Podcasts about Platelet

Today, I'm joined by the pioneering duo behind Young Goose and two of the earliest voices to bring longevity science into the world of skincare. Amitay comes from the red light therapy space, while Anastasia's background is rooted in cancer research and regenerative medicine—together, their bold thesis is that youthful skin is not just about appearance, it's an energy state.   Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer.   Episode Timestamps: Skin longevity: appearance vs resilience vs long-term health ... 00:06:42 Why topical NAD matters for skin ... 00:14:07 Importance and decline of NAD as we age ... 00:18:26 Why spermidine was added to skincare ... 00:21:00 How spermidine drives autophagy and hydration ... 00:25:43 Spermidine's impact on wrinkles and skin barrier ... 00:29:06 Longevity skincare vs traditional approaches ... 00:31:18 Methylene blue's unique benefits and formulation ... 00:34:04 Methylene blue vs other antioxidants ... 00:36:16 Methylene blue's role in recovery and protection ... 00:46:13 Platelet-derived, quantified exosomes explained ... 00:51:44 How to layer exosomes in your skincare ... 01:01:13 Biggest myths in skin longevity ... 01:02:41 Does topical NAD and spermidine really work? ... 01:08:28 Where to start with Young Goose products ... 01:19:33   Our Amazing Sponsors: Digestive Bitters by Just Thrive - One capsule before eating helps your body absorb more nutrients, ease digestion, and leave you feeling light instead of weighed down. Head over to Justthrivehealth.com/discount/NAT and use code NAT20 for 20% off. Puori: It's minimally processed, made from pasture-raised cows' milk, and it's tested for over 200 contaminants every single batch. It's also very Yummy! Go to Puori.com/NAT and use code NAT for 20% off— it also applies to subscriptions so you'll get nearly a third off the price. Thymus & Pineal BioRegulators by Natures Marvels - Thymus Bioregulator helps keep immune response balanced and small human studies in older adults link it with healthier immune markers and fewer seasonal respiratory issues. Pineal Bioregulator supports your natural melatonin/circadian rhythm so you get the kind of sleep that underpins immune resilience. Head to profound-health.com and use code LONGEVITY15 for 15% off your first order.   Nat's Links:  YouTube Channel Join My Membership Community Sign up for My Newsletter  Instagram  Facebook Group

This week on Health Matters, we revisit Courtney Allison's conversation with Dr. Elizabeth Stone, assistant director of transfusion medicine at NewYork-Presbyterian and Columbia. Unprecedented blood shortages mean that the need for donated blood is as critical as ever. Dr. Stone demystifies the process of giving blood, explains blood types, and shares how both the recipient and the donor can benefit from a single donation.___Dr. Elizabeth Stone is Assistant Director of Transfusion Medicine and Cellular Therapy at NYP Columbia University, Medical Director of Clinical Pathology at NYP Westchester Hospital, and Assistant Professor of Pathology and Cell Biology at Columbia University Irving Medical Center. Dr. Stone's research focuses on platelet storage conditions and platelet utilization. With advances in medical care, the demand for platelets continues to increase. She is particularly interested in investigating how platelet storage conditions may affect transfusion in different clinical scenarios and in platelet alloimmunization, with the ultimate goal to improve clinical outcomes for patients requiring platelet transfusions. ___Health Matters is your weekly dose of health and wellness information, from the leading experts. Join host Courtney Allison to get news you can use in your own life. New episodes drop each Wednesday.If you are looking for practical health tips and trustworthy information from world-class doctors and medical experts you will enjoy listening to Health Matters. Health Matters was created to share stories of science, care, and wellness that are happening every day at NewYork-Presbyterian, one of the nation's most comprehensive, integrated academic healthcare systems. In keeping with NewYork-Presbyterian's long legacy of medical breakthroughs and innovation, Health Matters features the latest news, insights, and health tips from our trusted experts; inspiring first-hand accounts from patients and caregivers; and updates on the latest research and innovations in patient care, all in collaboration with our renowned medical schools, Columbia and Weill Cornell Medicine.To learn more visit: https://healthmatters.nyp.org Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Got a story idea for Bloodworks 101? Send us a text message Ohio's Al Whitney is 88 years old and in the blood banking industry, he's become a bit of a legend. Why? Well, as Bloodworks 101 producer John Yeager found out, that's because Al Whitney is a man on a mission to save lives.  

Editor's Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from September 13-19, 2025.

Send us a textA certain portion of pilots develop low platelet counts, otherwise known as thrombocytopenia.  On this episode, we look at how platelets work in the body, what happens if there are not enough platelets, and why the FAA even cares.  Having a good plan in place with your AME to deal with this condition is important when considering aeromedical certification.

Got a story idea for Bloodworks 101? Send us a text message At Bloodworks, we like to say that platelets are "golden." Why? well, as producer John Yeager tells us in the special ENCORE EDITION of Bloodworks 101, it's because they have such an impact on the people who receive them. But it's also because of the time and sacrifice it takes to produce them. For this edition, John spoke to Bloodworks' Senior Product Strategy Manager Kyle Boynton. 

Quinn comes to you LIVE to read fan mail, discuss casual dining franchises, and put his foot down regarding Oktoberfest rules

In this episode of Fill Me In, Jon and Nicole dive into the latest hot topic in aesthetics: Platelet Derived Growth Factor (PDGF). They discuss the effectiveness of PDGF in enhancing various treatments, from microneedling to under-eye and hair restoration injections. They explain their techniques for administering PDGF, the benefits compared to PRP, and the importance of reconstitution with bacteriostatic saline. With insights from their experiences and emerging protocols, they shed light on the potential of PDGF to revolutionize the aesthetics industry. Moxie helps medspa entrepreneurs reach multimillion dollar growth—with marketing, compliance, coaching, software, and VIP pricing, all in one place.Fill Me In listeners get $500 off their Moxie launch fee! Sign-up for your free 30-minute medspastrategy session and walk away with your personalized retention and rebooking game plan!Just click here: joinmoxie.com/fillmein***DISCLAIMER***The content of this episode of Fill Me In: An Aesthetics Podcast is intended for educational and informational purposes only and does not constitute medical advice. While PDGF (Platelet-Derived Growth Factor) is FDA-approved for certain topical applications, it is not approved by the FDA for injectable use. Any discussion of injectable PDGF reflects off-label use, which carries potential risks and should only be considered under the guidance of a licensed and qualified medical professional.The hosts, guests, and producers of this podcast do not endorse or recommend the off-label use of any medical product without proper clinical training, patient assessment, and full informed consent. Listeners are strongly advised to consult with their healthcare providers and adhere to all applicable laws and regulatory guidelines. We expressly disclaim any and all liability for any outcomes related to the use or misuse of the information presented in this episode.PDGF Resources:Lynch Regenerative Medicine: https://www.lynchregen.com/Waseem Garbia PA-C | https://www.instagram.com/unfilteredinjector/ | https://www.patreon.com/user?u=79797191Erika Barry NP-C | https://www.instagram.com/injectorbunny/ | patreon.com/Botoxbunny1Olivia Salmen FNP-BC CPSN | https://www.instagram.com/oliviasalmen_aesthetics/ On Fill Me In: An Aesthetics Podcast, Jon LeSuer NP-C and Nicole Bauer FNP-BC dive deep in the world of aesthetics. As aesthetic nurse practitioners with their own medical practices, Jon and Nicole fill you in on everything in their field.Fill Me In is hosted by Jonathan LeSuer, MSN, NP-C, and Nicole Bauer, MSN, APRN, FNP-BC. Follow Fill Me In on Instagram!https://www.instagram.com/thefillmeinpod/Follow Nicole on Instagram:https://www.instagram.com/aestheticnursenicole/Follow Jon on Instagram:https://www.instagram.com/injectorjon/Exhibit Medical Aesthetics website:https://exhibitmedicalaesthetics.com/Tox and Pout Aesthetics website:https://toxandpout.com/Producer of Fill Me In: Joseph Ginexi

