Podcasts about bladder

In today's livestream, Tom discussed how Chris Shaw has weighed in about science, and also held a Q&A with questions previously submitted to us from our community.Topics included:-Soft tissue sarcomas-Bladder infections-Dental implants-Strophanthus-Injection in a child-How to talk to cardiologists-Is graphene real?-Electroculture in the garden-Primal diet-Can a mosquito transfer something into the blood and make you sick?-Herpes Simplex I and IISupport the showWebsites:https://drtomcowan.com/https://www.drcowansgarden.com/https://newbiologyclinic.com/https://newbiologycurriculum.com/Instagram: @TalkinTurkeywithTomFacebook: https://www.facebook.com/DrTomCowan/Bitchute: https://www.bitchute.com/channel/CivTSuEjw6Qp/YouTube: https://www.youtube.com/channel/UCzxdc2o0Q_XZIPwo07XCrNg

Please visit answersincme.com/FUA860 to participate, download slides and supporting materials, complete the post test, and get a certificate. In this activity, an expert in urology discusses overactive bladder in men with benign prostatic hyperplasia. Upon completion of this activity, participants should be better able to: Identify overactive bladder (OAB) in men who are being treated for benign prostatic hyperplasia (BPH); Review pharmacotherapy treatment expectations for treating OAB in men with BPH; and Formulate strategies to enhance treatment plans and support quality of life for men with OAB and BPH, including those with additional comorbidities.

In this week's episode, host Erin Gallardo, PT, DPT, NCS is joined by OT mentor Briana Elson, MS, OTR/L, BCPR, CBIS to dive into one of the most essential topics in spinal cord injury rehab: bowel and bladder care. We unpack why every rehab professional (not just nursing) plays a role, how unmanaged bowel and bladder can lead to serious health issues, and practical strategies to support independence, dignity, and community reintegration. Brianna shares equipment ideas, education tips, and real-world problem-solving for both bladder and bowel programs, plus how this all connects to intimacy, relationships, and quality of life after SCI.   Resources: Follow Mason Ellis on YouTube and share with your patients! Find a peer mentor through Christopher and Dana Reeve Foundation facingdisability.com https://www.sexualitysci.org/ https://otafterdark.com/ https://msktc.org/sci/factsheets/sexuality-sexual-functioning-after-sci https://craighospital.org/resources/sexual-function-for-women-after-spinal-cord-injury **As a note there are a couple of corrections in the episode we wanted to make clear: Bri may have misspoke… suprapubic catheters are placed below the belly button, not above. She may have said you can wear a bag with it, but you don't always have to. Disclaimer would be to defer to urology.

1 in 3 women deal with bladder leaks, with stress incontinence being the most common type of urinary incontinence. Most people & companies don't talk about it. This week's guest, Cntrl+ Founder Karen Brunet, created the most effective, comfortable, and reusable bladder support available for active women. Hear the top triggers for stress incontinence, how bladder leaks impact your confidence & physical activity levels, how Cntrl+ provides bladder support, how often you should wear it, and their focus on consumer safety & ease of use. Tune in to this episode to normalize the conversation around bladder leaks & bladder support.   Learn more: Cntrl+ Cntrl+ LinkedIn Karen Brunet   Today's Hot Flash and other stats from: Cleveland Clinic Mayo Clinic

Dr Nam Lee, LAc, PhD, QME, FABORM is the Founder of Lee Acupuncture Wellness Center Fellow of the American Board of Oriental Reproductive Medicine (ABORM)Dr. Nam Lee is a highly respected practitioner specializing in reproductive health, women's wellness, and fertility acupuncture. Dr. Lee is a Fellow of the American Board of Oriental Reproductive Medicine (ABORM), a Qualified Medical Evaluator certified by the California Medical Board, and holds a Ph.D. in Eastern Medicine from American Liberty University in Fullerton, CA. In 2015, she graduated from the Kalish Institute, receiving extensive clinical training in functional medicine with a focus on women's health and hormonal imbalance. She is also a certified Gokhale Method Primal Posture Teacher, emphasizing posture's role in overall health.In 2016, Dr. Lee apprenticed in Traditional Western Herbalism and is also a trained Traditional Chinese Medicine (TCM) herbalist, giving her a comprehensive understanding of herbal therapies across different traditions. She is deeply committed to a mind-body connection and a whole-person treatment approach, ensuring the best possible outcomes for her patients.https://www.leeacupuncture.com/https://www.facebook.com/leeacupuncturehttps://www.instagram.com/lee_acupuncture/https://www.youtube.com/@leeacup______________________________________________________________________________________Learn more about my pelvic health supplement line here https://rejeuve.com/Join my Buff Muff Method here https://get.buffmuff.com/methodThank you so much for listening! I use fitness and movement to help women prevent and overcome pelvic floor challenges like incontinence and organ prolapse. There is help for women in all life stages! Every Woman Needs A Vagina Coach! Please make sure to LEAVE A REVIEW and SUBSCRIBE to the show for the best fitness and wellness advice south of your belly button. *******************I recommend checking out my comprehensive pelvic health education and fitness programs on my Buff Muff AppYou can also join my next 28 Day Buff Muff Challenge https://www.vaginacoach.com/buffmuffIf you are feeling social you can connect with me… On Facebook https://www.facebook.com/VagCoachOn Instagram https://www.instagram.com/vaginacoach/On Twitter https://twitter.com/VaginaCoachOn The Web www.vaginacoach.comGet your Feel Amazing Vaginal Moisturizer Here

In this episode of The Birth Trauma Mama Podcast, Kayleigh sits down with Danielle, a therapist and mother of three, to share a story that challenges the narrow ways we often define birth and postpartum trauma.Danielle's trauma did not occur during labor or delivery, it unfolded months postpartum, following what was supposed to be a routine surgical procedure to remove a fibroid. Instead, a cascade of medical complications led to a medical emergency, multiple surgeries, bladder injury, and an unplanned hysterectomy that permanently ended her ability to carry another pregnancy.Already navigating life with three young children, including a baby under one, Danielle suddenly found herself recovering from a major abdominal surgery, managing a catheter for weeks, and confronting the profound grief of losing her fertility without warning or choice.As both a therapist and a patient, Danielle brings a deeply reflective lens to this conversation, naming the invisible grief that so often accompanies medical trauma, especially when it doesn't “fit” neatly into recognized categories of loss.Together, Kayleigh and Danielle explore:

