Podcasts about qol

Clash Bashing joins to discuss everything in the June Update. Support the man by using code BASH in the shops.Links:Clash Bashing on YouTubeCompetitive Clash Network Discord (For Esports Everything)We're part of Supercell's Creators Program; find more information here: https://creators.supercell.com/en/supercell-partner Timestamps:(00:00) Intro and Happy Father's Day(02:10) Crafting Station(25:30) Ice Block DE Spell(31:51) New Levels(40:39) Cookbook(48:44) QoL, Bug Fixes, and Misc(56:44) Listener Questions

Jagex just dropped a MASSIVE blog full of amazing QOL updates that we are very excited for! Dont have time to read through it? Thats fine, we got you covered. Sit back and enjoy as we go through this blog and give you our thoughts. Community Question: If you could change the drop table of any boss in the game, to either make it totally busted....or more balanced, how would it change?

It's episode 295! That means...nothing! BUT, GGG had a great interview with Talkative Tri this week and we gleaned a bunch of information for both the future of Path of Exile 1 and PoE 2! With our private league coming to a close and GGG teasers, we hope you had a great Path of Exile week! Thank you, as always, for your listens each and every week. We love your faces!(00:00:00) Welcome to Forever Exiled and episode intro(00:00:27) Shoutout to our patrons(00:01:23) How was your week?(00:05:11) Neck issues and manual labour(00:09:30) Sleeping, stretching, and healing(00:11:30) Path of Exile begins(00:19:07) Getting crafts in PoE 2(00:24:15) POE1 burnout and switching to PoE 2(00:28:40) Storytelling in PoE 2 vs PoE 1(00:34:18) Big changes in the next PoE 2 patch(00:40:02) Passive tree and character building(00:46:10) PoE 2 lab discussion(00:51:00) Auto tree points and lab QoL(00:56:28) PoE 1 stash tabs and UI suggestions(01:00:43) Final thoughts and wrap upForever Exiled Info:www.foreverexiled.comPatreonTwitter @ForeverExiled82Path of Exile WebsiteWrecker of Days Builds ListDiscord...FE Merch StoreFE Nexus Store

Dr Raquel Faria and Professor David Isenberg discuss the impact of neurological events in SLE including their associated mortality risk, effect on patients' QoL, fatigue and persistent neurological impairment throughout life.Disclaimer: During Lupus Academy podcast episodes, participants may refer to off-label use of medicines for patients with lupus. Lupus Academy does not make anyrecommendations about using a medicine outside the terms of its approved license for use.

It's In the News.. a look at the top headlines and stories in the diabetes community. This week's top stories: Tandem's new infusion set is approved, Dexcom G7 compatibility with the Omnipod 5 iPhone app announced, Sernova cell-pouch moves forward, GLP-1 meds for T1D, and more! Find out more about Moms' Night Out  Please visit our Sponsors & Partners - they help make the show possible! Learn more about Gvoke Glucagon Gvoke HypoPen® (glucagon injection): Glucagon Injection For Very Low Blood Sugar (gvokeglucagon.com) Omnipod - Simplify Life Learn about Dexcom   Check out VIVI Cap to protect your insulin from extreme temperatures The best way to keep up with Stacey and the show is by signing up for our weekly newsletter: Sign up for our newsletter here Here's where to find us: Facebook (Group) Facebook (Page) Instagram Twitter Check out Stacey's books! Learn more about everything at our home page www.diabetes-connections.com  Reach out with questions or comments: info@diabetes-connections.com Episode transcription with links: Hello and welcome to Diabetes Connections In the News! I'm Stacey Simms and every other Friday I bring you a short episode with the top diabetes stories and headlines happening now. XX Tandem gets FDA clearance for a new infusion set. The company shared in an SEC filing that its Capillary Biomedical (CapBio) subsidiary won clearance for its SteadiSet Infusion Set. SteadiSet features an integrated inserter with a hidden needle designed for one-handed insertion. It received clearance to deliver insulin for up to three days of use. However, Tandem plans to submit a separate request to extend the indicated use time to up to seven days. It doesn't expect to begin commercial activities for SteadiSet until after it receives clearance for the extended use time. Many of us have been following this since Tandem acquired CapBio back in 2022.. it's been pretty hush hush – CapBio has never accepted my requests for interviews, so I'm excited to see this approval, mostly because my son really really needs it! https://www.drugdeliverybusiness.com/tandem-capbio-fda-clearance-insulin-infusion-set/ XX   Insulet just announced via an email to health care providers that Dexcom G7 compatibility with the Omnipod 5 iPhone app will be released IN THE COMING WEEKS! Great news for people with #t1d and XX Sernova announces positive interim data from its ongoing Phase 1/2 clinical trial in patients with T1D. this is their Cell Pouch Bio-hybrid Organ as a functional cure for type 1 diabetes (T1D), today Interim data from 12 patients with transplanted human donor islet cells show patients achieving insulin independence, islet cell engraftment in Cell Pouch, islet function, islet survival, improved glycemic control, improved patient reported quality of life (QOL) and improved awareness of hypoglycemia and increased sensitivity to severe hypoglycemic symptoms. Improvement in patient outcomes was correlated with a cumulative increase in the quantity of transplanted islets. Based on these findings, the study is on track to meet its primary and secondary endpoints, and the confirmatory Cohort C is expected to initiate in H2 2025.   Clinical trials with iPSC islet-like clusters from Sernova's partner, Evotec, are anticipated to begin in 2026 after completion of Cohort C of the ongoing trial. These interim findings, with 8 of 12 patients achieving insulin independence so far, support the thesis that Sernova's high volume ten channel Cell Pouch, used in Cohort B, plus an optimised immune suppression regimen, has the potential to achieve insulin independence, without portal vein transplant, in our planned clinical trial with Evotec's high quality iPSC islet-like clusters. Measured HbA1c (a blood test that shows the average blood sugar levels over the past 2-3 months) in patients with Cell Pouch alone, showed that 9 of 12 patients had a reduced value within the American Diabetes Association (ADA) recommended range of

Praises or critics can be send here! Also if there's anything you wish to hear about please send your requests here!Contradictory player opinions about Classic and Retail WoW reveal fundamental disconnects between what players claim they want and what they actually enjoy.• Classic players simultaneously demand "no changes" while requesting quality-of-life improvements• Season of Discovery controversy highlights player confusion—it maintains Classic gameplay while adding QoL features• Class balance in Classic is objectively poor with fury warriors dominating, yet purists resist improvements• Perfect balance is impossible in MMOs while maintaining meaningful class identity• Returning Retail players complain about complexity without specific examples• Modern WoW's questing is actually more streamlined than ever with clear guidance• Gear and crafting systems in Retail are straightforward when explained properly• The WoW community often makes sweeping generalizations without nuanced understanding of game designCheck out all my socials down below and visit my Etsy shop for WoW-related merchandise!Hope you all enjoy and hope you relate to any of these stories. And I will speak to you all in the next episode!Want some 3D printed Merch, find it here!https://pigandwhistletales.etsy.comSupport the show here:https://www.buzzsprout.com/1196870/supportpatreon.com/Pigandwhistlehttps://www.buymeacoffee.com/PigandWhistleSocials :Twitch : https://www.twitch.tv/pigandwhistletalesYoutube : https://www.youtube.com/channel/UCAOi6rHO3x90lOmmb82Jv1wWebsite : https://www.pigandwhistletales.com/Instagram : https://www.instagram.com/pigandwhistletales/Facebook : https://www.facebook.com/PigAndWhistleTalesTry out Buzzsprout yourself! https://www.buzzsprout.com/?referrer_id=1154066Listen to the podcast on other platforms:https://www.listennotes.com/podcasts/pig-whistle-tales-from-azeroth-gabriel-nsa902LrQVw/https://www.podchaser.com/podcasts/pig-whistle-tales-from-azeroth-1315927https://open.spotify.com/show/5ZTkLtQvRSm4PStUfZquWkhttps://podcastaddict.com/podcast/3032607The Music at the start is from Tony Catch they do many amazing cover songs for games you can find the link here:https://www.youtube.com/channel/UCHiF0dAkbpPMtQSwvAxcapQSupport the showSupport the show here: https://www.buzzsprout.com/1196870/support patreon.com/Pigandwhistle https://www.buymeacoffee.com/PigandWhistle

