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I got to hang out with Dr. Bruce Damer recently on the beach at Kaplankaya in Turkey. Bruce is an amazing scientist, a humble guy. Who has spent his whole career trying to figure out how did life begin on Earth? He and his co-conspirator Dr. David Deamer have figured out something that not only works as a hypothesis for how life began on Earth – but they've been able to reproduce it – in hot Springs. Bruce is also a brave pioneer of using psychedelics to change his own mind, to change his own life, and to help him with insights for scientific discovery. He has also since created The Center for MINDS, which is an organization devoted to advancing scientific discovery. In part, by helping folks use psychedelics and learn about using psychedelics to go places their minds just don't want to go otherwise. This is a bit controversial and has been taboo for my entire life. I think it's very important area to research. I really appreciate the people who are coming out – risking their own careers and the backlash of bias that people have – to help us figure out what's possible with this frontier in science. Bruce has really opened up to share his own life experience with you guys and I'm really thankful to him for that. Important Links: Center for Minds BIOTA Institute About Bruce Damer BIOTA Institute Director and Chief Scientist Dr. Bruce Damer has spent his life pursuing two great questions: how did life on Earth begin, and how can we give that life (and ourselves) a sustainable pathway into the cosmos? He conceived of BIOTA in 1996 and guided it through its first two decades of evolution in which it hosted four conferences and a podcast (hosted by Tom Barbalet) on the use of digital spaces to simulate evolution and natural systems. A decade of scientific research with his collaborator Prof. David Deamer at the UC Santa Cruz Department of Biomolecular Engineering resulted in the Hot Spring Hypothesis for an Origin of Life published in the journal Astrobiology in 2019 . In 2021, with growing global collaboration around the hypothesis, he determined that BIOTA was ready for its new mission: raising grants for students and young scientists to test this scenario for life's origins and explore its implications for humanity. Dr. Damer also has a long career working with NASA on mission simulation and design and recently co-developed a spacecraft to utilize resources from asteroids. He is an avid collector of vintage computing hardware in his DigiBarn Computer Museum and enjoys a fine life with his partner Kathryn Lukas, 3 cats and one adorable chihuahua in their Gandalf-inspired house high up in the Santa Cruz redwoods.
Jackie Dobrinska and Bruce Damer chat about insight into ourselves and outsight into the world in this recording from the Ram Dass Explorers Club.The Ram Dass Explorers Club is a free virtual group wherein members delve into pivotal movements within the psychedelic renaissance while paying homage to the enduring legacy of Ram Dass. Join HERE to embark on explorations of expanded consciousness, guided by the themes of awe, transcendence, union, and beyond.Today's episode is brought to you by BetterHelp. Give online therapy a try at betterhelp.com/beherenow and get on your way to being your best self.In this episode, host Jackie Dobrinska speaks with Bruce Damer about:Ram Dass' work and how he continues to inspire othersHow Bruce came to know Ram DassThe way that Ram Dass hits on the center of thingsAlbert Einstein and thought experimentsEntering flows of connection and timeThe etymology of psychedelicsHow we create our own realitiesComing into embodied wisdom and the serpent of the internetRam Dass as a beacon to the reality we needNavigating psychedelics and having adequate preparationKnowing that we are always held by loveAbout Dr. Bruce Damer:Dr. Bruce Damer is a scientist, psychonaut, and humanitarian. Dr. Damer is Chief Scientist at BIOTA Institute, UC Santa Cruz. He is an astrobiologist working on the science of life's origins, spacecraft design, psychedelics and genius. Dr. Bruce has spent his life pursuing two great questions: how did life on Earth begin, and how can we give that life (and ourselves) a sustainable pathway into the cosmos? A decade of scientific research with his collaborator Prof. David Deamer at the UC Santa Cruz Department of Biomolecular Engineering resulted in the Hot Spring Hypothesis for an Origin of Life published in the journal Astrobiology in 2019. Dr. Damer also has a long career working with NASA on mission simulation and design and recently co-developed a spacecraft to utilize resources from asteroids. You can keep up with Dr. Bruce Damer on Twitter.About Jackie Dobrinska:Jackie Dobrinska is the Director of Education, Community & Inclusion for Ram Dass' Love, Serve, Remember Foundation and the current host of Ram Dass' Here & Now podcast. She is also a teacher, coach, and spiritual director with the privilege of marrying two decades of mystical studies with 15 years of expertise in holistic wellness. As an interspiritual minister, Jackie was ordained in Creation Spirituality in 2016 and has also studied extensively in several other lineages – the plant-medicine-based Pachakuti Mesa Tradition, Sri Vidya Tantra, Western European Shamanism, Christian Mysticism, the Wise Woman Tradition, and others. Today, in addition to building courses and community for LSRF, she leads workshops and coaches individuals to discover, nourish and live from their most authentic selves. Learn more about Jackie's work at asimplevibrantlife.com.