In this week's episode, we'll learn about a JAK inhibitor to prevent complications of CD19-directed CAR T-cell therapy. In a phase 2 study, itacitinib was well tolerated and demonstrated promising reductions in the incidence of cytokine release syndrome and neurotoxicity. After that: investigators report direct interactions between ChAdOx1 and platelets under arterial shear conditions. Investigators say it's a novel biophysical mechanism that potentially contributes to post-vaccination arterial thrombosis. Finally, we explore lineage switch, an emerging form of acute leukemia relapse with dismal outcomes. It arises rapidly following antigen-targeted immunotherapy, highlighting the importance of advanced methods for detection and treatment.Featured Articles: Itacitinib for the prevention of IEC therapy–associated CRS: results from the 2-part phase 2 INCB 39110-211 studyShear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosisProject EVOLVE: an international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia

This week our intrepid primary care docs discuss 4 new POEMs: spironolactone vs amiloride for resistant hypertension, mirtazapine for insomnia in older adults, baloxivir for influenza post exposure prophylaxis, and platelet-rich plasma injections for knee osteoarthritis. We've got opinions!Show notes:Spironolactone vs amiloride for resistant hypertension: pubmed.ncbi.nlm.nih.gov/40366680/ Mirtazapine for chronic insomnia: https://pubmed.ncbi.nlm.nih.gov/40135470/ Baloxavir to prevent flu in household contacts: https://pubmed.ncbi.nlm.nih.gov/40267424/ Platelet-rich plasma for knee OA: https://pubmed.ncbi.nlm.nih.gov/39751394/

What do you do when your joints hurt? Do you think this is only temporary because I did too much of something? What can you do when joints hurt, or at least ache? Are you thinking or told about knee replacement? If this is you, this is your episode!   My Guest:  Dr. Joshua Schacter, DO, FAAOS, America's Holistic Orthopedic Surgeon, is redefining joint care with a commitment to providing actual solutions for his patients. Spending a decade as the Chief of Orthopedic Surgery and Director of the Advanced Orthopedic Center of Excellence, he saw the need for non-invasive, innovative solutions that address the root causes of pain and dysfunction rather than masking symptoms. When his wife was diagnosed with the “breast cancer gene”, the Schacter's became obsessed with wellness, health and how to accomplish true healing. Dr. Schacter dreamed of a more effective and patient-centered approach, the Pinnacle Method.   Questions We Answer in This Episode: [00:05:25] How did your personal experience cause you to shift your focus from traditional orthopedic care to a more holistic and integrative approach?  [00:21:18] What is orthobiologics?  [00:20:20] How does The Pinnacle Method address not just the symptoms but the root causes of joint pain? How does the Pinnacle Method help patients achieve long-term wellness? [00:21:30] How do the treatments you offer support the natural healing process? [00:37:00] Can you define PRP? The efficacy and timeline, cost and success rate?  [00:37:35] What do you find to be true today on surgery and non-surgical treatments? What evidence or success stories would you share to illustrate the effectiveness of the Pinnacle Method? [00:39:30] Your approach is optimizing overall health and longevity. How do you incorporate wellness and prevention into your care for patients?   Know What You Can Do When Joints Hurt   What is orthobiologics? Use of the body's own healing capacity. Includes PRP (platelet-rich plasma), stem cells from fat or bone marrow, cord blood.   What is PRP? Platelet-rich plasma: Draw blood → concentrate platelets → inject into affected joint Cost: $2,000–$6,000 per dose   What is The Pinnacle Method? Combines PRP, functional medicine, and BHRT Addresses the whole patient, not just symptoms   Key Takeaways Orthobiologics like PRP and stem cells are effective alternatives to surgery, especially when used early. Steroid injections can accelerate joint degeneration and should be used cautiously. The Pinnacle Method is a patient-centered approach combining regenerative orthopedics, functional medicine, and hormone therapy. Menopause-related hormonal changes significantly affect joint health, making hormone balance crucial. Connect with Dr. Joshua: Website - Pinnacle Sports Medicine Facebook - Dr. Joshua Schachter Instagram - @drjoshuaschacter Instagram - @pinnacleintegrativeorthopedics YouTube - @drknighthawk   Other Episodes You Might Like: Previous Episode - Extended Cardio and Low Protein Equal Short Term Weight Loss Next Episode - 5 Reasons You're Not Losing Weight or Gaining Muscle After 50 More Like This - Do You Have a Dominant Side? Joint Pain Solutions I'm Using Right Now More Like This - A Trek Up Mt Kilimanjaro with 3 Artificial Joints at 70   Resources: Join the Flipping50 Membership for evidence-based workout programs. Short & Easy Exercise videos in this 5 Day Flip Challenge.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend! I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Jess: What are some alternatives to Daily Nutrition Support to get my vitamins and protein when I am sensitive to Stevia/Monk fruit/artificial sugars? Would your daily multivitamin, in pill form, in addition to a bone broth protein be efficient?                                                                                                                                                                                           Jenny: Hi Dr. Cabral - I'd love to get your thoughts on all the "fillers" I see so many women (young adult to mature adult) getting these done on lips. I see ads stating the hyaluronic acid is "healthy for the deeper layers of the skin and lips", but I'm skeptical and concerned for friends and family who get them with some frequency. I have no interest in getting them, but would love to know the real truth in the event they are open to an objective opinion about them. And I don't know what Botox really is, but I'm interested in your thoughts on that, also. I always cringe when I see people who have had both - they just don't look so natural any more. Thank you!                                                                                                                            Jodie: Can you use Dijon mustard on the 7 day detox?                                                                                                                             Julia: I have a 2 year old who is now being diagnosed with reactive airways (multiple inhalers, saying it's asthma with no cure), and a 10 month old who has recently this month had multiple breath holding spells that are terrifying as a parent to have a child experience as you hold them in your arms. Our family seems to benefit from a low histamine diet after I had a trigger cleaning mold from an object in our new home and 5 years all living with a home with a wall of black mold in the basement. What probiotics of supplements can help young, young kids (10 months, 2, and daughter is 4) to become healthy from reactive airways, breath holding spells, histamine intolerance? We have AirOasis purifiers now in bedrooms. Also, wildfire air quality starting to he a problem here in Midwest- advice? Thx                                                                Judy: Is there any protocol or supplements that can help with low blood platelets count? My 86 year old in-law has liver cancer and low platelets count. Also he has water retention all over his legs, even though he is taking water pills to remove the water. Any help is greatly appreciated!       Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right! - - - Show Notes and Resources: StephenCabral.com/3446 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

