Podcasts about footnote

Four times, the first three being in today's reading of the 9th chapter of Isaiah, the prophet states God's attitude is that, “For all this his anger is not turned away and his hand is stretched out still” [v.12,17, 21 In their own strength they think they can ignore God and restore the things that have gone wrong, to bounce back from a disaster and rebuild saying, “the bricks that have fallen, but we will build with dressed stones; the sycamore have been cut down, but we will put cedars in their place” [v.10].The nation refused to see that it was the LORD who had caused these disasters, but their thoughts were on rebuild, to make things better than they had been; they did not see that it was evidence of God's anger and further punishment would come for “the people did not turn to him who struck them, nor inquire of the LORD of hosts.”[v.13] As a result the LORD was going to have “no compassion (even) on their fatherless and widows; for everyone is godless and an evildoer, and every mouth speaks folly (Footnote: ‘disgraceful things')” [v.17].There is a solemn lesson in this for today; disasters continue to multiply in different parts of the world, extreme weather events, earthquakes and pestilence are multiplying. As we read on Isaiah we will come to several prophetic visions, for example on Thursday we will read, “ I will punish the world for its evil, and the wicked for their iniquity; I will put an end to the pomp of the arrogant, and lay low the pompous pride of the ruthless. I will make people more rare than fine gold, and mankind than the gold of Ophir. Therefore I will make the heavens tremble, and the earth will be shaken out of its place, at the wrath of the LORD of hosts in the day of his fierce anger.” (Ch. 13 v11-13) . .But for those who looking for light in the darkness, what marvellous light is to be found in today's chapter! Verses 7 & 8 tell us “For unto us a child is born … and the government shall be on his shoulder … of the increase of his government and peace there will be no end … to establish it and to uphold it with justice and with righteousness from this time forth and forevermore. The zeal of the LORD of hosts will do this.” “From this time forth”?From the time Jesus returns! Yesterday we ended by quoting today's Thessalonians chapter (5 v.23,24) – look at it again! May we all have a clear vision of the light in the darkness,, “for all this” folly of godlessness we see today our world will one day – soon – feel the fullness of the Creator's anger. Let us make our vision of the light as clear as we can.

Every so often we're going to bring you something we've been calling off-cuts and footnotes. These are extended scenes and deep dives that didn't make the final cut of the main episodes. This is also a place where we can talk about your questions and comments. So feel free to send your thoughts to htbdpodcast@gmail.com in a voice note or a quick message. This episode is a footnote. We're going to take a deeper dive into housing in the context of the Soviet Union. In the USSR and generally in the post-World War II city planning regimes, housing and new construction technologies played a major role in urban development booms. We're still feeling the impact of it to this day. The Soviet Union is a major contributor to this moment because it planned standardized residential developments to be deployed around its territories and spheres of influence. These designs were replicated so extensively that you can find them all over the world, from Poland to Iran from Estonia to Vietnam and of course in Odes[s]a. In this footnote, we'll hear from Kate Malaia, the author of Taking the Soviet Union Apart Room by Room, about the development of these residential blocks. We'll also hear from Odesiti who lived in the Soviet Union's first housing experiment, the communalki or communal apartments and later transitioned to different types of residential housing in Soviet Odes[s]a.

Fresh from last week's discussion of Mickey Mouse, Chris and Alex are once again joined by Dr David McGowan (Lecturer in the Contextual and Theoretical Studies of Animation at the University of the Arts London) to map the mythology of the Golden Age of Animation, and in particular how this phase of the medium's history has been framed in relation to the cartoon's move from silent to sound technology but also its emergent stability and security as an industrial art form. Listen as they cover animation's artistic recognition, questions of distribution, and the economic dominance of the major players in Hollywood cartoon production; the precise terms of ‘golden' as a descriptor for the business of U.S. commercial animation, but also how alternate histories and representations suggest its limits for certain studios and identities; technological innovation, Disney-level aesthetic qualities, and the solidification of ‘full animation'; and the sentimentality afforded to the Golden Age as a period defined as much by dead ends as the heralding of animation's growing prestige and ambition.

Chris and Alex take a look at animation's historical and troubling relationship to race with this examination of the Censored Eleven, a collection of controversial Looney Tunes and Merrie Melodies cartoons produced during the 1930s and 1940s removed from syndication since 1968 for their inclusion of harmful and offensive racist stereotypes. Topics include histories of animating the other, identity, and experience within the medium and legacies of minstrelsy performance; the visibility of Black culture and jazz-based parodies like Bob Clampett's Coal Black and de Sebben Dwarfs (1943) against more hidden (and no less damaging) iconographies within cartoon representation; and what it means to confront such legacies of racism within the critical study of animation, and if erasing any and all mention of the Censored Eleven pretends that racism in Hollywood did not exist. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

In this bonus Footnote episode, Saba Sams joins us to talk about her debut novel, GUNK, which she's launching at the Brighton Festival in conversation with Fee Mac. Get tickets here. Jules has been divorced from her ex-husband Leon for five years, but she still works alongside him at the nightclub. With the arrival of Nim, a new employee at the bar, Jules is jolted awake for the first time in years and with an unexpected pregnancy in the mix, this novel poses questions around who we choose to build our families with.  Selected for Granta's Best of Young British Novelists in 2023 and author of the dazzling collection of short stories, Send Nudes, Saba Sams is a voice not to be missed. 

Episode 270 - Footnote RapFirst lookout for #OFFTHEDOME . What song is saved by a guest feature? What edited version of a song is better than the explicit version?Topics Discussed -Billboard Top 25 Female Emcees-What album should an artist have stopped after? -Fantastic Four Trailer Reaction-Which Comic Book Movie Has to Go -And MoreNO OS SONG OF THE WEEKPlease Enjoy on All Major Platforms and OverSatThePod.Com. Please Comment, Rate , and Subscribe.

Episode 270 - Footnote RapFirst lookout for #OFFTHEDOME . What song is saved by a guest feature? What edited version of a song is better than the explicit version?Topics Discussed -Billboard Top 25 Female Emcees-What album should an artist have stopped after? -Fantastic Four Trailer Reaction-Which Comic Book Movie Has to Go -And MoreNO OS SONG OF THE WEEKPlease Enjoy on All Major Platforms and OverSatThePod.Com. Please Comment, Rate , and Subscribe.

The Fantasy/Animation Footnotes complete their unofficial ‘psychoanalysis trilogy' with this look at object relations and a branch of psychoanalytic approaches to film that emerged as a competing way of thinking about cinema linked to the development of the conscious minds of children. Listen as Alex takes Chris through the contributions of the British Psychoanalytical Society and the influential work of Melanie Klein and D. W. Winnicott; the value of unconscious fantasies, creativity, and what it means to theorise play; cinema as a potentially “transitional” (and cultural) object that we can use to fantasise with; using object relations theory to think about what kind of object a film might be, and the specificity of fantasy filmmaking as ‘extra transitional'; and what a focus on objects says about how children can and do formulate relationships to the world. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

Most people don't achieve their goals (92% footnote 1). Perhaps it's because they don't set them at all. I've heard that most people don't set goals (perhaps as high as 80%) and that even fewer write them down (I've heard from 3-10%).In my experience, the big disconnect between what people want to achieve and actually achieving it centers around the fact that people haven't learned how to think strategically about the steps required to work towards their goals.In this 100th episode (!) of my podcast, we address this issue with examples to help you understand how you might break a goal down into its parts.Part 3: My friend Christine shares her thoughts on the first two parts and then we talk about her goal to raise resilient children. I love this goal not only because it's very relatable, but also because of it's "ephemeral" nature. I give her some ideas on how to make it more concrete and easier to implement on a daily basis.Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our books: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TinyURL.com/BYWDbooks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our life-design course: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.mailerpage.com/hpop⁠⁠Footnote 1. https://pubmed.ncbi.nlm.nih.gov/2980864/

Most people don't achieve their goals (92% footnote 1). Perhaps it's because they don't set them at all. I've heard that most people don't set goals (perhaps as high as 80%) and that even fewer write them down (I've heard from 3-10%).In my experience, the big disconnect between what people want to achieve and actually achieving it centers around the fact that people haven't learned how to think strategically about the steps required to work towards their goals.In this 100th episode (!) of my podcast, we address this issue with examples to help you understand how you might break a goal down into its many parts.Part 1: I share with Natascha a goal I've been working towards for the last 2.5 years: the desire to produce a stand-up comedy show. I break it down into its components. Then Natascha and I strategize around a goal she has (that I'm sure many of you can relate to): making more money.Part 2: I coach my friend Angela on her goal to improve her health with specific attention on getting better sleep because it's so foundational towards this goal.Part 3: My friend Christine shares her thoughts on the first two parts and then we talk about her goal to raise resilient children. I love this goal not only because it's very relatable, but also because of it's "ephemeral" nature. I give her some ideas on how to make it more concrete and easier to implement on a daily basis.Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our books: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TinyURL.com/BYWDbooks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our life-design course: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.mailerpage.com/hpop⁠⁠Footnote 1. https://pubmed.ncbi.nlm.nih.gov/2980864/

Most people don't achieve their goals (92% footnote 1). Perhaps it's because they don't set them at all. I've heard that most people don't set goals (perhaps as high as 80%) and that even fewer write them down (I've heard from 3-10%).In my experience, the big disconnect between what people want to achieve and actually achieving it centers around the fact that people haven't learned how to think strategically about the steps required to work towards their goals.In this 100th episode (!) of my podcast, we address this issue with examples to help you understand how you might break a goal down into its many parts.Part 1: I share with Natascha a goal I've been working towards for the last 2.5 years: the desire to produce a stand-up comedy show. I break it down into its components. Then Natascha and I strategize around a goal she has (that I'm sure many of you can relate to): making more money.Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our books: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TinyURL.com/BYWDbooks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our life-design course: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.mailerpage.com/hpop⁠⁠Footnote 1. https://pubmed.ncbi.nlm.nih.gov/2980864/

Most people don't achieve their goals (92% footnote 1). Perhaps it's because they don't set them at all. I've heard that most people don't set goals (perhaps as high as 80%) and that even fewer write them down (I've heard from 3-10%).In my experience, the big disconnect between what people want to achieve and actually achieving it centers around the fact that people haven't learned how to think strategically about the steps required to work towards their goals.In this 100th episode (!) of my podcast, we address this issue with examples to help you understand how you might break a goal down into its many parts.Part 2: I coach my friend Angela on her goal to improve her health with specific attention on getting better sleep because it's so foundational towards this goal.Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our books: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TinyURL.com/BYWDbooks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our life-design course: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.mailerpage.com/hpop⁠⁠Footnote 1. https://pubmed.ncbi.nlm.nih.gov/2980864/

