Podcasts about Assay

Filling in for Adam Holz, Plugged In's Paul Asay joins Brian for a rich conversation on Christopher Nolan's The Odyssey, discussing how the film softens Homer's original, more selfish Odysseus into a more sympathetic, regret-capable character, and pointing out surprising echoes of Christian themes — humility before a higher power, a quasi-baptism scene, and the Golden Rule woven throughout. Paul also recommends The Magic Faraway Tree, a new family film starring Claire Foy and Andrew Garfield about screen-addicted kids whose parents pull them into a magical, tech-free adventure, with some fantasy elements Christian families should weigh. He closes with an all-time classic recommendation for family movie night: The Princess Bride.See omnystudio.com/listener for privacy information.

Vizsla Copper provides an exploration update from its 2026 diamond drill program at the Palmer VMS project in Alaska. CEO Craig Parry was interviewed by Mining Stock Daily. The 2026 program is advancing on schedule with two diamond drill rigs currently operating. Initial drilling has intersected thick intervals of semi-massive and massive sulphide mineralization within the South Wall Zone, while continuing to refine the company's understanding of the geological and structural controls on mineralization. Assay results from the initial drill holes are pending. At its Thira discovery in central B.C., the company drilled 304.8 metres of 0.48% CuEq. Parry said the second drill program at the Poplar Project has significantly advanced the company's understanding of the system at the Thira target, where the team is working to define a large-scale copper porphyry system.

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

Men with non-obstructive azoospermia may undergo microscopic testicular sperm extraction, or mTESE, without knowing whether sperm will be found. Kun Tan, Ph.D., of UC San Diego explains how molecular semen analysis could provide a noninvasive way to predict the procedure's outcome. The assay uses stage-specific germ cell markers identified through single-cell RNA sequencing, then measures those markers in semen with qPCR. Because semen contains germ cells from different stages of sperm development, their molecular signals may reflect what is happening inside the testes. Tan shows how the assay predicts whether sperm retrieval was successful and can identify where sperm development may be blocked. The research could help couples planning IVF or ICSI avoid unnecessary surgery, reduce financial and emotional burdens, and receive more detailed information about male infertility before treatment. Series: "Motherhood Channel" [Health and Medicine] [Show ID: 41630]

In this special episode of The Pet Food Science Podcast Show, our co-host Dr. Jan Suchodolski from Texas A&M University explains why validated analytical methods are essential for reliable pet nutrition and gastrointestinal research. He discusses assay development, biomarker validation, omics technologies, microbiome analysis, and the role of artificial intelligence in improving research quality and diagnostics. Listen now on all major platforms!"Without proper measurements, scientific discoveries about nutrition and health cannot produce reliable conclusions because inaccurate methods create uncertainty and reduce confidence in biological interpretation."Meet the guest: Dr. Jan Suchodolski is Professor, Purina PetCare Endowed Chair for Microbiome Research, Associate Director and Head of Microbiome Sciences at the Gastrointestinal Laboratory at Texas A&M University. His research focuses on gastrointestinal biomarkers, intestinal microbiota, and diagnostic development. He has published more than 400 scientific articles, received the 2024 AVMA Career Achievement in Canine Research Award. He also serves as co-host of The Pet Food Science Podcast Show. Listen to Dr. Jan Suchodolski on The Pet Food Science Podcast Show, available on all major platforms.Liked this one? Don't stop now — Here's what we think you'll love!Don't miss the chance to be part of the Pet Food Inner Circle!Join now and connect with leading experts in pet nutrition: https://petfoodinnercircle.com/What will you learn:(00:00) Highlight(01:16) Introduction(05:27) Assay validation basics(11:54) Discovery versus validation(18:33) Omics technologies(19:40) Bile acid biomarkers(26:04) Artificial intelligence(42:31) Final QuestionsThe Pet Food Science Podcast Show is trusted and supported by innovative companies like:* Trouw Nutrition* Kemin- Biorigin- Rangen Group- DietForge- WiseVAs- The Owner's Box- Elevate- ZentrixOS- Zentrix Insights

Interview with Steven Sirbovan, CEO, ICG Silver & GoldOur previous interview: https://www.cruxinvestor.com/posts/icg-silver-gold-cseicg-newly-listed-district-scale-play-fully-funded-for-drilling-9778Recording date: 27th July 2026ICG Silver & Gold Ltd. is a Nevada-focused precious metals explorer advancing the Tuscarora District, a roughly 10,000-acre, 100%-owned land package sitting at the intersection of the Carlin and Independence Trends in Elko County. Since listing on the CSE on 31 March 2026, the company's central task has been converting a large but fragmented historical dataset into a coherent, drill-ready district-scale thesis - and the latest update from CEO Steven Sirbovan suggests meaningful progress on that front.The headline development is data, not drilling: ICG's historical drilling database has grown from 25,000 to 40,000 metres, pulled from lab archives and physical records dating back to the 1960s. Critically, a third-party mineral resource geologist has assessed that database - combined with the company's current 3,000-metre Phase 1 RC programme - as sufficient to support a maiden inferred resource without any additional core drilling. That's a meaningful capital-efficiency win for a company with a tight, roughly 43-million-share basic capitalisation (54.5 million fully diluted).The Phase 1 programme itself, which commenced 2 July 2026 with Major Drilling International, budgeted at approximately $1.5 million, is sequencing six priority targets: Silica, Battle Mountain, and King's Vein in the Central Zone (roughly 80% of metres), followed by Grand Prize and East Pediment in the more silver-prospective East Zone, before returning to Modoc. Notably, South Navajo - the target with the deepest historical drilling and the district's best-known intercept (4.57m at 127.08 g/t gold, including 1.52m at 368.31 g/t gold, drilled by Novo Resources in 2016) - is being held back from Phase 1 entirely, with management confident in roughly 80% of the historical data there without further verification.Sirbovan has framed the programme's real objective as testing continuity rather than chasing standalone high-grade hits: understanding whether a lower-grade halo exists between known veins, and whether targets like Modoc, Silica, and Battle Mountain - previously treated as one system - are structurally connected at depth. QA/QC on both historical and current drilling is being led by VP Exploration Korbon McCall, who has been re-verifying historical assay certificates directly against lab records.Assay results are expected between August and October 2026, with a first mineral resource estimate targeted for Q1 2027 - management has cited an internal ambition of at least 500,000 gold-equivalent ounces as an initial baseline. Management, insiders, and significant shareholders hold over 25% of the tight capital structure. At an approximate C$18 million market capitalisation, ICG trades at a discount to profiled Nevada peers (C$24-160 million), several of which remain pre-resource themselves - leaving the upcoming assay and resource news flow as the key catalysts that could close that valuation gap, assuming results confirm the continuity thesis management has laid out.Learn more: https://www.cruxinvestor.com/companies/icg-silver-goldSign up for Crux Investor: https://cruxinvestor.com

