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Discover why hormones are off and what's really driving the imbalance. In this episode, we break down five root causes — from gut dysfunction and disrupted sleep to chronic stress, appetite dysregulation, and omega-3 deficiency — and walk through what you can actually do to fix it. FEATURED PRODUCT Berberine is a powerful botanical compound that acts as a natural GLP-1 supporter — the same metabolic pathway targeted by medications like Ozempic — helping regulate blood sugar, reduce insulin resistance, and restore appetite signaling from the gut. Since metabolic hormones like insulin and leptin are the first to derail your entire hormone cascade, Berberine directly addresses one of the deepest root causes discussed in this episode. It also supports gut microbiome diversity, making it a foundational tool for anyone working to reclaim hormonal balance naturally.
This is a practical conversation on circadian living — how to structure your day around light, darkness, food, movement and sleep in a way that supports your biology. We also explore the modern mismatch of indoor LED lighting, artificial light at night, late eating, phone use before bed, blue blockers, beeswax candles, incandescent light, night driving, flicker, skin cancer nuance, sun exposure, DHA, omega-3s and the deeper philosophical implications of living in rhythm with nature. CONSULT DR MAX
A new Alzheimer's study linked omega-3 fish oil (EPA & DHA) supplement use to faster cognitive decline, but the real story is far more nuanced than the headlines suggest.In this discussion, cardiologist Dr. Bret Scher breaks down the study and explains why the quality, freshness, and source of omega-3s may matter more than most people realize.The study used data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and found that omega-3 supplement users experienced greater cognitive decline over five years compared to non-users. But the details matter:The study did not assess supplement quality, oxidation, dosage, or dietary habitsOxidized fish oil may behave very differently from high-quality DHA and EPAWhole food omega-3 sources like salmon, sardines, and mackerel consistently show different outcomes in researchLifestyle factors like sleep, exercise, stress, and metabolic health remain critical for brain healthOne of the biggest takeaways: supplements are not interchangeable with whole foods. And no supplement can replace the foundation of metabolic health, including nutrition, movement, sleep, stress management, and social connection.
Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember
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In this episode, Dr. Jockers breaks down the five nutrient deficiencies most closely linked to memory loss, brain fog, and Alzheimer's disease. You'll learn why these deficiencies are more common than most people realize and how they can impact cognitive health long before a diagnosis occurs. You'll discover the warning signs of low magnesium, vitamin D, and vitamin B12, along with the role each nutrient plays in supporting healthy brain function. The conversation also explores key lab markers that may reveal hidden deficiencies affecting memory, mood, and focus. You'll also learn how folate and vitamin B6 influence neurotransmitters, inflammation, and long-term cognitive health. Plus, you'll hear practical strategies for identifying nutrient gaps and supporting your brain through targeted nutrition and lifestyle changes. In This Episode: 00:00 B12 Aging Warning 00:16 Podcast Welcome 04:18 Top Deficiencies Overview 05:33 Magnesium Brain Calm 08:43 Magnesium Labs And Fixes 14:02 Vitamin D, Mood And Labs 18:40 B12 Dementia Mimic 23:20 B12 Causes And Absorption 27:19 B12 Labs Foods Supplements 31:40 Folate Dementia Risk 37:45 Folate Supplements MTHFR 39:04 Vitamin B6 Neurotransmitters 41:54 B6 Labs Foods Dosing 43:46 Wrap Up And Next Steps If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday. If you're feeling wired, tired, and depleted, it's time to replenish your electrolytes with Relyte from Redmond. Made with Redmond's Real Salt, this clean formula provides essential electrolytes like sodium, potassium, and magnesium without any sugar or artificial ingredients. Perfect for those under stress, fasting, or living an active lifestyle, Relyte helps restore hydration, improve energy, and support mental clarity. Visit RedmondLife.com/DrJockers and use code JOCKERS for 15% off today! Support your heart, brain, and immune system with Paleovalley's Wild Caught Fish Roe, a whole food source rich in Omega-3s like EPA and DHA. It's more bioavailable and stable than traditional fish oil, offering benefits for cardiovascular health, mood, and brain function. Go to paleovalley.com/jockers for 15% off your order! Support your gut-hormone balance and curb cravings naturally with Wonder Biotics, a clinically proven, doctor-formulated probiotic featuring Bifidobacterium B420. Feel less bloating and reduce cravings within 3–6 months. Save 10% using code DRJOCKERS10 at wonderbiotics.com "Red light therapy on the thyroid for 10 minutes a day helped nearly 75% of women reduce or stop their thyroid meds." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off at RedmondLife.com/DrJockers using code JOCKERS. Save 15% at Paleovalley.com/Jockers with code JOCKERS. Save 10% using code DRJOCKERS10 at wonderbiotics.com Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Well-known as the leader of the carnivore diet, Dr. Anthony Chaffee – medical doctor and neurosurgical expert joins Trending with Timmerie. Episode Guide Gut health and carnivore (1:11) Does the type of meat you consume matter? (18:57) I’m low on DHA. What should I do? (22:15) Recommendations for getting enough protein (24:38) Why would I need protein shakes? (35:09) Is beef better than pork? (38:19) How do you eat more protein when meat is expensive? (41:34) Cholesterol? (49:30) Resources mentioned: Previous shows with Dr. Anthony Chaffee: https://relevantradio.com/?cat=23210&s=chaffee Dr. Chaffee www.dranthonychaffee.com Harvard study on Carnivore/Ketosis and depression https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2022.951376/full Dr. Chaffee’s social media: @anthony_chaffee Food Resources: Ayoba Droewors https://ayobafoods.com/collections/bundles
In this episode, Nicolle W. Davis, PhD, RN, SCRN, FAHA, Director of the Mobile Stroke Program at UF Health, and Janice Walker, DHA, MBA-HCM, NEA-BC, BSN, RN, System Nursing Officer and Senior Vice President at UF Health, join the podcast to discuss the development of stroke protocols and the growth of innovative mobile stroke programs. They share how bringing specialized stroke care directly to patients can improve outcomes, reduce treatment delays, and strengthen coordinated care across the health system.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Tom Dayspring is a world-renowned lipidologist and one of the most thoughtful teachers in the field of lipid metabolism. In this episode, Tom returns to The Drive for a deep dive into the relationship between lipids and brain health, beginning with the fundamentals of cholesterol transport before exploring why the brain's cholesterol system operates almost entirely independently from the rest of the body. Tom examines the roles of apoB, apoA-I, and especially apoE in cholesterol homeostasis, discusses how APOE genotype influences Alzheimer's disease risk, and unpacks the complex links between cholesterol metabolism, amyloid, and tau pathology. He also reviews what is currently known—and still uncertain—about the effects of statins, ezetimibe, omega-3 fatty acids, and emerging CETP inhibitors on brain health and neurodegenerative disease risk. Although highly technical, this conversation provides an essential framework for understanding the nuanced relationship between lipid-lowering therapies, cardiovascular disease prevention, and neurodegenerative diseases in an area often clouded by misinformation. We discuss: The fundamentals of cholesterol transport in the body, and how peripheral cholesterol metabolism differs from cholesterol handling in the brain [2:45]; How cholesterol is transported through plasma and stored within cells, and why lowering LDL cholesterol does not deplete the body or brain of cholesterol [11:45]; How apoB particles drive atherosclerosis, why lowering lipids matters, and the factors that influence individual cardiovascular risk [20:00]; How the brain produces and transports its own cholesterol using apoE lipoproteins independently of circulating cholesterol and apoB-containing lipoproteins [29:00]; How apoB structure influences LDL receptor binding and LDL clearance [39:00]; How neurons acquire cholesterol from apoE-containing lipoproteins and why desmosterol serves as a unique marker of cholesterol synthesis in the brain [41:45]; The difference between the APOE gene and the apoE protein, the major APOE genotypes found in humans, and how APOE4 influences Alzheimer's disease risk [48:45]; HDL function beyond cholesterol: immune function, protein cargo, and communication with the brain [53:30]; How APOE4-associated defects in brain cholesterol transport may promote Alzheimer's disease: amyloid production, neuronal cholesterol homeostasis, and cholesterol clearance [58:00]; Statins and brain health: reviewing the evidence of the potential impact of statins on cognition and Alzheimer's disease risk [1:09:00]; Desmosterol and 24S-hydroxycholesterol as biomarkers of brain cholesterol metabolism and statin effects [1:17:15]; Possible cognitive benefits of ezetimibe beyond lowering apoB [1:19:30]; EPA, DHA, and the evidence for omega-3 fatty acids in brain health [1:23:15]; Obicetrapib: an emerging CETP inhibitor with potential implications for both cardiovascular and brain health [1:31:00]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
The “Enhanced Games”, with no-holds-barred performance-enhancing drugs, yields scant advantages over “clean” contests; Does saturated fat increase insulin resistance? Can a heart attack victim avoid statin use with CoQ10? Omega-3 fish oil shows promise vs. type 2 diabetes; Motorized e-scooter use needs to be regulated NOW!
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Krill oil's unique benefits In this episode of Live Foreverish, hosts Dr. Mike and Dr. Crystal welcome Dr. Maria Tinta, Director of R&D at Acre Bio Marine, to discuss krill oil's emerging role in weight loss and muscle preservation. Dr. Maria explains krill oil's unique composition—omega-3s (EPA and DHA), choline, and astaxanthin delivered in phospholipid form—which enhances bioavailability. She also highlights the emerging benefits of krill oil for your health and fitness journey! #LELEARN #EDULFsocial Guest Bio: Dr. Maria Tinta is a pharmacist by training and did a PhD on Molecular Biotechnology at the University of Barcelona (Spain). After a short experience in the pharma industry, she devoted the last 10 years to research and development in the nutrition space, working with several ingredients such as biotics, enzymes, polyphenols, and more recently, lipids. She has authored several scientific publications and patents, and coordinated more than 20 clinical studies with nutraceuticals.