Most people don't achieve their goals (92% footnote 1). Perhaps it's because they don't set them at all. I've heard that most people don't set goals (perhaps as high as 80%) and that even fewer write them down (I've heard from 3-10%).In my experience, the big disconnect between what people want to achieve and actually achieving it centers around the fact that people haven't learned how to think strategically about the steps required to work towards their goals.In this 100th episode (!) of my podcast, we address this issue with examples to help you understand how you might break a goal down into its many parts.Part 1: I share with Natascha a goal I've been working towards for the last 2.5 years: the desire to produce a stand-up comedy show. I break it down into its components. Then Natascha and I strategize around a goal she has (that I'm sure many of you can relate to): making more money.Part 2: I coach my friend Angela on her goal to improve her health with specific attention on getting better sleep because it's so foundational towards this goal.Part 3: My friend Christine shares her thoughts on the first two parts and then we talk about her goal to raise resilient children. I love this goal not only because it's very relatable, but also because of it's "ephemeral" nature. I give her some ideas on how to make it more concrete and easier to implement on a daily basis.Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our books: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TinyURL.com/BYWDbooks⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our life-design course: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠BYWDreams.mailerpage.com/hpop⁠⁠Footnote 1. https://pubmed.ncbi.nlm.nih.gov/2980864/

The Fantasy/Animation Footnotes return to psychoanalysis in order to make sense of the world through gazing and gaze theory. Alex once again takes the lead in discussing Laura Mulvey's seminal work on the gaze but also how it offers just one way of thinking about the topic, drawing instead on Lacanian psychoanalysis to distinguish between the qualities of looking and gazing. Topics include the conscious and unconscious processes involved in Lacan's ‘mirror stage'; the politics of cinema and the illusion of mastery; how the gaze both affirms identity through our engagement with the cinematic object and emerges as something not that we have but that we react to; and how ‘gazing' represents a way of seeing the world through the paradigm of consciousness, concepts, and ideas. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

In this final episode we look back with Becky and Craig on their personal pet behaviour Odyssey and how far they have come. They share the insights they have gained and how this has helped to built their relationship. They discuss the many positives of the journey but also the challenges they met on the way. Every client is an individual and every case is a unique  learning opportunity for us as clinicians, so we share what we learned on the way too. However we leave the last word to Becky and we hope you find her words inspirational. Thank you for listening. We hope this was useful to youo. If you liked this video please help to spread the word and share it with your friends, like, subscribe and turn on notifications (click/tap on the bell by the subscribe button).Footnote for those seeking professional support: If you are in the UK and would like help with your pet's behaviour, we encourage  you to seek professional advice. A list of Certificated clinical animal behaviourists, including the presenters of this show can be found at www.ccab.uk/. You can also find further details of the Lincoln Animal Behaviour Clinic at animalbehaviourclinic.lincoln.ac.uk/.  In Europe, if you want to find a veterinary behaviourist you can find a list of Diplomates (individuals who have the highest level of training available in the field) at https://www.ecawbm.org/diplomates-list. In North America, you can find a directory of certified applied animal behaviorists at https://www.animalbehaviorsociety.org/web/committees-applied-behavior-directory.php and board certified veterinary behaviorists at: https://www.dacvb.org/search/custom.asp?id=4709.#petbehaviourodysseys, #whatmakesyouclick #PBO

Listen as Alex takes Chris through the desires and distresses of psychoanalysis in this new Fantasy/Animation Footnote, working through its status as a branch of psychological theory and the contribution of the seminal work of Sigmund Freud. Other topics in this instalment include the emergence of psychoanalytic thinking at the end of the nineteenth-century and its subsequent interdisciplinary influence; parapraxis and the interpretation, processing, and diagnosis of dreams; the ‘turn' towards psychoanalytic film theory during the 1970s via Jacques Lacan and its renewed emphasis on the unconscious and desire; and the repressed of cinema spectatorship and what this means for understanding the film apparatus as a device of ideological positioning. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

When we ask clients to do something it is important that we support them throughout the process. What a client needs at this time is not the same as what they need to encourage initial action. At this time things like reinforcement for progress, become particularly important, as do helpful relationships that support the change process.  Again this is something that is perhaps not as widely appreciated as it should be. This aspect of treatment forms the basis of the current episode. Becky and Craig discuss the highs and lows of their Odyssey. They also share with us, what it was that made them think they were making progress.  They  thus provide invaluable insight for others. What an owner sees as an important marker of success and what a clinician sees as important in this regard are not always the same initially. We must listen to our clients and help them achieve meaningful goals. If you liked this video please help to spead the word and share it with your friends, like, subscribe and turn on notifications (click/tap on the bell by the subscribe button).Footnote for those seeking professional support: If you are in the UK and would like help with your pet's behaviour, we encourage  you to seek professional advice. A list of Certificated clinical animal behaviourists, including the presenters of this show can be found at www.ccab.uk/. You can also find further details of the Lincoln Animal Behaviour Clinic at animalbehaviourclinic.lincoln.ac.uk/.  In Europe, if you want to find a veterinary behaviourist you can find a list of Diplomates (individuals who have the highest level of training available in the field) at https://www.ecawbm.org/diplomates-list. In North America, you can find a directory of certified applied animal behaviorists at https://www.animalbehaviorsociety.org/web/committees-applied-behavior-directory.php and board certified veterinary behaviorists at: https://www.dacvb.org/search/custom.asp?id=4709.#petbehaviourodysseys, #whatmakesyouclick #PBO

Nikki & Brie are refreshed, recharged, and ready for Women's History Month…despite Daylight Savings Time! The Garcia Twins have had different experiences with springing forward and losing an hour, but Brie's doing her best to get on the same page as all of the clocks in her life, even if she's not happy about it. Nikki & Brie had a quick trip down to LA to take in the red carpet premiere of the new film, Queen of the Ring, which tells the incredible story of Mildred Burke. She was a trailblazer in women's wrestling and an icon for women of any age chasing their dreams. It's a movie that inspired both Nikki and Brie and allowed them to take a moment to see the bigger picture of women's wrestling and their roles in an enduring legacy that connects them to Mildred. At the movie premiere, they also had a chance to see some old friends, including Saraya, Trish, Amy, Toni, Johnny, and Daria. It is Lent, so Brei breaks down her decision to give up TV for a few weeks and embrace one specific book for the season: Let Them by Mel Robbins. The book is changing Brie's life right now, and it's a message that she needed to hear, so expect some more developments as Lent continues. Then Nikki & Brie play a round of Fair or Foul? They look at real-life moments and decide whether some scenarios are okay or out of bounds. Spoiler Alert: They don't always agree! Then Brie closes things out with Inspiration & Affirmation, that is simple and profound in a way that it blew Nikki's mind. Call Nikki & Brie at 833-GARCIA2 and leave a voicemail! Follow Nikki & Brie on Instagram, follow the show on Instagram and TikTok and send Nikki & Brie a message on Threads! Follow Bonita Bonita on Instagram Book a reservation at the Bonita Bonita Speakeasy To watch exclusive videos of this week's episode, follow The Nikki & Brie Show on YouTube, Facebook, and TikTok! You can also catch The Nikki & Brie Show on SiriusXM Stars 109!

Individualising treatment for a given client and their pet is essential and so we have to go beyond the theoretical techniques used in human and animal behaviour modification. In the last episode we looked at the COM-B model of human behaviour change. COM-B stands for Capability, Opportunities and Motivations underpinning human Behaviour change. We also introduced the Theoretical Domains, like an individual's knowledge, beliefs about their capabilities, emotions, ability to visualize a goal and so forth and the Intervention Functions used to make these as optimal as we can for the client. In this episode we return to the dog side of things in our discussion with Becky and Craig . We talk about the importance of avoidance of triggers, and diary keeping but expand on two protocols we have developed at Lincoln. The safe haven and sensitive carer routines. These may be somewhat different to other versions of the protocol that are commonly discussed by behaviourists and trainers. It is important to pay attention to certain details if they are to work as we would hope. When choosing interventions it is important that they are right for that client and so we introduce the concept of the APEASE criteria, from the human behaviour change literature, for assessing their suitability. These are important considerations: I detail here what each letter in the acronym APEASE stands for: A is  for acceptabilityP for practicalE for effectiveA for affordableS for safeEquitable, i.e is it fairWe discuss these further  in the current episode,  and the last E  is an important ethical consideration and may be where some quick fixes fall down. Footnote for those seeking professional support: If you are in the UK and would like help with your pet's behaviour, we encourage  you to seek professional advice. A list of Certificated clinical animal behaviourists, including the presenters of this show can be found at www.ccab.uk/. You can also find further details of the Lincoln Animal Behaviour Clinic at animalbehaviourclinic.lincoln.ac.uk/.  In Europe, if you want to find a veterinary behaviourist you can find a list of Diplomates (individuals who have the highest level of training available in the field) at https://www.ecawbm.org/diplomates-list. In North America, you can find a directory of certified applied animal behaviorists at https://www.animalbehaviorsociety.org/web/committees-applied-behavior-directory.php and board certified veterinary behaviorists at: https://www.dacvb.org/search/custom.asp?id=4709.  #petbehaviourodysseys, #whatmakesyouclick #PBO

Are you struggling to live boldly for Christ in a world that often opposes your faith? Join Adam Castellano and Pastor Tony Caffee as they dive into Acts 4:1-22, exploring Peter and John's courageous stand in the face of persecution.For the study resources and manuscript go to VBVF.ORG

Fantasy/Animation turns to a kind of magic for this latest Footnote episode, and the role of the magical in the distinction that lies within fantasy between the knowingness of illusion and the pursuit of rationality. Expect turns to how magic can embody both an appreciation of a non-scientific worldview and a magic show's illusion and sleight-of-hand; theological superstition, spirituality and religion, and what this means for understanding belief in magic as a form of ‘social action'; magic as vital to thinking through the strangeness of fantasy and its language of the fantastic; and how magic invokes a pleasure of engagement rooted in choosing feeling over rationality. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