Guests Dr. Andrea Necchi, Dr. Ashish Kamat and host Dr. Davide Soldato discuss JCO article "End Points for the Next-Generation Bladder-Sparing Perioperative Trials for Patients With Muscle-Invasive Bladder Cancer," focusing on the evolving treatment landscape of MIBC (muscle-invasive bladder cancer) and the need to properly design novel trials investigating non-operative management while including the incorporation of biomarkers and patient perspectives in clinical trials. TRANSCRIPT The disclosures for guests on this podcast can be found in the show notes. Dr. Davide Soldato: Hello and welcome to JCO After Hours, the podcast where we sit down with authors from some of the latest articles published in the Journal of Clinical Oncology. I am your host, Dr. Davide Soldato, medical oncologist at Ospedale San Martino in Genoa, Italy. Today we are joined by JCO authors Andrea Necchi, Associate Professor of Medical Oncology at University San Raffaele and Medical Oncology at Ospedale San Raffaele in Milan, Italy, and Ashish Kamat, Professor of Urologic Oncology and Cancer Research at University of Texas MD Anderson Cancer Center. Both Professor Necchi and Professor Kamat are internationally recognized experts in the field of genitourinary malignancy and particularly in bladder cancer. Today we will be discussing the article titled "Endpoints for the Next Generation Bladder-Sparing Perioperative Trials for Patients with Muscle-Invasive Bladder Cancer." So thank you for speaking with us, Professor Necchi and Professor Kamat. Dr. Andrea Necchi: Thank you, Davide, and thank you JCO for the opportunity. Dr. Ashish Kamat: Yeah, absolutely. It is a great honor and privilege to be discussing this very important article with you. So thank you for the invitation. Dr. Davide Soldato: The article that you just published in JCO reports the results of a consensus meeting that was held among experts in the field of genitourinary malignancy and particularly for bladder cancer. So the objective was really to define endpoints for a novel generation of trials among patients diagnosed with muscle-invasive bladder cancer. So my first question would be: what is the change in clinical practice and in clinical evidence that we have right now that prompted the start of such consensus in 2025? Dr. Andrea Necchi: So, we are living so many changes in the treatment paradigm of patients with muscle-invasive bladder cancer. In general, patients diagnosed with bladder cancer or urothelial cancer today, thanks to the advent of immunotherapy or immunotherapy combinations, and today thanks to the advent of novel antibody-drug conjugates like enfortumab vedotin in combination with immunotherapy that are actually changing the landscape of treatment of patients with metastatic disease and also are entering quite fast into the treatment paradigm of patients with organ-confined disease with a lot of clinical trials testing these combination therapies, neoadjuvantly or adjuvantly, before or after radical cystectomy. Having said that, by potentiating the efficacy of systemic therapy, an increasing number of patients that receive neoadjuvant therapy of any kind, at a certain point in time, result to have achieved a deep response to systemic therapy, evaluated radiologically with conventional imaging, CT scan or MRI, or with cystoscopy or with other urology-based techniques, urinary cytology, and so. And based on the fact that they achieve a complete response, so no residual viable disease after systemic therapy, they raise concern about the fact that they have to undergo surgery like radical cystectomy that is quite impactful for their quality of life and for the future of their lives after the surgery. So the point that the patients are raising, and the patients are raising this point, is primarily due to the efficacy of systemic therapy. And we have seen so many cases fortunately achieving a deep response. So the question about what to do with the patient that at a certain point, at the start with the commitment to radical cystectomy, but at a certain point in time change their mind towards something else if possible, depending on the fact that they have achieved a deep response, is something that is a question and is a need to which we have to provide data, information, and guidance in general to the patients. Dr. Davide Soldato: If we look at the population that the recommendations were formulated for, we are mainly speaking about patients who would be fit for cystectomy, and this is a very distinct population compared to those who are not fit for cystectomy, both from a medical oncology point of view but also from a urologic point of view in terms of surgery. So, can you explain a little bit to our listeners why you think that this distinction is critical and why you developed this recommendation especially for this population? Dr. Ashish Kamat: That is a very important distinction that you made. To build upon what Professor Necchi mentioned earlier, this question that we get from patients after neoadjuvant therapy or systemic therapy is not a new question. It has been something that they have been asking us for the last 20 or 30 years. "Do I really need to have my bladder taken out?" And patients who are especially not fit for surgery will sometimes say, "Do I need to have my bladder taken out? And if I cannot have my bladder taken out, am I going to just not have anything done?" Because the eligibility for radical cystectomy is also a moving target. Over the years with improvement in surgical technique, improvement in perioperative therapy, ERAS protocols, et cetera, it is really unusual for us to deny a patient the opportunity to have major surgery unless clearly they have very significant comorbid conditions. So I think this endeavor is more broadly encompassing of the patient population than what was evident in previous years. And I really want to give a shout out to Professor Necchi because what we did was, as part of the International Bladder Cancer Group and Professor Necchi is an integral part of the scientific advisory board, we broached this topic broadly during one of our discussions. And of course, Andrea always does this, he picks on a topic and then he says, "Okay, we need to discuss this really in detail," put together a multinational, multicenter collaborative group, but the driving force was our patients. Because our patients are constantly asking, "Do I need to lose my organ? Do I need to have radiation therapy?" which again, also, has a lot of side effects. So this was really to answer the question in today's day and age as to do we need to do local consolidation, and if so, in what way? It is not a new question, but we have newer therapies, newer technology, and better ways to answer this. So it is a much needed question that needs to be answered. And I think the distinction between non-surgical candidates and surgical candidates is a little bit blurred in today's day and age. Dr. Davide Soldato: What about the eligibility, for example, for cisplatin-based chemotherapy? Because I think that that is a very fundamental part of this type of strategy that we apply to patients with muscle-invasive bladder cancer. So we know that there are some caveats for proposing such treatment. And also this population was specifically defined inside this recommendation. Dr. Andrea Necchi: I think that the focus of our work is just to analyze what is happening after any type of systemic therapy the patient may get neoadjuvantly. So it is not actually a question of treatment eligibility or including cisplatin eligibility. This is an old question of today's practice and clinical trials. But regardless of what the patient received neoadjuvantly, the point that we have addressed in our consensus meeting was what to do next as a further step after systemic therapy or not. So basically we are- the consensus guidance includes all-comers, so patients to get any type of systemic therapy. So really non-selected based on specific features that determine a special eligibility to a special or a particular therapy. But an all-comer approach is always the winning approach for the translation to be in practice, an all-comer approach just focusing on what has happened after treatment and that we are assessing by the use of conventional imaging, MRI or CT, cystoscopy, urinary cytology, and trying to merge all together this information, all these features in a unique, shared, reliable definition of clinical complete response that could be used as a biomarker for the selection of newer therapies instead of pathological response that has been historically used, and maybe surrogate for the outcome, the long-term outcome and survival of these patients. Dr. Davide Soldato: A very specific point of the consensus was actually the definition of clinical complete response. As you were saying, this is actually a combination of several parameters including urinary cytology, the use of cross-sectional imaging, for example CT scan, but also the evaluation in cystoscopy of the bladder. Do you foresee any potential problems when applying this type of recommendation, not inside clinical trials, but in the context of routine clinical practice? Dr. Ashish Kamat: Absolutely. And that was the whole reason we had this consensus meeting. What happens nowadays in daily practice, and we see this every day at our center, we see patients referred to us. This definition or this sort of attempt to define clinical complete response is an ongoing issue. And urologists, medical oncologists, radiation oncologists are always looking to see, does my patient have a complete response? That definition and those paradigms have changed and evolved over the years. The FDA had a workshop many years ago looking at this very question. And it was to address the proposal that complete clinical response, which is a clinical definition, a clinical state, does this correlate with pathologic response? And with the technology and the systemic therapies we had then, the answer was 'no'. In fact, more patients got recurrent disease than did not get recurrent disease. And that is why, of course in the paper we mention the trials that looked at this question, the trials that evolved around this question. And I think the distinction between a clinical trial and daily practice is extremely important when we are looking at this definition per se. Because essentially what happens with this issue is that if the patient is not appropriately counseled, and if the physician does not do the appropriate clinical complete response assessment as Professor Necchi mentioned, right, cystoscopy, cytology, imaging, use of markers that are still in evolvement, we risk doing harm to the patient. So we caution in the paper too that this definition is not ready for prime time use. It is something that needs to be studied. It is a rigorous definition and currently we are recommending it for clinical trials. I am sure eventually it will trickle down into clinical practice, but that guidance was not the purpose of this consensus meeting. Dr. Davide Soldato: There are several parameters that are potentially evolving and could potentially enter inside of clinical practice. For example, you mentioned pelvic MRI and we have now very specific criteria, the VI-RADS criteria, we're able actually to diagnose and also to provide information. So along with these novel imaging techniques, we also know that there are novel biomarkers that could be explored, for example ctDNA and urinary DNA. So what I was wondering is, why were not these included inside the definition that you provide for clinical complete response? And do you think that, as we are designing these trials to potentially spare cystectomy for this patient, we should include these biomarkers very early so that we can actually provide better stratification for our patients and really propose this type of cystectomy-sparing strategy only to those where we are very confident that we have obtained a clinical complete response? Dr. Andrea Necchi: I would say you have just to wait. So a follow-up is ongoing and hard work is ongoing. At the time we met, at the time we established the meeting in mid-December last year, we had no information on the ctDNA data from major trials, with only a few exceptions. So we were just at the beginning of a story that was more than likely to change but still without numbers and without data from clinical trials. Now in just nine months or 10 months time, we have accumulated important data and newer data will be presented during just a few weeks and a few days regarding the ctDNA, circulating tumor DNA in particular, as a prognostic marker assessed baseline or assessed after neoadjuvant therapy. So the point is certainly well made and ctDNA is certainly well shaped to be incorporated in a future definition of clinical complete response. But you have to consider the fact that most of the data that we are accumulating related to ctDNA are about the post-cystectomy field or the metastatic field. So regarding neoadjuvant therapy, you know, we have neoadjuvant therapy in the context of bladder-sparing approach, basically we have no information. And the point that is emerging in our daily practice when using these biomarkers or in clinical trials, and the impression in general, is that it is a very strong biomarker associated with survival, but we absolutely do not know what is the performance of the test in the prediction of superficial bladder relapses, high-grade pTa relapse in the bladder that is left untouched in the patient. We are considering, and maybe it will be just a matter of further discussion, not just what is happening within the immediate endpoint of clinical CR, but also what is happening later with other survival endpoints. And for example, when looking at the type of events that we may see in this kind of bladder-sparing approaches, most of the events, also in the trials that have been published including the RETAIN study published in JCO, most of the events are related to superficial high-grade superficial non-muscle invasive relapses. So the ability to predict these types of events with ctDNA is completely unknown. Maybe, maybe other liquid biomarkers like urinary tumor DNA, utDNA, could be a bit better shaped in the prediction of this kind of events, you know. But we have still to build the story. So the question is good. The answer is yes, we will likely, more than likely incorporate liquid biomarkers in the definition, but we have to wait at least more data and more robust data in order to translate this information in routine practice, you know. Another consensus meeting is organized by IBCG and the same folks for November. This meeting will be primarily focused on the liquid biomarkers, the interpretation and use and approval and so of liquid biomarkers including bladder cancer. And we will likely be able to address all these, most of these open issues, so most of these points in the next meetings. Dr. Davide Soldato: In the consensus you say that probably clinical complete response is now ready to be included in early phase trials, so actually to test what is the efficacy of the regimens that is being evaluated inside of these trials. But you actually do very in-depth work of defining what are the most appropriate endpoints for later phase trials. So to be very specific, the phase three registrational trials that bring new regimens inside of this space. So I just wanted to hear a little bit about what was the definition for event-free survival, which you define as the most appropriate one for this type of trials. And as you were mentioning before, Professor Necchi, there is a very specific interest on the type of events that we observe, especially when we look at these superficial relapses inside of the bladder. So was this a very urgent matter of debate as we define which type of events should actually trigger event-free survival? And did you make a very thoughtful decision about why using this type of endpoint instead of others, for example metastasis-free survival? Dr. Ashish Kamat: Yeah, this was a matter of intense debate as you might imagine. And again, this is a moving target. So as Professor Necchi mentioned, we tend to partner with each other, our organizations, on having definitions of clinical complete response, biomarker, retreats, and then using that as a marker, and you might imagine this definition of what is appropriate event-free survival, what events matter to the patient, is something we have been talking about for two years. It was not just something that came up at the retreat. But at the retreat there was intense discussion. One of the things that we talked about was bladder-intact event-free survival because we are trying to spare the patient's bladder. And do we count bladder-intact event-free survival as something that is relevant? The patient advocates absolutely liked that, right? They wanted that. But then we also learned from some of the studies, for example from the RETAIN study, that the non-muscle invasive recurrences can actually lead to metastatic disease. It is not as benign when you have a patient with muscle-invasive bladder cancer that then develops a non-invasive tumor because maybe there is cancer growing underneath the surface that we don't detect when we look in the bladder. So a lot of those discussions were held, debated. It was a consensus. I have to say it was not 100% agreement on that particular definition, but it was broad consensus. And Andrea, do you want to clarify a little bit as to how we came about that consensus? Because I think this is a very important point we need to make. Dr. Andrea Necchi: We focused on a bit different definition of BI-EFS, Bladder-Intact Event-Free survival. Just stating EFS as an all-inclusive parameter including all type of high-grade relapse or progression or death that may happen to the patient. So that we were counting high-grade pTa, pT1, CIS relapses to the bladder and of course more deeper involvement in the muscle layer and so, and metastatic disease as a relapse. But the point is that as compared to the classical bladder-intact EFS definition of chemoradiation bladder-sparing approaches that is including muscle-invasive relapses only or death as events, we tried to be as inclusive as possible in order to be as much conservative as possible and to raise as higher the bar as possible for the success. And this is actually what the patients are asking us. So they are asking, "Okay, I can save my bladder, sparing radical cystectomy, but at which cost?" So in order to provide an answer, we have to be very, very cautious and be on the right shape, on the right position to say, "Okay, we have accomplished the most, the safest points, you know, by which you can proceed with the bladder-sparing." This is the first point. The other point is related to the MFS, metastasis-free survival that you have mentioned. For sure, it was recognized as a very important point for sure. But in the discussion was clear that our focus was in saving patients, curing the patient, and saving the bladder. Any single event, superficial event that may occur in the bladder-saving approaches of this kind may expose the patient to an extra risk of developing distant metastases, as it happened for example in the RETAIN study. So EFS defined as we have agreed and published, is actually a way of including or anticipating in a safest position the MFS. Because most or if not the entirety of the events of metastasis development in patients undergoing bladder-sparing after neoadjuvant systemic therapy were preceded by a superficial phase of disease relapse, you know. So I remember very, very few, or we can count just on the finger of one hand, the cases that have been reported in the literature developing de novo metastatic disease in the similar bladder-sparing approaches, in particular when using a maintenance immunotherapy strategy, you know, after they reach TURBT. So this is the reason why with all the limitation that Ashish has mentioned, with all the uncertainties that are still there, the nervousness that is still there, EFS, as defined in the protocol, as put in the paper, is to us at the moment is the safest way to use a primary endpoint in potentially registration trials of this kind with perioperative systemic therapy and response-adapted surgery. Dr. Ashish Kamat: And David, just to be absolutely clear for our listeners, right, so what was the event-free survival that we defined? Essentially it was a very inclusive definition. Event was defined as high-grade tumor persistence, recurrence, or progression during or after perioperative therapy, and receipt of any additional standard of care treatment including radical cystectomy, radiotherapy or even intravesical therapy. So this was done at the behest of our patient advocates because we really wanted to make a very robust definition that could be utilized appropriately as an adequate primary endpoint for both early and late phase bladder preservation trials. Dr. Davide Soldato: I think that it really highlights one of the points that I liked the most about this consensus is that it really incorporated the patient vision and a sort of shared decision making process when we are deciding how we want to design these trials that will explore this bladder-sparing surgery. And Professor Necchi mentioned something that I think will be also a very interesting question for trials that will be developed considering the activity of this combination that we are seeing right now, which is maintenance. Because right now our approach in the few cases where patients do not do any type of treatments after an induction with neoadjuvant treatments is basically represented by observation. So I was wondering if you think that the field will actually evolve to a sort of maintenance strategy even in patients that will achieve a complete clinical response? Dr. Andrea Necchi: We just mentioned briefly in the paper, this is a very important point that was touched during the discussion, and in particular was raised and discussed by FDA people participating in the meeting. And when looking at the data from the trials that were available and are still available thus far, we could provide a suggestion that maintenance immune therapy is the preferred approach in this kind of approach as it currently stands, as the data currently stand. Because the cleanest data towards the successful part of this journey is related to the studies that provided a kind of maintenance therapy, like the study with nivolumab or the RETAIN-2 study with maintenance immune therapy instead of RETAIN study that was just stopping treatment until surgery with MVAC chemotherapy. So in general the impression is that maintenance therapy may help in reducing the type of events, including the events that we incorporate in the EFS definition that we mentioned in the paper. The point that you mentioned is very important because on the other side we have a problem, a big problem of affordability and cost of the treatment. The de-escalation trials are an urgent need and represent a call for the studies. Unfortunately, as you mentioned, this is something that moves beyond the possibilities of this type of consensus because we don't have data and we have to accumulate data from clinical trials prior to saying, "Okay, certain patients could de-escalate therapy and stop therapy and some other not." So we are still at the very beginning. So we can do- we can discuss about this in the radical cystectomy paradigm but not in the bladder-sparing paradigm, you know. But this is for sure a point, a discussion point that will be taken, pretty well taken in one year or two year projection. Dr. Davide Soldato: I was wondering if in the consensus, considering that patient advocates and patient associations were also involved, did you decide to actually suggest the inclusion of patient-reported outcomes or the evaluation of shared decision-making in the development of this trial really as endpoints that should matter as much or as much as possible as event-free survival and clinical complete response? Dr. Ashish Kamat: Oh yeah, absolutely. We had patient advocates, we had the World Bladder Cancer Patient Coalition, Bladder Cancer Advocacy Network, patient representatives. And we always consider this. Shared decision-making is actually the impetus behind why these efforts have been launched, right? So it is the shared decision-making that is very, very important. It is the driving force behind what we do. And it is worth noting, for example, for the design of such studies, regulatory agencies consider response-based endpoints or overall survival as primary endpoints. But the patient advocates consider quality of life to be just as important, if not more important sometimes than overall survival numbers. Because patient advocates will say, "Well if I live longer but I'm miserable living longer, yes that works for regulatory agencies but doesn't work for us." So PROs clearly are very, very important. And, in fact, we just literally had a meeting in Houston, the IBCG meeting where PROs were a main point of what we discussed. So incorporating PROs in everything we do, not just this but everything we do, Dr. Necchi, myself, everybody involved in these fields realizes it is very, very important. So absolutely. Dr. Davide Soldato: I want to thank again Professor Necchi and Professor Kamat for joining us today. Dr. Andrea Necchi: Thank you. Dr. Ashish Kamat: It is our pleasure. Dr. Davide Soldato: Thanks again and we appreciate you sharing more on your JCO article titled "Endpoints for the Next Generation Bladder-Sparing Perioperative Trials for Patients with Muscle-Invasive Bladder Cancer." If you enjoy our show, please leave us a rating and review and be sure to come back for another episode. You can find all ASCO shows at asco.org/podcast. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.