There is a 45% chance the fish oil sitting in your cabinet right now is already oxidized. And rancid omega-3s do not just fail to help you. Research shows they generate pro-inflammatory byproducts that work against everything you are taking fish oil for. Dr. G breaks down exactly how this happens, how to test what is in your cabinet tonight with zero equipment, and what to actually look for before you buy another bottle. In this episode, you will learn: • The two oxidation markers most brands count on you never knowing about, the peroxide value and the anisidin value, and the total oxidation score that tells you whether your fish oil is actually fresh • Why the number on the front of your fish oil bottle is not the amount of omega-3s you are getting, and the simple math that reveals whether you have been underdosing for years • The at-home test you can do right now with one capsule, a pin, and 30 seconds that will tell you immediately whether to keep your fish oil or throw it away Plus the specific brands that passed Dr. G's independent investigation for certificate of analysis standards, packaging, storage, meaningful EPA and DHA doses, and proper oxidation scores. Timestamps: 0:00 - Intro 1:00 - The George Washington University Study That Exposed What's on Shelves 1:46 - Peroxide Value, Anisidine Value & the TOTOX Score Explained 2:18 - Why Fish Oil Is One of the Most Chemically Fragile Supplements You Can Buy 3:10 - What Legitimate Brands Do to Protect Their Oil (And What to Look For) 3:39 - The Label Scam: 1,000mg of Fish Oil Is Not 1,000mg of Omega-3s 4:24 - What a Clinically Meaningful Dose of EPA and DHA Actually Looks Like 5:09 - Three Questions to Ask Any Fish Oil Brand Before You Buy 7:00 - How to Test the Fish Oil in Your Cabinet Right Now 8:08 - The Brands That Passed Dr. G's Investigation Learn more about your ad choices. Visit megaphone.fm/adchoices
What if the health of your food starts long before it reaches your plate? In this episode of the ReThink Health Podcast, Dr. Eric Berg and I explore the fascinating connection between soil health, regenerative farming, nutrient density, metabolic health, and the ketogenic diet. Dr. Berg shares his personal journey from being a self-described "junk food junkie" struggling with severe health issues… to discovering low-carb nutrition, healthy keto, and the powerful role food quality plays in long-term wellness. But this conversation goes far beyond keto. We dive deep into the modern food system, why regenerative farming may produce more nutrient-dense meat, how soil microbes influence plant and animal health, and why the quality of the food you eat may matter just as much as the macros. You'll learn: Why Dr. Berg says going vegan was "the sickest time" of his life Why bioavailable nutrients like vitamin A, iron, zinc, DHA, and protein may be harder to obtain from plants alone The difference between "healthy keto" and simply eating low carb How soil health may directly influence plant, animal, and human health The hidden problems with conventional agriculture, glyphosate, hormones, antibiotics, and grain-fed livestock What Dr. Berg's regenerative beef testing revealed about omega-3s, inflammation markers, phytonutrients, and metabolic health How keto and intermittent fasting may support weight loss, mood, energy, blood sugar, and metabolic health If you've ever wondered how modern food production affects human health, this episode offers a thought-provoking look at the connection between agriculture, metabolism, and wellness. VALUABLE RESOURCES Paleovalley Bone Broth Protein >>> Support whole-body repair with clean, glycine-rich protein from 100% grass fed bone broth. Save up to 20% today on Paleovalley Bone Broth Protein. Dr. Eric Berg is a doctor of chiropractic, natural health educator, bestselling author, and one of the most widely recognized voices in ketogenic nutrition and intermittent fasting. After struggling with his own health issues in early adulthood, Dr. Berg became deeply interested in nutrition, metabolism, insulin resistance, and holistic health. Over the last several decades, he has educated millions of people on topics including keto, fasting, metabolic health, nutrient density, hormones, gut health, and regenerative agriculture. Dr. Berg is also a regenerative farmer who studies the relationship between soil biology, food quality, and human health. His work explores how farming practices may influence nutrient density, inflammation, microbiome diversity, and chronic disease risk. Through his books, educational content, and massively popular YouTube channel, Dr. Berg has helped millions better understand the connection between food, metabolism, and overall wellness. THANKS FOR LISTENING! Thanks so much for joining us this week! Have feedback or a question? Email us at support@paleovalley.com. We'd love to hear from you! If you enjoyed this episode, please share it with someone who might benefit from the information. Following the ReThink Health Podcast on YouTube, Spotify, or iTunes helps us reach more people who need to hear this and keeps you updated on new episodes. Likes, subscribes, ratings, and reviews are incredibly helpful and deeply appreciated… we read every single one! Let's spread this knowledge and help others together. See you next time! Click below to follow on YouTube, Spotify or iTunes: Don't miss the podcast… Vegan Diet Nearly Destroyed My Health – Here's What I Eat Now (that's healed 10,000+) with Dr. Eric Berg. In this episode, Dr. Eric Berg explores how soil health and regenerative farming affect our food… and what that could mean for inflammation, metabolism, energy, and long-term health. >>> Support whole-body repair with clean, glycine-rich protein from 100% grass fed bone broth. Save up to 20% today on Paleovalley Bone Broth Protein.
Dr. Carole Keim sits down with neurologist and Mama Bird founder Dr. Mika Gupta for an insightful conversation about baby brain development and the critical role nutrition plays from preconception through early childhood. As both a physician and a mom, Dr. Gupta draws on personal experience and explains the concept of the “first 1,000 days”. She explains why this window is so important for building a strong foundation for a child's lifelong brain health. Together, Dr. Keim and Dr. Gupta explore how thoughtful nutritional choices can support mom and baby during this period of rapid growth and development. Dr. Gupta and Dr. Keim discuss key nutrients that support brain development, including iron, DHA, choline, iodine, and methylated B vitamins, along with practical guidance on how to meet these needs through diet and supplementation. Dr. Gupta also breaks down common misconceptions about prenatal vitamins. She highlights the importance of ingredient forms like methylfolate and why one supplement may not cover everything. With Dr. Keim's warm and relatable guidance, this episode empowers parents with knowledge to make informed, supportive choices for themselves and their growing babies. Key Moments 00:00 Meet Dr. Mika Gupta and her journey into neurology and nutrition 02:19 What are the “first 1,000 days” and why they matter 03:03 Why prenatal vitamins should start before pregnancy 04:03 Understanding MTHFR and methylated vitamins 06:22 Key nutrients for baby's brain development explained 08:22 Can you get enough nutrients from food alone? 11:26 Nutrition needs during postpartum and breastfeeding 12:48 Common mistakes when choosing prenatal vitamins 16:44 Why one prenatal vitamin isn't enough for everything 18:38 What “brain-first” vitamins mean 23:55 One key takeaway for supporting baby's brain development About Dr. Mika Gupta: Dr. Mika Gupta is a double board-certified neurologist, MIT-trained, and founder of Mama Bird. She's also a mother of two — a daughter training at the Royal Ballet School and a son with Down syndrome — two radically different brains that taught her more about human potential than any textbook ever could. After her son was born, Dr. Gupta stopped trusting a system that was never built for women and started building what should have existed all along: evidence-based tools for brain health during the first 1000 days, the most critical window of development. She's a brain activist — helping women see that the invisible architecture they build and sustain is the most neurologically important work in human life. __ Resources discussed in this episode: The Holistic Mamas Handbook is available on Amazon The Baby Manual is also available on Amazon __ __ Contact Dr. Carole Keim MD Website: CaroleKeim.com Linktree TikTok Instagram Contact Dr. Mika Gupta Website: DrBrainMom.com Website: LoveMamaBird.com Dr. Mika Gupta on LinkedIn Instagram: @drbrainmom ---FullScriptUse this link to get 10% off and free shipping for orders over $50.HIRO DiapersUse code DRCAROLEKEIM for a discount at checkout. Click here. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode, Dr. Jockers sits down with Dr. Josh Axe to explore advanced cellular healing strategies for thyroid, hormones, and metabolism. You'll learn why most thyroid issues aren't caused by the thyroid itself and how targeting the gut, liver, adrenal glands, and mitochondria can reverse hypothyroidism naturally. Discover practical ways to balance hormones, manage menopause and PMS symptoms, and support healthy metabolism with simple lifestyle changes, nutrient strategies, and targeted herbs. Dr. Axe shares insights on mitochondrial health, liver support, and dietary adjustments that make a real difference. We also cover actionable steps to boost energy, curb cravings, and improve vitality through hydration, probiotics, personalized nutrition, and supporting your cellular systems. Listen closely for tips that can transform how your body feels and functions every day. In This Episode: 00:00 Thyroid Root Causes 03:18 Cellular Healing Intro 05:14 Reverse Hypothyroidism 08:37 Warmth Light Therapy 11:24 Mitochondria Support Hacks 17:41 Yogurt Pomegranate Desserts 20:57 Women Hormones Overview 22:27 Menopause Stress Reset 30:20 Menopause Diet Herbs HRT 33:50 Cell Membranes Cancer Link 36:19 Repairing Cells With Fats 36:54 Ditching Seed Oils 38:59 Liver Hormone Connection 40:48 Saturated Fat Nuance 43:42 Personalized Nutrition Plans 45:22 Liver Detox Strategies 46:49 PMS and PCOS Protocols 49:20 Boosting Male Testosterone 54:39 Relationships and Hormones 59:26 Birth Control Thyroid Risks 01:02:05 Longevity Clinic Therapies 01:05:01 Wrap Up and Resources If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday. If you're feeling wired, tired, and depleted, it's time to replenish your electrolytes with Relyte from Redmond. Made with Redmond's Real Salt, this clean formula provides essential electrolytes like sodium, potassium, and magnesium without any sugar or artificial ingredients. Perfect for those under stress, fasting, or living an active lifestyle, Relyte helps restore hydration, improve energy, and support mental clarity. Visit RedmondLife.com/DrJockers and use code JOCKERS for 15% off today! Support your heart, brain, and immune system with Paleovalley's Wild Caught Fish Roe, a whole food source rich in Omega-3s like EPA and DHA. It's more bioavailable and stable than traditional fish oil, offering benefits for cardiovascular health, mood, and brain function. Go to paleovalley.com/jockers for 15% off your order! Upgrade your cooking with 100% grass-fed beef tallow from Kettle & Fire—seed oil-free, high smoke point, and packed with flavor while supporting liver and overall health. For a limited time, get 25% off sitewide, including tallow and bone broth, using code DRJOCKERS at kettleandfire.com/drjockers. Available at select Sprouts, Whole Foods, and Kroger stores nationwide. Support your gut-hormone balance and curb cravings naturally with Wonder Biotics, a clinically proven, doctor-formulated probiotic featuring Bifidobacterium B420. Feel less bloating and reduce cravings within 3–6 months. Save 10% using code DRJOCKERS10 at wonderbiotics.com "Red light therapy on the thyroid for 10 minutes a day helped nearly 75% of women reduce or stop their thyroid meds." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off at RedmondLife.com/DrJockers using code JOCKERS. Save 15% at Paleovalley.com/Jockers with code JOCKERS. Get 25% off sitewide, including tallow and bone broth, using code DRJOCKERS at kettleandfire.com/drjockers Save 10% using code DRJOCKERS10 at wonderbiotics.com Connect with Dr. Josh Axe: Website: https://draxe.com/ Podcast: https://podcasts.apple.com/us/podcast/the-dr-josh-axe-show/id1700689487 Instagram: https://www.instagram.com/drjoshaxe Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
In this episode:• The childhood disease cod liver oil helped reverse• Why Weston A. Price believed modern diets changed facial structure within one generation• The connection between vitamin A, D, K2, DHA, bones, teeth, and babies• Why traditional cultures protected special foods for women before pregnancy• How mouth breathing and jaw development compound over time• Why cod liver oil is not the same thing as regular fish oil• The real lesson behind the “smelly spoonful” our grandparents were told to takeWhat did we remove from the modern diet, and what did it quietly cost us?
