Podcasts about envigo

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Best podcasts about envigo

Latest podcast episodes about envigo

The Dr. Peter Breggin Hour
Dr. Peter Breggin Hour - 5-27-26

The Dr. Peter Breggin Hour

Play Episode Listen Later May 27, 2026 57:00


In early May 2026, transport vans rolled out of Ridglan Farms in Blue Mounds, Wisconsin, carrying beagles toward new lives—grass under their paws, sunlight on their faces, and homes instead of stacked wire cages. Nearly 1,500 beagles were purchased by rescue organizations like Big Dog Ranch Rescue and the Beagle Freedom Project after years of documented suffering at one of the nation's largest commercial beagle breeders for biomedical research. This outcome marks a rare, tangible win for animal advocates. But it came only after daring direct-action raids, mass protests met with tear gas and rubber bullets, a special prosecutor's investigation, and persistent legal pressure. Even now, roughly 500 dogs may remain behind as Ridglan winds down its commercial breeding operations by July 1, 2026. The Ridglan story is not just about one facility. It exposes deep, systemic failures in U.S. law that leave millions of animals in laboratories with minimal protections—and even those “covered” by federal rules often receive little meaningful relief. The Raids That Forced Change On March 15, 2026, activists from groups linked to the Coalition to Save the Ridglan Dogs breached fences and buildings at Ridglan Farms. They removed around 22–30 beagles. Some were successfully rehomed; others were recovered by police. However, an estimated 2000 beagles remained in captivity, potentially subject to additional horrific experimentation. Our guest, Dean Guzman Wyrzykowski, was one of these activists. A second, larger action on April 18 drew roughly 1,000 protesters to rescue the remaining beagles. Law enforcement responded with tear gas, pepper spray, and rubber bullets. No additional dogs could be rescued that day. Dozens of protesters were arrested, including our guest on The Breggin Hour, Dean Guzman Wyrzykowski, a San Francisco Bay Area-based animal rights activist and political organizer. He is co-founder of The Simple Heart Initiative—a nonprofit dedicated to advancing species equality through open rescue, impact litigation, undercover investigations, and activist training. With over eight years in nonprofit advocacy, Dean has recruited and trained hundreds of activists and is one of the lead organizers of the Ridglan campaign. He now faces serious felony burglary charges—potentially up to 12 years in prison—along with several co-defendants for the first March 15, 2026, rescue effort. Further charges may be pending. As a top priority, we urge that the charges be reduced or dropped to reflect the vastly important ethical basis of the actions of these animal advocates. How to Help Dean Dean reports that the best way to assist him with legal costs is to become a paid subscriber to his Substack at Urbananimal.substack.com. To support ending the breeding of dogs for lab testing, go to Save the Dogs, make a donation, and join over 111,581 others who have already signed the petition to end breeding of dogs for laboratory use. These weren't the first efforts to expose and stop the abuses of these dogs. Ridglan had faced scrutiny for years, including earlier investigations. The raids amplified public outrage and accelerated negotiations between rescuers and Ridglan Farms. In late April, rescue groups announced they had reached a deal to acquire ~1,500 dogs. Transports began in early May, with many “frosted face” seniors (older dogs with graying muzzles) now adjusting to life outside the facility—initially flinching at touch but quickly learning to wag tails and play. Decades of Alleged Cruelty at Ridglan — and Why It Is Winding Down Ridglan Farms operated for decades as a major supplier of beagles for testing. Former employees and state inspections described windowless warehouses, stacked cages over waste pits, high ammonia levels, rusted wires causing injuries, and routine surgeries (including eye procedures and devocalizations) performed without anesthesia or proper pain relief—sometimes by non-veterinarians. In 2025, Wisconsin's Department of Agriculture, Trade and Consumer Protection (DATCP) cited Ridglan for hundreds of violations. A judge found probable cause for animal cruelty. Special Prosecutor Tim Gruenke was appointed to investigate. Rather than face criminal charges, Ridglan chose to wind down. In a negotiated settlement in late 2025, the company agreed to surrender its Wisconsin commercial dog-breeding license by July 1, 2026. This effectively ends its large-scale commercial breeding and sales of beagles to external laboratories. In exchange, the state dropped the threat of felony animal cruelty prosecutions. This agreement was driven by years of accumulated citations, whistleblower testimony, undercover investigations, and intense public and activist pressure. While Ridglan can still conduct limited on-site research under its federal USDA licenses, its days as a major commercial beagle supplier are over. Parallels with Envigo and Other Scandals Ridglan is far from isolated. In 2022, a major scandal erupted at Envigo's breeding facility in Cumberland, Virginia. PETA's undercover investigation revealed severe neglect: inadequate food, veterinary care, housing, and staffing; dead puppies were left among litters; and unqualified staff performed invasive procedures. The U.S. Department of Justice intervened, leading to the rescue of over 4,000 beagles—the largest such seizure in U.S. history. Envigo (and its parent company Inotiv) later pleaded guilty to conspiring to violate the Animal Welfare Act and the Clean Water Act, agreeing to pay a record $35 million+ in fines and shutting down the breeding operation. From the Beagles to the Breggins, Senator Bill Stanley Sought Justice for the Underdog At a state level, key Virginia state legislators were involved in advocating for stronger animal welfare regulations in response to documented Animal Welfare Act violations, poor conditions, and high puppy mortality in the facility. Sen. Bill Stanley (R-Franklin County) was a leading champion at the state level. He visited the facility multiple times, co-sponsored several “Beagle Bills” in 2022 (e.g., SB 87, SB 88, SB 90, SB 604) to increase oversight, close loopholes for research animals, require adoption offers before euthanasia, and penalize repeat violators. He adopted two Envigo beagles (Daisy and Dixie) and worked on adoptions/rescues. We are especially happy to acknowledge Sen. Stanley's contributions