Ophthalmology Journal

Dr. Rajesh Rao sits down with Dr. Sophie J. Bakri and medical student Marie-Michele Macaron to discuss their systematic Review and meta-analysis on the efficacy and safety of anti-VEGF and panretinal photocoagulation for the treatment of proliferative diabetic retinopathy. From their Ophthalmology Retina article, “Anti-VEGF Injections vs. Panretinal Photocoagulation Laser Therapy for Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis.” Anti-VEGF Injections vs. Panretinal Photocoagulation Laser Therapy for Proliferative Diabetic Retinopathy. Macaron, Marie-Michele et al. Ophthalmology Retina, Volume 9, Issue 2, 105 - 121.

Dr. Edmund Tsui interviews authors Dr. Muhammad Z. Chauhan and Dr. Krishna S. Kishor on the risk of uveitis among patients starting topical glaucoma therapy. From their Ophthalmology Glaucoma article, “Incidence of Uveitis Following Initiation of Prostaglandin Analogs versus Other Glaucoma Medications.” Incidence of Uveitis Following Initiation of Prostaglandin Analogs versus Other Glaucoma Medications. Chauhan, Muhammad Z.Amin, Sejal et al. Ophthalmology Glaucoma, Volume 8, Issue 2, 126 – 132.

How accurate are diagnoses from ChatGPT? Can ophthalmologists distinguish between artificial intelligence and human responses? Dr. Tsui speaks with Drs. Jimmy S. Chen and David B. Granet on their Ophthalmology Science article, “Analysis of ChatGPT Responses to Ophthalmic Cases: Can ChatGPT Think like an Ophthalmologist?” Analysis of ChatGPT Responses to Ophthalmic Cases: Can ChatGPT Think like an Ophthalmologist? Chen, Jimmy S. et al. Ophthalmology Science, Volume 5, Issue 1. Sign up for the next Ophthalmology Journal Virtual Club on April 23, 2025, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Dr. Drew Carey speaks with Dr. Tongalp H. Tezel on his study comparing patients with nonarteritic ischemic optic neuropathy (NAION) with healthy non-NAION patients with crowded discs and noncrowded optic discs. From his Ophthalmology article, “Vitreopapillary Findings in Nonarteritic Ischemic Optic Neuropathy versus Healthy Eyes.” Vitreopapillary Findings in Nonarteritic Ischemic Optic Neuropathy versus Healthy Eyes. Hondur, Ahmet M. et al. Ophthalmology, Volume 132, Issue 3, 327 – 334 CALL FOR ABSTRACTS! Now accepting paper, poster, and video submissions through April 8. Imagine presenting at AAO 2025; learn more and submit yours at aao.org/pod25

Dr. Edmund Tsui is joined by Dr. Majda Hadziahmetovic to discuss her meta-analysis and systematic review investigating the effectiveness of systemic and local treatments in slowing autoimmune retinopathy progression. From the Ophthalmology Science article, “Clinical Outcomes of Therapeutic Interventions for Autoimmune Retinopathy: A Meta-analysis and Systematic Review.” Clinical Outcomes of Therapeutic Interventions for Autoimmune Retinopathy: A Meta-analysis and Systematic Review. Kapoor, Ishani et al. Ophthalmology Science, Volume 5, Issue 1. CALL FOR ABSTRACTS! Now accepting paper, poster, and video submissions through April 8. Imagine presenting at AAO 2025; learn more and submit yours at aao.org/pod25

Ophthalmology Editor-in-Chief, Russell Van Gelder, MD, PhD, and our new Associate Editor, Laura Downie, BOptom, PhD, guest host this special episode introducing “Ophthalmology Reviews.”  Ophthalmology Reviews is a new section in our flagship journal for structured systematic reviews and meta-analyses. The two editors discuss the importance of these reviews in our field and what our journal is looking for from authors in these types of submissions. For more information, read their recent editorial in Ophthalmology, “Gargantua, The Scholarship of Synthesis and the Evolution of the Ophthalmology Family Journals” and review our Guide for Authors section on Systematic Reviews and Meta-analysis. If you have any questions about submissions, please contact the editorial staff at aaojournal@aao.org. Gargantua, The Scholarship of Synthesis and the Evolution of the Ophthalmology Family Journals. Van Gelder, Russell N. Downie, Laura E. Ophthalmology, Volume 132, Issue 1, 12 – 13.