In this Mini Mikkiepdia episode, Mikki takes a fresh look at omega-3 fatty acids beyond the usual “good for your heart and brain” message. She explores emerging and lesser-known research on omega-3s and their potential role in protecting muscle during immobilisation, supporting fertility and oocyte quality, reducing period pain, improving submaximal exercise efficiency, and possibly influencing dementia and colorectal polyp risk. Mikki also discusses the difference between marine omega-3s like EPA and DHA, and plant-based ALA, including surprising findings in motor neurone disease research. With practical dosing context, cautions around study limitations, and a reminder to consider omega-3 index testing, this episode is a useful listen for active people, women in perimenopause, athletes, and anyone interested in targeted supplementation. Highlights / Topics Covered: How omega-3s may reduce muscle loss during injury, surgery, or immobilisation The role of EPA and DHA in fertility, period pain, and inflammatory pathways Emerging research on omega-3s, APOE4, dementia risk, and brain structure Why athletes may benefit from improved submaximal heart rate and perceived effort Practical dosing considerations and why the omega-3 index matters Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenNZ listeners - save 10% off Calocurb by using the code Mikkipedia10 at www.calocurb.co.nzSave 20% on all Nuzest Products WORLDWIDE with the code MIKKI at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order
→ Get My Brand Masterlist: https://drchristiangonzalez.com/best-brands-form-2-2/ Episode Description In 2025, researchers published what may be the most important longevity study of the decade. Three years. Over 2,000 participants. A randomized controlled trial. And the results stopped the researchers themselves. A 61% reduction in invasive cancer risk. A 39% reduction in becoming physically frail. And measurable slowing of biological aging, verified by epigenetic clocks, the most sophisticated tool science has for measuring how fast your cells are actually aging. These were not elite athletes. They were regular older adults. And the three things that produced these results are inexpensive, accessible, and available at any supplement store. Most people are either missing them entirely or doing them in a way that produces almost no benefit. Dr. G breaks down exactly what the study found and what you need to do with it. In this episode, you'll learn: • Why omega-3 deficiency carries a mortality risk comparable to smoking, and the specific EPA and DHA dose that the research shows actually slows biological aging at the cellular level • Why vitamin D is not optional if you exercise, and why low vitamin D means the training you are already doing is producing a fraction of the benefit it should • Why the combination of all three produces results that are not additive but multiplicative, and what that means for anyone over 40 who wants to change their biological trajectory The window that matters most is not when you are 60. It is now. Timestamps: 0:00 - Intro 1:38 - Why This Study Deserves Your Attention (And Why No One Is Talking About It) 3:02 - Who This Episode Is For: Men Over 40 and the People Who Love Them 4:45 - The Deficiency Crisis: Most People Are Missing All Three Interventions 6:29 - Thing #1: Why Low Levels Are as Dangerous as Smoking 8:44 - Thing #2: The Pro-Hormone Your Muscles and Immune System Are Waiting For 10:37 - Thing #3: The One Thing That Is Not Optional for Healthy Aging 13:22 - What Happens When You Do All Three Together (The Numbers Are Dramatic) 14:48 - Exactly What to Take, How Much & How Often Learn more about your ad choices. Visit megaphone.fm/adchoices
In this Her Stack series episode, I open up about maternal mental health, postpartum anxiety, and the invisible biological load mothers carry long after the six-week checkup is over. This episode is not just for the newly postpartum mother. It is for the mother whose kids are four, eight, fifteen, and still asking herself why she does not feel like herself. I share why motherhood structurally changes the brain, hormones, and nervous system, and why so many mothers are left feeling anxious, foggy, depleted, or unlike themselves without ever being properly screened or supported. I walk you through the science of the postpartum neurosteroid withdrawal, the gray matter changes that persist for years, and the five-system map underneath maternal brain fog. Then I break down the full four-pillar protocol I use with my one-to-one clients: foundational nutrition, lifestyle and biohacking tools, the supplement layer including some of the most under-discussed compounds for the maternal brain, and the advanced peptide layer including Semax, Selank, NAD+, and bioregulators. This is the episode every mother needs. Send it to one. Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. I TALK ABOUT: 02:00 - My free peptide masterclass for moms next week 04:10 — Why maternal mental health is not just a six-week postpartum issue 06:30 — The numbers every mother should know (and the screening gap that explains everything) 08:20 — How pregnancy structurally changes the brain (Nature Neuroscience, 2017) 11:40 — The neurosteroid withdrawal nobody warned you about, and the FDA's $34,000 drug that proves it is real 13:50 — Pillar 1: DHA, protein, ferritin, blood sugar stability, and methylated Bs for the maternal brain 22:40 — Pillar 2: Protected sleep cycles, morning sunlight, vagal nerve activation, and red light to the brain 28:00 — Yoga nidra and NSDR as the workaround for mothers who cannot engineer a protected sleep cycle 32:45 — Simplifying routines, meals, outfits, and planning to reduce mental load 35:00 — Co-regulation: Why one hour of real adult conversation is medicine 38:40 — Creatine for maternal mental health, depression support, and cognitive fatigue in sleep-deprived moms 40:50 — Saffron and inositol for postpartum mood, anxiety, racing thoughts, and the "can't shut off the brain" symptoms 42:15 — Magnesium L-threonate, glycine, vitamin D, and low-dose methylene blue for sleep, brain fog, mitochondrial support, and nervous system balance 45:25 — Why peptides are an advanced layer and should come after nutrition, lifestyle, and supplement foundations 46:10 — Semax and Selank for anxiety, cortisol support, BDNF, dopamine, brain fog, memory, and maternal brain support 50:00 — NAD+ and bioregulators (Cortagen, Cerluten, Epithalon) for maternal energy, neuronal support, circadian rhythm, melatonin, sleep, and long-term brain health 58:15 — Why postpartum anxiety and depression need different kinds of support, and why SSRIs work for some mothers and not others 1:00:00 — Why lingering symptoms matter and which labs mothers should check RESOURCES: Labs to ask your provider for: TSH, free T3, free T4, reverse T3, ferritin, vitamin D, DHA panel Join The LongHer Life for women-specific guidance on peptides, hormones, and longevity. Free Peptide Masterclass for Moms: Join the waitlist for the next live class. The Her Stack Planner: The first peptide tracking journal built around female biology. Crisis support: 988 in the US, 988 in Canada PRODUCTS MENTIONED: Supplements DHA (omega-3) Creatine monohydrate Saffron (Crocus sativus extract) Inositol (myo + d-chiro blend) Glycine Magnesium L-threonate (BiOptimizers code: BIOHACKINGBRITTANY) Vitamin D Lion's mane mushroom Bacopa monnieri Methylated B vitamins (methylcobalamin, methylfolate, P5P) Methylene blue (low dose, pharmaceutical USP only) Peptides Semax Selank NAD+ options NOVOS code: BIOHACKINGBRITTANY Nuchido TIME+ code: BIOHACKINGBRITTANY Nasal spray (Synchronicity Health code: BIOHACKINGBRITTANY) Bioregulators Cortagen Cerluten Epithalon LET'S CONNECT: Instagram, TikTok, Facebook Shop my favorite health products Listen on Spotify, Apple Podcasts, YouTube Music
Seu paciente chega no consultório com um vidro de ômega-3 importado e te olha esperando confirmação: "é bom pro coração, né, doutor?" Durante décadas, a resposta foi automática. Hoje, ela precisa de mais cuidado, e de evidência.Nesse episódio, Mateus Prata e Raphael Rossi mergulham de cabeça na história do ômega-3 e risco cardiovascular: da expedição dos anos 1970 à Groenlândia até o PISCES, publicado no NEJM em 2025. Um episódio que vai te fazer repensar o que você diz (e prescreve) no consultório.O que você vai aprender:
Send us Fan MailWhat happens when a Harvard-trained psychiatrist follows the evidence beyond traditional medicine?In this episode of MedEvidence, Dr. Michael Koren sits down with Dr. Carol Locke, physician entrepreneur and Chief Science Officer of OmegaBrite, to explore her remarkable journey from psychiatry and academic research at Harvard's McLean Hospital to pioneering evidence-based omega-3 innovation.Dr. Locke shares how clinical research into mood disorders led to surprising discoveries about omega-3 fatty acids, brain health, inflammation, stress response, and emotional resilience. Together, they break down the science behind omega-3 balance, the role of EPA and DHA, third-party testing, and what clinical trials reveal about omega-3 supplementation's impact on mood, anxiety, inflammation, and overall wellness.You'll also hear insights on physician entrepreneurship, innovation in nutraceutical science, and why evidence-based quality matters when choosing supplements.In this episode: How omega-3s influence brain function and mood The link between inflammation, stress, and mental health What clinical trials reveal about omega-3 supplementation Why supplement purity and testing matter Emerging science on omega-3 delivery to the brain Advice for physicians pursuing innovation Be a part of advancing science by participating in clinical research.Have a question for Dr. Koren? Email him at askDrKoren@MedEvidence.comListen on SpotifyListen on Apple PodcastsWatch on YouTubeShare with a friend. Rate, Review, and Subscribe to the MedEvidence! podcast to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramX (Formerly Twitter)LinkedInWant to learn more? Checkout our entire library of podcasts, videos, articles and presentations at www.MedEvidence.comMusic: Storyblocks - Corporate InspiredThank you for listening!
