Component of blood aiding in coagulation
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Got a story idea for Bloodworks 101? Send us a text message At Bloodworks, we like to say that platelets are "golden." Why? well, as Bloodworks 101 producer John Yeager found out, it's because they have such an impact on the people who receive them. But it's also because of the time and sacrifice it takes to produce them. For this edition, John spoke to Bloodworks' Senior Product Strategy Manager Kyle Boynton.
TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Ann Palmenberg dies (Cress) Ann at Chumakov Symposium (YouTube) Unknown illness in Congo (NY Times) Bad news about mpox outbreak (NPR) US interrupts Ebola prevention program (NPR) First measles death in Texas (Texas Trib) Flu vaccine selection meeting canceled (NY Times) US ends funding for polio, HIV, malaria and more (NY Times) Clade 2.3.4.4b H5N1 neuraminidase has a long stalk (mBio) Predictors of durable antibody responses to vaccines (Nat Immunol) Review of adjuvants (Vaccinol Methods Vacc Res) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Video of the Northern Lights from Space Rich – Vaccination for Sudan Ebola virus disease Alan – Specialized moth wing scales give it 3-D camouflage (news and paper) Vincent – WHO Recommendations for Influenza Vaccine Composition for the 2025-2026 Northern Hemisphere Influenza Season Listener Picks Gerry – Eukaryotic Transcription Anne – The science of the solar system Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.
CME credits: 1.00 Valid until: 31-01-2026 Claim your CME credit at https://reachmd.com/programs/cme/fetalneonatal-alloimmune-thrombocytopenia-fnait-the-platelet-equivalent-of-rh-disease/32275/ Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can lead to substantial medical challenges for the mother, fetus, and neonate. Diagnosis is often difficult without low platelet counts or frank bleeding. But a mother's risk for FNAIT can be assessed, and existing and newly emerging therapies can act as preventive measures and improve fetus/neonate outcomes. Join Drs. Karin Blakemore and Emilie Vander Haar as they address many of the issues surrounding the management of FNAIT and offer clear and actionable suggestions for you to bring into your clinical practice.
In this episode, Dr. Joseph Purita, Medical Director at PUR-FORM & Regenerative Medicine Pioneer, discusses the intricate relationship between inflammation and aging, emphasizing the importance of lifestyle choices, dietary habits, and supplements in promoting longevity. He explains the concept of immunosenescence and how it contributes to chronic inflammation, which is a significant factor in many diseases. He and Dr. Anthony Balduzzi also cover the role of regenerative medicine in treating conditions like arthritis and the potential of various supplements to enhance health and well-being. Dr. Purita explains various regenerative medicine techniques, including PRP, stem cells, peptides, and gaseous therapies like hyperbaric oxygen and ozone. He emphasizes the importance of light therapy in enhancing healing and the role of peptides in recovery. The discussion also touches on the future of personalized medicine, highlighting the potential impact of AI and the need for a healthier culture.Key TakeawaysInflammation is a key factor in aging and disease.Immunosenescence refers to aging immune cells that contribute to inflammation.A healthy lifestyle, including exercise and diet, is crucial for longevity.Intermittent fasting can be an effective strategy for health.Olive oil and a Mediterranean diet are beneficial for reducing inflammation.Urolithin A enhances mitochondrial health and function.Regenerative medicine can improve joint health but cannot reverse aging.Exercise is the most effective medicine for overall health.Dietary choices significantly impact inflammation and health outcomes.Supplements can support health but should complement a healthy lifestyle. Prolotherapy creates local inflammation to enhance healing.Platelet-rich plasma (PRP) releases growth factors essential for healing.Stem cells are part of a larger symphony of regenerative cells.Photobiomodulation uses light therapy to benefit cellular health.Peptides like BPC 157 and TB 500 can enhance healing processes.Hyperbaric oxygen therapy increases oxygen delivery to tissues.Ozone therapy can help reduce inflammation and viral load.Hydrogen therapy acts as a potent antioxidant and anti-inflammatory.AI will play a significant role in the future of personalized medicine.The goal is to increase health span, not just lifespan.Where to learn more about PUR-FORMWebsite: https://purformhealth.com/Instagram: https://www.instagram.com/purformhealth/Facebook: https://www.facebook.com/purformhealth/TikTok: https://www.tiktok.com/@purformhealthBiographical Information on Dr. Joseph PuritaDr. Joseph Purita is a pioneering expert in Regenerative Cell and PRP therapy for orthopedic conditions. After graduating from Georgetown University Medical School, he completed his surgical internship at the University of Florida Medical Center. He then completed his orthopedic surgery residency at the University of Miami-Jackson Memorial Hospital, where he served as the Chief Administrative Resident.Since joining the Boca Raton Orthopedic Group (BROG) in 1981, Dr. Purita has established himself as a leader in the field of orthopedic surgery and regenerative medicine. He currently serves as Chief Medical Officer at PUR-FORM in Boca Raton. A globally recognized authority, Dr. Purita trains...
In this episode, Dr. Joseph Purita, Medical Director at PUR-FORM & Regenerative Medicine Pioneer, discusses the intricate relationship between inflammation and aging, emphasizing the importance of lifestyle choices, dietary habits, and supplements in promoting longevity. He explains the concept of immunosenescence and how it contributes to chronic inflammation, which is a significant factor in many diseases. He and Dr. Anthony Balduzzi also cover the role of regenerative medicine in treating conditions like arthritis and the potential of various supplements to enhance health and well-being. Dr. Purita explains various regenerative medicine techniques, including PRP, stem cells, peptides, and gaseous therapies like hyperbaric oxygen and ozone. He emphasizes the importance of light therapy in enhancing healing and the role of peptides in recovery. The discussion also touches on the future of personalized medicine, highlighting the potential impact of AI and the need for a healthier culture.Key TakeawaysInflammation is a key factor in aging and disease.Immunosenescence refers to aging immune cells that contribute to inflammation.A healthy lifestyle, including exercise and diet, is crucial for longevity.Intermittent fasting can be an effective strategy for health.Olive oil and a Mediterranean diet are beneficial for reducing inflammation.Urolithin A enhances mitochondrial health and function.Regenerative medicine can improve joint health but cannot reverse aging.Exercise is the most effective medicine for overall health.Dietary choices significantly impact inflammation and health outcomes.Supplements can support health but should complement a healthy lifestyle. Prolotherapy creates local inflammation to enhance healing.Platelet-rich plasma (PRP) releases growth factors essential for healing.Stem cells are part of a larger symphony of regenerative cells.Photobiomodulation uses light therapy to benefit cellular health.Peptides like BPC 157 and TB 500 can enhance healing processes.Hyperbaric oxygen therapy increases oxygen delivery to tissues.Ozone therapy can help reduce inflammation and viral load.Hydrogen therapy acts as a potent antioxidant and anti-inflammatory.AI will play a significant role in the future of personalized medicine.The goal is to increase health span, not just lifespan.Where to learn more about PUR-FORMWebsite: https://purformhealth.com/Instagram: https://www.instagram.com/purformhealth/Facebook: https://www.facebook.com/purformhealth/TikTok: https://www.tiktok.com/@purformhealthBiographical Information on Dr. Joseph PuritaDr. Joseph Purita is a pioneering expert in Regenerative Cell and PRP therapy for orthopedic conditions. After graduating from Georgetown University Medical School, he completed his surgical internship at the University of Florida Medical Center. He then completed his orthopedic surgery residency at the University of Miami-Jackson Memorial Hospital, where he served as the Chief Administrative Resident.Since joining the Boca Raton Orthopedic Group (BROG) in 1981, Dr. Purita has established himself as a leader in the field of orthopedic surgery and regenerative medicine. He currently serves as Chief Medical Officer at PUR-FORM in Boca Raton. A globally recognized authority, Dr. Purita trains surgeons in...