A revelation while scuba diving leads to a novel device designed to reduce IOP pressure. Dr. Emily Schehlein speaks with Drs. Katherine S. Peters and Daniel Terveen about their study on the FSYX Ocular Pressure Adjusting Pump, from their recent Ophthalmology Glaucoma article, “Manometric Intraocular Pressure Reduction with Negative Pressure Using Ocular Pressure Adjusting Pump Goggles” Manometric Intraocular Pressure Reduction with Negative Pressure Using Ocular Pressure Adjusting Pump Goggles. Peters, Katherine S. et al. Ophthalmology Glaucoma, Volume 8, Issue 1, 22 – 27.

How do GLP-1 receptor agonists and metformin affect glaucoma risk in patients with Type 2 diabetes? Join Dr. Ike Ahmed and Jawad Muayad as they discuss the data on diabetes treatments and glaucoma risk with Dr. Emily Schehlein. From their Ophthalmology article, “Comparative Effects of Glucagon-like Peptide 1 Receptor Agonists and Metformin on Glaucoma Risk in Patients with Type 2 Diabetes.” Comparative Effects of Glucagon-like Peptide 1 Receptor Agonists and Metformin on Glaucoma Risk in Patients with Type 2 Diabetes. Muayad, Jawad et al. Ophthalmology. In press.

What is the relationship between blood pressure and visual field progression? Can systemic arterial blood pressure be used to assess the risk of glaucomatous progression? Dr. Emily Schehlein finds out from Dr. David S. Greenfield, author of Ophthalmology's “Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression: The Vascular Imaging in Glaucoma Study.” Relationship between Blood Pressure and Rates of Glaucomatous Visual Field Progression. Donkor, Richard et al. Ophthalmology, Volume 132, Issue 1, 30 - 38

What are the risk factors and frequency of recurrence in patients with acute anterior uveitis? Dr. Edmund Tsui and Dr. Rachael L. Niederer delve into the findings of her recent Ophthalmology study, “Risk of Recurrence in Acute Anterior Uveitis.” Risk of Recurrence in Acute Anterior Uveitis. Brodie, James T. et al. Ophthalmology, Volume 131, Issue 11, 1281 – 1289.

People regularly deal with seasonal allergies, but how much do these environmental factors affect our corneas? Dr. Matt Feng sits down with Dr. Laura Downie to discuss her recent Ophthalmology article, “Intravital Imaging of the Human Cornea Reveals the Differential Effects of Season on Innate and Adaptive Immune Cell Morphodynamics.” Intravital Imaging of the Human Cornea Reveals the Differential Effects of Season on Innate and Adaptive Immune Cell Morphodynamics. Wu, Mengliang et al. Ophthalmology, Volume 131, Issue 10, 1185 – 1195

Why is peer review important? Is AI changing peer review? How can you become a better peer reviewer? Find out in this special episode, with our newest host and Social Media Editor, Dr. Emily Schehlein, and Dr. Matilda F. Chan. Dr. Chan, in collaboration with editors of several ophthalmic and optometric journals and the National Eye Institute, administers the new Council of Vision Editors Fellow Program designed to train early career vision scientists on the peer-review process. The Academy's family of journals is a proud participant in the mentoring program. For more, read Dr. Chan's editorial in Investigative Ophthalmology & Visual Science, “Peer Review in Ophthalmology: A Collaborative Approach to Training the Next Generation of Reviewers.”

Dr. Drew Carey interviews Dr. John J. Chen on the trends and use patterns of plasma exchange therapy for optic neuritis, from his Ophthalmology article, “Trends in Plasma Exchange Use in Optic Neuritis Hospitalizations in the United States.” Trends in Plasma Exchange Use in Optic Neuritis Hospitalizations in the United States. Akosman, Sinan et al. Ophthalmology, Volume 131, Issue 10, 1207 – 1214.