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In this episode, Dr. Jockers sits down with Michael Cohen to explore how neurofeedback can help retrain the brain's "electrical software" to improve anxiety, sleep, focus, and emotional balance. You'll learn why nutrition alone may not fully resolve brain fog or nervous system dysregulation, and how the brain can be trained to create healthier patterns. Michael breaks down how chronic stress, trauma, overstimulation, and poor nervous system regulation can keep the brain stuck in survival mode. You'll discover how different areas of the brain influence mood, attention, overwhelm, and emotional reactivity—and how targeted brain training may help restore balance. You'll also hear powerful stories of transformation involving ADHD, autism, concussion recovery, anxiety, and trauma healing. This conversation dives into the connection between sleep, brain health, emotional resilience, and the tools that may help people finally feel calm, focused, and mentally clear again. In This Episode: 00:00 Neurofeedback Success Story 00:34 Interview Setup and Goals 03:38 Meet Michael Cohen 04:28 Brain Software vs Nutrition 06:18 How Neurofeedback Trains 07:28 Sympathetic Overdrive Explained 10:38 Tools to Reset Calm 12:49 Neurofeedback Process Demo 16:12 Brain Areas and Targets 18:27 Electrodes and Brain Mapping 23:53 Case Study and Root Causes 25:55 Mold EMF and Sleep Tips 27:03 Simple Timer Hack 27:16 NFL Brain Recovery Story 29:45 Concussions and Brain Timing 31:42 Nutrition Plus Neurofeedback 34:33 Beyond Pharmaceuticals 35:41 Autism Case Breakthrough 37:20 Trauma and Lasting Healing 42:54 Finding Neurofeedback Help 44:18 Home Training and New Tools 45:09 Brain Entrainment and Devices 47:27 Wrap Up and Sleep Priority 49:53 Final Thanks and Outro If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday. If you're feeling wired, tired, and depleted, it's time to replenish your electrolytes with Relyte from Redmond. Made with Redmond's Real Salt, this clean formula provides essential electrolytes like sodium, potassium, and magnesium without any sugar or artificial ingredients. Perfect for those under stress, fasting, or living an active lifestyle, Relyte helps restore hydration, improve energy, and support mental clarity. Visit RedmondLife.com/DrJockers and use code JOCKERS for 15% off today! Support your heart, brain, and overall wellness with Paleovalley's Wild Caught Fish Roe. This whole food source of Omega-3s is rich in EPA and DHA, helping to reduce inflammation and promote brain function. Take control of your health today and save 15% on your purchase at paleovalley.com/jockers with the code JOCKERS. If you've ever been told your labs look "normal" while still dealing with brain fog, low energy, poor sleep, or unexplained symptoms, I highly recommend checking out SuperPower Health. They go far beyond standard blood work with over 100 biomarkers from one simple blood draw, giving you real insight into your hormones, metabolism, inflammation, nutrient status, toxins, and overall health. I also love that they track your results over time and give you access to an on-demand clinician team right through their app. Head to SuperPower.com and use code JOCKERS to save $20 off your membership. Healthy skin starts at the cellular level, which is why I'm a big fan of OneSkin. Their products were developed by longevity researchers using a proprietary peptide called OS-01, designed to target senescent cells and support healthier, younger-looking skin from the inside out. The science behind this is incredibly impressive, with multiple clinical studies and thousands of five-star reviews backing the results. Visit OneSkin.co/drjockers and use code DRJOCKERS to get 15% off your order today. "When your nervous system is balanced, everything works better—sleep, focus, mood, and relationships." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Get 15% off at RedmondLife.com/DrJockers using code JOCKERS. Save 15% at Paleovalley.com/Jockers with code JOCKERS. Save $20 on your membership at SuperPower.com using code JOCKERS. Get 15% off at OneSkin.co/DRJOCKERS using code DRJOCKERS. Connect with Michael Cohen: Website: centerforbrain.com Book: Neurofeedback 101 https://a.co/d/08t1Dul6 Book: The Mind Rewired https://a.co/d/08meFNFP Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Send us Fan MailIn Episode 153 of the Joint Dynamics Podcast, host Andrew Cox | Joint Dynamics dives deep into the high-stakes world of elite performance nutrition with Eliza Freney, the powerhouse behind The Rugby Dietitian. If you've ever viewed nutrition as an "add-on" to training, Eliza is here to shift your perspective: in the world of professional collision sports, nutrition isn't optional - it is infrastructure.With a resume that reads like a "who's who" of international sport - including roles as the Head of Performance Nutrition for Rugby Australia and the Wallabies, and current consultancy for the NRL's South Sydney Rabbitohs and New Zealand Basketball - Eliza brings a level of scientific rigor that is rarely seen outside of elite environments. We explore the physiological nuances of fueling different roles on the pitch, from the explosive power needs of a front-rower to the high-speed endurance requirements of a winger.A significant portion of today's conversation focuses on Eliza's cutting-edge research into Omega-3 fatty acids (DHA and EPA). We move beyond simple "heart health" to discuss the emerging and vital role these lipids play in concussion risk mitigation and cognitive recovery for athletes facing repetitive sub-concussive events. Whether you are a weekend warrior, a parent of a rising teenage star, or an elite professional, Eliza's insights into the "nutrition mindset" will change how you view your next meal.We also take a moment to acknowledge that rugby is truly in Eliza's DNA; while her father, Michael Freney, famously wore the gold jersey for the Wallabies, Eliza is the one now ensuring the modern era of players actually has the fuel to finish the full 80 minutes—perhaps the most important "assist" in the family history!*JD podcast show sponsor is Muvitality Medicinal Mushrooms for modern day health and wellness | Mu …Go to muvitality.com and use the code JD10 to receive a 10% discount on your purchase of Mu Functional mushrooms such as Lions Mane, Cordyceps, Chaga, Reishi, and Turkey tail functional mushroomsEnjoyHere are some useful links for this podcastIG @therugbydietition Relevant episodesEpisode 145 - All Blacks Secrets: Dr. Nic Gill on Building Rugby's Greatest Dynasty - https://podcasts.apple.com/hk/podcast/episode-145-all-blacks-secrets-dr-nic-gill-on-building/id1527374894?i=1000747675984Episode 148 - Controversial or Just Honest? Adam Meakins, The Sports Physio unfiltered on What Really Works - https://podcasts.apple.com/hk/podcast/episode-148-controversial-or-just-honest-adam-meakins/id1527374894?i=1000755542249JOINT DYNAMICS links:Joint Dynamics Facebook - https://www.facebook.com/JointDynamicsHongKong/Joint Dynamics Instagram -https://www.instagram.com/jointdynamics/Joint Dynamics Youtube - https://www.youtube.com/channel/UCRQZplKxZMSvtc6LxM5WckwJoint Dynamics Website - www.jointdynamics.com.hk Host - Andrew Cox - https://www.jointdynamics.com.hk/the-team/trainers/andrew-cox—------------------------------------------------------------------------------------------------------------------
Power plant water and steam chemistry is not a background task. It affects safety, reliability, metallurgy, production, and the decisions plant teams make under pressure. In Part 1 of this conversation, Trace Blackmore, CWT, welcomes Bradley Buecker of SAMCO Technologies and Buecker Associates to examine what happens when familiar assumptions go unchallenged. Safety Comes First in High-Energy Systems Bradley begins with the lesson that has shaped decades of his work: safety. Power and industrial systems involve heat, flow, moving equipment, chemicals, confined spaces, lockout/tagout requirements, and PPE decisions that cannot be treated casually. That safety lens carries directly into the discussion of flow accelerated corrosion, or FAC. Bradley explains how older thinking around removing all oxygen from high-pressure steam generation systems helped shape all-volatile treatment reducing programs. However, research following a catastrophic 1986 feedwater line failure showed that chemistry, flow conditions, pH, temperature, and piping geometry can combine to thin protective oxide layers on carbon steel. "Water is Water" Is a Risky Mindset Trace and Bradley then challenge one of the most expensive assumptions in industrial plants: "water is water." Bradley explains why boiler makeup treatment, softener performance, hardness control, and operating discipline deserve attention before failures appear. Low-pressure and intermediate-pressure boilers may tolerate a range of dissolved solids, but hardness remains a serious threat. Calcium and magnesium can form calcium carbonate scale in hot boiler environments, especially when softeners are poorly maintained, overrun, or bypassed to keep production moving. Bradley shares examples where short-term operating decisions led to tube failures, re-tubing, hydrogen damage, and costly downtime. Layup, Stainless Steel, and Data Before Assumptions The conversation also covers proper layup, oxygen and moisture corrosion, nitrogen capping, dehumidified air, vapor phase corrosion inhibitors, and why idle systems need a plan. Bradley reminds listeners that protecting the boiler is not enough; condensers, low-pressure turbines, and other surfaces also matter. Finally, Bradley discusses stainless steel selection and why 304L or 316L should never be treated as a universal cure for corrosion. Chlorides, deposits, cycling in cooling towers, and pitting risk all need to be evaluated before materials decisions become expensive lessons. His closed cooling water case history reinforces the same principle: do not clean, treat, or specify based on assumption. Get the data first. Good water treatment decisions protect people, equipment, and production. This conversation is a reminder that experience matters, but so does the willingness to ask questions, challenge old habits, and reach out before a problem becomes a failure. Listen to the full conversation above. Explore related episodes below. Stay engaged, keep learning, and continue scaling up your knowledge! Timestamps 02:30 — Trace opens the episode by thanking listeners for encouraging him to share more personal reflections, showing how audience feedback shapes the podcast. 04:50 — Trace highlights upcoming industry events, including ACE26 and The Water Expo, and reminds water professionals to use the Scaling UP! H2O events section for career and networking opportunities. 07:10 — James McDonald presents Words of Water, defining the mole and keeping technical learning approachable for industrial water professionals. 09:10 — Trace welcomes Bradley Buecker of SAMCO Technologies and Buecker Associates as his lab partner for the episode. 10:00 — Bradley summarizes his career across coal-fired utilities, water treatment, steam generation chemistry, air emissions control, engineering firms, and water treatment companies. 11:30 — Bradley identifies safety as the most important lesson from his career, emphasizing PPE, lockout/tagout, confined spaces, chemicals, and high-energy systems. 12:50 — Bradley challenges the phrase "that's the way we've always done it," pointing to changes in membrane technologies, high-pressure steam chemistry, and cooling water treatment. 13:50 — Bradley introduces two major concerns: flow accelerated corrosion and the dangerous assumption that "water is water." 15:10 — Bradley explains the historical focus on removing oxygen from high-pressure steam systems using mechanical deaerators and reducing agents. 16:10 — Bradley describes the 1986 nuclear plant feedwater line failure that killed four personnel and intensified research into FAC. 18:50 — Bradley explains how AVTR chemistry, flow conditions, fittings, pH, and temperature can thin protective oxide layers and lead to catastrophic failure. 20:20 — Bradley discusses how high-purity feedwater with a small amount of dissolved oxygen can form a denser oxide layer that protects carbon steel from FAC. 23:50 — Bradley compares oxygen scavengers, including sulfite, hydrazine, carbohydrazide, DHA, and methyl ethyl ketoxime, and explains where their use differs. 26:50 — Trace and Bradley unpack why "water is water" often means water is treated as the last priority instead of the first. 28:10 — Bradley explains why sodium softening, hardness control, and boiler makeup treatment are essential for low- and intermediate-pressure boilers. 31:00 — Bradley shares examples of softener bypass decisions that can lead to boiler damage, tube failures, re-tubing, and costly downtime. 36:50 — Bradley explains why layup matters, especially when water cools, air enters, and localized corrosion develops inside idle equipment. 42:00 — Bradley warns that stainless steel is not a cure-all and explains how chloride concentration and pitting risk affect 304L and 316L applications. 45:50 — Bradley shares a closed cooling water case history where black material was assumed to be iron but turned out to be bitumen from an unsuitable pipe liner. 51:00 — Bradley stresses the need for data before action, explaining how an incorrect cleaning assumption could have compounded a seven-figure materials mistake. 52:50 — Trace and Bradley discuss the value of experience and why younger professionals should seek training, conferences, vendors, and technical networks. 54:20 — Bradley speaks to the importance of mentorship as experienced professionals retire and critical industry knowledge risks being lost. 59:40 — Trace closes Part 1 and previews Part 2, which will continue the conversation on oxygen scavengers, pretreatment stories, and Bradley's career. Connect with Bradley Buecker Email: bueckerb@samcotech.com LinkedIn: https://www.linkedin.com/in/bradley-buecker-705b9021/ Guest Resources Mentioned ASME CRTD 34 / ASME Consensus document Barry Dooley – "Flow-Accelerated Corrosion in Fossil and Combined Cycle/HRSG Plants" IAPWS Technical Guidance Document – Volatile Treatments Brad Buecker's HRSG issues: Reemphasizing the importance of flow-accelerated corrosion control – Part 1 Industrial water and steam treatment will be important for a long time Part 1 The importance of industrial water and steam treatment, Part 2 The importance of industrial water and steam treatment, Part 3 The importance of industrial water and steam treatment, Part 4 The importance of industrial water and steam treatment, Part 4.5 The importance of industrial water and steam treatment, Part 5 The importance of industrial water and steam treatment, Part 6 The importance of industrial water and steam treatment, Part 7 Surry Unit 2 feedwater line rupture documentation Scaling UP! H2O Resources Mentioned AWT (Association of Water Technologies) Scaling UP! H2O Academy video courses Submit a Show Idea The Rising Tide Mastermind Words of Water with James McDonald Today's definition is the standard SI unit for the amount of substance, defined exactly as 6.02214076 x 10^23 elementary entities, such as atoms or molecules. Can you guess the word or phrase? 2026 Events for Water Professionals Check out our Scaling UP! H2O Events Calendar where we've listed every event Water Treaters should be aware of by clicking HERE.
