing Director at DigiTx Partners. In their own words DigiTX Partners is a venture firm focused on investing in and supporting supporting early stage startup companies in the digital health space. Launched in 2016 as a joint venture by Astellas Pharma And MPM Capital, DigiTx Partners remains one of a few venture funds exclusively dedicated to the digital health space. In 2018, Astellas continued its endeavor in digital health by forming the Rx Plus Digital Fund with DigiTx Partners as its investment manager. In this episode, we cover: What are the challenges faced by digital therapeutics in terms of distribution and clinical workflow? What hypothesis does DigiTx on DTx? What are the benefits of standalone vs drug+? Are DigiTx tracking any other modalities? What lessons have DigiTx learned so far? What will be the drivers for new capital injections in DTx especially? What are investors looking for ? What will the drivers of success going forward be for DTx?  How will the role of doctors, nurse & pharmacists change in order for the industry overall to scale PDT's? Guest Links and Resources: Connect with David Kim on LinkedIn Visit DigiTx Partners Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Sean Khozin, Senior Partner at the investment firm Braven Partners. He focuses on advancing in innovations at the intersection of biology, technology and AI. Sean was previously the CEO of CancerLinQ and the Global Head of Data Strategy and Data Science at Johnson & Johnson. He had a successful tenure in the US federal government as the associate director of FDA's Oncology Center of Excellence and the founding executive director of FDA INFORMED, a data science and technology incubator he established under special authorities from the US department of health and human services. Topics include: How are Braven Partners incubating and supporting minimally viable ecosystems of companies that can make a difference? What are the goals of the Alliance for Artificial Intelligence in Healthcare? How can digital therapeutics developers ensure effective reimbursement for their products in the healthcare industry? How is the ethos of AI in healthcare speaking to a culture that is focused on safety without compromising innovation? How do we demystify new tools and technologies such as AI? How does the FDA think about regulating AI? What can digital therapeutic manufacturers companies, entrepreneurs and trailblazers learn from the Alliance for Artificial Intelligence in Healthcare (AAIH)? Guest Links and Resources: Connect with Sean Khozin on LinkedIn Visit Braven Partners Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Benjamin Alouf, MD, Chief Medical Officer at Limbix. In their own words, Limbix is the first digital therapeutic for adolescent depression.  Big Health, the leading provider of non-drug digital treatments for mental health, has now acquired Limbix. In addition to health care providers, SparkRx will be made available to Big Health's employer, public sector, health systems and health plan customers, and through the company's strategic distribution agreements with pharmacy benefit managers (PBMs), significantly increasing nationwide access. In this episode, we cover: Origin of the company and story behind the name 'Limbix' The funding journey and key milestones achieved The choice to focus on the young adult population in particular Patient experience with SparkRx Defining good patient engagement in adolescent mental health Evidence generation and FDA submission process Business hypthothesis and scaling plan The future of the PDT market Guest Links and Resources: Connect with Benjamin Alouf, MD on LinkedIn Visit Limbix.com Episode PDF Big Health Expands into Adolescent Mental Health Through Acquisition of Limbix Host Links: Eugene Borukhovich: Twitter | LinkedIn Chandana Fitzgerald, MD: Twitter | LinkedIn YourCoach.health: Website | Twitter Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Eddie Martucci, co-founder and CEO of Akili. In their own words, Akili Interactive is a leading digital health company combining scientific and clinical rigor with ingenuity of the tech industry to reinvent medicine. In this episode, we cover: What factors have led to the increase in market demand for non-drug treatments for adult ADHD? How does Akili Interactive's prescription video game product, EndeavorRx, differ from traditional behavioral therapy for ADHD? What are the advantages and challenges of developing a digital therapeutic product that is available over-the-counter (OTC) without a prescription? How does the insurance coverage landscape impact the availability and adoption of digital therapeutics? What strategies does Akili Interactive employ to address the lack of awareness about digital therapeutics and their potential benefits? How does the user interface and experience of the EndeavorRx companion app, EndeavorRx Insight, contribute to higher compliance and better outcomes for families? How has Akili Interactive adapted and improved their commercial platform for scaling the distribution of their products? What advice does Eddie Martucci have for health executives? Guest Links and Resources: Connect with Eddie Martucci on LinkedIn Visit Akili Season 1 Episode: Akili's Revolutionary Digital Therapeutic with Eddie Martucci Co-Founder/CEO of Akili Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

