Podcasts about bladder

In this episode of The Birth Trauma Mama Podcast, Kayleigh sits down with Danielle, a therapist and mother of three, to share a story that challenges the narrow ways we often define birth and postpartum trauma.Danielle's trauma did not occur during labor or delivery, it unfolded months postpartum, following what was supposed to be a routine surgical procedure to remove a fibroid. Instead, a cascade of medical complications led to a medical emergency, multiple surgeries, bladder injury, and an unplanned hysterectomy that permanently ended her ability to carry another pregnancy.Already navigating life with three young children, including a baby under one, Danielle suddenly found herself recovering from a major abdominal surgery, managing a catheter for weeks, and confronting the profound grief of losing her fertility without warning or choice.As both a therapist and a patient, Danielle brings a deeply reflective lens to this conversation, naming the invisible grief that so often accompanies medical trauma, especially when it doesn't “fit” neatly into recognized categories of loss.Together, Kayleigh and Danielle explore:

Dr. Allison Kendall is back on the podcast, and she brings with her a fascinating deep dive into a completely new approach to treating feline idiopathic cystitis (FIC). Yes—you read that right. Radiation therapy, traditionally reserved for oncology patients, is now being explored as a potential tool for one of the most frustrating and painful conditions our feline friends face. Dr. Kendall walks us through the rationale, the early clinical findings, and why this modality might just shift our entire perspective on chronic lower urinary tract disease in cats. It's innovative, surprising, and exactly the kind of boundary-pushing veterinary medicine we love to highlight. From there, we pivot smoothly (or as smoothly as you can pivot when discussing irritated bladders) into another urinary challenge: difficult stones. Dr. Kendall unpacks the diagnostic traps, the surgical dilemmas, and the metabolic mysteries behind those stubborn uroliths that refuse to behave. Expect practical tips, thoughtful insights, and a few “aha” moments that will make you rethink your approach to these cases in practice. Another great conversation with one of our favorite guests: equal parts science, clinical pearls, and inspiration for anyone who has ever managed a blocked cat at 3 a.m.Thanks for tuning in to the Purr Podcast with Dr. Susan and Dr. Jolle!If you enjoyed today's episode, don't forget to subscribe, rate, and leave us a review—it really helps other cat lovers and vet nerds find the show. Follow us on social media for behind-the-scenes stories, cat trivia, and the occasional bad pun. And remember: every day is better with cats, curiosity, and maybe just a little purring in the background. Until next time—stay curious, stay kind, and give your cats an extra chin scratch from us. The Purr Podcast – where feline medicine meets feline fun.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Svetlana: Hello, could you please talk about incomplete bladder emptying in females specifically? What is causing it and what can be done to fix it? Someone said that squatting over the toilet without sitting on it to urinate could cause it. Is that true? This is the need of having to urinate again within 15mins of going the first time with small amounts of volume and difficulty "pushing" it out. No infection symptoms.                                                                                                                          Eric: Hi Dr. C, thanks for all your efforts! I use melatonin (extended release) regularly to help w/ sleep. A recent large international study published on the News Medical Life Sciences website, and presented at the American Heart Association's 2025 Scientific Sessions, stated that long-term users of melatonin had a higher risk of heart failure, hospitalization, and even death compared to those who didn't take it. The study looked at more than 130,000 adults with chronic insomnia. This sounds crazy to me. Any thoughts about this? Thanks.                                                                                  Audrey: Hi Dr. Cabral, Is doing a coffee enema while breastfeeding safe? I know detoxes are not safe, but I wasn't sure if a coffee enema is different because the main reason is to increase glutathione                                                                                           Angie: Hi Dr. Cabral, My last job I worked, there were a lot of wireless devices and 5G networks. I noticed how easily drained I would feel and I didn't even work a full 8 hours. I have been dealing with chronic pain and fatigue off and on for years now, and recently have been more cautious of how often I use technology. I am now seeing the trend of products like grounding mats and functional silver infused garments. Can you talk about the connection between adrenal fatigue and EMF exposure? And the new EMF products that may potentially reduce exposure or make it bearable to work in a high-tech environment. Thank you so much for all your help and support that you and your team provides!!       Savannah: Is there any supplement/herb/product to help someone with gastroparesis? what about acid reflux too? i'm wondering what can help with natural stimulation of the stomach nerve/muscle contractions in order to have a bowel movement. i was told that i have slow gut motility & little to no peristalsis. the only thing that works for me is senna but it takes extreme higher dosages. i completed the cbo protocol and finisher and everything was better but now im chronically constipated & have been diagnosed with gastroparesis. i use to go everyday during the protocol but now i feel that ive lost the gut/brain communication too.. as i no longer go by myself as im laxative & enema dependent. any advice? thank you in advance.         Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3593 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Takeaways:Slimmer's Paralysis is a recognized condition.Ethical boundaries are crucial in patient relationships.Medical professionals must maintain professionalism at all times.Humor can sometimes arise in serious discussions.Patient stories should always be handled with care.The importance of clear communication in medical settings.Understanding patient experiences is vital for effective care.Ethics in medicine is a complex and nuanced topic.Medical discussions can lead to unexpected topics.Maintaining a professional demeanor is essential.   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Isaac is a medical-device innovator, entrepreneur, and the CEO & founder of Zida Therapeutics. He developed the Zida Control Sock, a wearable neuromodulation device intended to empower people living with urinary incontinence or overactive bladder to manage symptoms without relying solely on clinical  or pharmacalogical treatments.Isaac's passion for pelvic health comes from a deeply personal place. As he traced his family history, he learned his grandfather—who escaped Nazi Germany—struggled later in life with bladder control. That personal narrative sparked Isaac's mission: to create effective, noninvasive tools that can restore dignity and ease to the lives of those dealing with pelvic or bladder conditions.Under his leadership, Zida has secured FDA clearance for the Control Sock, and in early clinical use the device demonstrated ~80% “treatment success,” with meaningful reductions in urge incontinence and urinary frequency. Academically, Isaac holds a Master's in Technology Management, and professionally he's navigated the intersection of wearables, medical product development, and health tech start-ups. He's driven by the conviction that neuromodulation therapies should extend beyond clinic walls and into everyday life.Outside of his work with Zida, Isaac loves to spend time with his kids. https://livezida.com/https://www.facebook.com/p/Conquer-your-incontinence-ZIDA-control-sock-100064025981121/Thank you so much for listening! I use fitness and movement to help women prevent and overcome pelvic floor challenges like incontinence and organ prolapse. There is help for women in all life stages! Every Woman Needs A Vagina Coach! Please make sure to LEAVE A REVIEW and SUBSCRIBE to the show for the best fitness and wellness advice south of your belly button. *******************I recommend checking out my comprehensive pelvic health education and fitness programs on my Buff Muff AppYou can also join my next 28 Day Buff Muff Challenge https://www.vaginacoach.com/buffmuffIf you are feeling social you can connect with me… On Facebook https://www.facebook.com/VagCoachOn Instagram https://www.instagram.com/vaginacoach/On Twitter https://twitter.com/VaginaCoachOn The Web www.vaginacoach.comGet your Feel Amazing Vaginal Moisturizer Here

The boys are back! Barry Munro, John McAleavey, and Sasha Rabchevsky, three men with over 100 years of lived experience with spinal cord injury, have teamed up to share our knowledge on all things SCI related. Today's episode is dedicated to bladder management. We chronicle how each of us manages our situation (they're completely different), while also highlighting areas of need, concern, hope, and progress on the horizon, regarding this extremely important topic for the entire community.