Dr. Allison Kendall is back on the podcast, and she brings with her a fascinating deep dive into a completely new approach to treating feline idiopathic cystitis (FIC). Yes—you read that right. Radiation therapy, traditionally reserved for oncology patients, is now being explored as a potential tool for one of the most frustrating and painful conditions our feline friends face. Dr. Kendall walks us through the rationale, the early clinical findings, and why this modality might just shift our entire perspective on chronic lower urinary tract disease in cats. It's innovative, surprising, and exactly the kind of boundary-pushing veterinary medicine we love to highlight. From there, we pivot smoothly (or as smoothly as you can pivot when discussing irritated bladders) into another urinary challenge: difficult stones. Dr. Kendall unpacks the diagnostic traps, the surgical dilemmas, and the metabolic mysteries behind those stubborn uroliths that refuse to behave. Expect practical tips, thoughtful insights, and a few “aha” moments that will make you rethink your approach to these cases in practice. Another great conversation with one of our favorite guests: equal parts science, clinical pearls, and inspiration for anyone who has ever managed a blocked cat at 3 a.m.Thanks for tuning in to the Purr Podcast with Dr. Susan and Dr. Jolle!If you enjoyed today's episode, don't forget to subscribe, rate, and leave us a review—it really helps other cat lovers and vet nerds find the show. Follow us on social media for behind-the-scenes stories, cat trivia, and the occasional bad pun. And remember: every day is better with cats, curiosity, and maybe just a little purring in the background. Until next time—stay curious, stay kind, and give your cats an extra chin scratch from us. The Purr Podcast – where feline medicine meets feline fun.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Svetlana: Hello, could you please talk about incomplete bladder emptying in females specifically? What is causing it and what can be done to fix it? Someone said that squatting over the toilet without sitting on it to urinate could cause it. Is that true? This is the need of having to urinate again within 15mins of going the first time with small amounts of volume and difficulty "pushing" it out. No infection symptoms.                                                                                                                          Eric: Hi Dr. C, thanks for all your efforts! I use melatonin (extended release) regularly to help w/ sleep. A recent large international study published on the News Medical Life Sciences website, and presented at the American Heart Association's 2025 Scientific Sessions, stated that long-term users of melatonin had a higher risk of heart failure, hospitalization, and even death compared to those who didn't take it. The study looked at more than 130,000 adults with chronic insomnia. This sounds crazy to me. Any thoughts about this? Thanks.                                                                                  Audrey: Hi Dr. Cabral, Is doing a coffee enema while breastfeeding safe? I know detoxes are not safe, but I wasn't sure if a coffee enema is different because the main reason is to increase glutathione                                                                                           Angie: Hi Dr. Cabral, My last job I worked, there were a lot of wireless devices and 5G networks. I noticed how easily drained I would feel and I didn't even work a full 8 hours. I have been dealing with chronic pain and fatigue off and on for years now, and recently have been more cautious of how often I use technology. I am now seeing the trend of products like grounding mats and functional silver infused garments. Can you talk about the connection between adrenal fatigue and EMF exposure? And the new EMF products that may potentially reduce exposure or make it bearable to work in a high-tech environment. Thank you so much for all your help and support that you and your team provides!!       Savannah: Is there any supplement/herb/product to help someone with gastroparesis? what about acid reflux too? i'm wondering what can help with natural stimulation of the stomach nerve/muscle contractions in order to have a bowel movement. i was told that i have slow gut motility & little to no peristalsis. the only thing that works for me is senna but it takes extreme higher dosages. i completed the cbo protocol and finisher and everything was better but now im chronically constipated & have been diagnosed with gastroparesis. i use to go everyday during the protocol but now i feel that ive lost the gut/brain communication too.. as i no longer go by myself as im laxative & enema dependent. any advice? thank you in advance.         Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3593 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Takeaways:Slimmer's Paralysis is a recognized condition.Ethical boundaries are crucial in patient relationships.Medical professionals must maintain professionalism at all times.Humor can sometimes arise in serious discussions.Patient stories should always be handled with care.The importance of clear communication in medical settings.Understanding patient experiences is vital for effective care.Ethics in medicine is a complex and nuanced topic.Medical discussions can lead to unexpected topics.Maintaining a professional demeanor is essential.   Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Isaac is a medical-device innovator, entrepreneur, and the CEO & founder of Zida Therapeutics. He developed the Zida Control Sock, a wearable neuromodulation device intended to empower people living with urinary incontinence or overactive bladder to manage symptoms without relying solely on clinical  or pharmacalogical treatments.Isaac's passion for pelvic health comes from a deeply personal place. As he traced his family history, he learned his grandfather—who escaped Nazi Germany—struggled later in life with bladder control. That personal narrative sparked Isaac's mission: to create effective, noninvasive tools that can restore dignity and ease to the lives of those dealing with pelvic or bladder conditions.Under his leadership, Zida has secured FDA clearance for the Control Sock, and in early clinical use the device demonstrated ~80% “treatment success,” with meaningful reductions in urge incontinence and urinary frequency. Academically, Isaac holds a Master's in Technology Management, and professionally he's navigated the intersection of wearables, medical product development, and health tech start-ups. He's driven by the conviction that neuromodulation therapies should extend beyond clinic walls and into everyday life.Outside of his work with Zida, Isaac loves to spend time with his kids. https://livezida.com/https://www.facebook.com/p/Conquer-your-incontinence-ZIDA-control-sock-100064025981121/Thank you so much for listening! I use fitness and movement to help women prevent and overcome pelvic floor challenges like incontinence and organ prolapse. There is help for women in all life stages! Every Woman Needs A Vagina Coach! Please make sure to LEAVE A REVIEW and SUBSCRIBE to the show for the best fitness and wellness advice south of your belly button. *******************I recommend checking out my comprehensive pelvic health education and fitness programs on my Buff Muff AppYou can also join my next 28 Day Buff Muff Challenge https://www.vaginacoach.com/buffmuffIf you are feeling social you can connect with me… On Facebook https://www.facebook.com/VagCoachOn Instagram https://www.instagram.com/vaginacoach/On Twitter https://twitter.com/VaginaCoachOn The Web www.vaginacoach.comGet your Feel Amazing Vaginal Moisturizer Here