In this episode we  talk about the process of implementing treatment. In particular we discuss the less often discussed issue of human behaviour change, with a  focus on how we consider the underpinning capability, opportunities and motivation of a client to enable more effective change. We introduce the theoretical domains framework. This is a synthesis of lots of different evidence based approaches for bringing about human behaviour change. At its simplest it is a list of about 14 different ways in which  we can help people bring about change. By doign this we can more accurately set expectations for change. Find out more by listening to the episode, and please do give us a rating if you have enjoyed the episode. Footnote on seeking help: If you are in the UK and would like help with your pet's behaviour, we encourage  you to seek professional advice. A list of Certificated clinical animal behaviourists, including the presenters of this show can be found at www.ccab.uk/. You can also find further details of the Lincoln Animal Behaviour Clinic at animalbehaviourclinic.lincoln.ac.uk/.  In Europe, if you want to find a veterinary behaviourist you can find a list of Diplomates (individuals who have the highest level of training available in the field) at https://www.ecawbm.org/diplomates-list. In North America, you can find a directory of certified applied animal behaviorists at https://www.animalbehaviorsociety.org/web/committees-applied-behavior-directory.php and board certified veterinary behaviorists at: https://www.dacvb.org/search/custom.asp?id=4709. #petbehaviourodysseys, #whatmakesyouclick #PBO

In this latest Fantasy/Animation Footnote, Chris and Alex wonder about wonder - a term that emphatically traverses both fantasy and animation as fields of study, yet with alternate meanings and connotations related to everything from mid-1990s cultures of special effects appreciation to fantasy's historical links to the so-called “wonder film.” Topics include the “wonder years” of special effects production and reception during the 1990s via what Michele Pierson calls a growing “connoisseurship” of effects technologies; histories of the effects-laden ‘wonder film' as an industrial category and links to the ‘wonder tale'; wonder itself as both the aestheticization of thought and/or thought induced by aesthetics; wonder's role in fantasy scholarship to describe distinctions between fantasy, horror, and science-fiction; and more recent turns towards expanded animation and the spectatorship and ‘siting' of wonder in the digital age. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

Teaching and Study helps for the Doctrine and Covenants 12-17, Joseph Smith-History 1:66-75 lesson in the Come Follow Me manual. This podcast will give you ideas and insights on how to teach Christ and Scripture Centered gospel lessons with more relevancy and power. These insights coincide with the lesson for February 17-February 23 in the Come Follow Me manual. Principles include: The Priesthood is Restored, THE Footnote, Faith First, and more.Link to purchase fake police badge and sunglasses: https://amzn.to/3Q2yTE3Link to purchase Sticky Notes: https://amzn.to/3EnbZodLink to "Days of Harmony" Video: https://www.churchofjesuschrist.org/media/video/2018-03-1000-days-of-harmony?lang=eng Link to "Nearer My God to Thee" Video: Nearer, My God, To Thee - Music VideoLink to "A Day for the Eternities" Video: https://www.churchofjesuschrist.org/media/video/2018-03-2000-a-day-for-the-eternities?lang=eng To purchase the Doctrine and Covenants Bundle Subscription, click here:  https://www.etsy.com/shop/TeachingWithPowerYou can reach me by email at teachingwithpower@gmail.com Music Provided by Youtube Audio Library. Track Name: Dancing Star. https://teachingwithpower.wixsite.com/teachingwithpower IMAGES USED:DALL-E AI images have been used in the production of some of the illustrations used in this video. Story Illustration pictures from Bible illustrations provided by Sweet Publishing, http://sweetpublishing.com, and issued under Creative Commons 3.0 Share Alike Unported License.All other pictures are listed in the Public DomainDisclaimer: I alone am responsible for the content of these videos. The opinions in them are mine. They represent my ideas and insights and do not reflect the official position of The Church of Jesus Christ of Latter-day Saints.

Episode 1: Welcoming a dog into your life – the Odyssey beginsIn this episode we introduce you to Becky, Craig and Drax. We find out how Drax came into Becky's and Craig's life, including the emotional background that so often underpins the decision to acquire a pet. We discuss their love and joy with Drax during these early days in their home, before they felt that things were not turning out quite how they had expected and hoped. Their love and commitment persisted, but the joy became tinged with sadness and frustration as they started to feel there was a problem that was seriously impacting  their quality of life. This led them to navigating  the unfamilar and unchartered territory of training and behaviour, as they tried to  get professional advice and support. Who should they turn to for help? Footnote for those seeking professional support: If you are in the UK and would like help with your pet's behaviour, we encourage  you to seek professional advice. A list of Certificated clinical animal behaviourists, including the presenters of this show can be found at www.ccab.uk/. You can also find further details of the Lincoln Animal Behaviour Clinic at animalbehaviourclinic.lincoln.ac.uk/.  In Europe, if you want to find a veterinary behaviourist you can find a list of Diplomates (individuals who have the highest level of training available in the field) at https://www.ecawbm.org/diplomates-list. In North America, you can find a directory of certified applied animal behaviorists at https://www.animalbehaviorsociety.org/web/committees-applied-behavior-directory.php and board certified veterinary behaviorists at: https://www.dacvb.org/search/custom.asp?id=4709. #petbehaviourodysseys, #whatmakesyouclick #PBO

The Fantasy/Animation Footnotes continue with this look at Disney authorship and the industry of animation via a turn to the celebrated Nine Old Men, a core group of directors and artists involved with the consolidated of the Disney aesthetic and a key component of its hyper-realist visual style. Listen as Chris maps some of the Nine Old Men's key personnel and their contribution to the refinement of animation's illusion of life credentials; questions of labour and the historical celebration of cel-animation's best practice; the highly gendered image of technological development and occlusion of women from Disney's production hierarchies; and the ongoing mythology that surrounds the Nine Old Men as masters of the medium. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

Explore how Francesca King, originally from London, made her journey to Wyoming and immersed herself in the literary scene. Her innovative Footnote Literary Consultancy is breaking new ground, offering writers in the state a chance to accelerate their journey to publication while fostering a sense of community. Join us as we talk about Francesca's journey from the eclectic streets of London to the tranquil plains of Wyoming, and how she is learning new ways to connect with writers across the state. She shares her journey and insights into the world of literary consultancy. Through Footnote, Francesca seeks to bridge the gap in Wyoming's literary landscape by offering professional editing services and creating a supportive community for writers. My special guest is Francesca King Francesca King, the visionary behind Footnote Literary Consultancy, provides editing and assessment services for fiction writers. She is an accomplished fiction writer with a master's degree in creative writing from London and extensive experience in the MFA program at the University of Wyoming. She holds an MA in Creative Writing from the University of London and an MFA in Fiction from the University of Wyoming, where she works as the Director of the Writing Center. Currently, she is immersed in crafting her latest novel, The Footnote, a captivating narrative inspired by her own life experiences. Her commitment to nurturing Wyoming's literary talent and providing accessible resources reflects her dedication to the creative writing community.   In this episode: Discover how Wyoming's creative economy can inspire your writing journey.  Learn the opportunities of creative startup efforts around Wyoming, ranging from film production and music to literary and visual arts. Be inspired to kickstart your own business and turn your passion into a profession.  Hear Francesca's view on the impact of AI on academic honesty and how it shapes the future of writing and research.  Find writers in your community to fuel your creativity and growth.  The resources mentioned in this episode are: Visit www.footnotelit.com to learn more about Footnote Literary Consultancy and its professional editing services, including personalized manuscript assessment and consulting.  Follow Footnote Literary Consultancy on Instagram at @footnotelit for updates, writing tips, and information about upcoming workshops and events.  Stay tuned on social media for updates on Francesca King's novel, The Footnote, and potential publication announcements.  Subscribe to the Winds of Change podcast and visit thinkwy.org for more thought-provoking episodes and stories from Wyoming Humanities Council. Follow Us on These Channels: https://www.linkedin.com/in/emydigrappa/ www.ThinkWY.org https://www.facebook.com/storiesaboutwhy https://www.instagram.com/storiesaboutwhy Listen on all your favorite platforms and subscribe! As always leave a review if you enjoyed these stories and follow us on Instagram or visit the webpage of the Wyoming Humanities!

Patrick McKenzie (@patio11) revisits his March 2023 essay that explained the dynamics of bank runs and system stress during the banking crisis one month prior. With data from a newly released Federal Reserve paper, he analyzes the true scope of the banking stress - including revelations that 22 banks experienced severe deposit outflows, far more than publicly known at the time. While officials blamed social media for bank runs, data shows institutional players, not retail depositors, drove the events. –Full transcript available here: www.complexsystemspodcast.com/banking-crisis-two-years-later/–Sponsors:  Vanta | GiveWell | CheckVanta automates security compliance and builds trust, helping companies streamline ISO, SOC 2, and AI framework certifications. Learn more at https://vanta.com/complexSupport proven charities that deliver measurable results and learn how to maximize your charitable impact with GiveWell. Go to givewell.org (and type in "Complex Systems" at checkout).Check is the leading payroll infrastructure provider and pioneer of embedded payroll. Check makes it easy for any SaaS platform to build a payroll business, and already powers 60+ popular platforms. Head to checkhq.com/complex and tell them patio11 sent you.–Links:Bits About Money: https://www.bitsaboutmoney.com/archive/banking-in-very-uncertain-times/Federal Reserve Report: Tracing Bank Runs in Real Time https://www.newyorkfed.org/research/staff_reports/sr1104.html Byrne Hobart's blog The Diff: https://www.thediff.co/ Matt Levine's blog Money Stuff: https://www.bloomberg.com/account/newsletters/money-stuff –Twitter:@patio11–Timestamps: (00:00) Revisiting the March 2023 essay(01:47) The Fed's study(11:21) Why are banks failing?(14:41) A useful heuristic from bond math(18:05) Sponsors: Vanta | Check(21:00) Maturity transformation(29:54) Sponsor: GiveWell(30:42) Liquidity problems are the proximate cause of bank failures(33:43) Trying to forestall a banking crisis(40:16) Deposit insurance expansion(47:12) Deposit insurance has some legacy issues(52:04) What would happen if my bank were to go into receivership this weekend?(59:46) What should users of the banking system do?(01:04:09) Parting thoughts(01:05:08) Footnote

This episode covers the next part of chapter 16: “The starry inscription at one's birth, I came to understand...” to “...the contrasts and relativities of the phenomenal universe.”  Summary: As Paramahansa Yogananda explains some detail surrounding the Yuga science as revealed to him by Swami Sri Yukteswar, we explore the depths of the teaching from a general perspective. The debate is made more nuanced as there are two schools of thought surrounding the Yugas – their length and the current age that we are in (ascending Dwapura not Kali).   0:00 Prior episode; 2:45 Man is not a puppet of the past; 10:50 Footnote about The Holy Science; 39:07 The concept of Yugas; 57:25 The footnote about our point in the Yuga cycle; 1:07:50 Looking ahead.  Links discussed in this episode: https://en.wikipedia.org/wiki/Kalpa_(time)  Homework for next episode— Read, absorb and make notes on the next part of chapter 16: “Men, one by one, escape from creation's prison...” to “…those that attain a liberating knowledge of the One Father.”  #autobiographyofayogi  #autobiographylinebyline  #paramahansayogananda Autobiography of a Yogi  awake.minute Self-Realization Fellowship Yogoda Satsanga Society of India #SRF #YSS

Inspired by the recent podcast episode discussing movie musical Wicked (John M. Chu, 2024), the first Fantasy/Animation Footnote of 2025 takes on the politics of film prequels, and how these curious entries into film series and the reflexive gestures that it often makes to earlier moments in a broader narrative offer up a way of understanding processes and theories of adaptation. Topics for this episode include the prequel's relationship to sequels, midquels, and remakes, and its broader fascination with chronology, history, and origin; the commercial value of prequels and the threat of temporality; cultural transference and how such adaptations highlight differences between media products; and the prequel's status as an evolving industrial category as much as a device used to tell a story. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

This week we speak with Christine Doublet from French food guide ‘Le Fooding’. Plus two new magazines, ‘Footnote’ by Alex Hunting and ‘Wonderwhy’ by Hana Irena. See omnystudio.com/listener for privacy information.