“We can create our realities. We'll determine whether we are constricted or opened at every moment by our choices of what we produce for our fellow humans.” – Bruce DamerSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Pairing science and mysticism, Astrobiologist Dr. Bruce Damer visits Mindrolling for a sweeping discussion on the interconnected nature of the world.This week on Mindrolling, Raghu Markus and Dr. Bruce Damer dig into:Interconnected fields within natureGroup connection and relationshipPatterned memory in spaceAncestral memories, spirit, and the research of phenomenaBecoming the experience and playing with thought experimentsAlbert Einstein and scientific mysticismCollective intelligence and receiving downloadsThe operating system of the living worldRam Dass, Neem Karoli Baba, and mystical storiesMoving beyond the logical mind and tapping into possibilitiesGroup field as the antidote to separation, fear, and anxietyThe efficacy of psychedelic medicineThe revealing that comes after individual healingDr. Bruce Damer's experience on AyahuascaDeath writing the code of lifeEmbodiment and the ‘gooeyness' of being human About Dr. Bruce Damer:Dr. Bruce Damer is Chief Scientist at BIOTA Institute, UC Santa Cruz. He is an astrobiologist working on the science of life's origins, spacecraft design, psychedelics and genius. Dr. Bruce has spent his life pursuing two great questions: how did life on Earth begin, and how can we give that life (and ourselves) a sustainable pathway into the cosmos? A decade of scientific research with his collaborator Prof. David Deamer at the UC Santa Cruz Department of Biomolecular Engineering resulted in the Hot Spring Hypothesis for an Origin of Life published in the journal Astrobiology in 2019. Dr. Damer also has a long career working with NASA on mission simulation and design and recently co-developed a spacecraft to utilize resources from asteroids. You can keep up with Dr. Bruce Damer on Twitter.“The common ancestor of all life is not a little, individual, primitive cell that is duking it out alone in the universe. It is actually a communal mass that is a body in growth, a body in adaptation.” – Dr. Bruce DamerSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Jim talks with Bruce Damer about genius and the use of psychedelics for creative thinking. They discuss the roots of genius, the discovery of fire, Einstein's four great discoveries, building blocks of genius, endotripping vs exotripping, set, setting, & setup, the danger of over-relying on LLMs for knowledge, geniuses in the scanner, crosstalk in the brain, the prepared mind, Bruce's lifelong experience of endotripping, rapid retripping, lucid dreaming, getting psilocybin from Terence McKenna, ayahuasca, Steve Jobs's LSD experience, external constraints, Bruce's epiphany about the origins of life, hypothesizing as a non-rational process, the stoned ape theory, psychedelics in Eleusis, human brain sizes & assisted birth, hypnagogic trip states, casualties of the early psychedelic era, a call for serious practitioners, a proposal for string theorists, Charles Manson & the importance of screening for wisdom, the increasing need for genius, and much more. Episode Transcript Bruce Damer (personal website) The BIOTA Institute JRS EP 167 - Bruce Damer on the Origins of Life JRS EP 171 - Bruce Damer Part 2: The Origins of Life – Implications Lucid News Canadian-born Dr. Bruce Damer has spent his life pursuing two questions: how did life on Earth begin? and how can we give that life (and ourselves) a sustainable pathway into the future and a presence beyond the Earth? A decade of laboratory and field research with his collaborator Prof. David Deamer at UCSC and teams around the world resulted in the Hot Spring Hypothesis for an Origin of Life, published in Scientific American in 2017 and the journal Astrobiology in 2020. The scenario has now passed its first key experimental tests in the laboratory and at volcanic hot springs around the world and has emerged as a leading contender for a general theory of abiogenesis. Implications of the work are now spreading through evolutionary biology, philosophy, AI and the search for life beyond Earth. New work with collaborators has proposed the urability framework, how life can start on many different worlds, and addresses some aspects of the Fermi Paradox.
