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20 episodes with neuroprotection
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2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
9 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
7 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
2 episodes with neuroprotection
In this episode, Nurse Doza explores The Master Antioxidant: 5 Ways Glutathione Supports Your Health. Learn how glutathione impacts liver detoxification, brain health, inflammation reduction, hormone balance, and chronic disease prevention. Discover practical ways to boost glutathione naturally and why it's essential for optimal energy, longevity, and overall wellness. 5 KEY TAKEAWAYS Liver Health Support: Glutathione is critical for liver detoxification and reversing fatty liver disease. Brain Function Boost: Low glutathione levels are linked to cognitive decline, Alzheimer's, and Parkinson's. Inflammation Reduction: Glutathione neutralizes oxidative stress, reducing chronic inflammation throughout the body. Hormone Balance: Proper glutathione levels help regulate estrogen metabolism and reduce breast cancer risk. Disease Prevention: Every chronic disease is linked to glutathione deficiency—raising levels improves resilience and recovery. FEATURED PRODUCT Boost by MSW Nutrition features glutathione alongside a powerful multivitamin blend, helping your body detoxify, fight inflammation, and improve energy naturally. Whether you're focused on reversing fatty liver, supporting brain health, or reducing inflammation, Boost delivers the master antioxidant directly to your system—keeping you energized and protected every day.
On this episode of The Vitamin Professor Podcast, Professor Gene Bruno talks to Gad Gilad, Co-Founder & CEO at Gilad&Gilad LLC.This podcast is brought to you in partnership with VRM Media and Nutraland USA, Inc. For more information about our host and guest, please see the below information.https://fornervehealth.com/https://fornervehealth.com/research/#Agmatinenutriscienceusa.comhttps://www.linkedin.com/in/gad-m-gilad-ph-d-49900323/https://www.linkedin.com/in/dr-gene-bruno-dbm-ms-rh-ahg-2ab0508/www.vrmmedia.com@hnvirtual, #hnvirtual, #gadgilad, #fornervehealth #genebruno, #thevitaminprofessorFind our podcast on your favorite platform:podcasts.apple.com/us/podcast/the-vitamin-professor-podcast/id1746137375youtube.com/channel/UCxeQ-IuqCRmq0YLc7jQNMKAmusic.amazon.com/podcasts/a8a96593-b93c-48cf-9fe9-2891c4035dad/the-vitamin-professor-podcastiheart.com/podcast/269-the-vitamin-professor-podc-175888136/
Join longevity experts Chris Burres and Lisa Tamati as they dive into cutting-edge biohacking strategies to optimise health and extend lifespan. In this engaging live session, they explore hydrogen inhalation for reducing oxidative stress, hyperbaric oxygen therapy (HBOT) for healing and neuroprotection, and the power of exogenous ketones in supporting brain health and cancer recovery. Lisa shares her inspiring journey of saving her mother's life through relentless research and a fighter's mindset, while Chris introduces innovative tools like nano oxygen therapy and ESR testing. Packed with actionable insights, this episode is a must-watch for anyone passionate about longevity, health optimization, and biohacking. Tune in monthly for more groundbreaking discussions! Connect with Chris Burres: Website: www.myvitalc.com YouTube: www.youtube.com/@myvitalc Instagram: @myvitalc
Clinical Pearls from Dr. Dominic D'Agostino: Therapeutic Strategies and Clinical Success with the Ketogenic Diet For this week's episode of the Clinician's Corner, we're doing something differently. We have gone into the archives and pulled out clinical pearls from some of our favorite episodes, and we're starting today with one of our most popular interviews with Dr. Dominic D'Agostino - where we unpack the ketogenic diet in all its nuances. This interview first aired back in 2023, and the full interview can be viewed here. Clinical pearls we extracted from the original interview: When the ketogenic diet is best used clinically; when it's contraindicated; and how to structure it for best results What the latest research is telling us about therapeutic application of this protocol - from metabolic health to neurological considerations and cancer Exogenous ketones: when and how to use them The intricacies of macronutrient ratios and when/how to cycle in and out of ketosis Measurement: the best forms for tracking ketosis and other key biomarkers to monitor The Clinician's Corner is brought to you by Restorative Wellness Solutions. Follow us: https://www.instagram.com/restorativewellnesssolutions/ Connect with Dr. D'Agostino: Website: https://drdominicdagostino.com/ Instagram: https://www.instagram.com/dominic.dagostino.kt/ LinkedIn: https://www.linkedin.com/in/dominic-d-agostino-156014b/ Twitter: https://twitter.com/DominicDAgosti2 Learn more about the ketogenic diet here: https://ketonutrition.org/ Timestamps: 00:00 History and Uses of Ketogenic Diet 06:25 Liver's Role in Ketone Production 07:22 Preventing Kidney Stones on Keto 13:15 Ketogenic Diet Supplement Tips 14:58 Minimal Supplements for Ketogenic Diet 18:07 Misleading Marketing of 1,3-Butanediol 24:08 Advanced Hormone and Metabolomics Testing 27:20 Monitor Meds During Diet Changes Speaker bio: Dr. D'Agostino is a tenured Associate Professor at the University of South Florida (USF) Morsani College of Medicine in the Department of Molecular Pharmacology and Physiology. He teaches medical neuroscience, medical physiology, nutrition and neuropharmacology. He is also a Research Scientist at the Institute for Human and Machine Cognition (IHMC) to assist with their efforts towards optimizing the safety, health and resilience of the warfighter and astronaut. His primary research focuses on developing and testing nutritional and metabolic-based therapies for a variety of disease states and advancing the use of metabolic-based therapies into human clinical applications. Keywords: ketogenic diet, therapeutic ketosis, blood ketone levels, exogenous ketones, metabolic therapies, epilepsy, neuroprotection, anti-seizure strategy, type 2 diabetes, weight loss, cancer, muscle wasting, Parkinson's disease, Alzheimer's disease, migraines, polycystic ovary syndrome, psychiatric disorders, bipolar disorder, anxiety, autism, traumatic brain injury, non-alcoholic fatty liver disease, stroke, GLUT1 deficiency, carnitine supplementation, kidney stones, electrolyte balance, MCT oil, creatine monohydrate, caffeine and ketone production, comprehensive blood work Disclaimer: The views expressed in the RWS Clinician's Corner series are those of the individual speakers and interviewees, and do not necessarily reflect the views of Restorative Wellness Solutions, LLC. Restorative Wellness Solutions, LLC does not specifically endorse or approve of any of the information or opinions expressed in the RWS Clinician's Corner series. The information and opinions expressed in the RWS Clinician's Corner series are for educational purposes only and should not be construed as medical advice. If you have any medical concerns, please consult with a qualified healthcare professional. Restorative Wellness Solutions, LLC is not liable for any damages or injuries that may result from the use of the information or opinions expressed in the RWS Clinician's Corner series. By viewing or listening to this information, you agree to hold Restorative Wellness Solutions, LLC harmless from any and all claims, demands, and causes of action arising out of or in connection with your participation. Thank you for your understanding.