This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.babyblueviper.com/subscribe

Lightning Minerals managing director Troy Brice talked with Proactive about the completion of phase-two exploration at the company's wholly owned Warby Tungsten Project in North Queensland. The recently completed field program collected around 90 samples from priority targets as Lightning Minerals works toward identifying potential sites for an initial drilling campaign. Brice said the program had been completed ahead of schedule and under budget, with the latest geological mapping and sampling continuing to strengthen the company's understanding of the project. Assay results are expected around mid-August. Lightning Minerals will use those results to refine its geological model and determine where clusters of higher-grade tungsten mineralisation may be present. The company is also considering geophysical work to improve the accuracy of future drill targeting and ensure exploration capital is deployed carefully. Brice also discussed Warby's location near the operating Mount Carbine tungsten mine and the strategic importance of establishing secure Australian supplies of tungsten. Depending on the results of the current program, initial drilling could take place late in the year or early the following year. Visit Proactive's YouTube channel for more interviews and market updates. Please give the video a like, subscribe to the channel and enable notifications for future content. #LightningMinerals #WarbyTungsten #Tungsten #CriticalMinerals #MineralExploration #NorthQueensland #MiningNews #ASX #Drilling #AssayResults #AustralianMining #ProactiveInvestors

Discover why PhotonAssay™ is reshaping the future of geochemical analysis, where traditional fire assay still fits, and how faster, higher-quality data helps exploration teams reduce risk, improve QA/QC, and accelerate decision-making from exploration through grade control. The discussion also covers coarse gold challenges, large-sample analysis, automation, data confidence, and why technology adoption is becoming a competitive advantage for modern mining operations.

Great Western Mining Corp PLC: More tungsten assay results from Defender-Pine Crow Great Western Mining has released the results of a machine-cut channel sampling programme undertaken at its Defender-Pine Crow tungsten project in Nevada. The company cut four channels, and each showed tungsten mineralisation comparable to other projects in the area, notably that of Guardian Metals at Pilot Mountain. More channel samples will now likely be taken as the company moves towards a drilling campaign set to get underway in the next few weeks. Meanwhile, behind the scenes, metallurgical work is also ongoing. Great Western chief executive Ed Loye joins Vox to tell us more. ▶️ Watch the full interview: https://www.youtube.com/watch?v=ReXLQQUTm5w

Andean silver has three avenues to share price growth, resource increases, upgrading inferred resources to measured and indicated, and undertaking economic studies to show how profitable this project can be. Guest Bio Matthew Allen joins The Hole Truth fresh from his appointment as Managing Director of Andean Silver Limited (ASX: ASL, OTCQX: ADSLF), having stepped up from the role of Chief Executive Officer, which he took on in February 2026 after serving as the company's Chief Financial Officer from December 2024. Allen brings more than 20 years of multi-sector business experience as an entrepreneurial leader in financial analysis, mergers and acquisitions, forecasting and strategic planning, with prior roles at Global Lithium Resources, Hastings Technology Metals and Otto Energy. He has completed the Australian Institute of Company Directors' Company Directors Course. Allen now leads Andean Silver's push to convert and grow the resource base at its 100%-owned Cerro Bayo Silver-Gold Project in Chile's Aysen region, and to advance the studies needed to underpin a future restart of the historic operation. Produced by Resource Media The Hole Truth: Mining Investment Podcast is a product of Read Corporate. Please note that Read Corporate does not provide investment advice and investors should seek personalised advice before making any investment decisions. Links The Hole Truth LinkedIn: https://www.linkedin.com/showcase/the-hole-truth-podcast The Hole Truth YouTube: https://youtube.com/playlist?list=PLI4sZkSfEpPi_u7OrD7lQ-tZHbdy6EhCC&si=iOcGscff7kMSw8c7 The Hole Truth Website: https://resourcesrisingstars.com.au/the-hole-truth-podcast/ The Hole Truth Instagram: https://www.instagram.com/theholetruthpodcast/ Company Website: https://www.andeansilver.com/   Key Insights Three Clear Avenues to Value Growth Newly appointed Managing Director Matt Allen sets out Andean Silver's three-pronged value strategy at Cerro Bayo: continuing to grow the overall resource through drilling, converting Inferred ounces into the higher-value Measured and Indicated categories, and running economic studies to quantify the project's production and cash flow potential. Allen argues each driver reinforces the others, with the recent resource upgrade providing the scale and confidence needed to justify moving into feasibility work. A 230% Jump in Indicated Resources Underpins the Next Phase Andean's latest Mineral Resource Estimate delivered a 230% increase in Indicated resources, reflecting close to 30,000 metres of infill drilling completed over the past 12 months. Allen notes the update was also the first to constrain the resource within mineable shapes rather than a simple grade cut-off, making the reported ounces more directly relevant to future mine planning. Around 4.7 million of the project's 20 million tonnes are now classified as Indicated, with the company targeting 70% Measured and Indicated at the next update. Restart Economics Take Shape After Decades of Production History Cerro Bayo has more than 30 years of production history and was placed into care and maintenance in 2022, when silver was trading below US$10 an ounce — a stark contrast to the roughly US$60 an ounce environment Andean is now planning a restart into. Continued drilling within 1.5 kilometres of the existing process plant, including deepening known mineralisation at the Cascada deposit by around 200 metres, has given the company confidence in a mine life beyond ten years. Feasibility work now underway will also weigh whether to expand the plant from 500,000 tonnes per annum toward 750,000–1 million tonnes, targeted for delivery in the second half of calendar 2027. First Drilling in Over 20 Years Targets the High-Grade Cerro Bayo District Two additional rigs are being mobilised to the Cerro Bayo district, a historic underground mining area roughly ten kilometres from the Laguna Verde process plant that once produced at close to 700 grams per tonne silver-equivalent head grade. The area has not been drilled in more than two decades, despite ongoing surface mapping by Andean's exploration team identifying extensions to known vein systems. Assay results are expected before the end of the year, with the company also planning ahead to next-generation greenfield targets along the Droughtmaster–Sinter Hill corridor. Structural Tailwinds Support the Silver Price Outlook Allen points to a market undergoing a genuine shift, with silver's industrial applications in solar photovoltaics, electronics and medical uses increasingly driving demand alongside its traditional precious metals role. On the supply side, silver remains relatively inelastic, with the majority of global production coming as a by-product of lead, zinc and copper mining rather than from dedicated silver projects. Allen notes the market has now recorded six consecutive years of supply deficits, underpinning a price that has moved from single digits historically to around US$60 an ounce today, comfortably above most industry all-in sustaining costs.