Let's face it, entrepreneurship is tough. While we're certainly seeing a much needed correction in the market this does not make it easier for any trailblazers out there. Sales cycles have slowed down. Decision making became even less transparent. And finally, funding became a numbers game. Now add to all of this, some recent bankruptcies and your head starts spinning. So what should a Digital Therapeutics entrepreneur do? Since we have the pleasure of hosting dozens upon dozens of leaders in the industry, we decided to put together a special episode with their advice to the awesome entrepreneurs out there. Guest Links and Resources: Connect with Acacia Parks on LinkedIn Visit Liquid Amber Connect with Ameya Phadke, Ph.D on LinkedIn Visit Chiesi Group Connect with Omar Manejwala, MD on LinkedIn Visit Dario Health Connect with Benjamin Alouf, MD on LinkedIn Visit Limbix Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jennifer Goldsack, CEO of Digital Medicine Society (DiMe). In their own words, DiMe is a global non-profit and the professional home for all members of the digital medicine community. In this episode, we cover: The origin and mission of DiMe Defining digital health, digital medicine and digital therapeutics Collaborating with the Digital Therapeutics Alliance Stakeholder management for patients and pharma The payer contracting framework Working across the healthcare ecosystem DiMe's approach to the science behind digital medicine and digital measurement products Guest Links and Resources: Connect with Jennifer Goldsack on LinkedIn Visit dimesociety.org Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Joe Perekupka, CEO of Freespira. In their own words Freespira is 'the only medication-free, FDA-cleared digital therapeutic treatment proven to significantly reduce or eliminate symptoms of panic disorder, panic attacks and post-traumatic stress disorder in just 28 days.' In this episode, we cover: The founding story of Freespira The user experience from prescription to daily use The role of health coaches within Freespira Identifying potential candidates for Freespira The current landscape for panic disorder treatment and research into MDMA-assisted therapies Evidence generation to FDA approval journey Evolving pricing models The scope of PTSD across the US Guest Links and Resources: Connect with Joseph Perekupka on LinkedIn Visit freespira.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, Eugene sits down with Megan Coder, Chief Policy Officer of the Digital Therapeutics Alliance (DTA). Tune in to hear the exciting and positive advancements taking place in the digital therapeutics industry following the DTA Inaugural Summit. Topics include: The success of DTA's first summit in Washington DC Introducing a new definition of DTx The new DTx Evalution Toolkit Developing the new European DTx Policy Report in partnership with Healthware Guest Links and Resources: Connect with Megan Coder on LinkedIn Visit dtxalliance.org Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: LSI | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jenna Carl PhD, Chief Medical Officer at Big Health. Big Health believes in mental health care for all and that their digital therapeutics are safe and effective non-drug options for mental health. In this episode, we cover: Consumer Experience with Sleepio vs Daylight: Gain insights into the end consumer experience and how these solutions are designed to improve sleep and mental well-being. Go-to-Market Strategy: Explore Big Health's go-to-market strategy, and activating employers to reach upstream employees and achieve high engagement rates. Deep Dive into the Relationship with CVS: Gain a deeper understanding of Big Health's relationship with CVS, specifically regarding medication targeting. Abandoning Direct-to-Consumer (DTC): Uncover the reasons behind Big Health's decision to shift away from a direct-to-consumer approach and explore the implications of this strategic shift. Clinical Evidence and Decision-making Processes: Learn about Big Health's extensive clinical study basis and the rationale behind this approach. Future Product Pipeline: Gain insights into Big Health's future plans for additional products and the exciting developments in their pipeline. Big Health and Pear's Differing Go-To-Market Strategies: Explore the differing go-to-market