Podcasts about arachidonic acid

Today, I am blessed to have Dr. David Harper here with me. As an educator, researcher, and health consultant, Dr. David Harper has studied the impact of diet on human health for many years. The culmination of that extensive work is the BioDiet, a well-formulated ketogenic plan that works with the body's natural processes to improve health and reverse decades of damage caused by our collective carbohydrate addiction. Dr. Harper and Dale Drewery adopted the BioDiet in 2012 and the weight loss and health improvements they experienced led him to counsel hundreds of people on the Biodiet with similarly consistent and impressive results. Dr. Harper is an associate professor of kinesiology at the University of the Fraser Valley and a visiting scientist at the BC Cancer Research Center, Terry Fox Laboratory. He holds a Ph.D. from the University of British Columbia and completed a post-doctoral fellowship in comparative physiology at the University of Cambridge. He is on the scientific advisory board of the Canadian Clinicians for Therapeutic Nutrition and is a member of the Institute for Personalized Therapeutic Nutrition. In this episode, we cover everything from the potential benefits of ketogenic diets for metastatic breast cancer patients to the intricate workings of the immune system and the therapeutic potential of dietary interventions. Dr. Harper's insights provide a fascinating journey through the complex interplay between diet, metabolism, and disease, offering hope and new perspectives on health and wellness. Tune in as we chat about how ketogenic diets offer a promising therapeutic approach for cancer treatment and neurological conditions by moderating glucose levels, promoting mitochondrial turnover, and enhancing cellular health through AMPK activation and arachidonic acid modulation. Diabetes Method Program: https://diabetesmethod.com/ 

Episode #278. If you follow a plant-based diet, chances are you've wondered if you're getting an adequate amount of omega-3. Join me as I sit down with Professor Philip Calder, an international authority in nutritional immunology with over 20 years of research on fatty acids. Professor Calder helps to cut through the confusion to give you the science-backed breakdown on how these fats impact your health, and how much you should really be consuming. Learn everything you need to know about these essential fats in your diet in this episode. Specifically, we discuss: Introduction (00:00) Philip Calder's Passion for Fatty Acids and His Background (02:00) Debunking Major Fatty Acid Myths in Academia & Social Media (05:53) Altering Cell Membrane Health Through Diet (11:14) Understanding Essential Fats: Why are They Vital? (13:57) Low Conversion Rates: From ALA to EPA & DHA Explained (18:08) The Importance of Monitoring Omega 6 Intake (23:31) The Link Between Omega 6 Fatty Acids and Inflammation (27:28) Does Dietary Linoleic Acid Impact Arachidonic Acid? (35:23) The Inflammatory Role of Arachidonic Acid (37:29) Linoleic Acid & Its Inflammatory Effects (40:41) Should Western Diet Adopters Reduce Omega 6 Intake? (43:56) Major Omega 6 Food Sources and Their Alternatives (45:58) Balancing Omega 3 & Omega 6: Impact on Inflammation (48:57) Plant-Based EPA & DHA: The Genetic Modification Approach (52:04) The Health Implications of Replacing Saturated Fat with Linoleic Acid (59:24) Cardiometabolic Risks of Polyunsaturated Fats (1:03:55) How Omega 3 & Omega 6 Influence Insulin Resistance (1:07:17) Polyunsaturated Fats' Effect on Blood Pressure (1:08:31) The Long-Term Impact of Consuming Polyunsaturated Fats (1:12:05) EPA & DHA Research Variance: Doses, Types, and Outcomes (1:15:40) Ideal Omega 3 Levels for General Health (1:21:51) Benefits of Plant-Based EPA & DHA Supplements (1:27:55) Concerns with Low ALA Levels (1:30:17) Absorption Efficiency of EPA & DHA Supplements (1:32:34) The Science Behind Omega 3 Testing (1:34:28) Algae Oil vs Fish Oil: Which is Superior? (1:36:36) DPA Supplementation and Its Benefits (1:38:33) Does DHA & EPA Supplementation Impact Cholesterol Levels? (1:40:34) Potential Side Effects of DHA & EPA Supplements (1:42:03) Conclusion (1:45:44) Learn more about Professor Philip Calder and his work at southampton.ac.uk/people/5wzh2r/professor-philip-calder. Optimise your health with InsideTracker's biomarker analysis. Get exclusive access to InsideTracker's new ApoB test, and a significant discount at insidetracker.com/simon. Enjoy, friends. Simon Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠Arachidonic Acid Products ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the MSK section. Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message