Dr. Rajesh Rao speaks with Dr. Jasmine H. Francis on whether sequencing of plasma-derived ctDNA can noninvasively diagnose ocular-involving histiocytosis. From her Ophthalmology Science article, “Plasma-Derived Cell-Free DNA for the Diagnosis of Ocular-Involving Histiocytosis.” Plasma-Derived Cell-Free DNA for the Diagnosis of Ocular-Involving Histiocytosis. Francis, Jasmine H. et al. Ophthalmology Science, Volume 4, Issue 5.

Can artificial intelligence distinguish between pseudopapilledema and true papilledema in children? Dr. Drew Carey interviews author Dr. Melinda Y. Chang on whether AI can be used to improve the diagnostic process in children with abnormal optic nerves and concern for elevated intracranial pressure. From her Ophthalmology Science article, “Artificial Intelligence to Differentiate Pediatric Pseudopapilledema and True Papilledema on Fundus Photographs” Artificial Intelligence to Differentiate Pediatric Pseudopapilledema and True Papilledema on Fundus Photographs. Chang, Melinda Y. et al. Ophthalmology Science, Volume 4, Issue 4.

Does primary trabeculectomy or medical treatment produce better outcomes in terms of quality of life, clinical effectiveness, and safety in patients with advanced glaucoma? Dr. Drew Carey interviews Dr. Anthony J. King on the results of his recent study asking this question published in Ophthalmology, “Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study.” Evaluating Primary Treatment for People with Advanced Glaucoma. King, Anthony J. King, Anthony et al. Ophthalmology, Volume 131, Issue 7, 759 – 770. Join Ophthalmology's Editor-in-Chief, Russell Van Gelder, as he presents “The Year in Literature: Editor's Choice Highlights From the Ophthalmology Journal Family”  in Chicago at AAO 2024 on Sunday October 20, 2024, at 2pm local time in McCormick Place South Building Room S406A. Search “SYM48” in the Mobile Meeting Guide for more information.

How has ophthalmology medical education changed over time in medical school curriculums? Dr. Edmund Tsui speaks with Drs. Ashish Agar and Sascha Spencer on their review of global trends in medical school ophthalmology education from their Ophthalmology article, “A Systematic Review of Ophthalmology Education in Medical Schools: The Global Decline.” A Systematic Review of Ophthalmology Education in Medical Schools. Spencer, Sascha K.R. et al. Ophthalmology, Volume 131, Issue 7, 855 – 863. Join Ophthalmology's Editor-in-Chief, Russell Van Gelder, as he presents “The Year in Literature: Editor's Choice Highlights From the Ophthalmology Journal Family”  in Chicago at AAO 2024 on Sunday October 20, 2024, at 2pm local time in McCormick Place South Building Room S406A. Search “SYM48” in the Mobile Meeting Guide for more information.

Ophthalmologists are not spared from the opioid epidemic. Recent studies have shown that opioids continue to be prescribed after ophthalmic surgeries. Dr. Drew Carey interviews Dr. Matthew R. Starr on his retrospective study published in Ophthalmology, “Hospitalization, Overdose, and Mortality After Opioid Prescriptions Tied to Ophthalmic Surgery.” Hospitalization, Overdose, and Mortality After Opioid Prescriptions Tied to Ophthalmic Surgery. Thao, Viengneesee et al. Ophthalmology, Volume 131, Issue 8, 943 – 949. Join Ophthalmology's Editor-in-Chief, Russell Van Gelder, as he presents “The Year in Literature: Editor's Choice Highlights From the Ophthalmology Journal Family”  in Chicago at AAO 2024 on Sunday October 20, 2024, at 2pm local time in McCormick Place South Building Room S406A. Search “SYM48” in the Mobile Meeting Guide for more information.