Dr. Emily Schehlein discusses recent guidelines from the American Glaucoma Society and the American Academy of Ophthalmology on Nicotinamide use for glaucoma neuroprotection with lead author, Dr. Aakriti Garg Shukla. Published in Ophthalmology Glaucoma, “American Glaucoma Society-American Academy of Ophthalmology Position Statement on Nicotinamide Use for Glaucoma Neuroprotection” American Glaucoma Society-American Academy of Ophthalmology Position Statement on Nicotinamide Use for Glaucoma Neuroprotection. Shukla, Aakriti Garg; Cioffi, George A.; John, Simon W.M; Wang, Qing; Liebmann, Jeffrey M. et al. Ophthalmology Glaucoma, Volume 8, Issue 2, 112 – 116. Sign up for the next Ophthalmology Journal Virtual Club on August 27, 2025, at https://store.aao.org/ophthalmology-virtual-journal-club.html
Nutrition Nugget! Bite-size bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Rutin, a powerful plant pigment that could transform your health with its antioxidant punch. It is found in foods like apples and buckwheat, so it teams up with vitamin C for surprising benefits. How might this little-known nutrient boost your brain, heart, blood pressure and more? What's one food you already eat that could be packing this hidden benefit? Tune in to find out! Like what you're hearing? Be sure to check out the full-length episodes of new releases every Wednesday. Have an idea for a nutrition nugget? Submit it here: https://asaladwithasideoffries.com/index.php/contact/ RESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramNutrition Nugget: Quercetin
In this special solo episode, it's just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I'm shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties. What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00 Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That's crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
In this large real-world study
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Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/Download The Bioregulator Cheat Sheet: https://bioregulatorcheatsheet.carrd.co/
Nutrition Nugget! Bite-size bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about methylene blue—yes, that bright blue liquid you've seen turning water (and lips!) a shocking shade of blue. But beyond its eye-catching color, could this synthetic compound hold the key to boosting brain function, fighting aging, and enhancing physical performance? Some biohackers swear by it, while others urge caution. So, what exactly is methylene blue, and is it the next big thing in wellness—or just another fleeting trend? Tune in to find out! Like what you're hearing? Be sure to check out the full-length episodes of new releases every Wednesday. Have an idea for a nutrition nugget? Submit it here: https://asaladwithasideoffries.com/index.php/contact/ RESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramNutrition Nugget: Red Light Therapy
What if a simple molecule could revolutionize health and longevity?n this Salad with a Side of Fries episode, Jenn Trepeck welcomes Greg the Hydrogen Man, a molecular hydrogen therapy specialist, researcher, and the voice behind the popular YouTube channel Uprising 144k. Greg shares his journey of overcoming severe health challenges through molecular hydrogen and how this powerful antioxidant can optimize cellular health, reduce oxidative stress, and support overall well-being. From uncovering groundbreaking research in Japan to witnessing his father's recovery from arthritis, Greg dives deep into the science and potential of hydrogen therapy. He also sheds light on common misconceptions, warning about low-quality hydrogen products that may do more harm than good. The Salad With a Side of Fries podcast is hosted by Jenn Trepeck, discussing wellness and weight loss for real life, clearing up the myths, misinformation, bad science & marketing surrounding our nutrition knowledge and the food industry. Let's dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store. IN THIS EPISODE: (05:13) Greg shares his healing journey using molecular hydrogen (14:10) How Japan has integrated hydrogen therapy into medical practice(18:55) Greg shares his father's story of recovery from arthritis(27:00) Greg talks about the continuing research of molecular hydrogen (34:57) How does hydrogen create these positive results in cellular health(42:52) Quality is keyKEY TAKEAWAYS: Greg shares his journey of overcoming severe health challenges by incorporating molecular hydrogen into his routine. He warns about misleading hydrogen products, particularly hydrogen tablets, which may contain harmful compounds and alter water's pH in undesirable ways.Despite promising results and increasing research, molecular hydrogen therapy remains relatively unknown in mainstream healthcare. Greg noted that Japan has integrated hydrogen therapy into medical practice, while in the U.S., financial interests and misinformation may be slowing its adoption. Hydrogen is significantly smaller than other antioxidants, allowing it to reach deep into the mitochondria and every part of the body where other antioxidants cannot. This makes it particularly effective in combating oxidative stress linked to inflammation and various diseases.QUOTES:(11:08) “It's important to use hydrogen properly because it needs to be safe, but you want it to be effective. So we want it to work.” Greg the Hydrogen Man(21:41) “We don't realize the value of our health until it's jeopardized. Right? And then we realize how little these other things matter.” Jenn Trepeck(36:27) “They put hydrogen there because they had already seen that it was having a positive effect on all these medical conditions.” Greg the Hydrogen Man(37:26) “Inflammation is essentially the source of all sickness, illness, disease. It is oxidative stress, like the rusting of our insides.” Jenn Trepeck(40:04) “Hydrogen is the most abundant element.” Jenn Trepeck(48:51) “When we can increase the nutrient density and the way nutrients reach the different body parts, there's so much possibility.” Jenn TrepeckRESOURCES:Become A Member of Salad with a Side of FriesJenn's Free Menu PlanA Salad With a Side of FriesA Salad With A Side Of Fries MerchA Salad With a Side of Fries InstagramBiostack Over BiohackBecome a Member to Receive 10% Discount off H2 TabsNutrition Nugget: AntioxidantsWhat's Your Biological AgeGUEST RESOURCES:Uprising144K Hydrogen Man - PodcastGreg Hman - InstagramHoly Hydrogen Machine - WebsiteMy Pure Water - Carbon Distiller - WebsiteGUEST BIOGRAPHY: Greg the Hydrogen Man is a molecular hydrogen therapy specialist, researcher, and host of the popular YouTube channel Uprising144K. Struggling to find answers and overcome extreme depression due to his compromised immune system, tumors, autoimmune issues, gut problems, arthritis, wheelchair-bound immobility, and a severe heart condition, he began his journey to heal himself and discover hydrogen along the way. Studying the complex compound for four years, he implemented it into his health regimen and reversed his health challenges. Greg discusses the endless health benefits of hydrogen, how it helps protect against EMF radiation, topical application for skin problems, tumors, hormone support, COVID-19 and marketing tricks to watch out for when shopping for generators.
The blood-brain barrier (BBB)
Download Your Free Guide - 3 Things You Need to Know About Cancer: https://www.katiedeming.com/cancer-101/Are the healing properties of hydrogen real or just hype?With so many water options available today, it's hard to separate fact from fiction. Dr. Katie Deming speaks with Dr. Paul Barattiero, founder of Echo Water and an expert on hydrogen water's therapeutic properties. You'll discover how hydrogen water works in your body to reduce inflammation and oxidative stress—two major contributors to cancer and chronic disease. Dr. Barattiero explains the crucial differences between hydrogen water and alkaline water, debunking common myths that might be affecting your health decisions.Chapters:02:26 - Why is hydrogen water so popular? 04:38 - The real cause of chronic disease 15:14 - Does hydrogen water work without other treatments? 21:00 - The surprising link to brain health36:00 - How hydrogen water boosts fasting benefitsDr. Katie and Dr. Barattiero discuss the practical aspects too—how long hydrogen water stays effective, which products actually work, and how to incorporate hydrogen water into your daily routine including during therapeutic fasting. Listen and learn if hydrogen water complements conventional cancer treatments or interferes with them.Learn more about hydrogen water: https://echowater.com/Send us a text with your question (include your phone number)Transform your hydration with the system that delivers filtered, mineralized, and structured water all in one. Spring Aqua System: https://springaqua.info/drkatie Don't Face Cancer Alone"The 6 Pillars of Healing Cancer" workshop series provides you valuable insights and strategies to support your healing journey - Click Here to Enroll MORE FROM KATIE DEMING M.D. Free Guide - 3 Things You Need to Know About Cancer: https://www.katiedeming.com/cancer-101/6 Pillars of Healing Cancer Workshop Series - Click Here to EnrollWork with Dr. Katie: www.katiedeming.comFollow Dr. Katie Deming on Instagram: https://www.instagram.com/katiedemingmd/ Take a Deeper Dive into Your Healing Journey: Dr. Katie Deming's Linkedin Here Please Support the Show Share this episode with a friend or family member Give a Review on Spotify Give a Review on Apple Podcast DISCLAIMER:The Born to Heal Podcast is intended for informational purposes only and is not a substitute for seeking professional medical advice, diagnosis, or treatment. Individual medical histories are unique; therefore, this episode should not be used to diagnose, treat, cure, or prevent any disease without consulting your healthcare p...