Send us a textWelcome to Episode 2 of our Understanding Body Pain trilogy, where we explore how the lower body communicates through pain—and how Touch for Health and BioEnergetic Wellness can help you uncover the real root causes.In this episode, Dr. Michelle Greenwell is joined by Denise Cambiotti, HCD CIH BioEW, of www.muscletuners.ca and Kate Montgomery, HHP, ND as they guide you through the interconnected world of muscles, meridians, reflexes, tendons, ligaments, fascia, and posture. Pain rarely appears where it begins—plantar fasciitis, knee pain, hip tension, or ankle instability often stem from hidden imbalances that biofeedback can reveal.We begin by standing together and noticing the 9 points on the feet—a simple but powerful checkpoint for body alignment. Throughout the episode, you'll learn how the lower body compensates, how misalignment builds over time, and how muscle monitoring helps identify the true priority for healing.Topics We Explore:✨ How the lower-body meridians (including Bladder & Kidney) relate to muscle function✨ The role of gait patterns and how walking reveals hidden imbalances✨ How calf and foot tension are linked (including the deeper origin of plantar fasciitis)✨ Hip misalignment and its downstream effects on knees, ankles, and feet✨ Muscle monitoring for uncovering priority issues✨ Stories from clinical practice and athletic performance✨ Simple tools you can use today to restore balance

Get my FREE ebook, ‘Rebalancing Your Hormones Naturally.' Actionable strategies for immediate results! 

Joylux is is a proven at-home red light device for enhancing and revitalizing your vagina. If you're suffering from bladder leaks, vaginal dryness, or painful sex, this is an episode you don't want to miss. If you're read ing this on Black Friday, today is the ONE DAY of the year where they offer their highest discount: 25% off! Shop now!New episodes of Welcome to Wellness released every Friday!

Why do so many indoor cats develop urinary disease? Meet Dr. Allison Kendall, Associate Professor of Internal Medicine at NC State and feline nephrology & urology specialist. In this episode of Purr Podcast, we talk pee, pain, FIC, minimally invasive procedures, and why the bladder is just the beginning when it comes to cat urinary disease.Thanks for tuning in to the Purr Podcast with Dr. Susan and Dr. Jolle!If you enjoyed today's episode, don't forget to subscribe, rate, and leave us a review—it really helps other cat lovers and vet nerds find the show. Follow us on social media for behind-the-scenes stories, cat trivia, and the occasional bad pun. And remember: every day is better with cats, curiosity, and maybe just a little purring in the background. Until next time—stay curious, stay kind, and give your cats an extra chin scratch from us. The Purr Podcast – where feline medicine meets feline fun.

Why do we ignore the bladder… until the exact moment it refuses to be ignored? In this pre-Thanksgiving episode, Dr. Stephanie Hack is joined by expert urogynecologist Dr. Charelle Carter-Brooks to break down the bladder symptoms that sneak up on women during perimenopause, postpartum, and the busy midlife years. They talk urgency, leaks, “mom jumps,” nighttime peeing, and the pelvic floor habits we were never taught — including the surprising thing most women do on the toilet that actually makes their symptoms worse. If you've ever wondered, “Is this normal?” this episode is your clarity.

Wound care is an important part of recovery for patients with neurogenic bladder undergoing complex lower urinary tract surgery. In this episode, Madison Hughes talks with Dr. Kyle Rove and Dr. Kelly Harris, pediatric urologists at Children's Hospital Colorado, about the latest advancements in wound care and what patients can expect along the way. 

Why do so many indoor cats develop urinary disease? Meet Dr. Allison Kendall, Associate Professor of Internal Medicine at NC State and feline nephrology & urology specialist. In this episode of Purr Podcast, we talk pee, pain, and common causes for urinary probems in cats.

Adam creates a hypnosis session to help a client resist the temptation to have toilet breaks during the night when they didn't really need to go. This helps them to maintain their sleep for longer or to get back to sleep quickly even if they awake. To access a a subscriber-only version with no intro, outro, explanation, or ad breaks with just the hypnosis and nothing else click subscribe. To access all hypnosis-only versions and exclusive subscriber sessions and have invitations to live hypnosis sessions over Zoom, tap 'Subscribe' nearby or click the following link.⁠⁠⁠⁠⁠⁠⁠⁠⁠https://creators.spotify.com/pod/profile/adam-cox858/subscribe⁠⁠

A sensitive bladder affects one in three women of all ages. Many women who suffer from this condition just do not want to talk about it. Marilu Henner joins the To Your Good Health Radio Show to share why women should not feel self-conscious, isolated or alone.She explains that women should be open about it with their doctors, family and friends, and not let it hold them back.  

For the first time in history, a human bladder was transplanted. Dr. Nima Nassiri (UCLA) joins Dr. Ruchika Talwar to share how his team completed this landmark operation alongside a kidney transplant. He walks through the clinical scenario, key steps in donor and recipient selection, and how years of preclinical work informed the operative approach. --- SYNPOSIS The conversation explores the broader future of bladder transplant surgery, from ethical considerations to the potential for merging bladder transplantation with tolerance-induction protocols that could one day eliminate the need for lifelong immunosuppression. Dr. Nassiri reflects on the importance of patient-first decision-making, teamwork, and careful innovation as the field moves toward new possibilities in restorative urology and transplant medicine. --- TIMESTAMPS 00:00 - Introduction02:51 - The Path to Bladder Transplant Surgery05:00 - Scientific Challenges and Barriers06:45 - Patient Selection and Initial Outcomes12:28 - Quality of Life Considerations14:18 - Performing the First Bladder Transplant18:59 - Donor Matching21:28 - Ethical Considerations24:51 - Research Gaps and Future Prospects --- RESOURCES Clinical Trial: Vascularized Composite Bladder Allograft Transplantationhttps://www.clinicaltrials.gov/study/NCT05462561 Clinical Trial: Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplantshttps://clinicaltrials.gov/study/NCT05525507

Honoring Bladder Health Month! Originally Published September 2024. In this episode of Fempower Health, Dr. Tamra Lewis, a board-certified urogynecologist, discusses bladder health, UTI misdiagnoses, and how pelvic floor dysfunction, menopause, and the microbiome impact bladder issues in women. Learn how to advocate for better care and understand your symptoms.Bladder Health Episode SummaryIn this episode of Fempower Health, we sit down with Dr. Tamra Lewis, a board-certified urologist specializing in female pelvic medicine and reconstructive surgery (also known as urogynecology). Dr. Lewis shares her expertise on common bladder health issues affecting women, many of which are frequently misdiagnosed as urinary tract infections (UTIs). We explore the importance of accurate diagnoses, the potential causes of bladder issues, and how women can better advocate for themselves in healthcare settings. This episode is essential listening for women seeking clarity on their bladder health and for clinicians looking to improve patient outcomes.Discussion Points:Why are so many women misdiagnosing themselves with UTIs?What are the common symptoms of bladder problems in women?How can women better describe bladder issues to their healthcare provider?What are the underlying causes of frequent bladder issues in women?How can you tell the difference between a UTI and other bladder problems?Why is it important to have a pelvic exam for bladder issues?How does pelvic floor dysfunction contribute to bladder symptoms?What are the most effective treatments for overactive bladder?How can you prevent recurring urinary tract infections?What role does menopause play in bladder health?What is the impact of the microbiome on bladder health and UTIs?Why should women advocate for more thorough evaluations from their doctors?"It's easier to treat a small problem than to let a small problem become a bigger problem." - Dr. Tamra LewisRelated to this Bladder Health episode:Learn more about Dr. Tamra Lewis and follow her on LinkedIn and InstagramCheck out Fempower Health resources on Pelvic Health