Full Video Series at Mary Wollstonecraft goes off on Rousseau, hoisting him with his own Petard, as it were.* 00:00 Opening 00:57 I Have Notes 06:26 CHAPTER 3 06:44 Introduction to Bodily Strength and Gender 07:34 Misconceptions About Genius and Health 10:21 The Superiority Debate: Men vs. Women 11:43 ROUSSEAU Footnote: Why Women Can't ________ 17:38 Education and Female Virtue 19:01 EXTENSIVE   FOOTNOTE from Mr. Day's "Sandford and Merton", Vol III 22:30  Critique of Rousseau's Views on Women 27:11 ROUSSEAU Quote re Girls & Dolls & Coquettes 30:39 ROUSSEAU Footnote on Girl Writing the Letter "O" 36:30 The Consequences of Female Subjugation 38:05 The Call for Rational Education 40:51 The Corruption of Power and Female Dignity 41:24 Revolutionizing Female Manners 44:55 The Nature of Worship and Rational Conduct 47:20 The Role of Women in Society 51:53 The Consequences of Dependence 54:36 ROUSSEAU Footnote: Men Have All The Good Qualities (sorry ladies!) 01:02:06 ROUSSEAU Footnote - "How Lovely is Her Ignorance" 01:07:13 Summing Up: The Call for Rational Virtues 01:10:53 Outro • Xiran Jay Zhao, Author of "Iron Widow" has an amazing Channel chock full of things you never knew you needed to learn—but you do.    /   • If you've never read Anne Brontë, please take a listen to CraftLit's "The Tenant of Wildfell Hall" (starts with episode 516—). She's the most shocking, most modern, and arguably the best of the Brontë writers. You likely missed her b/c Charlotte didn't like this book's 'sensibilities' and did what she could to ghost it after Anne's death. Bad Charlotte! *The phrase's meaning is that a bomb-maker is blown ("hoist", the past tense of "hoise") off the ground by his own bomb ("petard"), and indicates an ironic reversal or poetic justice. []

Ryan Diaz

Sexy young revolutionaries, a queer romance, and international communism--what more could you ask for?! In his brilliant new book, Hotel Lux: An Intimate History of Communism's Forgotten Radicals (Footnote Press, 2024), Maurice Casey delivers up an intriguing story of friendship, love, and revolution in a story spanning decades and continents. Following May O'Callaghan, an Irish communist revolutionary with an impressive curricula vitae, and her two dearest friends Nellie Cohen and Emmy Leonhard, Casey takes us from London to Moscow to New York City to Mexico. In a clever narrative intervention, Casey also takes us with him to an attic in the Cotswolds and a shed in Galicia as he documents his own journey in researching this book. He tells his research story in a way that draws back the curtain not just on the immensely complex process of collecting the pieces of this narrative, but also on the duality of doing historical research: equal parts thrilling and heartbreaking. Join us as we chat about political intrigue, a host of fascinating--famous or forgotten--twentieth-century revolutionaries, an enduring friendship that built the blocks for a queer romance captured in incredible love letters, and one historian's determination to follow the breadcrumbs to the satisfying conclusion of an international story. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this solo episode, I share the story of how an accidental footnote in my sociology degree led me to discover my life's work and create the world's first Motherhood Studies Practitioner Certification. Before its evolution in 2025, I'm offering this Legacy Edition of the certification with its foundational curriculum one final time - and at a $1,000AUD discount. In this episode I share what I'm doing differently next year, my thoughts on the current and future landscape of mother-support, and what makes this Legacy Edition special. Note: The Legacy Edition special offer is closing soon. The program is in complete self-study mode to complete at your own pace, is discounted by $1,000AUD, and is available on a 12 month payment plan. If you want to be part of creating real change in how we value and support mothers, this is for you. Learn more and join here: https://drsophiebrock.com/motherhoodstudies/ Resources Mentioned: The Fish Tank of Motherhood animation - https://drsophiebrock.com/thefishtankofmotherhood Graduate stories and transformations - https://drsophiebrock.com/clientfeedback Legacy Edition enrollment details - https://motherhoodstudies.newzenler.com/courses/legacyedition/buy/plan/150974

Patrick Boatwright

Fantasy/Animation welcomes back special guest Professor Terry Lindvall to the podcast to continue the discussion of C.S. Lewis, this time with a focus on Lewis' own work on fairy stories and the value the writer places on the importance of the ‘unexpected' in fairytales as a mode of narration. Topics include Lewis' professional history and views on the crafting of child curiosity within the literary imagination; how Lewis' own students were directed to bring back enchantment via side stories and personal images of haunting; Lewis' use of female characters, storytelling, and questions of empowerment; distinctions in worldbuilding and world creation between Lewis and J. R. R. Tolkien; and the qualities that make Lewis such a seminal writer of popular fantasy. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