In this episode of Unreasonable Health, Regan Archibald dives into the fascinating world of nicotine as a nootropic, discussing its cognitive benefits, potential downsides, and how to use it safely. He explores nicotine's role in dopamine stimulation, memory enhancement, and neuroprotection, even highlighting its potential in preventing neurodegenerative diseases and supporting long-haul COVID recovery. Regan also compares nicotine to peptides like Dihexa and Semax, offering alternatives for brain optimization. The episode challenges long-standing stigmas around nicotine while emphasizing safe sourcing, microdosing, and cycling strategies to avoid dependency. Tune in to discover whether nicotine could be a valuable tool in your cognitive enhancement toolbox.Want to work witih us for optimal brain function, longevity, and phenomenal energy? https://acueastwest.com/
More good news about Omega-3s for heart health; Addressing early-stage dementia; When Lyme Disease doesn't respond to antibiotics; Ultra-processed food hijacks brain within days; Exosomes and adaptive deep-brain stimulation offer hope for Parkinson's; Psychologists conclude relentless “pursuit of happiness” may exhaust our brains' control centers; A common over-the-counter drug taken in pregnancy may hike offsprings' risk of ADHD.
Today, we're diving deep into an important topic in the world of sports and beyond – concussions. Our host, Chris Duffin, welcomes guest Anthony Castor to explore the complexities of traumatic brain injuries, often caused by sudden jolts or blows to the head. The episode uncovers the neurological changes that these injuries entail, discussing both their short-term symptoms, like headaches and confusion, and long-term effects, including cognitive impairment and mood disorders. Moreover, Chris and Anthony delve into a variety of healing protocols, emphasizing the pivotal role of peptides in recovery. Whether you're an athlete or someone curious about brain health, this episode offers vital insights on tackling brain injuries and fostering resilience. Tune in and learn about strategies to not only manage but also prevent the implications of concussions.
Three recent trials investigated the effectiveness of endovascular treatment (EVT) in ischemic stroke. The OPENS-2 trial (Lancet 2025) found that normobaric hyperoxia combined with EVT improved 90-day functional outcomes for large-vessel occlusion stroke without increasing adverse events. The DISTAL trial (NEJM 2025) reported no significant benefit of EVT over medical therapy for medium/distal vessel occlusions and noted a higher risk of hemorrhage. Similarly, the ESCAPE-MeVO trial (NEJM 2025) found no improvement with EVT in medium-vessel occlusion stroke, alongside increased mortality and intracranial hemorrhage. Collectively, these findings suggest that EVT's benefits depend on vessel size and may be enhanced with adjunctive treatments like hyperoxia in specific cases.
In this episode, Regan Archibald dives deep into the world of brain-boosting peptides, nootropics, and biohacking strategies for cognitive enhancement. He explores the importance of cycling nootropics like Cmax, Selank, and NAD+ to prevent diminishing returns and optimize brain function. Regan highlights the role of intranasal glutathione and NAD+ in reducing oxidative stress, improving neuroprotection, and enhancing mitochondrial function. He also introduces cutting-edge peptides like FGL, which show promise in neuroregeneration and cognitive repair. To provide measurable insights into brain health, he discusses the upcoming integration of NeuroCatch technology at East West, allowing for real-time tracking of cognitive improvements. Listeners are challenged to incorporate brain-healthy foods like eggs, blueberries, and dark chocolate while experimenting with nootropics to enhance focus, memory, and overall mental clarity.
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/
Neuroprotection is just about pricey moonshot Alzheimer drugs; Green tea, melatonin, quercetin, aerobic exercise tackle brain inflammation; Glyphosate may contribute to Alzheimer's surge; Supplements to extend sleep; A popular social media influencer makes shady claims about blood pressure supplements; Diet can influence the prognosis of early ovarian cancer; Omega-3s slow biological aging; A natural antidote to hair graying.
Dr. Daniel Vitt, the CEO of Immunic Therapeutics, is taking a different approach to treating autoimmune diseases, focusing on neuroprotection, gut barrier restoration, and anti-inflammatory effects. These dual-mechanism small-molecule drugs are initially developed for multiple sclerosis and inflammatory bowel diseases. The lead candidate for MS aims to reduce relapses, slow disease progression, and help prevent reactivation of Epstein-Barr virus due to the antiviral properties of the oral drug. Daniel explains, "If you look back over the last 20 years, maybe even longer, you figure out that there have been limited improvements in treating big chronic indications like autoimmune diseases. Specifically, looking from the patient's point of view, there are a lot of things missing. So, there are a lot of indications that are untreatable or not sufficiently solving the medical need or a lack of convenience for use, for example. Another thing that is highly underestimated usually is the safety and tolerability of the drugs. And it's our mission to work on having better drugs with better safety and tolerability profiles to offer patients more convenient and easy-to-use therapies." "That is something currently not addressed by the drugs available for patients today. Therefore, our drug is making a difference because our mode of action is a dual mode of action. On the one hand, the molecule is a potent anti-inflammatory drug by inhibition of a protein called DHODH. Secondly, we also have our molecule, a very good activator of a protein called Nurr1. This is a neuroprotective factor and plays an important role in the different areas of the brain, directly in the neurons in the brain, but also in the environment of the brain. That is why we believe Nurr1 activation is a key step forward to treating patients and offering a better benefit for slowing down the disability." "This is because quality of life is one of the important parameters for judging whether a drug does its job or not. We need to address this more in our industry, and therefore, I agree that it's an important piece. And with gut wall repair, you're more on the side of ok, maybe we can fix the problem in general and the body returns to normal behavior. So, in a perfect world, in further clinical trials, we can see cases of patients who maybe flip back to healthy status or disease-free status or something like that, for example, in celiac disease or other GI indications." #ImmunicThera #MultipleSclerosis #MS #AutoimmuneDiseases #InflammatoryDiseases #EpsteinBarrVirus #UlcerativeColitis #IBD imux.com Download the transcript here
Dr. Daniel Vitt, the CEO of Immunic Therapeutics, is taking a different approach to treating autoimmune diseases, focusing on neuroprotection, gut barrier restoration, and anti-inflammatory effects. These dual-mechanism small-molecule drugs are initially developed for multiple sclerosis and inflammatory bowel diseases. The lead candidate for MS aims to reduce relapses, slow disease progression, and help prevent reactivation of Epstein-Barr virus due to the antiviral properties of the oral drug. Daniel explains, "If you look back over the last 20 years, maybe even longer, you figure out that there have been limited improvements in treating big chronic indications like autoimmune diseases. Specifically, looking from the patient's point of view, there are a lot of things missing. So, there are a lot of indications that are untreatable or not sufficiently solving the medical need or a lack of convenience for use, for example. Another thing that is highly underestimated usually is the safety and tolerability of the drugs. And it's our mission to work on having better drugs with better safety and tolerability profiles to offer patients more convenient and easy-to-use therapies." "That is something currently not addressed by the drugs available for patients today. Therefore, our drug is making a difference because our mode of action is a dual mode of action. On the one hand, the molecule is a potent anti-inflammatory drug by inhibition of a protein called DHODH. Secondly, we also have our molecule, a very good activator of a protein called Nurr1. This is a neuroprotective factor and plays an important role in the different areas of the brain, directly in the neurons in the brain, but also in the environment of the brain. That is why we believe Nurr1 activation is a key step forward to treating patients and offering a better benefit for slowing down the disability." "This is because quality of life is one of the important parameters for judging whether a drug does its job or not. We need to address this more in our industry, and therefore, I agree that it's an important piece. And with gut wall repair, you're more on the side of ok, maybe we can fix the problem in general and the body returns to normal behavior. So, in a perfect world, in further clinical trials, we can see cases of patients who maybe flip back to healthy status or disease-free status or something like that, for example, in celiac disease or other GI indications." #ImmunicThera #MultipleSclerosis #MS #AutoimmuneDiseases #InflammatoryDiseases #EpsteinBarrVirus #UlcerativeColitis #IBD imux.com Listen to the podcast here
