Podcast appearances and mentions of Rudolph E Tanzi

Today we have Dr. Rudolph E. Tanzi, who is perhaps best known for co-discovering all three familial early-onset Alzheimer's disease genes. In addition, Rudy's lab was the first to use human stem cells to create three-dimensional human brain organoids and three-dimensional neural-glial culture models of Alzheimer's disease, which became known as “Alzheimer's-in-a-Dish.” These models were the first to recapitulate all three of the key pathological hallmarks of Alzheimer's disease and have made drug screenings faster and cheaper. Rudy is the director of the Genetics and Aging Research Unit as well as the director of the Henry and Allison McCance Center for Brain Health. Rudy is also co-Director of the Massachusetts General Institute for Neurodegenerative Disease at Massachusetts General Hospital and serves as the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Rudy has published more than 700 research papers and is one of the top 50 most cited neuroscientists in the world. He is author of “Decoding Darkness,” and a co-author of two books with Deepak Chopra, “Super Brain” and “The Healing Self.” Show notes: [00:03:18] Ken opens the interview mentioning that Rudy began playing the accordion when he was just seven years old. Ken goes on to ask Rudy about the time his father gave him a Jimmy Smith album and some advice. [00:05:51] Ken mentions that, in addition to Rudy's musical talents, he was also interested in science growing up. Ken asks about Rudy's participation in the Westinghouse Science Talent Search and what that experience was like. [00:07:09] Ken asks Rudy about growing up in Cranston, Road Island. [00:08:39] Rudy talks about how he ended up at the University of Rochester after high school. [00:09:51] Ken mentions that both Rudy's grandfather and father passed away at the age of 45. Ken asks Rudy if this played a role in his pursuit of a career in genetics research. [00:10:57] Rudy explains how he chose Harvard Medical School for his Ph.D. [00:12:47] Ken pivots to ask Rudy about his time working with Jim Gusella in the early 80's at Mass General, where they were the first to ever find a disease gene. Family studies at the time had shown that the Huntington's disease gene was linked to a polymorphic DNA marker. Rudy talks about this discovery and how the chromosomal localization of the Huntington's disease gene was the first step in using recombinant DNA technology to identify the primary genetic defect in this disorder. [00:16:07] Ken asks Rudy about his work in 1987, when he discovered the first Alzheimer's gene, recombinant DNA technology, which causes the production of amyloid. Ken goes on to explain that mutations in the APP gene can cause a rare form of early onset Alzheimer's. Rudy talks about the paper that came out in “Science” that detailed this discovery. [00:18:38] Rudy discusses his personal philosophy and approach to research. [00:19:43] Ken mentions that in Rudy's book, Decoding Darkness, he writes that few nightmares on Earth can compare to Alzheimer's disease. Ken asks Rudy to talk more about this book. [00:21:50] Ken explains that in the same way our physical capabilities will suffer some form of decline with age, it is also expected that we have some decline in memory and cognitive ability as we age as well. However, Ken goes on to say that when people begin to experience age-related memory lapses, it can lead to a lot of anxiety about their genetic predisposition to Alzheimer's. Ken asks Rudy to talk about the lifestyle factors that play into whether someone predisposed to develop Alzheimer's can stave off or avoid disease development. [00:26:09] Ken explains that aging appears to intensify when people stop challenging themselves with new things. Given this, Ken asks Rudy what his thoughts are on challenging our brains as they age to protect our cognitive abilities. [00:29:08] Ken asks Rudy about the principal advances in...

Bienvenido a este espacio, tu podcast: ¡Superando la diabetes!    Este episodio sirve de continuación del E #40, Aléjate del Estrés y a pesar de que vuelvo sobre el tema, es necesario que escuches lo que aquí revelo.   Por supuesto, que si estás en Apple podcast o Spotify te pediré tu valoración de cinco estrellas para llegar a más y más personas. Que déjame decirte, estoy muy complacida con las reproducciones que han dado todos ustedes. Si algo de lo que comparto es de valor para Ti, ¡compártelo! a tus familiares y amigos.   Mi nombre es Mabel, este episodio es para tener cerca lápiz y papel, una vez más te invito: ¡Quédate hasta el final del episodio y entérate cómo nos podemos ir…por encima del diagnóstico!   Bien, pues siguiendo el hilo conductor y los threads están de moda, lo saben; Solamente quiero mencionar algunos aspectos que significan que te adaptas al estrés, y lo acumulas; son aspectos que puedes estar viviendo desde temprana edad, yo puedo decir que desde mis 20's hasta mis 40's los experimenté con bastante frecuencia. Y encontrarlos detallados en un libro, como si hubieran escrito sobre mi propia vida sin conocerme; no me hace mas que concluir, que definitivamente no viví esos años de la forma más sana, aun cuando me sentía realizada en lo profesional, realizada como madre y esposa, en lo profundo, me adaptaba al estrés. Yo viví feliz, mientras tenía una posición destacada como asistente de un supervisor en mi empresa, tenían admiración por mí, me valoraban. Me sentí siempre una super mamá, llevé a mis hijos a deportes, clases de música, estuve con ellos en sus actividades del colegio. Mantuve una relación estable con mi esposo y también pensaba que las situaciones que surgían, eran comunes en otros entornos familiares y que seguramente, habría relaciones, o personas mucho peor, o más cargadas de lo que yo me sentía. ¿Me sigues? Te compartiré aquí la lista, y si estás reflejado en algún aspecto de ella, debes evaluar cómo modificar ahora, hacer ajustes para mantenerte sano porque el daño es invisible a lo largo del tiempo. Esta lista describe un estilo de vida “normal” (entre comillas), estilo de vida que bloquea una vida sana. Y me reveló, lo que tanto sospechaba. 1.La autoestima es construida sobre normas externas, de que si te graduaste, o fuiste ascendido o eres competitivo. 2.La vida vivida en la superficie por prestar tanta atención a lo externo. 3.Las necesidades emocionales son puestas en un segundo plano y no se enfrentan. 4.Las relaciones se instalan en la rutina y los hábitos. 5.Se presta poca o ninguna atención a síntomas de estrés crónico (como te conté en el episodio anterior, un ataque de pánico, o puede ser falta de apetito, de sueño, trastornos intestinales, etc.) 6.Disminución de la actividad física y el contacto con la naturaleza. 7.No hay visión amplia de posibilidades, gracias a las cargas de demandas y deberes constantes de la familia y el trabajo. Te envuelves tanto, que no ves nada a tu alrededor. 8.Se atienden la salud cuando aparecen los síntomas. Todo eso representa un problema mas grande de lo que supones, porque estás dando valores positivos a aspectos que son en realidad negativos. Como te mencioné, a lo largo de ese tiempo que no cuidaste de ti, que no sacaste espacios para detenerte, para priorizar lo que tiene valor; lo que sucedió fue que el estrés creó un daño invisible en la vida que llevas ahora. Pero ojo, no todo está perdido, estás consciente ahora y puedes, a través de recursos profesionales, actividad física, alimentación adecuada y meditación…, recuperarte y mucho. Estoy consciente de que no todo el que me escucha tiene mas de 40 años. Si soy sincera, comencé a engancharme al estrés desde antes de los 25, así que, si eres de veintitantos, mejor aún. Toma nota y aléjate de los provocadores del estrés que para muestra con un botón basta. ¿Te parece? Y es que, a todos, el estrés tiende a afectar tanto las emociones y la conducta, como físicamente. Para irnos por encima del diagnóstico, arranca con todo lo que ya sabes, y por supuesto hay mas recomendaciones: *lee un libro *distráete positivamente, dándote un masaje, yendo a un restaurante *sostén una conversación con alguien que te importa, de al menos media hora *si te sientes en una situación demasiado indignante, que te molesta, sal del lugar, reprograma la cita o evento siempre que se pueda. Lo importante es no dar espacio a la preocupación, a la queja o al pesimismo…ahí es que te fuiste por encima del estrés. Sabes que me puedes contactar por IG en www.instagram.com/hola.vidaenpositivo Envíame tu comentario, temas de interés y dime desde que país me escuchas, me encantará saludarte. Si es por YouTube, igualmente, suscríbete y comenta. Estoy feliz y agradecida de contar con tu fiel sintonía, no te puedes perder los próximos episodios porque como siempre, nos vamos por encima del diagnóstico. ¡Claro que sí!   Libro de referencia: Sánate a Ti Mismo de Deepak Chopra y Rudolph E. Tanzi https://amzn.to/3NPyEL7              