If you're struggling with chronic fatigue syndrome (ME/CFS) or debilitating tiredness that just won't go away, you're not alone—and you're not imagining things. Millions of people suffer from persistent fatigue that conventional medicine often fails to resolve. Fatigue and stress can make everyday tasks like working at a computer feel overwhelming, as seen in this image, which represents the experience of many with chronic fatigue syndrome (ME/CFS) At the Hedberg Institute, I'm always researching botanical compounds that support microcirculation, mitochondrial health, and immune regulation—all vital in restoring energy. That's why I formulated VascuSelect, a synergistic supplement that contains three powerful plant extracts: Ginkgo biloba, grape seed extract, and mango whole fruit powder. Let's dive into why Ginkgo biloba, in particular, stands out for those dealing with ME/CFS and how it works alongside other ingredients in VascuSelect to support your energy and vitality. An Important Study: Ginkgo Biloba for ME/CFS A recent paper published in Frontiers in Pharmacology (2022) titled “A Botanical Product Containing Cistanche and Ginkgo Extracts Potentially Improves Chronic Fatigue Syndrome Symptoms in Adults: A Randomized, Double-Blind, and Placebo-Controlled Study” sheds important light on Ginkgo's role in combating chronic fatigue. In this gold-standard clinical trial, 101 adults with ME/CFS received a botanical supplement combining Ginkgo biloba extract (120 mg/day) and Cistanche tubulosa extract (300 mg/day) or a placebo for 60 days. The results were impressive: Significant reductions in fatigue severity Improved physical performance and VO₂ max Enhanced antioxidant status and reduced oxidative stress markers Improved sleep quality and concentration Enhanced quality of life (QOL) and sexual life (SLQ) scores Decreased blood levels of lactic acid and ammonia (both fatigue biomarkers) What's particularly exciting is that Ginkgo biloba played a central role in this formulation. The authors noted that Ginkgo's flavonoids and terpenoids contribute to neuroprotection, vasodilation, and mitochondrial support, all of which are key areas of dysfunction in ME/CFS patients. This study confirms that Ginkgo biloba, known for enhancing blood flow and antioxidant activity, can play a central role in reducing the burdens of ME/CFS. How Ginkgo Biloba Helps Fight Fatigue Ginkgo biloba (standardized to 24% flavonol glycosides and 6% terpenes) is one of the most studied botanical extracts for circulatory and cognitive health. But its applications go far beyond brain support—especially for those with energy-depleting illnesses like ME/CFS. Ginkgo biloba is one of the oldest and most studied medicinal plants. It's been used for centuries in Traditional Chinese Medicine, but modern science is now validating its applications for conditions like ME/CFS, fibromyalgia, and Long COVID. 1. Improves Microcirculation Ginkgo biloba increases blood flow, especially in the small vessels of the brain and extremities. This is critical in ME/CFS, where impaired oxygen delivery to tissues can worsen fatigue. 2. Supports Mitochondrial Function Many people with ME/CFS experience dysfunctional mitochondria—the energy-producing engines of cells. Ginkgo has been shown to protect mitochondrial membranes and improve ATP production, helping the body generate more usable energy. 3. Reduces Oxidative Stress Oxidative stress is a hallmark of ME/CFS and contributes to inflammation, brain fog, and fatigue. Ginkgo's rich flavonoid profile helps neutralize free radicals and reduce oxidative damage. In the study mentioned above, participants taking Ginkgo and Cistanche showed significant increases in antioxidant enzymes like SOD and CAT. 4. Enhances Neurotransmitter Function Ginkgo biloba modulates neurotransmitters like dopamine, serotonin, and norepinephrine—chemicals that regulate mood,

On a scale of 1-10 how would you rate your Quality of Life (QOL) right now?  Today Allan Crockett returns as our guest as we rip the band aid off the question that may be bouncing off the walls of your mind, "Is this the Quality of Life that I want going forward? We take a three-leg'd approach as we start with looking at how we can generate "Time and Money" in one area of a QOL, then we discuss "Relationships" as a second leg and is our dedication to the business a higher priority than our relationships, and we end on "Purpose".  If you're lying on your death bed, are you going to be happy with how you fulfilled your purpose in life? So again, I ask, how would you rate your quality of life? Do you have all the time and money you need, are your relationship healthy, and are you fulfilling your purpose in Life? If it's all good, no need to listen on, but if one or more of those three areas are lacking… then listen in! #workingranchmagazine #ranchlife #ranching #dayweather #weather #agweather #beef #cows #livestock #cattle #cowpunchercoffee #productivity #happyranching #legacy #parasite #Norbrook #Tauramox

W odcinku 205 gadamy o wszystkim co dobre i złe w nowym Switchu, zadajemy sobie pytanie jak blisko uderzenia w ścianę jest rynek AAA i wspominamy zamerzchłe lata kiedy singlowe kampanie w FPSach były dobre i krótkie (był to rok 2016), a także pochylamy się nad ostatnimi gamepassowymi premierami, chociaż znajdzie się też miejsce na zarówno polski jak i ciasno-rycerski akcent.W sekcji VR Simplex odkrywa prawie 10 letnią grę z bohaterem, z którym w pewnym względzie może się utożsamiać, a w kulturce Defan ponownie zabierze Was w podróż po świecie kina wyrywającemu się ramom czasów.Podziękowania dla Defana za okladkę, Perki za montaż, Rudego za rozpiskę. Podziękowania dla Patronów za wsparcie, a najbardziej dla: Op1ekun, Jan Jagieła, Lisu, Janomin, Łukasz M., Tomasz Herduś, Paweł G., Uki, Mateusz "Kaduk" Kadukowski z kanału Kadukowo, Taktyki, Kosmaty dziadu z kanału 8biters.Discord MKwadrat Podcast- https://discord.gg/PafByaf9DU Discord akcji #PolishOurPrices: https://discord.gg/zvzvFp7qmEKanał Defana: https://www.youtube.com/@wsumiespoko/W co ostatnio graliśmy?(00:00:00) Start(00:00:40) Simplex(00:01:29) Perka(00:13:32) DefanNewsy naleśnikowe(00:23:45) Titanfall 3 jest prawie ukończony, albo jest halucynacją(00:28:10) Eidos Montreal chciałby zrobić Deus Exa(00:33:05) Zwolnienia Cyan(00:34:28) Strajk związku zawodowego ZeniMax(00:36:35) Movie Games i pozew w sprawie Schedule 1(00:46:00) Powraca Game Informer(00:47:29) Współtwórca Astrobot mówi że potrzeba krótszych gier(00:48:53) AC Shadows dostało patcha z funkcjami i QoL(00:51:55) Powstał mod do Halo CE “Trenchcoat”(00:54:17) Konferencja Triple-I(01:05:02) Nintendo Switch 2 pokazanyGry naleśnikowe(01:39:17) Demo Metal Eden jest fajne(01:41:53) South of Midnight - Perka, Simplex(02:01:00) Knights in Tight Spaces - Defan, Perka(02:33:44) Atomfall - Simplex, Defan(02:53:03) Sports: Renovations - RudyNewsy VR(03:14:45) Flight Simulator najlepiej sprzedającą się grą VR na PSVR2(03:17:00) Alyx na Queście 3 (tak jakby)(03:18:00) Śledzenie oczu PSVR 2 na PC(03:19:50) Apple Vision Pro 2 powstaje?Gry VR(03:20:40) Hitman PSVR2 - SimplexKulturka(03:35:17) Adolescence (Dojrzewanie), Netflix - Perka, Simplex(03:43:40) Timeless Film Festival i KONKURS - Defan(04:27:47) Platonic (Platoniczni), Apple TV+ - Simplex(04:31:06) Common Side Effects (Częste skutki uboczne) S1, Max- Simplex(04:32:29) The White Lotus (Biały Lotos) S3, Max - Simplex(04:34:45) The Pitt S1, Max- Simplex(04:36:15) Severance (Rozdzielenie) S2, Apple TV+ - Perka, SimplexSpołeczność/Publicystyka(04:46:14) Przypomnienie o nagrodach w ankiecie(04:36:34) Rozwiązanie konkursu na AC: Shadows(04:50:17) Podziękowania dla patronów(04:51:20) Ankieta/Recenzja odcinka/Komentarze na YT/Spotify(04:56:22) Spoilery z zakończenia AtomfallaKonsumpcja:MP3: https://mkwadratpodcast.pl/podcast/MKwadrat_205.mp3YouTube: https://www.youtube.com/c/MKwadratPodcastRSS: https://mkwadratpodcast.pl/feed/podcastSpotify: https://open.spotify.com/show/7e5OdT8bnLmvCahOfo4jNGiTunes: https://podcasts.apple.com/ca/podcast/mkwadrat-podcast/id1082742315twitch: https://www.twitch.tv/mkwadratpodcastInterakcja:WWW: https://mkwadratpodcast.pl/Forum: https://stareforumpoly.pl/Discord: https://discord.com/invite/PafByaf9DUFanpage: https://facebook.com/MkwadratPodcast/Grupa FB: https://www.facebook.com/groups/mkwadratpodcast/Twitter: https://twitter.com/mkwadratpodcastInstagram: https://www.instagram.com/mkwadratpodcast/Kontrybucja:Patronite: https://patronite.pl/mkwadratpodcastSuppi: https://suppi.pl/mkwadratpodcast