In this episode, Dennis Campbell II, DHA, RN, FACHE, President, ECU Health Beaufort - a campus of ECHUMC, discusses the future of rural healthcare, workforce development, and expanding access to high-quality care close to home. He also shares leadership insights from his journey as a bedside nurse to hospital president and highlights the importance of purpose-driven leadership, innovation, and community connection.
For more information and support, join us at https://thecirsgroup.com Jacie and Barbara cover Phase Two (part two of five) of the Shoemaker Protocol for CIRS, focusing on foundational steps before starting binders: Lipid replacement therapy (primarily fish oil) to lower inflammation and help prevent common binder side effects like fatigue, constipation, and overall dryness, with Shoemaker-recommended omega-3 dosing (EPA 2,400 mg and DHA 1,800 mg daily) and cautions about blood-thinning; Limbic retraining to address errant threat signals from chronic illness, with nuance that intensive programs can be too difficult early on and may work better once out of exposure and/or on binders, while also warning against symptom suppression without addressing root causes; And the critical priority of getting out of exposure through testing (dust tests for mold, endotoxins, and actinos), remediation or moving, and exploring hidden, internal exposures that can cause plateaus or backslides in your health. Be sure to subscribe so you don't miss the next episode, all about Phase Three, removing the toxic burden! For more information and support, join us at https://thecirsgroup.com TIMESTAMPS 00:00 Phase Two of the Shoemaker Protocol 01:25 Why this foundational phase matters 02:54 What is Lipid Replacement? and why is it important? 06:17 Fish Oil / lipid dosing tips 08:04 Limbic Retraining explained 10:51 When Limbic Retraining backfires 14:23 Hyperreactivity Catch-22 18:25 Get out of exposure 20:42 Hidden exposures and healing stalls 22:27 Key takeaways and next phase 24:08 Wrap up and resources For more information and support, join us at https://thecirsgroup.com Check out these episodes mentioned in this episode: Interview with Michael Schrantz about remediation: https://youtu.be/_BEwFVdpRcY?si=mzNeGslwGjaYhWqi Interview with Bill Weber about testing your home: https://youtu.be/RlKjTqVAeNU?si=Eymfvcdk4G6kzylV Interview with Kendra Seymour on choosing a remediator or IEP: https://youtu.be/zmt9e42LLac?si=cTTvunobvEt8YL_n Dust testing 101: https://youtu.be/nRrZs7xbXcc?si=55oXFRCV5kO_p0JD Endotoxin episode: https://youtu.be/O0iKndNzfYA?si=X-iX1NoRO2U7U-QV Actinos episode part one: https://youtu.be/yf9EoTbyAEo?si=d2KUSzNpX2cs0DKE and Part two: https://youtu.be/2rCXhUP6dbY?si=wDHiSy58Vw5fZ5fa Order Jacie's book! The 30 Day Carnivore Bootcamp: https://a.co/d/7MgHrRs The CIRS Group: Support Community: https://thecirsgroup.com Instagram: https://www.instagram.com/thecirsgroup/ Find Jacie for carnivore, lifestyle and limbic resources: Jacie's book on the Carnivore diet! https://a.co/d/8ZKCqz0 Instagram: https://www.instagram.com/ladycarnivory YouTube: https://www.youtube.com/@LadyCarnivory Blog: https://www.ladycarnivory.com/ Find Barbara for business/finance tips and coaching: Website: https://www.actlikebarbara.com/ Instagram: https://www.instagram.com/actlikebarbara/ YouTube: https://www.youtube.com/@actlikebarbara Jacie is a Shoemaker certified Proficiency Partner, NASM certified nutrition coach, author, and carnivore recipe developer determined to share the life changing information of carnivore and CIRS to anyone who will listen. Barbara is a business and fitness coach, CIRS and ADHD advocate, writer, speaker, and a big fan of health and freedom. Together, they co-founded The CIRS Group, an online support community to help people that are struggling with their CIRS diagnosis and treatment.
In this episode, Dr. Jockers sits down with Dr. Chris Motley to uncover the hidden signs of parasite infections and how they may be impacting your sleep, energy, digestion, mood, and metabolism. They break down why so many people unknowingly carry parasites and the symptoms that are often overlooked. You'll discover how parasites thrive in toxic environments, where they tend to hide in the body, and why issues like gut dysfunction, stress, and poor detoxification can make infections harder to overcome. The conversation also explores the connection between parasites, mood changes, and nervous system health. The episode also dives into natural parasite-cleansing strategies, including the most effective herbs, detox practices, lymphatic support techniques, and lifestyle habits that help the body heal and become more resilient long term. In This Episode: 00:00 Parasites And Neck Pain 02:14 Dad's Mystery Illness 03:02 Radionics And Liver Clues 05:49 Gallbladder Meridian Breakthrough 07:53 Where Parasites Hide 11:30 Common Parasites Sources 13:12 Key Symptoms To Watch 14:15 Why Some Get Sicker 16:22 Toxins Metals And Load 17:22 Trauma Liver And Parasites 21:35 Testing Options And Limits 24:22 Blood Markers And Patterns 29:09 Herbs And Homeopathics 31:11 Herb Cycling Strategy 31:54 Roundworm Protocol Basics 32:55 Blastocystis Remedies 36:28 Mimosa Pudica Velcro 37:39 Parasite Proof Stories 41:11 Full Moon Cleanse Timing 46:46 Eggs Lymph Drainage 50:38 Binders And Constipation 51:41 Preventing Reinfection 54:39 Wrap Up And Outro If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday. If you're feeling wired, tired, and depleted, it's time to replenish your electrolytes with Relyte from Redmond. Made with Redmond's Real Salt, this clean formula provides essential electrolytes like sodium, potassium, and magnesium without any sugar or artificial ingredients. Perfect for those under stress, fasting, or living an active lifestyle, Relyte helps restore hydration, improve energy, and support mental clarity. Visit RedmondLife.com/DrJockers and use code JOCKERS for 15% off today! Dealing with fine lines, dull skin, or skin that just doesn't look as healthy and vibrant as it used to? The Bon Charge Red Light Face Mask is an easy way to support healthier, younger looking skin right from home. It uses red and near infrared light therapy to help improve skin elasticity, reduce visible signs of aging, calm inflammation and redness, and support a clearer, more radiant complexion. It's lightweight, cordless, and only takes about 10 to 20 minutes a day to use. Right now, you can get 15% off your order plus free shipping and a 12 month warranty when you go to boncharge.com and use promo code DRJOCKERS at checkout. Fuel your body with clean, high-quality protein from ButcherBox. They deliver 100% grass-fed beef, free-range organic chicken, crate-free pork, and wild-caught seafood straight to your door—making it easy to support your energy, metabolism, and overall health. For a limited time, get your choice of chicken breast or top sirloin for a year, or ground beef for life, plus $20 off your first box. Visit ButcherBox.com/DrJockers to claim this special offer. Support your heart, brain, and overall wellness with Paleovalley's Wild Caught Fish Roe. This whole food source of Omega-3s is rich in EPA and DHA, helping to reduce inflammation and promote brain function. Take control of your health today and save 15% on your purchase at paleovalley.com/jockers with the code JOCKERS. "Parasites are masters at hiding. They can trick your body into thinking they belong there while silently draining your energy." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Visit RedmondLife.com/DrJockers and use code JOCKERS for 15% off today! Visit boncharge.com and use promo code DRJOCKERS at checkout for 15% Visit ButcherBox.com/DrJockers to claim this special offer Save 15% on your purchase at paleovalley.com/jockers with the code JOCKERS. Connect with Dr. Chris Motley: Website: https://www.doctormotley.com/ Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
For thirty years, the supplement aisle has sold fish oil as one of the simplest decisions you can make for your brain. In 2026, two research teams on opposite sides of the world published papers that complicate that story, and the literature behind them has been building for almost twenty years.IN THIS INVESTIGATIONWhat a 2026 ADNI cohort study of 800+ older adults actually foundWhy faster cognitive decline in fish oil users showed up on every measureWhat the brain imaging revealed when classic Alzheimer's pathology came back negativeThe 2026 Cell Reports mechanism work in repetitive brain injuryWhy EPA and DHA do different things inside the brain, and why most trials ignored the differenceTwenty years of cognitive trials nobody connected, including a 2006 trial whose biomarkers, re-analyzed in 2021, told a different storyWhat the 2026 authors themselves said about how to read their own findingsDose, baseline status, oil quality, and physiological context; the conditions the supplement aisle has never asked aboutWhat twenty years of brain literature actually supports if you take fish oil todaySubscribe for more investigations.