In this episode of Speaking of Mol Bio, Dr. Beth Webb takes us deep into the world of platelets, often misunderstood components of blood that punch far above their weight in both physiological and pathological processes. As a postdoctoral researcher at the University of Leeds, Dr. Webb explores how endothelial signals influence platelet activity, and how these anucleate cell fragments play roles not only in clotting, but also in immune responses, inflammation, and diseases like cardiovascular disorders and COVID-19.Beth unpacks the technical challenges of isolating and analyzing platelets—particularly in RNA sequencing and qPCR—while stressing the importance of sample purity and the presence of platelet subpopulations. The conversation also touches on the hope of personalized medicine through platelet-based diagnostics and tailored antiplatelet therapies.Beyond the lab, Dr. Webb is an active science communicator, sharing tips on engaging broader audiences through social media, blogs, and video. She emphasizes the importance of resilience, creativity, and starting small when communicating science. Whether you're a cell biologist, a hematology enthusiast, or a fellow communicator, this episode offers something for everyone. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

This episode discusses the use of Platelet Factor 4, which has several roles for applicability, limitations, and emerging areas for use. CE for this episode expires two years after its original publication date. The information presented during the podcast reflects solely the opinions of the presenter. The information and materials are not, and are not intended as, a comprehensive source of drug information on this topic. The contents of the podcast have not been reviewed by ASHP, and should neither be interpreted as the official policies of ASHP, nor an endorsement of any product(s), nor should they be considered as a substitute for the professional judgment of the pharmacist or physician.

Today we do a round-up of some of the recent semaglutide trials. Does semaglutide ever miss? But what about tirzepatide, which causes even more weight loss?We also review two new critical care trials, FLUID and the UK-ROX, new platelet transfusion guidelines, and a new retrospective study of apixaban vs rivaroxaban vs warfarin. Oral Semaglutide for Diabetes with Cardiovascular Disease or CKD (SOUL)Semaglutide for Peripheral Artery Disease (STRIDE)Semaglutide for MASH (ESSENCE)Semaglutide vs Tirzepatide for Obesity (SURMOUNT-5)Normal Saline vs Lactated Ringers (FLUID)Conservative Oxygen Targets in Mechanically Ventilated Patients (UK-ROX)Platelet Transfusion GuidelinesApixaban vs Rivaroxaban vs Warfarin Music from Uppbeat (free for Creators!): https://uppbeat.io/t/soundroll/dope License code: NP8HLP5WKGKXFW2R

Editor's Summary by Linda Brubaker, MD, and Preeti Malani, MD, MSJ, Deputy Editors of JAMA, the Journal of the American Medical Association, for articles published from May 24-30, 2025.

A central question in platelet transfusion is whether to follow a restrictive or liberal strategy in decisions about which patients should receive platelets. Author Ryan Metcalf, MD, University of Utah, discusses new clinical guidelines for platelet transfusion and more with JAMA Executive Editor Gregory Curfman, MD. Related Content: Platelet Transfusion Red Blood Cell Transfusion in the Intensive Care Unit Small-Volume Blood Collection Tubes to Reduce Transfusions in Intensive Care Red Blood Cell Transfusion Trends in Red Blood Cell, Plasma, and Platelet Transfusions in the United States, 1993-2014

John Norman is a normal dude who made a blood platelet donation one day. When his colleague told him that donated platelets helped save her life, John decided to keep rolling with the donations. He donates every other week, which is now over 160 times! Support the show: https://www.normalfolks.us/premiumSee omnystudio.com/listener for privacy information.

John Norman is a normal dude who made a blood platelet donation one day. When his colleague told him that donated platelets helped save her life, John decided to keep rolling with the donations. He donates every other week, which is now over 160 times! Support the show: https://www.normalfolks.us/premiumSee omnystudio.com/listener for privacy information.

Got a story idea for Bloodworks 101? Send us a text message At Bloodworks, we like to say that platelets are "golden." Why? well, as Bloodworks 101 producer John Yeager found out, it's because they have such an impact on the people who receive them. But it's also because of the time and sacrifice it takes to produce them. For this edition, John spoke to Bloodworks' Senior Product Strategy Manager Kyle Boynton. 

TWiV reviews passing of Ann Palmenberg, deadly illness in western Congo, US disruption of mpox and ebolavirus programs, first measles death in Texas outbreak, flu vaccine selection meeting postponed, US withdraws from polio, malaria, HIV programs and more, clade 2.3.4.4b H5N1 viruses have a long HA stalk, and systems vaccinology to identify predictors of durable antibody response to multiple vaccines in humans. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support science education at MicrobeTV ASV 2025 Ann Palmenberg dies (Cress) Ann at Chumakov Symposium (YouTube) Unknown illness in Congo (NY Times) Bad news about mpox outbreak (NPR) US interrupts Ebola prevention program (NPR) First measles death in Texas (Texas Trib) Flu vaccine selection meeting canceled (NY Times) US ends funding for polio, HIV, malaria and more (NY Times) Clade 2.3.4.4b H5N1 neuraminidase has a long stalk (mBio) Predictors of durable antibody responses to vaccines (Nat Immunol) Review of adjuvants (Vaccinol Methods Vacc Res) Timestamps by Jolene Ramsey. Thanks! Weekly Picks Brianne – Video of the Northern Lights from Space Rich – Vaccination for Sudan Ebola virus disease Alan – Specialized moth wing scales give it 3-D camouflage (news and paper) Vincent – WHO Recommendations for Influenza Vaccine Composition for the 2025-2026 Northern Hemisphere Influenza Season Listener Picks Gerry – Eukaryotic Transcription Anne – The science of the solar system Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

CME credits: 1.00 Valid until: 31-01-2026 Claim your CME credit at https://reachmd.com/programs/cme/fetalneonatal-alloimmune-thrombocytopenia-fnait-the-platelet-equivalent-of-rh-disease/32275/ Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can lead to substantial medical challenges for the mother, fetus, and neonate. Diagnosis is often difficult without low platelet counts or frank bleeding. But a mother's risk for FNAIT can be assessed, and existing and newly emerging therapies can act as preventive measures and improve fetus/neonate outcomes. Join Drs. Karin Blakemore and Emilie Vander Haar as they address many of the issues surrounding the management of FNAIT and offer clear and actionable suggestions for you to bring into your clinical practice.