Interview with Layton Croft, President & CEO, Carolina RushOur previous interview: https://www.cruxinvestor.com/posts/carolina-rush-tsxvrush-testing-deep-porphyry-potential-in-americas-first-gold-district-9470Recording date: 1st July 2026Carolina Rush has completed the first deep drilling program at its Brewer Gold-Copper project in South Carolina, confirming the presence of a copper-gold porphyry system beneath its historic near-surface gold mine. The program, consisting of three deep holes totaling 3,500 metres, marks a significant shift in the company's exploration focus from shallow gold mineralisation to a larger, deeper target.Results from hole 37 provided early indications of a porphyry system, including elevated copper levels, the presence of chalcopyrite, and characteristic quartz veining. More importantly, hole 38 delivered a breakthrough by intersecting copper-gold mineralisation beneath the lithocap for the first time. The hole returned multiple mineralised intervals, including 60 metres grading 681 ppm copper and 0.24 g/t gold within potassic alteration, a zone typically associated with the core of porphyry deposits.A revised geological model, developed with porphyry expert Dr. Richard Sillitoe, suggests the system is tilted 20–30 degrees to the northwest rather than vertical. This interpretation implies that the mineralised core may lie at a shallower and more economically accessible depth than previously assumed.The project is being advanced through an earn-in agreement with OceanaGold, which must invest US$8 million by the end of 2027 to earn a 50% stake. Carolina Rush remains the operator, while OceanaGold brings funding and regional infrastructure, including its nearby Haile gold mine.With a defined near-surface resource of approximately 500,000 ounces of gold and growing evidence of deeper porphyry potential, Brewer represents a dual-opportunity asset. Assay results from the third hole are pending, and further drilling is planned to test the system along its interpreted northwest extension.Learn more: https://www.cruxinvestor.com/companies/carolina-rushSign up for Crux Investor: https://cruxinvestor.com

Rebekah Goldblatt, Florencia Monge, Cory Hansen, Melissa M Budelier. Tacrolimus Assay Comparison: Analytical and Operational Considerations for Immunoassay vs Mass Spectrometry Testing in a High Volume Clinical Laboratory. The Journal of Applied Laboratory Medicine, Volume 11, Issue 3, May 2026, Pages 531–541. https://doi.org/10.1093/jalm/jfaf199

Issued On Behalf of Nextech3D.ai NEXCF:OTCQX | NTAR:CSE | EP2:FSE Nextech3D.ai reported audited Q4 and full-year results for the period ended March 31, 2026, posting Q4 revenue of $939,000, up 207% year-over-year from $306,000. Gross margin reached 91.3% and gross profit climbed 263% to $858,000, while the operating loss narrowed to $(290,000) from $(7.3 million). Full-year revenue totaled $2.13 million at a 91.2% gross margin, reflecting the transition to an AI software-based model. Issued On Behalf of Falcon Gold Corp. FG:TSXV | 3FA:FSE | FGLDF:OTC Pink Falcon Gold acquired the West Hammond Contact Property, expanding its position in northwestern Ontario's Atikokan-Hammond Reef Gold District. The property covers part of the Finlayson Greenstone Belt and interpreted extensions of the Marmion Shear Zone, adjacent to Agnico Eagle's Hammond Reef deposit, which hosts roughly 3.3 million ounces of probable gold reserves and 2.3 million ounces of measured and indicated resources. It complements Falcon's flagship Central Canada Gold Project. Issued On Behalf of Maverick Gold and Silver Corp. MAV:CSE | VRCFF:OTC Pink | VR61:FSE Maverick Gold and Silver received a Mines Act Permit and Multi-Year Area-Based exploration approval from British Columbia for its Silver Vista Silver-Copper Property, about 55 kilometres northeast of Smithers. New mineral claim #1133268, covering 295.4 hectares, was also formally granted. Silver Vista now comprises 12 mineral claims spanning 5,134.5 hectares, with six additional claims still pending.Issued On Behalf of Metals Creek Resources Corp. MEK:TSXV | M1C1:FSE Metals Creek returned 40.61 g/t gold over 2.6 metres, including 152 g/t gold over 0.6 metres, from its Ogden Gold Project in Timmins, Ontario. Visible gold was intersected in all three holes of the recently completed program, alongside a strong pervasive alteration system. Assay results for the two remaining holes are pending, with core analyzed by Activation Laboratories in Thunder Bay. Canuc Resources Corporation CDA:TSXV | CNUCF:OTCQB Canuc Resources drilled 9.2 metres of 8.99 g/t gold plus a polymetallic intercept at its East Sudbury Project, roughly 20 kilometres northeast of the Sudbury Mining District. The 20,078-hectare project hosts four subparallel fault structures, and drilling at the Glade Zone included hole AG-26-144 intersecting 11.4 g/t gold over 0.8 metres. Results will guide upcoming gravity and magnetic surveys. Follow AGORACOM for more breaking small-cap news and insights.