★今回のトーク一覧★ 0:16～「QOL爆上がり？「生活の革命」起こしてます。」 5:16～「「ETCの奇跡？」の話 」 7:39～「「まだきていないGWのリベンジをする」話」 【Twitter】https://mobile.twitter.com/Ticket_Bombers 【お便り】https://forms.gle/GpqoyGoJ8PsqsQ9t5 【Youtube】https://www.youtube.com/channel/UCdMGmOndKpEmiBbIsnrP9sQ

Hazaa! Our first balance patch of Path of Exile 2's Early Access! We played as much as we could today (launch day) before recording and, no joke, could have easily doubled the length of the episode. GGG's 0.2.0 patch is out and it's loaded with changes to fuel us for months! We hope you're enjoying Dawn of the Hunt! Thanks, as always for your listens each week. You all rock!(00:00:00) Welcome and Grip It and Rip It(00:01:00) Patrons, Drinks, and After Dark Vibes(00:04:45) GGG Apology and Calendar Confession(00:08:30) Home Repairs, Squirrels, and Skate Parks(00:12:00) Path of Exile Begins – Patch 0.2.0 Hype(00:15:00) The Reveal vs The Q&A(00:18:45) UI Improvements and Subtle Changes(00:22:00) Skill Balance and Unlisted Fixes(00:25:45) Mapping, QoL, and Controller Updates(00:30:15) Resistances, Quest Zones, and Boss Icons(00:34:00) Private Leagues and Future Content(00:39:00) League Starters and Build Discussion(00:43:00) Poison and Minion Builds in 0.2(00:47:30) Progression Speed and Campaign Thoughts(00:52:00) Loot Impressions and Gear Drops(00:57:00) Enemy Density and Pack Spacing(01:01:00) Accessibility and New Player Experience(01:05:45) GGG Direction, Trust, and Player Feedback(01:10:30) Final Thoughts and Episode Wrap-UpForever Exiled Info:www.foreverexiled.comPatreonTwitter @ForeverExiled82Path of Exile WebsiteWrecker of Days Builds ListDiscord...FE Merch StoreFE Nexus Store

This week we talk about the Osto-Ayak rewards, the latest quality of life updates, and we do a Q&A. EPISODE TIME STAMPS00:00 Intro & personal updates24:31 16-bit sounds28:04 Updated Delve boss rewards43:49 Poll 83 QOL update1:19:20 Q&A1:48:51 OutroEpisode notes:https://secure.runescape.com/m=news/behind-the-scenes-16-bit-audio?oldschool=1https://secure.runescape.com/m=news/new-delve-boss-rewards---varlamore-the-final-dawn?oldschool=1https://secure.runescape.com/m=news/poll-83-qol-changes?oldschool=1https://youtooz.com/collections/old-school-runescapeHelp buy cosplay supplies:https://throne.com/bunebapeWatch live at: https://www.twitch.tv/bunebapeJoin Our Community Discord at: https://discord.gg/44jX6yNCVKJoin our OSRS Clan!Clan: Bunebape Friend Chat: /BunebapeosrsDid you enjoy the content or have any questions? Let us know by commenting and check out more content you might enjoy at the links below.Podcast: https://anchor.fm/bunebapeInstagram: https://www.instagram.com/bunebape/?hl=enTwitter: https://twitter.com/bunebapeosrsTikTok: https://www.tiktok.com/@bunebapeosrsMerch: https://bunebape.comYoutube: https://youtube.com/bunebapeBusiness Inquiries:Bunebape@gmail.comTags:#osrs #oldschoolrunescape #osrspodcast #runescapepodcast #podcast

OFLP : Un live sans langue de bois tous les jeudis dès 19h15 sur http://twitch.tv/kahikusu► Agenda FGC et réseaux sociaux : linktr.ee/kahikusu► Bluesky : https://bsky.app/profile/kahikusu.bsky.social► https://twitter.com/kahikusu---------------------------------------------------------------0:00 : Intro + programme5:09 : Rééquilibrage et QoL pour Rivals of Aether 26:35 : Conflit entre éditeur et developpeurs de Skullgirls11:35 : L'Esport World Cup s'associe au Capcom Pro Tour 16:03 : Règles et format du nouveau Capcom Pro Tour 202523:43 : Fin de l'émission, rendez-vous jeudi 19h15 sur Twitch !

This week we talk everything announced during the Runefest Summit, the newest QOL update, and we do a Q&A. EPISODE TIME STAMPS00:00 Intro & personal updates08:22 Sailing Alpha34:42 Yama: end game duo boss54:48 Varlamore: The Final Dawn1:29:21 Summer Sweep, Deadman Mode, Blood Moon Rises1:43:25 HD/API, Project Zanaris, New CEO1:52:54 Charges update2:01:29 Q&A2:17:09 OutroEpisode notes:https://secure.runescape.com/m=news/a=3/runefest-2025-summit-summary?oldschool=1https://secure.runescape.com/m=news/a=3/behind-the-scenes-of-sailing-volume-3-sailing-alpha-launch-date---runefest?oldschool=1https://secure.runescape.com/m=news/a=3/yama---master-of-pacts?oldschool=1https://secure.runescape.com/m=news/a=3/project-zanaris---runefest-update?oldschool=1https://secure.runescape.com/m=news/a=3/varlamore-the-final-dawn---overview?oldschool=1https://secure.runescape.com/m=news/a=3/official-client-plugin-api--hd-updates?oldschool=1https://secure.runescape.com/m=news/a=3/a-new-chapter-for-jagex-welcoming-mod-north-as-ceo?oldschool=1https://secure.runescape.com/m=news/a=3/game-jam-charges-qol?oldschool=1Help buy cosplay supplies:https://throne.com/bunebapeWatch live at: https://www.twitch.tv/bunebapeJoin Our Community Discord at: https://discord.gg/44jX6yNCVKJoin our OSRS Clan!Clan: Bunebape Friend Chat: /BunebapeosrsDid you enjoy the content or have any questions? Let us know by commenting and check out more content you might enjoy at the links below.Podcast: https://anchor.fm/bunebapeInstagram: https://www.instagram.com/bunebape/?hl=enTwitter: https://twitter.com/bunebapeosrsTikTok: https://www.tiktok.com/@bunebapeosrsMerch: https://bunebape.comYoutube: https://youtube.com/bunebapeBusiness Inquiries:Bunebape@gmail.comTags:#osrs #oldschoolrunescape #osrspodcast #runescapepodcast #podcast

Join Professors Peter Nash, Philip Mease, and Laura Coates as they discuss the top publications in the world of PsA. This month, the conversation covered a discussion on the longer-term impact of bimekizumab on patient-reported outcomes, health-related QoL, and work productivity in patients with active PsA who were bDMARD-naïve or had an inadequate response to TNFis for up to 1 year.

【内容】◇掃除機でQOLアップ◇ケイくん「●●合コンに予約」◇水族館好きをアピール

ごめんなさい、方言に意味はない！というわけで、きどにちは今回は学者キドリが2024年買ってよかったモノを紹介するシンプル回です。なんかだいぶ偏りがあるというか、これ買って生活が便利になったというよりも精神的に豊かになったものの紹介ばっかりです。そういうのも含めてQOLが向上したと言っていいのかしら？？？なんてことを考えてますが、伊藤くんの前フリによって、なんか変な感じになるのも含めてよろしくお願いいたしますみんなの買ってよかったモノ教えてください↓gakushakidori@gmail.com今回紹介したもの↓・ドラゴンクエスト　メタリックモンスターズギャラリーhttps://store.jp.square-enix.com/category/263/・Ashleigh＆Burwood （アシュレイアンドバーウッド）フレグランスランプhttps://shop.liveincomfort.co.jp/c/gr39/gr33・デジタルメモ pomera（ポメラ） https://www.kingjim.co.jp/pomera/dm250/・Fender GDC-100SCE（ミニエレアコ）・YAMAHA THR10Ⅱ（ギターベース兼用アンプ）https://jp.yamaha.com/products/musical_instruments/guitars_basses/amps_accessories/thr-ii/index.html・Schlagwerkカホニート（小型カホン）https://komakitsusho.co.jp/schlagwerk/product/cajon/cajonito/・ZOOM R4 MultiTrakレコーダーhttps://zoomcorp.com/ja/jp/digital-mixer-multi-track-recorders/multi-track-recorders/r4-multitrak/・ドラゴンクエストIII そして伝説へ…https://www.dragonquest.jp/roto-trilogy/dq3/・ゼルダの伝説 知恵のかりものhttps://www.nintendo.com/jp/switch/bdgea/index.html?srsltid=AfmBOor8FidNQFIVmIUB9xqqtt9mmkOdcJLs5-xR5iGp2FUDJa3vgh4w・みんな大好き塊魂アンコール＋ 王様プチメモリーhttps://encore-welovekatamari.bn-ent.net/・Desktop Mate on Steam（初音ミク）https://store.steampowered.com/app/3301060/Desktop_Mate/・洗えるＵＳＢブランケットhttps://www.muji.com/jp/ja/store/cmdty/detail/4550584390876?sc_cid=google_pla_pj_direct_cp_14797768044_adg_160733345742_cr_none_opt_none&gad_source=1&gclid=CjwKCAiAk8G9BhA0EiwAOQxmfmkVtdJ_vt-ae14O5S4CeR7Z6BmmqPDEqGeIqfl7A1ZT2gdw-M-vFxoCMDsQAvD_BwE