Jim continues his discussion with Bruce Damer on the origins of life. They discuss Darwin's "warm little pond" hypothesis, hydrothermal fields as selection engines, wet-dry cycling, proto-cells, competing theories, implications of the hypothesis, niche construction theory, the origin of life as mostly collaborative, the probability interaction process (PIM) model, effects of crowding together, sharing results, the emergence of memory, PIM as a general principle of emergence, Covid-19 as an example of amplification, applying PIM to civilizational health, the loss of face-to-face community membranes in late-stage capitalism, "harthology," applying PIM to the search for artificial general intelligence (AGI), collaborations with Ben Goertzel & Google's AI group, protocellular systems as general learning systems, creating a genesis engine, the Fermi paradox & the Drake equation, the new concept of urability, the low probability of sustaining life long enough to reach complexity, new data from Mars & exoplanet atmospheres, the possibility that Earth is extremely rare, bringing the galaxy to life, creating hundreds of thousands of warm little ponds using asteroids, and much more. JRS EP 167 - Bruce Damer on the Origins of Life BIOTA Institute JRS EP140 - Robin Dunbar on Friendship JRS Currents 072: Ben Goertzel on Viable Paths to True AGI The Open Cognition Project (OpenCog) Tierra (Wikipedia) Wonderful Life: The Burgess Shale and the Nature of History, by Stephen Jay Gould SETI Institute Canadian-born Dr. Bruce Damer has spent his life pursuing two questions: how did life on Earth begin? and how can we give that life (and ourselves) a sustainable pathway into the future and a presence beyond the Earth? A decade of laboratory and field research with his collaborator Prof. David Deamer at UCSC and teams around the world resulted in the Hot Spring Hypothesis for an Origin of Life, published in Scientific American in 2017 and the journal Astrobiology in 2020. The scenario has now passed its first key experimental tests in the laboratory and at volcanic hot springs around the world and has emerged as a leading contender for a general theory of abiogenesis. Implications of the work are now spreading through evolutionary biology, philosophy, AI and the search for life beyond Earth. New work with collaborators has proposed the urability framework, how life can start on many different worlds, and addresses some aspects of the Fermi Paradox.
Listen Now to Dr. Bruce Damer 12.05.2022 One of our science stories this week is about new discoveries of more recent volcanism on Mars, suggesting that a warmer climate there may have led to the creation of life there. We speak with evolutionary scientist Bruce Damer about the significance of these latest discoveries. He also brings us up-to-date with his latest work with David Deamer and Francesca Carey, on the introduction of a new concept, ‘urability,’ a property of planets that can support the beginnings of life as we understand it. Bruce also speaks of his origin of life work at the Fly Hot Springs, a place we know, curiously, from visits to Burningman, and how AI can play a role in understanding our biological evolution. Enjoy!
Jim talks with Bruce Damer about the origins of life. They discuss what Earth was like 4 billion years ago, how the oceans formed, the new concept of urability, the distinction between supporting life & bringing it into being, the source of organic building blocks, combinatorial selection, the ocean vents theory vs the warm little pond hypothesis, the Murchison meteorite, wet-dry cycling, the water problem, using stromatolites & other natural analogs to test conjectures, finding the oldest evidence of life in a hot spring setting, shouting matches as evidence of paradigm shifts, what warm pools were made of, a one-pot solution that's testable at every stage, the source of vesicles, why the ocean is implausible as a starting point, chemical gardens, the great search for the origins of emergence, semipermeable membranes, "sludge of progenitor," the jacuzzi origin of life, the origin of life as a communal unit, the ratchet to greater complexity, thermal change in near-real time, the error catastrophe in evolutionary computing, actual experiments being performed, the Fermi paradox & astrobiological implications, a hot spring on Mars, urability scores, the Drake equation, where complexity theory meets biology, the rarity of complex life & the responsibility that comes with it, bringing the universe to life, and much more. Episode Transcript JRS EP40 - Eric Smith on the Physics of Living Systems Biota.org "The Hot Spring Hypothesis for an Origin of Life," by Bruce Damer & David Deamer JRS EP18 - Stuart Kauffman on Complexity, Biology & T.A.P. "The Water Paradox and the Origins of Life" (Nature), by Michael Marshall "Urability: A Property of Planetary Bodies That Can Support an Origin of Life," by David Deamer and Bruce Damer Canadian-born Dr. Bruce Damer has spent his life pursuing two questions: how did life on Earth begin? and how can we give that life (and ourselves) a sustainable pathway into the future and a presence beyond the Earth? A decade of laboratory and field research with his collaborator Prof. David Deamer at UCSC and teams around the world resulted in the Hot Spring Hypothesis for an Origin of Life, published in Scientific American in 2017 and the journal Astrobiology in 2020. The scenario has now passed its first key experimental tests in the laboratory and at volcanic hot springs around the world and has emerged as a leading contender for a general theory of abiogenesis. Implications of the work are now spreading through evolutionary biology, philosophy, AI and the search for life beyond Earth. New work with collaborators has proposed the urability framework, how life can start on many different worlds, and addresses some aspects of the Fermi Paradox.