¡Superando la diabetes! Este episodio es para compartirlo a tus familiares y amigos, Dale por WhatsApp, o por mensaje, ¡Te lo agradecerán! En el libro, Sánate a Ti Mismo, que he reseñado en este podcast, varias veces, confirmé que no puedes mejorar tu vida con dieta y ejercicios mientras vives de forma demandante y acelerada. ¡Ea rayos! Entonces, ¿por qué insistir tanto en lo primero? Insisto en una mejor alimentación y en la actividad física porque desde mi experiencia, alimentarte de forma correcta y hacer actividad física recurrentemente, te evitará muchos problemas adicionales con tu diagnóstico. Cuando sé que no estoy haciendo uno, enfatizo en lo otro. Y en mis mejores semanas estoy activa en ambos. Ahora bien, he aprendido a bajarle 2 rayas a vivir de forma demandante: te voy a dar un ejemplo mío, precisamente con este podcast: Quiero grabar con frecuencia, quiero que sea un excelente recurso para Ti, quiero que a través de mis errores y aciertos veas reflejada tu experiencia con el diagnóstico, con la vida con diabetes, con la vida misma. Y al principio tenía como exigencia personal grabar una vez por semana. La primera semana que no pude hacerlo, me ocupó mucho la mente, “haber fallado” y luego, entiendo yo que a través de lo poco que hago de meditación, llegué a la serenidad de decirme: el podcast lo grabarás cada vez que puedas hacerlo, Mabel Simplemente, me quité esa presión. Me ocupo del podcast con compromiso, está en mi agenda, pero sin la presión de que tiene que ser obligatoriamente una vez por semana.       La otra parte: ¿Quién hoy, no vive de forma acelerada? Entonces imagínate Tu; si vivir en estrés es la norma hoy día, ya con eso, todas tus células se ven afectadas. ¿No crees que será bueno contrarrestar ese impacto del estrés, haciendo ejercicios y alimentándote mejor? Estoy segura de que sí, de que es de gran ayuda, lo he vivido y se lo he escuchado decir a médicos en incontables ocasiones. Otro punto es que, definitivamente, también hay que buscar la forma de encontrar cómo apartarnos de los provocadores del estrés. Hace más de una década, sufrí un ataque de pánico mientras esperaba mi turno en la oficina de un cardiólogo. No sabía que me estaba pasando y era mi primera vez allí. Te podrás imaginar el susto que me di, o bien si te ha sucedido, sabes que lo primero que uno piensa ante un ataque de pánico, es que le está dando un ataque, precisamente, pero del corazón. Yo sentí como se aceleraba todo mi organismo, como si mi cuerpo fuera un automóvil estacionado, en neutro y le estuvieran acelerando al máximo. Nada agradable, por cierto. Y ahora no recuerdo si fue en ese instante o luego, que tuve el pensamiento de que ese tipo de eventos, me traería consecuencias. Abiertamente te digo que me ha costado mucho, manejar el estrés; principalmente el estrés permanente, ese que activa supremamente el cortisol en tu cuerpo. Es por eso que desde que descubrí que puedo tomar el control, me he dedicado a enfrentar el estrés acumulado y a prepararme con conciencia plena o mindfulness para prevenir el impacto de los nuevos eventos en la vida. Apenas como principiante en la materia, ya llevo unos años sintiéndome mejor. Dicen los autores del libro que: soportar el estrés o adaptarse a él son malas estrategias, hay que despejarlo y prevenir el impacto de los nuevos eventos para que no sean demasiado severos. La respuesta de tu sistema completo al estrés crónico es enfermarse. Desde Ya, busca la forma de desconectarte del estresor, Yo lo he trabajado, buscando apoyo emocional y con mi mejor arma, la meditación. Te invito a que dejes de adaptarte al estrés, adaptarse es bueno, en algunas circunstancias, pero con el estrés, no es suficiente. En las notas del episodio, te dejaré el enlace del libro que he usado como referencia. Gracias por estar del otro lado, acompañándome. Puedes seguirme por IG en www.instagram.com/hola.vidaenpositivo y escribirme por mensaje directo sobre tu experiencia. Me encantará saludarte. ¿Nos vamos por encima del diagnóstico? ¡Claro que sí!   Libro: Sánate a Ti Mismo de Deepak Chopra y Rudolph E. Tanzi https://amzn.to/3NPyEL7