The first TH17 update brings us the Multi Gear Tower, Troop Launcher, Minion Prince Metal Pants, and loads of QoL changes.Use code "corrupt" to support our guest with any in game purchases and⁠ check out his content on youtube.Timestamps:(00:00) Intro(01:43) Multi Gear Tower(07:49) Troop Launcher(16:49) New Troop and Spell Levels(24:40) Defense Levels and Supercharging(31:13) Metal Pants(36:03) Snake Bracelet and Rethinking Equipment(42:03) The Alchemist(46:37) Quality of Life and Misc(1:02:13) Listener Questions

This week we talk about another(!) Varlamore rewards feedback blog, this week's QOL updates, and we do a Q&A. EPISODE TIME STAMPS 00:00 Intro & personal updates 10:16 Varlamore feedback update 26:34 Bounty Hunter & Clog update 59:26 Q&A 1:11:36 Outro Episode notes: https://secure.runescape.com/m=news/a=13/varlamore-the-final-dawn-reward-proposal-updates?oldschool=1 https://x.com/OldSchoolRS/status/1884179654413619254?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet https://secure.runescape.com/m=news/a=13/bounty-hunter-changes-collection-log-updates--emote-improvements?oldschool=1 Help buy cosplay supplies: https://throne.com/bunebape Watch live at: https://www.twitch.tv/bunebape Join Our Community Discord at: https://discord.gg/44jX6yNCVK Join our OSRS Clan! Clan: Bunebape Friend Chat: /Bunebapeosrs Did you enjoy the content or have any questions? Let us know by commenting and check out more content you might enjoy at the links below. Podcast: https://anchor.fm/bunebape Instagram: https://www.instagram.com/bunebape/?hl=en Twitter: https://twitter.com/bunebapeosrs TikTok: https://www.tiktok.com/@bunebapeosrs Merch: https://bunebape.com Youtube: https://youtube.com/bunebape Business Inquiries: Bunebape@gmail.com Tags: #osrs #oldschoolrunescape #osrspodcast #runescapepodcast #podcast

In case you've been living under a rock, Nintendo released a, what has to be described as lackadaisical, video revealing the successor the the Switch: the aptly named Nintendo Switch 2! We go over the info we have, discuss the mouse-Joycons, talk about some of the QOL improvements, discuss the magnetic Joycon connectors, give our thoughts on Mario Kart 9, and our overall thoughts on the lack of pizzazz given to the reveal. PLUS we talk about how Metroid Prime 4 could factor into the Switch 2's launch! All this, PLUS - we have a big announcement on February 1st! Set a reminder and be sure to follow us on Bluesky to be up to date!   Visit OmegaMetroid.com!   Subscribe! Podbean x iTunes x Spotify x YouTube Support us on Patreon! Omega Metroid Patreon Buy Omega Metroid Merch! Check out our Etsy merch shop! Download the Omega Metroid Theme Song! Get the Single for Free on Bandcamp! Follow us! @OmegaMetroid x @Spiteri316 x @DoominalCross x Omega Metroid Team Member Starter Pack Chat with us in Discord! Omega Metroid Discord Advertise on the Omega Metroid Podcast!

On this week's episode of Windbreaker, Yahtzee, JM8, and Marty chat about their history with cheat codes, unlockable cheats, exploits, modern QoL features, and all that jazz Second Wind is fully independent, employee-owned and fan-funded. Consider supporting us on Patreon for as little as $1/month at ⁠patreon.com/SecondWindGroup

Ryan and I have been wanting to do an episode of QOL together for years. And finally... we did it! Ryan's motto is "If you have a dream, don't let anything stop you," and you can add "Dream big, work harder," to that philospohy. His store on Lasalle is just filled with great messages. Come along and listen to how Ryan's positivity is infectuous.

In a conversation with CancerNetwork®, Rachel A. Millstein, PhD, MHS; Loren Winters, NP; and Amy Comander, MD, discussed their article titled Implementing a Multidisciplinary Lifestyle Medicine Clinic for Cancer Survivorship, which was published in the November 2024 issue of ONCOLOGY®. The authors detailed the implementation of a novel oncology-based multidisciplinary lifestyle medicine clinic that may help enhance the quality of life (QOL) among survivors of cancer. Millstein is a psychologist in the Behavioral Medicine Program and an assistant professor in the Department of Psychiatry at Massachusetts General Hospital. Winters is an oncology nurse practitioner and assistant director of the Lifestyle Medicine Program at Massachusetts General Hospital. Comander is the medical director of Mass General Cancer Center-Waltham, director of the Breast Oncology Program at Newton-Wellesley Hospital, and director of the Lifestyle Medicine Program at Massachusetts General Hospital. Millstein outlined the rationale for this publication on the development of a multidisciplinary lifestyle medicine clinic, highlighting a need to boost general awareness and support for lifestyle medicine consultations and health behavior change in cancer survivor care. Winters then explained how the multidisciplinary clinic works in alignment with 6 key pillars of lifestyle medicine, as team members aim to promote physical activity, plant-predominant diets, restorative sleep, stress management, avoidance of risky substances, and social connections to enhance QOL among cancer survivors. Additionally, Comander highlighted how the lifestyle medicine program optimizes health and well-being by matching patients to the specific services they require, which may include the help of team members such as board-certified physicians, nurse practitioners, registered dietitians, and clinical psychologists. Millstein and Winters then detailed the improvements in health behaviors associated with 2 patient cases at their program, demonstrating the potential benefits of implementing broad and diverse lifestyle medicine tools in oncology-supportive care. Looking ahead, Comander described the importance of addressing gaps in education, a lack of programs focused on areas such as weight management, and other barriers to the implementation of lifestyle medicine in oncology care. Finally, each author expressed her hope to see more colleagues, clinics, and programs incorporate lifestyle medicine as part of elevating QOL among survivors of cancer. The authors invite listeners to contact them if they would like to find ways to implement lifestyle medicine in their respective centers.

CancerNetwork® spoke with Natasha Bahri, MD, MS, and Daneng Li, MD, about their Hot Topics article titled Casting a Wide NET: When Is the Optimal Time for 177Lu-Dotatate Treatment?, which was published in the November 2024 issue of ONCOLOGY®. Their article focused on findings related to the use of 177Lutetium-Dotatate (177Lu-dotatate; Lutathera) in patients with neuroendocrine tumors (NETs) and whether these data supported the use of the novel radioligand therapy for this population. Bahri is a PGY-5 chief fellow in Medical Oncology and Hematology at City of Hope National Medical Center in Duarte, California. Li is an associate professor in the Department of Medical Oncology & Therapeutics Research at City of Hope Comprehensive Cancer Center in Duarte, California, and a gastrointestinal editorial board member of ONCOLOGY. Bahri and Li discussed findings from the phase 3 NETTER-1 trial (NCT01578239) assessing 177Lu-dotatate for those with inoperable, locally advanced or metastatic, grade 1/2 midgut NETs following progression on long-acting repeatable octreotide therapy. Although these findings established a significant efficacy signal with the radioligand therapy, Li noted that questions remained regarding the sequencing of 177Lu-dotatate alongside other therapies in the treatment landscape. The conversation also covered efficacy, safety, and quality-of-life (QOL) data from the phase 3 NETTER-2 trial (NCT03972488), in which investigators assessed high-dose octreotide with or without 177Lu-dotatate among patients with locally advanced or metastatic, well-differentiated, somatostatin receptor–positive gastroenteropancreatic NETs. Although data showed improvements in efficacy with the 177Lu-dotatate combination, there did not appear to be significant differences regarding QOL outcomes between arms. “We're waiting for further long-term follow-up information as there was no difference in the QOL metrics. It's important to think about how these patients' goals align with the therapy that we're giving, and if we're not seeing a difference in the quality of life quite yet, [we need to] look at individual patients, see what their goals are, and match them up to the therapy that we're giving them,” Bahri stated. Although the NETTER-1 and NETTER-2 trials demonstrate “great” results associated with efficacy end points such as progression-free survival, the authors noted that it is crucial to weigh these benefits with the potential toxicities when determining suitable candidates for treatment with 177Lu-dotatate. “There's a lot of nuances in terms of who is the ideal patient that's going to maximally benefit [while] minimizing any risk of serious toxicity in those patients. As a result of that, we're helping to improve their outcomes to the highest bars possible, whether it's quality of life or survival,” Li concluded. References 1.        Strosberg J, El-Haddad G, Wolin E, et al; NETTER-1 Trial Investigators. Phase 3 trial of 177Lu-Dotatate for midgut neuroendocrine tumors. N Engl J Med. 2017;376(2):125-135. doi:10.1056/NEJMoa1607427 2.        Singh S, Halperin D, Myrehaug S, et al; NETTER-2 Trial Investigators. [177Lu]Lu-DOTA-TATE plus long-acting octreotide versus high-dose long-acting octreotide for the treatment of newly diagnosed, advanced grade 2-3, well-differentiated, gastroenteropancreatic neuroendocrine tumours (NETTER-2): an open-label, randomised, phase 3 study. Lancet. 2024;403(10446):2807-2817. doi:10.1016/S0140-6736(24)00701-3

