The Itch: Allergies, Asthma & Immunology

Independence, risk-taking, and peer pressure. Welcome to the teenage years with food allergies! Managing food allergies during the teen years poses new challenges. Tweens and teens are gaining independence, navigating social pressures, and taking more responsibility for their health. But this is also the stage where risky behavior peaks, and the risk for severe allergic reactions is highest. That's why clear communication and trust matter more than ever. In this episode of our Food Allergy Stages Series, Dr. Travis Miller joins Kortney and Dr. Payel Gupta to unpack how food allergy management changes from ages 12 to 18. We talk about empowering teens through shared decision-making, building trust between parents and teens, and developing essential life skills like label reading, restaurant communication, and self-advocacy. We also dive into difficult topics like bullying, alcohol, and mental health. Finally, we address why emotional support is just as important as carrying an epinephrine auto-injector. What we cover in our episode about managing food allergies in teens: Why trust matters. Teens are more likely to follow allergy routines when they feel heard and involved. Empowering independence. From grocery shopping to reading labels, this is the age to start turning over the reins. Talking about risky behavior. Alcohol and dating can put teens with food allergies at higher risk. Bullying and boundaries. Learn how to spot signs of bullying and who can help your teen feel safe and supported. Mental health and identity. Food allergies can affect confidence. We share ways to support emotional wellness and self-esteem. Episode 5 in our “Food Allergies: Ages & Stages” series  Across six episodes, we explore how food allergies show up and shift through different phases of life, from introducing solids in infancy to navigating school and adapting in adulthood. We're here with evidence-based info, expert insights, and lived experience to guide you through it all. Episode 110: Early Allergen Introduction Episode 111: Food Allergy Basics for Newly Diagnosed Families Episode 112: Managing Food Allergies in Babies and Toddlers Episode 113: Managing Food Allergies in School-Age Children Thanks to Genentech and Aquestive for sponsoring this episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

How do you help your child go from knowing they have a food allergy to actually managing it in everyday life? This is the stage when everything starts to shift. Between the ages of 5 and 11, your child is learning how to describe symptoms, speak up at school, and navigate birthday parties. They're also watching you closely and picking up how to talk about food allergies based on how you do it. In this episode of our Food Allergy Stages & Stages Series, pediatric allergist and immunologist Dr. Dave Stukus joins Kortney and Dr. Payel Gupta to talk about how food allergy care changes in the early school years.  What we cover in our episode about managing food allergies in ages 5 to 11: Build awareness early. Teach kids to name their allergens, recognize symptoms, and use simple words to describe how they feel. Model safe behavior. Kids learn by watching you read labels, ask questions, and stay calm. Normalize epinephrine. Practice with a trainer and talk about it openly so it feels familiar, not scary. Prepare for real-life situations. From school to parties, give kids scripts and strategies to feel confident and included. Support emotional wellness. Watch for signs of anxiety and help your child feel empowered, not afraid. Episode 4 in our “Food Allergies: Ages & Stages” series  Across six episodes, we explore how food allergies show up and shift through different phases of life, from introducing solids in infancy to navigating school and adapting in adulthood. We're here with evidence-based info, expert insights, and lived experience to guide you through it all. Episode 1: Early Allergen Introduction (Ep. 110) Episode 2: Food Allergy Basics for Newly Diagnosed Families (Ep. 111) Episode 3: Managing Food Allergies in Babies and Toddlers (Ep. 112) Made in partnership with the Allergy & Asthma Network. Thanks to Genentech and Aqestive for sponsoring today's episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.   Timestamps 01:42 Breaking down food allergy care by age group 02:58 What kids need to know about living with food allergies 04:47 Sharing allergy information without creating fear 06:40 Talking to children about symptoms 08:40 What to tell kids about epinephrine 11:04 Helping kids without passing on fear or anxiety 13:18 Mental health signs related to food allergies 16:04 Managing allergens in the home environment 19:50 The pros and cons of allergy tables at school 21:42 Communicating with schools and daycares 25:29 Preparing for parties and sleepovers 27:33 Final tips for parenting kids with food allergies (ages 5–11)

How do you keep a baby or toddler safe with food allergies when they put everything in their mouths and can't yet explain how they feel? This stage of life is full of firsts, not just for your child, but for you as a parent managing food allergies. From introducing new foods to navigating daycare and watching for reactions in a child who can't speak yet, there are countless moments you'll need to manage. This episode focuses on building safe habits early, empowering caregivers, and showing how simple routines (like label reading or toy wiping) can make a big difference. Allergist Dr. Basil Kahwash joins Kortney and Dr. Payel Gupta to explore how food allergy care evolves from infancy through preschool. They cover real-life, practical strategies from wiping toys and watching for symptoms to managing daycare risks and building early self-advocacy skills. What we cover in our episode about managing food allergies in toddlers: Why age matters. Babies, toddlers, and preschoolers each need different safety strategies. What symptoms look like. Learn how reactions can show up in babies who can't talk. Introducing new foods. Why early introduction still matters even after a new food allergy diagnosis. Daycare safety tips. How to prep caregivers and keep your child protected. Building habits early. From label reading to toy wiping, young kids learn by watching you. Episode 3 in our “Food Allergies: Ages & Stages” series  Across six episodes, we explore how food allergies show up and shift through different phases of life, from introducing solids in infancy to navigating school and adapting in adulthood. We're here with evidence-based info, expert insights, and lived experience to guide you through it all. Episode 1: Early Allergen Introduction (Ep. 110) Episode 2: Food Allergy Basics for Newly Diagnosed Families (Ep. 111) Episodes to build a better food allergy foundation: Episode 59: What is Anaphylaxis and When to Use Epinephrine Episode 95: The Science Behind Allergic Reactions Episode. 97: The Nuances of Food Allergy Testing  Episode 98: Food Allergy Treatment and Management   Made in partnership with The Allergy & Asthma Network. Thanks to Genentech and Acuqestive for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Just diagnosed with a food allergy and feeling lost? You're not alone and don't have to figure out food allergy life by yourself. We're here to help you understand food allergy basics: what causes allergic reactions, how to recognize symptoms, and how to manage your allergy safely, every day. This is the second episode in our Food Allergies: Ages & Stages, and it's all about building a strong foundation after a new diagnosis. Whether it's your child, your partner, or you who was recently diagnosed, Kortney and Dr. Payel Gupta walk through everything you need to know in those early days. From understanding how allergic reactions work to learning about life-saving tools like epinephrine, and new management options like OIT and omalizumab. Dr. G explains what causes your immune system to misfire, how fast symptoms can appear, and why no two reactions are the same. We also dive into real-life strategies like carrying your epinephrine device, knowing when and how to use it, and navigating social situations. Plus, Kortney shares personal tips that have helped her live safely with food allergies for over 30 years. What we cover in our episode about managing a new food allergy diagnosis What just happened?! We explain what causes allergic reactions, including the roles of IgE, histamine, and mast cells. Are all allergic reactions the same? Learn how quickly reactions can occur and why symptoms aren't always predictable. Why is epinephrine so important? When to use epinephrine, how to use it, and why antihistamines aren't enough. New options to help manage food allergies. A look at treatments like OIT and omalizumab (Xolair) and why you still need to carry your epi. Peace of mind with an action plan. What to include in a Food Allergy Action Plan and how to help others take your allergy seriously. Episode 2 in our “Food Allergies: Ages & Stages” series  Across six episodes, we explore how food allergies show up and shift through different phases of life, from introducing solids in infancy to navigating school and adapting in adulthood. We're here with evidence-based info, expert insights, and lived experience to guide you through it all. Episodes mentioned to help build your foundation: Episode 59: What is Anaphylaxis and When to Use Epinephrine Episode 95: The Science Behind Allergic Reactions Episode 98: Food Allergy Treatment and Management Ep. 110: Early Introduction of Allergenic Foods – Preventing Food Allergies Before They Start Made in partnership with The Allergy & Asthma Network. Thanks to Genentech and Acuqestive for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Did you know you could potentially reduce your baby's risk of developing food allergies by up to 80%? That's the power of early allergen introduction. Feeding a baby the top 9 allergens consistently starting between 4 to 6 months can make a life-changing difference. We're launching a brand-new series about food allergies at various stages of life. Whether you're just starting solids, navigating a new diagnosis, or in a new stage of life, this series is here to support you with evidence-based tips and real talk. In this first episode, Kortney and Dr. Payel Gupta explore how to potentially prevent food allergies before they even develop. Why do you want to know more about introducing allergens to baby? For years, parents were told to wait until toddlers were older before introducing allergenic foods. But groundbreaking research, including the LEAP, LEAP-On, and PETIT studies, turned that advice on its head.   We no longer wait to feed babies food allergens. Instead, early (around 4–6 months) and sustained exposure to top allergens like peanut and egg is recommended for all babies. In this episode, Dr. G and Kortney explain the studies, walk you through how to do it safely, and bust common myths that leave parents confused or anxious. What we cover in our episode about early allergen introduction Why guidelines changed: Learn how the LEAP & PETIT studies reshaped allergy prevention. How to introduce the top 9 allergenic foods safely, including forms that are appropriate for infants. What “sustained exposure” means and how often to serve allergens after that first taste. How eczema increases allergy risk and what transcutaneous sensitization means. What allergic signs to watch for: mild hives vs. serious allergic reactions and when to call the doctor. More resources about food allergy prevention USDA Updates Dietary Guidelines to Include Introduction of Food Allergens Delaware Adopts Law Covering Early Introduction of Food Allergens What is a food allergy? American Academy of Pediatrics Early Feeding Guidelines AAAAI / ACAAI handouts on introducing peanut & egg FARE: How to Use Peanut Puffs Safely Solid Starts: Peanut Butter Guide (Creative Ways to Serve) PreventAllergies.org Recipe Library Our infant anaphylaxis episode (with Dr. Mike)