Patrick Boatwright

A leader for conducting rigorous randomized trials of humans along with animal models for understanding nutrition and metabolism, Dr. Kevin Hall is a Senior Investigator at the National Institutes of Health, and Section Chief of the Integrative Physiology Section, NIDDK. In this podcast, we reviewed his prolific body of research a recent publications. The timing of optimizing our diet and nutrition seems apropos, now that we're in in the midst of the holiday season!Below is a video snippet of our conversation on his ultra-processed food randomized trial.Full videos of all Ground Truths podcasts can be seen on YouTube here. The current one is here. If you like the YouTube format, please subscribe! The audios are also available on Apple and Spotify.Note: I'll be doing a Ground Truths Live Chat on December 11th at 12 N EST, 9 AM PST, so please mark your calendar and join!Transcript with links to publications and audioEric Topol (00:05):Well, hello. This is Eric Topol with Ground Truths, and I'm really delighted to have with me today, Dr. Kevin Hall from the NIH. I think everybody knows that nutrition is so important and Kevin is a leader in doing rigorous randomized trials, which is not like what we usually see with large epidemiologic studies of nutrition that rely on food diaries and the memory of participants. So Kevin, it's really terrific to have you here.Kevin Hall (00:34):Thanks so much for the invitation.Ultra-Processed FoodsEric Topol (00:36):Yeah. Well, you've been prolific and certainly one of the leaders in nutrition science who I look to. And what I thought we could do is go through some of your seminal papers. There are many, but I picked a few and I thought we'd first go back to the one that you published in Cell Metabolism. This is ultra-processed diets cause excessive caloric intake and weight gain. (Main results in graph below.) So maybe you can take us through the principle findings from that trial.Kevin Hall (01:10):Yeah, sure. So that was a really interesting study because it's the first randomized control trial that's investigated the role of ultra-processed foods in potentially causing obesity. So we've got, as you mentioned, lots and lots of epidemiological data that have made these associations between people who consume diets that are very high in ultra-processed foods as having greater risk for obesity. But those trials are not demonstrating causation. I mean, they suggest a strong link. And in fact, the idea of ultra-processed foods is kind of a new idea. It's really sort of appeared on the nutrition science stage probably most prominently in the past 10 years or so. And I first learned about this idea of ultra-processed foods, which is really kind of antithetical to the way most nutrition scientists think about foods. We often think about foods as nutrient delivery vehicles, and we kind of view foods as being the fraction of carbohydrates versus fats in them or how much sodium or fiber is in the foods.Kevin Hall (02:17):And along came this group in Brazil who introduced this new way of classifying foods that completely ignores the nutrient composition and says what we should be doing is classifying foods based on the extent and purpose of processing of foods. And so, they categorize these four different categories. And in the fourth category of this so-called NOVA classification scheme (see graphic below) , they identified something called ultra-processed foods. There's a long formal definition and it's evolved a little bit over the years and continues to evolve. But the basic ideas that these are foods that are manufactured by industries that contain a lot of purified ingredients made from relatively cheap agricultural commodity products that basically undergo a variety of processes and include additives and ingredients that are not typically found in home kitchens, but are typically exclusively in manufactured products to create the wide variety of mostly packaged goods that we see in our supermarkets.Kevin Hall (03:22):And so, I was really skeptical that there was much more about the effects of these foods. Other than that they typically have high amounts of sugar and saturated fat and salt, and they're pretty low in fiber. And so, the purpose of this study was to say, okay, well if there's something more about the foods themselves that is causing people to overconsume calories and gain weight and eventually get obesity, then we should do a study that's trying to test for two diets that are matched for these various nutrients of concern. So they should be matched for the macronutrients, they should be matched for the sugar content, the fat, the sodium, the fiber, and people should just be allowed to eat whatever they want and they shouldn't be trying to change their weight in any way. And so, the way that we did this was, as you mentioned, we can't just ask people to report what they're eating.Kevin Hall (04:19):So what we did was we admitted these folks to the NIH Clinical Center and to our metabolic ward, and it's a very artificial environment, but it's an environment that we can control very carefully. And so, what we basically did is take control over their food environment and we gave them three meals a day and snacks, and basically for a two-week period, they had access to meals that were more than 80% of calories coming from ultra-processed foods. And then in random order, they either received that diet first and give them simple instructions, eat as much as little as you want. We're going to measure lots of stuff. You shouldn't be trying to change your weight or weight that gave them a diet that had no calories from ultra-processed foods. In fact, 80% from minimally processed foods. But again, both of these two sort of food environments were matched for these nutrients that we typically think of as playing a major role in how many calories people choose to eat.Kevin Hall (05:13):And so, the basic idea was, okay, well let's measure what these folks eat. We gave them more than double the calories that they would require to maintain their weight, and what they didn't know was that in the basement of the clinical center where the metabolic kitchen is, we had all of our really talented nutrition staff measuring the leftovers to see what it was that they didn't eat. So we knew exactly what we provided to them and all the foods had to be in our nutrition database and when we compute what they actually ate by difference, so we have a very precise estimate about not only what foods they chose to ate, but also how many calories they chose to eat, as well as the nutrient composition.And the main upshot of all that was that when these folks were exposed to this highly ultra-processed food environment, they spontaneously chose to eat about 500 calories per day more over the two-week period they were in that environment then when the same folks were in the environment that had no ultra-processed foods, but just minimally processed foods. They not surprisingly gained weight during the ultra-processed food environment and lost weight and lost body fat during the minimally processed food environment. And because those diets were overall matched for these different nutrients, it didn't seem to be that those were the things that were driving this big effect. So I think there's a couple of big take homes here. One is that the food environment really does have a profound effect on just the biology of how our food intake is controlled at least over relatively short periods of time, like the two-week periods that we were looking at. And secondly, that there's something about ultra-processed foods that seem to be driving this excess calorie intake that we now know has been linked with increased risk of obesity, and now we're starting to put some of the causal pieces together that really there might be something in this ultra-processed food environment that's driving the increased rates of obesity that we've seen over the past many decades.Eric Topol (07:18):Yeah, I mean I think the epidemiologic studies that make the link between ultra-processed foods and higher risk of cancer, cardiovascular disease, type 2 diabetes, neurodegenerative disease. They're pretty darn strong and they're backed up by this very rigorous study. Now you mentioned it short term, do you have any reason to think that adding 500 calories a day by eating these bad foods, which by the way in the American diet is about 60% or more of the average American diet, do you have any inkling that it would change after a few weeks?Kevin Hall (07:54):Well, I don't know about after a few weeks, but I think that one of the things that we do know about body weight regulation and how it changes in body weight impact both metabolism, how many calories were burning as well as our appetite. We would expect some degree of moderation of that effect eventually settling in at a new steady state, that's probably going to take months and years to achieve. And so the question is, I certainly don't believe that it would be a 500 calorie a day difference indefinitely. The question is when would that difference converge and how much weight would've been gained or lost when people eventually reached that new plateau? And so, that's I think a really interesting question. Some folks have suggested that maybe if you extrapolated the lines a little bit, you could predict when those two curves might eventually converge. That's an interesting thought experiment, but I think we do need some longer studies to investigate how persistent are these effects. Can that fully explain the rise in average body weight and obesity rates that have occurred over the past several decades? Those are open questions.Eric Topol (09:03):Yeah. Well, I mean, I had the chance to interview Chris van Tulleken who wrote the book, Ultra-Processed People and I think you might remember in the book he talked about how he went on an ultra-processed diet and gained some 20, 30 pounds in a short time in a month. And his brother, his identical twin brother gained 50, 60 pounds, and so it doesn't look good. Do you look at all the labels and avoid all this junk and ultra-processed food now or are you still thinking that maybe it's not as bad as it looks?Kevin Hall (09:38):Well, I mean I think that I certainly learned a lot from our studies, and we are continuing to follow this up to try to figure out what are the mechanisms by which this happen. But at the same time, I don't think we can throw out everything else we know about nutrition science. So just because we match these various nutrients in this particular study, I think one of the dangers here is that as you mentioned, there's 60% of the food environment in the US and Great Britain and other places consist of these foods, and so they're unavoidable to some extent, right? Unless you're one of these privileged folks who have your backyard garden and your personal chef who can make all of your foods, I'm certainly not one of those people, but for the vast majority of us, we're going to have to incorporate some degree of ultra-processed foods in our day-to-day diet.Kevin Hall (10:24):The way I sort of view it is, we really need to understand the mechanisms and before we understand the mechanisms, we have to make good choices based on what we already know about nutrition science, that we should avoid the foods that have a lot of sugar in them. We should avoid foods that have a lot of saturated fat and sodium. We should try to choose products that contain lots of whole grains and legumes and fruits and vegetables and things like that. And there's some of those, even in the ultra-processed food category. I pretty regularly consume a microwavable ready meal for lunch. It tends to be pretty high in whole grains and legumes and low in saturated fat and sugar and things like that. But to engineer a food that can heat up properly in a microwave in four minutes has some ultra-processing technology involved there. I would be pretty skeptical that that's going to cause me to have really poor health consequences as compared to if I had the means to eat homemade French fries every day in tallow. But that's the kind of comparison that we have to think about.Eric Topol (11:36):But I think what you're touching on and maybe inadvertently is in that NOVA class four, the bad ultra-processed foods, there's a long, long list of course, and some of those may be worse than others, and we haven't seen an individual ranking of these constituents. So as you're alluding to what's in that microwave lunch probably could be much less concerning than what's in these packaged snacks that are eaten widely. But I would certainly agree that we don't know everything about this, but your study is one of the most quoted studies ever in the ultra-processed food world. Now, let me move on to another trial that was really important. This was published in Nature Medicine and it's about a plant-based diet, which is of course a very interesting diet, low-fat versus an animal-based ketogenic diet. Also looking at energy intake. Can you take us through that trial?Plant-Based, Low Fat Diet vs Animal-Based, Low Carbohydrate Ketogenic DietKevin Hall (12:33):Sure. So it's actually interesting to consider that trial in the context of the trial we just talked about because both of these diets that we tested in this trial were relatively low in ultra-processed foods, and so both of them contained more than a kilogram of non-starchy vegetables as a base for designing these, again, two different food environments. Very similar overall study design where people again were exposed to either diets that were vegan plant-based diet that was really high in starches and was designed to kind of cause big insulin increases in the blood after eating the meals. And the other diet had very, very few carbohydrates of less than 10% in total, and we built on that kind of non-starchy vegetable base, a lot of animal-based products to kind of get a pretty high amount of fat and having very low carbohydrates. Both diets in this case, like I mentioned, were pretty low in ultra-processed foods, but what we were really interested in here was testing this idea that has come to prominence recently, that high carbohydrate diets that lead to really large glucose excursions after meals that cause very high insulin levels after meals are particularly obesogenic and should cause you to be hungrier than compared to a diet that doesn't lead to those large swings in glucose and insulin and the prototypical case being one that's very low in carbohydrate and might increase the level of ketones that are floating around in your blood, which are hypothesized to be an appetite suppressant. Same sort of design, these minimally processed diets that one was very high in carbs and causes large swings in insulin and the other that's very low in carbs and causes increases in ketones.Kevin Hall (14:22):We ask people, again, while you're in one food environment or the other, don't be trying to gain weight or lose weight, eat as much or as little as you'd like, and we're going to basically measure a lot of things. They again, don't know what the primary outcome of the study is. We're measuring their leftovers afterwards. And so, the surprise in this particular case was that the diet that caused the big swings in glucose and insulin did not lead to more calorie consumption. In fact, it led to about 700 calories per day less than when the same people were exposed to the ketogenic diet. Interestingly, both food environments caused people to lose weight, so it wasn't that we didn't see the effect of people over consuming calories on either diet, so they were reading fewer calories in general than they were when they came in, right. They're probably eating a pretty ultra-processed food diet when they came in. We put them on these two diets that varied very much in terms of the macronutrients that they were eating, but both were pretty minimally processed. They lost weight. They ended up losing more body fat on the very low-fat high carb diet than the ketogenic diet, but actually more weight on the ketogenic diet than the low-fat diet. So there's a little bit of a dissociation between body fat loss and weight loss in this study, which was kind of interesting.Eric Topol (15:49):Interesting. Yeah, I thought that was a fascinating trial because plant-based diet, they both have their kind of camps, you know.Kevin Hall (15:57):Right. No, exactly.Immune System Signatures for Vegan vs Ketogenic DietsEric Topol (15:58):There are people who aren't giving up on ketogenic diet. Of course, there's some risks and some benefits and there's a lot of interest of course with the plant-based diet. So it was really interesting and potentially the additive effects of plant-based with avoidance or lowering of ultra-processed food. Now, the more recent trial that you did also was very interesting, and of course I'm only selecting ones that I think are particularly, there are a lot of trials you've done, but this one is more recent in this year where you looked at vegan versus ketogenic diets for the immune signature, immune response, which is really important. It's underplayed as its effect, and so maybe you can take us through that one.