Listen Now to Dr. Bruce Damer 12.15.2020 One of our favorite guests, Bruce brings us up to date on the latest asteroid return missions, heralding a new era in our ability to collect samples from off planet in our solar system and bring them back to Earth. We delve a bit into the adventures of Elon Musk’s Starship, and Bruce’s Origin of Life research, including his inclusion in a feature article on the topic in the latest issue of Nature, the scientific journal. We also discuss mRNA and why that is such a breakthrough approach for vaccines, understanding the creation of life via protocells, the rise of human consciousness as a kind of slime mold in the Gaian field, and our role as imaginal cells in the field. We discuss his collaboration with Dr. David Deamer, and the future of online collaboration with the next generation of scientists. Mrs. Future also reminds us of the ‘Christmas Star’ that will appear next week, for the first time in hundreds of years. Enjoy! Dr. Bruce Damer, looking up!
In this episode of CLR, Join Marc Caron and Stephen Gray as we speak with Dr. Bruce Damer, one of this years speakers at the Virtual Spirit Plant Medicine Conference, this October 23-25, 2020. Dr. Damer is an Astrobiologist collaborating with Prof. David Deamer in the Department of Biomolecular Engineering, UC Santa Cruz on the […] The post The Dawning of Planetary Metta-Intelligence with Dr. Bruce Damer appeared first on Conscious Living Radio.
Research professor David Deamer's work led to the exciting discovery of lipid material in meteorites that are capable of “self-assembly” into membranous material, a key step in understanding the first cell membrane formation. He explains this and other life-origin elements, such as What scientists think may have happened in “hot little pools” around volcanic activity four billion years ago and how they are recreating these pools in the lab, Additional elements of biomolecular engineering research that enabled their design of these experiments that includes findings of stromatolites in Australia, and Next steps in his work on the road towards the first developments of metabolism and RNA catalyzation. David Deamer is a Research Professor of Biomolecular Engineering at UC Santa Cruz. In this podcast he begins with the early days of his research, including a sabbatical in England when he worked with Dr. Alec D. Bangham, the inventor of liposomes, which are essentially drug delivery compounds made from lipids. Deamer and Bangham realized no one had figured out where membranes came from in the beginnings of life. That began a decade-long research project that included meteorites, lipids, astrobiology, and biomolecular engineering research. After he explains this discovery of “self-assembly” of membrane formation from these meteor lipids, he describes his current research, including steps toward understanding how a cell membrane might surround these other cell elements. He describes how monomers lead to polymers, which lead to amino acids and how nucleic acids eventually arise. He also gets specific about the steps of life and how his research now anticipates the beginnings of metabolism and RNA catalyzation. For more information, he advises searching the NASA website for astrobiology information. In addition, a journal called Astrobiology can be found at major academic research libraries and Nature and Science magazines publish exciting papers as well.
Here’s my latest audio piece on David Deamer that will be on KSQD.org at 7:30 pm on the Cutting Edge Radio Show. Our talk ranges from what is a nanopore and how does this DNA/RNA sequencer work, entrepreneurship, origins of life, helping people with Huntington’s Disease and much more. Give it a listen. You might […] The post David Deamer appeared first on Artist on Art.