Have you wondered why having more drug options matters for chronic rhinosinusitis with nasal polyps? In the inaugural episode of our new series, The Itch Review, co-hosts Kortney and Dr. Payel Gupta, along with special guest Dr. Michael Blaiss, unpack the journal article "Tezepelumab in Adults with Severe Chronic Rhinosinusitis with Nasal Polyps," published in the New England Journal of Medicine on March 1, 2025. This article is about the Phase III WAYPOINT trial of tezepelumab. Already approved for severe asthma, this once-monthly biologic is now showing promise in chronic rhinosinusitis with nasal polyps (CRSwNP). Over 52 weeks, 408 patients were randomized to receive 210 mg of tezepelumab every four weeks or placebo. Researchers tracked nasal-polyp scores, congestion, sense of smell, and rates of rescue surgery. In this episode, we provide a brief overview of what CRSwNP is, why inflammation drives polyp formation and how blocking TSLP fits into today's biologics options. We'll walk you through the WAYPOINT Phase III design, explain the primary and secondary endpoints, and translate the headline results into what they mean for real-world patients who've exhausted their treatment options. ➡️ Get the infographic here. What we cover in our episode about treating chronic rhinosinusitis with nasal polyps with tezepelumab CRSwNP basics & tezepelumab mechanism of action: How nasal polyps form and why targeting TSLP can reduce inflammation WAYPOINT design: 52-week, placebo-controlled Phase III study in 408 patients  Primary endpoints: Mean change in nasal polyp score and nasal-congestion score Secondary endpoints: Smell recovery, need for rescue surgery or systemic steroids, and quality-of-life measures Why choice matters: Every CRSwNP patient responds differently, and having more treatment options means more chances to find the right fit   Made in partnership with The Allergy & Asthma Network. Thanks to AstraZeneca for sponsoring today's episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Ever wonder who's working behind the scenes to improve allergy care nationwide? In this episode, we sit down with Dr. James Tracy, the 2024-2025 president of the American College of Allergy, Asthma & Immunology (ACAAI), to explore how the College supports both patients and clinicians. Dr. Tracy shares how he got involved, what drives his leadership, and what's ahead for the future of allergy and asthma care. From workforce shortages to the promise of AI in medicine, this conversation takes you behind the curtain of the specialty. Plus, we dig into how patients and providers alike can make a difference through advocacy. What we cover in our episode about ACAAI, leadership & allergy care Dr. Tracy's unique path to leadership: How his non-traditional journey from practicing in rural Nebraska to leading the ACAAI shaped his approach to advocacy and patient care. Creating leadership opportunities: Why mentorship and involvement in ACAAI committees can open doors for clinicians, fellows-in-training, and future leaders in allergy and immunology. Patient tools that make a difference: Free ACAAI resources that help patients better understand and manage their conditions. The evolving role of the allergist: How allergists are uniquely trained to manage complex conditions and why that matters as technology, treatment options, and care delivery evolve. Future-focused leadership at ACAAI: Dr. Tracy's vision for tackling workforce shortages, embracing AI and gene editing, and keeping patient care at the center of innovation. Resources: Asthma Allergy Day on Capitol Hill More information about advocacy The American College of Allergy Asthma and Immunology Patient Resources The American College of Allergy Asthma and Immunology Allergist Finder

Ever wonder how culture and language barriers affect diagnosing chronic spontaneous urticaria (CSU) in Latinx patients? In this episode, allergist Dr. Juanita Mora joins Kortney and Dr. Gupta to discuss chronic spontaneous urticaria (hives) and the unique challenges faced by the Latinx community. They highlight the importance of cultural competency in health care and the barriers that Latinx patients often encounter, such as language differences and access to specialists. They also discuss how Latinx patients are often not given all treatment options for hives, such as biologics.  Dr. Mora emphasizes the importance of having resources available in Spanish and encourages patients and families to advocate for their care. They explore practical tips on how technology, family support, and proper patient education can help overcome barriers, leading to better diagnosis, treatment, and improved quality of life for Hispanic patients managing CSU. What we cover in our episode about chronic hives in the Latinx community: Diagnosing hives in skin of color: How CSU symptoms can present differently on darker skin tones, making accurate diagnosis harder.  Overcoming barriers for Latinx patients: The specific hurdles the Latinx community faces like language barriers, limited access to Spanish-speaking allergists, and challenges obtaining advanced treatments such as biologics. Role of family and community support: How involving family members and community leaders can improve CSU awareness, reduce stigma, and encourage patients to seek timely medical treatment. Importance of Spanish-language patient education: Why accessible, culturally relevant education and resources in Spanish are essential for empowering Latinx patients to manage their CSU effectively. Cultural beliefs and CSU diagnosis: How cultural perceptions around health and family influence the timing of diagnosis and willingness to seek medical care. Resources Spanish ¿Qué es la urticaria crónica? Urticaria Crónica - Dr. Antonio Olvera  Urticaria crónica espontánea/idiopática (erupción crónica) Protocolo urticaria cronica  Resources English Chronic Urticaria Management, Resources & Glossary of Terms Chronic Hives: 10 Actions to Support Your Mental Health Why Are My Hives Not Going Away? Made in partnership with The Allergy & Asthma Network. Thanks to Novartis for sponsoring today's episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Have you ever wondered if steroids are the best choice for managing your eczema?  While both topical and oral steroids offer quick relief from severe eczema flares, understanding their long-term risks and safer alternatives can dramatically improve your quality of life. In this episode, Dr. Mondana Ghias joins Kortney and Dr. Gupta to discuss the complex role of systemic corticosteroids in eczema management. They dive deep into the short-term relief that steroids provide for severe eczema symptoms and emphasize why steroids must be approached cautiously due to potential side effects and dependency risks. Dr. Ghias also highlights the unique challenges of eczema care for individuals with skin of color, addressing differences in treatment response and the common issue of hypopigmentation caused by topical steroids. What we cover in our episode about steroid use in eczema treatment: Role of Systemic Steroids: When steroids are necessary and how they quickly manage severe eczema flares. Risks and Side Effects: Understanding the serious long-term effects of systemic and topical steroids. Steroid Withdrawal: Recognizing the signs of steroid withdrawal and strategies to manage rebound effects. Challenges of Topical Steroids for Skin of Color: The unique risks of steroid use and managing hypopigmentation. Alternatives to Steroids and Innovative Treatments: The rise of biologics and targeted therapies offering safer, long-term solutions. The Importance of Specialist Care: Working with a dermatologist or allergist will help you find a sustainable long-term management plan. Made in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today's episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Ever wonder if the “asthma shot” from the ER, or those go-to steroid pills for your asthma flares, might be doing more harm than good? Dr. Dipa Sheth joins us to discuss the common pitfalls of relying too heavily on oral corticosteroids (OCS), also known as oral steroids. We unpack why these systemic medications should generally be reserved for short-term use. She also shares how improving asthma control can help you avoid frequent steroid use in the first place. Although oral steroids can effectively treat asthma flare-ups in emergency settings, overuse poses significant risks, from adrenal insufficiency to osteoporosis. We dig into ways patients can proactively manage their asthma, reduce ER visits, and talk to healthcare providers about preventive treatments (like inhalers or biologics for asthma) that keep inflammation in check without the side effects of frequent steroid use. Note: Although we discuss oral corticoid steroids, they can also be given as injections or via IV drip for asthma. We would also like to refer to them as systemic steroids as they impact the entire body, unlike inhaled steroids, which target the airways and lungs.  What we cover in our episode about oral steroid overuse Understanding Oral Corticosteroids (OCS): Learn what these steroids (often called the “asthma shot” in the ER) are and how they can help with severe flare-ups. Why Overusing Steroids Can Be Risky: Discover the potential long-term side effects of relying on systemic steroids (pills, injections, or IV), from adrenal insufficiency and osteoporosis to more frequent infections. Short-Term Fix vs. Lasting Relief for Asthma Care: Learn how urgent care or ER visits may mask an under-managed condition and why seeing a specialist can improve asthma control. Safer Alternatives to OCS: Explore inhaled corticosteroids, biologics, and other preventive treatments that target asthma at its source, reducing the need for frequent steroids. Taking Control and Reducing ER Visits: Get practical strategies for working with your healthcare provider to minimize steroid use, prevent flare-ups, and break free from the cycle of repeated steroid courses. This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today's episode. This podcast is for informational purposes only and does not substitute for professional medical advice. If you have any medical concerns, always consult with your healthcare provider.

What does "control" mean when managing allergic conditions, and how can you achieve it? When you have asthma, eczema, nasal polyps, or other conditions caused by type 2 inflammation, reaching a state of control can dramatically improve your quality of life. But what does "control" really mean? Is it the same as a cure? And what steps should you take if your current treatment isn't working? In this episode, Dr. Payel Gupta and Kortney dive deep into the idea of control in the context of Type 2 inflammation. They explain that control doesn't mean you'll never experience symptoms again. Rather, it's about having fewer, milder flare-ups and the freedom to live your life more comfortably. Dr. Gupta explains what control means for various conditions, why it matters, and how recognizing signs of poor control can protect against long-term complications. Kortney shares her own experience managing asthma and eczema with biologics, highlighting why symptom tracking and regular check-ins with your doctor are essential, even when you're feeling good. What we cover in our episode about achieving control over Type 2 inflammation: Defining Control in Type 2 Inflammation: Learn what control actually looks like. Discover the difference between controlling symptoms and curing the condition entirely. Why Achieving Control Matters: Find out why uncontrolled Type 2 inflammation can lead to worsening symptoms, frequent hospital visits, increased medication needs, and significantly impact your day-to-day life. Managing Multiple Conditions and the Role of Specialists: Understand why having more than one Type 2 inflammatory condition can lead to a "domino effect," worsening overall health. Learn how specialists like allergists can help you manage multiple conditions effectively. Treatment Options for Controlling Type 2 Inflammation: Get an overview of available treatments, including biologic therapies specifically designed to target underlying inflammation pathways. Understand the role these medications play in improving quality of life. Practical Tips for Managing Symptoms at Home: Learn ways to reduce inflammation by identifying and minimizing triggers, allergy-proofing your environment, and adopting healthier lifestyle practices. More episodes that will help you:  Ep. 101 What is Type 2 Inflammation Ep. 98 Food Allergy Treatment and Management Ep. 87 What biologic therapies are available for allergic conditions? Ep. 85 Navigating Biologic Therapy – What You Need to Know Ep. 78 Chronic Spontaneous Urticaria Treatments Ep. 56 Biologic Therapies for Asthma Made in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today's episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Can you slow down the atopic march and prevent kids from developing more allergic diseases? Type 2 inflammation plays a central role in allergic diseases, which impact children from infancy through adulthood. From eczema and asthma to food allergies and allergic rhinitis, these conditions are all connected through an underlying immune response: Type 2 inflammation. But is there a way to prevent the progression of these diseases? In this episode, Dr. Payel Gupta and Kortney are joined by Dr. Priya Bansal to explore how Type 2 inflammation manifests in children, the concept of the atopic march, and whether treatments like immunotherapy or biologics can alter the course of the diseases. Many parents aren't aware of the atopic march until their child starts developing multiple allergic conditions. Understanding how Type 2 inflammation progresses and when to intervene can be crucial in managing these diseases early. Dr. Bansal shares her expert insights on the best time to seek treatment and how biologics may help some children break the cycle of inflammation. What we cover in our episode about type 2 inflammation in children Understanding Type 2 Inflammation in Children: Understand type 2 inflammation's role in conditions like eczema, asthma, allergic rhinitis, and food allergies. Learn why children with one allergic condition often develop others over time. The Atopic March: Discover why some children with eczema go on to develop asthma and food allergies. Learn why early intervention can make a difference. Immunotherapy and Biologics: Can They Change the Course of Disease? Understand how allergy shots, OIT, SLIT and biologics work, when they are recommended, and whether they can stop or slow down the atopic march in children. When to See an Allergist & Parental Concerns About Treatment: Learn the signs that indicate your child may need an allergist evaluation. Plus, we address common concerns about aggressive treatment options, including steroids and biologics. Managing Type 2 Conditions at Home & School: Practical tips for parents navigating food allergic diseases. Made in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today's episode. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.  