because, among several attorneys we contacted to defend us against Robert Malone's lawfare defamation suit against us for $25 million, Bill was the first attorney willing to seriously pursue our case, which ended in the presiding judge throwing Malone's case out of court. From the beagles to the Breggins, Senator Stanley has sought justice for the underdog. The Sand Fly Experiments and High-Profile Scandals Public outrage over government-funded beagle suffering peaked in the early 2020s with revelations about NIH-funded experiments under Dr. Anthony Fauci's National Institute of Allergy and Infectious Diseases (NIAID). One widely criticized study involved beagle puppies in Tunisia exposed to sand flies carrying parasites (to study leishmaniasis). Reports described dogs having their heads locked in mesh cages filled with infected sand flies, being used as live bait in desert cages overnight, and in some cases undergoing cordectomies (vocal cord removal) to silence barking. The experiments sparked bipartisan congressional criticism and intense media coverage. The Nonhuman Rights Project (NhRP) and partners filed habeas corpus petitions seeking court recognition of the Ridglan dogs' right to freedom from cruelty and immediate remedies. While initial petitions faced dismissal, appeals continue for the remaining animals. Why U.S. Law Fails Experimental Animals The core federal statute is the Animal Welfare Act (AWA) of 1966 (and its amendments), enforced by the USDA's Animal and Plant Health Inspection Service (APHIS). It sets minimum standards for housing, feeding, veterinary care, and handling of certain animals. Critical Limitations Include: Massive Species Exclusions: Rats, mice, and birds bred for research—accounting for roughly 95% of lab animals—are explicitly excluded. Cold-blooded animals and others also fall outside coverage. Weak Standards for Covered Species: Even for dogs, cats, primates, etc., the AWA permits painful procedures if deemed “scientifically necessary.” There is no outright ban on specific types of experiments. Self-Regulation via IACUCs: Institutional Animal Care and Use Committees—dominated by researchers at the institutions they oversee—review protocols. Approval rates hover near 98%, with limited external oversight. Enforcement Gaps: Under-resourced inspections, reliance on self-reporting, and modest penalties limit impact. Ridglan itself had passed many USDA inspections despite state-level findings of serious issues. Property Status: Animals remain legal property. Novel habeas efforts like the Nonhuman Rights Project (NhRP) challenge this but face significant judicial hurdles, as courts have historically rejected animal “personhood” claims. For those of us who learned in childhood about unconditional love from our dogs, they are not only of equal value to people, but they seem on a higher spiritual level in the love they have given to us. Other frameworks, such as the Public Health Service Policy, apply only to federally funded research and offer even less robust enforcement. The 2022 FDA Modernization Act opened doors to non-animal alternatives, but broader statutory mandates for the “3Rs” (Replacement, Reduction, Refinement) remain limited. Reform efforts often stall due to powerful research lobbies, congressional agriculture committees' oversight, and public support for medical research that can overshadow welfare concerns. Broader Context and the Path Forward Ridglan and Envigo show that systemic problems persist despite occasional rescues and fines. Millions of animals continue to be used annually in U.S. labs, yet positive developments exist: growing adoption of alternatives (organ-on-chip, AI modeling, human cell cultures), increased rehoming programs, and shifting public opinion favoring stronger protections. The Ridglan victory shows that sustained pressure—investigations, lawsuits, public protest, and direct rescue—can force change where law falls short. Yet relying on activists risking felony charges is not sustainable. Meaningful reform requires: Expanding Animal Welfare Act coverage to all vertebrates. Stronger, independent oversight and enforcement with real penalties. Mandatory consideration and funding for non-animal methods. Judicial tools (like effective habeas relief) to address cruelty in licensed facilities promptly. A Call to Readers The beagles now tasting freedom represent hope—but hundreds may still face uncertainty, and systemic issues persist for countless others. Share their stories. Support reputable rescues and organizations like The Simple Heart Initiative, the Nonhuman Rights Project, Beagle Freedom Project, and others working on legal and legislative fronts. Contact your representatives and demand real modernization of the Animal Welfare Act. Persistence works. Now we must translate outrage into lasting legal change—so no more facilities like this exist in the first place. What are your thoughts on balancing research needs with animal welfare? Have you followed the Ridglan story, the Envigo case, Dean's work, or the earlier sand fly scandals? Drop a comment or share this post. References / Endnotes Wisconsin Examiner / Milwaukee Journal Sentinel coverage of Ridglan rescues and settlement (2026). Nonhuman Rights Project – Ridglan Beagles case page. U.S. Department of Justice – Envigo sentencing and $35M+ resolution (2024). Bipartisan congressional letters on NIAID/Tunisia sand fly experiments (2021). Dean Guzman Wyrzykowski / The Simple Heart Initiative statements (2026). USDA Animal Welfare Act overview and limitations. Additional reporting from WPR, Right to Rescue, and related investigations.   ______   Learn more about Dr. Peter Breggin's work: https://breggin.com/   See more from Dr. Breggin's long history of being a reformer in psychiatry: https://breggin.com/Psychiatry-as-an-Instrument-of-Social-and-Political-Control   Psychiatric Drug Withdrawal, the how-to manual @ https://breggin.com/a-guide-for-prescribers-therapists-patients-and-their-families/   Get a copy of Dr. Breggin's latest book: WHO ARE THE “THEY” - THESE GLOBAL PREDATORS? WHAT ARE THEIR MOTIVES AND THEIR PLANS FOR US? HOW CAN WE DEFEND AGAINST THEM? Covid-19 and the Global Predators: We are the Prey Get a copy: https://www.wearetheprey.com/   “No other book so comprehensively covers the details of COVID-19 criminal conduct as well as its origins in a network of global predators seeking wealth and power at the expense of human freedom and prosperity, under cover of false public health policies.”   ~ Robert F Kennedy, Jr Author of #1 bestseller The Real Anthony Fauci and Founder, Chairman and Chief Legal Counsel for Children's Health Defense.