The boys are back! Barry Munro, John McAleavey, and Sasha Rabchevsky, three men with over 100 years of lived experience with spinal cord injury, have teamed up to share our knowledge on all things SCI related. Today's episode is dedicated to bladder management. We chronicle how each of us manages our situation (they're completely different), while also highlighting areas of need, concern, hope, and progress on the horizon, regarding this extremely important topic for the entire community.

Get my FREE ebook, ‘Rebalancing Your Hormones Naturally.' Actionable strategies for immediate results! 

Send us a textWelcome to Episode 2 of our Understanding Body Pain trilogy, where we explore how the lower body communicates through pain—and how Touch for Health and BioEnergetic Wellness can help you uncover the real root causes.In this episode, Dr. Michelle Greenwell is joined by Denise Cambiotti, HCD CIH BioEW, of www.muscletuners.ca and Kate Montgomery, HHP, ND as they guide you through the interconnected world of muscles, meridians, reflexes, tendons, ligaments, fascia, and posture. Pain rarely appears where it begins—plantar fasciitis, knee pain, hip tension, or ankle instability often stem from hidden imbalances that biofeedback can reveal.We begin by standing together and noticing the 9 points on the feet—a simple but powerful checkpoint for body alignment. Throughout the episode, you'll learn how the lower body compensates, how misalignment builds over time, and how muscle monitoring helps identify the true priority for healing.Topics We Explore:✨ How the lower-body meridians (including Bladder & Kidney) relate to muscle function✨ The role of gait patterns and how walking reveals hidden imbalances✨ How calf and foot tension are linked (including the deeper origin of plantar fasciitis)✨ Hip misalignment and its downstream effects on knees, ankles, and feet✨ Muscle monitoring for uncovering priority issues✨ Stories from clinical practice and athletic performance✨ Simple tools you can use today to restore balance

Joylux is is a proven at-home red light device for enhancing and revitalizing your vagina. If you're suffering from bladder leaks, vaginal dryness, or painful sex, this is an episode you don't want to miss. If you're read ing this on Black Friday, today is the ONE DAY of the year where they offer their highest discount: 25% off! Shop now!New episodes of Welcome to Wellness released every Friday!

Why do so many indoor cats develop urinary disease? Meet Dr. Allison Kendall, Associate Professor of Internal Medicine at NC State and feline nephrology & urology specialist. In this episode of Purr Podcast, we talk pee, pain, FIC, minimally invasive procedures, and why the bladder is just the beginning when it comes to cat urinary disease.Thanks for tuning in to the Purr Podcast with Dr. Susan and Dr. Jolle!If you enjoyed today's episode, don't forget to subscribe, rate, and leave us a review—it really helps other cat lovers and vet nerds find the show. Follow us on social media for behind-the-scenes stories, cat trivia, and the occasional bad pun. And remember: every day is better with cats, curiosity, and maybe just a little purring in the background. Until next time—stay curious, stay kind, and give your cats an extra chin scratch from us. The Purr Podcast – where feline medicine meets feline fun.

Why do we ignore the bladder… until the exact moment it refuses to be ignored? In this pre-Thanksgiving episode, Dr. Stephanie Hack is joined by expert urogynecologist Dr. Charelle Carter-Brooks to break down the bladder symptoms that sneak up on women during perimenopause, postpartum, and the busy midlife years. They talk urgency, leaks, “mom jumps,” nighttime peeing, and the pelvic floor habits we were never taught — including the surprising thing most women do on the toilet that actually makes their symptoms worse. If you've ever wondered, “Is this normal?” this episode is your clarity.

