Podcasts about quiescence

Quiescence. Recorremos la geografía y sus músicas. Todos los podcast aquí: https://slumdar2.wordpress.com/musica-sin-usura/ CANAL MÚSICA SIN USURA: https://play.vargasdelmoral.com/share/s2o22255jk#/ TIMELINE AND TRACK LIST [00:01:05] – 01. ginkgo garden - secret call. [00:05:14] – 02. ani difranco - spinning room [00:07:11] – 03. divine matrix - element unknown [00:15:11] – 04. avishai cohen - quiescence [00:20:11] – 05. sleeping at last - asleep [00:26:04] – 06. jozef de schutter - celadon hill [00:29:09] – 07. ginkgo garden - blossoms from india [00:33:15] – 08. kaleo - usa today [00:37:15] – 09. divine matrix - enigmatic structure [00:45:27] – 10. avishai cohen - life and death [00:54:28] – 11. sleeping at last - bloom string [00:58:54] – 12. divine matrix - dark machine [01:08:00] – 13. sleeping at last - asleep [01:13:51] – 14. victor towle - a tear and a smile [01:18:00] – 15. siv jakobsen - lay all your love on me [01:22:20] – 16. avishai cohen - life and death - epilogue [01:25:38] – 17. ginkgo garden - one and twain

Length: 45 minutesSynopsis: This morning (1/31/24), in our unplanned Q&A, we took up four questions: (1) How do we reconcile a yearning for God to avenge the deaths of Jews with the fact that revenge is prohibited? (2a) What should a person do if they're encountering struggles in their relationship with God? (2b) In attempting to answer that question, I ended up reading almost the entirety of Footnote 4 from Halakhic Man, (3) Judaism addresses most situations in life, but what does it have to say about changing jobs? (4) Multifaceted question which I won't attempt to summarize in a sentence.-----מקורות:Mechiyas Amalek - Emulating a Vengeful Godרמב"ם - משנה תורה: ספר המדע, הלכות תלמוד תורה ז:יגרמב"ם - משנה תורה: ספר המדע, הלכות תשובה ב:בRabbi Joseph B. Soloveitchik - Halakhic Man, Footnote 4-----The Torah content for the remainder of January has been sponsored by someone who would like to remain anonymous, in honor of Hashem and all His kindness!-----If you've gained from what you've learned here, please consider contributing to my Patreon at www.patreon.com/rabbischneeweiss. Alternatively, if you would like to make a direct contribution to the "Rabbi Schneeweiss Torah Content Fund," my Venmo is @Matt-Schneeweiss, and my Zelle and PayPal are mattschneeweiss at gmail. Even a small contribution goes a long way to covering the costs of my podcasts, and will provide me with the financial freedom to produce even more Torah content for you.If you would like to sponsor a day's or a week's worth of content, or if you are interested in enlisting my services as a teacher or tutor, you can reach me at rabbischneeweiss at gmail. Thank you to my listeners for listening, thank you to my readers for reading, and thank you to my supporters for supporting my efforts to make Torah ideas available and accessible to everyone.-----Substack: rabbischneeweiss.substack.com/Patreon: patreon.com/rabbischneeweissYouTube: youtube.com/rabbischneeweissInstagram: instagram.com/rabbischneeweiss/"The Stoic Jew" Podcast: thestoicjew.buzzsprout.com"Machshavah Lab" Podcast: machshavahlab.buzzsprout.com"The Mishlei Podcast": mishlei.buzzsprout.com"Rambam Bekius" Podcast: rambambekius.buzzsprout.com"The Tefilah Podcast": tefilah.buzzsprout.comOld Blog: kolhaseridim.blogspot.com/WhatsApp Content Hub (where I post all my content and announce my public classes): https://chat.whatsapp.com/GEB1EPIAarsELfHWuI2k0HAmazon Wishlist: amazon.com/hz/wishlist/ls/Y72CSP86S24W?ref_=wl_sharel