LIVIN THE GOOD LIFE SHOW
Brian Fleming, Club Direct (BSN SPORTS)

LIVIN THE GOOD LIFE SHOW

Play Episode Listen Later Nov 12, 2025 9:59


BSN SPORTS commissioned The Club Sports Index, a first-of-kind national study in October 2025 to get a snapshot of the current club sports landscape in the United States. The Club Sports Index surveyed 2,000 athletes, 2,000 parents and 150 club owners across a spectrum of topics, including:Motivations for participating in club sportsTime commitment involved for both athletes and parentsCost associated with participationLong term goals for club athletesPopularity of specific sports by regionBrian Fleming is the Senior Vice President and General Manager of Club Direct for BSN SPORTS, a division of Varsity Brands, where he leads commercial strategy and overall execution to grow and service the market segment. He joined BSN SPORTS in 2022 following a successful tenure as General Manager of the Collegiate & Commercial divisions at Herff Jones, where he oversaw a $100+ million business and drove revenue growth across multiple verticals. Prior to that, he held global finance leadership roles at Firestone Industrial Products and Envigo, as well as an early career in Public Accounting, Business Valuation and Management Consulting. A Certified Public Accountant, Brian earned his MBA in Finance and Operations Management from Valparaiso University. 

Species Unite
Melanie Kaplan: Lab Dog

Species Unite

Play Episode Listen Later Oct 22, 2025 40:01


“Maybe when we started doing this with animals, researching on them and studying them for human benefit hundreds of years ago, we didn't know about their sentience. We didn't know that they had emotions and feelings and felt pain. And we know all that now. We can't ignore that.” – Melanie Kaplan When journalist Melanie Kaplan agreed to foster a beagle named Hammy, she knew he'd just been released from a research lab. What she didn't know was how profoundly his story — and the world he came from — would change her own. In her new book, Lab Dog: A Beagle and His Human Investigate the Surprising World of Animal Research, Melanie takes readers deep inside the hidden world of animal testing — one that quietly breeds and experiments on tens of thousands of dogs each year, mostly beagles, chosen for their size and gentle nature. Through her journey with Hammy, she unravels how these animals end up in labs, what happens to them there, and what it takes to help them heal once they're free. Our conversation explores the long and often secretive history of animal testing in the U.S., the shocking revelations behind the Envigo case — where 4,000 beagles were rescued from a breeding facility in Virginia — and the growing movement toward humane, non-animal alternatives. Links:  Melanie Kaplan: https://melaniedgkaplan.com/index.html Lab Dog: https://www.hachettebookgroup.com/titles/melanie-d-g-kaplan/lab-dog/9781541604988/

Ash Said It® Daily
Episode 2044 - RedRover President & CEO Katie Campbell

Ash Said It® Daily

Play Episode Listen Later Feb 1, 2025 13:58


Katie Campbell is the President and CEO of RedRover, a national animal welfare nonprofit organization based in Sacramento, California. Campbell assumed this role in March 2024. Campbell has been with RedRover for eight years, previously serving as the Director of Collaboration and Outreach. In this role, she supported the organization's outreach, awareness, and capacity-building efforts, particularly for their domestic violence assistance programs. She is passionate about animal welfare and has a strong background in the nonprofit sector. Campbell holds a Bachelor of Science degree in Sociology and Criminal Justice from Lees-McRae College and a Master of Arts degree in Sociology from California State University, Sacramento. Since 1987, RedRover has been a lifeline for animals in need. As a national animal welfare nonprofit, we're there for animals during emergencies, disasters, and times of crisis. Our three programs work together to provide comprehensive support: RedRover Relief offers grants for emergency veterinary care, including the Safe Housing and Purple Leash Project, which helps domestic violence survivors and their pets escape abusive situations. RedRover Responders, known as the "Red Cross for animals," deploys to disaster zones and rescues animals from puppy mills and hoarding cases. And through RedRover Readers, we're teaching the next generation about compassion and empathy. Join us to learn more about how RedRover is making a real difference for animals across the US and Canada. Web: https://redrover.org/ Mission: Our mission is to bring animals out of crisis and strengthen the bond between people and animals through emergency sheltering, disaster-relief services, financial assistance, and education. We accomplish this by engaging volunteers and supporters, collaborating with others, and maximizing the use of online technology. RedRover Relief: Offers pet parents grants and resources for animals in need of emergency veterinary care. Through this program, Safe Housing & Purple Leash Project (sponsored by Purina) grants also help domestic violence (DV) survivors escape abuse with their pets. Since 2012, RedRover has awarded 237 Safe Housing grants to shelters in 47 states, totaling more than $5.2 million. Additionally, Safe Housing grants have created the first pet-friendly domestic violence shelters in 10 states! We also created a collaborative project with Greater Good Charities' Rescue Rebuild program, called Dontforgetthepets.org (DFTP). This program helps domestic violence, homeless, and animal shelters create custom pet housing programs to fit the needs of their communities - everything from design and construction to policies and procedures. RedRover Responders: Known as the "Red Cross for animals," we temporarily shelter and care for animals displaced by natural disasters or animals rescued from puppy mills and hoarding cases. RedRover has deployed 280+ times since 1987, including to the Envigo beagle rescue, Hurricanes Katrina, Harvey, Ian, Superstorm Sandy, Camp and Caldor wildfires, Northridge earthquake, and many more. RedRover Readers: Helps children understand the emotional states of others and develop the skills needed for empathy to prevent animal cruelty and neglect. The program has reached more than 100,000 children. Publishes Kind News magazine for children - helping kids understand and respect animals. About the show: Ash Brown is a force to be reckoned with in the world of motivation and empowerment. This multi-talented American is a gifted producer, blogger, speaker, media personality, and event emcee. Her infectious energy and passion for helping others shine through in everything she does. Ash Said It, Ash Does It: * AshSaidit.com: This vibrant blog is your one-stop shop for a peek into Ash's world. Dive into exclusive event invites, insightful product reviews, and a whole lot more. It's a platform that keeps you informed and entertained. * The Ash Said It Show: Buckle up for a motivational ride with Ash's signature podcast. With over 2,000 episodesalready under her belt and a staggering half a million streams worldwide, this show is a testament to Ash's impact. Here, she chats with inspiring individuals and tackles topics that resonate deeply. What Makes Ash Special? Ash doesn't just preach motivation; she lives it. Her strength lies in her authenticity. She connects with her audience on a genuine level, offering real-talk advice and encouragement. She doesn't shy away from the challenges life throws our way, but instead, equips you with the tools to overcome them. Here's what sets Ash apart: * Unwavering Positivity: Ash Brown is a glass-half-full kind of person. Her infectious optimism is contagious, leaving you feeling empowered and ready to take on the world. * Real & Relatable: Ash doesn't sugarcoat things. She understands the struggles we face and offers relatable advice that resonates with listeners from all walks of life. * Actionable Strategies: This isn't just about empty inspirational quotes. Ash provides practical tips and strategies to help you translate motivation into action, turning your dreams into reality. So, if you're looking for a daily dose of inspiration, actionable advice, and a healthy dose of real talk, look no further than Ash Brown. With her infectious positivity and dedication to empowering others, she's sure to become your go-to source for making the most of life. ► Goli Gummy Discounts Link: https://go.goli.com/1loveash5 ► Luxury Women Handbag Discounts: https://www.theofficialathena.... ► Review Us: https://itunes.apple.com/us/po... ► Subscribe: http://www.youtube.com/c/AshSa... ► Instagram: https://www.instagram.com/1lov... ► Facebook: https://www.facebook.com/ashsa... ► Blog: http://www.ashsaidit.com/blog #atlanta #ashsaidit #theashsaiditshow #ashblogsit #ashsaidit®Become a supporter of this podcast: https://www.spreaker.com/podcast/the-ash-said-it-show--1213325/support.