Wound care is an important part of recovery for patients with neurogenic bladder undergoing complex lower urinary tract surgery. In this episode, Madison Hughes talks with Dr. Kyle Rove and Dr. Kelly Harris, pediatric urologists at Children's Hospital Colorado, about the latest advancements in wound care and what patients can expect along the way. 

Why do so many indoor cats develop urinary disease? Meet Dr. Allison Kendall, Associate Professor of Internal Medicine at NC State and feline nephrology & urology specialist. In this episode of Purr Podcast, we talk pee, pain, and common causes for urinary probems in cats.

Adam creates a hypnosis session to help a client resist the temptation to have toilet breaks during the night when they didn't really need to go. This helps them to maintain their sleep for longer or to get back to sleep quickly even if they awake. To access a a subscriber-only version with no intro, outro, explanation, or ad breaks with just the hypnosis and nothing else click subscribe. To access all hypnosis-only versions and exclusive subscriber sessions and have invitations to live hypnosis sessions over Zoom, tap 'Subscribe' nearby or click the following link.⁠⁠⁠⁠⁠⁠⁠⁠⁠https://creators.spotify.com/pod/profile/adam-cox858/subscribe⁠⁠

A sensitive bladder affects one in three women of all ages. Many women who suffer from this condition just do not want to talk about it. Marilu Henner joins the To Your Good Health Radio Show to share why women should not feel self-conscious, isolated or alone.She explains that women should be open about it with their doctors, family and friends, and not let it hold them back.  

For the first time in history, a human bladder was transplanted. Dr. Nima Nassiri (UCLA) joins Dr. Ruchika Talwar to share how his team completed this landmark operation alongside a kidney transplant. He walks through the clinical scenario, key steps in donor and recipient selection, and how years of preclinical work informed the operative approach. --- SYNPOSIS The conversation explores the broader future of bladder transplant surgery, from ethical considerations to the potential for merging bladder transplantation with tolerance-induction protocols that could one day eliminate the need for lifelong immunosuppression. Dr. Nassiri reflects on the importance of patient-first decision-making, teamwork, and careful innovation as the field moves toward new possibilities in restorative urology and transplant medicine. --- TIMESTAMPS 00:00 - Introduction02:51 - The Path to Bladder Transplant Surgery05:00 - Scientific Challenges and Barriers06:45 - Patient Selection and Initial Outcomes12:28 - Quality of Life Considerations14:18 - Performing the First Bladder Transplant18:59 - Donor Matching21:28 - Ethical Considerations24:51 - Research Gaps and Future Prospects --- RESOURCES Clinical Trial: Vascularized Composite Bladder Allograft Transplantationhttps://www.clinicaltrials.gov/study/NCT05462561 Clinical Trial: Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplantshttps://clinicaltrials.gov/study/NCT05525507

Honoring Bladder Health Month! Originally Published September 2024. In this episode of Fempower Health, Dr. Tamra Lewis, a board-certified urogynecologist, discusses bladder health, UTI misdiagnoses, and how pelvic floor dysfunction, menopause, and the microbiome impact bladder issues in women. Learn how to advocate for better care and understand your symptoms.Bladder Health Episode SummaryIn this episode of Fempower Health, we sit down with Dr. Tamra Lewis, a board-certified urologist specializing in female pelvic medicine and reconstructive surgery (also known as urogynecology). Dr. Lewis shares her expertise on common bladder health issues affecting women, many of which are frequently misdiagnosed as urinary tract infections (UTIs). We explore the importance of accurate diagnoses, the potential causes of bladder issues, and how women can better advocate for themselves in healthcare settings. This episode is essential listening for women seeking clarity on their bladder health and for clinicians looking to improve patient outcomes.Discussion Points:Why are so many women misdiagnosing themselves with UTIs?What are the common symptoms of bladder problems in women?How can women better describe bladder issues to their healthcare provider?What are the underlying causes of frequent bladder issues in women?How can you tell the difference between a UTI and other bladder problems?Why is it important to have a pelvic exam for bladder issues?How does pelvic floor dysfunction contribute to bladder symptoms?What are the most effective treatments for overactive bladder?How can you prevent recurring urinary tract infections?What role does menopause play in bladder health?What is the impact of the microbiome on bladder health and UTIs?Why should women advocate for more thorough evaluations from their doctors?"It's easier to treat a small problem than to let a small problem become a bigger problem." - Dr. Tamra LewisRelated to this Bladder Health episode:Learn more about Dr. Tamra Lewis and follow her on LinkedIn and InstagramCheck out Fempower Health resources on Pelvic Health

Send us a textIn this episode, I'm taking you with me down into the Grand Canyon—21 miles, 13 hours, eight of us ages 44–53 (seven women, one very patient man), and every bit of trail talk you can imagine. What started as “Can we actually do this?” turned into the most honest, hilarious, and wide-open conversation about pelvic health, perimenopause, and how physical therapy for women has completely evolved since we were first told to “just do your Kegels.”Spoiler: the canyon will make you talk about everything.Is it sweat or is it pee?  Might be both.Bladder habits on switchbacks? Yep.Hormones while you're sweating through a sunset climb back to the rim? Absolutely.The stuff we wish someone told us 20 years ago? All of it.We get into:How women's health PT grew from basic kegels to running, lifting, sport, pregnancy → postpartum → peri/menopause careWhy it always comes back to the bladder (and why that's not a bad thing)The real story on preventative peeing + hovering on trail bathroomsWhat you should actually know about menopause hormone therapy (without the online panic spiral)Navigating peri/menopause with confidence, support, and a sense of humorIf you've ever wondered what happens when seven midlife women (& one very patient younger brother) take on the Grand Canyon… it's this. And it's so, so good.Time Stamps1:00 Introduction3:57 getting informed early5:20 taking a nature break on trail14:28 urine frequency and output19:39 unexpected leakage22:52 what we don't know about perimenopause28:40 weighted vests, walking, and yoga33:46 supplements38:00 exercise in pregnancy and postpartumCONNECT WITH CARRIEIG: https://www.instagram.com/carriepagliano/Website: https://carriepagliano.comThe Active Mom Podcast is A Real Moms' Guide to pregnancy, postpartum, perimenopause & beyond for active moms & the professionals who help them in their journey. This show has been a long time in the making! You can expect conversation with moms and professionals from all aspects of the industry. If you're like me, you don't have a lot of free time (heck, you're probably listening at 1.5x speed), so theses interviews will be quick hits to get your the pertinent information FAST! If you love what you hear, share the podcast with a friend and leave us a 5 ⭐⭐⭐⭐⭐ rating and review. It helps us become more visible in the search algorithm! (Helps us get seen by more moms that need to hear these stories!!!!)

Cough, laugh, sneeze… and leak? You're not alone — and it's not just "part of getting older." In this episode, Dr. Andrea McSwain unpacks the real reason women experience bladder leaks when they cough, laugh, or sneeze — and what it reveals about your pelvic floor, fascia, and hormone balance. You'll learn how declining estrogen and progesterone can change tissue strength, how pelvic muscles lose adaptability under chronic tension, and why holistic support (not just Kegels) is key to restoring control and confidence. Dr. McSwain also explores the surprising link between hormones and lung health — plus practical ways to reduce seasonal coughs, support tissue repair, and strengthen your core from the inside out. Whether you're in your 30s, postpartum, or perimenopausal, this episode will help you understand your body's signals, calm the frustration, and start healing naturally. #PelvicFloorHealth #BladderLeaks #HormoneBalance #WomensHealth #FunctionalMedicine #HolisticHealing #StressIncontinence

Urinary incontinence isn't “just part of getting older.” In this episode, Dr. Briana Walton, a urogynecologist at UM Capital Region Health, explains medical and surgical options to help, clears up myths, and shares why women don't have to live with bladder leaks in silence.  For more information about Dr. Walton 

The post 143 Bladder disorders – How you’ll see them on your exam appeared first on Physician Assistant Exam Review.