It is a common belief that memory and brain function decline as years go by, but what if our lifestyle and choices could change how we age and even improve our brains? Harvard Medical School professor Rudolph E. Tanzi is one of the world's foremost experts on the causes of Alzheimer's. He has written a series of books with bestselling author and physician Deepak Chopra. We explore one in the series titled "Super Brain." A manual for relating to the brain in a revolutionary new way, Super Brain shows us how to use our "three-pound universe" as a gateway for achieving health, happiness, and spiritual growth. Super Brain dismantles the five most widespread myths about the brain that limit your potential and shows us how to... Use our brain instead of letting it use us -Create the ideal lifestyle for a healthy brain -Reduce the risks of aging -Promote happiness and well-being through the mind-body connection -Access the enlightened brain, the gateway to freedom and bliss -Overcome the most common challenges, such as memory loss, depression, anxiety, and obesity Our brain is capable of incredible healing and constant reshaping. Through a new relationship with our brains, we can transform our lives.

Dr. Tanzi is the Vice-Chair of Neurology, Director of the Genetics and Aging Research Unit, Co-Director of the Henry and Allison McCance Center for Brain Health, and Co-Director of the MassGeneral Institute for Neurodegenerative Disease at Massachusetts General Hospital. He also serves as the Joseph P. and Rose F. Kennedy Professor of Neurology at Harvard Medical School. Dr. Tanzi received his B.S. (microbiology) and B.A. (history) at the University of Rochester in 1980 and his Ph.D. (neurobiology) at Harvard Medical School in 1990. Dr. Tanzi was a key member of the teams that discovered the first Alzheimer's disease (AD) gene, the amyloid precursor protein (APP) gene, and the two other early-onset familial AD genes, presenilin 1 and presenilin 2. As leader of the Cure Alzheimer's Fund Alzheimer's Genome Project, Dr. Tanzi identified several other AD genes, including CD33, the first AD gene shown to regulate neuroinflammation in AD. He also discovered the Wilson's disease gene and several other neurological disease genes. Dr. Tanzi's team was the first to use human stem cells to create three-dimensional mini human brain organoids of AD, dubbed “Alzheimer's-in-a-Dish”. This model was the first to recapitulate all three key AD pathological hallmarks. He and his team have successfully used these organoids to screen for approved drugs and natural products that can stop AD brain pathology. Dr. Tanzi has developed several novel therapies for AD including gamma secretase modulators targeting amyloid pathology (Phase 1 planned 2021) and AMX0035, which was already successful in a clinical trial of ALS and now under priority review for approval at the FDA. Dr. Tanzi also discovered that beta-amyloid plays a functional role in the brain as an anti-microbial peptide, supporting a potential role for infection in the etiology of AD. Dr. Tanzi serves as Chair of the Cure Alzheimer's Fund Research Leadership Group and on numerous scientific advisory and editorial boards. He has published over 600 research papers and is one of the top 50 most cited neuroscientists in the world. He has received the highest awards in his field, including the Metropolitan Life Foundation Award, Potamkin Prize, Ronald Reagan Award, Oneness in Humanity Award, Silver Innovator Award, the Smithsonian American Ingenuity Award, the Brain Research Foundation Award, and the Kary Mullis Award for Medical Research. He has also been named to TIME magazine's list of TIME100 Most Influential People in the World. Dr. Tanzi is also a New York Times bestselling author, who has co-authored the books Decoding Darkness, and bestsellers, Super Brain, Super Genes, and The Healing Self. Dr. Tanzi joins us to mark The One Way Ticket Show's 10th anniversary for our special series--a “one way ticket to optimal mental, physical and spiritual well-being”. On this episode of the program, Dr. Tanzi's conversation with Host Steven Shalowitz includes why today is rapidly becoming the golden age for solving age related brain diseases, lifestyle changes we can make to reduce the risk of Alzheimer's and questions around the brain-consciousness connection. Dr. Tanzi is just one of the engaging personalities featured on The One Way Ticket Show. During the regular season of the program, Host Steven Shalowitz explores with his guests where they would go if given a one way ticket, no coming back. Their destinations may be in the past, present, future, real, imaginary or a state of mind. Steven's guests have included: Nobel Peace Prize Winner, President Jose Ramos-Horta; Legendary Talk Show Host, Dick Cavett; Law Professor, Alan Dershowitz; Fashion Expert, Tim Gunn; Broadcast Legend, Charles Osgood; International Rescue Committee President & CEO, David Miliband; Former Senator, Joe Lieberman; Playwright, David Henry Hwang; Journalist-Humorist-Actor, Mo Rocca; SkyBridge Capital Founder & Co-Managing Partner, Anthony Scaramucci; Abercrombie & Kent Founder, Geoffrey Kent; Travel Expert, Pauline Frommer, as well as leading photographers, artists, chefs, writers, intellectuals, etc.