[Link to a recent Nature feature on this topic, citing Dr. Hall's work]Kevin Hall (16:43):Yeah, so just to be clear, it's actually the same study, the one that we just talked about. This is a secondary sort of analysis from a collaboration we had with some folks at NIAID here at the NIH to try to evaluate immune systems signatures in these same folks who wonder what these two changes in their food environment. One is vegan, high carbohydrate low-fat diet and the other, the animal-based ketogenic diet. And again, it was pretty interesting to me that we were able to see really substantial changes in how the immune system was responding. First of all, both diets again seem to have improved immune function, both adaptive and innate immune function as compared to their baseline measurements when they came into the study. So when they're reading their habitual diet, whatever that is typically high in ultra-processed foods, they switched to both of these diets.Kevin Hall (17:39):We saw market changes in their immune system even compared to baseline. But when we then went and compared the two diets, they were actually divergent also, in other words, the vegan diet seemed to stimulate the innate immune system and the ketogenic diet seemed to stimulate the adaptive immune system. So these are the innate immune system can be thought of. Again, I'm not an immunologist. My understanding is that this is the first line defense against pathogens. It happens very quickly and then obviously the adaptive immune system then adapts to a specific pathogen over time. And so, this ability of our diet to change the immune system is intriguing and how much of that has to do with influencing the gut microbiota, which obviously the gut plays a huge role in steering our immune system in one direction versus another. I think those are some really intriguing mechanistic questions that are really good fodder for future research.Eric Topol (18:42):Yeah, I think it may have implications for treatment of autoimmune diseases. You may want to comment about that.Kevin Hall (18:51):Yeah, it's fascinating to think about that the idea that you could change your diet and manipulate your microbiota and manipulate your gut function in a way to influence your immune system to steer you away from a response that may actually be causing your body damage in your typical diet. It's a fascinating area of science and we're really interested to follow that up. I mean, it kind of supports these more anecdotal reports of people with lupus, for example, who've reported that when they try to clean up their diet for a period of time and eliminate certain foods and eliminate perhaps even ultra-processed food products, that they feel so much better that their symptoms alleviate at least for some period of time. Obviously, it doesn't take the place of the therapeutics that they need to take, but yeah, we're really interested in following this up to see what this interaction might be.Eric Topol (19:46):Yeah, it's fascinating. It also gets to the fact that certain people have interesting responses. For example, those with epilepsy can respond very well to a ketogenic diet. There's also been diet proposed for cancer. In fact, I think there's some even ongoing trials for cancer of specific diets. Any comments about that?Kevin Hall (20:10):Yeah, again, it's a really fascinating area. I mean, I think we kind of underappreciate and view diet in this lens of weight loss, which is not surprising because that's kind of where it's been popularized. But I think the role of nutrition and how you can manipulate your diet and still you can have a very healthy version of a ketogenic diet. You can have a very healthy version of a low-fat, high carb diet and how they can be used in individual cases to kind of manipulate factors that might be of concern. So for example, if you're concerned about blood glucose levels, clearly a ketogenic diet is moderating those glucose levels over time, reducing insulin levels, and that might have some positive downstream consequences and there's some potential downsides. Your apoB levels might go up. So, you have to kind of tune these things to the problems and the situations that individuals may face. And similarly, if you have issues with blood glucose control, maybe a high carbohydrate diet might not be for you, but if that's not an issue and you want to reduce apoB levels, it seems like that is a relatively effective way to do that, although it does tend to increase fasting triglyceride levels.Kevin Hall (21:27):So again, there's all of these things to consider, and then when you open the door beyond traditional metabolic health markers to things like inflammation and autoimmune disease as well as some of these other things like moderating how cancer therapeutics might work inside the body. I think it's a really fascinating and interesting area to pursue.Eric Topol (21:55):No question about it. And that also brings in the dimension of the gut microbiome, which obviously your diet has a big influence, and it has an influence on your brain, brain-gut axis, and the immune system. It's all very intricate, a lot of feedback loops and interactions that are not so easy to dissect, right?Kevin Hall (22:16):Absolutely. Yeah, especially in humans. That's why we rely on our basic science colleagues to kind of figure out these individual steps in these chains. And of course, we do need human experiments and carefully controlled experiments to see how much of that really translates to humans, so we need this close sort of translational partnership.On the Pathogenesis of Obesity, Calories In and Calories OutEric Topol (22:35):Yeah. Now, you've also written with colleagues, other experts in the field about understanding the mechanisms of pathogenesis of obesity and papers that we'll link to. We're going to link to everything for what we've been discussing about calories in, calories out, and that's been the longstanding adage about this. Can you enlighten us, what is really driving obesity and calories story?Kevin Hall (23:05):Well, I co-organized a meeting for the Royal Society, I guess about a year and a half ago, and we got together all these experts from around the world, and the basic message is that we have lots of competing theories about what is driving obesity. There's a few things that we all agree on. One is that there is a genetic component. That adiposity in a given environment is somewhere between 40% to 70% heritable, so our genes play a huge role. It seems like there's certain genes that can play a major role. Like if you have a mutation in leptin, for example, or the leptin receptor, then this can have a monogenic cause of obesity, but that's very, very rare. What seems to be the case is that it's a highly polygenic disease with individual gene variants contributing a very, very small amount to increased adiposity. But our genes have not changed that much as obesity prevalence has increased over the past 50 years. And so, something in the environment has been driving that, and that's where the real debates sort of starts, right?Kevin Hall (24:14):I happen to be in the camp that thinks that the food environment is probably one of the major drivers and our food have changed substantially, and we're trying to better understand, for example, how ultra-processed foods which have risen kind of in parallel with the increased prevalence of obesity. What is it about ultra-processed foods that tend to drive us to overconsume calories? Other folks focus maybe more on what signals from the body have been altered by the foods that we're eating. They might say that the adipose tissue because of excess insulin secretion for example, is basically driven into a storage mode and that sends downstream signals that are eventually sensed by the brain to change our appetite and things like that. There's a lot of debate about that, but again, I think that these are complementary hypotheses that are important to sort out for sure and important to design experiments to try to figure out what is more likely. But there is a lot of agreement on the idea that there's something in our environment has changed.Kevin Hall (25:17):I think there's even maybe a little bit less agreement of exactly what that is. I think that there's probably a little bit more emphasis on the food environment as opposed to there are other folks who think increased pollution might be driving some of this, especially endocrine disrupting chemicals that have increased in prevalence. I think that's a viable hypothesis. I think we have to try to rank order what we think are the most likely and largest contributors. They could all be contributing to some extent and maybe more so in some people rather than others, but our goal is to try to, maybe that's a little simple minded, but let's take the what I think is the most important thing and let's figure out the mechanisms of that most important thing and we'll, number one, determine if it is the most important thing. In my case, I think something about ultra-processed foods that are driving much of what we're seeing. If we could better understand that, then we could both advise consumers to avoid certain kinds of foods because of certain mechanisms and still be able to consume some degree of ultra-processed foods. They are convenient and tasty and relatively inexpensive and don't require a lot of skill and equipment to prepare. But then if we focus on the true bad guys in that category because we really understand the mechanisms, then I think that would be a major step forward. But that's just my hypothesis.Eric Topol (26:43):Well, I'm with you actually. Everything I've read, everything I've reviewed on ultra-processed food is highly incriminating, and I also get frustrated that nothing is getting done about it, at least in this country. But on the other hand, it doesn't have to be either or, right? It could be both these, the glycemic index story also playing a role. Now, when you think about this and you're trying to sort out calories in and calories out, and let's say it's one of your classic experiments where you have isocaloric proteins and fat and carbohydrate exactly nailed in the different diets you're examining. Is it really about calories or is it really about what is comprising the calorie?Kevin Hall (27:29):Yeah, so I think this is the amazing thing, even in our ultra-processed food study, if we asked the question across those people, did the people who ate more calories even in the ultra-processed diet, did they gain more weight? The answer is yes.Kevin Hall (27:44):There's a very strong linear correlation between calorie intake and weight change. I tend to think that I started my career in this space focusing more on the metabolism side of the equation, how the body's using the calories and how much does energy expenditure change when you vary the proportion of carbs versus fat, for example. The effect size is there, they might be there, but they're really tiny of the order of a hundred calories per day. What really struck me is that when we just kind of changed people's food environments, the magnitude of the effects are like we mentioned, 500 to 700 calories per day differences. So I think that the real trick is to figure out how is it that the brain is regulating our body weight in some way that we are beginning to understand from a molecular perspective? What I think is less well understood is, how is that food intake control system altered by the food environment that we find ourselves in?The Brain and GLP-1 DrugsKevin Hall (28:42):There are a few studies now in mice that are beginning to look at how pathways in the brain that have been believed to be related to reward and not necessarily homeostatic control of food intake. They talk to the regions of the brain that are related to homeostatic control of food intake, and it's a reciprocal sort of feedback loop there, and we're beginning to understand that. And I think if we get more details about what it is in our foods that are modulating that system, then we'll have a better understanding of what's really driving obesity and is it different in different people? Are there subcategories of obesity where certain aspects of the food environment are more important than others, and that might be completely flipped in another person. I don't know the answer to that question yet, but it seems like there are certain common factors that might be driving overall changes in obesity prevalence and how they impact this reward versus homeostatic control systems in the brain, I think are really fascinating questions.Eric Topol (29:43):And I think we're getting much more insight about this circuit of the reward in the brain with the food intake, things like optogenetics, many ways that we're getting at this. And so, it's fascinating. Now, that gets me to the miracle drug class GLP-1, which obviously has a big interaction with obesity, but of course much more than that. And you've written about this as well regarding this topic of sarcopenic obesity whereby you lose a lot of weight, but do you lose muscle mass or as you referred to earlier, you lose body fat and maybe not so much muscle mass. Can you comment about your views about the GLP-1 family of drugs and also about this concern of muscle mass loss?Kevin Hall (30:34):Yeah, so I think it's a really fascinating question, and we've been trying to develop mathematical models about how our body composition changes with weight gain and weight loss for decades now. And this has been a long topic, one of the things that many people may not realize is that people with obesity don't just have elevated adiposity, they also have elevated muscle mass and lean tissue mass overall. So when folks with obesity lose weight, and this was initially a pretty big concern with bariatric surgery, which has been the grandfather of ways that people have lost a lot of weight. The question has been is there a real concern about people losing too much weight and thereby becoming what you call sarcopenic? They have too little muscle mass and then they have difficulties moving around. And of course, there are probably some people like that, but I think what people need to realize is that folks with obesity tend to start with much higher amounts of lean tissue mass as well as adiposity, and they start off with about 50% of your fat-free mass, and the non-fat component of your body is skeletal muscle.Kevin Hall (31:45):So you're already starting off with quite a lot. And so, the question then is when you lose a lot of weight with the GLP-1 receptor agonist or with bariatric surgery, how much of that weight loss is coming from fat-free mass and skeletal muscle versus fat mass? And so, we've been trying to simulate that using what we've known about bariatric surgery and what we've known about just intentional weight loss or weight gain over the years. And one of the things that we found was that our sort of expectations for what's expected for the loss of fat-free mass with these different drugs as well as bariatric surgery, for the most part, they match our