Urinary tract infections — or UTIs — aren't the most glamorous topic, but they're incredibly important, and we just don't talk about them enough. If you've ever had one, you'll know how miserable they can be: the burning, the stinging, those endless trips to the loo, the pain, and that bone-crushing fatigue. They can really knock you sideways.For many women, UTIs become more common — and more stubborn — during perimenopause and menopause.In this episode, I'm joined by the brilliant Helen Lake, a specialist urology nurse, to help us understand why UTIs happen, why they mustn't be ignored, and what you can do about them — from medical treatments to nutrition and supplements.Helen explains everything you need to know about identifying, understanding, and managing UTIs — and hopefully banishing them for good. We cover the key symptoms, prevention strategies like staying hydrated and double-voiding, why test results aren't always conclusive, and when antibiotics are needed. We also look at the role of beneficial bacteria, cranberry and D-mannose, vaginal moisturisers, topical oestrogen, and how to advocate for yourself with your GP.If you've found this episode helpful, please share it with a friend who might benefit too. And if you love The Happy Menopause podcast, I'd be so grateful if you could leave a five-star rating and a quick review on Apple Podcasts — or wherever you like to listen.And don't forget to subscribe, so you don't miss out on upcoming episodes. These small steps make a huge difference to the algorithm, and help more women find the show.After all, every woman deserves to have a happy menopause.Check out the full Show Notes for this episode on my website www.well-well-well.co.uk/podcast, where you'll find all the relevant links and references for each guest. Learn how to build your own menopause diet to manage your symptoms with my book The Happy Menopause: Smart Nutrition to Help You Flourish. And if you're tired of feeling tired and grappling with brain fog, check out my new book: The Happy Menopause Guide to Energy; Nutrition to Rejuvenate Your Brain & Body. It's available in all the usual places.

In this episode, Nichole Brooks, CRNP, breaks down common misconceptions about overactive bladder (OAB) and reminds listeners that bladder changes aren't simply something to “live with” as you age. She discusses what causes OAB, how it can impact daily life, and the effective treatment options available to help you regain control and confidence.

Bladder leaks are very common in women, especially after childbirth (even years after!). But you don't have to worry about needing adult diapers as you age because there is breakthrough treatment that can help. Emsella is a state of the art treatment for bladder incontinence. And if you've got questions about it, here are your answers! Want to try Emsella for just $49? Visit us at https://drjakewellness.com/emsella-socials

Send us a textCan one AI system learn from every organ — and teach us something new about all of them?In this edition of DigiPath Digest #31, I explore how artificial intelligence is transforming pathology across multiple organ systems, revealing connections that help us diagnose faster, more consistently, and more accurately than ever before.From glomerulonephritis to hepatocellular carcinoma, AI is no longer confined to a single specialty — it's becoming the connective tissue between them.What's Inside:1️⃣ AI for Bladder Cancer Classification We begin with a multicenter study validating AI models for urothelial neoplasm classification using over 12,000 whole-slide images. Both CNNs and transformer models achieved high accuracy (AUC 0.983, F1 score 0.9). I discuss why the F1 score matters — and what it tells us about model balance between sensitivity and specificity.2️⃣ AI in Colorectal Cancer Care Next, we explore multimodal AI — integrating histopathology, radiology, genomics, and blood markers to modernize colorectal cancer workflows. AI now helps detect adenomas, infer microsatellite instability (MSI) from H&E slides, and predict treatment outcomes. I highlight the critical need for external validation, interpretability, and governance as AI enters clinical use.3️⃣ AI for Glomerular Nephritis Diagnosis A deep learning model trained on over 100,000 kidney biopsy images identified four nephritis types — FSGS, IgA, MN, and MCD — with over 85% accuracy. This technology could ease workloads and improve turnaround time in renal pathology. Still, I share why AI support may feel both empowering and unsettling for many pathologists.4️⃣ AI in Liver Disease (MASLD & HCC) AI is advancing noninvasive fibrosis staging and risk prediction in liver pathology. From large consortia like NIMBLE and LITMUS to predictive models for HCC therapy response, AI is moving us closer to precision hepatology. I also discuss the challenge of translating these tools from research to regulatory approval.5️⃣ Lightweight AI for Domain Generalization Finally, we look at one of pathology AI's biggest challenges: domain shift — when a model trained on one scanner or staining style performs poorly elsewhere. The new Histolite framework shows how lightweight, self-supervised models can generalize across data sources — trading some accuracy for reliability in real-world use.My TakeawayAcross every study, a single message stands out: AI isn't replacing pathologists — it's amplifying our vision. By connecting kidney, colon, liver, and bladder insights, AI is teaching us that medicine works best when it learns across boundaries.Episode HighlightsBladder cancer AI validation (06:41)Multimodal colorectal AI (12:38)Glomerular nephritis deep learning (19:29)AI in liver pathology (29:55)Domain shift & Histolite framework (38:17)Halloween wrap-up + SITC preview (46:18)Join me next time for updates from the SITC 2025 Conference, where I'll be live at Booth 415 with Hamamatsu and Biocare, discussing how AI and spatial biology are converging to drive clinical utility.#DigitalPathology #AIinHealthcare #ComputationalPathology #CancerDiagnostics #LiverPathology #RenalPathology #FutureOfMedicine #DigiPathDigestSupport the showGet the "Digital Pathology 101" FREE E-book and join us!

Send us a textUrologist Dr. Yaw Nyame joins Dr. Michael Koren to discuss bladder and prostate cancers. Dr. Nyame talks about his journey through college - including the choice between rock stardom and medical school - and how he got to the Fred Hutch Cancer Center in Seattle. Dr. Nyame explains symptoms, the history, and treatments for prostate and bladder cancer. He tells us "if you have blood in the urine, you definitely want to get to your primary care doctor." He also expands on gaps in cancer outcomes for Black men. Along the way, we weigh benefits and harms of PSA screening and talk honestly about sexual health after treatment.Show Note: Lynch syndrome is a genetic condition also known as hereditary nonpolyposis colorectal cancer (HNPCC). It represents an increased risk of several cancers, including colorectal, endometrial, gastric, ovarian, and pancreatic cancer. It is caused by an error in the DNA mismatch repair mechanism, which normally corrects for random insertions into the DNA code.Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!

Leaking after sneezing or exercising, rushing to the restroom and experiencing pelvic discomfort are health problems often tucked away on a to-do list of things to deal with later. These everyday disruptions though are signs that your pelvic floor needs some attention. Whether you've recently had a baby or you're approaching your menopause era, there are treatment options that can fit into your routine and help you feel better.  If you're looking for ways to support your bladder naturally or wondering how pelvic floor physical therapy could benefit you, you'll want to listen to the latest episode of The Healthiest You podcast. In Part Two of our pelvic floor podcast series, you'll hear from urogynecologist Nabila Noor, MD, and rehabilitation clinical specialist Karen Snowden, PT, DPT, both with Lehigh Valley Health Network, part of Jefferson Health.Which supplements may support your bladder health? What is pelvic organ prolapse? What treatment options are available for pelvic floor disorders? How can you strengthen your pelvic floor at home? What can you expect at your first pelvic floor physical therapy appointment? We answer these questions and more on The Healthiest You podcast this month.Chapters:     • 0:01 - Intro     • 0:04 - Toilet stools     • 3:52 - Bladder supplements     • 7:16 - Pelvic organ prolapse     • 9:11 - Treatment options     • 12:11 - Pelvic floor physical therapy     • 20:42 - Exercises at your appointment     • 26:20 - How to strengthen your pelvic floor at home     • 35:18 - Advice for your bladder and pelvic floor

Bladder leaks are no joke. If you don't stop them now, they often get worse. In this episode, Dr Jake shares information on a breakthrough treatment that is helping men and women with bladder leaks. Emsella is a state of the art treatment for bladder incontinence. And if you've got questions about it, here are your answers! Want to try Emsella for just $49? Visit us at https://drjakewellness.com/emsella-socials

In this episode, we explore:Why your body waits until the end of your shower to signal you need to peeHow this everyday moment reveals deeper truths about tension, distraction, and missed signalsWhat it means to actually feel safe enough to tune inWhy slowing down isn't indulgent—it's essentialHow this connects to mental health, nighttime overthinking, and suicide preventionThrive With Leo Coaching: If you want to reduce your psychological pain, regain your purpose and forge your own path, go to www.thrivewithleo.com to begin your journey.If you or anyone you know is considering suicide or self-harm, or is anxious, depressed, upset, or needs to talk, there are people who want to help:In the US: Crisis Text Line: Text CRISIS to 741741 for free, confidential crisis counseling. The National Suicide Prevention Lifeline: 1-800-273-8255 or 988The Trevor Project: 1-866-488-7386Outside the US:International Association for Suicide Prevention lists a number of suicide hotlines by country. Click here to find them.