routes between Big Health and Pear Therapeutics Stand-alone DTx vs. Disease Management 2.0: Understand the merits and challenges of stand-alone digital therapeutics versus disease management 2.0 Guest Links and Resources: Connect with Jenna Carl on LinkedIn Visit BigHealth.com Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, Eugene Borukhovich sits down with Aaron Gani, Founder and CEO of BehaVR. BehaVR translates proven science into immersive and engaging XR therapeutics for mental and behavioral health. In this episode, we cover: Origin Story: Aaron Gani shares the origin story of BehaVR, starting from its inception in 2016 and the inspiration behind creating immersive XR therapeutics for mental and behavioral health. Funding Journey and Milestones: Walk through BehaVR's funding journey, uncovering the key milestones achieved with each funding round and how it has shaped the company's growth and impact in the digital therapeutics landscape. Patient Journey Using VR: Gain insights into the end customer experience offered by BehaVR, highlighting the effectiveness of immersive therapeutics in supporting mental well-being. Scientific Hypothesis and Evidence Generation: Explore the hypothesis that BehaVR is built upon and learn how their evidence generation journey is proving the effectiveness of their immersive XR therapeutics, showcasing the power of mind-body connections. Merging with OxfordVR and FDA Approval: Discover the decision-making process behind BehaVR's merger with OxfordVR and their journey towards FDA approval. Business Hypothesis and Scaling Plan: Delve into BehaVR's current business hypothesis and explore their scaling plan. Partnership with Sumitomo Dainippon: Aaron expands on BehaVR's partnership with Sumitomo Dainippon and discusses the commercial arrangement that led to this collaboration. Access to Care: Explore the accessibility of virtual reality therapy and its role in improving access to care for patients. Pear Therapeutics and the Future of PDTs: Aaron shares his thoughts on Pear Therapeutics and discusses the future of Prescription Digital Therapeutics (PDTs), providing insights into the evolving landscape of digital therapeutics and its potential to revolutionize mental health care. Guest Links and Resources: Connect with Aaron Gani on LinkedIn Visit BehaVR Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode of DTx Podcast, Eugene Borukhovich sits down with Acacia Parks, Founder of Liquid Amber Consulting. Liquid Amber helps digital health and DTx companies support the claims they want to make using scientific evidence, in the ways that will be compelling to the audiences they care about. Topics include: A Day in the Life of a Chief Science Officer: Gain insights into the role of a Chief Science Officer before Acacia Parks ventured into her own entrepreneurial journey, and get a glimpse into the challenges and responsibilities involved in the position. Liquid Amber: Uncover the story behind the name "Liquid Amber" and explore the mission and vision of the company. Evidence Generation Process: Dive deep into the process of setting up the right processes and PDT vs non PDT. Active Ingredients in DTx: Discover how active ingredients play a crucial role in both molecular-based and software-based interventions. Pro Tips for Regulatory Approvals: Acacia Parks shares her expert advice on getting regulatory approvals for DTx. Learn what companies should do before, during, and right after the regulatory process to streamline the approval journey. Being a Patient on Freespira: Get a firsthand perspective as Acacia Parks walks us through her personal experience using Freespira. Guest Links and Resources: Connect with Acacia Parks on LinkedIn Visit liquidamber.consulting Episode PDF Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode Eugene Borukhovich sits down with Ameya Phadke, Ph.D., Patient Non-Pharma Solutions Leader at Chiesi Group. Join them as they delve into the world of digital therapeutics and explore how pharma companies are embracing digital health to revolutionize patient care. Topics include: The Chiesi Group's History: Discover the largest international pharmaceutical Group certified as a B Corp, with a rich history spanning over 80 years, and their focus on respiratory diseases, special care, and rare diseases. Pharma Moving into the Digital Health Space: Gain insights into how Chiesi Group recognized the need to go beyond medications to deliver impactful outcomes for patients, leading them to explore the digital therapeutics field. The Kaia Deal: Learn about Chiesi's partnership with Kaia and their shared vision to address the access gap in pulmonary rehabilitation through digital solutions, exemplifying the power of collaboration and building something impactful together. Standalone Digital Therapeutics vs. Disease Management: Understand