Purepoint Uranium Group CEO Chris Frostad joined Steve Darling from Proactive to announce the start of the company's fully funded summer 2026 drill program at the Dorado Project, a 50/50 joint venture with IsoEnergy located in Saskatchewan's Athabasca Basin. The program is designed to build on the success of the Nova Discovery, where winter drilling expanded uranium mineralization along a one-kilometre structural corridor and significantly improved the company's geological understanding of the system. Frostad said the summer campaign will consist of seven drill holes totaling approximately 3,150 metres and will run through July and August. The primary objective is to further expand the Nova Discovery while also testing several high-priority regional targets across the broader Dorado property. The program follows a highly successful nine-hole winter drill campaign, which intersected anomalous radioactivity exceeding 500 counts per second (cps) in every hole drilled. Winter drilling also confirmed a peak downhole gamma reading of 73,100 cps, highlighting the strength of the uranium mineralization encountered. Assay results from the winter program remain pending. In addition to drilling, the company recently completed an airborne MobileMT geophysical survey over the Dorado Project. Results from the survey will be integrated into ongoing geological interpretation and future drill targeting efforts, helping refine exploration priorities across the property. Management believes the combination of strong drill results, advanced geophysical data, and a growing understanding of the mineralized corridor positions Dorado as one of the most promising emerging uranium discoveries in the Athabasca Basin. #proactiveinvestors #purepointuraniumgroup #tsxv #ptu #otcqb #ptuuf #UraniumExploration #NuclearEnergy #IsoEnergy #DoradoProject #UraniumExploration #AthabascaBasin #NovaDiscovery #CriticalMinerals #MiningNews #ExplorationDrilling #UraniumStocks

The Advantage of Rapid Prototyping in Wearable MedTech DevelopmentModern cancer treatments are getting better at targeting specific forms of cancer. However, this improved effectiveness often introduces lethal side effects. Skribe Medical is developing wearable technologies to help oncologists monitor and manage these side effects and ultimately improve cancer survivability.In Episode 45 of the MedTech Speed to Data podcast, Key Tech's Andy Rogers has a conversation with Ryan Neely, Skribe Medical's CEO and co-founder, about the startup's approach to rapid prototyping, clinical trials, and wearable technology.Need to knowCancer treatment can be lethal — The most effective drugs often come with black box warnings of harmful and lethal side effects.600,000 US patients are at risk of cardiotoxicity — Toxic drugs damage the heart, leading to complications like arrhythmia and heart failure.Managing cardiotoxicity can delay cancer treatments — Oncologists must now schedule patients for third-party ECG testing, which takes time and delays treatment.The nitty-grittySkribe Medical is developing a wearable ultrasound sensor that detects cardiotoxicity signals for use in oncology clinics. “We have a patch that can be worn to detect cardiotoxicity and really streamline monitoring of heart health,” Neely says. “Rather than an oncologist sending a patient to get a cardiac ultrasound, which could take weeks, the patch can just be placed above the heart for about five minutes. We record a bunch of different signals, pass them through an AI model, and then we can give them either a thumbs up or a thumbs down.”Neely goes on to explain how the in-clinic wearable approach delivers benefits beyond better patient outcomes. “The first device that we're building is intended to be used in the clinic by a nurse or a medical assistant. By the time the doctor is there, you've got your answer.”Designing a wearable device rather than an implant created several advantages for Skribe Medical during its early development. “In a regulated industry like medical devices,” Neely explains, “it's like a little bit of a chicken and egg where people say, ‘we'd like to see some clinical validation' and you're thinking, ‘Well, I don't have a million dollars to fund that.' In a non-invasive device, any opportunity that you can have to test, even if it's this big, bulky thing, you can get some data.”Skribe Medical's technology can extend to other aspects of oncology, including peripartum cardiomyopathy, a rare form of heart failure arising towards the end of a pregnancy. Long-term, Neely envisions building the longitudinal training data needed for predictive monitoring. “What we'd like to do is be able to say, ‘two weeks from now there might be an issue' so you can do something today that prevents any drop [in injection fraction] at all.”Data that made the difference:Skribe Medical's three founders built first prototype at home. They used their home electronics and 3D printing labs to rapidly prototype the first functional sensors.Rapid wearable development delivered data quickly, first by testing themselves and then through clinical testing.Skribe Medical conducted the first clinical tests at an ECG lab where, with consent, the wearable collected patient data for comparison with the patient's ECG results.Having clinical data so early in the process encouraged investors. Last year's pre-seed round raised $1.6 million from angels and VCs to support the next phase of device development and trials.Listen to Andy's conversation with Neely to hear more about Skribe Medical's journey, development process, and the advantages of wearable medical technology.

Erik Wetterling, Founder and Editor of The Hedgeless Horseman website, joins us to review the value proposition that has his attention from recent corporate news and strategies from 3 silver, copper, and gold explorers that have recently press-released significant company milestones.   The companies we discussed in the interview are:   * Silver Bow Mining Corp. (NYSE American: SBMT) – On May 4, 2026 the Company announced that surface drilling has commenced at the Company's Rainbow Block Project in the Butte Mining District of Montana, marking the launch of its 2026 exploration program.   The 2026 program is designed to advance the Company's understanding of mineralization across the Rainbow Block and to support ongoing evaluation of priority silver, gold, zinc, and lead targets. The surface drill program is expected to include approximately 25,000 feet of drilling on Company private lands and test areas adjacent to the Company's previously announced Inferred Mineral Resource Estimate of approximately 170 million silver equivalent ounces at 14.8 oz/ton (or 4.28 oz/ton Ag, 0.05 oz/ton Au, 1.25% Pb, and 4.59% Zn).   * Barksdale Resources Corp. (TSXV: BRO) (OTCQB: BRKCF) (FSE: 2NZ) – On May 4, 2026 the Company announced assay results from the first four holes of the 2026 reverse circulation drill program on its flagship Sunnyside Project located in Arizona, USA. Assay results show several broad areas of shallow, high-grade copper-zinc-silver mineralization hosted within the Sunnyside Monzonite Porphyry.   Highlights include:   0.45% Cu over 392.19m from 3.05m to 396.24m in hole SUN26-002R including: 0.90% Cu over 60.96m from 173.74m to 234.70m 0.93% Cu over 60.96m from 265.18m to 326.14m Hole ended in mineralization 0.29% Cu over 454.15m from 3.05m to 457.20m in hole SUN26-001R including: 0.95% Cu over 39.63m from 248.41m to 288.04m Hole ended in mineralization   * Headwater Gold Inc. (CSE: HWG) (OTCQX: HWAUF) - On April 28, 2026, the Company announced results from the recent core drilling program at its TJ Project in Elko County, Nevada. The program was fully funded by OceanaGold Corporation (TSX: OGC, NYSE: OGC) pursuant to the earn-in agreement announced October 15, 2025.   Highlights: Highest gold grades to date: Core drilling returned grades up to 5.61 grams per tonne gold (“g/t Au”), confirming the presence of a high-grade epithermal vein system below the surface sinter.  Large, dynamic hydrothermal system confirmed: Drilling intersected 100 m thick hydrothermal breccia intervals, syn-mineral intrusions and multiple phases of epithermal veining across more than 500 metres of strike length. System open and expanding: Drilling has tested only a small portion of the system, but mineralization remains open at depth and along strike. The Company recently expanded the TJ land position by 88% (to 1,990 hectares) to cover the prospective northern continuation of the TJ graben.       * In full disclosure, some companies mentioned by Erik in this interview, are positions held in his personal portfolio, and also may be site sponsors of The Hedgeless Horseman website at the time of this recording.   Click here to follow Erik's analysis over at The Hedgeless Horseman website   For more market commentary & interview summaries, subscribe to our Substacks:   The KE Report: https://kereport.substack.com/ Shad's resource market commentary: https://excelsiorprosperity.substack.com/     Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned, and companies profiled may be sponsors of the KE Report.