The RID-MyC assay, a CRISPR/Cas12a-based test, offers swift and reliable detection of Fungal Keratitis, enhancing diagnostic capabilities at point-of-care settings. Dr. Rajesh Rao interviews Dr. Siddharth Narendran on the development of this assay from his Ophthalmology Science article, “Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid Detection Platform for the Diagnosis of Keratomycoses.” Development and Clinical Evaluation of a CRISPR/Cas12a-Based Nucleic Acid Detection Platform for the Diagnosis of Keratomycoses. Deivarajan, Hanith Raj et al. Ophthalmology Science, Volume 4, Issue 5. Join Ophthalmology's Editor-in-Chief, Russell Van Gelder, as he presents “The Year in Literature: Editor's Choice Highlights From the Ophthalmology Journal Family”  in Chicago at AAO 2024 on Sunday October 20, 2024, at 2pm local time in McCormick Place South Building Room S406A. Search “SYM48” in the Mobile Meeting Guide for more information.

Dr. Matt Feng is joined by Dr. Thomas H. Dohlman to discuss the effectiveness of topical and subconjunctival bevacizumab in suppressing vascularization in graft and host bed after high-risk corneal transplantation, from his Ophthalmology Science article “Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation” Suppression of Neovascularization by Topical and Subconjunctival Bevacizumab After High-Risk Corneal Transplantation. Dohlman, Thomas H. et al. Ophthalmology Science, Volume 4, Issue 4.

What does hearing dysfunction have to do with an ophthalmology podcast? Listen up and find out as Dr. Drew Carey interviews Dr. Jamie A. Keen and Dr. Erin M. Shriver on the risks of using teprotumumab to hearing function in treatment of thyroid eye disease. From their article “Frequency and Patterns of Hearing Dysfunction in Patients Treated with Teprotumumab.” Frequency and Patterns of Hearing Dysfunction in Patients Treated with Teprotumumab. Keen, Jamie A. et al. Ophthalmology, Volume 131, Issue 1, 30 – 36.

Dr. Matt Feng interviews Drs. Bita Momenaei and Jason Hsu on the incidence, timing, risk factors, and outcomes of recurrent retinal detachment after phacoemulsification, from their Ophthalmology Retina article, “Incidence and Outcomes of Recurrent Retinal Detachment after Cataract Surgery in Eyes with Prior Retinal Detachment Repair.” Incidence and Outcomes of Recurrent Retinal Detachment after Cataract Surgery in Eyes with Prior Retinal Detachment Repair. Momenaei, Bita et al. Ophthalmology Retina, Volume 8, Issue 5, 447 - 455.

Private equity (PE) firms acquired over 200 ophthalmology and optometry practices in the United States from 2021 through 2019. Dr. Rajesh Rao interviews author Dr. Gary Joseph Lelli about the implications of this trend and influence of PEs on care use and spending, from his Ophthalmology article, “Association of Private Equity Firm Acquisition of Ophthalmology Practices with Medicare Spending and Use of Ophthalmology Services.” Association of Private Equity Firm Acquisition of Ophthalmology Practices with Medicare Spending and Use of Ophthalmology Services. Braun, Robert Tyler et al. Ophthalmology, Volume 131, Issue 3, 360 – 369.

X-linked retinoschisis is a relatively common inherited retinal degenerative disease that almost exclusively affects males. No curative medical therapy is available for this condition, however topical and oral carbonic anhydrase inhibitors have been used  for the management of cystoid fluid collections. Dr. Drew Carey interviews authors Dr. Jonathan Hensman and Dr. Camiel J.F. Boon on the results of their Ophthalmology Retina article, “Efficacy of Carbonic Anhydrase Inhibitors on Cystoid Fluid Collections and Visual Acuity in Patients with X-Linked Retinoschisis.” Efficacy of Carbonic Anhydrase Inhibitors on Cystoid Fluid Collections and Visual Acuity in Patients with X-Linked Retinoschisis. Hensman, Jonathan et al. Ophthalmology Retina. In press The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more! Sign up for the next Ophthalmology Journal Virtual Club on June 19, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Uveitis is a heterogenous group of inflammatory eye diseases for which current cytokine-targeted immune therapies are effective for only a subset of patients. Dr. Edmund Tsui is joined by Dr. Lynn M. Hassman and MD/PhD student Joseph B. Lin to explore potential common underlying mechanisms that exist for immune cell recruitment in uveitis in their Ophthalmology Science article, “Aqueous macrophages contribute to conserved CCL2 and CXCL10 gradients in uveitis” Aqueous Macrophages Contribute to Conserved CCL2 and CXCL10 Gradients in Uveitis. Lin, Joseph B. et al. Ophthalmology Science, Volume 4, Issue 4. The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more! Sign up for the next Ophthalmology Journal Virtual Club on June 19, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Vitamin A deficiency is the leading cause of preventable childhood blindness worldwide, but how does this deficiency present itself in a clinical setting? Dr. Drew Carey finds out as he interviews Dr. Nieraj Jain, author of “Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Referral Center in the United States.” Characteristics of Vitamin A Deficiency Retinopathy at a Tertiary Referral Center in the United States. Levine, David A. et al. Ophthalmology Retina, Volume 8, Issue 2, 126 - 136 The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