The use of assistive devices when treating unruptured aneurysms is widespread in neurointerventional practice. But there is no standard for how long patients should receive dual anti-platelet therapy after the procedure, to protect them from thrombotic complications. Durations can range from one month to one year. This episode looks at a review of patient data across 12 locations to understand the effect of therapy duration on risk of complications. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Andrew Ringer¹, first author of the paper: Impact of duration of dual anti-platelet therapy on risk of complications after stent-assisted coiling of unruptured aneurysms 1. Mayfield Clinic, Cincinnati, Ohio, USA Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.
Dr Robert-Jan de Vos, sports physician and associate professor at Erasmus Medical Centre in Rotterdam, The Netherlands, dives deep into all things Achilles tendinopathy. In part 2 of this series, Dr de Vos covers the multitude of options for treatment, outside of exercise therapy. Should you and the patient consider corticosteroid injections, PRP injections, heel lifts, shockwave, NSAIDs, or surgery? And when? What are the important clinical considerations when patients choose these options? Part 2 has it all! ------------------------------ RESOURCES Terminating corticosteroid injection in tendinopathy? https://www.jospt.org/doi/10.2519/jospt.2023.11875/ Dutch multidisciplinary guideline on Achilles tendinopathy: (https://pubmed.ncbi.nlm.nih.gov/34187784/ Platelet-rich plasma injection for chronic Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/20068208/ Time to put down the scalpel when treating tendinopathy? https://pubmed.ncbi.nlm.nih.gov/31653777/ Why tendons like load: https://pubmed.ncbi.nlm.nih.gov/29920664/ Clinical diagnosis of Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/34692248/ Clinical tool for identifying spondyloarthropathy: http://tinyurl.com/3my87hma More on the pain monitoring model: https://pubmed.ncbi.nlm.nih.gov/17307888/ Dosing your resistance training in tendinopathy: https://pubmed.ncbi.nlm.nih.gov/37169370/ Best treatment for Achilles tendinopathy (living systematic review): https://pubmed.ncbi.nlm.nih.gov/32522732/ Achilles Pain, Stiffness, and Muscle Power Deficits - 2024 updated clinical practice guideline: https://www.jospt.org/doi/10.2519/jospt.2024.0302
In this week's episode, unravelling follicular lymphoma subtypes. Researchers dissect the biological diversity of follicular lymphoma and introduce a new prognostic mode, that could change the way this B-cell neoplasm is subtyped and treated. Then, concerning stroke rate trends in sickle cell disease. A new report shows increasing rates of cerebrovascular events among people with SCD in California. Finally, procoagulant platelet activation promotes venous thrombosis. Investigators report finding procoagulant platelets in the circulation and in thrombi of patients and mice with DVT or PE. Featured Articles:Follicular lymphoma comprises germinal center–like and memory-like molecular subtypes with prognostic significanceRates of strokes in Californians with sickle cell disease in the post-STOP eraProcoagulant platelet activation promotes venous thrombosis
Join us for an in-depth conversation with William V. Giannobile, interviewed by Sejal Thacker, as he reflects on his key publication, Platelet-derived growth factor stimulates bone fill and rate of attachment level gain. Giannobile discusses the groundbreaking development of recombinant human platelet-derived growth factors (PDGFs) and their pivotal role in oral tissue regeneration. He traces PDGF's journey from discovery to clinical application, sharing insights into the science, trials and regulatory steps that brought this innovation to patients. From early tissue culture studies to regenerative therapies for periodontal disease, Giannobile details the research process and rigorous trials required to develop safe and effective treatments. This is a must for anyone interested in the latest developments in oral tissue regeneration!
Top Sports Medicine Articles Podcast – PRP vs. Steroid Injections for Tennis Elbow Dr. Moira Davenport discusses the #8 article of 2023, “Corticosteroid Injections for the Treatment of Lateral Epicondylitis are Superior to Platelet-rich Plasma at 1 Month but Platelet-rich Plasma is More Effective at 6 Months: An Updated Systematic Review and Meta-analysis of Level 1 and 2 Studies,” which was originally published in The Journal of Shoulder and Elbow Surgery in September 2023. Dr. Jeremy Schroeder serves as the series host. Dr. Davenport is a member of the AMSSM Top Articles Subcommittee, and this episode is part of an ongoing mini journal club series highlighting each of the Top Articles in Sports Medicine from 2023, as selected for the 2024 AMSSM Annual Meeting. Corticosteroid Injections for the Treatment of Lateral Epicondylitis are Superior to Platelet-rich Plasma at 1 Month but Platelet-rich Plasma is More Effective at 6 Months: An Updated Systematic Review and Meta-analysis of Level 1 and 2 Studies https://www.jshoulderelbow.org/article/S1058-2746(23)00395-6/abstract
Hannah's facebook status from sixteen years ago today was this ... "Hannah is enjoying being home after the annoying day of another platelet transfusion."Hannah rarely complained, so this expression of annoyance revealed a lot about how she felt about platelet transfusions. She had battled platelet issues off and on throughout the early months of her treatment, and once again, low platelets were becoming an ongoing problem.Thank you for joining me for another bonus episode of the While We're Waiting podcast in this year-long series in which I share our family's experiences as our teenage daughter Hannah battled glioblastoma brain cancer from February 2008 through February 2009. My desire is to process through the events of those twelve months with the perspective that 16 years has brought … and point listeners to hope in Jesus along the way.I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org
In this week's episode, we'll learn about the role of a platelet-specific glycoprotein receptor in abdominal aortic aneurysm formation, the influence of TP53 mutations on outcomes for patients with 5q-deleted myelodysplastic syndrome, and a rational combination treatment intended to produce more durable responses in patients with refractory B-cell acute lymphoblastic leukemia who are treated with CAR T-cell therapy.Featured Articles:Soluble glycoprotein VI predicts abdominal aortic aneurysm growth rate and is a novel therapeutic targetInfluence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletionA phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia
In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Dong Chen, M.D., Ph.D., chair of the Division of Hematopathology in the Department of Laboratory Medicine and Pathology at Mayo Clinic. They discuss rare and inherited platelet disorders and esoteric laboratory testing of hematologic disorders.Specific topics of discussion include:How these rare disorders are diagnosed through laboratory tests.Why platelet transmission electron microscopy is considered the gold standard for diagnosing disorders like Hermansky Pudlak syndrome, Wiskott-Aldrich syndrome, Chediak Higashi syndrome, and Jacobson/Paris-Trousseau syndrome.The process involved with developing and validating the PTEM test (Mayo ID: PTEM) at Mayo Clinic.The importance of ongoing research and advocacy to enhance care for patients with rare platelet disorders.