Hard Factor
Crime-spree-international-U.S.-mercenary-muder-soldiers | 6.6.24

Hard Factor

Play Episode Listen Later Jun 6, 2024 40:50


In Episode 1477, Craig Austin Lang and Alex Jared Zwiefelhofer, two U.S. soldiers went on an insane crime-murder-mercernary-coup-spree and the details are just too strange. Also, a juror was dismissed Monday after reporting that a woman dropped a bag of $120,000 in cash at her home and offered her more money if she would vote to acquit seven people ⁠charged with stealing⁠ more than $40 million. Also, Brought to you by: Lasara.com/HardFactor - Get 10% off getting in the best shape of your life at  Lasara Men's Health Patreon.com/HardFactor - Support the pod and get access to Discord Chat with the Hosts, and up to 3 Weekly Bonus Podcasts! (00:00:00 - 00:01:38) Teasers!

Virginia Public Radio
Company that bred beagles for research pleads guilty to neglect, ordered to pay record $35M fine

Virginia Public Radio

Play Episode Listen Later Jun 3, 2024


Two years ago, police and federal agents raided a dog-breeding facility west of Richmond, confiscating more than 4,400 animals – many in urgent need of veterinary care. Sandy Hausman reports that Envigo pleaded guilty Monday to a violation of the Animal Welfare Act and will pay the largest fine in history for that offense.

THE PETA PODCAST
Ep. 315: Bainbridge, Georgia Residents Fight Monkey Farm With Assist From PETA

THE PETA PODCAST

Play Episode Listen Later Feb 14, 2024 27:50


A new company formed by former key employees of Charles River Labs and Envigo is trying to build a monkey farm in Bainbridge, Decatur County,  Georgia that will house up to 30,000 monkeys to be bred for experimentation. But they never told the residents about the plans. Now PETA is helping them put a stop to the project. Amy Meyer, PETA's manager of primate experimentation, talks to Emil Guillermo. Take action here. The PETA Podcast PETA, the world's largest animal rights organization, is 9 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Hosted by Emil Guillermo. Powered by PETA activism. Contact us at PETA.org. Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Get the podcast on YouTube.  www.YouTube.com/@emilamok1 Please subscribe, rate, and review wherever you get your podcasts.  Thanks for listening to THE PETA PODCAST! Originally released Feb.13, 2024. ©PETA, Emil Guillermo 2024

Chicago's Afternoon News with Steve Bertrand
Anderson Humane finds forever homes for beagles rescued from VA Envigo Facility

Chicago's Afternoon News with Steve Bertrand

Play Episode Listen Later Aug 22, 2023


Dean Daubert, chief operations officer at Anderson Humane in South Elgin, joins Lisa Dent to talk about how they rescued 200 beagles from Virginia’s Envigo Medical Facility and found forever homes for them in Illinois. Follow The Lisa Dent Show on Twitter:Follow @LisaDentSpeaksFollow @SteveBertrand Follow @kpowell720 Follow @maryvandeveldeFollow @LaurenLapka

Plant Based Briefing
525: A Vegan Behind the Scenes of the Envigo Beagle Rescue by Karen Asp at MainStreetVegan.com

Plant Based Briefing

Play Episode Listen Later Apr 28, 2023 9:07


A Vegan Behind the Scenes of the Envigo Beagle Rescue by Karen Asp at MainStreetVegan.com   Original post: https://mainstreetvegan.com/a-vegan-behind-the-scenes-of-the-envigo-beagle-rescue-by-karen-asp-ma-cpt-vlce/  Related Episodes:  273: [Part 1] Why Aren't More Veterinarians Vegan? 274: [Part 2] Why Aren't More Veterinarians Vegan?    Main Street Vegan Academy is the premier training & certification program for Vegan coaches. Their mission is to encourage the adoption and maintenance of a positive vegan lifestyle and a health-promoting diet, geared to the needs and preferences of the individual, for the purpose of creating a just world for all beings and protecting this planet. Founder Victoria Moran went vegan in 1983; overcame a binge-eating disorder; in 1985 wrote Compassion the Ultimate Ethic, the first book about Vegan philosophy and practice to come from an actual publisher; raised a Vegan daughter; wrote 12 additional books and has another on the way; and appeared twice on Oprah. Learn more at https://MainStreetVegan.com   How to support the podcast: Share with others. Recommend the podcast on your social media. Follow/subscribe to the show wherever you listen. Buy some vegan/plant based merch: https://www.plantbasedbriefing.com/shop    Follow Plant Based Briefing on social media: Twitter: @PlantBasedBrief YouTube: YouTube.com/PlantBasedBriefing  Facebook: Facebook.com/PlantBasedBriefing  LinkedIn: Plant Based Briefing Podcast Instagram: @PlantBasedBriefing   #vegan #plantbased #plantbasedbriefing #veganeducation #envigo #beaglerescue #animalrescue #beagles #animaltesting #dogbreeding    

Species Unite
Eric Kleiman: Trafficked Monkeys, the Envigo Beagles and the Many Abject Failures of the USDA