An analysis of the IRIS® Registry shows IOL exchanges are increasing over time with vision improving 60% of the time, but worse visual outcomes associated with greater age, worse baseline vision, Black race, Hispanic ethnicity, Medicaid insurance, smoking, and concurrent vitrectomy. Dr. Matt Feng sits with authors Drs. David F. Chang and Fasika A. Woreta to discuss these findings and more from their Ophthalmology article, “Visual Acuity Outcomes and Complications after Intraocular Lens Exchange: An IRIS® Registry (Intelligent Research in Sight) Analysis.” Visual Acuity Outcomes and Complications after Intraocular Lens Exchange. Son, Hyeck-Soo et al. Ophthalmology, Volume 131, Issue 4, 403 – 411. The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

The Department of Health and Human Services, Health Resources and Services Administration's Health Workforce Simulation Model forecasts a sizeable shortage of ophthalmology supply relative to demand by the year 2035, with substantial geographic disparities. Dr. Edmund Tsui is here with author Dr. Sean T. Berkowitz to breakdown the implications of this shortage from his recent Ophthalmology article, Ophthalmology Workforce Projections in the United States, 2020 to 2035. Ophthalmology Workforce Projections in the United States, 2020 to 2035. Berkowitz, Sean T. et al. Ophthalmology, Volume 131, Issue 2, 133 – 139. The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

Scleral buckling is a common surgical procedure for the repair of rhegmatogenous retinal detachment. The association between scleral buckling and angle-closure glaucoma is well-documented. However,the influence of scleral buckling on the development and progression of open-angle glaucoma is less well understood. Dr. Lori Provencher interviews Dr. Arthur J. Sit on the effect of scleral buckle surgery on ocular biomechanics and aqueous humor dynamics from his Ophthalmology Glaucoma article, “The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics.” The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics. Lyons, Lance J. et al. Ophthalmology Glaucoma, Volume 7, Issue 1, 1 – 7. The Ophthalmology-family of journals is now on Instagram. Follow @aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

Neuro-ophthalmology consultations are critical to the diagnosis and management in the hospital setting. Prompt consultation prevents diagnostic errors and improves patient outcomes. The scarcity of neuro-ophthalmologists means that the increasing outpatient demand cannot be met, prompting many emergency department referrals by non–neuro-ophthalmologists. Dr. Drew Carey discusses this shortage of neuro-ophthalmologists and the need for technological and diagnostic aids for greater outpatient access with Dr. Valérie Biousse, author of “Neuro-ophthalmology Emergency Department and Inpatient Consultations at a Large Academic Referral Center.” Neuro-ophthalmology Emergency Department and Inpatient Consultations at a Large Academic Referral Center. Okrent Smolar, Avital Lily et al. Ophthalmology, Volume 130, Issue 12, 1304 – 1312