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/
In today's episode, we will pick up where we left off last week during my "podcast" presentation of The Mitochondrial Triad lecture I gave last month in Rome. Undoubtedly, you are getting more nuggets of wisdom in this podcast version, as I am able to go down various rabbit holes and dig deeper into the details since there are no time constraints. For example, today's episode that is entirely on the topic of methylene blue is longer in duration than my entire presentation at the symposium in Rome. Last week, I covered the first two topics of my talk: mitochondria (i.e., why they are important for health and why mitochondrial dysfunction is the bane of wellness and healthspan) and red light therapy. This week, again, we will cover the topic of methylene blue (MB) in great depth; including the history of MB, the mechanisms of MB, the health benefits and correlative research on MB, and considerations surrounding MB for those deliberating the potential use of MB for their health and wellness goals. With that being said, make sure your brain is full of flowing electrons and buckle up for an information-packed episode! If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key Points: [00:00] - Introduction to the Red Light Report [00:31] - Embracing Seasonal Rhythms [03:12] - Redox Before You Detox [05:18] - Adapting to Winter's Light Environment [07:09] - Recap of the Mitochondrial Triad [08:20] - Ketogenic Diet and Mitochondria [10:26] - Starting the Presentation's Second Half [11:23] - Red Light Therapy Considerations [14:35] - Methylene Blue: History and Benefits [16:52] - Methylene Blue's Role in Oxygen Delivery [19:11] - Psychiatry and Methylene Blue [21:20] - The Dual Nature of Red Light Therapy in Cancer [22:24] - Methylene Blue and Cancer Research [24:07] - Voltage and Cellular Health [25:28] - Photodynamic Therapy and Red Light Synergy [27:20] - Enhancing Wellness Through Methylene Blue and Red Light [28:41] - Mitochondrial Impact Across Species [29:15] - Methylene Blue in Mitochondrial Research [30:18] - Mechanisms of Methylene Blue in Electron Transport [33:33] - Unique Antioxidant Properties of Methylene Blue [35:05] - Nitric Oxide: Friend or Foe? [38:42] - Oxygenation and Organ-Specific Benefits [39:41] - Mitochondrial Biogenesis [40:34] - Methylene Blue's Health Benefits and Research [43:02] Introduction to Neuroprotection [43:14] Methylene Blue as a Potent Antioxidant [45:14] Impact on Brain and Cognitive Function [48:34] Antimicrobial and Antiviral Properties [49:55] Cancer Therapeutic Potential [51:07] Anti-Aging Benefits [52:25] Synergy with Red Light Therapy [53:03] Methylene Blue Considerations [59:44] Interaction with SSRIs [1:01:17] Practical Usage Notes [1:02:31] Conclusion and Wrap-Up - Save 20% when you purchase via The Mitochondrial Triad Bundle!Choose any one RLT device + one BioBlue supplement + one BioC60 supplement = save 20% on the entire order! No discount code necessary, click here to order! - Dr. Mike's #1 recommendations: Water products: Water & Wellness Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram YouTube Facebook
Does Calorie Restriction Even Work? What About the Carnivore Diet AND Fruit? Today we are excited to have Paul Saladino join us for a masterclass on food and diets. Dr. Saladino dives into the evolution of keto and carnivore diets, cutting through trends to focus on lasting health impacts. Dr. Saladino, widely recognized as CarnivoreMD, shares how his own diet shifted to include fruit and honey alongside animal-based nutrition, and why metabolic flexibility—not rigid rules—leads to better outcomes. Together, he and Dave challenge assumptions about long-term ketosis, examine its potential downsides, and explore how to optimize diets for energy, gut health, and longevity. They also tackle controversial topics like the risks of seed oils, the overhyped reputation of “health foods” like quinoa, and the critical roles insulin and nutrient density play in overall wellness. With insights on balancing mTOR, managing omega fats, and incorporating organ meats, this episode offers a nuanced perspective for anyone interested in biohacking, nutrition science, or simply eating smarter. What you'll learn: • Why metabolic flexibility matters more than strict diet rules • The science behind long-term ketosis and insulin's broader role in health • How common “health foods” could be doing more harm than good • The importance of nutrient-dense animal-based foods for gut and immune health • How to achieve optimal balance between fat types, mTOR, and longevity markers Resources: 2025 Biohacking Conference – https://biohackingconference.com/2025 Shop Paul Saladino's Products – https://heartandsoil.co Follow Paul Saladino on Instagram – https://www.instagram.com/paulsaladinomd/ Paul Saladino's Book: The Carnivore Code – https://www.amazon.com/Carnivore-Code-Unlocking-Returning-Ancestral/dp/035846997X Lineage Provisions – 100% Grass-Fed Beef Tallow – https://lineageprovisions.com/products/100-grass-fed-beef-tallow Danger Coffee – https://dangercoffee.com Danger Coffee Instagram – https://www.instagram.com/dangercoffeeofficial/ Dave Asprey's Website – https://daveasprey.com Dave Asprey's Book: Smarter Not Harder – https://daveasprey.com/books Dave Asprey's Linktree – https://linktr.ee/daveasprey Upgrade Collective: Join The Human Upgrade Podcast Live – https://www.ourupgradecollective.com Own an Upgrade Labs – https://ownanupgradelabs.com Upgrade Labs – https://upgradelabs.com 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement – https://40yearsofzen.com Sponsors: - Timeline | Head to https://www.timeline.com/dave to get 10% off your first order. - LMNT | Free LMNT Sample Pack with any drink mix purchase by going to https://drinklmnt.com/dave. Timestamps: • 00:00 Intro • 00:40 Paul Saladino's Evolution in Diet • 01:21 Challenges of a Strict Carnivore Diet • 03:36 Reintroducing Carbohydrates • 05:32 Debunking Common Diet Myths • 13:49 The Problem with Calorie Restriction • 18:30 The Importance of Food Quality • 24:08 The Veganism Debate • 34:15 The Benefits of Organ Meats • 37:27 Foot Surgery and Bone Density • 39:23 Mineral Deficiency and Plant-Based Diets • 40:00 The Truth About Seed Oils • 41:10 Historical Studies on Seed Oils • 47:26 Mechanisms and Effects of Seed Oils • 52:33 Nicotine and Neuroprotection • 54:12 Oleic Acid and Longevity • 01:01:44 The Benefits of Animal Fats• 01:02:32 Odd Chain Fatty Acids and Health • 01:11:07 Cheese and Dairy Considerations • 01:13:11 The Impact of Cheese on Health • 01:14:03 Protein Intake and Longevity • 01:14:54 Understanding mTOR and Its Effects • 01:17:35 Ideal Body Fat and Metabolic Health • 01:24:38 The Role of Omega Fatty Acids • 01:32:46 ApoB, Insulin Sensitivity, and Longevity • 01:43:09 Final Thoughts and Product Recommendations See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In today's episode, host Chris Duffin dives deep into the fascinating world of cognitive enhancement with special guest Anthony Castor. We'll explore a range of nootropic peptides and supplements designed to boost brain function, resilience, and overall well-being. Chris and Anthony discuss such potent peptides as C Max and Celnac, revealing their roles in cognitive enhancement, neuroprotection, and stress resistance. We'll learn about Synapsin's ginsenoside RG3, and its anti-aging properties, and the intriguing nootropic properties of NewPEPT. Listen as Anthony shares personal anecdotes about using compounds like Dihexa for synapse formation and modafinil for enhancing wakefulness and cognitive performance. Throughout the conversation, we'll also delve into the science behind these compounds, examining their neurotransmitter modulation, neuroprotection, and practical applications for high-stress jobs, shift work, and productivity boosts. Additionally, we'll cover lifestyle practices that complement these cognitive enhancers, emphasizing the importance of sleep, hydration, and a balanced diet. This episode of the ARCHITECT of RESILIENCE podcast is available on Apple, Spotify & YouTube, and is sponsored by @marekhealth : Performance. Longevity. Optimization.