STARFIELD ASTROCYTE AND THE TRANSWARP KEY Out of the shadow of night, out of Quiescence a light has dawned…Starchild out of the CRSLX! When we trivialize what appears insignificant which appears meaningless we shortcut the significant Making a big deal THESIS Adult neurogenesis depends on the decision of neural stem cells to leave quiescence and become neurons. In this issue, Asrican et al. show that the neuropeptide cholecystokinin released by interneurons promotes the neuronal fate through astrocytic signaling. The dentate gyrus of the hippocampus contains radial-glia-like neural stem cells (rNSCs) that give rise to functional neurons throughout the entire lifespan. Host circuits continuously integrate new dentate granule cells (GCs) that impose substantial remodeling involving synapse formation and elimination, activity-dependent competition, and modifications in the balance between excitation and inhibition (Sailor et al., 2017). Neurogenesis changes the manner in which information is processed because the remodeled network may provide new solution outputs to a given input. PLASTICITY This remarkable type of plasticity was shown to influence several functions that rely on the hippocampus, including the 1. discrimination of spatial contexts associated with positive or negative rewards, 2. detection of novel features in a familiar environment, 3. resilience to stress and depression, and 4. the ability to forget old memories (Toda et al., 2019). The transformation of rNSCs into neurons is sensitive to regulatory factors that may respond to behavior, aging, or pathological conditions. Regulation may occur at the decision to leave quiescence, the rate at which progenitor cells multiply, or at later points along the pathway that ends with a fully integrated neuron. In general, an increase in physical or cognitive activity and social interaction drives neurogenesis forward, whereas isolation, stress, or aging tend to put the brakes on the process (Kempermann, 2015). All of these variables ultimately converge into different forms of local circuit activity that will impinge on the mechanisms involved in the neurogenic pathway. Neurogenesis starts with rNSCs leaving quiescence Once active, they may self-renew to replenish the population or become progenitor cells to produce neuroblasts. Why don't they leave quiescence all at once? What keeps them dormant, and what triggers their activation? There are different components in the hippocampal neurogenic niche that might act as sensors of circuit activity and deliver local cues. Neurons, glia, the vasculature, and axons from long-range projections might release neurotransmitters, modulators, or other factors that transduce information from the niche to rNSCs (Vicidomini et al., 2020). RADIAL GLIA LIKE NEURAL STEM CELLS Understanding the mechanisms underlying the transitions from dormant rNSCs to mature GCs is critical to harness neurogenesis as a strategy to enhance circuit plasticity in the senescent brain. Both physical exercise and exploration of an enriched environment boost the electrical activity in the dentate gyrus, yet only exercise increases proliferation of rNSCs

Successful businesses require continued learning and growth. However, many entrepreneurs get stuck in ineffective, outdated practices taught or influenced by previous mentors. In this episode of Profit First For Tradies, Duayne Pearce shares his journey on how he broke the mould and transformed his business by acquiring expert help and investing in continued learning. Quiescence kills potential, so it's essential to be willing to shake things up with the way you run your business, particularly on practices that are no longer working. It's also crucial to hire the right people to fill gaps, especially in areas you're not skilled in.

“Quiescence”, a state of rest. From Quiescence through Formations into Form, Decaying and dissolving back into Quiescence. Karma, life, the process we sentient minds can witness. E-books available on threefoldlotus.com http://threefoldlotus.com/home/ebooks.htm