Send us a textIn this episode, I'm taking you with me down into the Grand Canyon—21 miles, 13 hours, eight of us ages 44–53 (seven women, one very patient man), and every bit of trail talk you can imagine. What started as “Can we actually do this?” turned into the most honest, hilarious, and wide-open conversation about pelvic health, perimenopause, and how physical therapy for women has completely evolved since we were first told to “just do your Kegels.”Spoiler: the canyon will make you talk about everything.Is it sweat or is it pee?  Might be both.Bladder habits on switchbacks? Yep.Hormones while you're sweating through a sunset climb back to the rim? Absolutely.The stuff we wish someone told us 20 years ago? All of it.We get into:How women's health PT grew from basic kegels to running, lifting, sport, pregnancy → postpartum → peri/menopause careWhy it always comes back to the bladder (and why that's not a bad thing)The real story on preventative peeing + hovering on trail bathroomsWhat you should actually know about menopause hormone therapy (without the online panic spiral)Navigating peri/menopause with confidence, support, and a sense of humorIf you've ever wondered what happens when seven midlife women (& one very patient younger brother) take on the Grand Canyon… it's this. And it's so, so good.Time Stamps1:00 Introduction3:57 getting informed early5:20 taking a nature break on trail14:28 urine frequency and output19:39 unexpected leakage22:52 what we don't know about perimenopause28:40 weighted vests, walking, and yoga33:46 supplements38:00 exercise in pregnancy and postpartumCONNECT WITH CARRIEIG: https://www.instagram.com/carriepagliano/Website: https://carriepagliano.comThe Active Mom Podcast is A Real Moms' Guide to pregnancy, postpartum, perimenopause & beyond for active moms & the professionals who help them in their journey. This show has been a long time in the making! You can expect conversation with moms and professionals from all aspects of the industry. If you're like me, you don't have a lot of free time (heck, you're probably listening at 1.5x speed), so theses interviews will be quick hits to get your the pertinent information FAST! If you love what you hear, share the podcast with a friend and leave us a 5 ⭐⭐⭐⭐⭐ rating and review. It helps us become more visible in the search algorithm! (Helps us get seen by more moms that need to hear these stories!!!!)

Cough, laugh, sneeze… and leak? You're not alone — and it's not just "part of getting older." In this episode, Dr. Andrea McSwain unpacks the real reason women experience bladder leaks when they cough, laugh, or sneeze — and what it reveals about your pelvic floor, fascia, and hormone balance. You'll learn how declining estrogen and progesterone can change tissue strength, how pelvic muscles lose adaptability under chronic tension, and why holistic support (not just Kegels) is key to restoring control and confidence. Dr. McSwain also explores the surprising link between hormones and lung health — plus practical ways to reduce seasonal coughs, support tissue repair, and strengthen your core from the inside out. Whether you're in your 30s, postpartum, or perimenopausal, this episode will help you understand your body's signals, calm the frustration, and start healing naturally. #PelvicFloorHealth #BladderLeaks #HormoneBalance #WomensHealth #FunctionalMedicine #HolisticHealing #StressIncontinence

In this episode, Hannah is joined by her Coloplast colleague Polly Weston and Bladder and Bowel Nurse Consultant, Jane Young. Listen in for an open and honest conversation about bowel health where they tackle the so-called ‘Loo Taboo,'! They discuss breaking down the stigma around talking about bowel health and share expert insights to help make conversations about bowel health more empowering. Presented by Hannah Paterson Produced by Vibrant Sound Media This podcast is intended to support UK healthcare professionals with education. The information provided in this podcast is not a substitute for professional medical advice or treatment, and patients are encouraged to consult healthcare providers, including nurses, for any medical questions or concerns.

Urinary incontinence isn't “just part of getting older.” In this episode, Dr. Briana Walton, a urogynecologist at UM Capital Region Health, explains medical and surgical options to help, clears up myths, and shares why women don't have to live with bladder leaks in silence.  For more information about Dr. Walton 

The post 143 Bladder disorders – How you’ll see them on your exam appeared first on Physician Assistant Exam Review.

Urinary tract infections — or UTIs — aren't the most glamorous topic, but they're incredibly important, and we just don't talk about them enough. If you've ever had one, you'll know how miserable they can be: the burning, the stinging, those endless trips to the loo, the pain, and that bone-crushing fatigue. They can really knock you sideways.For many women, UTIs become more common — and more stubborn — during perimenopause and menopause.In this episode, I'm joined by the brilliant Helen Lake, a specialist urology nurse, to help us understand why UTIs happen, why they mustn't be ignored, and what you can do about them — from medical treatments to nutrition and supplements.Helen explains everything you need to know about identifying, understanding, and managing UTIs — and hopefully banishing them for good. We cover the key symptoms, prevention strategies like staying hydrated and double-voiding, why test results aren't always conclusive, and when antibiotics are needed. We also look at the role of beneficial bacteria, cranberry and D-mannose, vaginal moisturisers, topical oestrogen, and how to advocate for yourself with your GP.If you've found this episode helpful, please share it with a friend who might benefit too. And if you love The Happy Menopause podcast, I'd be so grateful if you could leave a five-star rating and a quick review on Apple Podcasts — or wherever you like to listen.And don't forget to subscribe, so you don't miss out on upcoming episodes. These small steps make a huge difference to the algorithm, and help more women find the show.After all, every woman deserves to have a happy menopause.Check out the full Show Notes for this episode on my website www.well-well-well.co.uk/podcast, where you'll find all the relevant links and references for each guest. Learn how to build your own menopause diet to manage your symptoms with my book The Happy Menopause: Smart Nutrition to Help You Flourish. And if you're tired of feeling tired and grappling with brain fog, check out my new book: The Happy Menopause Guide to Energy; Nutrition to Rejuvenate Your Brain & Body. It's available in all the usual places.

In this episode, Nichole Brooks, CRNP, breaks down common misconceptions about overactive bladder (OAB) and reminds listeners that bladder changes aren't simply something to “live with” as you age. She discusses what causes OAB, how it can impact daily life, and the effective treatment options available to help you regain control and confidence.

Bladder leaks are very common in women, especially after childbirth (even years after!). But you don't have to worry about needing adult diapers as you age because there is breakthrough treatment that can help. Emsella is a state of the art treatment for bladder incontinence. And if you've got questions about it, here are your answers! Want to try Emsella for just $49? Visit us at https://drjakewellness.com/emsella-socials

Send us a textCan one AI system learn from every organ — and teach us something new about all of them?In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before.From glomerulonephritis to hepatocellular carcinoma, AI is no longer confined to a single specialty — it's becoming the connective tissue between them.What's Inside:1️⃣ AI for Bladder Cancer Classification We begin with a multicenter study validating AI models for urothelial neoplasm classification using over 12,000 whole-slide images. Both CNNs and transformer models achieved high accuracy (AUC 0.983, F1 score 0.9). I discuss why the F1 score matters — and what it tells us about model balance between sensitivity and specificity.2️⃣ AI in Colorectal Cancer Care Next, we explore multimodal AI — integrating histopathology, radiology, genomics, and blood markers to modernize colorectal cancer workflows. AI now helps detect adenomas, infer microsatellite instability (MSI) from H&E slides, and predict treatment outcomes. I highlight the critical need for external validation, interpretability, and governance as AI enters clinical use.3️⃣ AI for Glomerular Nephritis Diagnosis A deep learning model trained on over 100,000 kidney biopsy images identified four nephritis types — FSGS, IgA, MN, and MCD — with over 85% accuracy. This technology could ease workloads and improve turnaround time in renal pathology. Still, I share why AI support may feel both empowering and unsettling for many pathologists.4️⃣ AI in Liver Disease (MASLD & HCC) AI is advancing noninvasive fibrosis staging and risk prediction in liver pathology. From large consortia like NIMBLE and LITMUS to predictive models for HCC therapy response, AI is moving us closer to precision hepatology. I also discuss the challenge of translating these tools from research to regulatory approval.5️⃣ Lightweight AI for Domain Generalization Finally, we look at one of pathology AI's biggest challenges: domain shift — when a model trained on one scanner or staining style performs poorly elsewhere. The new Histolite framework shows how lightweight, self-supervised models can generalize across data sources — trading some accuracy for reliability in real-world use.My TakeawayAcross every study, a single message stands out: AI isn't replacing pathologists — it's amplifying our vision. By connecting kidney, colon, liver, and bladder insights, AI is teaching us that medicine works best when it learns across boundaries.Episode HighlightsBladder cancer AI validation (06:41)Multimodal colorectal AI (12:38)Glomerular nephritis deep learning (19:29)AI in liver pathology (29:55)Domain shift & Histolite framework (38:17)Halloween wrap-up + SITC preview (46:18)Join me next time for updates from the SITC 2025 Conference, where I'll be live at Booth 415 with Hamamatsu and Biocare, discussing how AI and spatial biology are converging to drive clinical utility.#DigitalPathology #AIinHealthcare #ComputationalPathology #CancerDiagnostics #LiverPathology #RenalPathology #FutureOfMedicine #DigiPathDigestSupport the showGet the "Digital Pathology 101" FREE E-book and join us!