Broadcast from KSQD, Santa Cruz on 5-14-2026: An emailer from Switzerland follows up on the case of neurological symptoms, warning about the fox tapeworm Echinococcus multilocularis from unwashed garden vegetables and tick-borne encephalitis requiring the FSME vaccine available in Europe. Dr. Dawn adds that cysticercosis from undercooked pork leaves calcified brain lesions detectable on CT scans. Dr. Dawn covers the Andes hantavirus outbreak that sickened at least eleven people on a cruise ship, with the virus spreading person-to-person unlike other hantaviruses. She explains that Andes virus grows to unusually high levels in blood and resists antimicrobial compounds in human saliva, with super-spreaders driving transmission chains. British paratroopers had to parachute medical supplies to an infected passenger on remote Tristan da Cunha island. Dr. Dawn reviews brain health supplements with UCLA longevity expert Gary Small. Both recommend curcumin (500-1,000mg) for anti-inflammatory effects and CoQ10 for statin users. She endorses multivitamins and high-quality fish oil but considers creatine, phosphatidylserine, and nicotinamide riboside insufficiently proven for cognitive enhancement. A caller asks about supplements and testosterone for a 77-year-old. Dr. Dawn recommends topical testosterone (patches, creams, gels) over injections to avoid testicular shrinkage and elevated sex hormone-binding globulin. She emphasizes protein intake matching one's age in grams, branched-chain amino acids during exercise, and warns against fasted training after age 65. An emailer shares news that PCOS is being renamed to polyendocrine metabolic ovarian syndrome (PMOS) because many patients lack ovarian cysts, and genetic males can also have the condition. Dr. Dawn explains it's fundamentally an endocrine and metabolic disorder involving insulin resistance, elevated testosterone, and DHEA dysregulation. A study found that infrasound—low-frequency sound below human hearing range—elevated cortisol and worsened mood in subjects who didn't know and couldn't detect it was playing. Old buildings generate infrasound through aging boilers, ventilation ducts, and metal pipes, potentially explaining why, beyond autosuggestion, that old "haunted" houses feel spooky.
Happiness isn't a nonstop high. For us, the real win is an elevated baseline: that steady, grounded sense of wellness that makes you more resilient, less reactive, and far harder to knock off course when a day goes sideways.We unpack why that baseline is built less by hype and more by biology. I share why omega-3 fatty acids matter so much for mental health, mood, and brain function, especially the marine forms EPA and DHA. We talk about how your brain relies on healthy fats for cell membrane function, why omega-3s are often discussed in relation to depression support, and how they can influence stress response through the HPA axis and cortisol regulation. If you've ever wondered why you can “know” the right mindset but still feel anxious, flat, or tangled in your emotions, this is the missing link: the state of your body shapes the state of your mind.Beyond the non-negotiables of quality sleep, exercise, and balanced meals that meet real nutrient requirements, I lay out a simple, evidence-based supplement routine your brain and body need to make the chemicals tied to motivation, focus, and calm. This is unglamorous work, but it's the work that makes thriving feel repeatable.If this helped you, subscribe, share it with one person who needs an elevated baseline, and leave a rating and review so more people can find the tools to feel better every day.Text Me Your Thoughts and IdeasSupport the showBrought to you by Angela Shurina Certified Health, Sleep, Performance & Executive Coach 360 with 18 years of experience helping people change to feel, be and do their best.
This week, we recap the "Tax Gas Not Beer" tour and tear down Albo's hollow gas reform—a policy that raises zero dollars and won't even kick in until after the next election. We also dive into a heated housing showdown between economist Richard Dennis and developer Jack Henderson, debating everything from capital gains tax to whether the government can actually build affordable homes. Bypass the Algorithm, Sign up to the Punter Times Newsletter https://www.punterspolitics.com/pages/email-sign-up Support We the Punters on PATREON (https://www.patreon.com/punterspolitics) Buy Punters Stickers & T-shirts (https://www.punterspolitics.com/) Fact checks welcome citations NECESSARY! Here are the citations Jack and Richard sent through for claims around the DHA at the end of the debate there. https://docs.google.com/document/d/1DMFmkzUCV1UKUJ2EVlmH8WTlvU1FWrbiE5itBVxC0uc/edit?usp=sharing
Podcast 329 - Dine Around Dunwoody Brings Food and Music to New Spots Across the City - Tim Brown Food Truck Thursdays is getting a refresh, and DHA President Tim Brown joined me to break it all down. After 15 years as a Dunwoody staple, the Dunwoody Homeowners Association decided it was time to shake things up, and what they came up with is worth getting excited about. Dine Around Dunwoody is the new series: five events from May through October, each one at a different location around the city. Think family-friendly food trucks, live music or DJs, and yes, the Chick-fil-A cow. Instead of everyone coming to Brook Run every time, the DHA is bringing the party to Spruill Center's hidden courtyard, the amphitheater at High Street, and spots a lot of Dunwoody residents have honestly never visited. And Moondog Growlers is back as the adult beverage partner, which Tim says was the most-requested community return of the year. This episode is also a great window into how much the DHA has evolved lately. New logo, new website, a growing social media presence, and a slogan that says it all: "Neighbors Connecting Neighbors." Tim gives a lot of credit to the team around him, and it shows. The kickoff is May 21 at Brook Run Park from 5:30 to 9 PM. Full episode summary lives here: whatsupdunwoody.com/podcast-329
Send us Fan MailHow omega-3 fats in human health, including dietary intake needs, supplements, & omega fat testing.TOPICS DISCUSSED:ω-3 chemistry: EPA and DHA differ from plant ALA in chain length and double-bond count, making them structurally and biologically distinct — and largely irreplaceable by ALA conversion.ALA-to-EPA/DHA conversion: A small percentage of dietary ALA converts to EPA, and conversion to DHA is even lower; vegans rely on this inefficient pathway for all long-chain omega-3s.Cardiovascular mechanisms: ω-3s lower triglycerides, reduce platelet stickiness, improve endothelial function, and slow resting heart rate, reducing cardiovascular risk.ω-3 Index: Defined as red blood cell EPA+DHA as a percent of total fatty acids; 8–12% is the target range, while most Americans sit around 4–5%.Brain & dementia risk: Higher DHA blood levels are associated with significantly lower risk of dementia and Alzheimer's in large cohorts including the UK Biobank and Framingham.Linoleic acid nuance: Higher blood levels of dietary linoleic acid (omega-6) associate with lower dementia and cardiovascular risk; downstream omega-6 metabolites — not linoleic acid itself — associate with adverse outcomes.Supplementation practicalities: Most people need 1–2 g/day of EPA+DHA to reach an ω-3 Index >8%; oxidation concerns with fish oil supplements may be overstated.ABOUT THE GUEST: Bill Harris, PhD is founder of both OmegaQuant Laboratory and the Fatty Acid Research Institute (Sioux Falls, SD), where his work centers on blood fatty acid biomarkers as predictors of disease risk in large population cohort studies.KNOW YOURSELF:OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.RELATED EPISODE:M&M 134: Omega Fats, Vegetable & Seed Oils, Sugar, Processed Food, Metabolic Health & Dietary Origins of Chronic Inflammatory DiSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
In this episode, Dr. Jockers sits down with Dr. Shivani Gupta to explore how inflammation is the root cause of many chronic health issues. Dr. Gupta shares her journey bridging Ayurvedic wisdom with modern science to reveal how super herbs and spices like turmeric can combat inflammation at its core. You'll learn how Ayurveda identifies unique body types or doshas and how this understanding can help tailor your nutrition and lifestyle to reduce inflammation. Dr. Gupta explains how aligning with your body's natural rhythms and using personalized nutrition strategies can create lasting health benefits. Dr. Gupta also dives into the power of gut health, highlighting how an imbalanced gut can fuel systemic inflammation. Tune in to discover practical Ayurvedic practices that support digestive health and reduce inflammation, including tea time rituals and stress management techniques. In This Episode: 00:00 Inflammaging Not Aging 00:24 Meet Dr Shivani Gupta 05:49 Interview Begins Book Origins 08:31 What Is Chronic Inflammation 11:17 Gut Health And Leaky Gut 13:38 Ayurvedic Daily Gut Rituals 15:51 Elemental Design Doshas 17:44 Vata Pitta Kapha Explained 23:10 Dosha Blends And Balance 27:06 Foods For Each Dosha 28:58 Cooling Summer Foods 29:39 Kapha Balancing Diet 30:19 Finding Your Dosha 31:03 Menopause as Vata Season 32:44 Mental Inflammation 36:57 Circadian Rhythm Basics 39:02 Tea Time Mindfulness 40:51 Nighttime Sleep Routine 46:29 Deep Sleep Tea Herbs 47:10 Super Spice Protocols 52:41 Turmeric Absorption Tips 54:20 Cycling Supplements 55:48 Final Takeaways Support your heart, brain, and overall wellness with Paleovalley's Wild Caught Fish Roe. This whole food source of Omega-3s is rich in EPA and DHA, helping to reduce inflammation and promote brain function. Take control of your health today and save 15% on your purchase at paleovalley.com/jockers with the code JOCKERS. If you want practical, natural strategies to balance your hormones, heal your gut, boost your energy, and slow aging, don't miss The Dr. Josh Axe Show. Dr. Axe blends ancient wisdom with cutting-edge science and brings on world-class experts for unfiltered conversations you won't hear anywhere else. Transform your health from the inside out and subscribe to The Dr. Josh Axe Show, with new episodes every Monday and Thursday. If you're feeling wired, tired, and depleted, it's time to replenish your electrolytes with Relight from Redmond. Made with Redmond's Real Salt, this clean formula provides essential electrolytes like sodium, potassium, and magnesium without any sugar or artificial ingredients. Perfect for those under stress, fasting, or living an active lifestyle, Relight helps restore hydration, improve energy, and support mental clarity. Visit RedmondLife.com/DrJockers and