Species Unite

Play Episode Listen Later Feb 8, 2023 38:07


“There is this long history, and what's important about history is history informs the present. History shows this is how we got here. Fred Colston was like a villain out of central casting. I mean… it's almost like he was twirling his mustache… And he blamed me. He blamed me for bankrupting his lab. I mean, that's in documents from the federal government, not me by name, but In Defense of Animals. The thing is, at least he was honest about his viewpoints. At least he was honest to say, ‘these chimpanzees, I want to raise them like cattle.' Whereas today you've got these slick PR people like Inotiv or Envigo, ‘Oh, animal welfare is our highest priority.' It's the same mindset. At least he was honest about it. They're not honest anymore.” – Eric Kleiman   You've probably heard of Envigo. They were the ones who owned the 4000 beagles that were rescued in Virginia last summer. The Beagles were living at a breeding facility, a breeding facility for research animals, and their conditions were so abusive and horrific that they got rescued. That doesn't happen very often. It was a big deal.   And more recently, federal prosecutors charged eight members of an international monkey smuggling ring that allegedly supplied trafficked and endangered monkeys to Envigo, Orient and Worldwide Primates.    The USDA are the people who are supposed to be at least somewhat on the side of animals in all of this. They are supposed to be doing inspections and shutting places like these down. But they're not. They're not the people who shut down Envigo and rescued all those dogs, because they're not doing their job. They've rarely done their job. And this job needs to go to someone else because animals need someone who's actually on their team.   Today's episode is about the people who are doing the work.   This conversation is with Eric Kleinman. Eric is a researcher at the Animal Welfare Institute and he knows more about this stuff than I think anyone. I'm going to warn you in advance, it's complicated and there are a lot of acronyms (one that you need to know is APHIS – Animal and Plant Health Inspection Services, a part of the USDA). It's also extremely important.   Links:  AWI: https://awionline.org/   To learn more: https://www.nationalgeographic.co.uk/animals/2022/06/what-do-we-owe-former-lab-chimps https://www.nationalgeographic.com/animals/article/toothless-and-paltry-critics-slam-usda-fines-for-animal-welfare-violations https://www.science.org/content/article/indictment-monkey-importers-could-disrupt-u-s-drug-and-vaccine-research https://www.nationalgeographic.com/animals/article/what-do-we-owe-former-lab-chimps https://www.science.org/content/article/research-animals-mistreated-leading-supplier-animal-welfare-group-alleges https://www.science.org/content/article/leading-breeder-beagles-research-slammed-animal-welfare-inspectors https://www.science.org/content/article/beleaguered-beagle-facility-closes-under-government-pressure-fate-3000-dogs-unclear https://www.nationalgeographic.com/animals/article/hundreds-of-beagles-have-died-at-a-major-research-animal-breeding-facility https://www.nationalgeographic.com/animals/article/usda-accused-of-ignoring-animal-welfare-for-business-interests

THE PETA PODCAST
E.259: PETA Victories: Ending Experiments, Saving Animals

THE PETA PODCAST

Play Episode Listen Later Jan 18, 2023 28:29


Kathy Guillermo talks about some of PETA's big victories in 2022, starting with FDA Modernization Act, and what it means for you and the animals. She also talks about the victories for dogs at Envigo in Virginia, and at Texas A&M. See more on the FDA Modernization Act at PETA.org. See more on the Texas A&M dogs. See PETA's top victories for 2022.   The PETA Podcast PETA, the world's largest animal rights organization, is 6.5 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Contact us at PETA.org Listen to the very first PETA podcast with Ingrid Newkirk Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Please subscribe, rate and review wherever you get your podcasts. Thanks for listening to THE PETA PODCAST! released Jan. 18, 2023 copyright @PETA, all rights reserved.

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The Daily Dive
Xi Claims a Third Term in China and the Rescue of the Envigo Beagles

The Daily Dive

Play Episode Listen Later Oct 24, 2022 20:00


Xi Jinping has claimed a third term as the Communist Party leader in China.  He will now serve another five-year term overseeing the world's second largest economy and a growing military continuing to pose threats to the U.S. on multiple fronts.  Julia Manchester, national political reporter at The Hill, joins us for the latest in China and more.  With the midterm elections just a few weeks away, Democrats are getting more worried about their prospects, and we'll get a preview of the high-stakes Pennsylvania Senate debate on Tuesday.   Next, it was the largest animal welfare seizure in the Humane Society's history.  Nearly 4,000 beagles were rescued from the Envigo facility in Virginia where they were breeding dogs for research.  After USDA investigators found horrible conditions there, an undercover investigation by PETA, and a lawsuit filed by the Justice Department, a judge ruled that the dogs be surrendered to the Humane Society.  But that was only the beginning, then came the huge task of retrieving and adopting out the dogs, some of which had health and behavioral problems.  Lizzie Johnson, staff writer at the Washington Post, joins us for the rescue of the Envio beagles.See omnystudio.com/listener for privacy information.

Dog Talk ® (and Kitties Too!)
What it was like in “the Devil’s Den” — Envigo Beagle Breeding facility

Dog Talk ® (and Kitties Too!)

Play Episode Listen Later Sep 12, 2022


State Senator Bill Stanley on putting a stop to --- and driving Envigo beagle breeding/experimentation facility out of Virginia

One Life Radio Podcast
Ingrid Newkirk - PETA Update, McCall Knecht - How Safe is Our Tap Water?

One Life Radio Podcast

Play Episode Listen Later Sep 9, 2022


It's Furry, Furbulous Friday! Ingrid Newkirk, President of PETA, (the People for the Ethical Treatment of Animals), joins us to fill us in on all the great work they do to save animals. We also touch on the work of Queen Elizabeth II who passed away yesterday. She and Bern also discuss the recent rescue of 4,000 beagles from the Envigo lab, PETA's amazing dog house project, and much more. Learn how you can help support PETA's efforts at peta.org.Next, we're excited to talk with McCall Knecht of Berkey Filters, a sponsor of One Life Radio, regarding the safety of our drinking water. Most of us have heard of the conditions in Mississippi after a flood. They had no drinking water, or even water to flush their toilets. What would you do in that situation? A Berkey Filter doesn't need electricity, and can easily be used to provide clean drinking water during a power outage or mechanical failure at your city water plant. It's also a must if you want healthy, clean drinking water every day. Find out what's in your water supply with Berkey Filter's Water Quality Search (created in partnership with the Environmental Working Group, or EWG). Don't drink what the EWG refers to as a “chemical cocktail” every time you drink from the tap. Visit Berkey Filter to check out their line of water filters. They even have a travel size for camping. And, for a limited time, use the code OLR for 10% off your purchase! Thank you to our sponsors!enviromedica – The BEST probiotics on the planetWise Traditions Conference - October 21st - 23rd in Knoxville, TNIs your drinking water safe? Check by zip code at berkeyfilters.com and use the code OLR for 10% off a new Berkey Water Filter!Children's Health Defense - Order Robert F. Kennedy's latest book, "The Real Anthony Fauci" today!sunwarrior - Use the code OLR for 20% off your purchase!Vegworld MagazineWell Being JournalThorne - Get 20% off your order and free shipping!