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.08.03.551843v1?rss=1 Authors: Sun, S., Tranchina, D., Gresham, D. Abstract: Cells arrest growth and enter a quiescent state upon nutrient deprivation. However, the molecular processes by which cells respond to different starvation signals to regulate exit from the cell division cycle and initiation of quiescence remains poorly understood. To study the role of protein expression and signaling in quiescence we combined temporal profiling of the proteome and phosphoproteome using stable isotope labeling with amino acids in cell culture (SILAC) in Saccharomyces cerevisiae (budding yeast). We find that carbon and phosphorus starvation signals activate quiescence through largely distinct remodeling of the proteome and phosphoproteome. However, increased expression of mitochondrial proteins is associated with quiescence establishment in response to both starvation signals. Deletion of the putative quiescence regulator RIM15, which encodes a serine-threonine kinase, results in reduced survival of cells starved for phosphorus and nitrogen, but not carbon. However, we identified common protein phosphorylation roles for RIM15 in quiescence that are enriched for RNA metabolism and translation. We also find evidence for RIM15-mediated phosphorylation of some targets, including IGO1, prior to starvation consistent with a functional role for RIM15 in proliferative cells. Finally, our results reveal widespread catabolism of amino acids in response to nitrogen starvation, indicating widespread amino acid recycling via salvage pathways in conditions lacking environmental nitrogen. Our study defines an expanded quiescent proteome and phosphoproteome in yeast, and highlights the multiple coordinated molecular processes at the level of protein expression and phosphorylation that are required for quiescence. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.07.24.550263v1?rss=1 Authors: Yang, J., Zou, S., Qiu, Z., Lai, M., Long, Q., Chen, H., Zhang, S., Xie, X., Gong, Y., Liu, A., Li, M., Bai, X. Abstract: Quiescence (G0) maintenance and exit are crucial for tissue homeostasis and regeneration in mammals. Here, we show that methyl-CpG binding protein 2 (Mecp2) expression is cell cycle-dependent and negatively regulates quiescence exit in cultured cells and in an injury-induced liver regeneration mouse model. Specifically, acute reduction of Mecp2 is required for efficient quiescence exit, as deletion of Mecp2 accelerates, while overexpression of Mecp2 delays quiescence exit, and forced expression of Mecp2 after Mecp2 conditional knockout rescues cell cycle reentry. The E3 ligase Nedd4 mediates the ubiquitination and degradation of Mecp2, and thus facilitates quiescence exit. Genome-wide study uncovered the dual role of Mecp2 in preventing quiescence exit by transcriptionally activating metabolic genes while repressing proliferation-associated genes. Particularly, disruption of two nuclear receptors (NRs), Rara or Nr1h3, accelerates quiescence exit, mimicking the Mecp2 depletion phenotype. Our studies unravel a previously unrecognized role for Mecp2 as an essential regulator of quiescence exit and tissue regeneration. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

“Cessation”, In our practice this word signifies our effort to cease the formations that arise from Quiescence. In effect, to prevent Karma from instantiation. E-books available on threefoldlotus.com http://threefoldlotus.com/home/ebooks.htm