expectations. In other words, the expected amount of fat loss and fat free mass loss. The one outlier interestingly, was the semaglutide study, and in that case, they lost more fat-free mass than would be expected.Kevin Hall (32:44):Now, again, that's just raising a little bit of a flag that for whatever reason, from a body composition perspective, it's about a hundred people underwent these repeated DEXA scans in that study sponsored by Novo Nordisk. So it's not a huge number of people, but it's enough to really get a good estimate about the proportion of weight loss. Whether or not that has functional consequences, I think is the open question. There's not a lot of reports of people losing weight with semaglutide saying, you know what? I'm really having trouble actually physically moving around. I feel like I've lost a lot of strength. In fact, it seems to be the opposite, right, that the quality of the muscle there seems to be improved. They seem to have more physical mobility because they've lost so much more weight, that weight had been inhibiting their physical movement in the past.Kevin Hall (33:38):So it's something to keep an eye on. It's an open question whether or not we need additional therapies in certain categories of patients, whether that be pharmacological, there are drugs that are interesting that tend to increase muscle mass. There's also other things that we know increase muscle mass, right? Resistance exercise training, increase this muscle mass. And so, if you're really concerned about this, I certainly, I'm not a physician, but I think it's something to consider that if you go on one of these drugs, you might want to think about increasing your resistance exercise training, maybe increasing the protein content of your diet, which then can support that muscle building. But I think it's a really interesting open question about what the consequences of this might be in certain patient populations, especially over longer periods of time.Dietary Protein, Resistance Exercise, DEXA ScansEric Topol (34:30):Yeah, you've just emphasized some really key points here. Firstly, that resistance exercise is good for you anyway. And get on one of these drugs, why don't you amp it up or get it going? The second is about the protein diet, which it'd be interesting to get your thoughts on that, but we generally have too low of a protein diet, but then there are some who are advocating very high protein diets like one gram per pound, not just one gram per kilogram. And there have been studies to suggest that that very high protein diet could be harmful, but amping up the protein diet, that would be a countering thing. But the other thing you mentioned is a DEXA scan, which can be obtained very inexpensively, and because there's a variability in this muscle mass loss if it's occurring, I wonder if that's a prudent thing or if you just empirically would just do the things that you mentioned. Do you have any thoughts about that?Kevin Hall (35:32):Yeah, that's really a clinical question that I don't deal with on a day-to-day basis. And yeah, I think there's probably better people suited to that. DEXA scans, they're relatively inexpensive, but they're not readily accessible to everyone. I certainly wouldn't want to scare people away from using drugs that are now known to be very effective for weight loss and pretty darn safe as far as we can tell, just because they don't have access to a DEXA scanner or something like that.Eric Topol (36:00):Sure. No, that makes a lot of sense. I mean, the only reason I thought it might be useful is if you're concerned about this and you want to track, for example, how much is that resistant training doing?Kevin Hall (36:13):But I think for people who have the means to do that, sure. I can't see any harm in it for sure.Continuous Glucose Sensors?Eric Topol (36:19):Yeah. That gets me to another metric that you've written about, which is continuous glucose tracking. As you know, this is getting used, I think much more routinely in type one insulin diabetics and people with type 2 that are taking insulin or difficult to manage. And now in recent months there have been consumer approved that is no prescription needed, just go to the drugstore and pick up your continuous glucose sensor. And you've written about that as well. Can you summarize your thoughts on it?Kevin Hall (36:57):Yeah, sure. I mean, yeah, first of all, these tools have been amazing for people with diabetes and who obviously are diagnosed as having a relative inability to regulate their glucose levels. And so, these are critical tools for people in that population. I think the question is are they useful for people who don't have diabetes and is having this one metric and where you target all this energy into this one thing that you can now measure, is that really a viable way to kind of modulate your lifestyle and your diet? And how reliable are these CGM measurements anyway? In other words, do they give the same response to the same meal on repeated occasions? Does one monitor give the same response as another monitor? And those are the kinds of experiments that we've done. Again, secondary analysis, these trials that we talked about before, we have people wearing continuous glucose monitors all the time and we know exactly what they ate.Kevin Hall (37:59):And so, in a previous publication several years ago, we basically had two different monitors. One basically is on the arm, which is the manufacturer's recommendation, the other is on the abdomen, which is the manufacturer's recommendation. They're wearing them simultaneously. And we decided just to compare what were the responses to the same meals in simultaneous measurements. And they were correlated with each other thankfully, but they weren't as well predictive as you might expect. In other words, one device might give a very high glucose reading to consuming one meal and the other might barely budge, whereas the reverse might happen for a different meal. And so, we asked the question, if we were to rank the glucose spikes by one meal, so we have all these meals, let's rank them according to the glucose spikes of one device. Let's do the simultaneous measurements with the other device.Kevin Hall (38:53):Do we get a different set of rankings? And again, they're related to each other, but they're not overlapping. They're somewhat discordant. And so, then the question becomes, okay, well if I was basically using this one metric to kind of make my food decisions by one device, I actually start making different decisions compared to if I happen to have been wearing a different device. So what does this really mean? And I think this sort of foundational research on how much of a difference you would need to make a meaningful assessment about, yeah, this is actionable from a lifestyle perspective, even if that is the one metric that you're interested in. That sort of foundational research I don't think has really been done yet. More recently, we asked the question, okay, let's ignore the two different devices. Let's stick to the one where we put it on our arm, and let's ask the question.Kevin Hall (39:43):We've got repeated meals and we've got them in this very highly regimented and controlled environment, so we know exactly what people ate previously. We know the timing of the meals, we know when they did their exercise, we know how much they were moving around, how well they slept the night before. All of these factors we could kind of control. And the question that we asked in that study was, do people respond similarly to the same meal on repeated occasions? Is that better than when you actually give them very different meals? But they match overall for macronutrient content, for example. And the answer to that was surprisingly no. We had as much variability in the glucose response to the same person consuming the same meal on two occasions as a whole bunch of different meals. Which suggests again, that there's enough variability that it makes it difficult to then recommend on for just two repeats of a meal that this is going to be a meal that's going to cause your blood glucose to be moderate or blood glucose to be very high. You're going to have to potentially do this on many, many different occasions to kind of figure out what's the reliable response of these measurements. And again, that foundational research is typically not done. And I think if we're really going to use this metric as something that is going to change our lifestyles and make us choose some meals other than others, then I think we need that foundational research. And all we know now is that two repeats of the same meal is not going to do it.Eric Topol (41:21):Well, were you using the current biosensors of 2024 or were you using ones from years ago on that?Kevin Hall (41:27):No, we were using ones from several years ago when these studies were completed. But interestingly, the variability in the venous measurements to meal tests is also very, very different. So it's probably not the devices per se that are highly variable. It's that we don't really know on average how to predict these glucose responses unless there's huge differences in the glycemic load. So glycemic load is a very old concept that when you have very big differences in glycemic load, yeah, you can on average predict that one kind of meal is going to give rise to a much larger glucose excursion than another. But typically these kind of comparisons are now being made within a particular person. And we're comparing meals that might have quite similar glycemic loads with the claim that there's something specific about that person that causes them to have a much bigger glucose spike than another person. And that we can assess that with a couple different meals.Eric Topol (42:31):But also, we know that the spikes or the glucose regulation, it's very much affected by so many things like stress, like sleep, like exercise. And so, it wouldn't be at all surprising that if you had the exact same food, but all these other factors were modulated that it might not have the same response. But the other thing, just to get your comment on. Multiple groups, particularly starting in Israel, the Weizmann Institute, Eran Segal and his colleagues, and many subsequent have shown that if you give the exact same amount of that food, the exact same time to a person, they eat the exact same amount. Their glucose response is highly heterogeneous and variable between people. Do you think that that's true? That in fact that our metabolism varies considerably and that the glucose in some will spike with certain food and some won't.Kevin Hall (43:29):Well, of course that's been known for a long time that there's varying degrees of glucose tolerance. Just oral glucose tolerance tests that we've been doing for decades and decades we know is actually diagnostic, that we use variability in that response as diagnostic of type 2 diabetes.Eric Topol (43:49):I'm talking about within healthy people.Kevin Hall (43:53):But again, it's not too surprising that varying people. I mean, first of all, we have a huge increase in pre-diabetes, right? So there's various degrees of glucose tolerance that are being observed. But yeah, that is important physiology. I think the question then is within a given person, what kind of advice do we give to somebody about their lifestyle that is going to modulate those glucose responses? And if that's the only thing that you look at, then it seems like what ends up happening, even in the trials that use continuous glucose monitors, well big surprise, they end up recommending low carbohydrate diets, right? So that's the precision sort of nutrition advice because if that's the main metric that's being used, then of course we've all known for a very long time that lower carbohydrate diets lead to a moderated glucose response compared to higher carbohydrate diets. I think the real question is when you kind of ask the issue of if you normalize for glycemic load of these different diets, and there are some people that respond very differently to the same glycemic load meal compared to another person, is that consistent number one within that person?Kevin Hall (45:05):And our data suggests that you're going to have to repeat that same test multiple times to kind of get a consistent response and be able to make a sensible recommendation about that person should eat that meal in the future or not eat that meal in the future. And then second, what are you missing when that becomes your only metric, right? If you're very narrowly focused on that, then you're going to drive everybody to consume a very low carbohydrate diet. And as we know, that might be great for a huge number of people, but there are those that actually have some deleterious effects of that kind of diet. And if you're not measuring those other things or not considering those other things and put so much emphasis on the glucose side of the equation, I worry that there could be people that are being negatively impacted. Not to mention what if that one occasion, they ate their favorite food and they happen to get this huge glucose spike and they never eat it again, their life is worse. It might've been a complete aberration.Eric Topol (46:05):I think your practical impact point, it's excellent. And I think one of the, I don't know if you agree, Kevin, but one of the missing links here is we see these glucose spikes in healthy people, not just pre-diabetic, but people with no evidence of glucose dysregulation. And we don't know, they could be up to 180, 200, they could be prolonged. We don't know if the health significance of that, and I guess someday we'll learn about it. Right?Kevin Hall (46:36):Well, I mean that's the one nice thing is that now that we have these devices to measure these things, we can start to make these correlations. We can start to do real science to say, what a lot of people now presume is the case that these spikes can't be good for you. They must lead to increased risk of diabetes. It's certainly a plausible hypothesis, but that's what it is. We actually need good data to actually analyze that. And at least that's now on the table.Eric Topol (47:04):I think you're absolutely right on that. Well, Kevin, this has been a fun discussion. You've been just a great leader in nutrition science. I hope you'll keep up your momentum because it's pretty profound and I think we touched on a lot of the uncertainties. Is there anything that I didn't ask you that you wish I did?Kevin Hall (47:23):I mean, we could go on for hours, I'm sure, Eric, but this has been a fascinating conversation. I really appreciate your interest. Thank you.Eric Topol (47:30):Alright, well keep up the great stuff. We'll be following all your work in the years ahead, and thanks for joining us on Ground Truths today.**************************************Footnote, Stay Tuned: Julia Belluz and Kevin Hall have a book coming out next September titled “WHY WE EAT? Thank you for reading, listening and subscribing to Ground Truths.If you found this fun and informative please share it!All content on Ground Truths—its newsletters, analyses, and podcasts, are free, open-access.Paid subscriptions are voluntary. All proceeds from them go to support Scripps Research. Many thanks to those who have contributed—they have greatly helped fund our summer internship programs for the past two years. I welcome all comments from paid subscribers and will do my best to respond to them and any questions.Thanks to my producer Jessica Nguyen and to Sinjun Balabanoff for audio and video support at Scripps Research.Note on Mass Exodus from X/twitter:Many of you have abandoned the X platform for reasons that I fully understand. While I intend to continue to post there because of its reach to the biomedical community, I will post anything material here in the Notes section of Ground Truths on a daily basis and cover important topics in the newsletter/analyses. You can also find my posts at Bluesky: @erictopol.bsky.social, which is emerging as an outstanding platform for sharing life science. Get full access to Ground Truths at erictopol.substack.com/subscribe