use code JOCKERS for 15% off today! It's time to take your oral care to the next level with BON CHARGE's Red Light Toothbrush – order yours today! For a limited time, my listeners get 15% off when you order from boncharge.com and use my exclusive promo code DRJOCKERS at checkout You'll also get free shipping and a 12-month warranty. Go now to get this exclusive offer! That's boncharge.com with promo code DRJOCKERS to get 15% off Ensure pure, clean water with CovePure's advanced filtration system. It removes up to 99.9% of contaminants, including harmful PFAS, heavy metals, and fluoride, so you can enjoy safe, toxin-free water. For a limited time, get $250 off your order at covepure.com/drjockers. Momentum Shake is a game-changer, replacing multiple supplements with one simple scoop. Packed with collagen, hyaluronic acid, and Lion's Mane for cognitive support, it boosts your energy, mental clarity, and strength without the overwhelm of complex routines. Get your free welcome kit and travel collection worth $70 at momentumshake.com/drjockers. "Most people don't have an aging problem, they have an inflammation problem driven by diet, stress, and toxins stacking over time." Subscribe to the podcast on: Apple Podcast Stitcher Spotify PodBean TuneIn Radio Resources: Support heart, brain, and overall wellness with Paleovalley's Wild Caught Fish Roe and save 15%: https://paleovalley.com/jockers Enjoy pure, clean water with CovePure's advanced filtration system and get $250 off your order: https://covepure.com/drjockers Simplify your supplement routine with Momentum Shake and get a free welcome kit and travel collection worth $70: https://momentumshake.com/drjockers Stay hydrated with Redmond Life's Relight electrolytes and experience better energy, clarity, and strength: https://redmond.life/drjockers Improve your oral health with Bond Charge's Red Light Toothbrush and enjoy free shipping and a 12-month warranty: https://bondcharge.com/drjockers Connect with Dr. Shivani Gupta: Book: https://a.co/d/01YI6LXr Connect with Dr. Jockers: Instagram – https://www.instagram.com/drjockers/ Facebook – https:/www.facebook.com/DrDavidJockers YouTube – https://www.youtube.com/user/djockers Website – https://drjockers.com/ If you are interested in being a guest on the show, we would love to hear from you! Please contact us here! - https://drjockers.com/join-us-dr-jockers-functional-nutrition-podcast/
Dr. Judy Morgan and Dr. Linda Loudon discuss the canine wellness movement, emphasizing the importance of holistic pet health coaching and nutrition. They highlight the challenges in veterinary care, including long wait times and high costs, and the role of pet health coaches in providing individualized care. Dr. Loudon shares her experience with the Dog Mom Society, which supports pet parents with trusted information. They stress the need for proper training and certification for pet health coaches and the importance of working collaboratively with veterinarians. Dr. Loudon also offers business advice for aspiring pet health coaches, emphasizing the necessity of learning both the business and clinical aspects of the field. OFFER: Dr. Louden offers a free one month trial in my membership in her Dog Mom Society. https://thedogmomsociety.circle.so/checkout/dr-judy-trial Your Social Media URLs or Tags Instagram: @drloudon Facebook: https://www.facebook.com/drloudonvet LinkedIn: www.linkedin.com/in/drloudon Your website URL https://www.drloudonk9.com/ PRODUCT SPOTLIGHT #1At K9/Feline Natural they believe nature knows best. That's why their premium pet food is proudly made using only grass fed, grass finished meat, never grain fed, never compromised. That means higher omega threes, conjugated linoleic acids, and lower saturated fats and bacterial counts, supporting shiny coats, vibrant energy and overall wellness. Their recipes are rich in high quality meat, including nutrient dense green tripe for gut health and enhanced with muscles, a superfood packed with EPA and DHA to help maintain a normal inflammatory response. K9/Feline Natural is a diet that's biologically appropriate, scientifically sound and naturally powerful. Use code DRJUDY20 for a 20% off discount on US.K9FelineNatural.com. For clean, natural nutrition inspired by nature and backed by science. PRODUCT SPOTLIGHT #2Thank you to Tickless for sponsoring this podcast episode. Tickless is a global leader in chemical free products designed to help prevent tick bites. In addition to their gentle ultrasonic technology devices trusted in more than 50 countries, Tickless also offers non toxic collars, Spot ons and wet wipes in Europe. Their mission is to provide smart, family friendly solutions for pets and people who love the outdoors. Tickless pet is their best known device, a simple, durable option for all sizes of pets, from tiny breeds to large adventure dogs. It's safe to use daily when attached to a collar or harness. Tickless Mini is the compact, rechargeable version created for pet parents who want long lasting convenience in a modern, lightweight design, and for your indoor environment, there's Tickless Home developed to support pets dealing with dust mites, while also helping to prevent tick and flea bites. It may ease issues related to dust mites offering an additional layer of comfort at home. All tickless devices operate without chemicals, and they're designed to avoid allergic reactions, giving your family and pets more peace of mind, while also being cost effective. To learn more, visit www.ticklessusa.com, and as a listener of this podcast, you can enjoy 15% off your order with code DRJUDY at checkout. PRODUCT SPOTLIGHT #3 You've heard us say it many times, fresh real food is the foundation of health. The team here at Naturally Healthy Pets has been feeding raw for years, and we love how My Pet Carnivore can build a personalized Raw Meal plan that fits your dog's needs perfectly in just a few minutes. Raw feeding should never be overwhelming. Since 2010 they've provided the highest quality, nutritious raw food from trusted local sources, and now they even offer the convenience of customized kits for your needs. The My Pet Carnivore raw feeding bundles make starting easy with variety and balanced rotation, or they also carry the same organs that Dr Judy uses in her pup loaf recipes, heart, liver and gizzards, so you can confidently build homemade meals yourself. Not ready to fully go raw yet, that's okay. They also have boneless lines that are safe to cook. It's a great first step into fresher feeding. Use code TRUST for 15% off your first order at mypetcarnivore.com and be sure to check out their educational blog and join their email list for ongoing deals.
Send us Fan MailHow dietary fatty acids regulate the initiation, propagation, and resolution of inflammation.TOPICS DISCUSSED:Parenteral nutrition history: IV nutrition evolved from soybean oil alone in the 1960s to complex blends including fish oil as the biology of ω-3s became understood.Three phases of inflammation: Initiation, propagation (driven by ω-6–derived prostaglandins and leukotrienes), and active resolution (driven by ω-3-derived resolvins and protectins).Pro-resolving mediators: Resolution is an active biological process, not passive; EPA and DHA generate resolvins and protectins that actively terminate inflammation.Aspirin's ω-3 mechanism: Aspirin inhibits arachidonic acid metabolism but allows EPA/DHA to access COX-2, upregulating pro-resolution mediators — a likely underappreciated mechanism of action.Cell membrane competition: EPA and DHA physically displace arachidonic acid in membranes, shifting the balance of mediators produced and improving resolution capacity.Linoleic acid & EPA synthesis: High linoleic acid intake saturates shared desaturase enzymes, inhibiting the body's conversion of ALA to EPA — meaning reducing ω-6 can raise ω-3 levels without supplementation.Dose & timing of ω-3 incorporation: ~2g/day of EPA+DHA shifts the arachidonic acid-to-EPA ratio enough to measurably reduce prostaglandin E2 production; white blood cells reflect changes within a month.ABOUT THE GUEST: Philip Calder, PhD is Professor of Nutritional Immunology in the Faculty of Medicine at the University of Southampton. His research focuses on how dietary fatty acids — particularly omega-3s — modulate immune responses and inflammatory processes across clinical and healthy populations.RELATED EPISODE:M&M 200: Dietary Fats & Seed Oils in Inflammation, Colon Cancer & Chronic Disease | Tim Yeatman & Ganesh HaladeSupport the showHealth Products by M&M Partners:AquaTru: Water filtration devices that remove microplastics, metals, bacteria, and more from your drinking water. Through link, $100 off AquaTru Carafe, Classic & Under Sink Units; $300 off Freestanding models.OmegaQuant: At-home blood testing to see fatty acid profiles, including omega-3 fatty acids. Use link to see options and support M&M.SiPhox Health: Comprehensive, cost-effective bloodwork from the comfort of home. Use code TRIKOMES for 20% off.KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime)Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they're hiding, with this easy-to-use mobile app.SporesMD: Premium mushrooms products (gourmet mushrooms, nootropics, research). Use code 'nickjikomes' for 20% off.For all the ways you can support my efforts
The Real Truth About Health Free 17 Day Live Online Conference Podcast
Discover how omega-3s like DHA and EPA protect against dry eye, macular degeneration, and retinal disease plus plant-based alternatives. #Omega3s #EyeHydration #PlantBasedVision #HealthTalks
Hallo Wechseljahre! - Kraftvoll und ausgeglichen durch die Wechseljahre
100 Folgen. Hunderte von Frauen. Heute teile ich meine größten Erkenntnisse — und was wirklich einen Unterschied macht.*WERBUNG: Sponsor der heutigen Episode ist NORSAN.Omega-3-Fettsäuren gehören zu den mehrfach ungesättigten Fettsäuren. Der Körper kann sie nicht selbst herstellen und ist daher darauf angewiesen, dass diese über die Nahrung aufgenommen werden. Insbesondere die Omega-3-Fettsäuren EPA und DHA sind für unsere Gesundheit von hoher Bedeutung.https://www.norsan.de/?norsan=1525Erwähnte Links:Kurs Kraft&Balance: https://courses.optimum-you.com/kraftundbalanceDEINE VITAL FORMEL: https://courses.optimum-you.com/deine-vital-formelInstagram: https://www.instagram.com/youroptimum/Corporate Workshops: DM @youroptimumWas ich höre: Viele Frauen fühlen sich noch immer alleingelassen. Dazu zwei Extreme: kaum Wissen oder totale Überforderung. Genau das möchte ich ändern.Hormone: Mehr Aufklärung, weniger Angst. Mit oder ohne HET — Lifestyle macht in jedem Fall den Unterschied.Bewegung: Krafttraining 2–3x die Woche ist eine Lebensversicherung.