Catch The Sky Podcast
Episode 120 - Tin Foil Hats Vol. V: Envigo Beagles

Catch The Sky Podcast

Play Episode Listen Later Sep 2, 2022 8:11


Dick Francisco is not on siesta this week, but T was so busy saving the world one-dog-at-a-time that he had to do this one solo. This episode is dedicated to his new Beagle, Pam, and looks into the terrible situation she was saved from as part of the Envigo scandal. Thank you for tuning in and giving us your continued support. Please follow Catch The Sky Podcast on Facebook, Instagram, YouTube, or @CTSTerry on Twitter to keep interact with us on social media or subscribe wherever you listen to podcasts. Music by Emby Alexander Shout-out to the A.N.N.A. Shelter for connecting T with this angel Recorded September 2, 2022 #CatchTheSky #Podcast #DickFrancisco #Dog #Puppy #Beagle #Envigo #Pam #TheOffice #Conspiracy #Adopt #Shelter #ANNA #Frank #Research #BigPharma #Breeding #AlwaysBeComing #TrashRocket #EmbyAlexander

Leaning Right and Turning Left with Sadler and the Senator
Saving The Envigo Beagles With Kindness Ranch's John Ramer

Leaning Right and Turning Left with Sadler and the Senator

Play Episode Listen Later Sep 1, 2022 138:31


This episode provides a behind the scenes look of all the work that has gone into rescuing the Envigo Beagles from a painful life of needless scientific experimentation at the Cumberland Breeding Facility in Virginia, with one of the original “beagle warriors,” John Ramer of Wyoming's Kindness Ranch. Along with Homeward Trail's Sue Bell, Senator Stanley and Hermie, John Ramer did not hesitate to jump into action to save these precious pups. Hear how it all happened from the very beginning, and how the ongoing removal of over 4,000 beagles from the Cumberland facility is progressing. And, hear the wonderful story about Uno, Ramer's beagle that was the first to be loaded on the Kindness Ranch van, and who immediately touched the Ramer family's heart. In Senator Stanley's Leaning Right Moment, Hermie and Bill discuss the unfairness of Biden's student loan bail out for the liberal educational elites, whether Republicans are “semi-facists” as the President claims, and Virginia's Governor's push back on 2021 legislation signed by his predecessor Ralph Northam that will tie Virginia's greenhouse gas emissions to the ridiculous standards of California. Hermie uses his Turning Left Moment to discuss the resumption of the SMART Series at Carteret, and makes a special announcement about the SMART race at Orange County that you won't want to miss. The Leaning Right and Turning Left With Sadler and The Senator is proudly sponsored by Pace-O-Matic, an entertainment company which develops gaming software that players love to play and can use their skills to win, every time. Pace-O-Matic is focused on people having fun, the small businesses that love them, and generates millions of dollars in Virginia. Their skill games are played in restaurants, bars and convenience stores all across Virginia, and the revenues from these games help these family-owned businesses thrive.   Pace-O-Matic develops, produces, and licenses legally compliant games in every state where we operate. Since POM was founded in 2000, we have built a talented leadership team and a company culture defined by integrity, innovation, and compliance. Visit https://www.paceomatic.com for more information. Learn more about your ad choices. Visit megaphone.fm/adchoices

Richmond's Morning News
Tabitha Treloar: August 30, 2022

Richmond's Morning News

Play Episode Listen Later Aug 30, 2022 8:50


Director of Communications for the Richmond SPCA Tabitha Treloar provides an update on how to adopt the beagles from the Envigo puppy mill.

Good Mornings Podcast Edition
Thursday, August 25, 2022

Good Mornings Podcast Edition

Play Episode Listen Later Aug 25, 2022 58:05


Last month's rescue of thousands of dogs from a Virginia research breeding facility made big headlines... we speak to one of the individuals who spearheaded the investigation into the inhumane practices at Envigo (at 15:13) --- The Flag City Morning Rotary is seeking grant applications from non-profits in Hancock County (at 24:09) --- Community and Business Spotlight: How much do you know about addiction, overdose and its true impact on our community? Hancock Public Health is hosting an awareness event this week (at 33:04) --- For National Aviation Week, we salute military pilots and support staff and highlight career opportunities in this field within the US Army Reserve (at 51:13)

Leaning Right and Turning Left with Sadler and the Senator
Envigo Beagles Freed, and Double J and Ric Flair Do The Wrasslin' Deed!

Leaning Right and Turning Left with Sadler and the Senator

Play Episode Listen Later Aug 18, 2022 148:39


In this week's explosive episode, Sadler and The Senator pull off an action packed double header with two powerful guests! First, Homeward Trails Hero Sue Bell and the boys discuss the previously untold behind the scenes story of the rescue of over 4000 beagles from the Envigo plant in Virginia, saving these beautiful furry souls from a life of painful scientific experimentation, and giving them a chance at life and to be loved in a furrever home. Next, Hermie and Bill talk with their Podcast Heat Boss, WWE Hall of Famer “Double J” Jeff Jarrett, about his new job with the WWE (now that Vince McMahon has retired), and his epic final match with The Nature Boy, Ric Flair! In Sadler's Turning Left Moment, Hermie discusses the recent wins by Kevin Harvick at both Michigan and Richmond, the upcoming NASCAR® Playoffs, and even talk about where some of this year's drivers may end up with different rides next year. In the Senator's Leaning Right Moment, The Senator and Sadler discuss the current issues in public education in Virginia, whether a teacher should keep secrets about their students from their parents, and once again debunk the “Big Fib” made by the Virginia Lottery (and some state legislators) that legal skill games harm Virginia Lottery sales and revenues (Major hint: they don't).  As always, The Leaning Right and Turning Left With Sadler and The Senator is sponsored by Pace-O-Matic, an entertainment company which develops gaming software that players love to play and can use their skills to win, every time. Pace-O-Matic is focused on people having fun, the small businesses that love them, and generates millions of dollars in Virginia. Their skill games are played in restaurants, bars and convenience stores all across Virginia, and the revenues from these games help these family-owned businesses thrive.  Learn more about your ad choices. Visit megaphone.fm/adchoices