"What's stronger than reality? Knowing that you are the reality maker." - Deepak Chopra & Rudolph E. Tanzi from their book "Super Brain."How crazy AND empowering is it to know that you create your reality?www.allyoumama.comIG -@MeghanQBarrett

El maestro y autor bestseller Deepak Chopra descubre los secretos para superar nuestras limitaciones y acceder a un campo de posibilidades infinitas. ¿Cómo lo conseguimos?Convirtiéndonos en metahumanos. Ser metahumanos significa vencer las construcciones de la mente que subyacen bajo la ansiedad, la atención y el ego, y entrar en un nuevo estado de conciencia en el que deliberadamente tenemos experiencias clave que pueden transformar la vida desde lo más profundo. No se trata sólo de mindfulness o meditación, sino de despertar: expandir nuestra conciencia hacia todo lo que pensamos, decimos y hacemos, con el fin de darle sentido a la vida. Para hacer posible esta práctica, Chopra culmina el libro con una guía de 31 días para convertirnos en metahumanos.Una vez que despertamos -dice-, la vida se transforma porque la conciencia plena amanece en nuestras vidas. Sólo entonces se manifiesta nuestro potencial infinito.«En su nuevo y brillante libro, Deepak Chopra argumenta con éxito que la conciencia es la única creadora del ser, la mente, el cerebro, el cuerpo y el universo como lo conocemos. Después Deepak nos enseña que cuando comprendemos verdaderamente esta idea revolucionaria, serán removidos de forma efectiva los sistemas de pensamiento limitante y la negatividad que nos impiden alcanzar nuestro máximo potencial humano. ¡Sumamente recomendable!» -Dr. Rudolph E. Tanzi, profesor de Neurología en la Escuela de Medicina de Harvard, y coautor de los bestsellers El yo sanador, Supercerebro y Supergenes«¡Metahumano es una poderosa llamada para despertar! Al fusionar brillantemente conocimientos científicos y holísticos, Deepak Chopra nos permite ir más allá de los constructos mentales ilusorios para atestiguar la realidad sin límites. ¡Sólo así podremos alcanzar nuestro potencial total!» -Dr. Lars Buttler, cofundador y ceo de la Artificial Intelligence Foundation«Al integrar descubrimientos recientes de neurociencia, endocrinología y psicología, Deepak Chopra demuestra en términos concretos cómo las restricciones reduccionistas y materialistas de la naturaleza humana son simplemente incorrectas y limitan seriamente a aquellos que las sostienen. Este libro es un parteaguas.» -Allan Leslie Combs, PhD, profesor de Estudios de la Conciencia en el Instituto de Estudios Integrales de California«En Metahumano, Deepak Chopra nos brinda una guía paso a paso para volver a imaginar la realidad del mundo en que vivimos, una realidad que no está limitada por las creencias y entendimiento que tenemos sobre el mundo material y físico, sino por lo ilimitado de nuestra intención y energía.» -Robert LoCascio, fundador y ceo de LivePerson See acast.com/privacy for privacy and opt-out information.

Register for my 2020 Virtual Mental Health Solutions Summit here:https://www.drleafconference.com **Early bird tickets end October 15 **Pre-order my new mental self-care tips book here for less 20%: https://drleaf.com/collections/all/products/101-ways-to-be-less-stressed Sign up to join my free text program and receive mental health care tips and strategies, exclusive offers and more! Just text DRLEAF to 1(833) 285 3747 (*Only available for U.S numbers at this time) When we think of genes, we tend to think about the genes we do have and the ones we don’t have, not the genes we can change. But the truth is that we have a lot of control over our genetic activity. Yes, some genes we cannot do much about, but the vast majority of our DNA listens to us: our thoughts, choices and behavior. In this podcast I speak with Harvard professor, neuroscientist and researcher Dr. Rudolph E. Tanzi, one of Time Magazine’s 100 most influential people and founder of the field of neurogenetics, about the influence we have over our genetic activity, how our lifestyle impacts our wellbeing on the level of our DNA, how to keep our brains and bodies young and healthy, the relationship between spirituality and science, the power of mindful thinking, and so much more! Read the blog here: https://drleaf.com/blogs/news/how-to-use-your-thoughts-to-influence-your-gene-expression-for-now-and-future-generations-the-five-most-widespread-myths-about-the-brain-that-may-be-limiting-your-potential-with-dr-rudolph-tanzi For more info on Dr. Tanzi and to get his books visit: https://www.madrc.org/members/10924 ***Special offers from our sponsors*** -Ritual (my favorite multivitamin! And they have options for men too!): To get 10% off your first three months of Ritual multivitamins see: https://ritual.com/drleaf -Thrive Market (where I do all my online grocery shopping + they have the best clean skincare products!): try Thrive Market today and become a member risk-free! Go to thrivemarket.com/DRLEAF. Join today and you’ll get up to $20 in shopping credit toward your first order! Podcast Highlights 4:45 The importance of deep thinking to learn and understand 10:00 The close relationship between science and spirituality 22:33 Genes, epigenetics and how we can control our DNA expression 29:00 Why what we think today can affect future generations 36:29 How our lifestyle choices can prevent Alzheimer’s and cognitive decline 56:00 Why learning is about brain connectivity, not brain activity Additional Resources: -Get my new brain detox app SWITCH on sale now! Get 50% off a 3 month subscription. Just look for Switch on Your Brain in the App Store or Google Play or visit: https://theswitch.app -Visit my website at https://drleaf.com for more free resources, tips, and tools to help you improve and heal your mental health! Follow me on social media for daily mental self-care tips! -Instagram: @drcarolineleaf: https://www.instagram.com/drcarolineleaf/ -Facebook: Dr. Caroline Leaf: https://www.facebook.com/drleaf -Twitter: @drcarolineleaf: https://twitter.com/DrCarolineLeaf -Youtube: https://www.youtube.com/drcarolineleaf If you enjoyed this episode please leave a 5 review on iTunes, Google Play, or wherever you are listening! And don't forget to subscribe and share this podcast with friends and family! I love seeing your posts on social media! --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

TU ESTILO DE VIDA DETERMINA TU ESTADO DE SALUD; PARA APROVECHAR TU PODER DE AUTO-CURACIÓN DEBES FORTALECER TU SISTEMA INMUNE CON HÁBITOS MÁS SALUDABLES Y NATURALES Esta idea sobre Efectividad Extraordinaria fue extraída de "The Healing Self" por Deepak Chopra y Rudolph E. Tanzi. Este título contiene un plan de cambio de una semana para fortalecer el sistema inmune y ralentizar el proceso de envejecimiento. Recomendamos todas las ideas de este libro a cualquier persona que sufra alguna enfermedad degenerativa y a líderes con la necesidad de aumentar el bienestar y la salud de los miembros de su equipo. Para dialogar ¿Qué cambios positivos te gustaría hacer en tu estilo de vida? ¿Qué es lo primero que debes hacer para conseguir tal cambio? ¿Te sirvió esta idea? Propágala para que más personas descubran de dónde vienen las buenas ideas. Suscríbete en ideasinfalibles.com o visita ideasinfalibles.com/premium para conseguir resúmenes completos.