Dave is back! We speak again about French philosopher Gilles Deleuze. This time we try to crack one of his most famous works Difference and Repetition. We talked about some very abstract concepts such as space, time, motion, representation and identity, and Deleuze’s three syntheses of time, but Dave does a brilliant of job of coherently explaining this very challenging book and the ‘sheet of black night’ that confronts us all. Dr David Deamer is a writer and free scholar associated with Manchester Metropolitan University, UK. His interests lie at the intersection of cinema and culture with theory, history, and politics, centring on the philosophy of Gilles Deleuze, Henri Bergson, and Friedrich Nietzsche. He is the author of Deleuze’s Cinema Books: Three Introductions to the Taxonomy of Images (EUP, 2016); and Deleuze, Japanese Cinema and the Atom Bomb: The Spectre of Impossibility (Bloomsbury, 2014). He has published here and there in various edited collections and journals, and his latest essay – available free on the Film-Philosophy journal home page – is ‘Deleuze’s Three Syntheses Go to Hollywood: The Tripartite Cinema of Time Travel, Many Worlds and Altered States‘ (Film-Philosophy v23i3 EUP, 2019). You can find out more about David on his homepage. You can listen to more free content from the Thales' Well podcast on TuneIn Radio, Player FM, Stitcher and Podbean. You can also download their apps to your smart phone and listen via there. You can subscribe for free on iTunes. Please leave a nice review. You can follow me on Twitter: @drphilocity
Bruce Damer, PhD, is coauthor with David Deamer, of a new theory on the origins of life that was featured in a Scientific American cover story in 2017. His professional interests also include space exploration, virtual reality, and entheogens. He is author of Avatars: Exploring and Building Virtual Worlds on the Internet. His website is … Continue reading "What is Consciousness? with Bruce Damer"
Bruce Damer, PhD, is coauthor with David Deamer, of a new theory on the origins of life that was featured in a Scientific American cover story in 2017. His professional interests also include space exploration, virtual reality, and entheogens. He is author of Avatars: Exploring and Building Virtual Worlds on the Internet. His website is … Continue reading "Human Destiny with Bruce Damer"
Scottish doctor, writer, speaker, and outspoken cholesterol sceptic Malcolm Kendrick is back on the podcast this week. He continues to challenge the widespread use of statin medications, despite being targeted personally and professionally by those opposing his message. Since we last talked he has authored a new book, A Statin Nation: Damaging Millions in a Brave New Post-health World, elucidating his position against mainstream medicine’s rampant cholesterol-lowering tactics. On this podcast, Dr. Kendrick describes in detail exactly what he believes drives the process of cardiovascular disease, informed from 35 years of research on the subject. He explains specifically why cholesterol has been misunderstood, and how medicine got it wrong. We discuss corruption in medical research and the money supporting the status quo, and Dr. Kendrick shares some of the best ways to avoid heart disease (which have little to do with diet!). Here’s the outline of this interview with Malcolm Kendrick: [00:00:07] Our first podcast with Malcolm Kendrick: Why Cholesterol Levels Have No Effect on Cardiovascular Disease (And Things to Think about Instead). [00:00:30] Book: A Statin Nation: Damaging Millions in a Brave New Post-health World, by Dr. Malcolm Kendrick. His previous two books: Doctoring Data and The Cholesterol Con. [00:02:00] Causes vs processes. [00:03:40] History behind his journey and questioning authority. [00:07:30] Articles written by Elspeth Smith. [00:09:00] Karl Rokitansky’s paper discussing an alternative way of looking at CVD: A manual of pathological anatomy, Vol. 4. Day GE, trans. London: Sydenham Society, 1852:261; in print here. [00:09:06] Rudolf Virchow, researcher who pointed to cholesterol in artery walls. [00:10:55] Researcher Nikolai N. Anichkov: fed rabbits a high-cholesterol diet and cholesterol appeared in their arteries (sort of). [00:12:07] Ancel Keys; blaming saturated fat. [00:14:11] France - highest saturated fat consumption, lowest rate of CVD. Georgia - lowest sat fat consumption, highest rate of CVD. See graph, here. [00:15:16] International Network of Cholesterol Skeptics (THINCS). Study: Ravnskov, Uffe, et al. "Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review." BMJ open 6.6 (2016): e010401. [00:16:50] Pleiotropic effects of statins. [00:17:29] Movie: 12 Angry Men (1957). [00:20:30] Robert Ross - response to injury hypothesis; Study: Ross, Russell, John Glomset, and Laurence Harker. "Response to injury and atherogenesis." The American journal of pathology 86.3 (1977): 675. [00:20:40] TV show: Stranger Things. [00:22:31] Infectious disease hypothesis. [00:22:52] Analogy of rust in the paint of a car; Sickle Cell Disease as an example. [00:27:12] 14-year old boy with Sickle Cell and atherosclerosis; Study: Elsharawy, M. A., and K. M. Moghazy. "Peripheral arterial lesions in patient with sickle cell disease." EJVES Extra 14.2 (2007): 15-18. [00:28:57] Endothelial progenitor cells, produced in the bone marrow, discovered in 