Send us a textUrologist Dr. Yaw Nyame joins Dr. Michael Koren to discuss bladder and prostate cancers. Dr. Nyame talks about his journey through college - including the choice between rock stardom and medical school - and how he got to the Fred Hutch Cancer Center in Seattle. Dr. Nyame explains symptoms, the history, and treatments for prostate and bladder cancer. He tells us "if you have blood in the urine, you definitely want to get to your primary care doctor." He also expands on gaps in cancer outcomes for Black men. Along the way, we weigh benefits and harms of PSA screening and talk honestly about sexual health after treatment.Show Note: Lynch syndrome is a genetic condition also known as hereditary nonpolyposis colorectal cancer (HNPCC). It represents an increased risk of several cancers, including colorectal, endometrial, gastric, ovarian, and pancreatic cancer. It is caused by an error in the DNA mismatch repair mechanism, which normally corrects for random insertions into the DNA code.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

Leaking after sneezing or exercising, rushing to the restroom and experiencing pelvic discomfort are health problems often tucked away on a to-do list of things to deal with later. These everyday disruptions though are signs that your pelvic floor needs some attention. Whether you've recently had a baby or you're approaching your menopause era, there are treatment options that can fit into your routine and help you feel better.  If you're looking for ways to support your bladder naturally or wondering how pelvic floor physical therapy could benefit you, you'll want to listen to the latest episode of The Healthiest You podcast. In Part Two of our pelvic floor podcast series, you'll hear from urogynecologist Nabila Noor, MD, and rehabilitation clinical specialist Karen Snowden, PT, DPT, both with Lehigh Valley Health Network, part of Jefferson Health.Which supplements may support your bladder health? What is pelvic organ prolapse? What treatment options are available for pelvic floor disorders? How can you strengthen your pelvic floor at home? What can you expect at your first pelvic floor physical therapy appointment? We answer these questions and more on The Healthiest You podcast this month.Chapters:     • 0:01 - Intro     • 0:04 - Toilet stools     • 3:52 - Bladder supplements     • 7:16 - Pelvic organ prolapse     • 9:11 - Treatment options     • 12:11 - Pelvic floor physical therapy     • 20:42 - Exercises at your appointment     • 26:20 - How to strengthen your pelvic floor at home     • 35:18 - Advice for your bladder and pelvic floor

Bladder leaks are no joke. If you don't stop them now, they often get worse. In this episode, Dr Jake shares information on a breakthrough treatment that is helping men and women with bladder leaks. Emsella is a state of the art treatment for bladder incontinence. And if you've got questions about it, here are your answers! Want to try Emsella for just $49? Visit us at https://drjakewellness.com/emsella-socials

In this episode, we explore:Why your body waits until the end of your shower to signal you need to peeHow this everyday moment reveals deeper truths about tension, distraction, and missed signalsWhat it means to actually feel safe enough to tune inWhy slowing down isn't indulgent—it's essentialHow this connects to mental health, nighttime overthinking, and suicide preventionThrive With Leo Coaching: If you want to reduce your psychological pain, regain your purpose and forge your own path, go to www.thrivewithleo.com to begin your journey.If you or anyone you know is considering suicide or self-harm, or is anxious, depressed, upset, or needs to talk, there are people who want to help:In the US: Crisis Text Line: Text CRISIS to 741741 for free, confidential crisis counseling. The National Suicide Prevention Lifeline: 1-800-273-8255 or 988The Trevor Project: 1-866-488-7386Outside the US:International Association for Suicide Prevention lists a number of suicide hotlines by country. Click here to find them.

This is one of the craziest client transformations to date! Katie broke her pelvis 13 years ago when she had her first baby. Ever since then she's been dealing with severe back pain, and bladder leaks bad enough to wear a pad all day. We started slow, but I had her lifting heavier with more intention, working on slowing down, and connecting back to her body and it shifted everything for her.If you feel like it's "too late" to fix pee leaks and back pain, you're wrong. It's never too late, you just need the right strategies in order to heal.If Katie's story hits home for you and you're ready to take the next step, click this link to get startedWork With Me:https://mailchi.mp/chloepufftraining/offers Connect with me on social media: Instagram: @chloepufftraining & @riseradiopod

Overactive bladder affects about 1 in 6 U.S. adults and disrupts sleep, focus, and confidence in daily life Low magnesium levels are strongly linked to higher rates of overactive bladder, with risk climbing steadily as depletion worsens Magnesium helps calm bladder muscles and reduce nerve overactivity, making sudden urges and leaks less frequent Inflammation triggered by magnesium deficiency further irritates bladder tissue and worsens symptoms Restoring magnesium through the right supplements and pairing it with bladder-friendly habits offers a natural, evidence-backed path to relief

In this episode of the "Southern Medicine Podcast", Tatiana Havryliuk, MD, and Randy Glick, BSB/PM, MCP detail a case of a 27-year-old male who presented with hematuria and abdominal discomfort. What began as a routine point-of-care ultrasound (POCUS) exam to assess urinary retention and possible renal colic led to the unexpected discovery of a bladder mass, prompting urgent imaging and follow-up. They discuss how POCUS can reveal critical pathology, guide timely intervention, reduce unnecessary radiation exposure, and enhance diagnostic accuracy in urgent and primary care settings. Dr. Tatiana Havryliuk is an emergency physician and founder of Hello Sono. With 15 years of experience using POCUS in diverse settings, from urban EDs to Everest Base Camp, she is dedicated to extending its benefits to more patients. With Hello Sono, she and her team support practices in building compliant, high-quality, and profitable POCUS programs through tailored education and implementation.

October 17, 2025 In this episode, Scott, Mark, and Ray Painter clarify the latest on the Medicare claims hold during the government shutdown, explaining that it applies only to services affected by expired COVID-era provisions like telehealth under traditional Medicare. They also address coding questions on billing for bladder stone removal during robotic prostatectomy—highlighting when to use 51050 vs. 51999—and revisit proper coding for Urocuff procedures following a UnitedHealthcare audit, emphasizing payer-specific strategies and the importance of reviewing operative details and coverage policies.Urology Advanced Coding and Reimbursement SeminarInformation and RegistrationPRS Coding and Reimbursement HubAccess the HubFree Kidney Stone Coding CalculatorDownload NowPRS Coding CoursesFor UrologistFor APPsFor Coders, Billers, and AdminsPRS Billing and Other Services - Book a Call with Mark Painter or Marianne DescioseClick Here to Get More Information and Request a Quote Join the Urology Pharma and Tech Pioneer GroupEmpowering urology practices to adopt new technology faster by providing clear reimbursement strategies—ensuring the practice gets paid and patients benefit sooner.         https://www.prsnetwork.com/joinuptpClick Here to Start Your Free Trial of AUACodingToday.com   The Thriving Urology Practice Facebook group.The Thriving Urology Practice Facebook Group link to join:https://www.facebook.com/groups/ThrivingPractice/ 