By Alyse Knorr

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.02.539064v1?rss=1 Authors: Laporte, D., Massoni-Laporte, A., LEfranc, C., Dompierre, J., Mauboules, D., Nsamba, E. T., Royou, A., Gal, L., Schuldiner, M., Gupta, M., Sagot, I. Abstract: Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.03.539225v1?rss=1 Authors: Calatayud-Baselga, I., Casares-Crespo, L., Franch-Ibanez, C., Guijarro-Nuez, J., Sanz, P., Mira, H. Abstract: Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.27.538084v1?rss=1 Authors: Megarioti, A. H., Athanasopoulos, A., Koulouris, D., Esch, B. M., Makridakis, M., Lygirou, V., Samiotaki, M., Zoidakis, J., Sophianopoulou, V., Andre, B., Froehlich, F., Gournas, C. Abstract: Quiescence is a common cellular state, required for stem-cell maintenance and microorganismal survival under stress conditions or starvation. However, the mechanisms promoting quiescence maintenance remain poorly known. Plasma membrane components segregate into distinct microdomains, yet the role of this compartmentalization in quiescence remains unexplored. Here, we show that Flavodoxin-like proteins (FLPs), ubiquinone reductases of the yeast eisosome membrane compartment, protect quiescent cells from lipid peroxidation and ferroptosis. Eisosomes and FLPs expand specifically in respiratory-active quiescent cells, and mutants lacking either show accelerated aging, defective quiescence maintenance, and accumulate peroxidized phospholipids with monounsaturated or polyunsaturated fatty acids (PUFA). FLPs are essential for the extra-mitochondrial regeneration of the lipophilic antioxidant ubiquinol. FLPs, alongside the Gpx1/2/3 glutathione peroxidases, prevent iron-driven, PUFA-dependent ferroptotic cell death. Our work is the first description of ferroptosis-protective mechanisms in yeast and introduces plasma membrane compartmentalization as an important factor for the long-term survival of quiescent cells. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.14.532547v1?rss=1 Authors: Fuchigami, T., Itokazu, Y., Yu, R. K. Abstract: The postnatal neural stem cell (NSC) pool hosts quiescent and activated radial glia-like NSCs contributing to neurogenesis throughout adulthood. However, the underlying regulatory mechanism during the transition from quiescent NSCs to activated NSCs in the postnatal NSC niche is not fully understood. Lipid metabolism and lipid composition play important roles in regulating NSC fate determination. Biological lipid membranes define the individual cellular shape and help maintain cellular organization and are highly heterogenous in structure and there exist diverse microdomains (also known as lipid rafts), which are enriched with sugar molecules, such as glycosphingolipids. An often overlooked but key aspect is that the functional activities of proteins and genes are highly dependent upon their molecular environments. We previously reported that ganglioside GD3 is the predominant species in NSCs and that the reduced postnatal NSC pools are observed in global GD3-synthase knockout (GD3S-KO) mouse brains. The specific roles of GD3 in determining the stage and cell-lineage determination of NSCs remain unclear, since global GD3S-KO mice cannot distinguish if GD3 regulates postnatal neurogenesis or developmental impacts. Here we show that inducible GD3 deletion in postnatal radial glia-like NSCs promotes the NSC activation, resulting in the loss of the long-term maintenance of the adult NSC pools. The reduced neurogenesis in the subventricular zone (SVZ) and the dentate gyrus (DG) of GD3S-conditional-knockout mice led to impaired olfactory and memory functions. Thus, our results provide convincing evidence that postnatal GD3 maintains the quiescent state of radial glia-like NSCs in the adult NSC niche. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.13.532403v1?rss=1 Authors: Tomasin, R., Rodrigues, A. M., Manucci, A. C., Bruni-Cardoso, A. Abstract: Cell context is key for cell phenotype. Using physiologically relevant models of laminin-rich ECM (lrECM) induction of mammary epithelial cell quiescence and differentiation, we have provided a landscape of the status of key molecular players involved in the proliferation/quiescence decision. Repression of some positive regulators of the cell cycle, such as cyclins and CDKs, occurred already at the mRNA level, whereas negative regulators of the cell cycle, such as Pten and p27, were upregulated only at the protein level. Interestingly, cell cycle arrest occurred despite the active status of Fak, Src and PI3k, because their downstream proliferative signalling pathways were repressed, suggesting the existence of a disconnecting node between upstream and downstream proliferative signalling in quiescent cells. Pten fulfils this role. Inhibition of Pten increased proliferation and restored Akt/mTORC1/2 and Mapk signalling in cells exposed to lrECM. In mice, Pten levels were positively correlated to the basement membrane thickness in the developing mammary epithelia, and Pten localized to the apicolateral membrane of luminal cells both in in ducts and near the nascent lumen in terminal end bud, characteristics consistent with a role for Pten in inducing and sustaining quiescence and tissue architecture. Accordingly, in 3D acininogenesis models, Pten was required for the onset and maintenance of quiescence, cell polarity and lumen assembly. The notion that lrECM-triggered differentiation involves a signalling circuitry with many layers of regulation provides an explanation for the resilience of quiescence within a growth-suppressive microenvironment, and that perturbations in master regulators, such as Pten, could disrupt the quiescent phenotype. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.02.530846v1?rss=1 Authors: Li, Y., Liu, C., Bai, X., Li, M., Duan, C. Abstract: The cell proliferation-quiescence decision plays fundamental roles in tissue formation and regeneration, and its dysregulation can lead to human diseases. In this study, we performed transcriptomics and genetic analyses using a zebrafish model to identify pathways and genes involved in epithelial cell quiescence-proliferation regulation. In this in vivo model, a population of GFP-labeled epithelial cells known as ionocytes were induced to reenter the cell cycle by a physiological stress. Transcriptomics analysis identified 1168 genes up-regulated and 996 genes down-regulated in the reactivated cells. GO and KEGG pathway analyses revealed that genes involved in transcription regulation, cell cycle, Foxo signaling, and Wnt signaling pathway are enriched among the up-regulated genes, while those involved in ion transport, cell adhesion, and oxidation-reduction are enriched among the down-regulated genes. Among the top up-regulated genes is FK506 binding protein 5 (Fkbp5), a member of the conserved immunophilin family. CRISPR/Cas9-mediated Fkbp5 deletion abolished ionocyte reactivation and proliferation. Pharmacological inhibition of Fkbp5 had similar effects. Further analyses showed that genetic deletion and inhibition of Fkbp5 impaired Akt signaling. Forced expression of a constitutively active form of Akt rescued the defects caused by Fkbp5 inhibition. These results uncover a previously unrecognized role of Fbkp5 in regulating the quiescence-proliferation decision via Akt signaling. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.16.520731v1?rss=1 Authors: Bartlome, S., Xiao, Y., Ross, E., Dalby, M. J., Berry, C. C. Abstract: Breast cancer is the leading cause of cancer mortality in women worldwide and commonly metastasizes to the bone marrow, drastically reducing patient prognosis and survival. In the bone marrow niche, metastatic cells can enter into a dormant state, thereby evading immune surveillance and treatment, and can be reactivated to enter a proliferative state due to poorly understood cues. Mesenchymal stromal cells (MSCs) maintain cells in this niche partly by secreting extracellular matrix and paracrine factors and by responding to regenerative cues. MSCs also produce extracellular vesicles (EVs) that carry a range of cargoes, some of which are implicated in cell signalling. Here, we investigate if the changing metabolic state of MSCs alters the cargoes they package into EVs, and how these changing cargoes act on dormant breast cancer cells (BCCs) using an in vitro BCC spheroid model and a scratch assay to create a regenerative demand on MSCs. Our findings show that EVs produced by standard MSCs contain glycolytic metabolites that maintain BCC dormancy. When MSCs are placed under a regenerative demand and increase their respiration to fuel differentiation, these metabolites disappear from the EV cargo and their absence encourages rapid growth in the BCC spheroids. This work implicates EVs in cancer cell dormancy in the bone marrow niche and indicates that pressures on the niche, such as regeneration, can be a driver of BCC activation. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Reconstructing the Assembly of Massive Galaxies II Galaxies Develop Massive and Dense Stellar Cores as They Evolve and Head Toward Quiescence at Cosmic Noon by Zhiyuan Ji et al. on Wednesday 23 November We use the SED-fitting code Prospector to reconstruct the nonparametric star formation history (SFH) of massive ($log M_*>10.3$) star-forming galaxies (SFGs) and quiescent galaxies (QGs) at redshift $z_{rm{obs}}sim2$ to investigate the joint evolution of star-formation activity and structural properties. We find significant correlations between the SFH of the galaxies and their morphology. Compared to extended SFGs, compact SFGs are more likely to have experienced multiple star-formation episodes, with the fractional mass formed during the older ($ge1$ Gyr) episode being larger, suggesting that high-redshift SFGs assembled their central regions earlier and then kept growing in central mass as they become more compact. The SFH of compact QGs does not significantly differ from the average for this category, and shows an early burst followed by a gradual decline of the star formation rate. The SFH of extended QGs, however, is similar to that of post-starburst galaxies and their morphology is also frequently disturbed. Knowledge of the SFH also enables us to empirically reconstruct the structural evolution of individual galaxies. While the progenitor effect is clearly observed and accounted for in our analysis, it alone is insufficient to explain the observed structural evolution. We show that, as they evolve from star-forming phase to quiescence, galaxies grow massive dense stellar cores. Quenching begins at the center and then propagates outward to the rest of the structure. We discuss possible physical scenarios for the observed evolution and find that our empirical constraints are in good quantitative agreement with the model predictions from dissipative accretion of gas to the center followed by massive starbursts before final quiescence (wet compaction). arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2208.04325v2