1997. [00:29:31] Pig study of endothelial turnover: Caplan, Bernard A., and Colin J. Schwartz. "Increased endothelial cell turnover in areas of in vivo Evans Blue uptake in the pig aorta." Atherosclerosis 17.3 (1973): 401-417. [00:31:48] Vitamin C's role in maintaining collagen and blood vessels. [00:33:08] Lp(a) molecules - patching cracks in the artery walls. [00:33:42] Depriving guinea pigs of vitamin C caused atherosclerosis; Study: Willis, G. C. "The reversibility of atherosclerosis." Canadian Medical Association Journal 77.2 (1957): 106. [00:34:24] Linus Pauling - said CVD was caused by chronic low-level vitamin C deficiency. [00:35:53] What else damages endothelial cells? Many things, including smoking, air pollution, high blood sugar, Kawasaki disease, sepsis/infection. [00:41:19] Glycocalyx; Nitric oxide. [00:43:30] Health benefits of sun exposure. [00:44:26] Biomechanical stress (blood pressure) - atherosclerosis in arteries but not in veins. [00:47:57] Things that interfere with repair: steroids, vascular endothelial growth factor (VEGF) inhibitors. [00:55:00] The effects of stress on the cardiovascular system. [00:57:55] Red blood cells are what brings cholesterol into blood clots. [00:58:59] Cholesterol crystals in atherosclerotic plaques come from red blood cells. Study: Kolodgie, Frank D., et al. "Intraplaque hemorrhage and progression of coronary atheroma." New England Journal of Medicine 349.24 (2003): 2316-2325. [01:00:55] Very low-density lipoproteins (VLDLs) are procoagulant; High-density lipoprotein (HDL) is anticoagulant. [01:03:46] Familial hypercholesterolemia (FH); Factor VIII. [01:08:15] Cholesterol-lowering pharmaceuticals; Repatha. In the clinical trial, the total number of cardiovascular deaths was greater in the Repatha group than the placebo group. Study: Sabatine, Marc S., et al. "Evolocumab and clinical outcomes in patients with cardiovascular disease." New England Journal of Medicine 376.18 (2017): 1713-1722. [01:09:34] David Deamer, biologist and Research Professor of Biomolecular Engineering. [01:10:05] Karl Popper, philosopher. [01:10:28] Bradford Hill’s Criteria for Causation. [01:13:52] Michael Mosley, BBC journalist. [01:16:40] Statin denialism - an internet cult with deadly consequences? [01:19:18] The money behind the statin and low-fat industries. [01:20:06] Margarine; Trans-fatty acids, banned in several countries. [01:24:37] The impact of food; The focus on food to the exclusion of other pillars of health. [01:26:38] Dr. Phil Hammond; CLANGERS [01:28:21] Avoiding internet attacks. [01:32:00] ApoA-1 Milano. Original study: Nissen, Steven E., et al. "Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial." Jama 290.17 (2003): 2292-2300. [01:33:05] The Heart Protection (HPS) Study in the UK: Heart Protection Study Collaborative Group. "MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebo controlled trial." The Lancet 360.9326 (2002): 7-22. [01:33:36] Scandinavian Simvastatin Survival Study (4S) Scandinavian Simvastatin Survival Study Group. "Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)." The Lancet 344.8934 (1994): 1383-1389. [01:33:49] West of Scotland Coronary Prevention Study (WOSCOPS): Shepherd, James, et al. "Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia." New England Journal of Medicine 333.20 (1995): 1301-1308. [01:34:21] National Institute of Health’s ALLHAT-LLT trial: Officers, A. L. L. H. A. T. "Coordinators for the ALLHAT Collaborative Research Group: Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs. usual care: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT)." JAMA 288.23 (2002): 2998-3007. [01:34:50] 2005 - Regulations guiding clinical trials changed. [01:35:14] Negative antidepressant studies not published; Study: Turner, Erick H., et al. "Selective publication of antidepressant trials and its influence on apparent efficacy." New England Journal of Medicine 358.3 (2008): 252-260. [01:37:11] Minnesota Coronary Experiment (MCE): Analysis of recovered data: Ramsden, Christopher E., et al. "Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73)." bmj 353 (2016): i1246. [01:39:44] Why Most Published Research Findings Are False: Ioannidis, John PA. "Why most published research findings are false." PLoS medicine 2.8 (2005): e124. [01:39:55] Richard Horton, editor of the Lancet: half of what is published is not true: Horton, Richard. "Offline: What is medicine’s 5 sigma." Lancet 385.9976 (2015): 1380. [01:41:11] The problem with reproducibility; a database of clinical trials that cannot be challenged or reproduced. [01:42:37] Editors of prominent journals losing faith in published research: Marci Angell, Richard Smith [01:44:55] Parachute study: Yeh, Robert W., et al. "Parachute use to prevent death and major trauma when jumping from aircraft: randomized controlled trial." bmj 363 (2018): k5094. [01:46:01] Benefits that are major are obvious; no randomized clinical trial necessary. [01:48:33] Preventing vs. screening. [01:51:42] Podcast: Movement Analysis and Breathing Strategies for Pain Relief and Improved Performance with physical therapist Zac Cupples. [01:51:59] Analysis of women who died in various ways, examining breast tissue; found that a high % of women had what you could diagnose as breast cancer. Study: Bhathal, P. S., et al. "Frequency of benign and malignant breast lesions in 207 