Dr. Guillermo Escalante - The Science and Application of Fasted vs. Fed Cardio for Fat LossMy Instagram review of his slidesMy fasted cardio biasesDr. Escalante on IGMona Rosene, MS, RD - NAD, Muscle and Athletic Performance: Current Research and Future Needs sponsored by ChromaDexSupplementsConclusionsDr. Scott Forbes - This Will Blow Your Mind - Creatine and cognitionMore on creatine and cognition on the Flex Diet PodcastDr. Forbes on IGWendy Irlbeck, MS, RDN, LD, CISSN - Practical Applications for Fueling Today's Young AthletesMy takeawayWendy on IGAkihito Nishimura, MS - Citocoline - A Potent Brain Health Nutrient and Nootropic sponsored by Kyowa HakkoIs it beneficial in a healthier population?Is it beneficial in a younger population?Dr. Karen Hecht - Astaxanthin as a Dietary Tool for Exercise Training sponsored by AstraRealWhat it is and what it doesMy thoughtsDr. Helena Yardley - The Science of CannabidiolWhere the industry is headedCBD and pain reliefDosingDr. Kirk Escobar - The Evolutionary Inertia of Weight Loss and Body RecompositionChanges in RMR from the stone ageEfficiencyHow to overcome adaptationKatie Emerson, MS RD - nooLVL - A Non-stimulant Nootropic, sponsored by Nutrition 21Katie on IGDr. Jason Cholewa - Caffeine supplementation: What are the effects of CYP1A2 and ADORA2A genes, paraxanthine, and habitual caffeine consumption on resistance exercise and jumping performanceThe researchParaxanthine as a possible new supplementDr. Jason on IGISSN position stand on caffeineDr. Yala Stevens - The Effects of Citrus  Flavonoids on Exercise Performance: an RCT sponsored by Bio ActorSupplementDr. Mark Willems - Anthocyanin-Rich Supplementation: Potential for Sport and Exercise NutritionNew Zealand Black Current researchDr. Brandon Roberts - The Dose-Response Effects of Arachidonic Acid on Primary Human Skeletal MyoblastsFlex Diet Podcast with Dr. RobertsNSAID researchArachidonic acid as a supplementDr. Roberts on IGDr. Jonathan Mike - I Like Big Recovery and I Cannot Lie: Sports Supplements You Can't DenyDr. Mike on IGDr. Lonnie Lowery - Polyphenols as Potential Ergogenic and Body Composition ModulatorsMore than just caffeineDr. Lowery on IGDr. Adam Gonzalez - Citrulline and Resistance Exercise PerformanceTwo formsVasodilationTakeawayDr. Marcas Bamman - Convergence of Exercise Biology and Machine-Learning to Understand Response HeterogeneityPhysiology is a demand-based systemResponders and non-respondersFor a full list of references, check out the Flex Diet Podcast Episode 157 on my website.The Flex Diet Podcast is brought to you by the Flex Diet Certification. Go to https://flexdiet.com/ for 8 interventions on nutrition and recovery.  If you are outside the enrollment window, sign up for the waitlist and you'll be notified when the course opens again. 