In this episode, Dr. Joseph Purita, Medical Director at PUR-FORM & Regenerative Medicine Pioneer, discusses the intricate relationship between inflammation and aging, emphasizing the importance of lifestyle choices, dietary habits, and supplements in promoting longevity. He explains the concept of immunosenescence and how it contributes to chronic inflammation, which is a significant factor in many diseases. He and Dr. Anthony Balduzzi also cover the role of regenerative medicine in treating conditions like arthritis and the potential of various supplements to enhance health and well-being. Dr. Purita explains various regenerative medicine techniques, including PRP, stem cells, peptides, and gaseous therapies like hyperbaric oxygen and ozone. He emphasizes the importance of light therapy in enhancing healing and the role of peptides in recovery. The discussion also touches on the future of personalized medicine, highlighting the potential impact of AI and the need for a healthier culture.Key TakeawaysInflammation is a key factor in aging and disease.Immunosenescence refers to aging immune cells that contribute to inflammation.A healthy lifestyle, including exercise and diet, is crucial for longevity.Intermittent fasting can be an effective strategy for health.Olive oil and a Mediterranean diet are beneficial for reducing inflammation.Urolithin A enhances mitochondrial health and function.Regenerative medicine can improve joint health but cannot reverse aging.Exercise is the most effective medicine for overall health.Dietary choices significantly impact inflammation and health outcomes.Supplements can support health but should complement a healthy lifestyle. Prolotherapy creates local inflammation to enhance healing.Platelet-rich plasma (PRP) releases growth factors essential for healing.Stem cells are part of a larger symphony of regenerative cells.Photobiomodulation uses light therapy to benefit cellular health.Peptides like BPC 157 and TB 500 can enhance healing processes.Hyperbaric oxygen therapy increases oxygen delivery to tissues.Ozone therapy can help reduce inflammation and viral load.Hydrogen therapy acts as a potent antioxidant and anti-inflammatory.AI will play a significant role in the future of personalized medicine.The goal is to increase health span, not just lifespan.Where to learn more about PUR-FORMWebsite: https://purformhealth.com/Instagram: https://www.instagram.com/purformhealth/Facebook: https://www.facebook.com/purformhealth/TikTok: https://www.tiktok.com/@purformhealthBiographical Information on Dr. Joseph PuritaDr. Joseph Purita is a pioneering expert in Regenerative Cell and PRP therapy for orthopedic conditions. After graduating from Georgetown University Medical School, he completed his surgical internship at the University of Florida Medical Center. He then completed his orthopedic surgery residency at the University of Miami-Jackson Memorial Hospital, where he served as the Chief Administrative Resident.Since joining the Boca Raton Orthopedic Group (BROG) in 1981, Dr. Purita has established himself as a leader in the field of orthopedic surgery and regenerative medicine. He currently serves as Chief Medical Officer at PUR-FORM in Boca Raton. A globally recognized authority, Dr. Purita trains...

In this episode, Dr. Joseph Purita, Medical Director at PUR-FORM & Regenerative Medicine Pioneer, discusses the intricate relationship between inflammation and aging, emphasizing the importance of lifestyle choices, dietary habits, and supplements in promoting longevity. He explains the concept of immunosenescence and how it contributes to chronic inflammation, which is a significant factor in many diseases. He and Dr. Anthony Balduzzi also cover the role of regenerative medicine in treating conditions like arthritis and the potential of various supplements to enhance health and well-being. Dr. Purita explains various regenerative medicine techniques, including PRP, stem cells, peptides, and gaseous therapies like hyperbaric oxygen and ozone. He emphasizes the importance of light therapy in enhancing healing and the role of peptides in recovery. The discussion also touches on the future of personalized medicine, highlighting the potential impact of AI and the need for a healthier culture.Key TakeawaysInflammation is a key factor in aging and disease.Immunosenescence refers to aging immune cells that contribute to inflammation.A healthy lifestyle, including exercise and diet, is crucial for longevity.Intermittent fasting can be an effective strategy for health.Olive oil and a Mediterranean diet are beneficial for reducing inflammation.Urolithin A enhances mitochondrial health and function.Regenerative medicine can improve joint health but cannot reverse aging.Exercise is the most effective medicine for overall health.Dietary choices significantly impact inflammation and health outcomes.Supplements can support health but should complement a healthy lifestyle. Prolotherapy creates local inflammation to enhance healing.Platelet-rich plasma (PRP) releases growth factors essential for healing.Stem cells are part of a larger symphony of regenerative cells.Photobiomodulation uses light therapy to benefit cellular health.Peptides like BPC 157 and TB 500 can enhance healing processes.Hyperbaric oxygen therapy increases oxygen delivery to tissues.Ozone therapy can help reduce inflammation and viral load.Hydrogen therapy acts as a potent antioxidant and anti-inflammatory.AI will play a significant role in the future of personalized medicine.The goal is to increase health span, not just lifespan.Where to learn more about PUR-FORMWebsite: https://purformhealth.com/Instagram: https://www.instagram.com/purformhealth/Facebook: https://www.facebook.com/purformhealth/TikTok: https://www.tiktok.com/@purformhealthBiographical Information on Dr. Joseph PuritaDr. Joseph Purita is a pioneering expert in Regenerative Cell and PRP therapy for orthopedic conditions. After graduating from Georgetown University Medical School, he completed his surgical internship at the University of Florida Medical Center. He then completed his orthopedic surgery residency at the University of Miami-Jackson Memorial Hospital, where he served as the Chief Administrative Resident.Since joining the Boca Raton Orthopedic Group (BROG) in 1981, Dr. Purita has established himself as a leader in the field of orthopedic surgery and regenerative medicine. He currently serves as Chief Medical Officer at PUR-FORM in Boca Raton. A globally recognized authority, Dr. Purita trains surgeons in...