Your pelvic floor is ready and waiting for you to break up with these habits:Power-peeing – Going to the bathroom is not a race. Forcing urine out or relieving yourself as fast as you can causes more harm than good to your pelvic floor. Hovering – This seems like a natural solution to avoid germs in public restrooms. But hovering over the toilet tenses your muscles which makes your bladder work harder than it needs to.Peeing “just in case” – Went 15 minutes ago? Maybe going once more is a good idea … or is it? Whether you're heading out for an errand or a road trip, going again “just in case” is training your bladder to go more frequently.  If you're ready to take back control of your bladder, you'll want to listen to the latest episode of The Healthiest You podcast. In Part One of our pelvic floor podcast series, you'll hear from urogynecologist Nabila Noor, MD, and rehabilitation clinical specialist Karen Snowden, PT, DPT, with Lehigh Valley Health Network, part of Jefferson Health. How do you know if you have a pelvic floor disorder? What bathroom habits are harming your pelvic floor? How many times a day should you urinate? Can bladder training help? Which exercises can strengthen your pelvic floor? We answer these questions and more on The Healthiest You podcast this month.Chapters:     · 0:01 - Intro     · 0:17 - About your pelvic floor     · 3:31 - When your pelvic floor changes     · 6:49 - Signs you may have a pelvic floor disorder      · 15:54 - Treatment options     · 17:45 - Bladder leaks and overactive bladder      · 20:26 - How to address overactive bladder     · 23:56 - When to stop drinking before bed     · 29:06 - Bathroom no-nos     · 34:07 - Bladder training

Urinary incontinence affects millions of women, yet many continue to suffer in silence due to stigma or the misconception that it's just a normal part of aging. Bladder control issues can impact women of all ages, and they are highly treatable, and there are real solutions that can help. On this episode of the Healthier You Podcast, Dr. Ashlee Williams welcomes Dr. Nwamaka Fadahunsi, a board-certified urologist at Kaiser Permanente, to discuss the causes of urinary incontinence and the many tools available to treat it. Dr. Fadahunsi explains the differences between stress and urge incontinence, debunks common myths, and offers practical guidance on what women can do at home. She also outlines the full range of treatment options, including physical therapy, medications, and outpatient procedures, helping women regain control and confidence without relying on pads or assuming surgery is the only answer.  Learn more about Nwamaka Fadahunsi, MD 

Many people with Parkinson's disease experience urinary or bladder issues at some point in their journey. These symptoms can take different forms and may affect people differently based on gender. Recognizing the signs is the first step toward understanding how to manage them and when to seek care.   In this episode, Dr. Ankita Gupta, MD, MPH, FACOG, a urogynecologist at University of Louisville Hospital, talks about common bladder issues in Parkinson's, such as urinary frequency, urgency, and nocturia. She explains how these symptoms can affect quality of life and even contribute to social isolation, and she highlights treatment options that can help manage them.   Follow and rate us on your favorite podcast platform to be notified when there's a new episode! Let us know what other topics you would like us to cover by visiting parkinson.org/feedback.

No, it's not just a "weak pelvic floor."In fact, there's a surprising number of factors that contribute to bladder issues. Everything from the bra you wear to your menstrual cycle.Today we unpack what's causing those issues and how to mitigate symptoms so you can live pee-freeWork With Me:https://mailchi.mp/chloepufftraining/offers Connect with me on social media: Instagram: @chloepufftraining & @riseradiopod

Do you get the blues when the weather turns cool? In this episode, Dr. Motley tackles seasonal depression from a TCM perspective. In Traditional Chinese Medicine, the heart is connected to the kidneys and bladder, so if you feel that you're not your best self in the colder months, pay attention to signs of bladder issues.  Show Notes: ⬇️ For UTI testing: https://microgendx.com/ For kidney issues: Uva Ursi https://shorturl.at/QTKEK Your Seasonal Depression Recommendations: Sunshine Infrared Sauna Mineral Support (check out BEAM Minerals. You can get 20% off with code DRMOTLEY - https://shorturl.at/ySEiA) Multivitamins: Thorne Research https://www.thorne.com/products, and Xymogen EFT - https://www.thetappingsolution.com/ Neuroemotional Technique - https://netmindbody.com/ If you love this content and want more, check out Doctor Motley's YouTube Channel! ------  Follow Doctor Motley Instagram TikTok Facebook Website ------  *Do you have more questions for Doctor Motley about seasonal depression? Do you want to get deeper into his material? Take advantage of ALL Doctor Motley's clinical experience, with his membership where you can get the most out of your health and help the people you love. Check it out for free for 15 days: doctormotley.com/15 *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 *Charge your cells with pure antioxidant power! Liposomal supplementation has been proven deeply effective and LivOn Labs got there first. Get 10% off your liposomal supplements with code DROMTLEY at livonlabs.com Your Seasonal Depression Recommendations: Sunshine Infrared Sauna Mineral Support (check out BEAM Minerals. You can get 20% off with code DRMOTLEY - https://shorturl.at/W8MO5⁠) Multivitamins: Thorne Research https://www.thorne.com/products, and Xymogen https://shorturl.at/JIowR⁠ EFT - https://www.thetappingsolution.com/ Neuroemotional Technique - https://netmindbody.com/ If you love this content and want more, check out Doctor Motley's YouTube Channel! ------  Follow Doctor Motley Instagram: https://www.instagram.com/doctormotley https://www.tiktok.com/@doctormotley Facebook: https://www.facebook.com/doctormotley/ Website: https://doctormotley.com ------  *Do you have more questions for Doctor Motley about seasonal depression? Do you want to get deeper into his material? Take advantage of ALL Doctor Motley's clinical experience, with his membership where you can get the most out of your health and help the people you love. Check it out for free for 15 days: doctormotley.com/15 *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 *Charge your cells with pure antioxidant power! Liposomal supplementation has been proven deeply effective and LivOn Labs got there first. Get 10% off your liposomal supplements with code DROMTLEY at livonlabs.com

Back from speaking and a few live events, Sally shares about the importance of human connection & the longing we all have for community. Other Episode Highlights:Fall is here and so are the allergiesTrailfest & Mammoth 200 chatHiking for ice-creamSpeaking in MissouriImpactful stories and people Sally met in KY, TN, & MOKids and families Sally connected with Running with othersEarly morning coffee & gym routineConnect with Sally on LINKEDIN & on SUBSTACKGoing to be a Javelina this year? Let us know what you will be doing out there! Send us an email at contact@sallymcrae.comAll links, discounts, and ways to support the podcast are here.⁠⁠⁠⁠⁠⁠⁠Choose Strong Book ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sally McRae Strength App⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Choose Strong Podcast YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sally McRae YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Choose Strong Merch ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Bare Performance Nutrition⁠⁠⁠⁠⁠⁠⁠ Code: SALLY⁠⁠⁠⁠⁠⁠⁠Choose Strong Strava Group⁠⁠⁠⁠⁠⁠⁠Want to send us mail? Here is the address if you want to say hi!6771 Warner Ave. P.O. Box 2051Huntington Beach, CA 92647Episode Sponsors:Boncharge: boncharge.com w/ code SALLY to save 15%Janji: Go to ⁠⁠⁠⁠⁠janji.com ⁠⁠⁠⁠⁠and use code CHOOSESTRONG for 10% offPlan to Eat: plantoeat.com/sally for 25% off an annual subscription

In this episode of Mining the Comments, Coach Cristian addresses how hyper arousal affects the bladder, especially in those with insomnia. He shares personal experiences, explains the nervous system's role, and emphasizes the importance of acceptance in alleviating symptoms. Coach Cristian encourages viewers to respond gently and with patience to their body's signals. If you're new here and like what you've seen so far, you'll want to download our FREE 'Off-to-Dreamland' e-booklet. Simply head over to https://www.thesleepcoachschool.com and click the link at the tippy top. Happy reading!  If you're ready to leave insomnia for good, check out our coaching options. Head over to www.thesleepcoachschool.com and click on GET SLEEP in the menu. The Insomnia Immunity program is perfect if you like learning through video and want to join a group on your journey towards sleeping well. BedTyme is ideal if you like to learn via text and have a sleep coach in your pocket. The 1:1 Zoom based program is for you if you like to connect one on one with someone who has been where you are now.  Do you like learning by reading? If so, here are two books that offer breakthroughs! Tales of Courage by Daniel Erichsen https://www.amazon.com/Tales-Courage-Twenty-six-accounts-insomnia/dp/B09YDKJ3KX Set it & Forget it by Daniel Erichsen https://www.amazon.com/Set-Forget-ready-transform-sleep/dp/B08BW8KWDJ  Would you like to become a Sleep Hero by supporting the Natto movement on Patreon? If so, that's incredibly nice of you

Benign prostatic hyperplasia (BPH) impacts many men at some point as they age. Ramsay Kuo, MD, discusses why treatment is so important, and the growing number of options men have to improve quality of life and prevent irreversible bladder damage.You can also watch the video recording on our Vimeo channel here.For more health tips & news you can use from experts you trust, sign up for Sarasota Memorial's monthly digital newsletter, Healthe-Matters.