Too Much Test Podcast - Episode 6 - Tony Huge & Seth JordanTime Stamps for different topics below.In this episode with speak with Tony Huge and Seth Jordan about a wide range of topics. We cover everything from IGF-1 and Insulin, To Crypto Currencies and Arachidonic Acid.Big THANKS to Tony Huge and Seth Jordan for spending their time with us! They are truly friends of Freedom and the Too Much Test Podcast!!!0:00 Intro1:00 Govt Seized Tony's Website2:35 Forced Jab4:00 Tony's Coof Story8:12 Post Jab Labwork9:45 Tony's Current Gear Protocol10:25 Tony's GH/Insulin Protocol12:00 EA Slin Pills & Insulin Sensitivity19:09 IGF-1 Levels24:23 Gear, Less is more26:30 Human Growth Hormone28:21 S@rm Scheduling34:18 Trenbologna Sandwiches35:45 Cycle Experience Over Time37:10 Teen Gear Exposure from Social Media38:41 Our Next Research Experiments56:39 Myostatin Inhibition60:14 Future Bodybuilding Genetic Evolution & Stem Cells66:43 Amazon Monopoly & Idiocracy68:32 Tesla & Artifical Intelligence70:31 Helium Crypto Decentralized Data Network72:35 Artifical Intelligence & Stem Cells74:57 Petides & Anti Cancer Meds76:20 Monero XMR Untraceable Crypto Coin77:16 Mainstream and Underground Health80:16 Unhealthy Americans & Small Business Lockdowns86:46 TYL Almost went down a health rabbit hole88:36 Small Farms, Micro Nutrients, Curing Cancer89:34 Arachidonic Acid & MGF85:47 OutroTest Your Levels Linkshttps://linktr.ee/testyourlevelsYoutube Channel - https://www.youtube.com/channel/UC-xAd1-SQ6ooGpXiu_Uln6wInstagram - https://www.instagram.com/testyourlevels/TikTok - https://www.tiktok.com/@testyourlevels?Sam Stolts Linkshttp://bit.ly/sam-stolt-linksYoutube Channel - https://www.youtube.com/channel/UCAOWpCd7-DhAGs8BR3y8_HQInstagram - https://www.instagram.com/sam.stolt/TikTok - https://www.tiktok.com/@sam.a.stolt?David Demesquita Linkshttps://taplink.cc/dynamite_dYoutube Channel - https://www.youtube.com/channel/UCxjheFb2GYN1iHdPgFjzwCQInstagram - https://www.instagram.com/dynamite_d/#TonyHuge #TonyHugePodcast #BodybuildingPodcast

Dr Doug Bilbus introduction and backgroundA brief primer of essential fatsMortality and fish oilRecommended amounts for health benefitsSport supplementationCOVID, clinical trials, inflammation, and fish oilDHA and arachidonic acid in membranes and athletes (and sled dogs)Cold exposure can help convert more DHAHibernating animalsCan you get too much EPA and DHA?Farm-raised salmon EPA and DHA quite low?2-3g DHA and EPA science-backed recommendationOmega 3 blood testing (omega3test.com)Find Dr. Bilbus at lipidlab.com and omega3test.comGo to omega3test.com for a special offer - limited time only. Type code FLEXDIET.The Flex Diet Podcast is brought to you by the Flex Diet Certification. Go to flexdiet.com for 8 interventions on nutrition and recovery. Join the waitlist, which puts you on the daily newsletter, and you’ll be the first to be notified when the certification opens again.  

Hear about Brent's backgroundResearch on fish oil- where it's been and where it's goingOmega 3 to Omega 6 ratiosOmega 3 index: what it is and what it tells youThe form of supplementation mattersWhat to look for on a supplement labelCan you hyper dose fish oil to catch up on a deficiency?Algae-based fish oilNew study outline and detailsArachidonic acidBrent's recommendationsFind Brent at brent@omega3study.com or on LinkedIn.The Flex Diet Podcast is brought to you by the Flex Diet Certification. Enrollment opens Jan. 11, 2021 for the next seven days. Go to flexdiet.com to enroll and get access to interventions on nutrition and recovery. If you're listening after enrollment closes, join the waitlist, which puts you on the daily newsletter, and you’ll be the first to be notified when the certification opens again.

Question: How does someone get arachidonic acid and choline without eggs and liver? So apart from liver and egg yolks, I think that it is very difficult to get enough arachidonic acid from food. Yes, GLA might help, but there's actually arachiodonic acid supplements. And for the vegans out there, I don't know if the production process is strictly vegan, but they are derived from a specific mushroom and you can get them on Amazon. So I think supplementing with arachidonic acid is probably the most direct way to do that. And then evening primrose or a barrage oil could help provide precursors to arachidonic acid.This Q&A can also be found as part of a much longer episode, here.  If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. There are two ways to discuss this episode: Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss  If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard. DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Question: How do I bring up low levels of arachidonic acid? Should I supplement with 250 milligrams? What brand is there from well-known company?   If you want 250 milligrams of arachidonic acid, eat an egg. I don't know anything about arachidonic acid supplements yet, except that they exist because you can eat eggs and you'll get plenty. Do you want to try the supplement? Well you can, but I don’t think it’s necessary.    You eat two eggs a day already, so eat four.    The oxidative stress and inflammation will consume the arachidonic acid, so look at that too.   This Q&A can also be found as part of a much longer episode, here: https://chrismasterjohnphd.com/podcast/2019/02/24/ask-anything-nutrition-feb-17-2019/   If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up with a 10% lifetime discount here: https://chrismasterjohnphd.com/q&a