Reconstructing the Assembly of Massive Galaxies II Galaxies Develop Massive and Dense Stellar Cores as They Evolve and Head Toward Quiescence at Cosmic Noon by Zhiyuan Ji et al. on Tuesday 22 November We use the SED-fitting code Prospector to reconstruct the nonparametric star formation history (SFH) of massive ($log M_*>10.3$) star-forming galaxies (SFGs) and quiescent galaxies (QGs) at redshift $z_{rm{obs}}sim2$ to investigate the joint evolution of star-formation activity and structural properties. We find significant correlations between the SFH of the galaxies and their morphology. Compared to extended SFGs, compact SFGs are more likely to have experienced multiple star-formation episodes, with the fractional mass formed during the older ($ge1$ Gyr) episode being larger, suggesting that high-redshift SFGs assembled their central regions earlier and then kept growing in central mass as they become more compact. The SFH of compact QGs does not significantly differ from the average for this category, and shows an early burst followed by a gradual decline of the star formation rate. The SFH of extended QGs, however, is similar to that of post-starburst galaxies and their morphology is also frequently disturbed. Knowledge of the SFH also enables us to empirically reconstruct the structural evolution of individual galaxies. While the progenitor effect is clearly observed and accounted for in our analysis, it alone is insufficient to explain the observed structural evolution. We show that, as they evolve from star-forming phase to quiescence, galaxies grow massive dense stellar cores. Quenching begins at the center and then propagates outward to the rest of the structure. We discuss possible physical scenarios for the observed evolution and find that our empirical constraints are in good quantitative agreement with the model predictions from dissipative accretion of gas to the center followed by massive starbursts before final quiescence (wet compaction). arXiv: http://arxiv.org/abs/http://arxiv.org/abs/2208.04325v2