Send us a textIn this episode, we discuss the epidemiology, clinical manifestations, investigations and treatment of ITP. Our medicine minute discusses the Harrington-Hollingsworth Experiment. Written by: Dr. Vanessa Giuliano (Internal Medicine Resident)Reviewed by: Drs. Taylor Dear and Zachary Liederman (Hematology) and Dr. Kevin Venus (General Internal Medicine)Infographic by: Dr. Lilly Yu (Internal Medicine Resident)Support the show
In this episode, Dr. Rohrich is joined by Dr. Sam Lynch to discuss what's new in PDGF.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter dives deep into the topic of hair loss, exploring its relationship with aging and its impact on quality of life. The conversation focuses on androgenic alopecia, the most common form of hair loss in both men and women, and covers the differences in patterns and causes between the sexes. Peter delves into the right timing for treatment, breaking down various options such as minoxidil and finasteride, low-level laser therapy, platelet-rich plasma injections, and more. Additionally, Peter outlines the pros and cons of the two primary hair transplantation methods and concludes with practical advice on selecting the right specialist or treatment team for those facing hair loss. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #63 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: The impact of hair loss on emotional health [2:15]; The prevalence, patterns, and causes of hair loss in men and women [5:15]; The genetic and hormonal causes of hair loss, and the role of dihydrotestosterone (DHT) in androgenic alopecia [8:45]; The visual differences in hair loss patterns between men and women, and the importance of consulting a specialist to rule out non-genetic causes of hair loss [13:30]; How genetic predisposition influences the risk of androgenic alopecia, and how early detection through diagnostic tools and blood tests can help manage risk more effectively [16:45]; Ideal timing for starting treatment: why early treatment is crucial for effectively managing hair loss [19:30]; The various FDA-approved treatments for androgenic alopecia, their mechanisms, and additional off-label treatments commonly used to manage hair loss [24:30]; Topical minoxidil—the most commonly recommended starting treatment for hair loss [30:15]; Oral vs. topical minoxidil: efficacy, ease of use, and potential side effects that must be considered [33:45]; Finasteride for treating hair loss: efficacy, potential side effects on libido, and the need for careful PSA monitoring in men to avoid missing early signs of prostate cancer [37:15]; Other effective hair loss treatments for women: boosting hair density with spironolactone gel and ketoconazole shampoo as part of a comprehensive strategy [41:30]; Low-level laser therapy: effectiveness, costs, practicality, and a comparison of in-office treatments with at-home devices [49:00]; Platelet-rich plasma (PRP) as a treatment for hair loss: potential effectiveness, varying protocols, and significant costs [53:45]; Hair transplant for advanced hair loss: criteria and considerations [58:00]; Types of hair transplants: follicular unit transplantation (FUT) vs. follicular unit extraction (FUE) [1:02:00]; The financial cost of hair transplant surgery, and what to consider when seeking affordable options [1:06:15]; The potential risks and downsides of the various hair transplant procedures [1:09:30]; Post-procedure care for hair transplants and whether the procedure must be repeated periodically [1:16:30]; Combining different hair loss treatments: benefits, risks, and considerations [1:18:30]; Emerging hair loss treatments with limited data [1:21:00]; Key considerations for selecting the right treatment plan for hair loss [1:22:00]; A summary of the different considerations for men and women facing hair loss [1:24:30]; Practical advice on selecting the right specialist or treatment team [1:26:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
In this week's episode we'll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome.Featured Articles:Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma Platelet-derived TGF-β1 induces functional reprogramming of myeloid-derived suppressor cells in immune thrombocytopenia Phase 3 randomized trial of mavorixafor, CXCR4 antagonist, in WHIM syndrome
If I had known how important platelets were going to become in the life of our family, I probably would have paid closer attention in my junior high science class! Sixteen years ago today, Hannah's bloodwork showed a continued downward trend in her platelet levels, leading to the postponement of her next chemotherapy treatment. While Hannah was happy about that, we were anxious to get back on track with her therapy. Today's bonus espiode describes the mixed emotions of that time. Thank you for joining me for another bonus episode of the While We're Waiting podcast in this year-long series in which I share our family's experiences as our teenage daughter Hannah battled glioblastoma brain cancer from February 2008 through February 2009. My desire is to process through the events of those twelve months with the perspective that 16 years has brought … and point listeners to hope in Jesus along the way.I would love to hear your thoughts on the show. Click here to send me a message!All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org
Today, we explore a groundbreaking research paper published in JCI Insight by Ma and colleagues in June 2020, titled “Platelet factor 4 is a biomarker for lymphatic-promoted disorders.” The study, which included contributions from Dr. Stanley Rockson at Stanford University and Dr. Guillermo Oliver at Northwestern, aimed to identify a biomarker for lymphatic dysfunction and improve the diagnosis of lipedema, further confirming that lipedema is a lymphatic disorder.
Growth Factors, Exosomes, Biohacking - Join us in this week's podcast where we sit down with Dr. Samuel Lynch, an accomplished scientist, inventor, and CEO of Ariessence! Dr. Lynch introduces us to his groundbreaking product, Ariessence Pure PDGF+, a platelet-derived growth factor used in aesthetic applications. He shares his journey from a decade of lab research to pioneering biotech innovations and discusses the rigorous process of developing FDA-approved products. We delve into the unique benefits of recombinant DNA technology, talking about how Ariessence accelerates wound healing, reduces downtime post-procedures, and enhances skin health by promoting collagen and blood supply. Dr. Lynch also explains how Ariessence can work faster than PRP due to its higher concentration, making it a great alternative to use after a microneedling treatment. We touch on the differences between growth factors and exosomes, biohacking trends, and where we see the future of regenerative medicine heading. Tune in to learn about the revolutionary potential of Ariessence in the field of aesthetics!
Are you experiencing bedroom blues and struggling to rise to the occasion? Erectile dysfunction (ED) can be a frustrating issue for men. If you're affected by ED, there may be a new treatment option you haven't heard of yet. Platelet-rich plasma (PRP) therapy uses your own blood, your platelets, to potentially improve your erectile function. In this episode, I will explain what PRP therapy is and how it works. I'll also discuss the possible benefits of this treatment. Listen now to find out if it could be right for you!--------------If you liked this episode, please SUBSCRIBE, like, leave a comment, and share so we can keep bringing you valuable content that gets results!--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://sexualhealthformenpodcast.com/platelets-restore-erectile-function--------------Ready to empower your health journey? Secure your FREE PDF copy of the “5 Natural Solutions to Overcome ED” today! Dive into knowledge that could transform your life. Click the link below to claim your copy
Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today's episode, Karine Carrière will explain further what are microvesicles, their importance in coagulation and how to analyze them. Literature sources: [Tesselaar et al.], [Lacroix et al.] [Faille et al.] [Mullier et al.] Vallier et al.] . [Nieuwland et al.] Kim HK, Song KS, Park YS, Kang YH, Lw YJ, Lw KR, et al. Elevated levels of circulating platelet microparticles, VEGF, 11-6 and FiANTES in patients Wlth gastrlc cancer. possible mle of a metastasis predlotor. Eur J Cancer 2003;39(2):184-91. Helley D, Banu E, Bouziane A, Banu A, Scotte F, Fiher AM, et al. Platelet microparticles: a potential predictive factor of survival in hormone-reac pmstate cancer patients treated with docetaxel-based chemotherapy. Eur Urnl2009;56(3):479-84. Zwicker JI, Liebman HA, Neuberg D, Lecmix R, Bauer KA, Furie BC, et ai. Tmr-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res 2009; 15 (22): 68630-40 Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.