The use of assistive devices when treating unruptured aneurysms is widespread in neurointerventional practice. But there is no standard for how long patients should receive dual anti-platelet therapy after the procedure, to protect them from thrombotic complications. Durations can range from one month to one year. This episode looks at a review of patient data across 12 locations to understand the effect of therapy duration on risk of complications.  Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Andrew Ringer¹, first author of the paper:  Impact of duration of dual anti-platelet therapy on risk of complications after stent-assisted coiling of unruptured aneurysms 1. Mayfield Clinic, Cincinnati, Ohio, USA Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Dr Robert-Jan de Vos, sports physician and associate professor at Erasmus Medical Centre in Rotterdam, The Netherlands, dives deep into all things Achilles tendinopathy. In part 2 of this series, Dr de Vos covers the multitude of options for treatment, outside of exercise therapy. Should you and the patient consider corticosteroid injections, PRP injections, heel lifts, shockwave, NSAIDs, or surgery? And when? What are the important clinical considerations when patients choose these options? Part 2 has it all! ------------------------------ RESOURCES Terminating corticosteroid injection in tendinopathy? https://www.jospt.org/doi/10.2519/jospt.2023.11875/ Dutch multidisciplinary guideline on Achilles tendinopathy: (https://pubmed.ncbi.nlm.nih.gov/34187784/ Platelet-rich plasma injection for chronic Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/20068208/ Time to put down the scalpel when treating tendinopathy? https://pubmed.ncbi.nlm.nih.gov/31653777/ Why tendons like load: https://pubmed.ncbi.nlm.nih.gov/29920664/ Clinical diagnosis of Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/34692248/ Clinical tool for identifying spondyloarthropathy: http://tinyurl.com/3my87hma More on the pain monitoring model: https://pubmed.ncbi.nlm.nih.gov/17307888/ Dosing your resistance training in tendinopathy: https://pubmed.ncbi.nlm.nih.gov/37169370/ Best treatment for Achilles tendinopathy (living systematic review): https://pubmed.ncbi.nlm.nih.gov/32522732/ Achilles Pain, Stiffness, and Muscle Power Deficits - 2024 updated clinical practice guideline: https://www.jospt.org/doi/10.2519/jospt.2024.0302

In this week's episode, unravelling follicular lymphoma subtypes. Researchers dissect the biological diversity of follicular lymphoma and introduce a new prognostic mode, that could change the way this B-cell neoplasm is subtyped and treated. Then, concerning stroke rate trends in sickle cell disease. A new report shows increasing rates of cerebrovascular events among people with SCD in California. Finally, procoagulant platelet activation promotes venous thrombosis. Investigators report finding procoagulant platelets in the circulation and in thrombi of patients and mice with DVT or PE. Featured Articles:Follicular lymphoma comprises germinal center–like and memory-like molecular subtypes with prognostic significanceRates of strokes in Californians with sickle cell disease in the post-STOP eraProcoagulant platelet activation promotes venous thrombosis

Top Sports Medicine Articles Podcast – PRP vs. Steroid Injections for Tennis Elbow Dr. Moira Davenport discusses the #8 article of 2023, “Corticosteroid Injections for the Treatment of Lateral Epicondylitis are Superior to Platelet-rich Plasma at 1 Month but Platelet-rich Plasma is More Effective at 6 Months: An Updated Systematic Review and Meta-analysis of Level 1 and 2 Studies,” which was originally published in The Journal of Shoulder and Elbow Surgery in September 2023. Dr. Jeremy Schroeder serves as the series host. Dr. Davenport is a member of the AMSSM Top Articles Subcommittee, and this episode is part of an ongoing mini journal club series highlighting each of the Top Articles in Sports Medicine from 2023, as selected for the 2024 AMSSM Annual Meeting. Corticosteroid Injections for the Treatment of Lateral Epicondylitis are Superior to Platelet-rich Plasma at 1 Month but Platelet-rich Plasma is More Effective at 6 Months: An Updated Systematic Review and Meta-analysis of Level 1 and 2 Studies https://www.jshoulderelbow.org/article/S1058-2746(23)00395-6/abstract

Hannah's facebook status from sixteen years ago today was this ... "Hannah is enjoying being home after the annoying day of another platelet transfusion."Hannah rarely complained, so this expression of annoyance revealed a lot about how she felt about platelet transfusions.  She had battled platelet issues off and on throughout the early months of her treatment, and once again, low platelets were becoming an ongoing problem.Thank you for joining me for another bonus episode of the While We're Waiting podcast in this year-long series in which I share our family's experiences as our teenage daughter Hannah battled glioblastoma brain cancer from February 2008 through February 2009.  My desire is to process through the events of those twelve months with the perspective that 16 years has brought … and point listeners to hope in Jesus along the way.I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

In this week's episode, we'll learn about the role of a platelet-specific glycoprotein receptor in abdominal aortic aneurysm formation, the influence of TP53 mutations on outcomes for patients with 5q-deleted myelodysplastic syndrome, and a rational combination treatment intended to produce more durable responses in patients with refractory B-cell acute lymphoblastic leukemia who are treated with CAR T-cell therapy.Featured Articles:Soluble glycoprotein VI predicts abdominal aortic aneurysm growth rate and is a novel therapeutic targetInfluence of TP53 gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletionA phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia

In this episode of “Answers From the Lab,” host Bobbi Pritt, M.D., chair of the Division of Clinical Microbiology at Mayo Clinic, is joined by Dong Chen, M.D., Ph.D., chair of the Division of Hematopathology in the Department of Laboratory Medicine and Pathology at Mayo Clinic. They discuss rare and inherited platelet disorders and esoteric laboratory testing of hematologic disorders.Specific topics of discussion include:How these rare disorders are diagnosed through laboratory tests.Why platelet transmission electron microscopy is considered the gold standard for diagnosing disorders like Hermansky Pudlak syndrome, Wiskott-Aldrich syndrome, Chediak Higashi syndrome, and Jacobson/Paris-Trousseau syndrome.The process involved with developing and validating the PTEM test (Mayo ID: PTEM) at Mayo Clinic.The importance of ongoing research and advocacy to enhance care for patients with rare platelet disorders.

Send us a textIn this episode, we discuss the epidemiology, clinical manifestations, investigations and treatment of ITP. Our medicine minute discusses the Harrington-Hollingsworth Experiment. Written by: Dr. Vanessa Giuliano (Internal Medicine Resident)Reviewed by: Drs. Taylor Dear and Zachary Liederman (Hematology) and Dr. Kevin Venus (General Internal Medicine)Infographic by: Dr. Lilly Yu (Internal Medicine Resident)Support the show