We're getting you ready for your mind and body goals in 2019, with our guest celebrity trainer Alec Penix. Alec is the author of a brand new health and fitness book called Seven Sundays. It is a guided 43-day program that focuses on food, sleep, exercise, and spirituality. We also discuss Alec's love of Self-Help Books, reading to learn, and some tips to get you through the holidays. Everything we talk about on today's episode can be found below in the show notes. The Stacks participates in affiliate programs, and shopping through the links below (mostly Amazon) helps support the show, at no cost to you. Books Seven Sundays by Alec PenixAwaken the Giant Within by Tony RobbinsThe Four Agreements by Don Miguel RuizSuper Brain by Rudolph E. Tanzi Ph.D. and Deepak Chopra M.D. Psycho-Cybernetics by Maxwell MaltzA Return to Love by Marianne Williams The 5 Love Languages by Gary ChapmanSeven Sundays (on Audible)It by Stephen KingThe Holy Bible (King James Version)Fifty Shades of Grey by E. L. JamesFifty Shades of Grey (Universal Pictures)Anna Karenina by Leo TolstoySteph KingJohn GrishamThe Pelican Brief by John GrishamHamlet by William ShakespeareHamlet (Warner Bros.)The Giver by Lois LowryNapoleon HillThe Maker's Diet by Jordan RubinNutrient Timing by John Ivy Everything Else The Stacks Book Club Battle of the Books 2018The Stacks InstagramBig Time RushBy The Book (The New York Times)Simon and Schuster Connect with Alec: Alec's Instagram|Alec's Twitter|Alec's Facebook Connect with The Stacks: Instagram|The Stacks Website|Facebook|Twitter|Subscribe|Patreon|Goodreads|Traci's Instagram To contribute to The Stacks, join The Stacks Pack, and get exclusive perks, check out our Patreon page. We are beyond grateful for anything you're able to give to support the production of this show. If you prefer to do a one time contribution go to paypal.me/thestackspod. Sponsors Audible- to get your FREE audiobook download and FREE 30 day trial go to audibletrial.com/thestacks. My Mentor Book Club - for 50% off your first month of new nonfiction from My Mentor Book Club go to mymentorbookclub.com/thestacks The Stacks participates in affiliate programs. We receive a small commission when products are purchased through links on this website, and this comes at no cost to you. Shopping through these links helps support the show, but does not effect opinions on books and products. For more information click here.

Deepak Chopra, M.D is the author of more than 80 books translated in over 43 languages, including 22 New York Times bestsellers. His latest book, coauthored with Dr. Rudolph E. Tanzi, is Super Genes. Trained in internal medicine and endocrinology, he is the founder of the Chopra Center for Wellbeing outside San Diego, an adjunct professor of Executive Programs at the Kellogg School of Management at Northwestern University and a Distinguished Executive Scholar at Columbia University Business School. He is known worldwide as an eloquent interpreter of the philosophies and spiritual practices birthed in his native India. We spoke about his new book, the gap between spirituality and science, and the work of the Chopra Foundation. Learn more about Deepak Chopra here: http://www.chopra.com/bios/deepak-chopra%2C-m.d