consecutive autopsies in Australian women." British journal of cancer 51.2 (1985): 271. [01:53:34] Screening programs not associated with reduced CVD or death; Study: Krogsbøll, Lasse T., et al. "General health checks in adults for reducing morbidity and mortality from disease: Cochrane systematic review and meta-analysis." Bmj 345 (2012): e7191. [01:54:26] Coronary Artery Calcium (CAC) scan. Podcast: Coronary Artery Calcium (CAC): A Direct Measure of Cardiovascular Disease Risk, with Ivor Cummins. [01:54:46] Cardiologist Bernard Lown. [01:58:38] People who had measles/mumps less likely to get CVD; Study: Kubota, Yasuhiko, et al. "Association of measles and mumps with cardiovascular disease: The Japan Collaborative Cohort (JACC) study." Atherosclerosis 241.2 (2015): 682-686. [02:00:55] Life expectancy in US and UK is now falling. [02:06:46] Physical health doesn't exist without social health and psychological health. [02:07:40] Negative Twitter messages correlate with rates of heart disease; Study: Eichstaedt, Johannes C., et al. "Psychological language on Twitter predicts county-level heart disease mortality." Psychological science 26.2 (2015): 159-169. [02:09:58] People who take statins believe they’re protected so they stop exercising. Study: Lee, David SH, et al. "Statins and physical activity in older men: the osteoporotic fractures in men study." JAMA internal medicine 174.8 (2014): 1263-1270. [02:11:45] Simple changes: make friends, have good relationships, speak to your kids, exercise, eat natural food, sunshine. [02:16:53] Blood sugar measurements following funny lecture vs. boring lecture; Study: Hayashi, Keiko, et al. "Laughter lowered the increase in postprandial blood glucose." Diabetes care 26.5 (2003): 1651-1652. [02:18:08] Dr. Malcolm Kendrick’s blog.
Bruce Damer, PhD, is coauthor with David Deamer, of a new theory on the origins of life that was featured in a Scientific American cover story in 2017. His professional interests also include space exploration, virtual reality, and entheogens. He is author of Avatars: Exploring and Building Virtual Worlds on the Internet. He begins this … Continue reading "The Origin and Destiny of Life with Bruce Damer"
Dr. Bruce Damer, scientist, designer, author, as well as founder and CEO of DigitalSpace (digitalspace.com), provides a thorough overview and analysis of the origin of life as well as his vast experimentation in the area of physics-based simulations for space research. Dr. Damer is a distinguished computer scientist and active associate researcher in the Department of Biomolecular Engineering at the University of California at Santa Cruz. Dr. Damer's work with Prof. David Deamer led to the publishing of “Coupled Phases and Combinatorial Selection in Fluctuating Hydrothermal Pools: A Scenario to Guide Experimental Approaches to the Origin of Cellular Life” and, an article in the journal, Life, “A Field Trip to the Archaean in Search of Darwin's Warm Little Pond.” Their collaborative research, work, and publishing has created a surge of new interest in the subject of life's origin and kept the scientific community buzzing. Dr. Damer talks about the origin of life and his theories. He discusses Darwin's “warm little pond” theory, which Dr. Damer and Prof. Deamer have updated. As he explains, when you have a situation in which warm water is filling up an area, then draining, in a cyclical way, this creates an opportunity for life, an opportunity to make all sorts of biopolymers in a primordial soup as he refers to it. He discusses his research and experimentation that was able to create RNA, which is a necessary polymer of life. Dr. Damer's company, DigitalSpace is an innovative international corporation with a focus on the creation of virtual worlds for industrial design engineering, education as well as public outreach. In fact, it was DigitalSpace that produced notable first rounds of internet-based 3D avatar applications. From virtual events and tradeshows to advanced learning spaces for K-12 and college, complex corporate information sharing spaces for efficiency, and of course virtual worlds for artists, DigitalSpace is innovating in multiple industries. The science expert states that the barriers to creating lifeforms in a lab are time and the amount of experiments that would be necessary. He theorizes that life often tried to start then failed over historical time periods. He details random selection and mutation, and the power of a network. He describes in detail the network effect, and elaborates on progenotes, which are the last universal common ancestors, also called the last universal ancestor. Thus, as he theorizes our common ancestor was actually a network. Dr. Damer recounts many and various experiments that he has been involved with in regard to life and its origin. He provides a detailed overview of experimentation that has occurred regarding 3D modeling and physics-based simulations for a wide range of space missions, and he talks about their upcoming work with cubesats, which are miniaturized satellites for space research. Since the beginning of the 21st century, DigitalSpace has been an important player in key contracts with Adobe, NASA and other federal agencies, as well as prime contractors to produce a myriad of advanced virtual environments for space mission design and training, and so much more.