JCO PO authors Dr. Abhishek Tripathi and Dr. Salvador Jaime-Casas at City of Hope Comprehensive Cancer Center share insights into their article, “Comparative Genomic Characterization of Small Cell Carcinoma of the Bladder Compared With Urothelial Carcinoma and Small Cell Lung Carcinoma.”  Host Dr. Rafeh Naqash and Drs. Tripathi and Jaime-Casas discuss a novel understanding of the genomic alterations underlying SCBC, revealing actionable mutations that could serve as potential targets for improved clinical outcomes. TRANSCRIPT Dr. Rafeh Naqash: Hello and welcome to JCO Precision Oncology Conversations, where we bring you engaging conversations with authors of clinically relevant and highly significant JCO PO articles. I am your host, Dr. Dr. Rafeh Naqash, Podcast Editor for JCO Precision Oncology and Associate Professor at the OU Health Stephenson Cancer Center at the University of Oklahoma. Today, I am thrilled to be joined by Dr. Abhishek Tripathi, Associate Professor in the Department of Medical Oncology and Experimental Therapeutics Research at the City of Hope Comprehensive Cancer Center, as well as his mentee, Dr. Salvador Jaime-Casas, postdoctoral research fellow and first author of the JCO Precision Oncology article entitled "Comparative Genomic Characterization of Small Cell Carcinoma of the Bladder Compared with Urothelial Carcinoma and Small Cell Lung Carcinoma". At the time of this recording, our guest disclosures will be linked in the transcript. Abhishek and Salvador, welcome to our podcast and thank you for joining us today. This is a very interesting topic given that at least the landscape for neuroendocrine carcinomas, where small cell lung cancer is on one end of the spectrum, has been changing, at least on the lung cancer side, with recent approvals and some new ADCs. So, of course, understanding the genomic and transcriptomic similarities or differences between pulmonary small cell and extrapulmonary small cell is of huge interest. Could you tell us a little bit about small cell bladder cancer, current approaches to treatment of small cell bladder cancer, and then why you wanted to investigate that in this project as far as the genomic differences or similarities are concerned? Dr. Salvador Jaime-Casas: Well, first of all, thank you very much for having me. I am very excited to be here. And really what served as backbone for this research project was the notion that there is a currently evolving genomic landscape in the area of bladder cancer. We know this is a highly heterogeneous disease when it comes to molecular underpinnings and mutational profile. Specifically, we know that the most common histologic subtype is urothelial carcinoma. Small cell bladder cancer represents a histology that is found in less than 1% of all bladder cancer cases. However, it is one of the most aggressive histologies. It presents with a very poor prognosis to patients and very poor response to treatment, which is why we attempted to really elucidate what is the mutational profile behind this and provide a comparison contrast between small cell bladder cancer, small cell lung cancer, and conventional urothelial carcinoma. As your question mentioned, in terms of treatment, the conventional urothelial carcinoma and small cell bladder cancer are two distinct pathways when it comes to treatment algorithms. We know that in the current era there are newer and newer drugs being developed for conventional urothelial carcinoma. We have perioperative immunotherapy in the context of metastatic disease. We have antibody-drug conjugates such as enfortumab vedotin. But really, this amazing track record of drug development hasn't been mirrored in small cell bladder cancer. And here most of the therapy is usually extrapolated from studies from other small cell histologies like you mentioned earlier, small cell lung cancer has given some form of background in terms of what therapies are used here. Cytotoxic chemotherapy, for some patients with localized disease and small cell bladder cancer, concurrent chemotherapy and radiotherapy or perioperative cytotoxic chemotherapy have been the cornerstone of treatment for many years now. However, like I mentioned, the oncologic outcomes are very suboptimal when it comes to comparing it with other disease histologies, which is why we really wanted to describe the landscape here and provide this comparison across three different groups. For this particular study, we leveraged the Tempus dataset. So, include patients with urothelial carcinoma with small cell bladder cancer and small cell lung cancer. We included their demographic information, as well as the frequency of most common genomic alterations identified. And really, it was a very comparable Table 1. We see the demographic data across the three groups was very similar. One key thing that we identified was the female prevalence was a little bit lower in patients with small cell bladder cancer when compared to small cell lung cancer. But other than that, the age, race, ethnicity, was comparable across groups, and even the smoking history. Most of the patients in this cohort were former smokers, which we believe comes to explain that regardless of any mutational profile that we talked about in a few minutes, there are shared commonalities between these histologies and shared environmental exposures and risk factors that are going to be implicated in the disease biology for these three histologies. Dr. Rafeh Naqash: Thank you so much, Salvador, for that useful background. I would like to shift to Abhishek real quick. Abhishek, you are a practicing clinician, you have led several studies in the GU space, especially bladder. Based on what you see in the small cell lung cancer space, how drug development is shaping up, which aligns with what you are trying to evaluate in this paper as targets, how do you see some of that being implemented for small cell bladder cancer in the current era and age? Abhishek Tripathi: Thanks so much for the excellent question, Rafeh. As a GU investigator, small cell bladder cancer has always lagged behind in some regards regarding enrollment abilities for the novel clinical trials. And small cell lung cancer has paved the way and led the development of a lot of these drugs across the board. With the most recent sort of drugs targeting DLL3 already approved and several antibody-drug conjugates currently in development. That actually translates really well to how we should approach drug development in bladder cancer. What we saw in the study is that although there are overlaps and similarities between small cell lung cancer and small cell bladder cancer, there are also certain differences. So the long-term assumption that all therapies for small cell bladder cancer can be extrapolated to small cell bladder], may or may not be true, and I think it is high time that we specifically investigate these novel agents in tissue-specific small cell carcinomas. To that effect, we are excited to be participating in trials that are looking at some of the novel DLL3 targeted agents, specifically bispecific antibodies and T cell engagers so to speak, and antibody-drug conjugates that are now starting to open enrollment specifically in non-lung cancer cohorts to evaluate its efficacy. So overall, I think studies like this have the opportunity to identify more putative targets for organ-specific development of these novel agents. Dr. Rafeh Naqash: Absolutely, I could not agree more. I think tumor-agnostic therapies definitely have a place, but not all therapies work the same in different tumors with a similar histological or genomic background because there are definitely differences. So now going to the comparison that Salvador, you guys did in this project, could you help us understand what are some of the things you looked at, what were some of the commonalities and the differences, and what were some of the conceptual thoughts that come out from those results? Dr. Salvador Jaime-Casas: Of course. So, the first thing that we identified was which were the most frequent molecular alterations across these histologies. We actually provided a table showcasing how the most common mutations that we identified were TP53, TERT, RB1. However, like Dr. Tripathi mentioned, the distinction between these histologies is notable in the sense that some are more