Syphilis is often known as the “the great masquerader” because it can mimic symptoms and look like a wide array of other diseases. Dr. Edmund Tsui interviews Dr. Michael Huvard to get to the bottom of how acute syphilitic posterior placoid chorioretinopathy presents itself in eyes and the outcomes for these patients, from his Ophthalmology article “Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy” Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy. Mirzania, Delaram et al. Ophthalmology Retina, Volume 7, Issue 12, 1080 - 1086 Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Dr. Drew Carey sits down with Dr. Thomas V. Johnson to discuss the work of the RReSTORe Consortium in the field of regenerative medicine as applied to optic neuropathies from his Ophthalmology Science article, “The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, & Optic Nerve Regeneration (RReSTORe) Consortium.” For more of the Ophthalmology Science special issue on Neuroprotection, Neuroenhancement, and Neuroregeneration visit https://www.ophthalmologyscience.org/xops-vsi-neuroprotection For more information on the RReSTORe Consortium visit: https://www.johnsonlab.co/rrestore-home/rrestore-main-page/ The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration Consortium. Johnson, Thomas V. et al. Ophthalmology Science, Volume 3, Issue 4. Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Endothelial keratoplasty (EK) procedures have become the preferred method of corneal transplantation in the United States. As the frequency of EKs increase, so do associated costs. Dr. Matt Feng interviews Drs. David S. Portney and Shahzad I. Mian about their recent analysis to assess for differences in surgical costs and surgery length based on type of EK, use of preloaded grafts, and performance of simultaneous cataract surgery with EK from their Ophthalmology article “Cost Drivers of Endothelial Keratoplasty: A Time-Driven Activity-Based Costing Analysis.” Cost Drivers of Endothelial Keratoplasty. Goldstein, Jenna K. et al. Ophthalmology, Volume 130, Issue 10, 1073 – 1079. Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

The Primary Tube Versus Trabeculectomy Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery and trabeculectomy with mitomycin C in eyes without previous ocular surgery. Dr. Lori Provencher sits down with authors Dr. Sara J. Coulon and Dr. Steven J. Gedde to discuss the results of this trail from their Ophthalmology Glaucoma article, “Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study.” Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study. Coulon, Sara J.Gedde, Steven J. et al. Ophthalmology Glaucoma, Volume 6, Issue 4, 422 – 431.

Myelin oligodendrocyte glycoprotein-related optic neuritis is typically associated with good visual outcome in most patients, but poor outcomes are reported in 15% to 36.8% of patients. Dr. Drew Carey sits down with Dr. Edward Margolin to discuss the possible factors associated with poor outcomes, from his Ophthalmology article, “Predictors of Poor Visual Outcome in MOG-related Optic Neuritis.” Predictors of Poor Visual Outcome in Myelin Oligodendrocyte Glycoprotein-Related Optic Neuritis. Handzic, Armin et al. Ophthalmology, Volume 130, Issue 9, 993 - 995

Recorded live at AAO 2023 and we're myth busting common ophthalmologic misconceptions of the anterior segment. Drs. Drew Carey and Matt Feng interview Dr. Todd Margolis on his recent Ophthalmology editorial, “Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology.” He shares bonus myths not in the editorial, and takes questions from the audience. (Producer's note: Please excuse the audio quality. This episode was recorded on the convention center floor using an iPhone.) Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Margolis, Todd P. & Galor, Anat. Ophthalmology, Volume 130, Issue 8, 783 – 785.

One-third of US ophthalmologists left at least one practice from 2014-2021. What are the factors behind this high turnover rate, how does this affect patient care, and what can be done to stabilize the workforce? Dr. Rajesh Rao interviews Dr. Ravi Parikh about his Ophthalmology article, “Ophthalmologist Turnover in the United States: Analysis of Workforce Changes from 2014 through 2021.” Ophthalmologist Turnover in the United States. Patel, Prem N. et al. Ophthalmology, Volume 130, Issue 9, 973 – 981.

What treatments are effective for uveitic macular edema? Drs. Nisha R. Acharya and Douglas A. Jabs of the MUST Research Group discuss with Dr. Edmund Tsui the landmark findings of the MERIT Trial in their recent Ophthalmology article, “Intravitreal Therapy for Uveitic Macular Edema—Ranibizumab versus Methotrexate versus the Dexamethasone Implant.” Intravitreal Therapy for Uveitic Macular Edema—Ranibizumab versus Methotrexate versus the Dexamethasone Implant. Acharya, Nisha R. et al. Ophthalmology, Volume 130, Issue 9, 914 - 923