Dave and I like to talk. And we did. Here we are talking about Nietzsche, and Dr Who.
Here I talked with my friend Dr David Deamer about French Philosopher Gilles Deleuze. Dave explains to me what Deleuze was about, and then we go on to talk about how Deleuze is important for understanding cinema, and what Deleuze teach us about film, or what film can do for philosophy. Dave is the author of Deleuze, Japanese Cinema, and the Atom Bomb: The Spectre of Impossibility [Bloombsury, 2014], as well as Deleuze's Cinema Books: Three Introductions to the Taxonomy of Images [Edinburgh, 2016]. You can find out more about Dave here.
In the final paper of our Cormac McCarthy workshop, Will Large, of the University of Gloucestershire and former BSP President, gives a critique of Cormac McCarthy’s Kekulé Problem for its reliance on scientific methodology. The chair is Dr David Deamer.
In this episode we talk to the brilliant Dr. Bruce Damer. Dr. Damer is an associate researcher in the Department of Biomolecular Engineering, University of California at Santa Cruz where he collaborated with Prof. David Deamer to develop the Coupled Phases model for the origin of life. From 1999 to 2009 Dr. Damer's company, DigitalSpace Corporation, was awarded contracts by NASA to build an open source 3D modeling platform for the simulation and design of space missions. He has recently completed a 30-year effort to design a concept spacecraft capable of harvesting resources from asteroids. In the late 1990s, Dr. Damer met the American philosopher and storyteller Terence McKenna and formed a collaboration investigating the connection between computer virtual worlds and the inner worlds experienced through alternative states of consciousness. Dr. Damer's design portfolio ranges from early software user interfaces, avatar virtual world for learning and events, spacecraft concepts, and chemical models for the origin of life. At the end of the program we present "Fire in the Sky" a spoken word piece performed by Dr. Damer and set to music by DJ DISSOLV. The piece was performed on the Temple Stage at the Lightning in a Bottle Festival near Bradley CA with artist Android Jones projecting live art.
Dr. Bruce presents a second TEDx talk about his most deeply held idea: a new model for the origin of life on Earth. Developed with Dr. David Deamer, this model may help us rethink where we humans came from and where we may be going.
Dr. Bruce presents a second TEDx talk about his most deeply held idea: a new model for the origin of life on Earth. Developed with Dr. David Deamer, this model may help us rethink where we humans came from and where we may be going.
Heron picked up his artwork. Welcome Salon-ers! No Noble Ape gene unfortunately. Model Rail Radio 100 is extensively discussed. Tom wanders through a variety of topics hinging on what your body is worth, where privacy exists in this spectrum and if at all in the future. Tom attended a talk by Bruce Damer and David Deamer http://youtu.be/nk_R55O24t4 They explore maliciousness versus unconsciousness. Tom is pleased to have shared his library with a listener. Filming the neighborhood still holds some interest to Tom. What about granularity is like joining the military?
Heron picked up his artwork. Welcome Salon-ers! No Noble Ape gene unfortunately. Model Rail Radio 100 is extensively discussed. Tom wanders through a variety of topics hinging on what your body is worth, where privacy exists in this spectrum and if at all in the future. Tom attended a talk by Bruce Damer and David Deamer http://youtu.be/nk_R55O24t4 They explore maliciousness versus unconsciousness. Tom is pleased to have shared his library with a listener. Filming the neighborhood still holds some interest to Tom. What about granularity is like joining the military?
How life may have begun on Earth, with a little help from outer space. I talk to biochemist and astrobiologist Dave Deamer about the hypothetical origins of life. Also, attempts to conjure life in the lab, and music from DNA.
It's alive! Biochemist and astrobiologist David Deamer describes how life may have begun on Earth, perhaps with a little help from outer space.