Why do conditions like asthma, nasal polyps, or eczema become more severe when they coexist? Kortney and Dr. Payel Gupta are joined by Dr. Michael Blaiss to explore the common thread linking multiple allergic and inflammatory diseases: Type 2 Inflammation. If you've ever wondered why certain conditions often appear together, this deep dive will help you connect the dots. Type 2 Inflammation is a hot topic in immunology because it's the engine that drives many allergic and inflammatory diseases. It's also the key to modern treatment strategies, including targeted biologic therapies. Dr. Blaiss explains how clinicians recognize multiple Type 2-driven conditions in the same patient, why it is important to know the connection between multiple conditions and Type 2 inflammation, and the big-picture benefits of treating inflammation aggressively to prevent complications. What We Cover in our Episode about The Diseases Related to Type 2 Inflammation Conditions Related to Type 2 Inflammation: Explore how chronic rhinosinusitis with nasal polyps (CRSwNP), rhinitis, asthma, atopic dermatitis (eczema), prurigo nodularis, eosinophilic esophagitis (EoE), and food allergies can all share a common inflammatory pathway. The Likelihood of Having Multiple Type 2 Conditions: How often do patients have more than one condition related to Type 2 Inflammation, and why is recognizing overlap a potential game-changer for diagnosis and treatment? Treating the Root Inflammation vs. Individual Symptoms: Discover how clinicians decide whether to address each condition separately or tackle the underlying Type 2 inflammatory process affecting them all. Markers & Personalized Medicine: Dr. Blaiss discusses whether potential tests, such as eosinophil counts or IgE levels, can confirm Type 2 inflammation. He also explains how knowing you have Type 2 Inflammation can help guide targeted therapy. Prevention & Aggressive Intervention: Understand why it's crucial to treat inflammation early to reduce the risk of developing multiple Type 2 conditions and how this proactive approach benefits long-term health. Want to know more? Type 2 Inflammation Overview – Explains the role of Type 2 inflammation in conditions like asthma and nasal polyps. This podcast is for informational purposes only and does not substitute for professional medical advice. If you have any medical concerns, always consult with your healthcare provider. Produced in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

What do asthma, eczema, EoE, and nasal polyps have in common? They all stem from Type 2 inflammation! Type 2 inflammation is a major cause of many allergic and inflammatory conditions, yet it remains widely misunderstood. In this first episode of our four-part series on Type 2 Inflammation, we discuss the basics, unpack its impact on the immune system, explain how it contributes to chronic inflammation in the body, and explain why it matters for treatment and management. What we cover in our episode about Type 2 Inflammation Understanding Inflammation: Inflammation is your body's natural defence mechanism, but it can become problematic when it turns chronic. Normal vs. Chronic Inflammation: Not all inflammation is bad! Learn the difference between the body's normal immune response and long-term chronic inflammation. What Sets Type 2 Inflammation Apart? Unlike other immune responses, Type 2 inflammation involves a specific pathway. Key Players in Type 2 Inflammation: Th2 cells, cytokines (IL-4, IL-5, IL-13), IgE antibodies, and eosinophils. Measuring Type 2 Inflammation: How blood tests can help determine if Type 2 inflammation is contributing to your symptoms. Want to know more? Type 2 Inflammation Overview – Explains the role of Type 2 inflammation in conditions like asthma and nasal polyps. This podcast is for informational purposes only and does not substitute for professional medical advice. If you have any medical concerns, always consult with your healthcare provider. Produced in partnership with The Allergy & Asthma Network. Thanks to Sanofi for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.  

We're celebrating 100 episodes and six years of The Itch Podcast!  In this special episode, Dr. Payel Gupta and Kortney reflect on their journey—sharing insights from their experiences as a doctor-patient duo. Dr. G talks about how the podcast has influenced her as a provider, while Kortney shares how it has literally changed her life. We also introduce The Journal Club, a brand-new series in which we unpack the latest journal articles in our famous, easy-to-digest style. What We Cover in This Episode: Why Kortney decided to share her story about allergies, asthma, and eczema. Why Dr. Gupta became an allergist and how her personal journey shaped her career. The impact of patient advocacy—why Dr. G is passionate about empowering patients. The Itch Podcast's partnership with Allergy & Asthma Network and how it's raising awareness and education. Lessons from six years of podcasting—what we've learned from our guests, experts, and YOU, our listeners. Introducing The Journal Club—a new series unpacking medical research in a simple and relatable way.

What would you do if your baby had a severe allergic reaction? Recognizing and treating anaphylaxis in babies can be overwhelming, but knowing the right signs and symptoms can help you decide when to use epinephrine or distinguish it from a cold. Pediatric allergist Dr. Michael Pistiner joins us to discuss how to recognize anaphylaxis in infants, when to use epinephrine, and why early food introduction matters. Understanding food allergies in infants, anaphylaxis symptoms, and emergency treatment is essential for parents and caregivers to act quickly and confidently. This episode will give you the confidence to respond in an emergency. What We Cover in Our Episode on Infant Anaphylaxis What is anaphylaxis, and how does it present differently in infants vs. older children? How to differentiate an allergic reaction from common childhood illnesses. Why early allergen introduction is crucial and How over-testing can lead to unnecessary worry. When to use epinephrine vs. antihistamines for treating reactions. Parental fears about epinephrine and why it's always the safest choice in an emergency. When to call 911 after administering epinephrine. Why carrying two epinephrine auto-injectors is essential for managing severe reactions. More resources about infant anaphylaxis:  More from Dr. Pistiner about infant anaphylaxis What is Epinephrine More About Food Allergies More About Anaphylaxis Food Allergy Treatment & Management Living with Food Allergies Guide What Can You Do If You Can't Afford Allergen-Free Foods? What if I Can't Afford My Allergy Medications? Early Introduction Guidelines This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Kaleo for sponsoring today's episode.  This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Is there a cure for food allergies? Unfortunately, not yet. However, exciting new treatments are emerging that offer hope and improved quality of life for those managing food allergies. Dr. Maya N. Gharfeh joins us to explore innovative options for treating food allergies. In this episode, we cover comprehensive strategies ranging from traditional avoidance techniques to cutting-edge treatments like omalizumab (Xolair) and Oral Immunotherapy (OIT). While these treatments are promising, they are not cures. Dr. Gharfeh shares valuable insights on integrating these options into your allergy management plan. She also discusses how to determine whether Xolair or OIT might be the right choice for you or your child. Despite advancements, avoidance remains the cornerstone of food allergy management and must still be practiced even while undergoing treatment. What We Cover in the Episode about Food Allergy Treatment Options Effective methods for food allergy avoidance Deciphering packaged food labels and "may contain" statements Understanding cross-contamination and cross-contact Insights into Xolair and its role in food allergy treatment An overview of Oral Immunotherapy (OIT) Guidance on choosing between Xolair and OIT GUIDE: Food Allergen Alternative Names on Labels Produced in partnership with The Allergy & Asthma Network. Thanks to Genetech for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Think diagnosing food allergies is as simple as running a test? Think again. Food allergy testing is a maze of gray areas, false positives, and, hopefully, a clear food allergy diagnosis. Navigating food allergy testing can feel overwhelming, with skin pricks, blood tests, and conflicting advice. How do you determine which tests are truly useful? How can you avoid unnecessary dietary restrictions from false results? In this episode, Dr. David Stukus, a board-certified allergist and immunologist, joins Dr. Gupta and Kortney to demystify the science of food allergy testing. From the importance of patient history to the latest diagnostic tools, Dr. Stukus provides clear guidance to help you make informed decisions while navigating food allergy testing. What we cover in our episode about food allergy testing The Crucial Role of History in Food Allergy Diagnosis: Dr. Stukus highlights why understanding a patient's reaction history (symptoms, timing, and context) is critical for guiding effective testing decisions. Choosing the Right Tests: We break down skin prick testing, blood tests like IgE and component testing, and innovations like epitope mapping. Dr. Stukus explains why IgG testing is untrustworthy and emphasizes oral food challenges as the gold standard for diagnosis. False Positives and Negatives: Learn why expert interpretation of test results is crucial and how overtesting can lead to unnecessary restrictions and confusion. When to See an Allergist: Practical advice on when to consult a specialist and what to expect during your visit for evidence-based care. This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Genentech for sponsoring today's episode. About Our Guest Dr. David R. Stukus is a renowned allergist and immunologist at Nationwide Children's Hospital and a professor at Ohio State University College of Medicine. He is known for his dedication to patient education and myth-busting in allergy care and is a trusted expert in food, asthma, and environmental allergies. Follow Dr. Stukus on Instagram: @allergykidsdoc

Can a TikTok video from a doctor change how we understand health? Have you ever scrolled through social media and found a doctor busting medical myths or sharing health advice? Platforms like Instagram and TikTok are transforming how we access health information and interact with medical professionals. Dr. Zachary Rubin joins Dr. Gupta and Kortney to explore the evolving role of doctors on social media. From creating trustworthy content to balancing the risks and rewards of being a medical professional online, Dr. Rubin shares his journey and tips for using social platforms to educate and empower. Whether you're a patient seeking reliable health information or a healthcare professional curious about sharing expertise, this episode dives deep into the intersection of social media and medicine. What We Cover in Our Episode About Doctors on Social Media Why Social Media Matters for Doctors: Dr. Rubin explains why having a presence online is vital for normalizing conditions like food allergies and providing access to reliable health education. Navigating Risks and Rewards: Learn how doctors manage the challenges of creating content while maintaining professionalism and protecting themselves online. Fighting Misinformation: We discuss how to responsibly call out misinformation and share accurate information to build trust. Bridging Healthcare Gaps: Discover how platforms like Instagram and TikTok help patients without access to specialists find trustworthy medical advice. Tips for Creating Reliable Medical Content: Dr. Rubin shares strategies for crafting engaging, accurate posts and curating a social media feed filled with credible health information. Follow Dr. Rubin on Social Media: Instagram:@rubin_allergy YouTube: @rubin_allergy TikTok: @rubin_allergy Twitter: @rubin_allergy

Have you ever wondered what happens inside your body during an allergic reaction? From itchy eyes to anaphylaxis, the science behind allergies explains why some reactions are mild while others can be life-threatening. In this episode, we break it all down. Dr. Payel Gupta and Kortney unpack the basics of food allergies, starting with what IgE antibodies are and how they play a role in allergic reactions. They explain what happens when your immune system encounters an allergen, breaking it down with our favorite pinata analogy. This deep dive into the immune system reveals why reactions can range from mild to life-threatening and explores the differences between food allergies, intolerances, and oral allergy syndrome. If you're newly diagnosed or curious about the science behind allergies, this episode offers valuable insights to help you understand your body and stay safe. What we cover in our episode about what happens in an allergic reaction What is an allergic reaction? Discover how your immune system identifies allergens and triggers a response involving IgE antibodies, mast cells, and histamine. Confused? We use our pinata analogy to simplify it. The role of histamine and inflammation. Learn how histamine is released during an allergic reaction, leading to inflammation and common symptoms. Understanding food allergies vs. food intolerances. Explore the key differences, including symptoms, risks, and why terminology matters. Oral allergy syndrome and environmental allergies. Understand why some allergies don't lead to anaphylaxis and how cross-reactivity can cause symptoms. Anaphylaxis and severe reactions. Explore why some reactions are life-threatening and how factors like exposure levels and health conditions can influence severity. More resources about allergies:  A Complete Guide to Allergies More About Food Allergies More About Anaphylaxis Food Allergy Treatment & Management Living with food allergies guide What Can You Do If You Can't Afford Allergen-Free Foods? What if I Can't Afford My Allergy Medications? This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Genetech for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

Exploring Neffy Nasal Spray: A Needle-Free Epinephrine Option Managing anaphylaxis just became easier with Neffy, the FDA-approved nasal spray for epinephrine. This innovative, needle-free option is transforming emergency allergy care. Dr. Autumn Burnette joins Dr. Payel Gupta and Kortney to discuss how Neffy works, who it's best suited for, and its potential impact on anaphylaxis treatment. With her expertise in allergy and immunology, Dr. Burnette addresses common concerns about Neffy's effectiveness, highlights its benefits, and shares practical details like cost, shelf life, and heat sensitivity. What We Cover in our Episode About Neffy Nasal Spray Delivery System A Game-Changer for Anaphylaxis: Discover how Neffy offers a needle-free option for delivering life-saving epinephrine during severe allergic reactions. Patient Benefits of Neffy: Learn how its ease of use and accessibility can make anaphylaxis management less daunting for patients. Addressing Skepticism About Neffy: Dr. Burnette explains how studies validate Neffy's effectiveness and addresses questions about trusting a nasal spray for emergencies. Practical Tips for Neffy Use: Get insights on cost, insurance coverage, shelf life, and whether Neffy works with nasal congestion or nose jobs! Expanding Treatment Options: Explore why having more options like Neffy is exciting for patients and healthcare providers alike. More resources about Anaphylaxis and Neffy:  Neffy: https://www.neffy.com/ Anaphylaxis: https://allergyasthmanetwork.org/anaphylaxis/ Epinephrine: https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ Made in partnership with The Allergy & Asthma Network. Thanks to ARS Pharma for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement. This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.  