This is one of the craziest client transformations to date! Katie broke her pelvis 13 years ago when she had her first baby. Ever since then she's been dealing with severe back pain, and bladder leaks bad enough to wear a pad all day. We started slow, but I had her lifting heavier with more intention, working on slowing down, and connecting back to her body and it shifted everything for her.If you feel like it's "too late" to fix pee leaks and back pain, you're wrong. It's never too late, you just need the right strategies in order to heal.If Katie's story hits home for you and you're ready to take the next step, click this link to get startedWork With Me:https://mailchi.mp/chloepufftraining/offers Connect with me on social media: Instagram: @chloepufftraining & @riseradiopod

Overactive bladder affects about 1 in 6 U.S. adults and disrupts sleep, focus, and confidence in daily life Low magnesium levels are strongly linked to higher rates of overactive bladder, with risk climbing steadily as depletion worsens Magnesium helps calm bladder muscles and reduce nerve overactivity, making sudden urges and leaks less frequent Inflammation triggered by magnesium deficiency further irritates bladder tissue and worsens symptoms Restoring magnesium through the right supplements and pairing it with bladder-friendly habits offers a natural, evidence-backed path to relief

October 17, 2025 In this episode, Scott, Mark, and Ray Painter clarify the latest on the Medicare claims hold during the government shutdown, explaining that it applies only to services affected by expired COVID-era provisions like telehealth under traditional Medicare. They also address coding questions on billing for bladder stone removal during robotic prostatectomy—highlighting when to use 51050 vs. 51999—and revisit proper coding for Urocuff procedures following a UnitedHealthcare audit, emphasizing payer-specific strategies and the importance of reviewing operative details and coverage policies.Urology Advanced Coding and Reimbursement SeminarInformation and RegistrationPRS Coding and Reimbursement HubAccess the HubFree Kidney Stone Coding CalculatorDownload NowPRS Coding CoursesFor UrologistFor APPsFor Coders, Billers, and AdminsPRS Billing and Other Services - Book a Call with Mark Painter or Marianne DescioseClick Here to Get More Information and Request a Quote Join the Urology Pharma and Tech Pioneer GroupEmpowering urology practices to adopt new technology faster by providing clear reimbursement strategies—ensuring the practice gets paid and patients benefit sooner.         https://www.prsnetwork.com/joinuptpClick Here to Start Your Free Trial of AUACodingToday.com   The Thriving Urology Practice Facebook group.The Thriving Urology Practice Facebook Group link to join:https://www.facebook.com/groups/ThrivingPractice/ 

Your pelvic floor is ready and waiting for you to break up with these habits:Power-peeing – Going to the bathroom is not a race. Forcing urine out or relieving yourself as fast as you can causes more harm than good to your pelvic floor. Hovering – This seems like a natural solution to avoid germs in public restrooms. But hovering over the toilet tenses your muscles which makes your bladder work harder than it needs to.Peeing “just in case” – Went 15 minutes ago? Maybe going once more is a good idea … or is it? Whether you're heading out for an errand or a road trip, going again “just in case” is training your bladder to go more frequently.  If you're ready to take back control of your bladder, you'll want to listen to the latest episode of The Healthiest You podcast. In Part One of our pelvic floor podcast series, you'll hear from urogynecologist Nabila Noor, MD, and rehabilitation clinical specialist Karen Snowden, PT, DPT, with Lehigh Valley Health Network, part of Jefferson Health. How do you know if you have a pelvic floor disorder? What bathroom habits are harming your pelvic floor? How many times a day should you urinate? Can bladder training help? Which exercises can strengthen your pelvic floor? We answer these questions and more on The Healthiest You podcast this month.Chapters:     · 0:01 - Intro     · 0:17 - About your pelvic floor     · 3:31 - When your pelvic floor changes     · 6:49 - Signs you may have a pelvic floor disorder      · 15:54 - Treatment options     · 17:45 - Bladder leaks and overactive bladder      · 20:26 - How to address overactive bladder     · 23:56 - When to stop drinking before bed     · 29:06 - Bathroom no-nos     · 34:07 - Bladder training

Urinary incontinence affects millions of women, yet many continue to suffer in silence due to stigma or the misconception that it's just a normal part of aging. Bladder control issues can impact women of all ages, and they are highly treatable, and there are real solutions that can help. On this episode of the Healthier You Podcast, Dr. Ashlee Williams welcomes Dr. Nwamaka Fadahunsi, a board-certified urologist at Kaiser Permanente, to discuss the causes of urinary incontinence and the many tools available to treat it. Dr. Fadahunsi explains the differences between stress and urge incontinence, debunks common myths, and offers practical guidance on what women can do at home. She also outlines the full range of treatment options, including physical therapy, medications, and outpatient procedures, helping women regain control and confidence without relying on pads or assuming surgery is the only answer.  Learn more about Nwamaka Fadahunsi, MD 

Many people with Parkinson's disease experience urinary or bladder issues at some point in their journey. These symptoms can take different forms and may affect people differently based on gender. Recognizing the signs is the first step toward understanding how to manage them and when to seek care.   In this episode, Dr. Ankita Gupta, MD, MPH, FACOG, a urogynecologist at University of Louisville Hospital, talks about common bladder issues in Parkinson's, such as urinary frequency, urgency, and nocturia. She explains how these symptoms can affect quality of life and even contribute to social isolation, and she highlights treatment options that can help manage them.   Follow and rate us on your favorite podcast platform to be notified when there's a new episode! Let us know what other topics you would like us to cover by visiting parkinson.org/feedback.

No, it's not just a "weak pelvic floor."In fact, there's a surprising number of factors that contribute to bladder issues. Everything from the bra you wear to your menstrual cycle.Today we unpack what's causing those issues and how to mitigate symptoms so you can live pee-freeWork With Me:https://mailchi.mp/chloepufftraining/offers Connect with me on social media: Instagram: @chloepufftraining & @riseradiopod

Do you get the blues when the weather turns cool? In this episode, Dr. Motley tackles seasonal depression from a TCM perspective. In Traditional Chinese Medicine, the heart is connected to the kidneys and bladder, so if you feel that you're not your best self in the colder months, pay attention to signs of bladder issues.  Show Notes: ⬇️ For UTI testing: https://microgendx.com/ For kidney issues: Uva Ursi https://shorturl.at/QTKEK Your Seasonal Depression Recommendations: Sunshine Infrared Sauna Mineral Support (check out BEAM Minerals. You can get 20% off with code DRMOTLEY - https://shorturl.at/ySEiA) Multivitamins: Thorne Research https://www.thorne.com/products, and Xymogen EFT - https://www.thetappingsolution.com/ Neuroemotional Technique - https://netmindbody.com/ If you love this content and want more, check out Doctor Motley's YouTube Channel! ------  Follow Doctor Motley Instagram TikTok Facebook Website ------  *Do you have more questions for Doctor Motley about seasonal depression? Do you want to get deeper into his material? Take advantage of ALL Doctor Motley's clinical experience, with his membership where you can get the most out of your health and help the people you love. Check it out for free for 15 days: doctormotley.com/15 *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 *Charge your cells with pure antioxidant power! Liposomal supplementation has been proven deeply effective and LivOn Labs got there first. Get 10% off your liposomal supplements with code DROMTLEY at livonlabs.com Your Seasonal Depression Recommendations: Sunshine Infrared Sauna Mineral Support (check out BEAM Minerals. You can get 20% off with code DRMOTLEY - https://shorturl.at/W8MO5⁠) Multivitamins: Thorne Research https://www.thorne.com/products, and Xymogen https://shorturl.at/JIowR⁠ EFT - https://www.thetappingsolution.com/ Neuroemotional Technique - https://netmindbody.com/ If you love this content and want more, check out Doctor Motley's YouTube Channel! ------  Follow Doctor Motley Instagram: https://www.instagram.com/doctormotley https://www.tiktok.com/@doctormotley Facebook: https://www.facebook.com/doctormotley/ Website: https://doctormotley.com ------  *Do you have more questions for Doctor Motley about seasonal depression? Do you want to get deeper into his material? Take advantage of ALL Doctor Motley's clinical experience, with his membership where you can get the most out of your health and help the people you love. Check it out for free for 15 days: doctormotley.com/15 *If you want to work with Dr. Motley virtually, you can book a discovery call with his team here: https://drmotleyconsulting.com/schedule-1333-7607 *Charge your cells with pure antioxidant power! Liposomal supplementation has been proven deeply effective and LivOn Labs got there first. Get 10% off your liposomal supplements with code DROMTLEY at livonlabs.com

Back from speaking and a few live events, Sally shares about the importance of human connection & the longing we all have for community. Other Episode Highlights:Fall is here and so are the allergiesTrailfest & Mammoth 200 chatHiking for ice-creamSpeaking in MissouriImpactful stories and people Sally met in KY, TN, & MOKids and families Sally connected with Running with othersEarly morning coffee & gym routineConnect with Sally on LINKEDIN & on SUBSTACKGoing to be a Javelina this year? Let us know what you will be doing out there! Send us an email at contact@sallymcrae.comAll links, discounts, and ways to support the podcast are here.⁠⁠⁠⁠⁠⁠⁠Choose Strong Book ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sally McRae Strength App⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Choose Strong Podcast YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Sally McRae YouTube⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Choose Strong Merch ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Bare Performance Nutrition⁠⁠⁠⁠⁠⁠⁠ Code: SALLY⁠⁠⁠⁠⁠⁠⁠Choose Strong Strava Group⁠⁠⁠⁠⁠⁠⁠Want to send us mail? Here is the address if you want to say hi!6771 Warner Ave. P.O. Box 2051Huntington Beach, CA 92647Episode Sponsors:Boncharge: boncharge.com w/ code SALLY to save 15%Janji: Go to ⁠⁠⁠⁠⁠janji.com ⁠⁠⁠⁠⁠and use code CHOOSESTRONG for 10% offPlan to Eat: plantoeat.com/sally for 25% off an annual subscription