In the final episode of this series, Dr. Justin Abbatemarco and Dr. Shreya Louis discuss the study results and their implications for improving clinical practice.  Read more about this abstract on the AAN website. 

In part two of this series, Dr. Justin Abbatemarco and Dr. Shreya Louis discuss how this technology was developed and how it has evolved.  Read more about this abstract on the AAN website. 

In this Company Update, I am joined by Mike Burke, Director and VP of Corporate Development at Sitka Gold (TSX.V: SIG | OTCQB: SITKF | FRA: 1RF). Mike provides a comprehensive breakdown of the newly analyzed tungsten data and how it integrates into the existing gold resource at the Rhosgobel gold deposit. We discuss the geological significance of these results, the potential for tungsten as a high-value by-product, and what this means for the project's future economics. Key Discussion Points: Tungsten Resource Potential: Mike discusses the re-sampling of 33 drill holes and the confirmation of tungsten mineralization over an 850-meter strike length. Metallurgical Synergy: An overview of how tungsten (in the form of scheelite) can be recovered using gravity and flotation - the same methods planned for the project's gold recovery. Critical Mineral Strategic Value: Insights into tungsten's status as a critical mineral and how its current high market price could impact the overall value of the RC Gold Project. 2026 Exploration Outlook: A look at the ongoing 60,000-meter drill program and the upcoming milestones.   If you have any follow up questions for the team at Sitka Gold please email me at Fleck@kereport.com.  Click here visit the Sitka Gold website to learn more about the Company - https://sitkagoldcorp.com/   --------------- For more market commentary & interview summaries, subscribe to our Substacks:  The KE Report: https://kereport.substack.com/  Shad's resource market commentary: https://excelsiorprosperity.substack.com/   Investment Disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security or investment product. Investing in equities, commodities, really everything involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

In the first part of this series, Dr. Justin Abbatemarco and Dr. Shreya Louis discuss the background and evolving terminology around circulating tumor DNA, cell‑free DNA and CSF‑based testing in neurology.  Read more about this abstract on the AAN website. 

Interview with Jeffrey R. Wilson, President & CEO of Precipitate Gold Corp.Our previous interview: https://www.cruxinvestor.com/posts/precipitate-gold-corp-tsxvprg-funding-secured-as-barrick-adjacent-drilling-starts-9454Recording date: 2nd April 2026Precipitate Gold Corp. (TSXV:PRG) is approaching what may be the most consequential period in its history. The Vancouver-based junior explorer holds three gold-copper projects in the Dominican Republic (all 100% owned) and is now executing on the phase of exploration that carries the highest potential for value creation: active discovery drilling.The company's two flagship assets are strategically located. Juan de Herrera shares a border with Goldquest Mining's Romero deposit, a 3.5 million gold-equivalent ounce resource advancing through feasibility and environmental review. Pueblo Grande surrounds Barrick Gold's Pueblo Viejo mine, one of the largest gold-producing operations in Latin America. In both cases, the host geology is known, the mineralisation style of high-grade gold and copper is confirmed in adjacent ground, and the question now is whether Precipitate's targets contain comparable mineralisation at economic grades.That question will be answered by the drill bit over the course of 2026. The company has planned up to 10,000 metres of drilling across multiple zones on both projects, with Pueblo Grande already in an active program and Juan de Herrera in final preparation for mobilisation. At Juan de Herrera, years of methodical exploration work of approximately 18,000 soil samples and subsequent induced polarisation geophysical surveys have identified multiple zones where elevated gold and copper at surface coincide with strong chargeability anomalies at depth. This is precisely the geochemical and geophysical signature that defines the Romero and Cachimbo mineralised zones on neighbouring Goldquest ground, lending the targeting approach a credible, data-driven foundation.The financial position supports the program without immediate dilution risk. A $6.5 million financing completed in January 2026, led by Dominican institutional investors, brought the total working capital to approximately $9 million. Those same investors hold approximately $5 million in in-the-money warrants, providing an additional funding lever should the drill program warrant expansion. The participation of locally connected Dominican capital is significant not only financially but as a signal: investors with direct knowledge of the political and regulatory environment have chosen to back the company at scale.The jurisdictional backdrop has improved meaningfully. The Dominican government has moved toward a more pro-mining stance, with faster permitting and demonstrated willingness to support projects through the development pipeline. Goldquest's advancement of Romero toward feasibility is providing the sector's first real proof of concept that the country can host a project from discovery through to production-ready status.From a valuation standpoint, Precipitate has historically traded in close ratio to Goldquest, despite Goldquest holding the established resource. That relationship has diverged over the past two years as Goldquest re-rated on the back of jurisdictional improvements and project advancement. Management believes the gap represents an opportunity, with exploration success at Juan de Herrera or Pueblo Grande the most direct mechanism to close it.Assay results from both projects, expected progressively across 2026, will define the investment outcome. For investors with the risk tolerance appropriate to early-stage exploration, the current setup in terms of geological, financial, and jurisdictional is as well-structured as Precipitate has ever presented.View Precipitate Gold's company profile: https://www.cruxinvestor.com/companies/precipitate-gold-corpSign up for Crux Investor: https://cruxinvestor.com