Get My Book On Amazon: https://a.co/d/avbaV48Download The Peptide Cheat Sheet: https://peptidecheatsheet.carrd.co/
If you or someone in your family deals with Parkinson's, Alzheimer's or you're simply in midlife dealing with changing hormones, this episode and the book we're discussing, Heal your gut, save your brain, will be one you don't want to miss. My Guest: Dr. Partha Nandi, M.D., F.A.C.P is the creator and host of the internationally syndicated medical lifestyle television show, Ask Dr. Nandi. He is the Chief Health Editor at WXYZ ABC Detroit, a practicing physician, renowned international speaker, appearing at TEDx, medical conferences like Digestive Disease Week and keynotes for organizations such as Medtronic, Phathom Pharmaceuticals, and Eli Lilly. Dr. Nandi partners with global health organizations, including the Ministry of Health in Jamaica and India and WHO. He give inspiring talks to international conferences and symposia, meeting global health leaders. His mission, “To Be Your Own Health Hero,” incourages individuals to take control of their health. His latest book, “Heal Your Gut, Save Your Brain”, explores the connection between gut and brain health. Questions We Answer in This Episode: What inspired you to write "Heal Your Gut, Save Your Brain"- [00:05:25] Explain the gut-brain axis and why it is so critical for overall health?- [00:09:26] How did your father's stroke influence your research?- [00:06:38] What are the most surprising connections between the gut and brain? - [00:10:15] How does the gut influence conditions like depression and anxiety? - [00:12:41] What are some practical steps to improve gut and brain health? - [00:18:43] How do lifestyle factors such as diet, exercise, and stress management play a role in maintaining a healthy gut-brain connection? - [00:22:10] Can you talk about your Five Pillars for Optimal Health? - [00:19:16] Can you share real-life gut health success stories? - [00:34:08] What are the key takeaways of your book, “Heal Your Gut, Save Your Brain”? - [00:42:01] Connect with Dr. Nandi: https://www.AskDrNandi.com On Social: Facebook: https://www.facebook.com/AskDrNandi/ Instagram: https://www.instagram.com/askdrnandi/ Tiktok: https://www.tiktok.com/@askdrnandi LinkedIn: https://www.linkedin.com/in/askdrnandi/ Twitter: https://twitter.com/askdrnandi Other Episodes You Might Like: Your Brain Better | A No Negative Side-Effects Method: https://www.flippingfifty.com/your-better-brain/ Get and Keep Your Brain Fit, Healthy, and Strong: https://www.flippingfifty.com/leaky-brain/ Lose Weight, Gain Energy and Eliminate Pain with a Gut Cleanse: Dr Vincent M. Pedre: https://www.flippingfifty.com/lose-weight-gain-energy-and-eliminate-pain-with-a-gut-cleanse-dr-vincent-m-pedre/ Events or Affiliate partnership we're promoting in this episode: Resources: https://www.healyourgutsaveyourbrain.com/
Send me a text!Introduced by German chemist Heinrich Caro as a textile dye in the 19th century, methylene blue soon attracted the interests of notable scientists like Robert Koch and Paul Ehrlich. Recognizing its unique antimicrobial properties, they helped transition it from textile labs to medical clinics. By the early 20th century, methylene blue had gained recognition as an innovative malaria treatment, a role it continues to have today. Methylene blue may also offer a wide range of other significant health benefits, beyond fighting infections. By acting as an “electron donor”, methylene blue supercharges your mitochondria, or the powerhouses of your cells. Join me as I sit down with Dr. Scott Sherr, MD, and explore how this incredible compound is currently being used to treat chronic illness, boost cognitive functioning, improve energy, reduce inflammation, and even offer anti-aging benefits.Suggested Resources:Dr. Scott Sherr | InstagramTroscriptionsThe Potentials of Methylene Blue as an Anti-Aging DrugMethylene Blue–Mediated Antimicrobial Photodynamic Therapy Against InfectionFrom Mitochondrial Function to Neuroprotection-an Emerging Role for Methylene BlueThis episode is proudly sponsored by Qualia Life. As you approach 30, there's a subtle form of aging that starts before you even notice it, and you should know about it BEFORE it picks up momentum: senescent cell accumulation. These cells start accumulating in us over time, draining our energy and accelerating aging, contributing to typical aging symptoms like reduced energy, slower recovery, and joint discomfort. Qualia Senolytic combines 9 vegan, plant-derived compounds to help your body naturally eliminate senescent cells, that help us age better at the cellular level so we can feel YEARS younger!Get support for slaying YOUR zombie cells now with Qualia Senolytic at qualialife.com/wellnstrong and code WELLNSTRONG for 15% off.Qualia Senolytic combines 9 vegan, plant-derived compounds to help your body naturally eliminate zombie (or senescent) cells, that help us age better at the cellular level so we can feel YEARS younger! Use the code WELLNSTRONG for 15% off!Join the WellnStrong mailing list for exclusive content here!Want more of The How To Be WellnStrong Podcast? Subscribe to the YouTube channel. Follow Jacqueline: Instagram Pinterest TikTok Youtube To access notes from the show & full transcripts, head over to WellnStrong's Podcast Page
In this episode, we have the privilege of speaking with Dr. Michael Lewis, renowned expert in brain health and traumatic brain injury (TBI), and author of the groundbreaking book, When Brains Collide. Dr. Lewis is the founder of the Brain Health Education and Research Institute and BrainCARE. With a military background and extensive experience in traumatic brain injuries, Dr. Lewis has dedicated his career to exploring how omega-3 fish oils can play a vital role in preventing and recovering from concussions, TBI, stroke, and neurodegenerative diseases. Key Discussion Points 1. The Role of Omega-3 Fish Oils in Brain Health Docosahexaenoic Acid (DHA) and Eicosapentaenoic Acid (EPA), the primary omega-3 fatty acids found in fish oil, are crucial for maintaining brain structure and function. Omega-3s are anti-inflammatory and neuroprotective, making them vital in protecting the brain from injury and supporting recovery. 2. High-Dose Omega-3 Fish Oil for Concussions and Traumatic Brain Injury (TBI) Dr. Lewis emphasizes how high-dose fish oil can help mitigate damage following a concussion or TBI. Dosing Protocols: In acute brain injury cases, Dr. Lewis recommends significantly higher doses of fish oil (e.g., up to 3-9 grams of combined DHA and EPA per day) to reduce inflammation, promote healing, and restore brain cell membrane integrity. Case studies demonstrate remarkable improvements in TBI patients, including quicker recovery times, reduced brain fog, and restored cognitive function. 3. Fish Oils for Neurodegeneration and Stroke Prevention Regular intake of omega-3s is shown to be effective in reducing the risk of neurodegenerative diseases like Alzheimer's and Parkinson's. Omega-3s help prevent stroke by reducing blood clot formation, improving vascular health, and lowering inflammation in brain tissues. Dr. Lewis advocates for omega-3s as part of a preventive strategy, particularly for aging individuals at higher risk of neurodegenerative conditions. 4. Using Omega-3s as Preventive Medicine Consistent omega-3 supplementation is not just for recovery—it's crucial for maintaining optimal brain health. Athletes, military personnel, and individuals at risk for head trauma should use omega-3s proactively to strengthen their brain's resilience to injury. Preventative Dosing: Dr. Lewis suggests a daily intake of at least 2-3 grams of DHA and EPA combined for ongoing brain health and injury prevention. 