Curious About Neffy, the New Nasal Epinephrine Spray? We're diving into everything you need to know about Neffy, the new FDA-approved nasal spray for epinephrine. This groundbreaking, needle-free option provides an easy way to manage anaphylaxis in emergencies. Dr. Sakina Bajowala joins Dr. Gupta and Kortney to explore Neffy's unique nasal delivery system, what distinguishes it from traditional auto-injectors, and the science behind its development. With her expertise in allergy and asthma care, Dr. Bajowala walks us through Neffy's FDA approval journey, the technology that powers the nasal spray, and how it's changing the landscape of allergy treatment. What We Cover in Our Episode on Neffy Nasal Spray: Why Neffy Nasal Spray is Unique: Dr. Bajowala explains why nasal epinephrine is an innovative choice for anaphylaxis treatment and when it may be preferable to injectables. FDA Approval for Neffy: We discuss the rigorous testing behind Neffy's FDA approval, including studies conducted with actual patients post-approval. Intravail Technology in Neffy Nasal Spray: Learn about the advanced technology enabling rapid, effective absorption through the nasal passages for timely intervention. Considerations for Using Neffy Nasal Spray: We explore practical aspects of Neffy's use, from nasal congestion to potential side effects. Neffy Dosing and Side Effects: Dr. Bajowala provides insights on dosing, including when a second dose may be recommended. Helpful links: Neffy: https://www.neffy.com/ Anaphylaxis: https://allergyasthmanetwork.org/anaphylaxis/ Epinephrine: https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ This podcast is made in partnership with The Allergy & Asthma Network. Thanks to ARS Pharma for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

It's that time of year again—open enrollment is here! Don't worry, we're here to help you choose the best health insurance for you and your family. Lacey Varnon from the National Association of Medication Access and Patient Advocacy (NAMAPA) is back with Dr. Gupta and Kortney to discuss everything you need to consider when selecting a health insurance plan. This episode is all about understanding health insurance during open enrollment, from picking the right type of plan to ensuring your coverage fits your specific needs. We cover essential aspects of open enrollment health insurance, including networks, premiums, copayments, and long-term medication coverage, so you can feel confident you're choosing a plan that works for you. What We Cover in Our Episode on Open Enrollment Health Insurance: Key Factors to Consider: Lacey explains the importance of listing your doctors, diagnoses, and medications to ensure they're covered. Understanding Premiums, Deductibles, and Networks: Gain insight into how these elements impact your out-of-pocket costs and access to care. Plan Types – HMO, PPO, EPO, and POS: We break down each type of plan, including pros and cons, to help you decide which suits your healthcare needs. Special Considerations for Pharmacy Benefits and Long-Term Medications: Lacey offers advice on accessing necessary medications through your health plan or alternative methods if they are not covered. Navigating Open Enrollment with Family Needs in Mind: Tips on choosing a plan that considers your family member's medical needs and how you've used insurance in the past. More resources about health insurance:  Health Insurance Coverage in the United States Why was my prescription denied by insurance? Health Insurance for Asthma and Allergies Choosing the Right Health Insurance Plan Navigating Insurance Denials and Filing Appeals NAMAPA: National Association for Medication Access and Patient Advocacy Medication Access Network This episode is made in partnership with the Allergy & Asthma Network and in collaboration the National Association of Medication Access and Patient Advocacy (NAMAPA). We thank Amgen for sponsoring this episode. 

Discover Meka's journey with chronic hives in skin of color—a powerful story of resilience, self-advocacy, and building the right support system to get the care she deserves. Emmeka, or "Meka," joins Dr. Gupta and Kortney to share her personal experience of living with chronic urticaria as a person with skin of color. Meka describes her journey from a lack of resources addressing hives on black skin to finding effective support and resources. She opens up about the long path to her diagnosis, the depth of her online research into chronic spontaneous urticaria (CSU), and the importance of finding knowledgeable, empathetic healthcare providers. Meka's optimism highlights how a proactive approach, a trusted care team, and a strong support network can make a difference in managing CSU. What we cover in our episode about living with hives in black skin: Identifying Hives on Darker Skin: Meka shares the challenge of finding accurate images of hives on darker skin tones, which can complicate the first steps of recognizing your condition and create feelings of isolation. Advocating for Yourself in Healthcare: Meka provides strategies for effective self-advocacy during the diagnosis process, including tips for clear communication with healthcare providers. Building a Support Network: Meka emphasizes the value of connecting with others who share similar experiences, including support groups and online communities. Managing Symptoms & Minimizing Scars: Meka offers practical advice for managing CSU symptoms, reducing scarring, and strategies to avoid scratching.

Chronic hives (urticaria) don't look the same on everyone, and for people with skin of color, this can lead to confusion, misdiagnosis, and frustrating delays in treatment. Dr. Ama Alexis joins Dr. Gupta and Kortney to discuss the unique challenges of diagnosing and managing urticaria in skin of color. Chronic spontaneous urticaria (CSU) can be especially tricky to identify in patients with darker skin tones, where traditional medical resources and visual aids often fall short. Dr. Alexis explains how CSU appears differently in skin of color, discussing the difficulty of capturing hives on black and brown skin and offering advice for photographing hives to share with your doctor. Dr. Gupta and Dr. Alexis also delve into the lack of diversity in clinical research and medical literature, exploring how these gaps contribute to mistrust and delays in treatment for patients of color. We end with a discussion on whether patients have better outcomes with providers who reflect the patient's background. What we cover in our episode about chronic urticaria in skin of color: Identifying CSU in Darker Skin Tones: Dr. Alexis shares insights on how hives appear on darker skin and gives tips for photographing hives accurately. Limited Visual Resources for Skin of Color: We discuss how a lack of reliable images for darker skin often leads to confusion and feelings of isolation. Provider Training and Diagnosis Delays: Dr. Alexis highlights how limited training in diagnosing skin conditions across all skin tones contributes to delays in care. Collaborating on a Treatment Plan: Tips for patients on advocating for inclusive care, with guidance on both over-the-counter and prescription options. Cultural Sensitivity in Healthcare: Dr. Alexis shares ways healthcare providers can foster shared decision-making to improve outcomes for patients of color. More resources about chronic hives in skin of color:  Chronic Urticaria Management, Resources & Glossary of Terms What is Chronic Urticaria Chronic Hives: 10 Actions to Support Mental Health Chronic Spontaneous Urticaria Series This episode is produced in partnership with Allergy & Asthma Network, with special thanks to Genentech for sponsoring this episode.

Are you frustrated by the health insurance approval process for medication?  Many patients may not know what their doctors are doing behind the scenes when dealing with health insurance, and many doctors may feel overwhelmed by this process. There is a silver lining! Tools exist to help patients and providers better navigate the complexities of health insurance. Elizabeth Johnson joins Dr. G and Kortney to share her expertise on overcoming the hurdles of securing medication approvals. She explains the biggest challenges healthcare providers face when working with insurance companies. She offers practical tips to navigate the approval process more efficiently. Together with Dr. G, they discuss the lack of health insurance education for providers and the burden this places on medical staff. They also explore available resources and tools for healthcare professionals and stress the importance of incorporating insurance education early in medical training. What we cover in our episode about health insurance from the provider's side: Provider Challenges: Elizabeth explains the common hurdles doctors face in securing medication approvals, from paperwork to insurance denials. Navigating Insurance Companies: We explore the complexities of insurance approvals, from prior authorizations to the importance of good note-taking. NAMAPA Toolkit: Elizabeth introduces the NAMAPA toolkit, designed to assist healthcare providers in navigating all aspects of health insurance. Insurance Education: We highlight the need for insurance education during med school, residency and fellowship. Health Insurance Resources: Elizabeth shares strategies to ensure healthcare professionals have the tools to handle medication approvals and the resources available from pharmaceutical companies. More resources:  Medication Access Coordinator Training From NAMAPA Health Insurance Coverage in the United States Why was my prescription denied by insurance? Health Insurance for Asthma and Allergies Choosing the Right Health Insurance Plan Navigating Insurance Denials and Filing Appeals NAMAPA: National Association for Medication Access and Patient Advocacy Medication Access Network MedicoCX

Has your medication been denied? Now what? Before patients can access medications—whether it's inhalers or biologic therapies—they often have to jump through many hoops to get insurance approval. Navigating the world of health insurance approvals for medication can be overwhelming for both patients and providers. In this episode, we break down what to expect, what you can do, and how to advocate for yourself throughout the process. Lacey Varnon from the National Association of Medication Access and Patient Advocacy (NAMAPA) joins Dr. G and Kortney to dive into the complex world of health insurance. Lacey shares insights into common reasons for medication denials, how to appeal them, and how patients and healthcare providers can work together for better outcomes. What We Cover in Our Episode About Health Insurance Approvals for Medications: Health Insurance Basics: Understanding essential terms like payer and formulary. Navigating Insurance Approvals: Tips for a smoother process, understanding prior authorization, and common reasons for medication denials. Teamwork Between Patients and Providers: How patients and doctors can collaborate to improve chances of approval and streamline the documentation process. The Appeals Process: A step-by-step guide to appealing denials and ensuring access to necessary treatments. Support Programs & Resources: Insights into sample programs, bridge programs, and tools to help patients through the approval process. More resources about health insurance denials and appeals:  Health Insurance Coverage in the United States Why was my prescription denied by insurance? Health Insurance for Asthma and Allergies Choosing the Right Health Insurance Plan Navigating Insurance Denials and Filing Appeals NAMAPA: National Association for Medication Access and Patient Advocacy Medication Access Network This episode is made in collaboration with the National Association of Medication Access and Patient Advocacy (NAMAPA). We thank Amgen for sponsoring this episode.  