In this episode, Dr. Rohrich is joined by Dr. Sam Lynch to discuss what's new in PDGF.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter In this “Ask Me Anything” (AMA) episode, Peter dives deep into the topic of hair loss, exploring its relationship with aging and its impact on quality of life. The conversation focuses on androgenic alopecia, the most common form of hair loss in both men and women, and covers the differences in patterns and causes between the sexes. Peter delves into the right timing for treatment, breaking down various options such as minoxidil and finasteride, low-level laser therapy, platelet-rich plasma injections, and more. Additionally, Peter outlines the pros and cons of the two primary hair transplantation methods and concludes with practical advice on selecting the right specialist or treatment team for those facing hair loss. If you're not a subscriber and are listening on a podcast player, you'll only be able to hear a preview of the AMA. If you're a subscriber, you can now listen to this full episode on your private RSS feed or our website at the AMA #63 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here. We discuss: The impact of hair loss on emotional health [2:15]; The prevalence, patterns, and causes of hair loss in men and women [5:15]; The genetic and hormonal causes of hair loss, and the role of dihydrotestosterone (DHT) in androgenic alopecia [8:45]; The visual differences in hair loss patterns between men and women, and the importance of consulting a specialist to rule out non-genetic causes of hair loss [13:30]; How genetic predisposition influences the risk of androgenic alopecia, and how early detection through diagnostic tools and blood tests can help manage risk more effectively [16:45]; Ideal timing for starting treatment: why early treatment is crucial for effectively managing hair loss [19:30]; The various FDA-approved treatments for androgenic alopecia, their mechanisms, and additional off-label treatments commonly used to manage hair loss [24:30]; Topical minoxidil—the most commonly recommended starting treatment for hair loss [30:15]; Oral vs. topical minoxidil: efficacy, ease of use, and potential side effects that must be considered [33:45]; Finasteride for treating hair loss: efficacy, potential side effects on libido, and the need for careful PSA monitoring in men to avoid missing early signs of prostate cancer [37:15]; Other effective hair loss treatments for women: boosting hair density with spironolactone gel and ketoconazole shampoo as part of a comprehensive strategy [41:30]; Low-level laser therapy: effectiveness, costs, practicality, and a comparison of in-office treatments with at-home devices [49:00]; Platelet-rich plasma (PRP) as a treatment for hair loss: potential effectiveness, varying protocols, and significant costs [53:45]; Hair transplant for advanced hair loss: criteria and considerations [58:00]; Types of hair transplants: follicular unit transplantation (FUT) vs. follicular unit extraction (FUE) [1:02:00]; The financial cost of hair transplant surgery, and what to consider when seeking affordable options [1:06:15]; The potential risks and downsides of the various hair transplant procedures [1:09:30]; Post-procedure care for hair transplants and whether the procedure must be repeated periodically [1:16:30]; Combining different hair loss treatments: benefits, risks, and considerations [1:18:30]; Emerging hair loss treatments with limited data [1:21:00]; Key considerations for selecting the right treatment plan for hair loss [1:22:00]; A summary of the different considerations for men and women facing hair loss [1:24:30]; Practical advice on selecting the right specialist or treatment team [1:26:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

In this week's episode we'll discuss the mutational and transcriptional landscape of pediatric BCP lymphoblastic leukemia; learn more about the role of platelet-derived TGF-β1 in immune thrombocytopenia; and discuss the findings from a phase 3 trial of mavorixafor in WHIM syndrome.Featured Articles:Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma Platelet-derived TGF-β1 induces functional reprogramming of myeloid-derived suppressor cells in immune thrombocytopenia Phase 3 randomized trial of mavorixafor, CXCR4 antagonist, in WHIM syndrome 

If I had known how important platelets were going to become in the life of our family, I probably would have paid closer attention in my junior high science class!  Sixteen years ago today, Hannah's bloodwork showed a continued downward trend in her platelet levels, leading to the postponement of her next chemotherapy treatment.  While Hannah was happy about that, we were anxious to get back on track with her therapy.  Today's bonus espiode describes the mixed emotions of that time.  Thank you for joining me for another bonus episode of the While We're Waiting podcast in this year-long series in which I share our family's experiences as our teenage daughter Hannah battled glioblastoma brain cancer from February 2008 through February 2009.  My desire is to process through the events of those twelve months with the perspective that 16 years has brought … and point listeners to hope in Jesus along the way.I would love to hear your thoughts on the show. Click here to send me a message!All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

Today, we explore a groundbreaking research paper published in JCI Insight by Ma and colleagues in June 2020, titled “Platelet factor 4 is a biomarker for lymphatic-promoted disorders.” The study, which included contributions from Dr. Stanley Rockson at Stanford University and Dr. Guillermo Oliver at Northwestern, aimed to identify a biomarker for lymphatic dysfunction and improve the diagnosis of lipedema, further confirming that lipedema is a lymphatic disorder.

Growth Factors, Exosomes, Biohacking - Join us in this week's podcast where we sit down with Dr. Samuel Lynch, an accomplished scientist, inventor, and CEO of Ariessence! Dr. Lynch introduces us to his groundbreaking product, Ariessence Pure PDGF+, a platelet-derived growth factor used in aesthetic applications. He shares his journey from a decade of lab research to pioneering biotech innovations and discusses the rigorous process of developing FDA-approved products. We delve into the unique benefits of recombinant DNA technology, talking about how Ariessence accelerates wound healing, reduces downtime post-procedures, and enhances skin health by promoting collagen and blood supply. Dr. Lynch also explains how Ariessence can work faster than PRP due to its higher concentration, making it a great alternative to use after a microneedling treatment. We touch on the differences between growth factors and exosomes, biohacking trends, and where we see the future of regenerative medicine heading. Tune in to learn about the revolutionary potential of Ariessence in the field of aesthetics!

Are you experiencing bedroom blues and struggling to rise to the occasion? Erectile dysfunction (ED) can be a frustrating issue for men. If you're affected by ED, there may be a new treatment option you haven't heard of yet. Platelet-rich plasma (PRP) therapy uses your own blood, your platelets, to potentially improve your erectile function. In this episode, I will explain what PRP therapy is and how it works. I'll also discuss the possible benefits of this treatment. Listen now to find out if it could be right for you!--------------If you liked this episode, please SUBSCRIBE, like, leave a comment, and share so we can keep bringing you valuable content that gets results!--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://sexualhealthformenpodcast.com/platelets-restore-erectile-function--------------Ready to empower your health journey? Secure your FREE PDF copy of the “5 Natural Solutions to Overcome ED” today! Dive into knowledge that could transform your life. Click the link below to claim your copy

Welcome to Ask Stago, The Podcast dedicated to provide expert answers to your expert questions in coagulation. In today's episode, Karine Carrière  will explain further what are microvesicles, their importance in coagulation and how to analyze them.  Literature sources: [Tesselaar et al.], [Lacroix et al.] [Faille et al.] [Mullier et al.] Vallier et al.] . [Nieuwland et al.] Kim HK, Song KS, Park YS, Kang YH, Lw YJ, Lw KR, et al. Elevated levels of circulating platelet microparticles, VEGF, 11-6 and FiANTES in patients Wlth gastrlc cancer. possible mle of a metastasis predlotor. Eur J Cancer 2003;39(2):184-91. Helley D, Banu E, Bouziane A, Banu A, Scotte F, Fiher AM, et al. Platelet microparticles: a potential predictive factor of survival in hormone-reac pmstate cancer patients treated with docetaxel-based chemotherapy. Eur Urnl2009;56(3):479-84. Zwicker JI, Liebman HA, Neuberg D, Lecmix R, Bauer KA, Furie BC, et ai. Tmr-derived tissue factor-bearing microparticles are associated with venous thromboembolic events in malignancy. Clin Cancer Res 2009; 15 (22): 68630-40   Content is scientific and technical in nature. It is intended as an educational tool for laboratory professionals and topics discussed are not intended as recommendations or as commentary on appropriate clinical practice.