Kari hangs out with go-to, real-food dietitian, Serena Marie, RD, and physical therapist and yoga teacher, Joanne Ambrogi to gab about March's Book Club book Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being. Runner of the Week, Kelly Martin, shares her experience running with her dog, Mya. Want in on a little secret? We've found the modern-day manual of how to live! Are you stuck with your genetic destiny and you think there's nothing you can do about it? Or do you think we “manipulate” our genes through particular lifestyles to change our destiny? On the show today, we share what the March Book Club book means to us. Here are some helpful links: Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being by Deepak Chopra, MD, and Rudolph E. Tanzi PhD Go Wild: Free Your Body and Mind from the Afflictions of Civilization by Dr. John Ratey TRLS Episode 123: “Seven Ways To Take Control Of Your Health” TRLS Episode 53: “John Ratey” Super Mind: How to Boost Performance and Live a Richer and Happier Life through Transcendental Meditation by Norman E. Rosenthal, MD A Year to Live: How to Live This Year as If It Were Your Last by Stephen Levine Better Than Before: What I Learned About Making and Breaking Habits--to Sleep More, Quit Sugar, Procrastinate Less, and Generally Build a Happier Life by Gretchen Rubin TRLS Episode 64: “The Power of Habit and the Need To Believe”   Super Talk: March Book Club Want in on a little secret? We've found the modern-day manual of how to live! Are you stuck with your genetic destiny and there's nothing you can do about it? Or can you “manipulate” your genes through particular lifestyles to change your fate? Kari, Serena, and Joanne talk about March's Book Club featured pick, Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being. Serena explains what the terms “radical well-being,” “epigenetics,” and “microbium” mean. The main concept of the book is how genes are not hard wired. In essence, the DNA that we get from our parents sets up the blueprint of how we'll look, what diseases we may get one day, and so on, Years ago, doctors thought that the cards you got dealt were the cards you had, so to speak. But Super Genes defies this notion. Kari notes that the book states that your DNA accounts for only 5 percent of what could happen to you. Joanne points out that some people will say, “Oh, I can't do anything about it, because my [fill in family member] had [fill in disease], so now I'm destined to have it.” She feels that this book brings about an awareness where it's very empowering if you choose to take the book's message. The books gives you ways to take the message and put it into practical life. Kari loves that the book emphasizes choice. Go Wild: Free Your Body and Mind from the Afflictions of Civilization by Dr. John Ratey mentions inflammation, as does Super Genes. We know about diet, and Serena has talked about anti-inflammatory diets, since running causes inflammation in our bodies. (Listen to Episode 123: “Seven Ways To Take Control Of Your Health” and Episode 53: “John Ratey” as examples of this.) Kari thought that the cornerstones in Super Genes were diet, stress, meditation, sleep, and emotions were especially interesting, because they are very similar to Dr. John Ratey's six keys to living a healthier lifestyle. Serena' favorite part of the book that threw her of her feet was how the authors mention that psychosocial dwarfism is real. Joanne piggybacks off of Serena's comments about psychosocial dwarfism in how real it is to keep your stress levels down while pregnant. Joanne points out that you really are the one to determine what the advice will do for you. Having the wherewithal to understand what we don't understand means needing to slowing down. The book talks about one of the activities that you really need to do—meditation/yoga. Kari found the different meditation styles very interesting, because it relates to the June Book Club book, Super Mind: How to Boost Performance and Live a Richer and Happier Life through Transcendental Meditation by Norman E. Rosenthal, MD. Joanne talks about what helps her sleep and what yogendra is. Kari mentions that the book talks about things that are going on that we think help us, but really don't, like multitasking Kari's greatest takeaway is the word “success.” Success is such a powerful word, but “well-being” isn't as much. How about defining success as living your life well? Kari talks about A Year to Live: How to Live This Year as If It Were Your Last by Stephen Levine. Joanne would want folks to know that it takes courage to look at your life and to truly sit back and act as if this was the last year of your life. How much of your time did you spend sitting down watching TV or on the computer, for example? Kari mentions a woman named Allison who practices ayurvedic medicine who works with Joanne. Joanne wasn't surprised at all that Super Genes talks about it. The book talks about how you think determines what types of exercise you choose, what types of foods you eat, and so on, and to balance that is something that most people don't really think about. Kari mentions the four types of people from Better Than Before: What I Learned About Making and Breaking Habits--to Sleep More, Quit Sugar, Procrastinate Less, and Generally Build a Happier Life by Gretchen Rubin. Be aware of your life, and what you think is so key. The book is reader-friendly, and it lays out what you can do if you want to live well. Take one thing at a time, and it's very realistic. Serena likes how the book shows how powerful the holistic mindset is. The placebo effect and mindset are powerful. She loved reading the science to why that is true. Joanne thinks that the book gives you practical applications to things, and it meets people at different levels depending on what you're trying to gain by reading the book. Listen to Episode 64: “The Power of Habit and the Need To Believe.” To give feedback or ask questions, connect with Kari on Twitter, Facebook, or via e-mail! Runner of the Week: Kelly Martin Canadian resident Kelly joins Kari, along with her dog, Mia, who is a sheepadoodle, to chat about how it is to run with Mia and why she chose the particular breed. Kari references Episode 127: “How To Run With And Away From Dogs With Veterinarian Ernie Ward.” She tells Kari that working breeds make good running dogs. She started running with Mia when Mia was two years old. Dogs' bones can be fully grown before you can run with them. She runs with Mia six days a week at around a nine-minute mile pace. Pick the right dog. When talking to breeders or a rescue facility, make sure the dog is a high-energy dog. She's been running for about ten years, and her advice is to just keep going. The hardest part is the first kilometer (or mile). Kari mentions that TRLS Action for Healthy Kids teammates Foti and Todd both run with their dogs. Gratitude Jar (Woot! Woot!) Joanne is grateful to be able to look outside and see the sun and the breeze. She felt rich gratitude. Serena is grateful for her family in New Jersey. She's grateful that so many of her family and friends live on the Jersey Shore and that she has a true feeling of being wrapped in the most wonderful nostalgia and being on the water. She's so grateful that she can relive beautiful memories of her childhood. Kari is grateful for Super Genes and to be able to talk to Serena and Joanne about it—to be able to look at the information and to ask what they think. Next week, Kari interviews Norman E. Rosenthal, MD, who wrote Super Mind: How to Boost Performance and Live a Richer and Happier Life through Transcendental Meditation. Contact: Joanne Ambrogi: Facebook Page Ambrogihealth@yahoo.com   Kelly Martin: Website: PromotionalBridge.com Email: kelly@promotionalbridge.com Facebook: /promotionalbridge   Serena Marie, RD: Website: www.SerenaMarieRD.com Facebook: /SerenaMarieRD Twitter: @SerenaMarieRD Instagram: SerenaMarieRD   Kari Gormley: Facebook: The Running Lifestyle Show Twitter: @KariGormley Instagram: @KariGormley