Listen to a blog summary of a trending research paper published by Oncotarget on July 28, 2022, entitled, "Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast." ______________________________________ The mechanisms of cellular aging and cellular quiescence have been preserved throughout evolution. Cellular quiescence is a temporary state of cell cycle arrest and low metabolic activity. Importantly, quiescent (Q) cells maintain the ability to quickly activate and re-enter the cell cycle (in response to the appropriate stimuli). Recent research has shown that cellular quiescence may play a role in cellular aging. In a 2020 study, research findings indicated that the rate at which yeast cells age is determined by a complicated program that affects 1) when a state of quiescence is entered, 2) how long quiescence is maintained and 3) when the cell exits quiescence. Researchers found that caloric restriction (CR) (a geroprotective intervention) appears to remodel this program, and this remodeling could be responsible for the CR-dependent delay of yeast chronological aging. Thus, the researchers considered the question: Does a single mechanism exist which links cellular aging to cellular quiescence? “We have introduced a new yeast model for studying mechanisms linking cellular aging to cellular quiescence [109, 110].” In a new study, researchers (Anna Leonov, Rachel Feldman, Amanda Piano, Anthony Arlia-Ciommo, Jennifer Anne Baratang Junio, Emmanuel Orfanos, Tala Tafakori, Vicky Lutchman, Karamat Mohammad, Sarah Elsaser, Sandra Orfali, Harshvardhan Rajen, and Vladimir I. Titorenko) from Concordia University, Montreal, used a new yeast model to test their hypothesis that a mechanism exists linking cellular aging to cellular quiescence. On July 28, 2022, their research paper was published in Oncotarget and entitled, “Diverse geroprotectors differently affect a mechanism linking cellular aging to cellular quiescence in budding yeast.” Full blog - https://www.oncotarget.org/2022/08/05/does-a-mechanism-linking-cellular-aging-to-cellular-quiescence-exist/ DOI - https://doi.org/10.18632/oncotarget.28256 Correspondence to - Vladimir I. Titorenko - vladimir.titorenko@concordia.ca Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28256 Keywords - cellular aging, cellular quiescence, longevity, gerotargets, geroprotectors About Oncotarget Oncotarget is a peer-reviewed, open access biomedical journal covering research on all aspects of oncology. To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: SoundCloud - https://soundcloud.com/oncotarget Facebook - https://www.facebook.com/Oncotarget/ Twitter - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/OncotargetYouTube LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Media Contact MEDIA@IMPACTJOURNALS.COM 18009220957