Zach, Emily, Mo & Mayes Would you bargain hunt for a medical procedure? Or is that one area where you want to pay for quality? Zach had a shouting match this morning over literal dog poop. Hacks had an EXCELLENT season finale and is a contender for show of the year. We break down temperature like a Katy Perry song. Would you rather be Hot or Cold? The dos and donts of meeting your significant other's parents. Patreon Exclusive: Are corn dogs and beef wellingtons basically the same thing? COUNT THE DINGS MERCH STORE - Check it out here: https://bit.ly/CTDMERCH Sign up for Underdog Fantasy Promo Code DING: https://play.underdogfantasy.com/p-count-the-dings If you want to hear the full Mailbag, check out the Patreon! Join the Count The Dings Patreon for exclusive full, ad free episodes, extra Cinephobe content and more at www.patreon.com/CountTheDings Watch the Mailbag on YouTube: https://www.youtube.com/@CountTheDings Learn more about your ad choices. Visit megaphone.fm/adchoices
Platelet-rich plasma (PRP) therapy is making headlines in the field of fertility, with ovarian PRP emerging as a promising approach for women facing certain egg quality challenges. This type of treatment involves injecting a woman's own platelet-rich plasma into her ovaries. PRP is a concentration of platelets and growth factors created from a patient's own blood. These growth factors can stimulate cellular regeneration and may help to improve ovarian function and increase IVF success. Its been used for decades in the beauty industry, hair growth and in healing a variety of conditions. Why not try it for fertility as well?! Dr. Jesse Hade, MD, REI and his colleagues at Generation Next Fertility Center in NYC conducted a study to assess just that. They found that this therapy may be particularly beneficial for women experiencing premature ovarian failure or diminished ovarian reserve, conditions that impact the quantity and quality of eggs available for fertilization. Ovarian PRP is also being explored as a treatment option for women who have had poor responses to IVF cycles.Tune in as we are joined by Dr. Jesse Hade, MD, REI - a compassionate board-certified reproductive endocrinologist with over two decades of private practice experience, is a leading expert in fertility and has earned numerous awards for his research. Is Ovarian PRP right for you? Listen in and find out! You'll Learn: What Ovarian PRP treatment is How PRP treatment is beneficial for fertility Who can benefit from this treatment Thanks so much for listening to our podcast! If you enjoyed this episode and think others would love to hear it, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode or want to be a guest on the show? Leave a comment in the section below or visit the website to contact me!www.naturnalife.comSubscribing to The Podcast:If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts, Stitcher, Spotify, Amazon, or whatever your favorite podcast app is!Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. So if you have a minute, please leave a review on Apple Podcasts!
By April 19, 2008, Hannah had been undergoing radiation treatments five days a week and taking an oral chemotherapy drug daily since mid-March. The intensity of these ongoing treatments was finally beginning to take a toll, as you will hear from the email update I sent on this date sixteen years ago ...Thank you for joining me for another bonus episode of the While We're Waiting podcast in this year-long series in which I share our family's experiences as our teenage daughter Hannah battled glioblastoma brain cancer from February 2008 through February 2009. My desire is to process through the events of those twelve months with the perspective that 16 years has brought … and point people to hope in Jesus along the way.All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org
Dr. Scott Paradise continues the countdown and reviews articles No. 5 and No. 4 of 2022 on this episode of the Top Sports Medicine Articles podcast, which is hosted by Dr. Jeremy Schroeder. The first article is the #5 article, “Platelet-rich Plasma Injection vs. Operative Treatment for Lateral Elbow Tendinosis: A Systematic Review and Meta-analysis,” which was originally published in the Journal of Shoulder and Elbow Surgery in February 2022. The second article was selected as the #4 of 2022, examining the “Outcomes of Athletes With Genetic Heart Diseases and Implantable Cardioverter-Defibrillators Who Chose to Return to Play,” which was originally published in the Mayo Clinic Proceedings in November 2022. Dr. Paradise is a member of the AMSSM Top Articles Subcommittee, and this episode is part of an ongoing mini journal club series highlighting each of the Top Articles in Sports Medicine from 2022, as selected for the 2023 AMSSM Annual Meeting in Phoenix, AZ. Platelet-rich Plasma Injection vs. Operative Treatment for Lateral Elbow Tendinosis: A Systematic Review and Meta-analysis DOI: doi.org/10.1016/j.jse.2021.09.008 Outcomes of Athletes With Genetic Heart Diseases and Implantable Cardioverter-Defibrillators Who Chose to Return to Play DOI: doi.org/10.1016/j.mayocp.2022.03.024
It's rare that a blood donor and a recipient get to connect but that's exactly what happens on this special ENCORE episode of Bloodworks 101 when frequent platelet donor Dan Ertel meets Mack Bell, a 30-year-old African-American man living with cerebral palsy, who contracted a potentially-deadly blood condition called aplastic anemia. That's a deficiency of all types of blood cells caused by failure of bone marrow development.Mack, as you'll discover, was the recipient of several transfusions that played a big role in the effort to save his life. So, here's what happens when someone with a lot to be grateful for gets to thank someone who wasn't expecting it.But there's more. Wait til you hear what's happened since this story first ran in January of 2022.