News broke in early 2023 of several deaths related to use of contaminated over-the-counter artificial tear products resulting in FDA and CDC warnings and a product recall. Dr. Matt Feng reviews what transpired and discusses lessons learned with Dr. Gary Novack, author of the Ophthalmology editorial, “Infections from Over-The-Counter Artificial Tears: Implications for Patients and Clinicians.” Infections from Over-the-Counter Artificial Tears: Implications for Patients and Clinicians. Novack, Gary D. Ophthalmology, Volume 130, Issue 11, 1114 - 1117 Join us in San Francisco at AAO 2023 for a live recording of our podcast on Saturday November 4, 2023, at 3:30pm local time at the Showcase Theater, Booth #5302, in Moscone Center North. Our hosts will interview Dr. Todd Margolis on his recent editorial, Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Use the Adjunct Event Search for ISC10 in the Mobile Meeting Guide for more information.

Cataract surgery is one of the most commonly performed surgeries globally. What are the risk factors for patients developing pseudophakic cystoid macular edema after cataract surgery? Dr. Edmund Tsui sits down with Dr. Ahmed B. Sallam to discuss the findings of his Ophthalmology article, “Risk of Pseudophakic Cystoid Macular Edema in Fellow-Eye Cataract Surgeries: A Multicenter Database Study.” Risk of Pseudophakic Cystoid Macular Edema in Fellow-Eye Cataract Surgeries. Shakarchi, Ahmed F. et al. Ophthalmology, Volume 130, Issue 6, 640 - 645 Join us in San Francisco at AAO 2023 for a live recording of our podcast on Saturday November 4, 2023, at 3:30pm local time at the Showcase Theater, Booth #5302, in Moscone Center North. Our hosts will interview Dr. Todd Margolis on his recent editorial, Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Use the Adjunct Event Search for ISC10 in the Mobile Meeting Guide for more information.

Does multiple sclerosis contribute to the degeneration of the outer retinal layers? Dr. Drew Carey interviews Dr. Imre Lengyel on his recent Ophthalmology Science article, “Reduced Cone Density Is Associated with Multiple Sclerosis.” Reduced Cone Density Is Associated with Multiple Sclerosis. McIlwaine, Gemma et al. Ophthalmology Science, Volume 3, Issue 3, 100308 Sign up for the next Ophthalmology Journal Virtual Club on October 12, 2023, at https://store.aao.org/ophthalmology-virtual-journal-club.html Join us in San Francisco at AAO 2023 for a live recording of our podcast on Saturday November 4, 2023, at 3:30pm local time at the Showcase Theater, Booth #5302, in Moscone Center North. Our hosts will interview Dr. Todd Margolis on his recent editorial, Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Use the Adjunct Event Search for ISC10 in the Mobile Meeting Guide for more information.

How can we improve the design and reporting of ophthalmic randomized controlled trials? Dr. Edmund Tsui discusses this with Dr. Gui-shuang Ying author of Ophthalmology Science's “Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials.” Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials. Dong, Ruiqi et al. Ophthalmology Science, Volume 3, Issue 2, 100266. Sign up for the next Ophthalmology Journal Virtual Club on October 12, 2023, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Can ChatGPT pass the OKAP exam? Dr. Matt Feng interviews author Dr. Fares Antaki about the implications of using a language model artificial intelligence in ophthalmology from his Ophthalmology Science article, “Evaluating the Performance of ChatGPT in Ophthalmology: An Analysis of Its Successes and Shortcomings” Evaluating the Performance of ChatGPT in Ophthalmology. Antaki, Fares et al. Ophthalmology Science. In press. Sign up for the next Ophthalmology Journal Virtual Club on October 12, 2023, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Is an eye stroke (CRAO) the same as a brain stroke? What new treatments are available for eye stroke? Dr. Drew Carey sits down with Drs. Aubrey Gilbert and Robin Vora to discuss their Ophthalmology Retina article, Central Retinal Artery Occlusion: Time to Presentation and Diagnosis.  Central Retinal Artery Occlusion. Shah, Ronak et al. Ophthalmology Retina, Volume 7, Issue 6, 527 - 531 Sign up for the next Ophthalmology Journal Virtual Club on October 12 at https://store.aao.org/ophthalmology-virtual-journal-club.html