Stephen Popovich, President/CEO of Theora Care, is an innovator in the data communications field with more than 30 years of experience. Popovich is a serial entrepreneur, was Co-Founder/CEO of Inside Out Networks with USB technology products used in medical, military, and other commercial applications that he sold to Digi International (NASDAQ: DGII). In 2015, he founded Theora Care to provide caregiving solutions based on AI, neural networking and Ultra Wideband (UWB) technologies. These advanced situational awareness products maximize quality of life (QoL) for older adults as well as integrating caregiver connectivity and support into its product designs.https://www.seniorcareauthority.com/resources/boomers-today/

Nachdem Square mit Octopath Traveler und zuletzt mit Star Ocean The Second Story R zwei der mit Abstand schönsten Pixelspiele der letzten Zeit herausgebracht hat, hat man sich intern nun einem anderen Rollenspielfranchise gewidmet. Mit Dragon Quest III HD-2D Remake schnappte man sich nun einen Titel aus dem Jahre 1988 und hat diesen ähnlich wie die beiden zuletzt erschienenen Spiele grafisch wunderschön aufpoliert. Auch hier funktioniert die Welt in ihrer charmanten 2D-HD Pixel Optik wirklich gut und oftmals, gerade wenn es Nacht ist oder der eine oder andere Lichteffekt durchscheint, war ich sehr beeindruckt von der Ästhetik. Das altbackene Rollenspielflair von damals bekam ein paar Quality of Life Features wie z.B einen Zielmarker für die nächste Reise. Allerdings hätte ich mir gerade im Speicherbereich etwas mehr QoL gewünscht, auch von den Kämpfen her bleibt bis auf die Optik alles beim Alten. Die vielen Random Encounter und einiges an Grinding könnten heutzutage den einen oder anderen Spieler, der das erste Mal mit der Serie in Kontakt kommt, allerdings etwas abschrecken...

Everything you need to know while we patiently await the Town Hall 17 Update and the introduction of the first new hero in years - The Minion Prince. Bash joins the 3 timers club to give us the scoop (use code BASH) and dish out tips to get the most out of the Prince, the Lab Assistant, Throwers, Firespitters, and everything else coming to a Home Village near you. Links: ClashBashing Youtube ClashBashing Discord Timestamps: (00:00) Intro and Farewell to TH16 (08:36) Minion Prince (21:34) Henchmen Puppet and Dark Orb Equipment (25:30) QoL, TH8 Queens, and the Lab Assistant (36:33) IF YOU ONLY LISTEN TO ONE THING BEFORE THE UPDATE MAKE IT THIS (38:03) TH17 Offense (41:57) Revive Spell (44:44) Throwers and the 55 Space CC (46:44) TH17 Defenses (52:24) More like Stupidcharges (59:51) Listener Questions and Goodbye

We missed last week and it feels like Capital Games changed EVERYTHING. We talk about the two new kits: Huyang and Rey (Dark Side Vision), as well as the QoL and UI changes to the game. Plus: to many, the new Era system and Episode economy feel weird and bad, but what’s the bigger picture? […] The post Galactic War Report – Episode 412: Rey (Kylo’s Version) appeared first on RADIO FREE TATOOINE.

The following question refers to Section 7.4 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.The question is asked by the Director of the CardioNerds Internship Dr. Akiva Rosenzveig, answered first by Vanderbilt AHFT cardiology fellow Dr. Jenna Skowronski, and then by expert faculty Dr. Clyde Yancy.Dr. Yancy is Professor of Medicine and Medical Social Sciences, Chief of Cardiology, and Vice Dean for Diversity and Inclusion at Northwestern University, and a member of the ACC/AHA Joint Committee on Clinical Practice Guidelines.The Decipher the Guidelines: 2022 AHA / ACC / HFSA Guideline for The Management of Heart Failure series was developed by the CardioNerds and created in collaboration with the American Heart Association and the Heart Failure Society of America. It was created by 30 trainees spanning college through advanced fellowship under the leadership of CardioNerds Cofounders Dr. Amit Goyal and Dr. Dan Ambinder, with mentorship from Dr. Anu Lala, Dr. Robert Mentz, and Dr. Nancy Sweitzer. We thank Dr. Judy Bezanson and Dr. Elliott Antman for tremendous guidance.Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. American Heart Association's Scientific Sessions 2024As heard in this episode, the American Heart Association's Scientific Sessions 2024 is coming up November 16-18 in Chicago, Illinois at McCormick Place Convention Center. Come a day early for Pre-Sessions Symposia, Early Career content, QCOR programming and the International Symposium on November 15. It's a special year you won't want to miss for the premier event for advancements in cardiovascular science and medicine as AHA celebrates its 100th birthday. Registration is now open, secure your spot here!When registering, use code NERDS and if you're among the first 20 to sign up, you'll receive a free 1-year AHA Professional Membership! Question #37 Mr. S is an 80-year-old man with a history of hypertension, type II diabetes mellitus, and hypothyroidism who had an anterior myocardial infarction (MI) treated with a drug-eluting stent to the left anterior descending artery (LAD) 45 days ago. His course was complicated by a new LVEF reduction to 30%, and left bundle branch block (LBBB) with QRS duration of 152 ms in normal sinus rhythm. He reports he is feeling well and is able to enjoy gardening without symptoms, though he experiences dyspnea while walking to his bedroom on the second floor of his house. Repeat TTE shows persistent LVEF of 30% despite initiation of goal-directed medical therapy (GDMT). What is the best next step in his management?AMonitor for LVEF improvement for a total of 60 days prior to further interventionBImplantation of a dual-chamber ICDCImplantation of a CRT-DDContinue current management as device implantation is contraindicated given his advanced age Answer #37 Explanation Choice C is correct. Implantation of a CRT-D is the best next step. In patients with nonischemic DCM or ischemic heart disease at least 40 days post-MI with LVEF ≤35% and NYHA class II or III symptoms on chronic GDMT, who have reasonable expectation of meaningful survival for >1 year,ICD therapy is recommended for primary prevention of SCD to reduce total mortality (Class 1, LOE A). A transvenous ICD provides high economic value in this setting, particularly when a patient's risk of death from ventricular arrhythmia is deemed high and the risk of nonarrhythmic death is deemed low. In addition, for patients who have LVEF ≤35%, sinus rhythm, left bundle branch block (LBBB) with a QRS duration ≥150 ms, and NYHA class II, III, orambulatory IV symptoms on GDMT, cardiac resynchronization therapy (CRT) is indicated to reduce total mortality, reduce hospitalizations, and improve symptoms and QOL. Cardiac resynchronization provides high economic value in this setting. Mr.

In this episode of QOL we visit with Sue Scherzingerat Gourmet World. From cold cuts to cheese, and chocolates to cookies, this is the place to go for all kinds of European goodies. Yes, I think you can do all your holiday shopping right here! There are always sandwiches (served with a snappy Knax pickle) and soup for a satisfying lunch. Let's explore the aisles and show cases with Sue and see the house-made cakes and desserts. Check out their website to see it all: www.gourmetworld.ca

Ah yes, the sweet tooth, it can get us into trouble, always telling us to go ahead and eat all of those delicious sugar-laced yummies that we know we really shouldn't. From bacteria and plaque eroding the enamel on our teeth contributing to tooth decay, to the excess sugar contributing to obesity, that sweet tooth doesn't do us any favors. But the worst part of sugaraholism is a shortened lifespan and low QOL (quality of life).