5. How to Choose a High-Quality Fish Oil Dr. Lewis explains the criteria for identifying a high-quality fish oil supplement: Purity: Free from contaminants like heavy metals and toxins. Potency: Look for a high concentration of DHA and EPA. Stability: Avoid fish oils that oxidize easily, as rancid oils can be harmful. Sourcing: Prefer fish oils sourced from wild-caught, sustainably harvested fish. Importance of third-party testing to ensure the product is safe and effective. 6. Personal Stories and Case Studies Dr. Lewis shares inspiring stories of patients and athletes who have successfully used omega-3 therapy to recover from brain injuries. Examples include a football player who recovered from multiple concussions and a stroke survivor who regained cognitive function with high-dose omega-3 supplementation. 7. How to Use Omega-3s After Brain Injury Immediate supplementation following a brain injury can make a significant difference in recovery outcomes. The sooner omega-3s are introduced post-injury, the better. Dr. Lewis provides insight into the timing and administration of omega-3 supplements during the acute phase of brain injury treatment. Recommended Resources: Dr. Michael Lewis's Website: Brain Health Education and Research Institute: http://www.brainhealtheducation.org/ BrainCARE: BrainCARE Center When Brains Collide Book Join us for this enlightening discussion on the powerful benefits of omega-3 fish oils for brain protection, recovery, and overall health. Dr. Michael Lewis's pioneering work is transforming how we approach brain injuries and neurodegeneration, highlighting the critical role that nutrition and supplementation play in maintaining cognitive vitality. Tune in to learn how you can harness the power of omega-3s for your brain health and optimize your recovery from injury or disease. BIO Michael Lewis, MD, MPH, MBA, FACPM, FACN, is a proven leader and expert in the treatment and management of concussions and brain injuries. He also applies his holistic approach to Men's Health and outpatient orthopedics. Upon retiring as a Colonel in the U.S. Army, he founded the nonprofit Brain Health Education and Research Institute and entered private practice focusing on helping patients with chronic concussion issues. His pioneering work in the military and since has helped thousands of people around the world and he is regularly featured in the media, radio, podcasts, webinars, scientific conferences, and television. A lifelong athlete, Dr. Lewis serves on the Pop Warner Youth Football Medical Advisory Board and Board of Directors of National Collegiate Rugby where is also the head of the Medical and Safety Committee. Dr. Lewis is the author of When Brains Collide: What Every Athlete and Parent Should Know About the Prevention and Treatment of Concussions and Head Injuries. He is a graduate of the U.S. Military Academy at West Point and Tulane University School of Medicine. He is board- certified and a Fellow of the American College of Preventive Medicine and American College of Nutrition. He completed post-graduate training at Walter Reed Army Medical Center, Johns Hopkins University, and Walter Reed Army Institute of Research. Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with: Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. Testing Options Comprehensive Thyroid testing DUTCH Hormone testing Adrenal Testing Organic Acid Testing Microbiome Testing Cell Blueprint Testing Epigenetics Testing DNA testing Basic Blood Test analysis Heavy Metals Nutristat Omega 3 to 6 status and more Lisa and her functional medicine colleagues in the practice can help you navigate the confusing world of health and medicine . She can also advise on the latest research and where to get help if mainstream medicine hasn't got the answers you are searching for whatever the challenge you are facing from cancer to gut issues, from depression and anxiety, weight loss issues, from head injuries to burn out to hormone optimisation to the latest in longevity science. Book your consultation with Lisa Join our Patron program and support the show Pushing the Limits' has been free to air for over 8 years. Providing leading edge information to anyone who needs it. But we need help on our mission. Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to https://www.buymeacoffee.com/LisaT to donate $3 Lisa's Anti-Aging and Longevity Supplements Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world. This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life. Subscribe to our popular Youtube channel with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge" Check them all out at https://shop.lisatamati.com/collections/books Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here: Use code "tamati" at checkout to get a 10% discount on any of their devices. Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38 Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa and team
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, as she discusses the latest research on the effects of exercise on brain health. Stay informed and proactive about maintaining cognitive function as you age with insights from cutting-edge research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40062]
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, as she discusses the latest research on the effects of exercise on brain health. Stay informed and proactive about maintaining cognitive function as you age with insights from cutting-edge research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40062]
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, as she discusses the latest research on the effects of exercise on brain health. Stay informed and proactive about maintaining cognitive function as you age with insights from cutting-edge research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40062]
What can you do today to improve or maintain your brain health? Join Sarah Banks, Ph.D., a leading expert in healthy aging, dementia, and Alzheimer's disease, as she discusses the latest research on the effects of exercise on brain health. Stay informed and proactive about maintaining cognitive function as you age with insights from cutting-edge research. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40062]