Kari interviews friend, Featured Guest, and Runner of the Week, Rebecca Clark, with whom she ran the 2012 Marine Corps Marathon (first marathons for each). Kari and Rebecca share how they trained for this marathon amidst full-time jobs, family life, and friendship. Go-to, real-food dietitian, Serena Marie, RD, shares her tip on what to do when you overbuy fruits and veggies. Featured Guest and Runner of the Week: Rebecca Clark Rebecca Clark explains how she trained for her first marathon with two kids (now she has five), while working full-time as an attorney and still spending quality time with her husband. She also chats about how her life has changed since then. Rebecca shares why she chose to run the 2012 Marine Corps Marathon (MCM) with the Runner's World Challenge (now called Runner's World VIP). She explains how she transitioned from being an indoor treadmill runner at the gym to running outside. Rebecca ran her first 5K in March 2011, and she was hooked! She ran 5Ks and completed the 2011 Philadelphia Half Marathon. Next, she wanted to find a marathon that kept her motivated and moving forward. Her boss suggested the MCM. Rebecca explains why she still loves treadmill running, along with using the elliptical. She chats about how she got outside of her comfort zone and faced her challenges, like creating her own private law practice. She shares what she told herself to go outside in run versus the typical, “Oh I should probably clean the house. Oh, but the kids need me.” Rebecca was able to build her own schedule, having a private practice, but she explains how she tackled long runs on the weekend. She explains how she didn't want her family to begrudge her long weekend runs and how she made the thought of the marathon exciting. Rebecca tells what she took away from the Runner's World Kari and Rebecca recount the MCM experience and how they wanted to beat the 5:30 pacers. Kari talks about some key moments that happened along the course, like seeing Joe Taricani from The Marathon Show around Mile 3. Rebecca tells listeners what happened in 2014 that made her not run the Bank of America Chicago Marathon. She chats about her total loss of identity and how she was physically and emotionally drained and how she got back to her “me time.” Rebecca talks about an overuse injury in her left knee once she got back to running. Kari and Rebecca talk about the post-race MCM party and the post-race “waddle.” They talk about the gift of running, how it changes you, and how it will hopefully always be there for you. Rebecca plans to run the Philadelphia Half Marathon on Saturday, November 19, 2016. The marathon is on Sunday, November 20. Kari wants to run the half marathon, but might run the Rothman Institute 8K on November 19 instead (she's listening to her body and not her mind). There will be a TRLS meetup on Saturday, November 19. Mark your calendars, and more details to come! Kari sings the praises of the Galloway Method versus the Couch to 5K Serena Marie, RD Serena Marie, RD, offers a tip on what to do with extra fruits or vegetables when you get a little overzealous at her local farmer's market. Serena buys large freezer bags and puts green, leafy vegetables and fruits in them to freeze to use for green smoothies. She adds half coconut water, half regular water in her smoothies. Her favorite is cucumber, celery, spinach or kale, and a whole lemon. Check out Serena's blog post titled, “Eight Tips to Eat More Veggies” for a recipe. For more of a dessert-type smoothie, try unsweetened coconut milk, unsweetened almond milk, or yogurt with water and ice. Kari suggests that having a green smoothie with some protein in the morning would make a good breakfast. Serena mentions organic cheese sticks. Let us know what your tips and tricks are! Gratitude Jar (Woot! Woot!) Kari is grateful for her son's favorite YouTube channel so that she could record with Serena. Serena is grateful for her local farmer's market. She loves cherries, and tart cherries (or juice) are anti-inflammatory. Anything (like kale, spinach, or beets) that contain nitric oxide may help runners feel less fatigued (when you eat these foods on a regular basis) due to the vasodilation. Next week, Kari, Serena Marie, RD, and Joanne Ambrogi (from Episode 64: “The Power of Habit and the Need to Believe”) talk about the March Book Club book, Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being by Deepak Chopra MD, and Rudolph E. Tanzi, PhD. Please remember to leave a TRLS review on iTunes! Here's how: Launch Apple's Podcast app. Tap the Search tab. Enter the name of the podcast you want to rate or review. Tap the blue Search key at the bottom right. Tap the album art for the podcast. Tap the Reviews tab. Tap Write a Review at the bottom. Write your review! Connect with us on Twitter, Facebook, or via e-mail! Contact: Rebecca Clark: Email: raclarkesq@gmail.com   Serena Marie, RD: Website: www.SerenaMarieRD.com Facebook: /SerenaMarieRD Twitter: @SerenaMarieRD Instagram: SerenaMarieRD   Kari Gormley: Facebook: The Running Lifestyle Show Twitter: @KariGormley Instagram: @KariGormley