News in Simple Turkish/Basit Türkçe ile Haberler

Basit Türkçe ile Haberler / News in Simple Turkish by skypeturkish.com Basit Türkçe ile Haberler'in yeni bölümüne hoş geldiniz. Bugün 10 Ağustos 2022 Çarşamba. ABD'de 4 Bin Beagle'a Yuva Aranıyor Amerika Birleşik Devletleri'nin Virginia eyaletinde bir tesis, beagle cinsi köpekler yetiştiriyordu. Tesis, bu köpekleri ilaç deneyleri için laboratuvarlara satıyordu. ABD Adalet Bakanlığı, tesisin sahibi Envigo şirketine mayısta dava açtı. Çünkü bu tesis, hayvanlara kötü davranıyordu. Bazı köpekler açtı. Bazıları sağlıksız mama yiyordu. Bazıları soğuktan ölüyordu. Yetkililer geçen hafta tesisi kapattı. Bölgedeki yardım kuruluşları köpekleri sahiplendirmeye çalışıyor. Yaklaşık 4 bin köpeğe yeni yuva aranıyor. Köpeklere bugünlerde sağlık kontrolü ve aşı yapılıyor. Yardım kuruluşlarına göre, bazı köpeklerde travma belirtileri var. Örneğin, bazı yavrular oyun oynamayı bilmiyor. Hayvan hakları kuruluşu Humane Society'nin Başkanı Kitty Block, "Bütün köpekleri tesisten çıkarmamız en az 60 gün sürecek. Onları, sevgi görecekleri evlere vermek istiyoruz" dedi. Dinlediğiniz için teşekkürler! Lütfen bu bölümü Türkçe öğrenen diğer kişilerle de paylaşın! Yeni bölümde görüşmek dileğiyle, hoşça kalın!

THE PETA PODCAST
Ep. 235: How 4,000 Beagles Were Saved from Animal Testing

THE PETA PODCAST

Play Episode Listen Later Aug 3, 2022 41:26


The real story behind the freeing of 4,000 beagles from animal testing supplier Envigo. All it took was one PETA undercover investigator to provide the evidence that allowed for the dogs to be set free. Dan Paden, PETA VP of Evidence Analysis talks to Emil Guillermo about how the case evolved from the state to the federal level, ultimately freeing the dogs and shutting down Envigo. Paden also talks about how you can adopt a dog. He also outlines how the Envigo dogs are just a fraction of all the animals subject to animal testing.  Paden says they all can be saved if PETA's idea of the  Research Modernization Act is passed. Go to PETA.org for more.   The PETA Podcast PETA, the world's largest animal rights organization, is 6.5 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Hosted by Emil Guillermo. Powered by PETA activism. Contact us at PETA.org Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Please subscribe, rate and review wherever you get your podcasts. Thanks for listening to THE PETA PODCAST!   © Copyright PETA 2021-4  

One Life Radio Podcast
Kirsten Peek - Humane Society of the US 4,000 Beagles Rescued

One Life Radio Podcast

Play Episode Listen Later Jul 29, 2022


Happy Furry Friday everyone! We have Kirsten Peek from the Humane Society of the United States joining us today to tell us all about their biggest rescue in history currently underway in Virginia. Approximately 4,000 beagles are being transported from a mass breeding facility, Envigo, who bred the dogs specifically for use in laboratory experiments. It was a long battle, but now these dogs have a furever home in their future! Kirsten Peek is the public information office for the Humane Society of the United States' animal rescue team. She deploys with the rescue team during large-scale cruelty cases and disasters. Kirsten previously worked as a journalist, and now lives in Washington DC with her dog, Flea, and several foster animals. To find out where the beagles will be heading to adopt or foster, visit humanesociety.org.Thank you to our sponsors!enviromedicaThe Weston A. Price FoundationChildren's Health Defense - Order Robert F. Kennedy's latest book, "The Real Anthony Fauci" today!sunwarrior - Use the code OLR for 20% off your purchase!Ice Shaker - Keeps drinks ice cold all day!Vegworld MagazineWell Being JournalThorne - Get 20% off your order and free shipping!

O'Connor & Company
07.25.22: [Hour 3 / 7 AM]: Joe diGenova, Critter News, Dave Kallman, DNA Testing Warning

O'Connor & Company

Play Episode Listen Later Jul 25, 2022 27:55


In the third hour of the morning show, Larry O'Connor and Julie Gunlock talked to legal analyst Joe diGenova and Dave Kallman.  They also discussed: This person uses frogself/bug pronouns and we are expected to remember and affirm frog https://twitter.com/heatherhunterdc/status/1551342067531620352 Giant Panda Mei Xiang enjoys ice cake at National Zoo to celebrate turning 24! https://wjla.com/news/local/giant-panda-mei-xiang-eating-ice-cake-turning-24-birthday-smithsonian-national-zoo-stay-cool-heat-wave-washington-dc-frozen-treats-dmv-giant-panda-cam ‘Spa day' in Arlington for beagles rescued from Envigo https://wtop.com/gallery/virginia/photos-spa-day-in-arlington-for-beagles-rescued-from-envigo/ Raging rat brutally attacks pigeon in NYC showdown https://twitter.com/BoSnerdley/status/1550772558328471553 Intelligence Committee members warn US of bioweapons targeting DNA of individual  https://www.foxnews.com/us/intelligence-committee-members-warn-bioweapons-targeting-dna-individual-americans For more coverage on the issues that matter to you, visit www.WMAL.com, download the WMAL app or tune in live on WMAL-FM 105.9 FM from 5-9 AM ET. To join the conversation, check us out on Twitter: @WMALDC, @LarryOConnor, @Jgunlock,and @patrickpinkfile. See omnystudio.com/listener for privacy information.