Commentary by Dr Osung Kwon
Dr Robert-Jan de Vos, sports physician and associate professor at Erasmus Medical Centre in Rotterdam, The Netherlands, dives deep into all things Achilles tendinopathy. In part 2 of this series, Dr de Vos covers the multitude of options for treatment, outside of exercise therapy. Should you and the patient consider corticosteroid injections, PRP injections, heel lifts, shockwave, NSAIDs, or surgery? And when? What are the important clinical considerations when patients choose these options? Part 2 has it all! ------------------------------ RESOURCES Terminating corticosteroid injection in tendinopathy? https://www.jospt.org/doi/10.2519/jospt.2023.11875/ Dutch multidisciplinary guideline on Achilles tendinopathy: (https://pubmed.ncbi.nlm.nih.gov/34187784/ Platelet-rich plasma injection for chronic Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/20068208/ Time to put down the scalpel when treating tendinopathy? https://pubmed.ncbi.nlm.nih.gov/31653777/ Why tendons like load: https://pubmed.ncbi.nlm.nih.gov/29920664/ Clinical diagnosis of Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/34692248/ Clinical tool for identifying spondyloarthropathy: http://tinyurl.com/3my87hma More on the pain monitoring model: https://pubmed.ncbi.nlm.nih.gov/17307888/ Dosing your resistance training in tendinopathy: https://pubmed.ncbi.nlm.nih.gov/37169370/ Best treatment for Achilles tendinopathy (living systematic review): https://pubmed.ncbi.nlm.nih.gov/32522732/
On this episode we speak to Sorina whose passion for foreign languages led her to Japan where she'd meet her husband and give birth to baby Luca. Although she initially hoped to have a natural birth, Hashimoto's disease and her low platelet count deemed her as 'high-risk' which resulted in being induced & then ultimately a C-section.She talks about having to accept her modified birth plans & how alone she felt being 'the only one' she knew of with such health issues.Care facility:+ Nobeoka Hospital------------------------------------------------- Show notes:Miyazaki, Hashimoto's disease, Thrombocytopenia, low platelet count, induced, foley bulbs, oxytocin IV, left occiput anterior (LOA), c-section, jaundice, NICU, anemia, mama guilt, RH negative, Birth Stories of Japan------------------------------------------------- CHAPTERS:00:00 - Opening00:50 - Intro 03:02 - Journey to Pregnancy06:18 - Pregnancy09:39 - Birth Story19:23 - Postpartum recovery25:59 - Costs27:00 - Bottle time32:37 - Outro
Have you ever wondered why some people bruise easily or have bleeding issues? It might be linked to their platelet counts. Today, we explore how nutrient deficiencies can affect your platelets. It is fascinating to learn that something as simple as beef liver or pumpkin seeds could be key to better health. "There are certain foods that are incompatible with your genes, and I think that's really important to take a look at." What you will learn: Platelet Counts and Diet Recommendations Frequency-Specific Microcurrent Treatment Listener Questions on Diet and Health Milk and DNA Diet Considerations To learn more about Dr. Jason West, use the following links: Website Facebook
Chris Paradise, VP of Research and Development at Rion, is taking an acellular approach to developing next-generation regenerative medicines to treat degenerative diseases. The proprietary Rion system PEP, purified exosome product, uses extracellular vesicles or exosomes isolated from human blood platelets to send regenerative messages to cells to stimulate faster healing. This regenerative therapeutic allows for the administration in various forms, such as nebulization for pulmonary conditions and topical application for wounds. Chris explains, "What our focus has shifted towards at Rion is now an acellular approach, so it doesn't involve the use of cells or other components that have been proposed in the past. But we're focusing on extracellular vesicles or exosomes, and we can discuss those in more detail in a minute. But the point of emphasis is that it overcomes many of the limitations the field has previously faced. We're excited to offer reproducible, consistent, and, most importantly, accessible and affordable regenerative therapeutic with a significant impact." "If you think about how two cells communicate with one another, one of the ways they do this is to send messages in little packages between one another, known as extracellular vesicles. It's the fundamental way that cells and tissues more broadly communicate with each other, send signals to one another, and respond to their environment. And so what you find within these vesicles is essentially what one cell is trying to say to another. And they're designed such that they're incredibly stable and designed to do exactly that, which is deliver messages to cells." "I'll back up to the source of the material, which is human platelets. Most people are familiar with platelets as a key component of your blood. If we get an injury or a cut, the bleeding tends to stop relatively quickly. That's because platelets respond to that injury site and form a clot, which stops the bleeding. Much like the conversation about the newfound appreciation for exosomes, I've certainly gained a new appreciation for the impact platelets have, not only on the control of bleeding but, more importantly, the regenerative processes that are jump-started after that to heal the tissues." #RionTX #RegenerativeMedicine #RegenerativeTherapeutics #Acellular #PlateletDerived #Exosomes riontx.com Download the transcript here
Chris Paradise, VP of Research and Development at Rion, is taking an acellular approach to developing next-generation regenerative medicines to treat degenerative diseases. The proprietary Rion system PEP, purified exosome product, uses extracellular vesicles or exosomes isolated from human blood platelets to send regenerative messages to cells to stimulate faster healing. This regenerative therapeutic allows for the administration in various forms, such as nebulization for pulmonary conditions and topical application for wounds. Chris explains, "What our focus has shifted towards at Rion is now an acellular approach, so it doesn't involve the use of cells or other components that have been proposed in the past. But we're focusing on extracellular vesicles or exosomes, and we can discuss those in more detail in a minute. But the point of emphasis is that it overcomes many of the limitations the field has previously faced. We're excited to offer reproducible, consistent, and, most importantly, accessible and affordable regenerative therapeutic with a significant impact." "If you think about how two cells communicate with one another, one of the ways they do this is to send messages in little packages between one another, known as extracellular vesicles. It's the fundamental way that cells and tissues more broadly communicate with each other, send signals to one another, and respond to their environment. And so what you find within these vesicles is essentially what one cell is trying to say to another. And they're designed such that they're incredibly stable and designed to do exactly that, which is deliver messages to cells." "I'll back up to the source of the material, which is human platelets. Most people are familiar with platelets as a key component of your blood. If we get an injury or a cut, the bleeding tends to stop relatively quickly. That's because platelets respond to that injury site and form a clot, which stops the bleeding. Much like the conversation about the newfound appreciation for exosomes, I've certainly gained a new appreciation for the impact platelets have, not only on the control of bleeding but, more importantly, the regenerative processes that are jump-started after that to heal the tissues." #RionTX #RegenerativeMedicine #RegenerativeTherapeutics #Acellular #PlateletDerived #Exosomes riontx.com Listen to the podcast here
Get early access to The Perfect Health Lesson, and the calculator discussed in today's lesson. Click this link now In today's episode: Platelets, also known as thrombocytes, are small cell fragments in the blood that play a crucial role in the body's ability to stop bleeding and form blood clots. When there is an injury or damage to blood vessels, platelets become activated and adhere to the site of injury, where they release various substances to initiate the blood clotting process. This is a normal and essential part of the body's response to injury, preventing excessive bleeding. However, when platelets become overactivated, it can lead to problems, especially in the context of cardiovascular diseases (CVD). Platelet stickiness refers to the tendency of platelets, small blood cells, to adhere to each other or to the walls of blood vessels upon activation. Normally, platelets circulate in the blood in an inactive state. However, when there's injury or damage to blood vessels, platelets become activated, changing shape and releasing chemical signals that prompt them to stick together (aggregate) and adhere to the damaged vessel walls. This adhesive property of platelets is crucial in the process of hemostasis, which is the body's mechanism to prevent excessive bleeding. When blood vessels are injured, platelets adhere to the site of injury, forming a plug to seal the damaged area. This initial platelet aggregation is followed by the coagulation cascade, involving the formation of a blood clot to further stem the bleeding. There are 7 new secrets you will learn about reducing platelet stickiness in this lesson. While platelet stickiness is essential for preventing excessive bleeding, abnormal or excessive platelet aggregation and adhesion can lead to issues like thrombosis, where blood clots form within blood vessels without an injury or obstruction, potentially causing blockages and leading to conditions such as heart attacks or strokes. Therefore, the regulation of platelet stickiness is crucial for maintaining proper hemostasis and preventing abnormal clotting.