I break down what happens week-by-week if you eat sardines for 30 days and how omega-3s, DHA, and protein can improve brain function, fat loss, and energy. Learn how sardines help reduce inflammation, stabilize blood sugar, and eliminate brain fog naturally.I just released another video that walks you through exactly how to lose weight rapidly without wrecking your hormones or crashing your energy.Watch it here: https://youtu.be/iSpdK2vNjP0GET A CUSTOMIZED WEIGHT LOSS PLAN: Have a free 1-on-1 call with our Expert Nutritionists
Trim Healthy Podcast w/Serene & Pearl (and some guy named Danny)
In this episode, we talk about why postpartum nutrition deserves far more attention, and why the weeks and months after birth are such an important season for healing, rebuilding, and nourishment. We explore the physical demands of postpartum life, from tissue repair and blood loss to milk production, and why so many women feel pressure to “bounce back” before their bodies are truly ready. You'll hear a practical conversation about protein, nutrient-dense foods, healthy fats, gentle carbs, and why eating enough in the postpartum season matters so much. We also discuss how lactation can place major demands on the body, why muscle loss and depletion can happen when nourishment is lacking, and how simple, wise choices can support recovery without turning health into something stressful or extreme. We also dive into postpartum exercise, the cultural pressure to rush back into workouts, and why rest, posture, walking, breathing, and gradual rebuilding may be far more supportive than pushing too hard too soon. Plus, we talk about real postpartum struggles like exhaustion, hunger, mood shifts, recovery challenges, and the importance of giving women practical support instead of unrealistic expectations. We also touch on collagen, connective tissue repair, brain-supportive nutrients like DHA and vitamin D, and why a simple, balanced approach to food can make such a difference during the postpartum season. If you want encouragement and practical insight for nourishing your body after birth, supporting recovery, and caring for yourself in a more sustainable way, this episode is full of helpful conversation and honest perspective. Learn more about your ad choices. Visit megaphone.fm/adchoices
This podcast is listener-supported. To receive new posts and support my work, consider becoming a free or paid subscriber.Our culinary tour of Italy continues in Tuscany, a region whose cypress-lined landscapes and medieval hill towns define the quintessential Italian dream. This episode focuses on a cuisine where the philosophy of cucina povera meets world-class agricultural products, creating a table that is naturally plant-forward and elegantly simple.In this installment of our Italian series, we dive into why Tuscans are known as “bean eaters” and how their famous unsalted bread serves as the perfect canvas for the region's pungent, peppery olive oil. From ancient Etruscan roots to the birthplace of the biscotto, we discover how Tuscany transforms humble ingredients like white beans, kale, and chestnuts into mouthwatering masterpieces.What This Episode Covers:* We dive into why Tuscans are affectionately called “bean eaters” and explore the many varieties of white beans* I discuss the unique characteristics of Tuscan olive oil* We explore the curious history of Tuscany's unsalted bread (pane sciocco) and how it led to the creation of classic “recycled” dishes like Panzanella and Ribollita.* This episode highlights the difference between crostini and bruschetta, including a warning about which traditional toppings to avoid.* I introduce the ancient pasta testaroli and the thick, hand-rolled pici noodles that are a staple of Sienese cuisine.* We look at the versatility of chickpea flour in traditional street foods like torta di ceci and farinata.* I share the fascinating history of biscotti, which were originally created as a rock-hard, long-shelf-life ration for Roman Legions.* We wrap up with a look at chestnut-based desserts and savory dishes, from chestnut gnocchi to the raisin-and-pine-nut-studded castagnaccio.
Our culinary tour of Italy continues as we head into Central Italy, a region defined by rolling hills, ancient forests, and a deep agricultural heritage. Comprising Tuscany, Umbria, Lazio, Abruzzo, and Le Marche, this area moves away from the tomato-heavy south toward a rustic palette of beans, grains, and earthy foraged treasures.What This Episode Covers:* We explore the temperate climate and topography of regions like Tuscany and Umbria that allow for specialty crops like farro, saffron, and Lacinato kale.* I explain the true origins of “cacciatore” (hunter-style) cooking and how foraged forest mushrooms and wild herbs define the authentic dish.* We discuss the fascinating history of saffron in Abruzzo and why it remains one of the most prized spices in the world.* This episode highlights the significant influence of Roman Jewish cuisine.* I break down the specific pasta shapes of the region.* We look at the differences in Italian bread traditions, from the saltless loaves of Tuscany to the “little horn” cornetti of the central breakfast bar.* I share tips for finding high-quality black truffles and truffle oils while avoiding synthetic flavorings.* We wrap up with a look at the “bean eaters” of Tuscany and the hearty, grain-based soups that define the central Italian table.
Dr. Jeffrey Bland, Founder and President of the Personalized Lifestyle Medicine Institute and President of Big Bold Health, is described as the “godfather of functional medicine.” He details the origins of functional medicine as a systems-biology, root-cause approach emphasizing diet, lifestyle, and supplements alongside conventional allopathic care, especially for chronic disease. Bland contrasts medication “number needed to treat” examples (statins and TNF-alpha blockers) with personalized lifestyle interventions, noting adherence challenges. He discusses GLP-1 weight-loss drugs as a major pharmacologic advance but raises concerns about long-term effects, discontinuation rates, side effects, and inadequate nutrition if food intake drops. Bland describes research on bitter compounds and gut “taste” receptors influencing GLP-1 and related hormones, links to Blue Zone diets, and introduces Big Bold Health's Himalayan Tartary Buckwheat and minimally processed, sustainably sourced fish oil products, the Omega-3 index, and targeted formulations with lutein/astaxanthin, plus ongoing clinical trials on immune aging and gene expression.
When many Americans think of Italian food, they immediately picture heavy, meat-laden dishes like chicken parmigiana, spaghetti and meatballs, and rich cheese sauces. But the reality of traditional Italian cuisine—especially in the South—is entirely different!In this episode, we dive deep into the culinary heartbeat of Southern Italy and explore how its sun-drenched climate, rich volcanic soil, and fascinating history naturally created a heavily plant-based food culture.We explore the brilliant tradition of cucina povera (peasant food), the history of Italian-American adaptations, and the diverse, flavorful dishes of regions like Campania, Calabria, and the island of Sicily. If you've ever wondered how to eat joyfully and sustainably in Italy, this episode proves that eating plant-based isn't a modern modification—it's a return to the country's most authentic, mouthwatering roots.In this episode we cover:* How Southern Italian immigrants adapted traditional, plant-heavy recipes with newfound access to meat in the U.S.* Why the South naturally features fresh produce, olive oil, and dried egg-free semolina pasta, compared to the butter and egg-rich North* The cucina povera (peasant food) philosophy of using accessible, local ingredients to create deeply flavorful, zero-waste meals* The evolution of pizza in Naples, and why the original, most traditional pies—like the Pizza Marinara or Rome's Pizza Bianca—are naturally cheese-free* How Greek, Arab, and Spanish conquests shaped the southern palate by bringing durum wheat, citrus, spices, and the tomato to the region* The unique, sweet-and-savory profile of Sicilian cuisine, featuring traditional staples like caponata, arancini, granita, and cannoli* A quick look at regional wines and liqueurs, including Limoncello, Nero d'Avola, and Marsala.
Most people buying "clean" supplements are unknowingly loading their bodies with heavy metals, rancid fish oil, and glyphosate, even inside products labeled organic and healthy. This episode breaks down exactly what the supplement industry refuses to tell you and gives you the tools to stop poisoning yourself every morning. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Grab a discount on Puori Products by visiting: https://puori.com/pages/dave?dt_id=1750934 Host Dave Asprey sits down with Oliver Amdrup-Chamby, founder and CEO of PUORI and a serial entrepreneur in the health and wellness space with over 16 years building what has become one of the most rigorously tested supplement brands in the world. Oliver opened the first CrossFit gym in Denmark in 2006, served as Regional Director of CrossFit HQ across Europe and the Middle East, holds an Executive Program credential from Stanford, and advises longevity projects including One Thirty Labs in Copenhagen. He founded PUORI in 2009 with a single obsession: creating the cleanest third-party tested fish oil on the market. That obsession grew into a full supplement line built on batch testing every finished consumer product for environmental toxins, a standard the industry has yet to catch up to. Together, Dave and Oliver expose the hidden contamination crisis inside the supplement industry, from oxidized fish oil that creates inflammation instead of fighting it, to plant-based protein powders carrying up to 10 times more heavy metals than whey. They break down why organic does not mean safe, how glyphosate embeds itself directly into your collagen infrastructure and disrupts the body's ability to build healthy connective tissue, and why the omega 3 index is one of the most powerful and measurable longevity biomarkers you are probably ignoring. They also dig into the surprising brain optimization and anti-aging benefits of creatine, including new research on concussion recovery and sleep deprivation, and how foundational supplements like vitamin D, magnesium, and high-quality fish oil remain the non-negotiables that no nootropic stack can replace. You'll Learn: Why organic protein powder often contains more heavy metals than non-organic options How glyphosate infiltrates collagen and gets rebuilt into your body's own tissue What the omega 3 index is, why most Americans are dangerously low, and how raising it correlates with years of additional longevity Why plant-based omega 3s fail to convert to DHA and what to take instead How oxidized fish oil creates inflammation rather than reducing it, and what to look for on the label Why vitamin D deficiency persists even with regular sun exposure and how genetics affect your required dose The creatine research that has longevity doctors and neuroscientists paying attention for the first time How foundational supplements support mitochondria, metabolism, and long-term resilience in ways that trendy biohacking stacks cannot replicate What to look for in a clean supplement brand and why third-party batch testing of finished goods is the only standard that matters Thank you to our sponsors! Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Oliver Amdrup-Chamby, PUORI supplements, fish oil oxidation, omega 3 index, heavy metals protein powder, glyphosate collagen, organic protein powder toxins, foundational supplements, creatine brain health, vitamin D deficiency, clean label testing, longevity supplements, biohacking, Dave Asprey, anti-aging, human performance, functional medicine, supplement transparency, plant-based protein heavy metals, whey protein Resources: • Grab a discount on Puori Products by visiting: https://puori.com/pages/dave?dt_id=1750934 • Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 0:00 – Trailer 0:47 – Introduction 2:19 – Foundational vs. Sexy Supplements 4:33 – Omega-3 Index Explained 5:45 – Vegan Omega-3s & DHA 7:39 – Fish Oil Oxidation 8:48 – Batch Testing & Industry Transparency 16:03 – Storing Fish Oil Properly 17:30 – Vitamin D, Magnesium & Fish Oil Stack 19:11 – Vitamin D Dosing & Genetics 21:34 – RDAs & Government Nutrition Advice 23:06 – Glyphosate in the U.S. Food Supply 26:40 – Heavy Metals in Fish Oil 37:44 – Protein Powders & Heavy Metals 45:52 – Creatine for Brain & Concussion 48:48 – TrueDark & Brain Recovery 51:24 – Brain Scanning 53:58 – Toxins in Plant vs. Animal Protein 56:30 – Collagen: Sourcing & Glyphosate Risk 1:02:26 – Outro & PUORI Discount See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What would happen if you did a 5-day sardine fast? Discover the powerful health benefits of sardines, omega-3 fatty acids, and what to expect from this cheap superfood.0:00 Introduction: Eating sardines for 5 days0:52 Sardines nutrition 2:04 Sardine diet: What to expect 5:34 Omega-3 benefits 6:17 Are sardines mercury-safe?7:26 More benefits of omega-3 fatty acids9:03 Sardine fast day 49:49 Taurine in sardines 10:57 Sardine diet results
Pollinators are in serious decline—from monarch butterflies to native bees—and the consequences are profound, and in today's episode, we talk about how you can help—starting right where you are. Specifically, how to create a pollinator sanctuary in your own backyard. Unlike so many global challenges, this is something we can actually impact—right in our own yards, balconies, and communities.In this episode, we talk about:* why pollinators are essential to our food system and ecosystems* the difference between native, non-native, and invasive plants* why some plants support entire ecosystems—and others don't* how to think about your yard as habitat, not decoration* where to start when it all feels overwhelming* how to make changes gradually (without ripping everything out at once)* the role of keystone or “powerhouse” plants