the importance of both standalone digital therapeutics and disease management platforms in the patient journey, with each serving unique purposes and addressing different aspects of care. Chiesi's Partnership with Aptar: Explore Chiesi's collaboration with Aptar, aiming to make disease management practices more accessible to patients by bringing services to their fingertips, ultimately empowering patients and enhancing respiratory care. Challenges of Drug+: Reflect on the challenges and opportunities that arise when combining digital therapeutics with pharma, including the need to align the mechanism of action with desired outcomes and the importance of identifying viable use cases. The Future of DTx after Pear Therapeutics: Gain insights into the evolving digital therapeutics landscape and the enduring mission of Chiesi Group and other companies to leverage digital solutions to improve patient lives, regardless of market trends. Guest Links and Resources: Connect with Ameya Phadke on LinkedIn Visit www.chiesi.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jens Noertershaeuser, Founder & Co-CEO of Kranus Health. In their own words, Kranus Health's mission is to revolutionize men's health by providing innovative and accessible healthcare solutions. As one of only 10 companies with a permanent approval, Kranus Edera is the only the first digital health app (DiGA) for the treatment of erectile dysfunction. In this episode, we cover: The background to Kranus Health The focus on men's health and erectile dysfunction as a flagship product Products in development and the future of Kranus Health The funding journey Patient experience using the product Evidence generation and the DiGA process Insurance company reimbursment Guest Links and Resources: Connect with Jens Noertershaeuser on LinkedIn Visit kranushealth.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Omar Manejwala, MD, Chief Medical Officer at DarioHealth. In their own words, DarioHealth makes it easy for people to care for their health, with continuous and connected support that anticipates needs, understands motivation, and simplifies behavior change to put better health and outcomes in everyone's reach. In this episode, we cover: The history of DarioHealth DTx vs disease management The future of PDTs Patient/customer experience using DarioHealth The pipeline to adding different therapeutic areas Clinical differentiation from competitors Clinical trials and evidence generation DarioHealth's relationship with Sanofi Guest Links and Resources: Connect with Omar Manejwala on LinkedIn Visit dariohealth.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Alberta Spreafico, Global Head of Digital Health & Innovation Strategy at Healthware Group. In their own words, Healthware combines advisory, agency services and technology capabilities to improve health outcomes while delivering transformational business results. In this episode, we cover: The background to Healthware VR Therapies with Orion Pharma Scaling challenges across the EU The DTx landscape in Italy Healthwares partnership with the Digital Therapeutics Alliance The future of PDT's Guest Links and Resources: Connect with Alberta Spreafico on LinkedIn Visit healthwaregroup.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jennifer Goldsack, CEO of Digital Medicine Society (DiMe). In their own words, DiMe is a global non-profit and the professional home for all members of the digital medicine community. In this episode, we cover: The origin and mission of DiMe Defining digital health, digital medicine and digital therapeutics Collaborating with the Digital Therapeutics Alliance Stakeholder management for patients and pharma The payer contracting framework Working across the healthcare ecosystem DiMe's approach to the science behind digital medicine and digital measurement products Guest Links and Resources: Connect with Jennifer Goldsack on LinkedIn Visit dimesociety.org Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Benjamin Alouf, MD, Chief Medical Officer at Limbix. In their own words, Limbix is the first digital therapeutic for adolescent depression. In this episode, we cover: Origin of the company and story behind the name 'Limbix' The funding journey and key milestones achieved The choice to focus on the young adult population in particular Patient experience with SparkRx Defining good patient engagement in adolescent mental health Evidence generation and FDA submission process Business hypthothesis and scaling plan The future of the PDT market Guest Links and Resources: Connect with Benjamin Alouf, MD on LinkedIn Visit Limbix.com Host Links: Eugene Borukhovich: Twitter | LinkedIn Chandana Fitzgerald, MD: Twitter | LinkedIn YourCoach.health: Website | Twitter Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Andrzej Jończyk, MD, Co-founder and CEO USA of Prosoma. In their own words, Prosoma develops a portfolio of digital therapeutic medical software products that cover the entirety of behavioral treatment needs of cancer patients. In this episode, we cover: The background to Prosoma The funding journey and milestones reached Patient experience using Prosomo's Living Well product How Living Well is personalized specifically for women living with cancer Evidence generation and journey to PDT & DiGA Engagement levels in the technology Commercial traction across Europe and expansion into the USA Guest Links and Resources: Connect with Andrzej Jończyk, MD on LinkedIn Visit Prosoma.