Mark reads from arachidonic acid to Arapaho. The word of the episode is "Arapaho". dictionarypod@gmail.com https://www.facebook.com/thedictionarypod/ https://twitter.com/dictionarypod https://www.patreon.com/spejampar 917-727-5757

3:30 Georgi's story/background 6:25 Georgi's venture into low carb/Paleo 8:20 Georgi's problems with low carb begin 10:50 How Coke led Georgi to Ray Peat 14:20 Georgi goes back to high sugar 17:40 Burnout Syndrome is due to high cortisol 19:05 Mainstream medicine's “car” view of the organism: Energy & Structure are “separate" 20:51 Metabolic Theory: Energy & Structure are INTERDEPENDENT 21:24 Stress is a functional disorder 22:06 No single gene mutation is responsible for all disorders around us (Diabetes, Cancer, Alzheimers, Schizophrenia, Other Lethal Diseases etc;) 22:41 Metabolic theory: All of these diseases are due to chronic interference of energy (ATP & C02) 23:11 How Fatty Liver disease can lead to cancer without any change or mutation in genome 23:51 Metabolic Theory: Chronic Interference with energy lead to structural derangements 24:18 Energetic disturbances are produced in the entire body, not specific cells 24:30 Cells communicate chemically and electromagnetically 24:37 Knee problem will be known by entire organism 25:30 Ray Peat's definition of stress 26:12 Temperature and pulse should be used together 26:38 Waking Armpit Temperature Below 85 is a problem thyroid; testosterone & progesterone have positive inotrophic & chronotrophic effects on heart 26:57 Achilles Tendon Reflex Test: a test for hypothyroidism, dementia, and all cause mortality 28:31 Urine Test as measure of metabolic rate 29:41 Are competitive athletes healthy? 31:57 Danny's gasp ;p 32:51 The amazing recuperative abilities of children 35:10 Inefficient energy production leads to poor repair processes, shutting down of organs, and cancerization 35:33 What is cancer? 36:49 Protective hormone synthesis requires energy 37:16 High cholesterol: A sign of hypothyroidism and hormone synthesis impairment 37:30 Extreme situations of stress & extreme aging's hormone production & their effects 39:37 Inflammation explained: The true cause of illness of all chronic and infectious diseases 40:40 No such thing as healthy inflammation 41:06 Arachidonic Acid as a major precursor to Inflammation in the body 42:07 PUFA's affect on cell's affinity for water 42:44 Signals for cell division and growth. 43:30 What results in mutations? Genes or cellular metabolic derangements? 43:45 PUFA's key signal effects, PUFA's effects 46:42 EPA and DHA (Unsaturated) as precursors for lipid peroxidation, DHA as substrates for acrolein: Universally agreed upon aging and inflammatory processes 48:23 Omega 3 Propaganda and background 50:12 FDA reviews original evidence for saturated fat and reverses opinion 52:18 All gut bacteria capable of producing endotoxin is harmful 56:41 How antibiotics kill bacteria 57:40 Serotonin and endotoxin's place in stress system, more on its effects and processes 59:25 Serotonin's functional roles +more

Because we’ve demonized the use of anabolics for cosmetic purposes, there’s a lot of it being sold on the black market— much of which isn’t legitimate. What are some of the worst compounds to take from an unreliable source? Why is arachidonic acid such an important nutrient for performance? On this episode, I’m joined by author, scientist and anabolics expert, Bill Llewellyn, to discuss these questions and more. Aside from protein, arachidonic acid is the most important nutrient in training and performance. -Bill Llewellyn     Three Takeaways Only ⅓ of the anabolic products sold on the gray market are actually legitimate. Testosterone cypionate vs. testosterone enanthate when it comes to legitimacy: 35% of cypionate samples were legit while enanthate was legitimate over 70% of the time. Arachidonic acid is a natural anabolic. It can help facilitate growth and muscle recovery, and it can help you break through plateaus. At the start of the show, Bill talked about how he got started and why the demonization of anabolic steroids is a farce. Next, we talked about the work Bill’s company is doing in creating a test for growth hormone. We also talked about what percentage of the compounds on the market are actually legit.   We also discussed; The best compounds according to label claim How hard it is to tell the difference between the real stuff and the fake stuff The power of supplementing arachidonic acid The medicinal, life-enhancing and restorative qualities of anabolics and testosterone are incredible. Yet in order for patients to see these benefits, they need to be getting legitimate products in the first place. That’s why it’s so important to educate people on the right products and how to get them through legitimate channels to avoid harm or wasting money on glorified placebos.   Guest Bio- Bill is an author and scientist in the field of human performance enhancement. He is also the founder of Molecular Nutrition. His books include the Anabolics Book and the Sports Supplements Reference Guide. Find him on Facebook https://www.facebook.com/AuthorWL/.