For National Blood Donor Month, Courtney Allison speaks with Dr. Elizabeth Stone, assistant director of transfusion medicine at NewYork-Presbyterian and Columbia. Unprecedented blood shortages mean that the need for donated blood is as critical as ever. Dr. Stone demystifies the process of giving blood, explains blood types, and shares how both the recipient and the donor can benefit from a single donation.Click here for the episode transcript.
Dr. Geoffroy Van Innis, DCCJPDr. Van Innis is the first and so far only specialist with a post-doctorate degree in the Upper Neck in all of Europe. His practice is in Ghent, Belgium. He has people traveling from all over Europe to see him. Dr. Van Innis speaks multiple languages. In this episode he talks about his own story and why he decided to make the commitment to travel 27 times in 3 ½ years in order to get the Diplomate of Chiropractic Craniocervical Procedures when he was already a successful chiropractor.Among other topics we discussed:Upper Cervical studies in Europe.What is vitalism?People with Complex issues who are frustrated with the lack of answers.Science vs. philosophy.What is the DCCJP?Collaborating with other specialists.Platelet-rich plasma therapy.Every person is different.The future of chiropractic in Europe.Other podcast episodes related to people and topics discussed in this episode:What can a Diplomate do for you?Dr. Jamie BrowningDr. Jeffery ScholtenTo Contact Dr. Geoffroy Van Innis:https://www.vaninnis.com/:FacebookInstagramTo contact Ruth, go to https://www.blairclinic.comruth@blairclinic.comhttps://www.facebook.com/rutelin
In this week's episode we'll discuss the findings from a phase 2 study of CD24Fc for prevention of graft-versus-host disease, learn more about the origins of chronic active Epstein-Barr virus disease, and discuss the role of PF4 in platelet activation.
In this week's episode we'll discuss the findings from a natural history study of patients with familial platelet disorder with myeloid malignancy, learn more about the role of HEXIM1 as an essential transcription regulator in human erythropoiesis, and discuss the utility of residual disease as a predictor of relapse in CML patients stopping TKI therapy.
On today's podcast we'll discuss high-risk cytogenetic abnormalities in solitary bone plasmacytomas. Then, we'll consider complement activation in vaso-occlusive pain episodes and how targeting C5a generation inhibited those effects. Finally we'll explore the genetics of platelet reactivity and how researchers used this data to develop a genetic score that was associated with risk of thrombotic diseases.
Many people aren't aware there is a therapy available that takes what is already within us and can address the underlying causes of conditions, such as inflammation and immune system imbalances. Our guest today is here to share new research on the regenerative properties of platelets for individuals grappling with persistent symptoms and related co-infections of long-haul COVID, Lyme disease, mold exposure, and more.This is the Story of IV Platelet Therapy with Tapley Holland.EPISODE VIDEO HIGHLIGHTSWatch the Entire EpisodeThe Power of Platelets in TruDOSE Intravenous TreatmentsRebooting the Immune and Repair Systems with TruDOSEUnderstanding the Impact of Cellular Memory in Health RecoveryLyme Disease Patients Find Hope with TruDOSE TherapyThe Impact of TruDOSE on Mycotoxin ExposureCustomizing Health Solutions with TruDOSETruDOSE Therapy: A Transformative Solution for Chronic Health ChallengesInnovative Treatments for Pediatric ConditionsCONNECT WITH TAPLEY HOLLANDWebsite - TruDOSE TherapyListen to Tapley's first ‘Your Health. Your Story.' podcast episode: The Story of TruDose PRP with Tapley Holland CONNECT WITH INNOVATIVE MEDICINE Website Instagram Facebook YouTube CONNECT WITH CASPAR SZULC Instagram Twitter LinkedIn LEARN ABOUT NADOVIM - A BREAKTHROUGH IN BRAIN HEALTHDoctor-formulated, clinically-tested true NAD+ supplement for focus, concentration and cognitive support. Visit our website and save 10% on your first order by using coupon code NADOVIM10. Website Instagram Facebook 'YOUR HEALTH. YOUR STORY.' PODCAST Follow us on Spotify Follow us on iTunes Subscribe on ...
In this week's episode we'll see how targeting the prostacyclin receptor is a promising strategy for regulating hemostasis and thrombosis. Then, we'll learn how new evidence indicates that the progression rate is low in MRD-negative myeloma patients who discontinue post-transplant lenalidomide and dexamethasone maintenance therapy after 2 years. Finally we'll discuss how amphiregulin from leptin receptor-positive niche cells in the bone marrow mediates crosstalk between the niche and hematopoietic stem cells under conditions of DNA repair deficiency and aging.
On this episode, Sonia and Jessica discuss Halloween home decor, baby Halloween costumes, in-home pet cemeteries, the fact that there's a fertility clinic in Greece that is currently reversing menopause for their patients and also recommending a natural approach for those under 50 who prefer to try that as well. The Netflix documentary Unnatural Selection was cancelled- but if we ever get discovered we'll pretend this episode didn't happen; aka feeling cute, might delete later! Topics discussed in this episode: Happy Birthday Dinosaur Sonia, But She's Not Actually 57! (00:21) Annabelle, Hayden and Jess Have Colds (00:52) Our 40th Birthdays (6:04) Loosing Sonia's Kitty Chase (06:55) Jess and Adam's In-Home Pet Cemetery (11:35) Halloween Home Decor & Babies (13:54) Halloween Costumes (17:45) Reversing Menopause Temporarily is Possible, But We're Not Mathers (21:39) Why Did We Want to Be The First Country to Land On The Moon, But Not The First to Jump Start Menopausal Ovaries? (33:31) So You're Saying That We Have to Go to Greece? (38:29) The More Natural Suggestion To Help Women Under 50 Temporarily Reverse Menopause (39:30) The Cancelled Netflix Documentary Unnatural Selection (42:47) Hopefully We Don't Get Cancelled (48:24) The Number of Ultrasounds Covered by Insurance Companies (50:47) The Nuances You'll Find On Our YouTube Videos (55:20) Resources mentioned in this episode: Crete Fertility Centre In Greece Crete Fertility Centre, established 31 years ago, has been offering personalized services to infertile couples, using state-of-the-art technology and psychological support. The result is the birth of over 6000 babies all over the world with the contribution of our unit. Its peaceful location permits the provision of sensitive attention for each couple's individual needs and specific medical circumstances in their quest for parenthood. The international level, state of the art facilities, ensure that the highest quality of care is available. Medical and laboratory equipment are the most modern currently available, while standards of hygiene, health and safety are exemplary, in full compliance with the highest and strictest levels in Europe. These have already been confirmed by ISO Certification procedure, having the respective specification by the 24th of February of 2010. Moreover, since November 8th 2017, it is one of the few clinics in Europe that has the DIN EN 15224 certification, which is the European framework for standards for the development and implementation of healthcare management systems. It is noteworthy that Crete Fertility Centre is located on the seafront in one of the biggest and & most beautiful islands in the Mediterranean, Crete. Thus, it is not surprising that couples travelling to this familiar holiday destination find that the tranquil setting on this beautiful island, lessens the inevitable anxiety and tension of imminent fertility treatment. Add to this, our cost effective pricing policy (compared to other European and countries worldwide) and the highest standards of medical expertise, science and health, establishes Crete Fertility Centre as the best choice for cost, effectiveness and safety for all ART needs. 