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jason Kahn, Co-founder and Chief Science Officer at Mightier. Mightier, in their own words, is a digital program for kids that uses their heart rate to teach coping skills through game-based play. In this episode, we cover: The founding story and meaning behind the name 'Mightier' Funding journey and key milestones in bringing the product to market Child and parent experience using Mightier The total addressable market for DTx in pediatric behavioral health The mechanism of action and the underlying technology utilized in Mightier Working with gaming companies Evidence generation and RCTS PDT's vs DTC's Guest Links and Resources: Connect with Jason Kahn on LinkedIn Visit Mightier Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Bayer G4A | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode we hear from Simon Levy, CEO and Co-founder, and Ann Montgomery, Chief Product Officer at Mahana. In their own words, Mahana develops digital treatments for people living with chronic health conditions, and their first treatment, Mahana for IBS, is now available as an FDA-cleared app. In this episode, we cover: The founding story and funding journey of Mahana Complexities of the end to end patient experience The freemium model and how that translates into a PDT Evidence generation and FDA clearance process Scaling plans for PDTs Guest Links and Resources: Connect with Simon Levy on LinkedIn Connect with Ann Montgomery on LinkedIn Visit Mahana.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this special episode of DTx Podcast, Eugene is joined by Brent Vaughan, CEO of Cognito, as well as industry leaders from previous episodes, to weigh in on the recent Pear Therapeutics news and the future of prescription digital therapeutics. In this episode, we cover: The impact on the PDT market Future efforts to move DME to PDT The impact on the entrepreneurs currently developing PDT's Predictions on the future of Pear Therapeutics Reflections on the history and future of DTx from Chris Bergstrom (Amalgam RX), David Klein (Click Therapeutics), Andy Molnar (DTA), Sammeli Liikkanen (Orion), Francesca Wuttke (nen), Andrzej Jonczyk (Prosoma), Steve Driver (Advocate Health) and Grady Hannah (NightWare) Join the HealthXL platform for free today and be the first to read their analysis of Pear's predicament and what it means for the DTx industry: https://portal-beta.healthxl.com/?s=2fb5 Guest Links and Resources: Connect with Brent Vaughan on LinkedIn Connect with Chris Bergstrom on LinkedIn Connect with David Klein on LinkedIn Connect with Andy Molnar on LinkedIn Connect with Sammeli Liikkanen on LinkedIn Connect with Francesca Wuttke on LinkedIn Connect with Andrzej Jonczyk on LinkedIn Connect with Steve Driver on LinkedIn Connect with Grady Hannah on LinkedIn Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Josh Sackman, President and Co-founder of AppliedVR. AppliedVR, in their own words, provide virtual reality-based treatments that represent a comprehensive approach to chronic pain that empowers patients with accessible digital tools self-managed in their own home. In this episode, we cover: The origin story of AppliedVR Transitioning from an app store for health VR to focus pain management market Patient experience and the pain management pipeline Funding journey and key funding milestones The scientific hypothesis of "mind over matter" behind AppliedVR's approach and evidence generation journey The FDA approval process for AppliedVR and lessons learned for entrepreneurs. AppliedVR's current business hypothesis and scaling plan Market channels and scaling VR Guest Links and Resources: Connect with Josh Sackman on LinkedIn Visit www.appliedvr.io Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Jo Masterson, CEO and Co-Founder of 2Morrow. In their own words 2Morrow's mission is to help millions improve their lives with the use of evidence-based, behavioral change programs. In this episode, we cover: The founding philosophy of 2Morrow and co-founding a company with your partner The funding journey The NIH grant for 2Morrow's program for pain Using a DTx to cope with pain that will not be effected by behaviour change Consumer experience using different 2Morrow programs Core principles of acceptance, awareness and mindfulness Evidence generation and approach to market Guest Links and Resources: Connect with Jo Masterson on LinkedIn Visit www.2morrowinc.