Are you curious about how biologic medications are transforming the treatment of asthma, eczema, allergies, and more? Dr. Perdita Permaul joins Dr. Gupta and Kortney to discuss the available biologic medications for allergic conditions. We walk through the eight biologics currently available for allergic diseases, explaining how these medications target different parts of the immune system to treat allergic conditions more effectively than traditional medications. Dr. Permaul explains how biologics have evolved since 2003 and how they are changing the way allergic conditions are treated. She also explains why some of the biologics treat multiple diseases, whereas some are only approved for one.  What we cover in our episode about the available biologics for allergic conditions How biologics work for allergic conditions: We unpack how biologic medications target specific parts of the immune system, reducing inflammation and improving the quality of life for patients with allergic diseases. History and evolution of biologics: Dr. Permaul walks us through the timeline of biologics, starting with Xolair in 2003 and how these treatments have expanded to target other conditions over time. Which biologics treat which conditions: From asthma and eczema to food allergies and nasal polyps, we break down which biologics are available and how they help patients with allergic conditions. Future of biologics: Dr. Permaul discusses the potential of biologics to be used for more conditions in the future, including ongoing research into food allergy treatments. Biologics Cheat Sheet Below is a list of the 8 biologics discussed in this episode. We have briefly outlined their mechanism of action along with the approved conditions and ages the drug is available for presecription.  Omalizumab (Xolair) Xolair works by binding to IgE to prevent allergic reactions. It has since been approved for chronic hives, nasal polyps, and food allergies. Allergic asthma: 6+ Chronic idiopathic urticaria (hives: 12+ Chronic rhinosinusitis with nasal polyps (CRSwNP): 18+ Food allergies:1+ Mepolizumab (Nucala) Targets and blocks interleukin-5 (IL-5) play a key role in the activation and priming of eosinophils, a type of white blood cell that causes inflammation in asthma. Eosinophilic Asthma: 6+ CRSwNP: 18+ Eosinophilic Granulomatosis with Polyangiitis (EGPA): 18+ Hypereosinophilic Syndrome: ≥6 months Reslizumab (Cinqair) Targets and blocks interleukin-5 (IL-5). Eosinophilic asthma: 18+ Benralizumab (Fasenra) Binds to the IL-5 receptor, preventing eosinophils from growing and causing inflammation. Eosinophilic asthma: 6+ Eosinophilic Granulomatosis with Polyangiitis (EGPA): 18+ Dupilumab (Dupixent) Targets and blocks IL-4 and IL-13 to reduce inflammation Asthma: 6+ Atopic Dermatitis: 6 months+ CRSwNP: 18+ Eosinophilic Esophagitis (EoE): 1+ (> 33 lbs) Approved for prurigo nodularis (PN): 18+ Tezepelumab (Tezspire) Blocks thymic stromal lymphopoietin (TSLP). Asthma: 12+ Tralokinumab (Adbry, Adtralza) Targets and neutralizes interleukin-13 (IL-13). Atopic dermatitis: 12+ Lebrikizumab (Ebglyss) Targets and neutralizes interleukin-13 (IL-13). Atopic dermatitis: 12+ (> 40 lbs) ________ This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi-Regeneron for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement. Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Do food allergies impact all communities in the same way?  Dr. Vivian Hernandez-Trujillo joins Dr. G and Kortney to discuss the impact of health disparities on allergy outcomes within the Hispanic and Latino communities. Dr. Hernandez-Trujillo highlights the challenges posed by immigration status, language barriers, and cultural factors that contribute to unequal access to healthcare. These disparities often lead to difficulties in managing conditions like food allergies and asthma. Dr. Hernandez-Trujillo emphasizes the importance of having an advocate in the healthcare system. Dr. G and Dr. Henandez-Trujillo discuss how building a strong relationship with your doctor is key to better outcomes.  Dr. Hernandez-Trujillo also addresses how cultural beliefs and practices within the Hispanic community influence the understanding and management of food allergies and the need for healthcare providers to enhance their cultural competency. What we cover in our episode about health disparities in the Hispanic and Latino Communities: Health Disparities: Immigration status and language barriers significantly impact healthcare access and outcomes in the Hispanic community. Role of an Advocate: Why it is important to have an advocate and maintain a strong relationship with your healthcare provider to navigate the healthcare system. Challenges with Allergy Testing: What are the difficulties the Hispanic population faces with allergy testing, including issues related to insurance coverage? Cultural Beliefs and Practices: How cultural beliefs and practices within the Hispanic community influence the understanding and management of food allergies. Cultural Competency: How healthcare providers can enhance their cultural competency to better serve Hispanic patients. About Our Guest Dr. Vivian Hernandez-Trujillo is a board-certified allergist and immunologist at Nicklaus Children's Hospital, where she specializes in treating allergies and immune conditions in children. Dr. Hernandez-Trujillo is deeply committed to addressing health disparities and improving healthcare access for underserved communities. She is actively involved in research and education, focusing on culturally competent care and advocating for patients within the Hispanic community. Her clinical interests include food allergies, asthma, and other allergic conditions. More resources about XXX:  ¿Qué es una alergia alimentaria? GoogRx Espagñol  Serie de conferencias virtuales Unidos Hablemos

Starting biologic therapy can be life-changing, but navigating the process isn't always easy. Dr. William Anderson joins Dr. Gupta and Kortney to break down the essential steps for starting biologic therapy, covering everything you need to know before beginning treatment. Biologics are at the forefront of managing chronic allergic diseases like asthma and eczema, offering targeted, personalized care that can improve patients' quality of life. However, accessing these medications often requires navigating a maze of insurance approvals, prior authorizations, and specialty pharmacies. We dive deep into the challenges patients face when starting biologics—understanding how to get coverage, managing co-pays, and coordinating with specialty pharmacies, all while handling the logistics of administering the medication. As someone who has just started a biologic herself, Kortney shares her own experience and reflects on how this episode provides the exact information she wished she'd had a few months ago. What we cover in our episode about starting a biologic medication Getting informed before starting biologic therapy: Dr. Anderson explains why reviewing your medication's patient website is a great first step. These resources often include videos and important details about the treatment. Navigating insurance and coverage: Insurance is often the biggest hurdle to starting biologics. Dr. Anderson highlights the role your doctor plays in this. Additionally, we discuss the importance of understanding your coverage, prior authorization, and working with specialty pharmacies to ensure you get the medication. Administration and storage of biologics: Whether it's self-injection or infusion at a clinic, we explain how biologics are administered. Dr. Anderson also provides tips on proper storage, including refrigeration and traveling with biologics. Vaccines and biologics: Find out whether patients on biologic therapy should avoid live vaccines and how inactivated vaccines like the flu shot are generally safe to take. Long-term planning for biologics: Learn about the regular follow-ups and monitoring that are part of managing biologic therapy. Dr. Anderson discusses the importance of staying on track with your doses and follow-up appointments to ensure your biologic works effectively. About our biologics expert, Dr. William Anderson Dr. William Anderson, is a board-certified pediatric allergist and immunologist at Children's Hospital Colorado. With a focus on treating children with complex allergic conditions such as asthma, eczema, and food allergies, Dr. Anderson is known for his patient-centered approach. He has extensive experience in biologic therapies and is dedicated to improving the quality of life for patients through personalized care. Dr. Anderson also actively participates in clinical research, staying at the forefront of advances in allergy and immunology treatments. More resources about biologic therapies and the conditions they treat:  A systematic review and expert Delphi Consensus recommendation on the use of vaccines in patients receiving dupilumab: A position paper of the American College of Allergy, Asthma and Immunology Biologic Medications Overview Understanding Asthma Allergies Explained Managing Food Allergies Understanding Eczema What if I Can't Afford My Eczema Medication? What if I Can't Afford My Asthma Medication? This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi-Regeneron for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

Curious about what's fact and what's fiction when it comes to biologic medications? We're uncovering the truth behind the most pervasive myths about biologic medications with guest Dr. Cedric “Jamie” Rutland. Biologics are revolutionizing the treatment of allergic diseases like asthma and eczema, but misconceptions about their effectiveness, safety, and usage still persist. Dr. Rutland sets the record straight, debunking myths that may be clouding your understanding and decision-making process. From whether biologics are a cure to concerns about long-term safety and side effects, this episode tackles the most common myths head-on. Dr. Rutland breaks down what biologic therapy truly offers, helping you make informed decisions about your treatment options. What we cover in our episode about biologics facts   Are biologics a cure? Dr. Rutland explains that biologics help manage symptoms, but they are not a complete cure. Biologics vs. traditional medications: We clarify how biologics differ from traditional medications in the way they target the immune system at a molecular level. Do biologics have severe side effects? We dispel myths about severe side effects. Long-term effectiveness of biologics: Dr. Rutland talks about how biologics maintain effectiveness over time for most patients. Do you have to stay on biologics for life? Learn how long patients typically stay on biologic treatments and whether they are lifelong therapies. When should biologics be considered? We address the myth that biologics are only for when all other treatments have failed and discuss when biologics should be introduced. Can you stop other medications while on biologics? Dr. Rutland explains that biologics are often used alongside other medications, not as a replacement. Who can use biologics? We debunk the myth that biologics are only for adults or that they can't be used if you have multiple health issues. Biologics and cancer risk: A common concern, but Dr. Rutland explains the actual risks and dispels the misconception that biologics cause cancer. Are biologics immunosuppressive? We discuss how biologics work on the immune system without broadly suppressing it like other treatments might. Biologics in medical practice: Dr. Rutland talks about the role of doctors and financial incentives, explaining why doctors prescribe biologics and how they make treatment decisions. Do biologics work immediately? Dr. Rutland sets the record straight on how long it typically takes for biologics to start working. Biologics are not experimental: Biologics have been widely studied and are not experimental treatments.   Administration of biologics: We address the myth that biologics must be administered only in hospitals, explaining how patients can receive them at home or in clinics. Biologics are not interchangeable: Dr. Rutland explains the importance of sticking with the biologic prescribed specifically for a patient's condition. Prescribing biologics: While specialists typically prescribe biologics, we explore how general practitioners can also be involved in the process. Lifestyle changes and biologics: We discuss the misconception that biologics eliminate the need for lifestyle changes. Are biologics unnecessary for mild symptoms? Dr. Rutland explains that biologics are not only for severe symptoms but can also be considered for other cases. More resources about biologic therapy and the conditions they treat:  https://biologicmeds.org/ https://allergyasthmanetwork.org/what-is-asthma/ https://allergyasthmanetwork.org/allergies/ https://allergyasthmanetwork.org/food-allergies/ https://allergyasthmanetwork.org/what-is-eczema/

What are biologic medications, and how can they help people with allergic diseases? We discuss biologic medications with Dr. Berger, a leading expert in biologic therapy for allergic diseases. Since the first biologic was introduced in 2003, these treatments have advanced significantly. By targeting the root causes of inflammation, biologics offer a more precise, personalized approach to treating conditions like asthma and eczema. Unlike traditional medications, biologics are a breakthrough, opening the door to tailored care that improves patients' long-term symptom control and quality of life. Dr. Berger explains biologic medications, how they work at a molecular level, and how they impact the immune system. As Kortney recently started biologic therapy, we also get a firsthand account of patients' decision-making process and concerns when considering biologic treatments. These innovative therapies not only control symptoms but can transform the daily lives of people living with chronic allergic diseases, providing hope for better, long-term outcomes. What we cover in this episode about the basics of biologic medications: What is a biologic medication? Dr. Berger explains how biologic medications differ from traditional treatments by focusing on precision-based medicine, offering a revolutionary way to target specific aspects of the immune system. How biologic therapies target molecular inflammation: Learn how biologic treatments act on specific inflammatory molecules, offering hope for better control and relief for patients with severe asthma, eczema, and more. Do biologics suppress the immune system? We address common questions about biologic therapy, its effects on the immune system, and potential side effects. The evolution of biologic treatments. A look at how biologic medicine has advanced since 2003 and its role in reshaping asthma therapy and other allergic disease treatments, providing exciting new options for patients. Improving quality of life for allergic disease patients with biologics. We discuss how, for many, biologics have been life-changing. Steps for patients considering biologic treatment. Dr. Berger offers practical advice for patients interested in discussing biologic therapy with their healthcare providers. About our biologic medication expert - Dr. Berger Dr. William E. Berger is a past Clinical Professor in the Department of Pediatrics at the University of California-Irvine and served as Medical Director of Southern California Research in Mission Viejo. He is a board-certified allergist and immunologist with a distinguished career, including roles as President of the American College of Allergy, Asthma & Immunology and as Medical Staff Allergist for the U.S. Olympic Swim Team. Dr. Berger has published over 200 peer-reviewed articles and authored books like Asthma for Dummies, focusing on allergy and asthma treatments. He is widely recognized as an expert in his field, frequently appearing on major media outlets like CNN and Good Morning America. More resources about biologic therapy:  https://biologicmeds.org/ https://allergyasthmanetwork.org/what-is-asthma/ https://allergyasthmanetwork.org/allergies/ https://allergyasthmanetwork.org/food-allergies/ https://allergyasthmanetwork.org/what-is-eczema/ This podcast is made in partnership with The Allergy & Asthma Network. Thanks to Sanofi-Regeneron for sponsoring today's episode. While they support the show, all opinions are our own, and sponsorship doesn't influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