Opening chat: What do we mean by nutrient synergy?Topics:1. 00:00 -- Introducing Diane, Liz, and the Show (Diane and Liz chit chat)2. 02:30 -- Introducing Nutrient Synergy and Me3. 04:40 -- Oops the mute button was on!4. 05:30 -- My Background/Story5. 09:12 -- What I Ate Before and After My Recover From Vegetarianism6. 13:00 -- Even Chris Masterjohn Was Once Afraid of Cholesterol7. 13:30 -- Plugging My Stuff8. 14:59 -- Synergy Question 1: Why B12 Supplements, Especially Cyanocobalamin, Can't Replace Animal Foods (And why we want bones and skin in there too!)9. 21:12 -- The Nose-to-Tail Experience: The Synergy Between Frugality, Ecological Consciousness, Humane Treatment of Animals, and Health (you mean that skinless boneless chicken breast is supposed to have a chicken attached to it?)10. 24:20 -- Synergy Question 2: Is Liver Toxic? Synergy Between Vitamins A, D, and K11. 34:42 -- Could the Vitamin D Craze Be Causing Problems? (Yes!)12. 37:30 -- What Happens When "Too Much" Is a Lower Dose Than "Enough"?!13. 40:31 -- Cod Liver Oil14. 44:57 -- Synergy Question 2: Arachidonic Acid and DHA, Harms of Too Much EPA15. 48:25 -- Foods for Preventing Flu, Then Goodbye!  

What causes pain and how do we stop it? This unit looks at how the human body responds to the release of certain chemicals and as a result feels pain. Pain can be reduced by inhibiting the formation of such chemicals and you will learn how the molecular structure of aspirin has been formulated to help in this process. This study unit is just one of many that can be found on LearningSpace, part of OpenLearn, a collection of open educational resources from The Open University. Published in ePub 2.0.1 format, some feature such as audio, video and linked PDF are not supported by all ePub readers.

Background/Aim: N-6 fatty acids are considered to promote diseases prevalent in industrialized countries and characterized by an increased eicosanoid biosynthesis from arachidonic acid (AA). We investigated the impact of the linoleic acid (LA) intake on AA levels in humans. Methods: Six healthy female volunteers (age range 2334 years) were given liquid formula diets (LFD) devoid of AA for 6 weeks, providing a constant intake of zero energy% (LFD 0: protein 15%, carbohydrates 85%) or 20 energy% (LFD 20: protein 15%, carbohydrates 55%, fat 30%) LA, for 3 weeks each. Fatty acids of plasma cholesteryl esters and platelet lipids were determined each week, and the prostaglandin biosynthesis was measured in 24-hour urine samples. Results: LFD 0 increased (+31% of initial value) and LFD 20 lowered (-30% of initial value) the percentage of AA in plasma cholesteryl esters and platelet lipids. Moreover, absence of dietary AA lowered the percentages of AA in plasma (-31% week 0 vs. week 6) and platelet (-11%) lipids, indicating a low transformation of LA. LFD 0 reduced urinary metabolite levels of prostaglandins D, E, and F in 24-hour urine samples (-48%, p < 0.001) within 24 h, but did not significantly affect platelet aggregation (-10%) and thromboxane formation (-25%). LFD 20 significantly lowered platelet aggregation (-25%) and thromboxane formation (-43%). The prostaglandin metabolite levels increased during the first 10 days, declined thereafter, and were lower than the preexperimental values at the end of the 3-week period. Conclusions: The results show that dietary LA does not increase the AA levels in plasma or platelet lipids and does not persistently contribute to prostaglandin biosynthesis which is increased by AA intake with Western diets.