Ep. 11 A Spine Surgeon Who Refuses to Quit: A Battle for Better Spine Care, Evalina Burger, MD   In this episode of The Spine Pod, hosts Courtney Schutze and Brady Riesgraf sit down with Dr. Evalina Burger, an orthopedic spine surgeon at the UCHealth Spine Center - Anschutz Medical Campus. Dr. Burger recounts her transformative journey from South Africa to the United States, where she has established herself as a leader and innovator at the forefront of spine care. She goes on to share about her own spinal cord injury and how that has changed her perspective and approach to spine surgery. Dr. Burger specializes in complex spine surgery, deformity and scoliosis, and has also been an outspoken advocate and pioneer for motion-preserving spine implants. She has been an investigator in multiple FDA clinical trials, including the TOPS facet replacement from Premia Spine, showing her commitment to research and improving patient care. With her background and incredible personal journey, Dr. Burger has prioritized patient quality of life and is constantly searching for new ways to improve long-term outcomes for her patients.   In this episode you'll learn: The importance of new perspectives in order to innovate on currently held treatment methods. How quality of life (QoL) is becoming the new outcome metric that providers are beginning to evaluate their surgical outcomes. Where motion preserving spine surgeries fit into the care continuum and how we can begin to give patients longer lasting results. How spinal fusion has been utilized by surgeons for many decades and how that approach as a primary treatment method is beginning to shift. The importance of resilience on growth and overcoming hurdles in life; how to create great outcomes from challenging situations. How the treatment for leg and/or back pain is beginning to change and what new options are becoming available to patients seeking spine care.   As someone who dreamed about being a surgeon as a child, Dr. Burger has accomplished that and much more throughout her years in surgery. Currently holding the title of Department Chair of Orthopedics at the University of Colorado School of Medicine, she has established herself as a leader and role model within the spine community. Dr. Burger has also contributed more than 95 peer-reviewed journal articles, proving her lasting commitment to research and patient outcomes.   Whether you're a patient, industry professional, or provider, this episode provides a breadth of experience and knowledge that you won't want to miss.   Learn more about Dr. Burger and UCHealth Spine Center - Anschutz Medical Campus: Website: https://www.uchealth.org/provider/evalina-burger-van-der-walt-md/ LinkedIn: https://www.linkedin.com/in/evalina-burger-145a7835/   You can find The Spine Pod on all Podcast Streaming Platforms, including: YouTube: https://www.youtube.com/channel/UCcA8vODr8pDabWImOrHv3ZQ  Spotify: https://open.spotify.com/show/0DBzWfV... Apple Podcasts: https://podcasts.apple.com/us/podcast... Amazon Music: https://music.amazon.com/podcasts/98f... iHeart Radio: https://www.iheart.com/podcast/269-th...   Follow The Spine Pod on Facebook to learn more about the latest episodes and happenings in the world of motion preservation: https://www.facebook.com/profile.php?...  

Author Laura Tamblyn Watts talks about her recently published "Let's Talk About Aging Parents" here on QOL. This essential guide is not just a unique "how to" but you can jump all around the table of contents and find something you are dealing with right now. Turn to any page and she offers valuable insight - and even humour - in addressing difficult situations.

In this episode of SurgOnc Today®, Dr. Patrick Sullivan is joined by Dr. Nicole Lopez and Dr. César Reátegui to discuss diverting ostomy. Current practice guidelines suggest that diverting ostomy is the standard of care in surgical management of rectal cancer after neoadjuvant therapy to minimize the risk of clinically significant leak which can then result in permanent colostomy. However, the risk of anastomotic leak after neoadjuvant chemoradiation ranges from 4-12% suggesting that most patients have unnecessary ostomy and additional surgery. With improvement of surgical techniques, utilization of robotic surgery and recent adoption of more TNT approaches, selective use of diverting ostomy will lead to improvement in QOL and decrease in health care costs with minimal impact on incidence of permanent colostomy.

Want to learn more about garlic? How to grow it? How to cook with it? How to enjoy it? Yes, even where to get garlic ice cream (the answer is at the Ukrainian Centre in Sudbury). My guest in this episode of QOL is Peter McClusky, author of Ontario Garlic: The Story from Farm to Festival. Peter shares garlic's history - starting in central Asia - how it was shunned and now embraced. While Sudbury has its festival at the end of August, Toronto holds it celebration of all things garlic on Sunday September 29th. Visit their website www.torontogarlicfestival.ca for a full list of vendors, participating restaurants... Attend and try garlic desserts, garlic beer, and even expert advice on "... how to keep vampires at bay."

The draft order:Sophia AmbrusoNayan AroraSwapnil HiremathAC GomezJoel TopfEditor Nayan AroraShow NotesPrevious drafts:2021 KDIGO Hypertension —Joel, Sophia, Swap, Nayan, Josh2021 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan, Jennie2022 The ISPD Peritonitis Guideline— Joel, Sophia, Swap, Nayan2022 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan2023 ASN Kidney Week Draft—Joel, Sophia, Swap, Nayan, AC, Josh2024 KDIGO CKD Clinical Practice Guideline —Joel, Sophia, Swap, Nayan, Josh, ACThe guidelineThe NephJC discussion Part 1 | Part 2First RoundSophia's Pick 3.7.1 We recommend treating patients with type 2 diabetes (T2D), CKD, and an eGFR ≥20 ml/min per 1.73 m2 with an SGLT2i (1A).Not Nayan's Pick 3.7.3: We suggest treating adults with eGFR 20 to 45 ml/min per 1.73 m2 with urine ACR

In this episode, Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLD; Marlyn J. Mayo, MD; and Brenda Remo discuss the patient experience with cholestatic pruritus in PBC.Listen to their conversation on how people describe the experience of cholestatic pruritus, the extent to which pruritus negatively affects quality of life, and the importance of educating healthcare professionals on this important symptom of PBC.Presenters:Stuart C. Gordon, MD, FACP, FACG, AGAF, FAASLDProfessor of MedicineWayne State University School of MedicineDirector, Division of HepatologyHenry Ford Health Detroit, MichiganMarlyn J. Mayo, MDProfessor of Internal MedicineDivision of Digestive & Liver DiseasesUniversity of Texas SouthwesternDallas, TexasBrenda RemoPerson living with PBCDownloadable slides: https://bit.ly/3LHHiufProgram: https://bit.ly/4fBLQ3lTo get access to all of our new podcast episodes, subscribe to the CCO podcast channels on Apple Podcasts, Google Podcasts, or Spotify.

When the cold of the toad seeps into your bones, you know you've had a bad day. Or did you? maybe not after this QOL minigame changes get added to the game! Join the boys this week as they go over QOL Blog 82 which covers some much needed changes to some of your favorite minigames in OSRS!

With 3.25 , Settlers of Kalguur, around the corner, GGG is starting to really pump out the teasers! Next week will be the full reveal, but the number of QoL changes coupled with some currency modifications are definitely getting us quite excited! GGG definitely seems keen on Path of Exile one maintaining its relevancy! We are excited for the reveal next week and had a great time talking about the teasers to tide us over! Thank you for your listens this week and for your support! We hope you enjoy the conversation and we'll see you next week for the full reveal!After Dark 249: Technical Difficulties Forever Exiled Info:www.foreverexiled.comPatreonTwitter @ForeverExiled82Path of Exile WebsiteWrecker of Days Builds ListDiscord...FE Merch StoreFE Nexus Store