Primary angle-closure glaucoma is a leading cause of vision loss, affecting an estimated 20 million people. Dr. Lori Provencher sits down with Dr. Benjamin Xu to discuss the research from his article, “Rates and Patterns of Diagnostic Conversion from Anatomical Narrow Angle to Primary Angle-Closure Glaucoma in the United States.” Rates and Patterns of Diagnostic Conversion from Anatomical Narrow Angle to Primary Angle-Closure Glaucoma in the United States. Yoo, Kristy et al. Ophthalmology Glaucoma, Volume 6, Issue 2, 169 - 176

Dr. Matt Feng interviews Drs. Koji Kitazawa and Shigeru Kinoshita about their research on endothelial cell loss after corneal transplantation from their Ophthalmology Science article, “The Biologic Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation.” The Biologic Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation Kitazawa, Koji et al. Ophthalmology Science, Volume 3, Issue 2, 100239

Dr. Lorraine Provencher interviews Dr. Kaweh Mansouri about the results of his study using EYEMATE-SC sensor to monitor IOP measurements in glaucoma patients. From Ophthalmology's “EYEMATE-SC Trial: Twelve-Month Safety, Performance, and Accuracy of a Suprachoroidal Sensor for Telemetric Measurement of Intraocular Pressure” EYEMATE-SC Trial: Twelve-Month Safety, Performance, and Accuracy of a Suprachoroidal Sensor for Telemetric Measurement of Intraocular Pressure. Szurman, PeterSzurman, Peter et al. Ophthalmology, Volume 130, Issue 3, 304 - 312

In the US, health care is responsible for approximately 8.5% of greenhouse gas. How can we reduce the impact of cataract surgery on our environment? Dr. Edmund Tsui discusses this with Dr. Joel S. Schuman and Dr. Cassandra L. Thiel, authors of “How Ophthalmologists Can Decarbonize Eye Care: A Review of Existing Sustainability Strategies and Steps Ophthalmologists Can Take.” How Ophthalmologists Can Decarbonize Eye Care. Sherry, Brooke et al. Ophthalmology, Volume 130, Issue 7, 702 - 714

What's the risk of contracting Acanthamoeba keratitis with daily disposable contact lenses compared with daily wear reusable lenses? Dr. Edmund Tsui explores this with Dr. John Dart, author of “Acanthamoeba Keratitis Risk Factors for Daily Wear Contact Lens Users.”  Acanthamoeba Keratitis Risk Factors for Daily Wear Contact Lens Users. Carnt, Nicole et al. Ophthalmology, Volume 130, Issue 1, 48 – 55.

In this episode, Dr. Drew Carey interviews Dr. Aaron Nagiel about his recent case series on benign intraretinal tumors and the coining of the term “benign lobular inner nuclear layer proliferation” aka BLIPs. From Ophthalmology's “Benign Lobular Inner Nuclear Layer Proliferations of the Retina Associated with Congenital Hypertrophy of the Retinal Pigment Epithelium” Benign Lobular Inner Nuclear Layer Proliferations of the Retina Associated with Congenital Hypertrophy of the Retinal Pigment Epithelium. Sanfilippo, Christian J. et al. Ophthalmology, Volume 130, Issue 3, 265 - 273 Please tell us what you think of our show in a brief 2-minute survey: https://forms.office.com/r/B4rYtvpQad

Telehealth has become more accessible since the COVID-19 pandemic. But how easily do patients take to home testing and what is the acceptability and feasibility home monitoring of glaucoma? Dr. Lori Provencher discusses this with Dr. Lama A. Al-Aswad, author of “Home Monitoring of Glaucoma Using a Home Tonometer and a Novel Virtual Reality Visual Field Device.” Home Monitoring of Glaucoma Using a Home Tonometer and a Novel Virtual Reality Visual Field Device. Hu, Galen Y. et al. Ophthalmology Glaucoma, Volume 6, Issue 2, 121 – 128. Please tell us what you think of our show in a brief 2-minute survey: https://forms.office.com/r/B4rYtvpQad