12 Things to Know About Emerging Therapies for Menopause Reversal Greek fertility physicians invented the procedure known as ovarian rejuvenation for menopause reversal. Platelet-rich plasma is injected into your ovaries during the surgery (PRP). PRP is a concentrated solution made from your own blood and is employed in different areas of medicine. The process is based on the PRP's inherent growth factors, which can help with: Regeneration of tissue, increased blood flow, and decreased inflammation The theory is that it may also reverse signs of aging in your ovaries and activate previously dormant eggs. Doctors tested this in a small research with eight women in their 40s. Each of these women had gone around five months without a period. To assess how well their ovaries were working, researchers measured their hormone levels at the start of the study and every month after that. All of the participants resumed their regular periods after one to three months. The mature eggs were then accessible to the doctors for fertilization. Getting pregnant after beginning perimenopause is doable: Although difficult, being pregnant during perimenopause is not impossible. Your ovaries might start releasing eggs again after a surgery like ovarian rejuvenation. Your ovaries' mature follicles rupture during ovulation to release an egg or eggs. Ovulation becomes less regular after perimenopause sets in, and you don't release a viable egg every month. The fact that your ovaries still contain healthy eggs is what matters. The ovarian rejuvenation technique might aid in restoring or rebalancing the hormones that regulate follicle maturation and bursting. This will enable you to conceive naturally or will enable medical professionals to retrieve an egg for In-Vitro-Fertilization(IVF). Researchers discovered that all four participants produced an egg that could be harvested for fertilization in the one peer-reviewed study that had been done up to that point. Ovarian Rejuvenation How ovarian rejuvenation works: Stem Cells can, under the proper biological stimulus, morph into any type of cell in the human body, including eggs. The presence of Stem Cells in the ovaries and their transformation into mature oocytes (egg cells) has been demonstrated in mice by Harvard researchers. Stem Cells have also been shown to be present in the human ovary, so it is quite possible that they can be transformed into eggs by Growth Factors contained in the individuals' own white blood cells and platelets which have been injected into the ovary. Injections of Growth Factors, when used for many other types of medical treatments, are made from a patient's own blood and blood cells. The Latest results at the Crete Clinic: According to our latest data, the success rates of PRP reach over 85% and according to our data so far, the pregnancy rates that we have achieved after PRP are 48%, of which 26% was achieved with natural conception. Both PRP techniques, transvaginal ultrasound and laparoscopy, can be carried out in our clinic. The success rates of both techniques coincide. Our experience in the field of fertility has been evident by the study that we have done and it has already been published with data from 2017 – 2018 and it is the most extensive study in the world as far as the number of the patients are concerned. In a short while, our new study with a sample of about 500 patients will be published which will prove our new data which is even more encouraging and exceptional. Enriched PRP Platelet Rich Plasma (PRP) is an innovative regenerative therapy, which involves the application of autologous platelet-leukocyte-rich plasma containing growth factors and thrombin directly to the site of treatment. PRP treatment has been used broadly in several areas of medicine and aesthetics to relieve pain, reduce inflammation, initiate healing and of course regeneration and rejuvenation of the tissues. The degranulation of platelets releases the biological factors into the site giving the beneficial effect. To increase the efficiency of the PRP, Crete Fertility Centre started to apply a novel technology by enriching and fortifying that with growth factors (Enriched PRP – EnPRP), derived from the patient's own blood. The most important benefit of the Enriched PRP – EnPRP is that it contains over 10 times higher concentration of growth factors and cytokines. Evidence from research shows that it is the growth factors that reside in the platelet granules that are responsible for inducing healing and regeneration. With this novel technique we managed to break the billions of platelets and directly get the growth factors and cytokines. So, we offer an extra energy to the ovarian rejuvenation process, by applying them directly. This way, we fortify and make more efficient the PRP effect on the ovarian stem cells. This treatment acts on the ovary, reversing the aging process of the follicles and awakening their development process. It is at least 10 times more effective and efficient from the PRP alone and it has direct and long-lasting effect. Similar is the effect of the Enriched PRP – EnPRP to the uterine and vaginal rejuvenation. Regarding the uterine Enriched PRP – EnPRP, our first results revealed that it has greater efficacy on the endometrial growth and subsequently on the pregnancy rates, since pregnancy rate is increased with growing endometrial thickness. EnPRP makes the endometrium (lining) friendly for the embryos during an IVF or spontaneous pregnancy. Melatonin & Menopause Reversal For Women Under 50 Researchers have been looking at the relationships between melatonin and menopause for a long time. Your pineal gland produces the hormone that promotes sleep aka melatonin. According to earlier studies, the pineal gland starts to decrease as menopause approaches. Melatonin is thought by scientists to be crucial in the synthesis of reproductive hormones. The levels of reproductive hormones start to fall off without it. According to one study, women between the ages of 43 and 49 who received a nightly dose of 3 milligrams of melatonin had their periods return. These participants were either menopausal or in the perimenopausal stage. Ages 50 to 62 participants showed no impacts. Melatonin may be a natural, risk-free method of postponing, or perhaps possibly reversing, menopause, though more research is needed in this area. 3mg Melatonin About this item Rest Support - Melatonin is a hormone that is released from the pineal gland, a pea-sized endocrine gland located in the brain. One of melatonin's principal functions is to help regulate rest by controlling our day and night biological rhythms, known as the 'circadian rhythm' or our 24-hour biological clock. Melatonin- 3 mg of quality melatonin in each capsule. * Important Antioxidant - Melatonin also supports healthy immune and stress responses and is an important antioxidant, which acts as an effective scavenger of free radicals. * Always Pure & Effective Products - This product is Non-GMO and contains No Gluten, Dairy, or Soy.* Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients. Thank you for listening! For questions and comments about this episode, please contact us here! (Scroll to the bottom of the page).
Platelets -- the part of blood that helps control bleeding -- are lifesaving for cancer patients, those receiving organ or bone marrow transplants, victims of trauma, and patients undergoing open-heart surgery. But donated platelets have a shelf-life of only 5-7 days. What if we could extend the life of platelets? What if modern platelet use is based on outdated assumptions? Dr. Moritz Stolla of Bloodworks Research institute wants to find out.
In this week's episode, we discuss the findings from a phase 2 study of lenalinomide plus rituximab in elderly frail patients with DLBCL, learn more about platelet GP6-mediated neutrophil recruitment in early stages of acute lung injury, and discuss a newly identified isoform of the tyrosine kinase AXL, termed AXL3, in mantle cell lymphoma.