Interview with Steven Sirbovan, President & CEO of ICG Silver & GoldRecording date: 1st April 2026ICG Silver and Gold Corp. is a newly listed exploration company that began trading on the CSE on March 31, 2026, after spinning out from American Pacific Mining. The company holds a single flagship asset, the Tuscarora District, a 10,000-acre contiguous land package in northeastern Nevada positioned at the intersection of the Independence and Carlin Trends. For investors evaluating the junior exploration space, ICG presents a clearly defined near-term catalyst, a funded treasury, and a geological thesis that differentiates it from prior operators at the same project.The Tuscarora District is not a greenfield exploration play. Historical operators Novo Resources and American Pacific Mining conducted 25,000 metres of drilling, collected 5,000 samples, and completed 130 line-kilometres of geophysics across the property. Those programs generated high-grade results, including an intersection of just over 4 metres grading 127 g/t gold at the South Navajo target. Despite this work, the project was consistently treated as a gold-only system. ICG's management believes that interpretation left a significant dimension of the project unexplored: a spatially overlapping, silver-dominant epithermal system, supported by surface rock samples returning up to approximately 38,000 g/t silver at certain targets and near-surface geophysical anomalies.The former Dexter open-pit mine, located just off the property boundary on trend with the South Navajo and Modoc targets, produced approximately 50,000 ounces of gold and 250,000 ounces of silver in the early 1990s and serves as a direct analogue for the style of mineralisation management is targeting.The company enters the market with approximately C$6.2 million in the treasury and a Phase 1 RC drill program of 3,000 to 6,000 metres scheduled to commence in June 2026. RC costs in the region are currently estimated at approximately US$250 per metre, providing ICG with sufficient capital to complete the program without near-term financing pressure. Assay results are expected in August 2026, giving investors a defined newsflow window within the current calendar year.The Phase 1 program targets two categories of drill holes. The first group focuses on South Navajo and Modoc to build toward an eventual mineral resource. The second and more exploration-oriented group targets East Pediment, Grand Prize, King's Vein, and North Navajo areas which are identified through sampling and geophysics but not yet systematically drilled. Hole depths are planned at 200 to 300 metres, consistent with the shallow, open-pittable mineralisation model the company is evaluating.The management team brings relevant capital markets and technical depth. CEO Steven Sirbovan has 13 years of capital markets experience including work at Waterton Global Resource Management with a Nevada focus. The board includes Jeff Swinoga, formerly of Barrick Gold, and Gary Baschuk, who spent significant time at Barrick's Goldstrike operation in Nevada. VP of Exploration Korbon McCall provides direct technical continuity with the project through his prior work with American Pacific.For investors, the near-term thesis is straightforward: a funded drill program, an August 2026 assay window, and a geological interpretation that has not previously been tested at district scale. The key risk, as with any early-stage exploration company, is that drilling results may not confirm the dual-system thesis. Investors should size positions accordingly and monitor Phase 1 results as the primary near-term value inflection point.Learn more: https://cruxinvestor.comSign up for Crux Investor: https://cruxinvestor.com

Diagnostic laboratories are a key part of the veterinary care team, but one most…

Diagnostic laboratories are a key part of the veterinary care team, but one most people don't commonly interact with. Dr. Michael Dark, clinical associate professor and director of UF's veterinary...

Interview with Tara Christie, President & CEO of Banyan Gold Corp.Our previous interview: https://www.cruxinvestor.com/posts/banyan-gold-tsxvbyn-76moz-gold-project-advances-toward-2026-pea-8866Recording date: 1st March 2026Banyan Gold Corp. (TSXV:BYN) enters 2026 as one of the more substantive junior gold development stories in Canada's Yukon Territory. With a 7.7-million-ounce gold resource at its AurMac project, a fully funded 40,000-metre drill program underway, and a maiden Preliminary Economic Assessment scheduled for the second half of the year, the company has a clear and near-term catalyst pipeline.The 2025 drill program of approximately 43,000 metres targeted two high-grade zones—Airstrip and Powerline—which are expected to anchor the starter pit economics in the upcoming PEA. Intercepts of 16 metres at 9 g/t and 40 metres at 4 g/t at Airstrip, and multiple 2–3 metre intervals at 16 g/t at Powerline, represent above-average grades relative to the broader deposit. Assay results from the full 2025 campaign remain pending, with a resource update to follow. Step-out drilling has extended the deposit's surface expression by approximately one kilometre in both directions along Airstrip, reinforcing management's view that AurMac is a substantially larger system than legacy models indicated.A separate high-grade silver discovery—18 drill hits across six shallow veins, with grades exceeding 13,000 g/t at depths as shallow as 65 metres—adds a layer of optionality not yet captured in any economic study. The most significant external data point for valuing AurMac is Franco-Nevada's February 2026 acquisition of the project royalty for $52.2 million. The royalty carries a buydown provision reducing it to 1% for $10 million—meaning Franco-Nevada effectively paid approximately $42 million for a 1% net smelter royalty. At Banyan's current market capitalisation, this implies the equity market is ascribing a fraction of the value to the full project that a leading royalty company paid for just one percent of it. That gap is the central valuation argument for the stock.Despite a share price increase of approximately 350% in 2025, Banyan trades at under US$50 per ounce of resource. Yukon development peers trade at US$60 to US$300 per ounce. Christie noted that comparable companies were achieving the US$50/oz valuation at US$1,800 gold—implying the current per-ounce value has not kept pace with the commodity. Three investor misconceptions resolved in October 2025—heap leach versus mill, legacy shareholding overhang, and partial property ownership—had suppressed the stock relative to peers and have now been corrected.Execution risk is reduced by full funding secured in October 2025, an early season start with five drills operating by mid-March, and contracts with senior field personnel signed ahead of competitors. The company is not seeking additional capital and is focused on delivering value from existing resources.The PEA in H2 2026 is the defining event. It will establish the first public economic framework for AurMac and provide the foundation for any subsequent corporate transaction, partnership, or development financing discussion. For investors positioned ahead of that catalyst, the combination of resource scale, jurisdictional quality, external royalty validation, and a measurable per-ounce discount to peers represents a specific and trackable investment case.View Banyan Gold's company profile: https://www.cruxinvestor.com/companies/banyan-gold-incSign up for Crux Investor: https://cruxinvestor.com