There's never been a better time to be a CSU patient, with cutting-edge therapies and revolutionary treatments just around the corner. As research accelerates, new and promising options that could significantly improve the quality of life for those living with Chronic Spontaneous Urticaria are coming to market. In this episode, Dr. Matthew Zirwas joins us to discuss the latest advancements in treating CSU, offering invaluable insights into both current and emerging treatment options. With his extensive experience and patient-centred approach, Dr. Zirwas breaks down the complexities of CSU and highlights how these new therapies can make a real difference. This podcast was made in partnership with Allergy & Asthma Network. We thank Novartis for sponsoring this podcast. What We Cover in Our Episode About Emerging Chronic Spontaneous Urticaria Treatments: How Dr. Zirwas explains CSU to his patients: Discover the patient-friendly explanations that help demystify CSU and empower patients to learn more about their disease. When to start with a biologic: Learn about the decision-making process for initiating biologic therapies like Xolair (omalizumab) and when they are most appropriate. The new medications coming to market: Get an overview of the latest advancements, including: Dupixent (dupilumab): A biologic administered via injection that targets key pathways in the inflammatory response. Remibrutinib: A BTK (Bruton tyrosine kinase) inhibitor available as a pill that blocks a crucial enzyme in mast cell activation. Barzolvolimab: A promising biologic that targets the C KIT receptor on mast cells to reduce their number. Shared decision-making with these medications: Explore strategies for choosing the most appropriate treatment in a rapidly evolving therapeutic landscape. Research into the underlying cause of CSU: What's happening on the research front to uncover the root causes of CSU. About Our Guest Dr. Matthew Zirwas, MD, is a board-certified dermatologist and a nationally recognized expert in allergy patch testing, psoriasis, and eczema. He founded the Bexley Dermatology Research Clinic, offering patients access to the latest treatment options before they are widely available. Dr. Zirwas also serves as a dermatologic advisor for several companies, including ALL Laundry Detergent and Cerave, and contributes to Women's Health Magazine. Learn more about Dr. Zirwas. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.html Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Did you know that the month of September sees a drastic rise in asthma attacks and hospitalizations? Dr. G and Kortney delve into the challenges that asthmatics face during the fall season, also known as "peak week." Despite what the name suggests, asthma cases start to rise in the second week of September and continue into early October before returning to normal levels. We begin by defining asthma and then explore why asthma attacks are more prevalent in September. We discuss the role of germs and viruses, indoor and outdoor allergens, and cold weather in exacerbating asthma symptoms. Dr. G also shares tips on how to lessen your exposure to these triggers. Additionally, we cover the importance of having an asthma action plan and the significance of well-controlled asthma. Dr. G also discusses the financial aspects of asthma management and offers advice on how to discuss this with your doctor. >>>> Listener survey: https://forms.gle/6Pb2PGq6nuVReasZ6 What we cover in our episode about the rise in September asthma attacks Why September is Peak Asthma Season: Explore why asthma attacks increase in the fall and what you can do to prepare. The Role of Germs and Viruses in Asthma: Understand how illnesses can trigger asthma and learn tips for staying healthy. Indoor and Outdoor Allergens: Discover how common allergens like dust mites, pet dander, ragweed, and mold can affect asthma, and what you can do to limit exposure. Preparing for Peak Week: Essential steps to take before asthma season hits, including scheduling doctor visits and creating an action plan. Asthma Management Tips for Different Age Groups: Advice for school-aged children and elderly patients to ensure they receive the best care. More resources about asthma peak week:  Asthma and Allergy Forecast: pollen and allergen count https://allergyasthmanetwork.org/weather/ 10 Ways to Stay Healthy During the September Asthma Peak Week https://allergyasthmanetwork.org/news/10-ways-to-stay-healthy-during-september-asthma-peak/ Seasonal allergies: https://allergyasthmanetwork.org/news/seasonal-allergies/ Asthma attack: https://allergyasthmanetwork.org/what-is-asthma/asthma-attack/ What if I Can't Afford My Asthma Medication? https://allergyasthmanetwork.org/what-is-asthma/what-if-i-cant-afford-my-asthma-medication/  Asthma Management and Control (2:2:1 Rule) https://allergyasthmanetwork.org/what-is-asthma/asthma-management-and-control/ AirQ https://www.airqscore.com/en/main-page.html  ACT Test https://www.asthmacontroltest.com/welcome/  We want to thank AstraZeneca for sponsoring this episode. Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

This episode is a quick-fire round covering the misunderstood aspects of chronic spontaneous urticaria (CSU), a condition that perplexes many due to its spontaneous nature. With over 1.7 million people affected, it's more common than you might think and deserves a closer look. Despite its prevalence, many misconceptions persist about what causes CSU, its symptoms, and how it can be treated. Kortney and Dr. Gupta tackle the myths and misconceptions around CSU. Unpacking its impacts on quality of life and the challenges those living with the condition face. They explore the realities of living with CSU, from the pervasive itch to the emotional toll it can take. Whether you're a patient, caregiver, or healthcare professional, this episode offers valuable insights into the realities of managing CSU. This podcast was made in partnership with Allergy & Asthma Network. We thank Novartis for sponsoring this podcast. The chronic spontaneous urticaria myths and misconceptions we cover in our episode CSU is caused by allergies. CSU is contagious. CSU is a rare condition. CSU is not a serious condition. Stress is the main cause of CSU. CSU only affects the skin. CSU will go away quickly. There isn't any treatment for chronic hives. Antihistamines are the only treatment for CSU. Changing your diet will help CSU. CSU can be cured. Once CSU goes away, it will never come back again. Men and women are equally affected by CSU. You can always pinpoint the exact cause of hives in patients with CSU. Autoimmune conditions are more common in people with CSU. Scratching hives is harmless. Once my hives are controlled, I need to be on the medication forever. All hives look the same. Only adults get CSU. CSU hives are always accompanied by other allergic symptoms like swelling or difficulty breathing. Having CSU doesn't affect quality of life. The itch in CSU is not a big deal. Allergy testing will help me figure out why I have CSU. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.html Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Imagine being so itchy that you'd consider cutting off your skin just for relief. That's what it can be like living with chronic spontaneous urticaria. We sit down with Heather, a patient living with chronic spontaneous urticaria, as she candidly shares her experiences from the initial diagnosis to navigating the complex landscape of treatments and mental health support. Her story sheds light on the day-to-day struggles and triumphs of managing CSU, offering hope and practical advice for those in similar situations. Dr. G unpacks Heather's diagnosis and treatment journey, including antihistamines and Omalizumab. Dr. G also highlights the importance of managing mental health. Kortney shares her experience of itch and, with Heather, discusses the impact of chronic itching on quality of life and how to explain this to friends and family. What we cover in our episode about living with chronic spontaneous urticaria Heather's Journey with CSU: Heather shares her initial diagnosis and the rollercoaster of emotions and challenges that followed. Anaphylaxis vs. CSU: Understanding the critical differences between these two conditions. Finding the Right Treatment Plan: The journey to discovering effective medications like antihistamines and the injectable - Omalizumab (Xolair). Mental Health Support: The importance of therapy and online resources in managing life with CSU. Management strategies: Heather shares what works for her in managing exacerbating situations.  Advice for New Patients: Heather offers valuable advice for those beginning their CSU journey. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  More information about Omalizumab (Xolair): https://www.xolair.com/chronic-spontaneous-urticaria.html Episode Heather talks about where she learned to call her condition Lynda: https://www.itchpodcast.com/episodes/71-living-with-mastocytosis  Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Yes, there are more options than antihistamines to treat chronic spontaneous urticaria. We dive into them!  Dr. Sheila Gogate joins us to discuss the chronic spontaneous urticaria (CSU) treatments currently available for patients. Dr. Shaila Gogate outlines the treatment journey for CSU with an emphasis on shared decision-making.   This episode emphasizes the importance of following treatment guidelines and adjusting medications as needed. We discuss the available treatments for urticaria, including antihistamines, omalizumab (Xolair for hives), and Cyclosporine. The episode also explores the journey of managing CSU symptoms through both medical and non-medical approaches. What we cover in our episode about chronic spontaneous urticaria treatments Treatment Path and Guidelines: Overview of doctors' steps to treat CSU. The importance of shared decision-making in the treatment plan.  Antihistamines: Role of oral antihistamines and H2 blockers in managing hives, dosing options, side effects, when to change medications, and how to choose the right antihistamine. Advanced Treatments: If antihistamines fail, the following steps include omalizumab (Xolair) injections or Cyclosporine. An overview of both dosing options and side effects. Emerging Therapies: Treatments like Remibrutinib and Dupilumab. Quality of Life and Non-Medical Management: The Urticaria Activity Score (UAS7). Mental health screening for CSU patients and strategies like stress reduction and if special diets are effective. About our guest, Dr. Shaila Gogate Dr. Shaila Gogate, board-certified by the American Board of Allergy & Immunology, has been with Colorado Allergy & Asthma Centers since 2014. She completed her medical education at Chicago Medical School, her residency at Washington University, and her fellowship at National Jewish Health in Denver. Dr. Gogate has served as an Assistant Professor at the University of Colorado, has extensive clinical research experience, and emphasizes strong patient-provider communication to develop effective treatment plans. More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/  How Mast Cells Work Video_ mast cell video - explanation of mast cell (07:20): https://youtu.be/OF7tBIvMK_0?si=osJaIpTrivUP1Owr Urticaria Activity Score (uas7): https://www.mdcalc.com/calc/10226/urticaria-activity-score-uas More information about XOlair: https://www.xolair.com/chronic-spontaneous-urticaria.html