Zach, Emily, Mo & Mayes Would you bargain hunt for a medical procedure? Or is that one area where you want to pay for quality? Zach had a shouting match this morning over literal dog poop. Hacks had an EXCELLENT season finale and is a contender for show of the year. We break down temperature like a Katy Perry song. Would you rather be Hot or Cold? The dos and donts of meeting your significant other's parents. Patreon Exclusive: Are corn dogs and beef wellingtons basically the same thing? COUNT THE DINGS MERCH STORE - Check it out here: https://bit.ly/CTDMERCH Sign up for Underdog Fantasy Promo Code DING: https://play.underdogfantasy.com/p-count-the-dings If you want to hear the full Mailbag, check out the Patreon! Join the Count The Dings Patreon for exclusive full, ad free episodes, extra Cinephobe content and more at www.patreon.com/CountTheDings Watch the Mailbag on YouTube: https://www.youtube.com/@CountTheDings Learn more about your ad choices. Visit megaphone.fm/adchoices

Platelet-rich plasma (PRP) therapy is making headlines in the field of fertility, with ovarian PRP emerging as a promising approach for women facing certain egg quality challenges. This type of treatment involves injecting a woman's own platelet-rich plasma into her ovaries. PRP is a concentration of platelets and growth factors created from a patient's own blood. These growth factors can stimulate cellular regeneration and may help to improve ovarian function and increase IVF success.  Its been used for decades in the beauty industry, hair growth and in healing a variety of conditions. Why not try it for fertility as well?!  Dr. Jesse Hade, MD, REI and his colleagues at Generation Next Fertility Center in NYC conducted a study to assess just that. They found that this therapy may be particularly beneficial for women experiencing premature ovarian failure or diminished ovarian reserve, conditions that impact the quantity and quality of eggs available for fertilization. Ovarian PRP is also being explored as a treatment option for women who have had poor responses to IVF cycles.Tune in as we are joined by Dr. Jesse Hade, MD, REI - a compassionate board-certified reproductive endocrinologist with over two decades of private practice experience, is a leading expert in fertility and has earned numerous awards for his research. Is Ovarian PRP right for you? Listen in and find out! You'll Learn: What Ovarian PRP treatment is How PRP treatment is beneficial for fertility Who can benefit from this treatment Thanks so much for listening to our podcast! If you enjoyed this episode and think others would love to hear it, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode or want to be a guest on the show? Leave a comment in the section below or visit the website to contact me!www.naturnalife.comSubscribing to The Podcast:If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast on Apple Podcasts, Stitcher, Spotify, Amazon, or whatever your favorite podcast app is!Ratings and reviews from our listeners are extremely valuable to us and greatly appreciated. They help our podcast rank higher on Apple Podcasts, which exposes our show to more awesome listeners like you. So if you have a minute, please leave a review on Apple Podcasts! 

By April 19, 2008, Hannah had been undergoing radiation treatments five days a week and taking an oral chemotherapy drug daily since mid-March. The intensity of these ongoing treatments was finally beginning to take a toll, as you will hear from the email update I sent on this date sixteen years ago ...Thank you for joining me for another bonus episode of the While We're Waiting podcast in this year-long series in which I share our family's experiences as our teenage daughter Hannah battled glioblastoma brain cancer from February 2008 through February 2009.  My desire is to process through the events of those twelve months with the perspective that 16 years has brought … and point people to hope in Jesus along the way.All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

Dr. Scott Paradise continues the countdown and reviews articles No. 5 and No. 4 of 2022 on this episode of the Top Sports Medicine Articles podcast, which is hosted by Dr. Jeremy Schroeder. The first article is the #5 article, “Platelet-rich Plasma Injection vs. Operative Treatment for Lateral Elbow Tendinosis: A Systematic Review and Meta-analysis,” which was originally published in the Journal of Shoulder and Elbow Surgery in February 2022. The second article was selected as the #4 of 2022, examining the “Outcomes of Athletes With Genetic Heart Diseases and Implantable Cardioverter-Defibrillators Who Chose to Return to Play,” which was originally published in the Mayo Clinic Proceedings in November 2022. Dr. Paradise is a member of the AMSSM Top Articles Subcommittee, and this episode is part of an ongoing mini journal club series highlighting each of the Top Articles in Sports Medicine from 2022, as selected for the 2023 AMSSM Annual Meeting in Phoenix, AZ. Platelet-rich Plasma Injection vs. Operative Treatment for Lateral Elbow Tendinosis: A Systematic Review and Meta-analysis DOI: doi.org/10.1016/j.jse.2021.09.008 Outcomes of Athletes With Genetic Heart Diseases and Implantable Cardioverter-Defibrillators Who Chose to Return to Play DOI: doi.org/10.1016/j.mayocp.2022.03.024

It's rare that a blood donor and a recipient get to connect but that's exactly what happens on this special ENCORE episode of Bloodworks 101 when frequent platelet donor Dan Ertel meets Mack Bell, a 30-year-old African-American man living with cerebral palsy, who contracted a potentially-deadly blood condition called aplastic anemia. That's a deficiency of all types of blood cells caused by failure of bone marrow development.Mack, as you'll discover,  was the recipient of several transfusions that played a big role in the effort to save his life. So, here's what happens when someone with a lot to be grateful for gets to thank someone who wasn't expecting it.But there's more. Wait til you hear what's happened since this story first ran in January of 2022. 