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Ramana Maharshi's words: "If in this manner the mind becomes absorbed in the Heart, the ego or “I”. Which is the center of the multitude of thoughts and pure Consciousness or Self, which subsists during all the states of the mind, alone remains resplendent. It is this state where there is not the slightest trace of the “I”-thought, that is the true Being of oneself. And that is called Quiescence or Mouna (Silence)." Commentary by Richard Clarke, with an audio by Nome, and a short guided Self-inquiry. 

A State of Quiescence + 2 Others 安穩之處 + 其他兩首 --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

Where to even begin? Dr. Greta Bowling joins the podcast for Episode 24, which is action-packed from start to finish. It is our longest episode to date that you won't want to miss a second of. It is chalk full of knowledges, tangents (Is Ryan Gosling Hot or Not?), poems, corrections, rants, Freudian slips, and flat-out derailments. Some NewNews quick hits: the naked mole rat strikes again seizing the moment, we learn about the weird feeding habits of the cone snail, and the Amazon Rain Forest is no longer a net carbon sink. The episode begins by diving deep into all things coral reefs. We start our discussion with the geologic setting of coral reefs and then segue into biological realm of reefs. We talk about the diversity of coral environments, some of the more famous reefs, some key characteristics they exhibit, and describe various coral organisms along with their symbiotic pals. Between the bars, we present to you another Mineral Minute that was sponsored by the potassic-magnesio fluoro sodium amphibole, Fluoroarfvedsonite. We wrap up the back half with talks of natural factors, such as ENSO and predation, and anthropogenic factors, such as overfishing, plastics, acidification, and warming ocean temperatures) endangering fragile ecosystems. There is some debate about Silica versus Carbon regarding coral evolution, HotDog stands are used as a Coral Metaphor, and reefs may create their own sunscreen. Say what?! We close things out with some of our least favorite music genres, and Bryan may or may not lose his cool during this week's That Freaking Rocks. Some of our favorite words include: Quiescence: in a state or period of inactivity or dormancy Defervescence: the abatement of a fever as indicated by a decrease in bodily temperature Anticlinorium: is a large anticline on which minor folds are superimposed Boudinage: a geological term for structures formed by extension, where a rigid, tabular body such as hornfels is stretched and deformed amidst less competent surroundings Cellar Door: no meaning in this context Heliodor: golden beryl; a variety that receives its yellow color from Fe 3+ ions Ineffable: too great or extreme to be expressed or described in words Ephemeral: lasting for a very short time Cromulent: Used to describe a dubious or made-up word, term, or phrase that is entirely plausible because it makes logical sense within existing language conventions Mellifluous: sweetly or smoothly flowing; sweet-sounding Remember to Be Cool, Stay Tuned, and Keep It On The Rocks! --- Support this podcast: https://anchor.fm/geology-on-the-rocks/support

It's been a year since the first episode came out! And do we have something special planned? You bet we don't as our release schedule was pushed back. Anyway, here's the second half of the battle with the Church of Quiescence's flesh golem.Artwork by Florence Scott Music by Sam WheatleyAdditional Music by Gaby IrvingEdited by Calvin Lowe The Dungeon Masters are Calvin Lowe and Alastair Fleming The Players are Smo Ariyella, Thomas Toth, Ben VT and Sam Wheatley Support the show (https://www.patreon.com/calvinlowefiction)

Dr. Tom Cheung is the S H Ho Associate Professor of Life Science at the Hong Kong University of Science and Technology. His lab investigates the molecular pathways that control muscle stem cell quiescence and stem cell-mediated tissue regeneration.