Fresh from their discussion of La mujer murcielago/The Batwoman (René Cardona, 1968), Chris and Alex are once again joined by Dr Iain Robert Smith, Senior Lecturer in Film Studies at King's College London, to undertake a 10-minute introduction to cult and cult cinema. Listen as the trio offer a closer look at the politics of ‘cult' as a critical and cultural category; what it means to negotiate obsessive reception and fandom in the analysis of film, and the extent to which cult operates as a type of cinema; the oppositional quality of cult and its uneven relationship to the mainstream; the implied gender politics of the so-called ‘masculinity of cult' and questions of inclusion and exclusion; and the enjoyment of both studying and taking part in the kinds of participatory cultures that have shaped the global canon of cult. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

Recorded March 31, 2024 And we're back! After a (not so) short hiatus, Nate and Ryan resume their antics with a discussion of what makes a game, bread point inflation, and musical theatre. Then after judging Flan KitKats and sparkling juice, they turn their attention to the theatre. All this leads up to their main media discussion of the Sir Terry Pratchett novel Wyrd Sisters, where they talk about plot structure, breaking rules, and how to transplant a country. Connect with us Become a member: myhilltodieon.com/members Email: myhilltodieon@gmail.com Reddit: r/MyHillToDieOn Mastodon: @myhilltodieon@mastodon.social Instagram: @myhilltodieon Threads: @myhilltodieon X: @myhilltodieon Bread and Synologys Yamazaki Bread Campaign History Synology DS423 Taste of Japan Nectar Sparkling White Peach and Strawberry Caramel Pudding KitKat Pick 2: Theatrical Plays Nate: Cinderella - Wikipedia Ryan: Les Misérables - Wikipedia Nate: Two from Galilee - Wikipedia (book the musical is based on) Ryan: 1776 - Wikipedia Wyrd Sisters Discworld wiki entry for Equal Rites (has a table listing/explaining the references) Amazon.com Amazon.co.jp Audible 61: Rite to be a Wizard (our episode about Equal Rites) Theme by Michael AD https://soundcloud.com/michael-ad/the-deep-end used with permission

The Fantasy/Animation podcast takes listeners on a journey through the intersection between fantasy cinema and the medium of animation. Available via Apple Podcasts, Spotify and many of your favourite podcast hosting platforms! The Fantasy/Animation Footnotes return with this reflection on the star voice as both an industrial trend within contemporary animation production and as an object of critique often assumed to nothing more than novelty leaned on too heavily to ‘sell' animation as an entertainment medium. Chris takes the lead for this discussion of the potency and power of star sound, with topics including the longstanding history of star voicework across popular animated film and television, and the forceful emergence of the celebrity voice within the landscape of 1990s animation; the authenticating properties of the star and their possible function as a legitimising force; questions of labour and the relationship between the star and the trained voice artist; and how animators can tap into a star persona through character design to enhance or subvert their otherwise hidden vocal presence. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

HolaWe were planning a video on this weekend's Spanish football, but it did not feel right in light of the devastation caused by the floods in Valencia.If you want to donate, LALIGA is supporting the Red Cross in the emergency caused by the DANA. click this link This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit revistadelaliga.substack.com

The Fantasy/Animation Footnotes continue with this latest examination of the many ‘rhetorics' of fantasy that account for the mechanics by which fantasy writers can and do achieve their fantastical effects. Drawn from Farah Mendlesohn's influential work on fantasy literature Rhetorics of Fantasy (2008), this Footnote has Alex reflect on the categorisation of fantasy and the value of Mendlesohn's self-declared “tour around the skeletons and exoskeletons of the genre” to distinguish and divide kinds of storytelling practices; the distinctions between intrusive, immersive, portal quest, and liminal fantasy stories, and what these modes mean for narrative structure, world-building, rules, and characterisation; the disruptions that fantasy makes to a world that is ‘already known' and the game it plays with our assumptions of mimetic fiction; and the way that Mendlesohn's typology of fantasy illuminates both the way that the genre's stories are told and the address that these narratives make to the spectator. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

The Fantasy/Animation Footnotes return with this consideration of the many relationships that cinema can have with - and to - the city. Building on their recent episode on Ratatouille (Brad Bird, 2007), Chris and Alex reflect on those scholars who have placed cinema in dialogue with issues related to space, urban design, and sociology, and who ask questions about how a city is represented onscreen, how its spaces are organised and mapped, and the stakes of re-animating a ‘real' space to transform an otherwise authentic and accessible locale. Topics include how cities can and do become different through their rendition via animation and fantasy; cinephilic cinema cultures that unfold within urban spaces; filmmaking as a form of tourism and the spectacle of the touristic gaze; and the fictionalising of real cities to create an imagined and imaginary place. **Fantasy/Animation theme tune composed by Francisca Araujo** **As featured on Feedspot's 25 Best London Education Podcasts**

Introducing a new style of episode on the Restore To Explore Podcast: 'FOOTNOTES'. These shorter episodes, brought to you by Jim, Mac, Nick, and Tom, will delve into specific concepts and conditions to help educate you on common causes and rehab methods based on the latest research. 'FOOTNOTES' are concise, actionable insights taken from our original longer-form episodes, designed to enhance your understanding of foot health and empower you with the knowledge to take better care of your feet. To listen to the full original episode, please head to the link below. Check out our YouTube channel Here: Find A Health Professional Near You - TFC Pro Directory TFC Helpful Links: Free Training Explorer Membership Free Ebook (The Guide To Foot Freedom) Shop TFC tools and training (Use the code R2E10 to save 10%) Become A TFC Athlete Natural Footwear Finder Fountain - Earn money while you listen to our podcast Follow us: Instagram TikTok YouTube Facebook Music:Love Frequency - Roze Sound

OA1069   Matt is doing a bit of blending of work and pleasure today, by sharing with everyone his footnote fetish. Let's all make this a safe place for Matt to share his more controversial proclivities. Joining us is the author of the book in the episode title, Peter Charles Hoffer. Professor Hoffer is Distinguished Research Professor of History at the University of Georgia. Unlike the justices, Professor Hoffer is an actual historian. Listen and find out not only the fascinating footnote history, but also yet more reasons why originalism and "history and tradition" are not good ways for untrained amateur historians like Samuel Alito to do jurisprudence. If you'd like to support the show (and lose the ads!), please pledge at patreon.com/law!

When the draft majority decision in Dobbs v. Jackson Women's Health was leaked, the media, public officials, and scholars focused on the overturning of Roe v. Wade. They noted Justice Alito's strident tone and radical use of originalism to eliminate constitutional protection for reproductive rights. My guest today has written a book that asks us to also notice over 140 footnotes in the majority opinion and dissent. Are these notes part of the law? In his new book, The Supreme Court Footnote: A Surprising History (NYU Press, 2024), Dr. Peter Charles Hoffer insists that these notes are significant. The footnotes reveal the justices' beliefs about the Constitution's essence, highlight their controversial reasoning, and expose “vastly different interpretations of the role of Supreme Court Justice.” Using a comprehensive qualitative analysis, The Supreme Court Footnote, offers a history of the evolution of footnotes in US Supreme Court opinions and a thoughtful set of case studies to reveal the particular ways that the footnote has affected Supreme Court decisions. Hoffer argues that justices alter the course of history through their decisions and the footnote is the way in which they push their own understanding of the Constitution. Eight case studies show how the footnote has evolved over time. He begins with Chisholm v. Georgia in 1792 and ends with Dobbs v. Jackson case in 2022. Using Dred Scott, Viterbo v. Friedlander, Muller v. Oregon, United States v. Carolene Products, Brown v. Board of Education of Topeka, and District of Columbia v. Heller, Hoffer demonstrates how the footnotes reflect the changing role of the Supreme Court justice and the manner in which they interpret the Constitution. Dr. Hoffer looks back in order to look forward. He offers a study of the footnote that is relevant to contemporary debates over the Supreme Court, methods of interpretation, and politics.  Dr. Peter Charles Hoffer is Distinguished Research Professor of History at the University of Georgia. Hoffer went to University of Rochester and Harvard and has taught at Ohio State, Notre Dame, and UGA (since 1978). He has written books on the Supreme Court, the Federal Court System, infanticide, impeachment, abortion, early American history, slave rebellions, and historical methods. During the podcast, we mentioned: Anthony Grafton's The Footnote: A Curious History (Harvard, 1999) My NBN conversation with Laura F. Edward's on her book (The People and their Peace), originalism and domestic violence The University of Kansas's Landmark Law Series Peter's book Reading Law Forward: The Making of a Democratic Jurisprudence from John Marshall to Stephen G. Breyer (University of Kansas, 2023) The June 2024 recording of Justices Roberts and Alito on godliness Susan's “Sensitive Places?: How Gender Unmasks the Myth of Originalism in District of Columbia v. Heller” (Polity, 2021) Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

This week, we have our first Footnote to the Revised Introduction to Japanese history, expanding on questions we didn't get to touch on during the main series. This week, our question is: what do we know about the origins and practice of early Japanese religion, and how does it relate to what we call Shinto today? Show notes here.  

Lawfare Executive Editor Natalie Orpett sat down with Editor-in-Chief Benjamin Wittes and Legal Fellow Anna Bower to discuss their recent Lawfare article, “What's Going On in Footnote 3?” The article looks at a very specific issue buried in the Supreme Court's recent decision in Trump v. United States, or “the presidential immunity case”: what evidence the prosecution can use—and what it can't—to prove its case. Natalie, Ben, and Anna talked about what footnote 3 says, the many questions it raises, and what it all means for the future of Special Counsel Jack Smith's Jan. 6 case against Donald Trump. To receive ad-free podcasts, become a Lawfare Material Supporter at www.patreon.com/lawfare. You can also support Lawfare by making a one-time donation at https://givebutter.com/c/trumptrials.Support this show http://supporter.acast.com/lawfare. Hosted on Acast. See acast.com/privacy for more information.