How is the black community impacted by food allergies? Dr. Carla Davis joins Dr. G and Kortney to discuss the impact of social determinants of health on food allergy outcomes within the Black community. Dr. Davis highlights historical factors like redlining and insurance disparities that exacerbate health disparities, resulting in higher prevalence rates of food allergies and multiple allergies among Black patients. These disparities often lead to increased emergency room visits and barriers to accessing allergen-free foods, compounded by socioeconomic challenges and food insecurity. Dr. Davis also underscores how cultural differences significantly influence the management of food allergies within families, particularly during gatherings, and emphasizes the crucial role of media representation in raising awareness and promoting acceptance. We discuss the critical need for increased Black representation in research trials, recognizing the challenges posed by longstanding mistrust in the medical community among Black patients. Key Points Covered in This Episode: Health Disparities: Social factors significantly impact food allergy outcomes in the Black community. Limited Healthcare Access: Redlining and insurance disparities restrict healthcare access, worsening health outcomes. Food Insecurity: Challenges in accessing allergen-free foods are heightened by food insecurities and food deserts. Cultural Factors in Food Allergy Management: Cultural influences play a crucial role in managing food allergies within families. Resources for Food Allergies: Essential support from food banks and allergy organizations for managing allergies and food insecurity. Communication Tips for Patients: Practical advice for effective communication and advocacy with healthcare providers. Historical Mistrust of the Medical Community: Historical discrimination contributes to mistrust in healthcare, affecting access and outcomes. Helpful Resources Health Disparities in Allergy, Asthma and Immunologic Diseases (New Webinar July 16, 2024): https://allergyasthmanetwork.org/webinars-updates/health-disparities-diseases/ Black People Like Me Virtual Conference Series 2024: https://allergyasthmanetwork.org/trusted-messengers-project/black-people-like-me-2024/ Food Allergy Resources: https://allergyasthmanetwork.org/allergies/  School Plans for Students with Food Allergies: https://allergyasthmanetwork.org/news/school-plans-students-food-allergies/ Food Equality Initiative - Food Allergy Friendly Food Bank Resource: https://www.foodequalityinitiative.org/

How do you know if your hives are chronic spontaneous urticaria?  Join Kortney and Dr. Payel Gupta in the second episode of this chronic spontaneous urticaria (CSU) series as they delve into the diagnostic journey of CSU.  Have you wondered if the path to a chronic spontaneous urticaria diagnosis is long? CSU can feel like a very complex disease to diagnose due to the lack of identifiable triggers, but this episode breaks down the steps healthcare professionals take to diagnose CSU.  Dr. G clarifies how allergists' and dermatologists' roles differ in diagnosing CSU. The episode emphasizes the importance of a detailed medical history and the tests involved in ruling out other conditions. It also describes the journey of determining CSU from other skin and allergic reactions through meticulous evaluation and specific testing methods. What we cover in our episode about diagnosing Chronic Spontaneous Urticaria: Introduction to CSU Diagnosis: CSU has no identifiable triggers, making diagnosis a process of elimination. Role of Specialists: Patients often start their diagnosis journey at urgent care, after which they consult allergists and dermatologists depending on the severity and symptoms of hives. Detailed Medical History: Essential questions cover medications, infections, travel history, and other health changes to rule out underlying causes. Physical Examination: Doctors check if hives are “blanchable” to differentiate from other conditions like vasculitis. Ruling out other Conditions: This involves evaluating other conditions in which hives are a symptom, such as mast cell disease or various autoimmune diseases.  Necessary Tests: Doctor's apprehension about doing a food allergy test unless necessary. Other tests include looking at blood count (CBC with differential) and inflammation (ESR or CRP).  More resources about chronic spontaneous urticaria:  Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticari This episode is produced in partnership with Allergy & Asthma Network. We want to thank Novartis for sponsoring this episode. Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

Do you get hives and have no clue why? Then this episode is for you! Join Kortney and Dr. Gupta as they unpack chronic spontaneous urticaria (CSU) in a six-part series. You may also have heard of this condition called chronic idiopathic urticaria or spontaneous urticaria. In this first episode, Kortney and Dr. Gupta dive into the nitty gritty of chronic spontaneous urticaria. They define the medical term "urticaria," commonly known as hives, and discuss how CSU differs from other forms of urticaria. They dive into the symptoms, including the itchy and transient nature of hives, and emphasize that CSU can vary in appearance depending on skin tone.  What may seem complicated in chronic spontaneous urticaria is that there are no triggers. Instead, Dr. G walks us through the factors that may be culprits to CSU flares, such as stress and certain medications, and she highlights the impact of autoimmune conditions on CSU prevalence. What we cover in our episode about chronic spontaneous urticaria: Definition and symptoms of urticaria (hives) Differences between chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CINDU) The definition of chronic spontaneous urticaria and its symptoms The role of histamine in hives The mechanisms of itch and why scratching feels so good Factors that can exacerbate chronic spontaneous urticaria Populations most affected by chronic spontaneous urticaria The average duration of CSU symptoms Is chronic spontaneous urticaria curable More resources about chronic spontaneous urticaria: Chronic Urticaria Management, Resources & Glossary of Terms: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/management-and-resources/ What is Chronic Urticaria: https://allergyasthmanetwork.org/health-a-z/chronic-urticaria/ Episode 39: urticaria what causes hives? https://www.itchpodcast.com/episodes/39-urticaria This episode is produced in partnership with The Allergy & Asthma Network. We thank Novartis for sponsoring this episode and the series.  Disclaimer: This podcast is for informational purposes only and does not substitute professional medical advice. Always consult with your healthcare provider for any medical concerns.

As temperatures rise and weather patterns become more unpredictable, the effects of climate change on respiratory health become even more noticeable. Dr. Stephanie Lovinsky-Desir, an expert in respiratory health, joins Dr. G and Kortney to discuss how climate change exacerbates respiratory conditions like asthma, particularly affecting vulnerable populations.  The episode explores why we should consider the connection between climate change and asthma. Understanding the mechanisms behind it is crucial. Dr. Lovinsky-Desir explains how increased temperatures lead to higher levels of air pollution and create “heat islands" in urban areas. Heat islands are urban areas that are significantly warmer than their surrounding rural areas due to human activities. These islands intensify health risks by trapping heat and pollutants, worsening air quality and increasing respiratory distress. Dr. Lovinsky-Desir and Dr. G share practical measures that are easy to implement and can significantly help us navigate poor air quality. These include wearing masks during high pollution and monitoring air quality through initiatives like the State of the Air Report or your weather app. She also highlights the role of organizations like the American Lung Association in providing resources and support for improving indoor air quality. We hope this episode helps you better understand climate change's impact on air quality, the overall environment, and lung health. Hopefully, you can take meaningful steps towards a healthier future for all. If you are in doubt about the impacts of climate change, this episode is for you! What we cover in our about climate change, air pollution and lung health The relationship between air pollution, air quality and climate change The impact of climate change on season allergies The effect of air quality on lung health The populations most impacted by poor air quality Poor housing and its effects on lung health Programs and resources help make housing healthier  What you can do to keep your lungs safe How to explain to someone why they need to care about climate change and asthma Helpful links More about our sponsor, Chiesi: https://www.chiesiusa.com/ Pollen Report from Allergy Asthma Network: https://allergyasthmanetwork.org/weather/  State of the Air Report from The Lung Association: https://www.lung.org/research/sota Tips to Manage Asthma and Allergies Caused by Climate Change: https://allergyasthmanetwork.org/news/climate-change-what-you-can/ Lifestyle Changes to Manage Asthma: https://allergyasthmanetwork.org/what-is-asthma/lifestyle-changes-to-manage-asthma/

Have you ever searched for information on mast cell disease only to be overwhelmed by alarming topics like cancer and stem cell transplants? Then this episode is for you! Our guest, Dr. Marina Kremyanskaya, joins hosts Dr. G and Kortney to provide insight into the progression of systemic mastocytosis and the available treatment options to improve quality of life and extend lifespan. Dr. Kremyanskaya distinguishes between indolent and aggressive systemic mastocytosis, shedding light on warning signs indicating disease progression. She offers a detailed exploration of treatment approaches for aggressive mastocytosis, highlighting the evolving treatment plan and differing prognosis from indolent cases. Additionally, Dr. Kremyanskayaa delves into the concept of myeloid malignancy, providing insight into the more challenging aspects of advanced systemic mastocytosis progression. We also dive into stem cell transplants as a potential cure for advanced systemic mastocytosis. Dr.  Kremyanskaya explains why this option is not immediately pursued due to the complexity of the procedure and the risk of graft-versus-host disease (GvHD), a potential complication associated with stem cell transplants. What we cover in this episode about advanced systemic mastocytosis: Understanding indolent systemic mastocytosis Signs indicating progression to advanced mastocytosis. Treatment strategies for aggressive mastocytosis and associated prognosis. Explanation of advanced systemic mastocytosis with or without hematologic malignancy. Definition of myeloid malignancy. Understanding the impact of advanced systemic mastocytosis on organs. The effectiveness of early treatment in slowing down the progression. The role of stem cell transplant in treating mastocytosis. Stem cell transplant and associated risks Role of chemotherapy in stem cell transplant. Overview of graft-versus-host disease. Addressing whether stem cell transplant serves as a cure for mast cell disease. Resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Why talk to a hematologist about mast cell disease and systemic mastocytosis treatment? Dr. Douglas Tremblay, a leading hematologist, joins Dr. G and Kortney to discuss the role of a hematologist-oncologist in diagnosing and treating mastocytosis. We discuss bone marrow's vital role in diagnosing and treating systemic mastocytosis.  Dr. Tremblay discusses the latest KIT inhibitors, a promising group of medications, and explains the difference between indolent and advanced systemic mastocytosis. He clarifies how KIT inhibitors work and emphasizes the importance of managing side effects. Finally, Dr. Tremblay provides insights into the future of KIT inhibitor approval and explores the possibility of participating in a clinical trial for Bezulastinib.  What we cover in this episode about treating systemic mastocytosis: What is a hematologist looking at with mast cell disease patients? Mast cell diseases and the role of bone marrow Bone marrow biopsy for systemic mastocytosis  What is a bone marrow biopsy? Information bone marrow biopsy provides for diagnosis KIT mutation  KIT mutation testing in bone marrow and blood (digital droplet PCR) Indolent Mastocytosis versus Advanced Mastocytosis Current research for treating mast cell disease How KIT inhibitors work Do KIT inhibitors weaken the immune system? KIT Inhibitors discussed in this episode: Avapritinib Bezulastinib Elenestinib Are KIT inhibitors a cure for mast cell disease? Determining the tolerance for side effects of medications when researching and adding new medicines for diseases  The meaning of ‘NIB' in the medication names The timeline for the new KIT inhibitors approval The type of patient that can participate in the clinical trials for Bezulastinib Resources about mast cell disease: Dr. Tremblay: https://profiles.mountsinai.org/douglas-a-tremblay Dr. Tremblay's email: douglas.tremblay@mssm.edu  Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/ Current studies enrolling patients: https://tmsforacure.org/clinical-trials/