Alyse Knorr writes about motherhood and loss. Produced by Katie Klocksin.

In this episode of the “Essential Oils & Herbal Apothecary” we cover roman chamomile essential oil. Long known for its relaxing effects… The post #38: The Quiescence of Roman Chamomile Essential Oil appeared first on Naturopathic Earth.

Quiescence is the state of when a cell is resting and at peace. We certainly felt at ease in this week’s episode. We’re joined by the beautiful and passionate, Annalise Drok, our very first guest! Annalise has focused on developing her knowledge and understanding of women’s health and fertility. She’s been awarded a Bachelor of Applied Sciences in Chinese Medicine and a Bachelor of Consumer and Applied Sciences in Human Nutrition. Her calm and patient nature was well demonstrated as the three co-hosts (Nic, Charlene, and Tim/Tom) tried to pick her brains for life after a student. You can catch her at:  Instagram: quiescencechinesemed FaceBook: Quiescence Chinese Medicine       Find us on FaceBook! https://www.facebook.com/ForeverYangPodcast/ Find us on Instagram! Nic - acu.nicholas Charlene - charlene.tcm Brendan - b.drill_ For any business enquiries please contact: foreveryang.podcast@gmail.com

On this week's podcast, Jessie Moritz discusses her research on the Rentier States. Moritz is a Postdoctoral Research Associate at the Institute for the Transregional Study of the Contemporary Middle East, Central Asia, and North Africa, Princeton University. She has conducted interviews with over 150 citizens of Qatar, Bahrain, Oman, and Saudi Arabia, including members of royal families, ministers, elected and appointed representatives, development experts, entrepreneurs, prominent leaders in civil society, and youth activists involved in protests since 2011. Her current research focuses on the political economy of oil in the Arabian Peninsula, with a particular focus on post-2014 economic reform programs and their impact on state-society relations. We have to understand that before we get to oil and gas and democratization, we have to understand oil and gas and lack of mobilization- whether that's through the absence of taxation or whether that's through cooptation or the funding of a repressive apparatus. Whatever cause or mechanism we think is the most important, we have to understand the oil societal quiescence link first, and then we can move on to 'will it overthrow a authoritarian regime?'. And then 'will the outcome of that regime ever be democracy?'. There's so many steps in that process.

This week on Minor Inconvenience, I discuss "Fuck Growing Up" by Common Grounds, "Quiescence" by Thought Patterns, and "Blank Daze" by Mr. Doubtfire.Email me! @ MinorInconveniencePodcast@gmail.com

BleedTV covers the Series Finale / final episode 110 of The Bastard Executioner called "Blood and Quiescence". With a heavy heart, Zac discusses the episode and the season as a whole.Send us your comments and feedback to bleedtvpodcast@gmail.com , @bleedtvpodcast on twitter, and or our Facebook page.

Augmented Album. Composed & performed © Gary Hayes except 19 Oldfield. Recorded in grabbed moments 2008. Gary plays: Steinway Grand, Music Tech, Keyboards, Martin Steel & Classical Guitars, Salvi & Custom String Harps, Vocals. Logic, Reason, Live, Macs

Ed Horwich talks to photographic partnership Steve McCoy and Stephanie Wynne, about their recent exhibition Quiescence and how they manage to merge personal projects with their full time commercial work. www.mccoywynne.co.uk edphoto.com shotupnorth.co.uk The SUN Awards recognises and rewards the best commercial photography in the UK regions, working in the disciplines of Advertising, Design, Fashion or Editorial