Dr Robert-Jan de Vos, sports physician and associate professor at Erasmus Medical Centre in Rotterdam, The Netherlands, dives deep into all things Achilles tendinopathy. In part 2 of this series, Dr de Vos covers the multitude of options for treatment, outside of exercise therapy. Should you and the patient consider corticosteroid injections, PRP injections, heel lifts, shockwave, NSAIDs, or surgery? And when? What are the important clinical considerations when patients choose these options? Part 2 has it all! ------------------------------ RESOURCES Terminating corticosteroid injection in tendinopathy? https://www.jospt.org/doi/10.2519/jospt.2023.11875/ Dutch multidisciplinary guideline on Achilles tendinopathy: (https://pubmed.ncbi.nlm.nih.gov/34187784/ Platelet-rich plasma injection for chronic Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/20068208/ Time to put down the scalpel when treating tendinopathy? https://pubmed.ncbi.nlm.nih.gov/31653777/ Why tendons like load: https://pubmed.ncbi.nlm.nih.gov/29920664/ Clinical diagnosis of Achilles tendinopathy: https://pubmed.ncbi.nlm.nih.gov/34692248/ Clinical tool for identifying spondyloarthropathy: http://tinyurl.com/3my87hma More on the pain monitoring model: https://pubmed.ncbi.nlm.nih.gov/17307888/ Dosing your resistance training in tendinopathy: https://pubmed.ncbi.nlm.nih.gov/37169370/ Best treatment for Achilles tendinopathy (living systematic review): https://pubmed.ncbi.nlm.nih.gov/32522732/

For National Blood Donor Month, Courtney Allison speaks with Dr. Elizabeth Stone, assistant director of transfusion medicine at NewYork-Presbyterian and Columbia. Unprecedented blood shortages mean that the need for donated blood is as critical as ever. Dr. Stone demystifies the process of giving blood, explains blood types, and shares how both the recipient and the donor can benefit from a single donation.Click here for the episode transcript.

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Mohit Khera is a world-renowned urologist with expertise in sexual medicine and testosterone therapy. In this episode, Mohit provides a comprehensive overview of male sexual health. He begins with an in-depth exploration of erectile dysfunction, shedding light on its prevalence across different age groups, diagnostic methods, and its intriguing connection to cardiovascular disease. He then ventures into Peyronie's disease, penile fractures, penile enlargement treatments, prolonged erections, premature ejaculation, and anorgasmia. Shifting gears, Mohit delves into the intricate workings of testosterone, DHT, and estrogen, emphasizing their physiological significance and interplay. He explains blood tests for diagnosing low testosterone, the correlation between symptoms and blood levels in cases of low testosterone, and the pros and cons of different methodologies for increasing testosterone. He concludes with a thought-provoking conversation about the role of testosterone in patients with prostate cancer and addresses concerns surrounding DHT, finasteride, and post-finasteride syndrome. We discuss: Mohit's career path and interest in sexual medicine and infertility [3:00]; The anatomy of the male genitalia [5:45]; The prevalence of sexual dysfunction, its impact on quality of life, and the importance of seeking help [7:15]; Erectile dysfunction (ED): definition, diagnosis, pathophysiology, and more [11:00]; The history of medications to treat ED and the mechanisms of how they work [15:30]; Relationship between aging and erectile dysfunction and Mohit's approach to treating patients and prescribing medications [20:00]; The impact of lifestyle on sexual health and the association between ED and cardiovascular disease [29:30]; Causes and treatments for Peyronie's Disease, penile fracture, and more [37:30]; The value of ultrasound for ED diagnosis and management strategies [47:45]; Various treatment options for ED: injections, penile prosthesis, and more [50:15]; Priapism (prolonged erection): what is happening and when to seek treatment [57:15]; Shockwave therapy as a treatment for ED [1:02:45]; Stem cell therapy for ED [1:08:15]; Platelet-rich plasma (PRP) injections as a treatment for ED [1:12:00]; Premature ejaculation (PE): prevalence, pathophysiology, and treatment [1:14:45]; Anorgasmia: causes and treatment [1:22:00]; The interplay of sex hormones, the impact of aging, symptoms of low testosterone, and considerations for testosterone replacement therapy (TRT) [1:26:45]; Methods for increasing endogenous testosterone [1:38:45]; Testosterone replacement therapy: various forms of exogenous testosterone, weighing risk vs. reward, and more [1:52:30]; The physiology and purpose of testosterone and DHT, why some men feel fine even with “low” testosterone, personalized approaches to treating low testosterone, and more [2:02:30]; Post-finasteride syndrome [2:09:00]; The role of testosterone in prostate cancer and addressing the notion that TRT could increase risk [2:16:15]; The effects of testosterone as an adjunct to therapy for estrogen-sensitive breast cancer in women [2:27:15]; Resources for those looking for healthcare providers [2:28:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

While studying to become a nutritionist and raising her children, today's guest Shanais Pelka faced a respiratory infection that led to a platelet disorder. Traditional treatments didn't work, so she took her health into her own hands. Through extensive research and experimentation, she discovered the power of herbs and supplements in improving her health and healed herself. Today she is an herbalist, nutritionist, health educator, and a dedicated mother of three with a passion for food, herbs, medicinal mushrooms, sustainability, and community. After running her own nutrition bar company and spending time in Costa Rica, Shanais found a new calling at Organifi. She now leads their Research & Development efforts, bringing her expertise to the forefront of the health and wellness industry. Today she's sharing her healing journey with us and how we can use superfoods and adaptogens to enhance our health. Thank You to Our Sponsors, Organifi! Organifi, is a line of organic superfood blends that offers plant based nutrition made with high quality ingredients. Organifi takes pride in offering the best tasting superfood products on the market at a price that works out to less than $3 a day. Get the Sunrise to Sunset Kit, and Enjoy a FREE 30-Day Sample of Pure The Sunrise to Sunset Kit helps transform your entire day in 3 simple steps: a detoxifying morning reset, an afternoon energy boost, and a nighttime relaxation tea, all packed with superfoods your body will love. This kit comes with built-in bundle savings, and for a limited-time, it also includes a 30-day supply of our brain-boosting blend, Pure, absolutely free! The Sunrise to Sunset Kit Includes: Green Juice Reset your body every morning with 11 detoxifying superfoods – including ashwagandha, an adaptogen researched for cortisol regulation in the body. You'll love the delicious taste, and your body will love the rush of exotic micronutrients. Promotes balanced cortisol and stress levels Perfect for weight management Helps detox the body of harmful toxins Red Juice A caffeine-free energy boost provided by nature's best: 5 antioxidant-rich berries plus 4 powerful adaptogens (including cordyceps and Rhodiola) to promote natural and sustained stamina and endurance. Natural energy boost without caffeine High in antioxidants Low sugar, sweet berry taste Gold Ease your body into a calm, relaxed state with 9 soothing superfoods and adaptogens like Reishi mushroom, turmeric, and ginger, all in a delicious nighttime tea. Get the restful sleep you deserve. Incredible taste and aroma Promotes recovery while you rest Naturally calming with zero negative side effects Pure (Included For a Limited Time!) Clear your mind with this brain-boosting blend. Pure is made with natural compounds that help repair, protect, and feed your brain cells while addressing the gut-brain axis. Support improved digestion, focus, and clarity! Stimulates BDNF in the brain Promotes stimulation in learning and memory Supports strong cognitive function Go to www.organifi.com/foodheals and use code foodheals for 20% off, plus free shipping and FREE 30-Day Sample of Pure! Learn more about your ad choices. Visit megaphone.fm/adchoices