About the Guest(s): Dr. Kristin Hieshetter Dr. Kristin Hieshetter is a seasoned chiropractor and expert in functional health. She has a profound passion for educating people about the human body's amazing capabilities and bringing it to its fullest potential. As the host of Functional Health Radio, she shares her extensive knowledge of cutting-edge health topics and provides actionable advice to help listeners improve their well-being. Dr. Hieshetter is particularly focused on the role of mitochondria in various health conditions and has dedicated much of her work to advancing the understanding and application of functional health principles. Episode Summary: In this enlightening episode of Functional Health Radio, Dr. Kristin Hieshetter delves into the alarming decline in life expectancy in the United States and the surge in chronic diseases among children. Exploring the reasons behind this health crisis, she introduces the audience to the critical role of mitochondria—the energy powerhouses of our cells—and how their dysfunction can lead to various degenerative diseases. Dr. Hieshetter discusses the innovative therapeutic potential of methylene blue, a compound originally used as a textile dye, which has now emerged as a miracle drug for its remarkable effectiveness in treating conditions such as Alzheimer's, Parkinson's, stroke, and mitochondrial dysfunction. She breaks down the biochemistry of methylene blue, its history, and how it can enhance energy production, reduce inflammation, and support neurogenesis. The episode is filled with actionable insights, scientific explanations, and inspirational stories, making it a must-listen for anyone interested in optimizing their health and unlocking the human body's true potential. Key Takeaways: Mitochondria and Health: The importance of mitochondria in energy production and how their dysfunction contributes to chronic diseases. Methylene Blue as a Miracle Drug: The transition of methylene blue from a textile dye to a potent therapeutic agent with applications in treating malaria, brain diseases, and supporting mitochondrial health. Impact on Neurodegeneration: Methylene blue's ability to protect against neurodegenerative diseases, enhance mitochondrial function, and promote new neuronal growth. Scientific Backing: Extensive research supporting methylene blue's effectiveness in reducing free radicals, improving brain function, and aiding recovery from traumatic injuries. Practical Usage Tips: Guidelines for using methylene blue safely and effectively, including dosages and considerations for individuals on specific medications. Notable Quotes: "We are walking around in the most amazing, intelligent, responsive, adapting, and aware system in the world, the human body." "Methylene blue not only protects your mitochondria but enhances the growth of new neurons, the growth of new synapses, and thereby enhances neurogenesis." "In Alzheimer's disease, methylene blue upregulates complex four to help you speed up metabolism so the body can have more energy." "Imagine that—to take methylene blue if you know you've got a leaky gut to protect your heart valves from things like strep and E. coli hanging out in your heart." "Methylene blue reduces lipid peroxidation. What's the most important lipid in your entire body? Your brain." Resources: "Neuroprotection: An Emerging Role for Methylene Blue" - Journal Molecular Neurobiology, June 2018, Volume 55, Pages 5137-51. "Methylene Blue Delays Cellular Senescence and Enhances Key Mitochondrial Biochemical Pathway" - Journal FASEB, March 2008. "The Protective Role of Methylene Blue in Alzheimer's Disease via the Mitochondrial Function and Cytochrome c Oxidase" - Journal of Alzheimer's Disease, 2010. Previous episodes of Functional Health Radio discussing methylene blue and the benefits of extra virgin olive oil. Functional Health Mastery Dr. Kristin's passionate and knowledgeable approach makes this episode a compelling listen for anyone interested in functional health and the role of mitochondria in overall wellness. Don't miss out on the invaluable insights—tune in to unlock the secrets to a healthier, more vibrant life. Stay tuned for more impactful episodes on Functional Health Radio!
In today's episode, we dive into the crucial roles that gut-derived microbial metabolites, particularly short-chain fatty acids and tryptophan metabolites, play in supporting the health of neurons and glial cells, ultimately promoting cognitive function. We explore how enhancing the body's natural production of these metabolites through a healthy gut microbiome and how strategic supplementation can both benefit brain health. The discussion includes detailed insights into the cellular mechanisms in the brain and practical strategies for fostering a healthy gut microbiome capable of producing high quantities of these beneficial compounds. Topics: 1. Introduction to Brain Cellular Makeup - Overview of Neurons and Glial Cells - Neurons: Structure and Function - Glial Cells: Types and Roles 2. Neuronal Communication and Synaptic Function - Neuronal Structure: Soma, Dendrites, Axon - Synaptic Communication: Presynaptic Terminal, Synaptic Cleft, Postsynaptic Membrane 3. Energy Demands - ATP Utilization and Energy Demands - Mitochondrial Function and Neuronal Vulnerability 4. Astrocytes and Microglial Cells - Astrocytes: Functions and Role in CNS Homeostasis - Microglial Cells: Immune Functions and Role in Neuroinflammation 5. Roles of Gut-Derived Microbial Metabolites in Supporting Brain Health - Overview of Gut-Derived Metabolites - Short-Chain Fatty Acids (SCFAs): Acetate, Propionate, Butyrate - Tryptophan Metabolites: Indole, Indole-3-Propionate (IPA) 6. Impact of Gut-Derived Metabolites on Neurons - Promotion of Neurogenesis by SCFAs - Neuroprotective Effects of Tryptophan Metabolites 7. Impact of Gut-Derived Metabolites on Glial Cells - Impact on Astrocytes - Impact on Microglial Cells 8. Strategies to Enhance Metabolite Production - Diversity - Probiotic Supplementation - Fiber - Amino Acids 9. Direct Supplementation Options - Sodium Butyrate: Role in Neuroprotection and Cognitive Function Thank you to our episode sponsors: 1. Check out Daily Nouri and use code CHLOE20 for 20% off your order. 2. Check out AX3 Astaxanthin and use discount code CHLOE20 for 20% off your first order. 3. Check out Liver Medic and use code Chloe20 to save 20% on "Leaky Gut Repair" Brendan's YouTube Channel https://x.com/livermedic Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
In this episode, we delve into the critical role of neuroprotection in pre-hospital care, particularly in pediatric head injuries. Through a real-life case study of a 13-year-old boy who suffered a traumatic brain injury after being hit by a car, we explore the steps taken by paramedics and critical care teams to stabilize him and prevent further neurological damage. From airway management to advanced interventions, this episode highlights the challenges of pre-hospital neuroprotection and the incredible teamwork that led to the patient's remarkable recovery. There is more detail on the full blogpost here. This podcast was recorded live at the Hope Church in Winchester as part of the PREMIER conference. We are grateful to the organizing team for hosting us and allowing us to use the audio. The PIER and PREMIER websites are full of amazing resources for anyone working in Paediatric Emergency Medicine, and we highly recommend them. The Speaker Ed is a Speciality Trainee in Emergency Medicine in Wessex and a trainee Critical Care Practitioner with Dorset and Somerset Air Ambulance. Ed is also the co-founder and Managing Director of Enhanced Care Services, a Southampton-based company delivering enhanced and critical care to the event medical sector, providing frontline ambulance services across Hampshire and clinical education at all levels, employing over 200 clinicians. Ed holds the Diploma in Immediate Medical Care (RCSEd) and, having promised to not take on any more work, is currently undertaking a Masters in Resuscitation, Pre-hospital and Emergency Medicine at QMUL. Enhanced Care Services Enhanced Care Services' mission is to provide and influence excellent patient care, irrespective of injury, illness or location, through the delivery of high-quality clinical operations and education. Founded in 2015, ECS now provide frontline ambulance operations across the South, delivers extensive medical cover to some of the most prestigious events across the UK and provides education from its bespoke education centre in Southampton and beyond.