In this episode of Mining the Comments, Coach Cristian addresses how hyper arousal affects the bladder, especially in those with insomnia. He shares personal experiences, explains the nervous system's role, and emphasizes the importance of acceptance in alleviating symptoms. Coach Cristian encourages viewers to respond gently and with patience to their body's signals. If you're new here and like what you've seen so far, you'll want to download our FREE 'Off-to-Dreamland' e-booklet. Simply head over to https://www.thesleepcoachschool.com and click the link at the tippy top. Happy reading!  If you're ready to leave insomnia for good, check out our coaching options. Head over to www.thesleepcoachschool.com and click on GET SLEEP in the menu. The Insomnia Immunity program is perfect if you like learning through video and want to join a group on your journey towards sleeping well. BedTyme is ideal if you like to learn via text and have a sleep coach in your pocket. The 1:1 Zoom based program is for you if you like to connect one on one with someone who has been where you are now.  Do you like learning by reading? If so, here are two books that offer breakthroughs! Tales of Courage by Daniel Erichsen https://www.amazon.com/Tales-Courage-Twenty-six-accounts-insomnia/dp/B09YDKJ3KX Set it & Forget it by Daniel Erichsen https://www.amazon.com/Set-Forget-ready-transform-sleep/dp/B08BW8KWDJ  Would you like to become a Sleep Hero by supporting the Natto movement on Patreon? If so, that's incredibly nice of you

Benign prostatic hyperplasia (BPH) impacts many men at some point as they age. Ramsay Kuo, MD, discusses why treatment is so important, and the growing number of options men have to improve quality of life and prevent irreversible bladder damage.You can also watch the video recording on our Vimeo channel here.For more health tips & news you can use from experts you trust, sign up for Sarasota Memorial's monthly digital newsletter, Healthe-Matters.

Study Discovers Increased Cancers After MRNA Vaccines, Bret Weinstein- Covid & mRNA: Harms and Damages Exposed Bret Weinstein- Covid & mRNA: Harms and Damages Exposed (NEW!) REMINDER: CDC Didn't Track VAERS Safety Signals John Campbell- Increased cancers after mRNA vaccines   Study- Covid & mRNA: Harms and Damages Exposed (NEW!) | DarkHorse https://youtu.be/zkrbZmYuRoY?si=_0yO0y5ftLacoVJ1 Bret Weinstein 512K subscribers 25,699 views Sep 5, 2025 A new article on the harms and hazards of both SARS-CoV2 and the mRNA biologics said to counter the virus. Full Episode: https://youtube.com/live/wQWkKrM3Dt8 Mentioned in this segment: Zywiec et al 2025. COVID-19 Injections: Harms and Damages, a Non-Exhaustive Conclusion. Journal of American Physicians and Surgeons, 30(3): https://jpands.org/vol30no3/zywiec.pdf ***** Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.com Heather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.com Our book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned) Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org   REMINDER: CDC Didn't Track VAERS Safety Signals | DarkHorse https://youtu.be/u3UAyr6s7xc?si=VUoenskCyMdViArS Bret Weinstein 512K subscribers 16,906 views Sep 5, 2025 RFK Jr. fires the new director, after which other CDC officials resign, and eight former directors of the CDC pen a letter to the New York Times arguing that Kennedy is a hazard to our health. Bret Weinstein and Heather Heying discuss "The Plot Against Kennedy" in Episode 292 of The Evolutionary Lens. Full Episode: https://youtube.com/live/wQWkKrM3Dt8 Mentioned in this segment: NYT op-ed #2 from former CDC directors: We Ran the C.D.C.: Kennedy Is Endangering Every American's Health: https://www.nytimes.com/2025/09/01/op... Bret and Heather 132nd DarkHorse Podcast Livestream: 50 States not in a Roe https://youtube.com/live/usP2D_qGUZs CDC didn't monitor VAERS for COVID safety signals (June 2022): https://childrenshealthdefense.org/de...   Increased cancers after mRNA vaccines Watch this video at- https://youtu.be/3dnIGqUlluc?si=sDbAdXTgOsCiCLev Dr. John Campbell 3.25M subscribers 143,152 views Sep 5, 2025 COVID-19 vaccination, all-cause mortality, and hospitalization for cancer: 30-month cohort study in an Italian province https://pubmed.ncbi.nlm.nih.gov/40881... https://pmc.ncbi.nlm.nih.gov/articles... https://www.thefocalpoints.com/p/brea... The rate of first hospitalization for cancer of any site Unvaccinated group: 0.85% Vaccinated group (one or more doses): 1.15% N = 296,015 population Hospital admission with a cancer diagnosis, 3,124 (p less than 0.001). Vaccination with at least one dose Colon-rectal cancer HR: 1.34 Breast cancer HR: 1.54 Bladder cancer HR: 1.62 After three or more vaccine doses Breast cancer HR: 1.36 Bladder cancer HR: 1.43 All significant After one dose (180 days after) Rate of first hospital admissions for cancers All cancers: up 23% significant Colorectal: up 34% significant Lung: down = 10% Breast: up 54% significant Uterine: up = 75% Ovarian: up = 65% Prostate: up = 1% Bladder: up 62% significant Thyroid: up =58% Haematological: up = 33% After three dose (180 days after administration of third dose) All cancers: up = 9% Colorectal: up = 14% Lung: down = 5% Breast: up=36% significant Uterine: up = 20% Ovarian: up = 86% Prostate: down = 3% Bladder: up=43% significant Thyroid: down = 3% Haematological: up = 5% More about the study Population-wide cohort analysis Evaluating the risk of all-cause death and cancer hospitalization by SARS-CoV-2 immunization status. National Health System official data, entire population, Pescara province, Italy Followed from June 2021 (six months after the first vaccination) to December 2023. 296,015 residents aged ≥11 years Hospital admission with a cancer diagnosis, 3,124 16.6% were unvaccinated 83.3% received ≥1 dose 62.2% ≥3 doses. Compared with the unvaccinated, those receiving ≥1 dose showed a significantly lower likelihood of all-cause death Cancer hospitalization was significant only among the subjects with no previous SARS-CoV-2 infection Some cancer risks went down after 1 year (relative to 180 days) (But breast, ovarian and bladder went up at one year relative to 180 days after 1 vaccine dose) Given that it was not possible to quantify the potential impact of the healthy vaccinee bias and unmeasured confounders, these findings are inevitably preliminary.  

Send us a textHave you ever wondered why urinary issues seem to affect women differently than men? The answer lies in our unique anatomy and hormonal makeup — factors that make female urinary health both fascinating and complex.Dr. Holly Thacker takes listeners on a comprehensive journey through the most common urologic conditions affecting women during Urology Awareness Month. From the annoying but potentially dangerous urinary tract infections to the embarrassing reality of pelvic organ prolapse that affects up to one in eight women, this episode breaks down what's happening and why."Everyone needs a bladder that works," Dr. Thacker emphasizes as she explores how bladder health connects to overall wellness and quality of life. She tackles taboo topics with medical precision while offering practical advice for prevention and management. You'll learn why maintaining pelvic floor strength matters even if you've never been pregnant, how hormonal changes dramatically affect urologic health, and why sexual function is inextricably linked to bladder health.Subscribe to the Speaking of Women's Health Podcast wherever you listen to podcasts and visit speakingofwomenshealth.com for more resources on taking charge of your health.Support the show

Contributor: Travis Barlock MD Educational Pearls: Meningitis retention syndrome is a relatively novel and rare clinical condition Aseptic meningitis + acute urinary retention One study reports an incidence of about 8% in patients with acute aseptic meningitis Clinical presentation Typical meningeal symptoms including fever, stiff neck, and headache Urinary retention occurs about one week after initial symptoms Potential pathophysiology Immune-mediated dysfunction of the central nervous system Detrusor muscle underactivity from inflammation of the spinal cord Management Supportive care Bladder decompression References Hiraga A, Kuwabara S. Meningitis-retention syndrome: Clinical features, frequency and prognosis. J Neurol Sci. 2018;390:261-264. doi:10.1016/j.jns.2018.05.008 Pellegrino F, Funiciello E, Pruccoli G, et al. Meningitis-retention syndrome: a review and update of an unrecognized clinical condition. Neurol Sci. 2023;44(6):1949-1957. doi:10.1007/s10072-023-06704-0 Summarized & Edited by Jorge Chalit, OMS4 Get your tickets to Tox Talks Event, Sept 11, 2025: https://emergencymedicalminute.org/events-2/ Donate: https://emergencymedicalminute.org/donate/