predominant in small cell-pertaining cancers such as bladder cancer and lung cancer. While some others are more common in bladder-pertaining malignancies like urothelial carcinoma and small cell bladder cancer. For instance, we saw that TP53 and RB1 were significantly more evident in small cell histologies, both small cell bladder cancer and small cell lung cancer, as opposed to conventional urothelial carcinoma, which really this mirrors what is known about these mutations and what has been published. These are markers associated with more aggressive disease with a worse prognosis and even to resistance to treatment. We also identified how TERT mutations were characteristically more prevalent in small cell bladder cancer as opposed to small cell lung cancer, as well as in urothelial carcinoma. TERT mutations were more commonly identified than in small cell lung cancer. And we give a long list of these mutations that we identified, but really what we wanted to underscore here was, A, the most common mutations across histologies; B, the most common co-occurring mutations where we saw that these are not mutually exclusive. A lot of patients had co-occurring TP53 and RB1 or RB1 and TERT or RB1 and ARID1A, really elucidating how heterogeneous this molecular landscape is across histologies. And the third one that we believe really brings down the clinical impact of this research was evidencing the idea of clinically actionable mutations. We also provided a table here showcasing how mutations like FGFR, DLL notch pathway, HER2, were evident in these histologies, and what is the current status of some clinical trials evaluating different drug designs for these mutations. Like Dr. Tripathi mentioned in the context of FGFR, approximately 6% of our cohort with small cell bladder cancer showcased mutations in FGFR3. However, up to 14% of them had mutations in any FGFR gene, which really underscores the notion that drugs like erdafitinib, which have been introduced in the market in recent years, could potentially showcase some response in the space of small cell bladder cancer. We actually provide the description of two trials, phase two, phase three trials, that are evaluating erdafitinib in the context of high-risk non-muscle invasive bladder cancer and even metastatic urothelial carcinoma. Like Dr. Tripathi mentioned as well, antibody-drug conjugates, another very interesting area of drug development targeting HER2, we included evidence on how disitamab vedotin and trastuzumab deruxtecan are currently being explored across different phase two and phase three clinical trials, both as part of basket trial designs for solid malignancies expressing HER2, but also for patients with urothelial carcinoma where there is evidence of HER2 expression. So, we believe that the landscape is shifting in the right direction in the sense that therapies are becoming much more personalized and targeted against these known molecular profiles. Dr. Rafeh Naqash: Thank you, Salvador, for summarizing some of those very interesting results and providing a very unique conceptual context to that. I would like to go to Abhishek this last portion. Of course, I am sure you guys will expand on this work and there are a lot of other interesting things that will likely come out from this work and hopefully you will publish that in JCO PO. But one of the very important things that I wanted to highlight from this podcast specifically was the science is obviously very interesting, but I feel the more important interesting aspect is giving trainees and fellows, residents, mentorship opportunities, mentoring them and giving them lead roles in projects like this, which is what Dr. Tripathi has successfully done for you in this project, Salvador. So, Abhishek, as somebody I have known for a couple of years now, more than a couple of years, as a very successful clinical translational investigator in the GU space in the early phase setting, Abhishek, really briefly, within a minute, could you tell us about your journey and what are some of the things that have worked for you as an early career investigator that you have learned from, and then your journey of mentorship, how has that been for you and what are some of the things that you take home from your mentorship role? Abhishek Tripathi: Absolutely. And as you mentioned, mentorship has been pivotal for all early career investigators for them to really succeed. So, my journey, as you know, I started off as an early career investigator at another institution, and I think I owe it to my mentors even at that time and even now who are helping me develop some of these newer translational and clinical trial ideas, creating opportunities where we could really showcase some of the interesting work that we are doing. That actually goes a long way in terms of creating independence as an established investigator. And I think the sooner we start off with mentorship prospects, I think the better it is. And paying it forward, I think I have been lucky to have mentees like Salvador who are just extremely talented, really committed, and goal-oriented. He really led the project right from the beginning in terms of initial analyses and looking up all the sort of correlative studies that we could do and the contextual data between small cell lung cancer and bladder cancer that we have delved into for the past several years. And it really showcases the ability of young mentees like Salvador to really excel given the right guidance and the support. As a mentor, it has been a really rewarding experience. It is really helpful to actually learn from some of these mentees as well as to approach the same problem from a different angle and different thought process and guide them through the study. So, it has been incredibly helpful and rewarding both being a mentee and a mentor over the past several years as I have transitioned. Dr. Rafeh Naqash: Thank you, Abhishek, for those very insightful comments on how both being a mentee and being a mentor helps shape you as an individual as well. And then you take a lot of pride in the success of your mentees. Now real quick, Salvador, could you tell us a little bit about yourself, you know, how you ended up at City of Hope under Dr. Tripathi's mentorship and what are some of the next important things that you are looking forward to doing? Dr. Salvador Jaime-Casas: So, a little bit about who I am. I did medical school in Mexico City. I was born and raised there, and towards the end of my medical training, I started to be engaged in research projects. And through one of my mentors in Mexico, I was actually introduced to the team here at City of Hope, including Dr. Tripathi. And through this, we got the opportunity to have some conversations about what I wanted to do, become a physician-researcher in the area of genitourinary oncology and hopefully my transition to residency in a few years. And that is how I came to be his mentee here at City of Hope. I think it has been a very rewarding experience, like Dr. Tripathi said, having such an incredible mentor and really being with him both in the academic setting and in the clinical setting, in patients with clinic, seeing this curiosity and all these clinical trials, all of this evidence that we have coming together to generate this insight. Dr. Rafeh Naqash: Thank you so much for both the scientific insights, as well as the journey of being a mentee for you, Salvador, and as a mentor for you, Abhishek. I really enjoyed talking to you guys about both aspects here today and hopefully we will see more of your work, Abhishek and Salvador, as far as understanding the transcriptomic heterogeneity in neuroendocrine tumors or neuroendocrine cancers of the bladder. Dr. Salvador Jaime-Casas: Thank you very much. Thank you for having us. Dr. Rafeh Naqash: Thank you for listening to JCO Precision Oncology Conversations. Do not forget to give us a rating or review and be sure to subscribe so you never miss an episode. You can find all ASCO shows at ASCO.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity or therapy should not be construed as an ASCO endorsement.   Dr. Abhishek Tripathi Disclosures Consulting or Advisory Role:  Company: Aadi biosciences, Seattle Genetics/Astellas, Exelixis, Bayer, Gilead Sciences, Pfizer, Deka biosciences Speakers' Bureau: Company: Sanofi