In this comprehensive video, we delve into various advanced therapies and supplements that can significantly enhance brain health and support recovery from brain injuries. Join us as we explore the science behind exogenous ketones, Dihexa, Cerebrolysin, Selank, Semax, plasmalogens, hyperbaric oxygen therapy (HBOT), and photobiomodulation. Learn how these innovative treatments work and their potential benefits for cognitive function and brain health. Topics Covered: Exogenous Ketones: Alternative energy source for the brain, anti-inflammatory effects, neuroprotection, and promotion of brain plasticity. Dihexa: Neurogenic and neurotrophic properties, enhancement of cognitive function, and promotion of synaptogenesis and neurogenesis. Cerebrolysin: Neurotrophic factors, neuroprotection, neuroplasticity, and cognitive function improvement. Selank and Semax: Anxiolytic and cognitive-enhancing effects, neuroprotection, and influence on neurotransmitter systems. Plasmalogens: Phospholipids, membrane integrity, oxidative stress reduction, and support for neurogenesis. Hyperbaric Oxygen Therapy (HBOT): Enhanced oxygen delivery, reduced inflammation, neuroprotection, and promotion of neurogenesis and angiogenesis. Photobiomodulation: Red and near-infrared light therapy, mitochondrial function enhancement, and neuroprotection. Research References: Cerebrolysin: - Study on Cerebrolysin and Neuroprotection in Stroke Journal of Neurology - Research on Cerebrolysin's impact on cognitive function and neuroplasticity. Dihexa: - Dihexa's Effects on Cognitive Enhancement and Neurogenesis Neuroscience Letters - Study on Dihexa and its binding to HGF receptors, promoting synaptogenesis. Selank and Semax: - Selank: Anxiolytic and Cognitive-Enhancing Properties - Semax: Neuroprotective and Cognitive-Enhancing Effects Journal of Molecular Neuroscience - Research on Selank and Semax's mechanisms and benefits. Hyperbaric Oxygen Therapy (HBOT): - HBOT for Stroke Recovery Journal of Neurotrauma - Studies on the effectiveness of HBOT in brain injury recovery and neuroprotection. Key Points: Exogenous ketones provide an alternative energy source and possess anti-inflammatory and neuroprotective properties. Dihexa enhances cognitive function by promoting neurogenesis and synaptogenesis. Cerebrolysin supports neuronal survival, neuroplasticity, and cognitive function. Selank and Semax offer anxiolytic and cognitive-enhancing benefits, influencing neurotransmitter systems and providing neuroprotection. Plasmalogens support membrane integrity, reduce oxidative stress, and promote neurogenesis. HBOT enhances oxygen delivery, reduces inflammation, promotes neuroprotection, and supports neurogenesis and angiogenesis. Photobiomodulation uses red and near-infrared light to enhance mitochondrial function and provide neuroprotection. Personalised Health Optimisation Consulting with Lisa Tamati Lisa offers solution focused coaching sessions to help you find the right answers to your challenges. Topics Lisa can help with: Lisa is a Genetics Practitioner, Health Optimisation Coach, High Performance and Mindset Coach. She is a qualified Ph360 Epigenetics coach and a clinician with The DNA Company and has done years of research into brain rehabilitation, neurodegenerative diseases and biohacking. She has extensive knowledge on such therapies as hyperbaric oxygen, intravenous vitamin C, sports performance, functional genomics, Thyroid, Hormones, Cancer and much more. She can assist with all functional medicine testing. 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Please join our patron community and get exclusive member benefits (more to roll out later this year) and support this educational platform for the price of a coffee or two You can join by going to Lisa's Patron Community Or if you just want to support Lisa with a "coffee" go to https://www.buymeacoffee.com/LisaT to donate $3 Lisa's Anti-Aging and Longevity Supplements Lisa has spent years curating a very specialized range of exclusive longevity, health optimizing supplements from leading scientists, researchers and companies all around the world. This is an unprecedented collection. The stuff Lisa wanted for her family but couldn't get in NZ that's what it's in her range. Lisa is constantly researching and interviewing the top scientists and researchers in the world to get you the best cutting edge supplements to optimize your life. Subscribe to our popular Youtube channel with over 600 videos, millions of views, a number of full length documentaries, and much more. You don't want to miss out on all the great content on our Lisa's youtube channel. Youtube Order Lisa's Books Lisa has published 5 books: Running Hot, Running to Extremes, Relentless, What your oncologist isn't telling you and her latest "Thriving on the Edge" Check them all out at https://shop.lisatamati.com/collections/books Perfect Amino Supplement by Dr David Minkoff Introducing PerfectAmino PerfectAmino is an amino acid supplement that is 99% utilized by the body to make protein. PerfectAmino is 3-6x the protein of other sources with almost no calories. 100% vegan and non-GMO. The coated PerfectAmino tablets are a slightly different shape and have a natural, non-GMO, certified organic vegan coating on them so they will glide down your throat easily. Fully absorbed within 20-30 minutes! No other form of protein comes close to PerfectAminos Listen to the episode with Dr Minkoff here: Use code "tamati" at checkout to get a 10% discount on any of their devices. Red Light Therapy: Lisa is a huge fan of Red Light Therapy and runs a Hyperbaric and Red Light Therapy clinic. If you are wanting to get the best products try Flexbeam: A wearable Red Light Device https://recharge.health/product/flexbeam-aff/?ref=A9svb6YLz79r38 Or Try Vielights' advanced Photobiomodulation Devices Vielight brain photobiomodulation devices combine electrical engineering and neuroscience. To find out more about photobiomodulation, current studies underway and already completed and for the devices mentioned in this video go to www.vielight.com and use code “tamati” to get 10% off Enjoyed This Podcast? If you did, subscribe and share it with your friends! If you enjoyed tuning in, then leave us a review and share this with your family and friends. Have any questions? You can contact my team through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. 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In this episode, we explore the intricacies of neuronal communication, delving into how neurons transmit signals through synaptic connections using neurotransmitters like glutamate and GABA. We also examine the effects of neurotoxins, such as heavy metals and environmental pollutants, on these critical synaptic pathways, leading to cognitive and neurological impairments. Lastly, we discuss neuroprotective strategies to mitigate neurotoxin exposure and promote optimal brain health. Topics: 1. Overview of Brain Cell Anatomy - Types of brain cells: neurons and glial cells. - Structure of neurons: - Soma (cell body): contains nucleus and organelles. - Dendrites: receive signals from other neurons. - Axon: transmits electrical impulses away from the soma. - Synaptic terminals: form synapses with target cells. 2. Neuronal Communication - Synapse structure: - Presynaptic terminal. - Synaptic cleft. - Postsynaptic membrane. - Neurotransmitters: - Role in neuronal communication. - Excitatory neurotransmitters (e.g., glutamate). - Inhibitory neurotransmitters (e.g., GABA). 3. Summary of Neuronal Communication - Recap of excitatory and inhibitory neurotransmitters. - Importance of maintaining proper neuronal communication. 4. Neurotoxins and Their Effects - Types of neurotoxins: - Heavy metals (e.g., lead, mercury, arsenic, cadmium, aluminum). - Chemical neurotoxins (e.g., organophosphates, solvents). - Biological toxins (e.g., mycotoxins). - Environmental pollutants (e.g., PCBs, dioxins). - Mechanisms of neurotoxin damage: - Disruption of neurotransmitter release. - Impairment of receptor function. - Interference with ion channel operation. 5. Example: Mercury's Impact on Cognitive Function - Pathway of mercury exposure and accumulation in the brain. - Disruption of calcium homeostasis and synaptic transmission. - Resulting cognitive impairments. 6. Strategies to Reduce Neurotoxin Exposure - Nutrition: - Opting for organic produce. - Washing produce properly. - Avoiding MSG and aspartame. - Limiting aluminum exposure (baking powder). - Evaluating cookware. - Avoiding farmed salmon. - Water and air quality: - Using water filtration to remove fluoride. - Choosing fluoride-free toothpaste. - Improving air quality and mold remediation. - Using air-purifying plants (e.g., aloe vera, English ivy). - Reducing exposure to places with highly-concentrated neurotoxic chemicals (e.g., nail salons). Thank you to our episode sponsor: Tremetes, LLC Use code CHLOE15 to get 15% off Tremetes' Turkey Tail Thanks for tuning in! Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellness Follow Chloe on TikTok @chloe_c_porter Visit synthesisofwellness.com to purchase products, subscribe to our mailing list, and more! --- Support this podcast: https://podcasters.spotify.com/pod/show/chloe-porter6/support
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