✩ Audio Version ✩ ► https://superderekrpgs.com/hitpoint/ SOCIAL LINKS --------------------------------------------------- ✩ Derek ✩ ►Twitter: https://twitter.com/SuperDerekRPGs ►Twitch: https://www.twitch.tv/SuperDerekRPGs ►Discord: https://discord.me/superderek✩ Baku ✩ ►Twitter: https://www.twitter.com/BakusanOG►Twitch: https://www.twitch.tv/BakusanOG►YouTube: https://www.youtube.com/WeebSauce ►Discord: https://discord.me/ABCUPCOMING RELEASES ---------------------------------------------------0:00:00 Welcome Back to Hit Point!0:01:24 Intro0:02:02 Baku how are you doing?0:04:08 HitPoint Live Showcase Recap Last Week's Comments:0:05:40  Comment 1: A Playstation financial report that showed...0:09:55  Comment 2: I see comment's all the time that say gaming is in a horrible state, but ...0:15:48  Comment 3: I swear I don't care about graphics...0:22:11 Voice-Mail: Does reaching a Level with which you can beat the game stop you finish it? Upcoming Releases This Week 0:34:41 Elden Ring - Shadow of the Erdtree0:40:04 Thistlemine0:43:17 Shin Megami Tensei V: Vengeance New Game Announced:0:55:45 Rusty Rabbit1:00:52 Metal Slug Tactics1:05:45 Visions of Mana1:18:04 Lollipop Chainsaw RePop Industry News:1:22:21 Like a Dragon Live Action Adaption on Amazon Prime1:29:53 Capcom Survey results. Q1 : Capcom games do you like the best?1:38:52 Capcom Survey results. Q2 : Favorite Capcom character?1:43:19 Capcom Survey results. Q3 : What do you look for in Capcom games?1:44:15 Capcom Survey results. Q4 : What image do you have of Capcom?1:44:35 Capcom Survey results. Q5 : From what would you like to see get a sequel or new game?1:47:57 Capcom Survey results. Q6 : What would you like a remake from?1:50:45 Capcom Survey results. Q7 : What was the first Capcom game you played?1:54:27 Capcom Survey results. Q8 : What Capcom games influenced you the most?1:55:40 Capcom Survey results. Q9 : A complaint you would like to share with Capcom?1:58:27 Capcom Survey results. Q10: We welcome all your support for Capcom.1:59:02 Capcom Survey results. TakeawayResponding to Super Chats & Outro 2:02:09 Super Chat  1: How do you usually feel when a game isn't really hooking you.2:08:59 Super Chat  2: I haven't been to this channel in what feels like forever.2:09:23 Super Chat  3: Our armor weakens over time. There's nothing wrong with either of you.2:11:05 Super Chat  4: If you can survive the first cave in Lunar SSS, you can make it through Elden Ring.2:12:20 Super Chat  5: Speaking of bunnies, are you getting Bunny Garden?2:13:19 Super Chat  6: How many folks dropped the bag on the Collector's Edition (Visions of Mana)?2:14:43 Super Chat  7: If you day-one the heck out of many you my get 4 PS5 controllers ready.2:17:55 Super Chat  8: Do either of you have any tips to calm down your gamer rage/anger when you reach a frustrating part in a game?2:21:14 Super Chat  9: Where is the complete Trails collection?2:23:50 Super Chat 10: Was Dominion in charge of reporting the Capcom voting data? 2:24:13 Super Chat 11: BoF 1-2 with an HD-2D treatment, while BoF 3-4 get remastered for modern consoles with some QoL. Let's make it happen.2:25:24 Super Chat 12: At what point does a needed investment transform into a sunk-cost fallacy? 2:28:36 Outro

Guru Sonpavde describes the efficacy of chemotherapy with nivolumab in lymph node only 1st line UC patients. Tom describes the QOL data for EV pembro.

Join me for a summary looking at fixed versus removable functional appliances. This podcast sheds light on recent research comparing the main two types of functional appliances, which appliance offers the most advantages, and what patients think about the two appliance types. This was a lecture given by Ama Johal at last year's British Orthodontic Conference, where the most recent evidence carried out by his PhD student Moaiyad Pacha.      Moaiyad Pacha's RCT 2023 – received Dewel 2024 clinical research award ·      Hanks Herbst Vs Modified Twinblock o   Rollo bands o   Expansion o   No fixed appliances o   Incremental advancement – no evidence to support but patient-centred ·      Overjet correction: More effective Herbst at 7mm Vs 5.8mm Twinblock , ·      Molar and skeletal changes: no difference o   Twinblock = greater residual overjet after treatment p=0.2 ·      Dental changes: Herbst advance lower incisor greater 3mm Vs 1mm ·      Failure to complete: 17% Herbst Vs 37% twin block o   3 times greater likelihood of discontinue treatment OR 2.8 ·      Treatment duration: longer with Twinblock 1.5 months 8.8 Vs 10.3, and quicker rate of correction with Herbst ·      Chairside time : Greater than Twinblock 2.7 hours longer, 7.6 Vs 4.9 ·      Emergency appointments greater with Hanks Herbst 2.7 Vs 0.3 o   Herbst mainly ·      Severe complications = same 0.5 o   Severe complications – previously defined as involving lab work or break in appliance wear from Pasha's SR 2020     Advantage of Hanks Herbst ·      Greater completion of treatment, 3 times less likely to discontinue ·      Quicker rate of correction, shorter duration,   Disadvantages ·      Greater chairside time of nearly 3 hours ·      Greater emergency appointments, each patient needing 2-3 emergency appointments   Qualitative ·      Both appliances – very negative to QoL and daily life ·      Aesthetic and self-image – worse with Twinblock ·      Patient preference – Herbst o   Due to non-compliance and likely to get to the end ·      Positive Twinblock is flexible and easier to eat   Conclusion was profound ·      Patients prefer Herbst, based on aesthetics, self image and non-compliance ·      Clinicians are likely to prefer Twinblock, quicker, easier, less emergencies   Time to reconsider, and having both options, as well as both discussing of clinician Vs patient preferences,  should decide which appliance

Round II: F I G H T!! Actually, wait, maybe don't fight! Maybe think of some seriously awesome QOL perks for the last 10 skill capes AND the other major capes of accomplishment in OSRS! Join the boys this week as they finish off the list of skill cape improvements they would make if they could change them however they wanted. Want to read along as they go? Here's the link to their changes in a spreadsheet! https://docs.google.com/spreadsheets/d/1TDiHWtYn4SnqEgY6q1X4bBllLG_HKdZRBazF9dW_Tt0/edit?usp=sharing

TOGETHER WE ARE STRONGER  - 1,400 strong, thank you Jess & team. https://curesyngap1.org/blog/syngap1-census-2024-update-61-in-q1-2024-total-1400/  - Stoke webinar: one of the most important considerations for deciding which disease to work on was, “…how strong is the patient advocacy group?”   - Stoke CMO Barry Ticho, MD, PhD, FACC during webinar 4/2/24 to discuss findings of STK-001   WELCOME AND CONNECT  - New parents are coming fast, reach out to them, tell them how much hope to have.  - Connect, connect, connect.   - San Diego next week: https://curesyngap1.org/resources/movies/jaxon/   - Hope https://curesyngap1.org/blog/my-syngap1-drive-a-thon-hope4thecure/ - TU to Emily Barnes who is at FasterCures meeting today in Boston, see #S10e98 to see my thoughts about this workshop https://www.youtube.com/watch?v=iOLjUdVUtqo   TEAM IS GROWING  BOARD - https://www.eurekalert.org/news-releases/1038978  CSO - https://www.eurekalert.org/news-releases/1040061  COO - You?   PRESS  - UK https://www.channel4.com/news/govt-send-funding-boost-still-billions-short-says-tory-mp-with-affected-family/  - GA https://www.gpb.org/news/2024/04/03/80-of-rare-diseases-are-genetic-thats-why-whole-genome-sequencing-can-help/    What does my genetic report mean?  We wrote a blog, but as I've had this conversation a few dozen times, my answer is simpler now.  Is it missense or is it truncating?  If missense, do more research, if truncating, it is in the first 4 exons (p. Address of 129 or lower). Who else has it?  Look on ClinVar and call SRF. Blog: https://curesyngap1.org/blog/understanding-your-genetic-report-with-syngap1-a-rare-disease/   STUDIES https://curesyngap1.org/blog/my-syngap1-drive-a-thon-hope4thecure/  CHOP: ENDD@chop.edu  Adults:  - Press Release: https://www.eurekalert.org/news-releases/1040062  - Study Info:  https://drive.google.com/file/d/1tOdodcV7E5ROOHWyLn8a48x1WNBOr-U2/view  QOL: https://Syngap.Fund/QOL24 39 and counting.   #Sprint4Syngap 2024 Total: $168,572 from 347 people Tavilla: $126,385 from 62 Big thanks to them and all teams especially those already over $1k, Phoebe, Kaia, Louie, Kiera, Theo, Hadley & Gracyn. https://curesyngap1.org/events/featured/sprint4syngap-2024/ https://givebutter.com/ALjJXJ   REPURPOSING  - NAL, blog coming.  - Ravicti, enrolled, and blog on Butyrate coming.  - Nortriptyline, has been game changing, discussing a larger trial.   REFLECTIONS  - Family Medical Leave Act #FMLA https://www.dol.gov/general/topic/benefits-leave/fmla  - Homeschooling… again, avoid the kneejerk.  See #S10e64 https://www.youtube.com/watch?v=01uhSjxGgGE    - Tony update.  Grateful and grieving.   SOCIAL MATTERS 967 Subscribers on YouTube.  https://www.youtube.com/@CureSYNGAP1  3,483 Subscribers on LinkedIn.  https://www.linkedin.com/company/18940628/admin/feed/posts/ Socials matters so we can find more people, like this: https://curesyngap1.org/blog/an-emotional-journey-begins-after-a-syngap1-diagnosis/    Podcasts, give all of these a five star review! SRF Channel - https://podcasts.apple.com/us/channel/syngap1-podcasts-by-srf/id6464522917   Episode 138 of #Syngap10 - April 4, 2024 #epilepsy #autism #intellectualdisability #id #anxiety #raredisease #epilepsyawareness #autismawareness #rarediseaseresearch #SynGAPResearchFund #CareAboutRare #PatientAdvocacy #GCchat #Neurology #GeneChat #F78A1 #CureSYNGAP1