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Brian Wallace, CMO and Co-Founder of Calmsie. Calmsie in their own words are empowering children to develop emotional resilience from an early age. Calmsie creates engaging DTx video games designed to improve outcomes for children with depression and anxiety. In this episode, we cover: Translating addiction science to treat depression and anxiety in children The origin story and funding journey to Calmsie Parent and child experiences using the gamified program Emotional resilience training for prevention of mental health issues How the Calmsie video game affects the brain Evidence generation and deciding on PDT vs non-PDT routes The free workbook helping children understand the war in Ukraine Guest Links and Resources: Connect with Brian Wallace on LinkedIn Visit calmsie.ai Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Sylvain Piquet, COO and Co-founder of Five Lives, the app that leverages the new science of brain aging, neuroplasticity, and cognitive reserve to help people improve their brain health and prevent cognitive decline and dementia. In this episode, we cover: The origin story of Five Lives and the motivation behind focusing on dementia and cognitive decline. The demographics benefitting from using Five Lives Gamifying behaviour change Evidence generation and funding journey The advantages of direct-to-consumer distribution through the app store How digital therapeutics can fit within the NHS The challenges of implementing DTx across UK, French, and German markets Guest Links and Resources: Connect with Sylvain Piquet on LinkedIn Visit www.fivelives.health Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Hannes Klöpper, CEO of HelloBetter. HelloBetter, in their own words, wants to empower as many people as possible to manage their own mental health and improve their quality of life – anywhere and at any time, without the wait lists. In this episode, we cover: The origin story of HelloBetter, from university research to becoming a digital therapeutic. Structuring a DTx into accessible and consumable courses The patient journey, from receiving a prescription to activating and using the platform. The DiGA process: evidence, benefits and commercialization The reaction of EU vs US investors Guest Links and Resources: Connect with Hannes Klöpper on LinkedIn Visit hellobetter.de Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Contributing Partners and Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health | Orion Pharma Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Joe Perekupka, CEO of Freespira. In their own words Freespira is 'the only medication-free, FDA-cleared digital therapeutic treatment proven to significantly reduce or eliminate symptoms of panic disorder, panic attacks and post-traumatic stress disorder in just 28 days.' In this episode, we cover: The founding story of Freespira The user experience from prescription to daily use The role of health coaches within Freespira Identifying potential candidates for Freespira The current landscape for panic disorder treatment and research into MDMA-assisted therapies Evidence generation to FDA approval journey Evolving pricing models The scope of PTSD across the US Guest Links and Resources: Connect with Joseph Perekupka on LinkedIn Visit freespira.com Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram

In this episode, we hear from Ali Hashemi, Co-founder of meta[bolic]. In their own words, meta[bolic] is a hybrid digital therapeutics company focused on addressing the global metabolic health crisis. In this episode, we cover: The initial business hypothesis of GluCare and meta[bolic] Digital therapeutics vs disease management Why we are becoming more metabolically unstable than previous generations The global metabolic problem Patient experience on the meta[bolic] platform Guest Links and Resources: Connect with Ali Hashemi on LinkedIn Visit Glucare.Health Host Links: Connect with Eugene Borukhovich: Twitter | LinkedIn Connect with Chandana Fitzgerald, MD: Twitter | LinkedIn Connect with YourCoach.health: Website | Twitter Check out Shot of Digital Health with Eugene and Jim Joyce: Website | Podcast App HealthXL: Website | Twitter | Join an Event Digital Therapeutics Podcast would not be possible without the support of leading DTx organizations. Thank you to: > Presenting Partner: Amalgam Rx > Sponsors: Akili | Big Health | Click Therapeutics | Lindus Health Follow Digital Health Today: Browse Episodes | Twitter | LinkedIn | Facebook | Instagram Follow Health Podcast Network: Browse Shows | LinkedIn | Twitter | Facebook | Instagram