Dr. John Ratey, expert on the correlation between brain activity and how it's important for us to move our bodies, discusses seven ways to take control of your life, along with the link between depression and sugar, being responsible for our own well-being, and the benefits of exercise. Serena Marie, RD, talks about foods that are great for brain health. Featured Guest: Dr. John Ratey Harvard psychiatrist and foremost authority when it comes to the brain and exercise, Dr. John Ratey, discusses the correlation between sugar and depression/other diseases, being proponents for our own well-being, and the benefits of exercise. He has been on TRLS in such episodes as “John Ratey” (Episode 53), “Dr. John Ratey” (Episode 59), “Optimize Your Brain With Dr. John Ratey, Part 1” (Episode 74), and “Optimize Your Brain With Dr. John Ratey, Part 2” (Episode 75). Companies work with people to find better ways to accommodate health in their lives, like startups working with the elderly to get them moving and to get them out into the community more. We're near a tipping point; people recognize that we have to be more responsible for ourselves and our own health. We're empowered by Google medicine and also knowing how to be healthier and how to increase our well-being. The biggest thing that Kari read recently is that our genes account for 5% of what can happen to us (from Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being by Deepak Chopra, MD, and Rudolph E. Tanzi, PhD). Our genetic inheritance can guide us to that wisdom that's impacted in our genes—to be in the moment, to eat right, to get the proper amount of sleep, to connect with others, and so on. He's excited about two different Silicon Valley firms that he's working with who recognize that small tribes are the way to promote a better sense of well-being. He'll be talking with an artificial intelligence group and another group that has proven that successful entrepreneurs have a passion for taking steps in helping the elderly try to improve their lives and getting them connected with others through exercise and the community. If you have been following him on Facebook, you'll know that he's recently been interviewed by Larry King, and to his surprise a group in CA put together a song called “Ratey-O-Active” on YouTube (like “Radioactive”). The “Super Seven” Commandments include eating right, being outside, being with your tribe, meditation, getting enough sleep, exercise, and mindset. Question: Can you get the same tribe feeling from a Facebook group that you can from meeting in person? Answer: It can be a starting point, but it's never going to be the same. But there are a lot of different mechanisms being developed and that are already in existence (like Meetup). He talks about the November Project and walking or running up and down the stairs at Harvard Stadium. The “dopamine squirt”—the surprise or novelty of an e-mail Using our past history and our biometrics (blood pressure, pulse) as well as what we've felt and what we like in the past is called affective computing so that we can be guided to prompt ourselves to move—it increases your state of well-being. You do not need sugar if you are burning fat. Dick Manning is a trail runner in Montana who has eliminated sugar for years from his diet. He's lost weight and gotten out of depression. He is using fat as his fuel (via a ketogenic diet). High concentrations of sugar lead to inflammation and putting on weight/fat. Ratey cautions jumping on the probiotics bandwagon (meaning purchasing probiotics in pill form rather than eating foods with probiotics) because we know very little about it. We're on the cusp of learning. Serena Marie, RD, talked about probiotics on “The Hottest “Living A Running Lifestyle” Trends With Kalyn Rozanski” (Episode 118). The first prescription for someone who has gastrointestinal problems is to eliminate sugar from his or her diet. For an injured runner, try to avoid depression by doing things like upper-body aerobics (Conductorcise), boxing, kettlebells, use the elliptical, or some alternative to staying active. Exhaust yourself other ways; when you do that you are raising your heart rate. Kari has been getting in the pool to do aqua running while dealing with her back injury. He mentions a New York Times article called “Learning a New Sport May Be Good for the Brain” written by Gretchen Reynolds. It helps grow your brain. He now starts off his lectures talking about neuroplasticity. That means putting ourselves in a state where the brain cells are the most liable to grow and change. The more depressed/stressed you get, the less plastic your brain gets—the less it's able to grow and respond to the environment. When it comes to sleep, during the stage of early sleep at night is when you're more liable to get into restorative sleep where your brain and your body get the best kind of sleep. It's the early morning where we get into REM sleep. In the late morning is when we dream the most, and that's very important. In Go Wild, Ratey talks about Dr. Beverly Tatumn of Spelman College (President from 2002–2015). She shut off her e-mail at 9 p.m. to prepare herself to go to sleep by 10:30 or 11 a.m. so that she could get eight hours of sleep. She helped Spelman College put an emphasis on students' health and fitness. When you go to some gyms/health clubs in northern California for an entire year, you actually get your money back/can go for free! Ratey's latest book is in process! He and Dr. Hallowell are doing an update to Driven to Distraction: Recognizing and Coping with Attention Deficit Disorder from Childhood Through Adulthood. Dr. Ratey is also doing an update to Spark: The Revolutionary New Science of Exercise and the Brain. Exercise and Parkinson's—people are raising money for boot camps for recently diagnosed patients that will help to prevent the onslaught of the condition. Norman Doidge recently wrote a book called The Brain's Way of Healing: Remarkable Discoveries and Recoveries from the Frontiers of Neuroplasticity Itself, and he talks about “walking off” Parkinson's disease. When we exercise, we change the chemistry of our brains and our bodies. Serena Marie, RD Go-to, real-food dietitian, Serena Marie, RD, talks about fat and sugar as related to brain health. Serena talks about omega-3 fatty acids--which are anti-inflammatory, polyunsaturated fatty acids that are most bountiful in fatty fish (salmon, sardines, anchovies, tuna), in seaweed, and in nuts and seeds (macadamia and walnuts). Grass-fed meat is another good source of omega-3s. The version of omega-3 fatty acids that you receive from meat is very bioavailable. When we're getting it from nuts, seeds (chia or hemp seeds), the conversion is very low, so it's harder to get the appropriate amount from a diet void of fish. Aim for 1,000 milligrams a day or so. Over half of the brain's weight is made of fat. To keep our brains healthy, we need to be eating the thing that they're comprised of. Our brain is made of DHA. Studies show that having DHA intake during your lifetime is going to help with cognition. It's shown and correlated with having better memory and executive function. Studies recommend one to four servings per week. Some research says that DHA helps with depression as well. Insulin is the hormone that your body needs to run through the bloodstream to holla, “Let me in!” to your cells. Studies have shown that those people who are insulin resistant have been associated with a higher risk of Alzheimer's disease. The proposed pathways are complicated, and there isn't one that's well studied or understood. Because insulin is unable to do its job and sugar is hanging out in the blood stream, there's increased oxidation of stress and contributes to deleterious effects in memory. Studies have shown that less than 20 grams of carbohydrates a day is a great way to combat memory problems and dementia. Gratitude Jar (Woot! Woot!) Kari is grateful that integrated health professionals exist, that the science exists and is being talked about, and that people are trying to live healthier lives. Serena is grateful that Siggi's yogurt started making 4% milk fat yogurt. She's obsessed with the strawberry rhubarb flavor (but they also have plain). It has 9 grams of sugar. People with a lactose intolerance can sometimes handle yogurt and hard cheeses. Next week, Kari talks with artist Ann Rea who runs as a form of relaxation and to help her be an even more beautiful artist. And don't forget that on Sunday, April 17, Kari and Dr. Marjorie Dejoie will be at Philadelphia Runner in Center City at 9 a.m. leading a vision board workshop. You'll leave the event with your very own vision board! Contact: John Ratey: Website: JohnRatey.com Facebook: The Ratey Institute Twitter: @jratey   Serena Marie, RD: Website: www.SerenaMarieRD.com Facebook: /SerenaMarieRD Twitter: @SerenaMarieRD Instagram: SerenaMarieRD   Kari Gormley: Facebook: The Running Lifestyle Show Twitter: @KariGormley Instagram: @KariGormley

For decades, we've been taught that genes are FIXED AND UNCHANGEABLE. Not so, say New York Times bestselling authors Deepak Chopra and Rudolph E. Tanzi. “It's time to explode such rigid notions” writes co-author Tanzi. On todays show Tanzi will tell everyone the news – that “gene activity is largely under our control.” “TIME 100 Most Influential People in the World,” Harvard Professor and acclaimed reseracher, Tanzi will share his insights on how lifestyle choices make a dramatic impact on optimizing your health and behavior by more than 95%. Join our show today to learn how to unlock the “Astomishishing Power of Your DNA for Optimum Health and Well-Being.”

Deepak Chopra is a pioneer of integrative medicine and the author of more than 80 books published in 43 languages. Many have been New York Times best-sellers in both the fiction and nonfiction categories. Rudolph E. Tanzi is an internationally acclaimed expert on Alzheimer's disease and was included in TIME magazine's "TIME 100 Most Influential people in the World." In this episode, Live Happy COO, Co-Founder and Editorial Director Deborah Heisz talks with Deepak and Rudolph on their latest book Super Genes: Unlock the Astonishing Power of Your DNA for Optimum Health and Well-Being.

For the first time, researchers have been able to replicate Alzheimer's outside of the brain – they're calling it "Alzheimer's in a Dish." This advancement will allow scientists and doctors to evaluate their experimental treatments and techniques that – until now – would have required human subjects for testing. This could speed up the research process and help us find a way to stop Alzheimer's faster. We're thrilled to have the head of that groundbreaking team, Dr. Rudolph E. Tanzi of Boston's Massachusetts General Hospital, on this Alzheimer's Talks.Support the show (https://www.usagainstalzheimers.org/ways-donate)

Rev. Jim Lee, the Senior Minister at Renaissance Unity in Warren, MI joins Annette Rochelle Aben for this segment of InTouch Interviews to share the energy and events that make this church a truly spirit-centered place.  Events such as Renaissance Unity welcoming Deepak Chopra, Tuesday, Nov. 27th for a lecture and book signing and energy like being able to participate in Holiday Community Outreach. So thank you for tuning in as Rev. Jim Lee encourages us to embrace Unity for the holiday season and beyond.  www.renaissanceunity.org