Genetic Therapy Companies (ignoring small molecules, see our pipeline here https://curesyngap1.org/syngap1-related-disorder-therapeutic-pipeline/)    Stoke Therapeutics #StokedAboutStoke Presser: https://investor.stoketherapeutics.com/news-releases/news-release-details/stoke-therapeutics-announces-landmark-new-data-support-potential  I did call this in #S10e111 https://youtu.be/i6EZUrqsn2g?si=RN3SLR2vHCjgAiGt&t=706  This study started in #S10e83 https://www.youtube.com/watch?v=7uK2dCs53Ew    Praxis Precision Medicines https://investors.praxismedicines.com/news-releases/news-release-details/praxis-precision-medicines-provides-corporate-update-and-11    Longboard Pharma  https://ir.longboardpharma.com/news-releases/news-release-details/longboard-pharmaceuticals-reports-full-year-2023-financial    Studies https://curesyngap1.org/blog/my-syngap1-drive-a-thon-hope4thecure/  CHOP: ENDD@chop.edu  Adults: https://drive.google.com/file/d/1tOdodcV7E5ROOHWyLn8a48x1WNBOr-U2/view  QOL: https://Syngap.Fund/QOL24       Fundraisers 247 supporters have us at $79k Team Tavilla is over half of that at $47k Big thanks to them and all teams especially those already over $1k, Phoebe, Kiera, Kaia & Gracyn. Rifton bike for S4S anyone at $500+.  247 Supporters! https://curesyngap1.org/events/featured/sprint4syngap-2024/ https://givebutter.com/ALjJXJ   Social Matters 953 Subscribers on YouTube.  https://www.youtube.com/@CureSYNGAP1  Socials matters so we can find more people, like this: https://curesyngap1.org/blog/an-emotional-journey-begins-after-a-syngap1-diagnosis/    Podcasts, give all of these a five star review! SRF Channel - https://podcasts.apple.com/us/channel/syngap1-podcasts-by-srf/id6464522917 Episode 137 of #Syngap10 - March 26, 2024 #epilepsy #autism #intellectualdisability #id #anxiety #raredisease #epilepsyawareness #autismawareness #rarediseaseresearch #SynGAPResearchFund #CareAboutRare #PatientAdvocacy #GCchat #Neurology #GeneChat #F78A1 #CureSYNGAP1

That's it! It's here! 3.24's Necropolis has been fully revealed! The patch notes are out, Json data is out, and the Q&A has been fully dissected. GGG has done it again! The league looks amazing, the core of Path of Exile looks amazing, and the Quality of Life looks amazing. We can't wait to play and see what the QoL feels like when we're in the groove. We hope you enjoyed this unedited episode of Forever Exiled. We love your faces! Thanks so much for your support each week!Forever Exiled Info:www.foreverexiled.comPatreonTwitter @ForeverExiled82Path of Exile WebsiteWrecker of Days Builds ListDiscord...FE Merch StoreFE Nexus Store

In episode 232 of Forever Exiled, GGG gave us a ton to talk about! 3.23 Affliction is almost gone for good (& what a great league it was), 3.24 Necropolis looks to be the QoL league of a lifetime, Path of Exile crafting is changing up a bit, and of course where would we be without a few theories and hypotheses. Thanks for tuning in each week! We love your faces.Forever Exiled Info:www.foreverexiled.comPatreonTwitter @ForeverExiled82Path of Exile WebsiteWrecker of Days Builds ListDiscord...FE Merch StoreFE Nexus Store

The following question refers to Section 13 of the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.The question is asked by Western Michigan University medical student and CardioNerds Intern Shivani Reddy, answered first by Mayo Clinic Cardiology Fellow and CardioNerds Academy Faculty Dr. Dinu Balanescu, and then by expert faculty Dr. Harriette Van Spall.Dr. Van Spall is an Associate Professor of Medicine, cardiologist, and Director of E-Health at McMaster University. Dr Van Spall is a Canadian Institutes of Health Research-funded clinical trialist and researcher with a focus on heart failure, health services, and health disparities.The Decipher the Guidelines: 2022 AHA / ACC / HFSA Guideline for The Management of Heart Failure series was developed by the CardioNerds and created in collaboration with the American Heart Association and the Heart Failure Society of America. It was created by 30 trainees spanning college through advanced fellowship under the leadership of CardioNerds Cofounders Dr. Amit Goyal and Dr. Dan Ambinder, with mentorship from Dr. Anu Lala, Dr. Robert Mentz, and Dr. Nancy Sweitzer. We thank Dr. Judy Bezanson and Dr. Elliott Antman for tremendous guidance.Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. Question #32 Palliative and supportive care has a role for patients with heart failure only in the end stages of their disease. TRUE FALSE Answer #32 Explanation The correct answer is False Palliative care is patient- and family-centered care that optimizes health-related quality of life by anticipating, preventing, and treating suffering and should be integrated into the management of all stages of heart failure throughout the course of illness. The wholistic model of palliative care includes high-quality communication, estimation of prognosis, anticipatory guidance, addressing uncertainty, shared decision-making about medically reasonable treatment options, advance care planning; attention to physical, emotional, spiritual, and psychological distress; relief of suffering; and inclusion of family caregivers in patient care and attention to their needs during bereavement. As such, for all patients with HF, palliative and supportive care—including high-quality communication, conveyance of prognosis, clarifying goals of care, shared decision-making, symptom management, and caregiver support—should be provided to improve QOL and relieve suffering (Class 1, LOE C-LD). For conveyance of prognosis, objective risk models can be incorporated along with discussion of uncertainty since patients may overestimate survival and the benefits of specific treatments – “hope for the best, plan for the worst.” For clarifying goals of care, the exploration of each patient's values and concerns through shared decision-making is essential in important management decisions such as when to discontinue treatments, when to initiate palliative treatments that may hasten death but provide symptom management, planning the location of death, and the incorporation of home services or hospice. It is a Class I indication that for patients with HF being considered for, or treated with life-extending therapies, the option for discontinuation should be anticipated and discussed through the continuum of care, including at the time of initiation, and reassessed with changing medical conditions and shifting goals of care (LOE C-LD). Caregiver support should also be offered to family members even beyond death to help them cope with the grieving process. A formal palliative care consult is not needed for each patient, but the primary team should exercise the above domains to improve processes of care and patient outcomes. Specialist palliative care consultation can be useful to improve QOL and relieve suffering for patients with heart failure—particularly tho...

The boys review Season 2's litany of QOL changes and, of course, some of the actual new content. 00:00:00 - Teaser 00:01:02 - Intro & announcements 00:09:04 - Preamble 00:18:08 - The good 00:58:18 - Sponsored by SBMMOFF 00:59:56 - The good contd. 01:21:11 - The bad Note: timestamps may be slightly misaligned on podcast apps (but not on YouTube) due to dynamic ads.

Dr. Jordan B. Peterson speaks with the CEO of QOL Medical, Derick Cooper. They discuss how immunological systems confront pathogens and store information, the trait most associated with entrepreneurial success, the complicated patterns of behavior that scale from cellular interaction to metaphysics, and how a spirit of reciprocity can be utilized to uplift the individual as well as the community, society, and upward. Derick Cooper is the Chief Executive Officer of QOL Medical, LLC, a large, private specialty biopharmaceutical company that makes drugs and biologics for rare diseases. QOL is a commercial stage company founded in 2003 with fully integrated capabilities ranging from sales and marketing to drug development to bioprocess-based manufacturing. Prior to 2010, Cooper spent 16 years in investment banking, mergers and acquisitions, venture capital, corporate finance, and operations with The Robinson-Humphrey Company in Atlanta, as a portfolio manager with Sirrom Capital, formerly the largest mezzanine lender in the US, and with CooperSmith, formerly the largest independent baked foods company in the US. - Links - 2024 tour details can be found here https://jordanbpeterson.com/events   Peterson Academy https://petersonacademy.com/ For Derick Cooper: On X https://twitter.com/derick_cooper5 QOL Medical website www.qolmed.com