Design for Security from the Start: Making Medical Device Cybersecurity More ResilientMedTech innovation is revolutionizing healthcare but is also introducing new cyberattack vectors that can put manufacturers, hospitals, and patients at risk.In Episode 44 of the MedTech Speed to Data Podcast, Key Tech VP of Business Development Andy Rogers and Senior Computer Engineer Jamie Kendall discuss the FDA's latest cybersecurity guidance.Need to knowSmart, connected devices have greater risks — Medical devices are emerging vectors for bad actors targeting the healthcare industry.FDA's 2025 cybersecurity guidance update — The agency recommends risk-based development frameworks to make device cybersecurity more resilient.Clarifying “cyber devices” — The FDA's guidance applies to any medical device that runs software and could connect to the Internet.The nitty-gritty“Cybersecurity was always baked into our process,” Jaime explains. More specifically, Key Tech has adapted the TIR57 risk-based standard for managing medical device security to the new rules. “[The FDA's] 2023 guidance really laid the groundwork for our latest process. We've tweaked it slightly with the [latest update]. There are more explicit documentation requirements around vulnerability monitoring and more details on the software bill of materials (SBOMs).”Jamie goes on to describe how Key Tech's cybersecurity risk management plan informs product development. The security team starts by developing a threat model based on evaluations of data flows, data storage, and the cybersecurity activities protecting that data. “One of the first things that we always do is a threat model. This is a visual model of the system to show the elements of the device, where data is flowing, and where your trust boundaries are. This is a one-page, digestible visual that everyone can look at, assess, and go ‘yep, that makes sense' and then build your initial architecture and risk assessment based on that.”The security team documents the resulting security architectures using the FDA's recommended views:Global System View: Describes how software integrates with hardware and networks and the associated cybersecurity mitigations.Multi-Patient Harm View: Identifies mitigations for vulnerabilities or failures that could compromise multiple devices and harm multiple patients.Updateability/Patchability View: Summarizes the end-to-end process for distributing software updates and patches, especially if manufacturers do not control the entire path.Security Use Case View: Documents scenarios in which vulnerabilities can compromise the device's safety or effectiveness.“To give a sense of scale,” Jamie says, “this isn't one or two documents. It's a pretty large effort, and it's one of those things that you want to start early in your development process.”Data that made the difference:Throughout his conversation with Andy, Jamie shares some of the lessons Key Tech has learned about designing secure medical devices, including:Design for security from the beginning. Late changes are expensive, especially once in pre-production or after your FDA submission.Avoid cyber rabbit holes. Rather than addressing every possible threat, use data and risk to prioritize the real threats.Don't roll your own cybersecurity. Stick to standard practices, or you risk introducing unknown, novel vulnerabilities.Fully document your SBOMs. Standard libraries introduce layers of dependencies that you must understand. That's the only way to control your exposure to new vulnerabilities.Design devices that are truly safe. Cybersecurity risks are real. Don't treat compliance as a check box.Watch the whole conversation in the video below to learn more about designing for cybersecurity, the importance of third-party penetration testing, and more.

Roger Rosmus, Founder, CEO, & Director of Goliath Resources (TSX.V: GOT) (OTCQB: GOTRF), joins us live from the AME Roundup to highlight the positive investor sentiment after attending 3 back-to-back Vancouver resource conferences.  Additionally, we dig into recent news released on the final 70 gold-only drill hole assays returned from last year's program, the pending assays for 110 multi-element results on all the 2025 drill holes, along with a number of corporate initiatives around not doing a share consolidation, on buying back the NSR from 3% down to 2%, and on fast-tracking its ownership in the Golddigger Property located in the Golden Triangle, B.C. that hosts the high-grade Surebet gold discovery from 49% to 100%.   Drill hole GD-25-319 intersected 19.13 g/t Au over 6.10 meters, including 22.86 g/t Au over 5.10 meters, including 29.09 g/t Au over 4.00 meters in quartz-sulphide veins, part of the Golden Gate Zone Assays are still pending for 110 drill holes from 2025 for multi-element gold equivalent (AuEq) results. These results will be released in the near future once all assays have been received, compiled and interpreted. 100% of the drill holes completed to date, have all intersected gold mineralization clearly demonstrating the remarkable continuity, grades, and widths in 5 Main Gold-Rich Zones comprising 46 mineralized lodes that remain open for expansion. Of the holes drilled during the 2025 campaign, 83 out of 110 holes (or 76%) contained visible gold to the naked eye (VG-NE). The fully funded 2026 drill program will be mainly focused on expanding the 5 Main Mineralized Zones. Data compilation and interpretation is underway which will be used to vector in on the indicated Motherlode causative intrusive source to this extensive high grade gold system with widespread VG-NE.     As part of the transaction to J2 Syndicate Holdings Ltd. to acquire 100% ownership in the Golddigger Property, that Goliath is now set to publish a Maiden Resource Estimate (MRE) on the Golddigger Property before June, 1 2030 and on every 3 year anniversary of June 1,2030 thereafter vs. the prior requirement, in the original agreement, to publish the MRE by June 1, 2027.    Roger outlines the Company's rationale that it makes far more sense to keep expanding the mineralization with aggressive exploration programs, versus trying to pin down the MRE at this stage. He provides both positive examples of companies that have taken this route, versus the negative examples of companies that rushed to put out a MRE, only to fence themselves in with regards to valuations and market perceptions.   Wrapping up, we reviewed that in December cornerstone investors Rob McEwen and Crescat Capital increased their stakes in the company, as well as discussing the optionality that Goliath has with regards to their equity holdings of McEwen Inc shares which have essentially gone up about 3X since acquiring them.  In addition to future conversion of warrants from Rob McEwen, the (MUX) shares provide the option for more capital inflows into the company treasury to fund more exploration.   If you have any questions for Roger about Goliath Resources, then please email us at Fleck@kereport.com or Shad@kereport.com.     In full disclosure, Shad is a shareholder of Goliath Resources at the time of this recording and may choose to buy or sell shares at any time.   Click here to follow the latest news from Goliath Resources   For more market commentary & interview summaries, subscribe to our Substacks:   The KE Report: https://kereport.substack.com/ Shad's resource market commentary: https://excelsiorprosperity.substack.com/     Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.