Today we're talking all about women's sexual health: Everything from the complexities of the human body to the science behind orgasms, vaginal health, and libido. It's astonishing to know that conditions such as urinary incontinence (which affects between 10 to 20 million women), is the primary reason women are placed in nursing homes. Additionally, around 50 million women suffer from some form of sexual dysfunction. Platelet-rich fibrin (PRF) provides a safe, natural method for vaginal rejuvenation. PRF is autologous, meaning it is biocompatible; derived from your own blood. This reduces the risk of allergic reactions or rejections. With the growth factor release of PRF, we can stimulate regeneration and enhance collagen, which improves vaginal tightness, structure, and tone. Women's sexual health has been neglected in terms of research funding. Myths still surround hormone therapy and the potential hazards of Premarin. It's crucial to bust these myths and bring to light how a positive sexual experience can create a healthy feedback loop for arousal. Additionally, bioidentical hormones can rejuvenate a woman's libido, providing a more enjoyable sexual experience. Remember, women's sexual health is a significant part of overall wellbeing. There is a glaring disparity in research and treatment options, but advancements are creating ripples in the field. The journey towards better understanding of women's sexual health is ongoing, and we all need to be part of it. Join us as we continue exploring the transformative advancements in women's health. Don't let societal norms or lack of information hold you back. It's time to open our minds and invest in our sexual health, and by extension, our overall wellbeing. Sign up for RepeatMD www.beautyculturespa.com @beautyculture.medspa
In this episode, we review the high-yield topic of Uremic Platelet Dysfunction from the Heme section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets
This week's episode will be focusing on inherited platelet disorders We will go over the important details on the roles of platelets, platelet parts as well as the diagnosis of inherited platelet disorders through aggregation studies as well as the treatment of these disorders.
View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Mohit Khera is a world-renowned urologist with expertise in sexual medicine and testosterone therapy. In this episode, Mohit provides a comprehensive overview of male sexual health. He begins with an in-depth exploration of erectile dysfunction, shedding light on its prevalence across different age groups, diagnostic methods, and its intriguing connection to cardiovascular disease. He then ventures into Peyronie's disease, penile fractures, penile enlargement treatments, prolonged erections, premature ejaculation, and anorgasmia. Shifting gears, Mohit delves into the intricate workings of testosterone, DHT, and estrogen, emphasizing their physiological significance and interplay. He explains blood tests for diagnosing low testosterone, the correlation between symptoms and blood levels in cases of low testosterone, and the pros and cons of different methodologies for increasing testosterone. He concludes with a thought-provoking conversation about the role of testosterone in patients with prostate cancer and addresses concerns surrounding DHT, finasteride, and post-finasteride syndrome. We discuss: Mohit's career path and interest in sexual medicine and infertility [3:00]; The anatomy of the male genitalia [5:45]; The prevalence of sexual dysfunction, its impact on quality of life, and the importance of seeking help [7:15]; Erectile dysfunction (ED): definition, diagnosis, pathophysiology, and more [11:00]; The history of medications to treat ED and the mechanisms of how they work [15:30]; Relationship between aging and erectile dysfunction and Mohit's approach to treating patients and prescribing medications [20:00]; The impact of lifestyle on sexual health and the association between ED and cardiovascular disease [29:30]; Causes and treatments for Peyronie's Disease, penile fracture, and more [37:30]; The value of ultrasound for ED diagnosis and management strategies [47:45]; Various treatment options for ED: injections, penile prosthesis, and more [50:15]; Priapism (prolonged erection): what is happening and when to seek treatment [57:15]; Shockwave therapy as a treatment for ED [1:02:45]; Stem cell therapy for ED [1:08:15]; Platelet-rich plasma (PRP) injections as a treatment for ED [1:12:00]; Premature ejaculation (PE): prevalence, pathophysiology, and treatment [1:14:45]; Anorgasmia: causes and treatment [1:22:00]; The interplay of sex hormones, the impact of aging, symptoms of low testosterone, and considerations for testosterone replacement therapy (TRT) [1:26:45]; Methods for increasing endogenous testosterone [1:38:45]; Testosterone replacement therapy: various forms of exogenous testosterone, weighing risk vs. reward, and more [1:52:30]; The physiology and purpose of testosterone and DHT, why some men feel fine even with “low” testosterone, personalized approaches to treating low testosterone, and more [2:02:30]; Post-finasteride syndrome [2:09:00]; The role of testosterone in prostate cancer and addressing the notion that TRT could increase risk [2:16:15]; The effects of testosterone as an adjunct to therapy for estrogen-sensitive breast cancer in women [2:27:15]; Resources for those looking for healthcare providers [2:28:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube
While studying to become a nutritionist and raising her children, today's guest Shanais Pelka faced a respiratory infection that led to a platelet disorder. Traditional treatments didn't work, so she took her health into her own hands. Through extensive research and experimentation, she discovered the power of herbs and supplements in improving her health and healed herself. Today she is an herbalist, nutritionist, health educator, and a dedicated mother of three with a passion for food, herbs, medicinal mushrooms, sustainability, and community. After running her own nutrition bar company and spending time in Costa Rica, Shanais found a new calling at Organifi. She now leads their Research & Development efforts, bringing her expertise to the forefront of the health and wellness industry. Today she's sharing her healing journey with us and how we can use superfoods and adaptogens to enhance our health. Thank You to Our Sponsors, Organifi! Organifi, is a line of organic superfood blends that offers plant based nutrition made with high quality ingredients. Organifi takes pride in offering the best tasting superfood products on the market at a price that works out to less than $3 a day. Get the Sunrise to Sunset Kit, and Enjoy a FREE 30-Day Sample of Pure The Sunrise to Sunset Kit helps transform your entire day in 3 simple steps: a detoxifying morning reset, an afternoon energy boost, and a nighttime relaxation tea, all packed with superfoods your body will love. This kit comes with built-in bundle savings, and for a limited-time, it also includes a 30-day supply of our brain-boosting blend, Pure, absolutely free! The Sunrise to Sunset Kit Includes: Green Juice Reset your body every morning with 11 detoxifying superfoods – including ashwagandha, an adaptogen researched for cortisol regulation in the body. You'll love the delicious taste, and your body will love the rush of exotic micronutrients. Promotes balanced cortisol and stress levels Perfect for weight management Helps detox the body of harmful toxins Red Juice A caffeine-free energy boost provided by nature's best: 5 antioxidant-rich berries plus 4 powerful adaptogens (including cordyceps and Rhodiola) to promote natural and sustained stamina and endurance. Natural energy boost without caffeine High in antioxidants Low sugar, sweet berry taste Gold Ease your body into a calm, relaxed state with 9 soothing superfoods and adaptogens like Reishi mushroom, turmeric, and ginger, all in a delicious nighttime tea. Get the restful sleep you deserve. Incredible taste and aroma Promotes recovery while you rest Naturally calming with zero negative side effects Pure (Included For a Limited Time!) Clear your mind with this brain-boosting blend. Pure is made with natural compounds that help repair, protect, and feed your brain cells while addressing the gut-brain axis. Support improved digestion, focus, and clarity! Stimulates BDNF in the brain Promotes stimulation in learning and memory Supports strong cognitive function Go to www.organifi.com/foodheals and use code foodheals for 20% off, plus free shipping and FREE 30-Day Sample of Pure! Learn more about your ad choices. Visit megaphone.fm/adchoices