What is it like when an unpredictable disease like systemic mastocytosis forces you to change the trajectory of your life? As we continue to unpack mast cell disease, Dr. G and Kortney wanted to get the patient's perspective on living with such a complex disease. Tammie joins the podcast to discuss her journey battling mastocytosis, a rare condition affecting mast cells in the body. If you ever feel alone on your chronic health journey, know you aren't! Tammie's resilience and wisdom serve as a beacon of hope. We hope this inspires you to approach your health journey with determination and a sense of community.   What we cover in this episode: Tammie's mastocytosis journey The challenges of not getting a proper diagnosis The pros and cons of being able to google medical conditions What do to when a doctor does not want to take you on as a patient  How Tammie separates the disease from her life  How do you navigate work with a chronic disease? Working with a mental health team How do you ask your family/friends for help Patient's relationship with their healthcare team Pros and cons of an online community for chronic disease and the importance of a real-life community   Connect with Tammie online: TikTok https://www.tiktok.com/@rachelllargentphillips Instagram https://www.instagram.com/tammie_rachell/   Resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Can a low-histamine diet help with mast cell disease? Why is stress a big trigger for mast cell disease? Dr. Milner joins us again to discuss two hot topics in managing mast cell disease. We start by demystifying the low histamine diet and sharing when appropriate. The answer may be different from what you expect or want to hear. We also talk about stress, a topic we are learning impacts so many chronic diseases, especially those related to mast cells. Stress can worsen symptoms, and in this episode, both doctors emphasize the importance of stress management techniques.   What we cover in this episode about low histamine diet and stress management Why go on a low histamine diet? What is histamine intolerance?  How well do low histamine diets work for mast cell disease? The impact of stress on mast cell disease Stresses impact on the gut Stress management is integral in mast cell disease treatment  More resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Where do you begin with mast cell disease treatment when there is such variation among patients?  Dr. Milner is back with us to discuss the difficulties in treating mast cell activation syndrome and mastocytosis. We will discuss the different approaches to treating mast cell disease and the medications used for mastocytosis treatment. Since no single treatment plan works for everyone, we will explore multiple strategies that can be helpful in managing this condition. A note: when you hear MCAS mentioned, it stands for Mast Cell Activation Syndrome. What we cover in our episode about treating mast cell diseases: What are the steps taken to treat mast cell diseases? Histamine blockers: antihistamines for mast cell disease and H2 blockers Mast cell stabilizers: Cromolyn and Ketotifen Xolair  Other medications that have been used but not recommended: aspirin, steroids, Singulair Epinephrine and anaphylaxis Tyrosine kinase inhibitors (TKI) for Mastocytosis: Avapritinib, Midostaurin Safety concerns and side effects of Tyrosine kinase inhibitors  Multidisciplinary approach to managing mast cell disease About our guest - Dr. Josh Milner Joshua Milner, MD, is a renowned leader in discovering and understanding genetic diseases leading to allergic symptoms, including Hereditary Alpha Tryptasemia Syndrome, PLAID, PGM3 deficiency, ERBIN mutation, and others. With a background in biology from MIT and an MD with distinction in immunology from Albert Einstein College of Medicine, Dr. Milner has extensive experience in pediatrics and allergy and immunology, serving as chief of the Laboratory of Allergic Diseases at NIAID. His vision is to leverage genetic variation to improve diagnosis and care for patients with allergic diseases through comprehensive genetic sequencing and functional studies, aiming for personalized medicine and interdisciplinary collaboration in pediatric allergy, immunology, and rheumatology. More about Dr. Milner:  https://www.pediatrics.columbia.edu/profile/joshua-milner-md More resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/ FDA Approves AYVAKIT® (avapritinib) as the First and Only Treatment for Indolent Systemic Mastocytosis: https://ir.blueprintmedicines.com/news-releases/news-release-details/fda-approves-ayvakitr-avapritinib-first-and-only-treatment

Our episode on eyelash allergies was so interesting we had to bring you more from our favorite eye Doc, Dr. Luk. We delve into the fascinating world of eyelash health and hygiene, from the importance of cleanliness to the latest trends like eyelash serums and magnetic extensions. We discuss the importance of hygiene, eyelash serums, and magnetic eyelash extensions. What we cover in this episode on how to clean eyelash extensions: Eyegiene: why you need to clean your eyelashes How to clean your eyelid margin How often should you clean your eyelid margins How to know if it is eczema or blepharitis What to consider when using lash serums Are magnetic eyelash extensions a better alternative to traditional eyelash extensions?

Put on your detective hat because we will be diving into how to diagnose mast cell disease! Dr. G and Kortney are joined by Dr. Josh Milner, one of the top experts in the field of mast cell disease, as they dive into the complexities of diagnosing mast cell disorders, focusing on cases of unexplained anaphylaxis and using this as our guide to understanding all of the tests that doctors do to figure out what is happening with your mast cells.  From histories to blood and urine tests to Darier's sign, bone marrow biopsies and more, we dig into the many tests needed for the detective work diagnosing mast cell disease. We learn that a nuanced approach is required to diagnose mast cell disorders and the importance of thorough evaluation to differentiate between potential causes. This podcast was made in partnership with Allergy & Asthma Network. We thank Blueprint Medicines for sponsoring this podcast. What we cover in our episode about diagnosing mast cell disease: Unexplained anaphylaxis could be linked to mast cell disorders. Diagnostic tools: Blood tryptase test (fast but time-sensitive) Urine metabolite tests (easier, longer window) Skin rash assessment (urticaria pigmentosa) Bone marrow biopsy (serious cases) Symptoms: Sudden episodes, chronic issues like fatigue, depression. About our guest - Dr. Josh Milner Joshua Milner, MD, is a renowned leader in discovering and understanding genetic diseases leading to allergic symptoms, including Hereditary Alpha Tryptasemia Syndrome, PLAID, PGM3 deficiency, ERBIN mutation, and others. With a background in biology from MIT and an MD with distinction in immunology from Albert Einstein College of Medicine, Dr. Milner has extensive experience in pediatrics and allergy and immunology, serving as chief of the Laboratory of Allergic Diseases at NIAID. His vision is to leverage genetic variation to improve diagnosis and care for patients with allergic diseases through comprehensive genetic sequencing and functional studies, aiming for personalized medicine and interdisciplinary collaboration in pediatric allergy, immunology, and rheumatology. More about Dr. Milner:  https://www.pediatrics.columbia.edu/profile/joshua-milner-md More resources about mast cell disease: Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Have you ever wondered why your doctor puts their membership in their bios? Why is it relevant to a patient that your allergist is a member of the ACAAI? This podcast is made possible through Allergy & Asthma Network's partnership with the American College of Allergy, Asthma and Immunology. Dr. G and Kortney had the special privilege of interviewing Dr. Gailen Marshall, the president of the American College of Allergy, Asthma, and Immunology (ACAAI). He explains what the ACAAI, also known as the College, does and why this matters to patients. We learn about the resources provided by the College, which offer patients invaluable support in managing their allergies. From accessing specialized care through the "Find an Allergist" tool to engaging with the ACAAI's educational materials and advocacy opportunities, patients are empowered to take control of their treatment journey. We also dive into Dr. Gailen Marshall's work in psychoneuroimmunology, which sheds light on how both external and internal environments impact allergic reactions. We touch upon Dr. Marshall's Presidential Initiative, CAAPER, which bridges the gap between community and academic allergists, driving innovation in patient treatment. As allergy research continues to advance, Dr. Marshall's leadership underscores the importance of interdisciplinary collaboration and patient-centred care in navigating the complexities of allergic diseases. What we cover in the episode Dr. Marshall's field of study: Psychoneuroimmunology What does the American College of Allergy Asthma and Immunology (ACAAI) do? How is the ACAAI relevant to patients? How can a patient take advantage of the resources the ACAAI has? How can patients be involved with the ACAAI? Why should you see an allergist? Dr. Marshall's Presidential Initiative - Community and Academic Allergist Partnership in Education and Research (CAAPER) About our guest, Dr. Marshall Gailen D. Marshall, Jr. MD, PhD, FACP, is the president of the American College of Allergy, Asthma and Immunology and holds distinguished roles as Chair of Allergy and Immunology, Professor of Medicine and Pediatrics, Vice Chair for Research, Director of the Division of Clinical Immunology and Allergy, and Chief of the Laboratory of Behavioral Immunology Research at the University of Mississippi Medical Center in Jackson.  With a background in both Immunology and Medicine from the University of Texas Medical Branch in Galveston and extensive training at institutions like the University of Iowa and the University of Tennessee at Memphis, Dr. Marshall is renowned for his expertise in integrative approaches to managing inflammatory diseases. His research delves into the impact of psychological stress and environmental factors on immune responses, aiming to identify biomarkers for stress susceptibility. With over 200 publications and active engagement as a speaker in regional, national, and international forums, Dr. Marshall also served as Editor-in-chief of the Annals of Allergy, Asthma and Immunology, showcasing his leadership in the field. Additionally, he plays a vital role in professional societies like the Southern Society for Clinical Investigation, where he serves as Secretary-Treasurer and contributes to various committees, highlighting his commitment to advancing clinical research and education.  

Have you ever considered whether your nasal congestion, IBS, brain fog, and hives are related?  This podcast was made in partnership with Allergy & Asthma Network. We thank Blueprint Medicines for sponsoring this podcast. Dr. Anne Maitland joins us as we delve into the complex world of mast cell disease. From the confusing range of symptoms to the unpredictable nature of each person's experience, we unravel the mysteries that make mast cell disorders so uniquely difficult to tackle. Dr. Maitland is an expert in allergy and immunology and sheds light on the diverse manifestations of mast cell dysfunction, from headaches and nasal congestion to gastrointestinal issues and skin reactions like hives.Dr. Maitland emphasizes the importance of recognizing mast cell dysfunction's impact across different organs for accurate diagnosis and management. What we cover in our episode about mast cell disease: Symptoms of mast cell disease How to connect the dots of mast cell disease symptoms What is a sign that your symptoms are related to mast cells The job of mast cells and their scientific history Is an anaphylactic reaction a mast cell disease? What triggers mast cell disease?  Mast cell targetted medications and how this can hide your symptoms About our guest - Dr. Maitland Dr. Maitland is a highly respected physician and a Fellow of the American College of Allergy, Asthma, and Immunology. She was named New York Times' Super Doctors in 2011 and one of America's Top 21 Women's Doctors by Lifescript.com in 2009. Dr. Maitland is actively involved in creating awareness of immune-mediated disorders and researches to enhance treatments for allergies, asthma, and recurrent infections. She specializes in allergic skin disorders, allergic rhinitis, drug allergies, food allergies/sensitivities, asthma, and recurrent infections.  Dr. Maitland holds an MD and PhD from the University of Pennsylvania and completed her residency in Internal Medicine at Brigham and Women's Hospital in Boston. She also pursued a Fellowship in Allergy and Immunology at Brigham and Women's Hospital and Mount Sinai Hospital in New York. More about Dr. Maitland:  https://www.metrodora.co/anne-maitland https://www.drannemaitland.net/dr-anne-maitland More resources about mast cell disease: Mast Cell Disease page: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/

Are you allergic to your eyelash extensions? Eyelash extensions have become increasingly popular in recent years, offering a way to achieve fuller, longer lashes without the hassle of applying mascara every day. However, some potential risks are associated with eyelash extensions, including allergic reactions. Dr. Janice Luk joins Dr. G and Kortney to discuss eyelash extensions and what happens when things go wrong. We dive into eyelash extension allergies and contact dermatitis, what the reactions look like, how to treat the reactions best and why you need to take care of your biofilm. No one wants to play with their vision or have an allergic reaction around the eye; this episode will help you better understand what could happen and how to prepare your lash extensions properly. What we cover on eyelash extension allergies: What are eyelash extensions? How eyelash extensions differ from what you can do at home What does the allergic reaction to eyelash extensions look like? Contact dermatitis versus an IgE-mediated allergic reaction What glues are being used, and what would cause the reaction? Symptoms and treatment for a lash extension allergy Why you don't want to use over-the-counter medication for your eyes The importance of keeping a clean biofilm Eyegiene Traction alopecia caused by lash extensions When should you seek medical attention for eyelash extension reactions What is the difference between an ophthalmologist and an optometrist