Cerebral palsy can affect bladder function in many different ways, often leading to challenges such as incontinence, urgency, or difficulties with emptying. In this episode, Madison Hughes and Dr. Sean Elliott discuss how cerebral palsy impacts the bladder, the common issues patients may face, and what families should know about treatment and management. 

Study Discovers Increased Cancers After MRNA Vaccines, Bret Weinstein- Covid & mRNA: Harms and Damages Exposed Bret Weinstein- Covid & mRNA: Harms and Damages Exposed (NEW!) REMINDER: CDC Didn't Track VAERS Safety Signals John Campbell- Increased cancers after mRNA vaccines   Study- Covid & mRNA: Harms and Damages Exposed (NEW!) | DarkHorse https://youtu.be/zkrbZmYuRoY?si=_0yO0y5ftLacoVJ1 Bret Weinstein 512K subscribers 25,699 views Sep 5, 2025 A new article on the harms and hazards of both SARS-CoV2 and the mRNA biologics said to counter the virus. Full Episode: https://youtube.com/live/wQWkKrM3Dt8 Mentioned in this segment: Zywiec et al 2025. COVID-19 Injections: Harms and Damages, a Non-Exhaustive Conclusion. Journal of American Physicians and Surgeons, 30(3): https://jpands.org/vol30no3/zywiec.pdf ***** Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com Heather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com Our book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned) Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org   REMINDER: CDC Didn't Track VAERS Safety Signals | DarkHorse https://youtu.be/u3UAyr6s7xc?si=VUoenskCyMdViArS Bret Weinstein 512K subscribers 16,906 views Sep 5, 2025 RFK Jr. fires the new director, after which other CDC officials resign, and eight former directors of the CDC pen a letter to the New York Times arguing that Kennedy is a hazard to our health. Bret Weinstein and Heather Heying discuss "The Plot Against Kennedy" in Episode 292 of The Evolutionary Lens. Full Episode: https://youtube.com/live/wQWkKrM3Dt8 Mentioned in this segment: NYT op-ed #2 from former CDC directors: We Ran the C.D.C.: Kennedy Is Endangering Every American's Health: https://www.nytimes.com/2025/09/01/op... Bret and Heather 132nd DarkHorse Podcast Livestream: 50 States not in a Roe https://youtube.com/live/usP2D_qGUZs CDC didn't monitor VAERS for COVID safety signals (June 2022): https://childrenshealthdefense.org/de...   Increased cancers after mRNA vaccines Watch this video at- https://youtu.be/3dnIGqUlluc?si=sDbAdXTgOsCiCLev Dr. John Campbell 3.25M subscribers 143,152 views Sep 5, 2025 COVID-19 vaccination, all-cause mortality, and hospitalization for cancer: 30-month cohort study in an Italian province https://pubmed.ncbi.nlm.nih.gov/40881... https://pmc.ncbi.nlm.nih.gov/articles... https://www.thefocalpoints.com/p/brea... The rate of first hospitalization for cancer of any site Unvaccinated group: 0.85% Vaccinated group (one or more doses): 1.15% N = 296,015 population Hospital admission with a cancer diagnosis, 3,124 (p less than 0.001). Vaccination with at least one dose Colon-rectal cancer HR: 1.34 Breast cancer HR: 1.54 Bladder cancer HR: 1.62 After three or more vaccine doses Breast cancer HR: 1.36 Bladder cancer HR: 1.43 All significant After one dose (180 days after) Rate of first hospital admissions for cancers All cancers: up 23% significant Colorectal: up 34% significant Lung: down = 10% Breast: up 54% significant Uterine: up = 75% Ovarian: up = 65% Prostate: up = 1% Bladder: up 62% significant Thyroid: up =58% Haematological: up = 33% After three dose (180 days after administration of third dose) All cancers: up = 9% Colorectal: up = 14% Lung: down = 5% Breast: up=36% significant Uterine: up = 20% Ovarian: up = 86% Prostate: down = 3% Bladder: up=43% significant Thyroid: down = 3% Haematological: up = 5% More about the study Population-wide cohort analysis Evaluating the risk of all-cause death and cancer hospitalization by SARS-CoV-2 immunization status. National Health System official data, entire population, Pescara province, Italy Followed from June 2021 (six months after the first vaccination) to December 2023. 296,015 residents aged ≥11 years Hospital admission with a cancer diagnosis, 3,124 16.6% were unvaccinated 83.3% received ≥1 dose 62.2% ≥3 doses. Compared with the unvaccinated, those receiving ≥1 dose showed a significantly lower likelihood of all-cause death Cancer hospitalization was significant only among the subjects with no previous SARS-CoV-2 infection Some cancer risks went down after 1 year (relative to 180 days) (But breast, ovarian and bladder went up at one year relative to 180 days after 1 vaccine dose) Given that it was not possible to quantify the potential impact of the healthy vaccinee bias and unmeasured confounders, these findings are inevitably preliminary.  

Send us a textHave you ever wondered why urinary issues seem to affect women differently than men? The answer lies in our unique anatomy and hormonal makeup — factors that make female urinary health both fascinating and complex.Dr. Holly Thacker takes listeners on a comprehensive journey through the most common urologic conditions affecting women during Urology Awareness Month. From the annoying but potentially dangerous urinary tract infections to the embarrassing reality of pelvic organ prolapse that affects up to one in eight women, this episode breaks down what's happening and why."Everyone needs a bladder that works," Dr. Thacker emphasizes as she explores how bladder health connects to overall wellness and quality of life. She tackles taboo topics with medical precision while offering practical advice for prevention and management. You'll learn why maintaining pelvic floor strength matters even if you've never been pregnant, how hormonal changes dramatically affect urologic health, and why sexual function is inextricably linked to bladder health.Subscribe to the Speaking of Women's Health Podcast wherever you listen to podcasts and visit speakingofwomenshealth.com for more resources on taking charge of your health.Support the show

In this episode of The Menopause and Cancer Podcast, we're joined by Dr Carys Sonnenberg — GP, menopause specialist, and women's health expert — for a practical, empowering workshop all about bladder health.We ask the questions many of us wonder but rarely say out loud:What's normal when it comes to bladder habits?How often is too often to wee?Urinary tract infections and treatmentsProlapse and what helpsDr Carys breaks it all down for us — from understanding how cancer treatment, menopause, and pelvic floor changes can affect bladder function, to simple and effective things you can do to feel more confident and in control.We also explore what can help, including:Pelvic floor exercisesLifestyle strategiesHormone-free treatmentsMedications that may be suitable for cancer survivorsEpisode Timestamps:00:00 Intro04:04 Understanding Bladder Health Issues07:24 Discussing Sensitive Health Symptoms12:27 Pelvic Floor and Bladder Health15:10 Urinary Health and Hygiene Tips19:11 Managing Acute & Recurrent UTIs21:34 Managing Recurrent Urine Infections24:54 Managing Bladder Urges & Incontinence33:20 Individualised Pelvic Floor Treatment34:59 Cancer, Intimacy, and Body Image44:46 Pelvic Floor Exercise Misconceptions50:01 Overcoming Pelvic Floor ChallengesBuy my book here: Navigating Menopause After Cancer: https://www.amazon.co.uk/Navigating-Menopause-After-Cancer-comprehensive/dp/1068499907You can find Dr Sonnenberg here https://rowenahealth.co.uk/These are resources Dr Sonnenberg mentions: https://thepogp.co.uk/resources/booklets/https://squeezyapp.com/ Connect with us:For more information and resources visit our website: www.menopauseandcancer.org Or follow us on Instagram @menopause_and_cancerJoin our Facebook group: www.facebook.com/groups/menopauseandcancerchathub

Contributor: Travis Barlock MD Educational Pearls: Meningitis retention syndrome is a relatively novel and rare clinical condition Aseptic meningitis + acute urinary retention One study reports an incidence of about 8% in patients with acute aseptic meningitis Clinical presentation Typical meningeal symptoms including fever, stiff neck, and headache Urinary retention occurs about one week after initial symptoms Potential pathophysiology Immune-mediated dysfunction of the central nervous system Detrusor muscle underactivity from inflammation of the spinal cord Management Supportive care Bladder decompression References Hiraga A, Kuwabara S. Meningitis-retention syndrome: Clinical features, frequency and prognosis. J Neurol Sci. 2018;390:261-264. doi:10.1016/j.jns.2018.05.008 Pellegrino F, Funiciello E, Pruccoli G, et al. Meningitis-retention syndrome: a review and update of an unrecognized clinical condition. Neurol Sci. 2023;44(6):1949-1957. doi:10.1007/s10072-023-06704-0 Summarized & Edited by Jorge Chalit, OMS4 Get your tickets to Tox Talks Event, Sept 11, 2025: https://emergencymedicalminute.org/events-2/ Donate: https://emergencymedicalminute.org/donate/  

Overactive bladder (urgency urinary incontinence) can feel overwhelming, emotionally and physically. Many women silently cycle through denial, frustration, and finally, acceptance. But living with constant urgency or leaking before reaching the bathroom doesn't have to be your “new normal.”In this episode, I break down first-line treatments for urgency incontinence, the practical, foundational steps every woman should try before turning to medications or procedures.You'll learn:How to keep a bladder diary to identify your personal triggers (from sparkling water to coffee).Why pelvic floor strengthening is key—and the difference between doing Kegels on your own vs. with support.How to practice urge suppression—the 5 quick contractions + calming breath technique that really works.The power of bladder retraining to teach your body to hold more comfortably over time.These tools don't just improve symptoms; they put you back in control, helping you feel less isolated and more hopeful.Additional resource,  BLADDER DIARY. Take this first step toward confidence and freedom from urgency.