Interview with Gordon Neal, President, Domestic Metals Recording date: 9th December 2025Domestic Metals has acquired a promising Montana copper porphyry project from Rio Tinto through an earn-in agreement that highlights the property's significant potential. The company can earn 60% ownership by spending $3.15 million USD on exploration work, with Rio Tinto retaining 40% plus an unusual 20% clawback provision—a protective measure that underscores the major miner's conviction in the project's long-term value.The Smart Creek-Sunrise property occupies compelling geological ground, located 50 kilometers northwest of the historic Butte mine, which has produced 22 billion pounds of copper over a century. The project sits within the same Helena formation geology, with company geologists noting that rocks match Butte's characteristics in age and composition. Rio Tinto drilled 26 of 40 total holes on the property, with results improving progressively from southeast to northwest. The best intercept to date shows 109 meters at 0.75% copper, including 80 meters at 0.97% copper, suggesting drilling was advancing toward rather than away from the porphyry center.President Gordon Neal brings proven credentials, having built MAG Silver from $50 million to $2.5 billion market capitalization and New Pacific Metals from $100 million to $1.5 billion. His track record in capital markets and project development provides credibility to the company's exploration strategy.The company recently raised $4 million to fund comprehensive IP and magnetotelluric geophysical surveys in January-February 2026, followed by 3,000+ meters of drilling starting February-March. Assay results are expected April-May 2026. A critical advantage is Montana's streamlined permitting environment, with drill permits obtained in four months versus 5-7 years in Arizona. The Forest Service recently extended 36 expired drill permits using existing paperwork—unprecedented flexibility that enables rapid, capital-efficient advancement of what could become a significant domestic copper discovery.Sign up for Crux Investor: https://cruxinvestor.com

HSBC Innovations is the global bank's financing arm for American and European startups, especially in the healthcare and life sciences industries. The bank's semi-annual Venture Healthcare Reports document trends in the investment market.Key Tech's Andy Rogers welcomes the report's author, HSBC Innovation Managing Director Jon Norris in Episode 43 of the MedTech Speed to Data podcast.Need to know·       Four core market segments — HSBC Innovation's Venture Healthcare Reports cover investments and exits in Biopharma, Dx/Tools, Med Device, and Healthtech.·       Sourcing investment data — Norris enriches Pitchbook data with additional structure and analyses, making the report more relevant to these market segments.·       Sourcing exit data — Norris supplements media and industry publications with market research and conversations with industry leaders.·       An investment data tapestry — The reports provide “an honest picture of what's going on in the market” so investors and innovators alike “can make targeted smart decisions.”The nitty-grittyAndy and Norris discuss the investment market's recent history before exploring drivers of today's investment headwinds.“2021 was a record-setting year,” Norris recalls. “Every record that could be set for deals and dollars was set across all the sectors.” Things changed in 2022 as new BioTech IPOs struggled, prompting investment reprioritizations.“VCs had done all these… frothy valuations,” Norris says. “They had to go back and look at their own portfolios and say, does this company have enough capital? How do you want to put money to work?”Investments rebounded in 2024, but not the number of deals. Investors poured money into their existing portfolios to boost their exit chances, resulting in today's nine-figure megadeals.“Basically, they're smooshing two rounds together and extending the investors coming in to support that round,” Norris says.Headwinds stiffened in 2025 as tariffs, a more litigious competitive space, and other factors amplified business uncertainty.Norris attributes this progression to the psychology of venture capital. “When you think about what makes these folks tick,” Norris explains, “they want to continue to raise new venture funds because they get paid management fees. But in order to raise their new venture funds, they have to show their investors that they've actually gotten returns.”That means reaching an acquisition or IPO. “They're very focused on getting to exit right now. That's why they're so focused on their existing portfolio. And because of that, they haven't been doing as many new investments.”New investments still happen, of course, but the criteria have changed. “While the dollars are actually up in some of these sectors, especially Med Device,” Norris says, “you're seeing that being put to work on later-stage deals because they'd rather get a shorter time to exit.”Data that made the difference:Norris' insights from the HSBC Venture Healthcare Report let him advise startups fighting today's investment headwinds.Adopt a megaround mentality. “Series B has been extremely difficult,” Norris says. “[Raising] sub two million, that's one thing. But if you're looking to raise five million, it's almost better to raise twelve.”Find investors outside the mainstream. “Traditional venture investors don't want to write small checks.” Norris sees angel groups, innovation centers, and other small investors funding these early rounds.Explore acquisition exits, but be careful. “On the device side, most of the corporates have been pretty darn active,” Norris says. However, some litigate to block emerging competition, especially in the Dx/Tools sector. Norris' recommends researching potential acquirers before taking meetings.Download the HSBC Venture Healthcare Report for Norris' complete analysis, and watch the video below for insights into the Medical Device and Dx/Tools sectors, AI's role in MedTech, and more.

Nuclear Proliferation Concerns Regarding Small Modular Reactors and Weapons Testing. Henry Sokolski raises proliferation concerns about Small Modular Reactors (SMRs) using High-Assay Low-Enriched Uranium (HALEU) fuel (20% enriched). Declassified cables from 1954 and 1977 suggested that uranium above 10% requires special concern, demanding a review before SMRs are exported. Sokolski also clarifies that US maintenance of its nuclear arsenal relies on non-critical tests and simulations, not full-yield explosions, though adversaries may be conducting critical tests.

Nuclear Proliferation Concerns Regarding Small Modular Reactors and Weapons Testing. Henry Sokolski raises proliferation concerns about Small Modular Reactors (SMRs) using High-Assay Low-Enriched Uranium (HALEU) fuel (20% enriched). Declassified cables from 1954 and 1977 suggested that uranium above 10% requires special concern, demanding a review before SMRs are exported. Sokolski also clarifies that US maintenance of its nuclear arsenal relies on non-critical tests and simulations, not full-yield explosions, though adversaries may be conducting critical tests.