WMRA Daily
WMRA Daily 6/20/22

WMRA Daily

Play Episode Listen Later Jun 20, 2022 7:48


A judge orders the dog-breeding facility shut down in May to cease breeding new puppies, and the Envigo operation will shut down permanently… The General Assembly rejects the governor's amendments on abortion and a gas tax holiday, but his effort to redirect money to HBCU's went through… Lawmakers also filled two vacancies on the state Supreme Court, and we have a review of Friday's activity….

THE PETA PODCAST
Ep.228: Stopping Envigo, Saving Beagles

THE PETA PODCAST

Play Episode Listen Later Jun 15, 2022 26:32


The fate of 3,000 beagles bred for experimentation is in doubt as this podcast reaches the public. Envigo, a multi-million dollar supplier of dogs for lab experimentation worldwide, is accused of violations under the Animal Welfare Act after a PETA undercover investigation exposed horrible conditions at Envigo's Virginia facility. The Department of Justice has sought to close down the facility. But Envigo wants to sell off its remaining 3,000 dogs to labs for experimentation first. Daphna Nachminovich, PETA Sr. VP for Animal Cruelty explains why that's unacceptable. She wants animal lovers to join PETA in forcing Envigo to give up all the dogs to safe and caring homes. See how you can save the beagles. Go to PETA.org. Find out more at PETA.org. The PETA Podcast PETA, the world's largest animal rights organization, is 6.5 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Hosted by Emil Guillermo. Powered by PETA activism. Contact us at PETA.org Listen to the very first PETA podcast with Ingrid Newkirk Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Please subscribe, rate and review wherever you get your podcasts. Help us grow the podcast by taking this short survey. Thanks for listening to THE PETA PODCAST! Originally released June 15, 2022. copyright 2022-3

apple saving stopping powered animal cruelty beagles animal welfare act envigo emil guillermo peta podcast
VPM Daily Newscast
06/06/22 - Cumberland beagle breeders shut down by Feds as Virginia toughens laws

VPM Daily Newscast

Play Episode Listen Later Jun 6, 2022 6:12


A federal judge issued a restraining order last month against the dog breeding facility Envigo in Cumberland County for repeated violations of the Animal Welfare Act, and the deaths of hundreds of beagle puppies.

THE PETA PODCAST
Ep. 220: PETA Investigation Nets Five New Laws to Protect Animals Bred for Experimentation

THE PETA PODCAST

Play Episode Listen Later Apr 20, 2022 40:58


It's no small thing to bring together a divided government in Virginia and get them to unanimously pass five new laws to save dogs bred for experimentation. But that's what happened after a PETA undercover investigation exposed cruelty at Envigo in Virginia, a 5,000 dog breeding farm that was more like a prison. PETA documented deplorable conditions at Envigo including finding more than 360 dead dogs on the premises. But when the feds wouldn't take action, PETA went to Virginia's state legislators. Normally gridlocked and divided, the legislature, at PETA's urging, came together to fight animal cruelty. PETA Sr. VP Daphna Nachminovich talks to Emil Guillermo about how the investigation sparked passage of new laws holding Envigo accountable. Go to PETA.org to learn more: The Envigo Investigation How the U.S. Senate is taking action. The PETA Podcast PETA, the world's largest animal rights organization, is 6.5 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Hosted by Emil Guillermo. Powered by PETA activism. Contact us at PETA.org Listen to the very first PETA podcast with Ingrid Newkirk Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Please subscribe, rate and review wherever you get your podcasts. Help us grow the podcast by taking this short survey. Thanks for listening to THE PETA PODCAST! (Originally released  April 19, 2022).

THE PETA PODCAST
Ep. 204: The Animals' "Vivisection Hell"

THE PETA PODCAST

Play Episode Listen Later Dec 29, 2021 49:03


Following a PETA undercover investigation, the Washington Post further exposed animal mistreatment at the Envigo dog breeding facility. The USDA has cited Envigo with multiple violations. And where do the dogs of Envigo end up? The journey is only beginning as the dogs are sold to researchers and scientists, many of whom are funded by NIH. They will use the animals in cruel, non-productive research, discarding the animals when they are no longer useful. Jeremy Beckham talks to Emil Guillermo about the vivisection hell that the animals are subjected to. Go to PETA.org for more. PETA's Investigation. The PETA Podcast PETA, the world's largest animal rights organization, is 6.5 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Hosted by Emil Guillermo. Powered by PETA activism. Contact us at PETA.org Listen to the very first PETA podcast with Ingrid Newkirk Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Please subscribe, rate and review wherever you get your podcasts. Thanks for listening to THE PETA PODCAST! (Vivisection Hell originally published in 2018;  reprised, Dec.29,  2021). Copyright 2021 For more go to PETA.org

THE PETA PODCAST
Ep. 201: PETA Undercover Reveals Envigo Hell for Beagles

THE PETA PODCAST

Play Episode Listen Later Dec 8, 2021 34:11


A PETA undercover investigator has uncovered a factory farm-like facility whose intent is to raise animals for food. But in Virginia, the intent is to breed hundreds upon hundreds of dogs for sale to animal experimenters. Dan Paden, VP of accident analysis, talks to Emil Guillermo. Take action now! Go to PETA.org. Listen to PETA PODCAST on Research Modernization Deal. The PETA Podcast PETA, the world's largest animal rights organization, is 6.5 million strong and growing. This is the place to find out why. Hear from insiders, thought leaders, activists, investigators, politicians, and others why animals need more than kindness—they have the right not to be abused or exploited in any way. Hosted by Emil Guillermo. Powered by PETA activism. Contact us at PETA.org Listen to the very first PETA podcast with Ingrid Newkirk Music provided by CarbonWorks. Go to Apple podcasts and subscribe. Contact and follow host Emil Guillermo on Twitter @emilamok Or at www.amok.com Please subscribe, rate and review wherever you get your podcasts. Thanks for listening to THE PETA PODCAST! (Originally published  Dec. 8, 2021). Copyright 2021

PaperPlayer biorxiv neuroscience
Transcriptomic signatures of sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Oct 6, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.05.327155v1?rss=1 Authors: Kozlova, A., Butler, R. R., Zhang, S., Ujas, T., Zhang, H., Steidl, S., Sanders, A. R., Pang, Z. P., Vezina, P., Duan, J. Abstract: Rodents are frequently used to model drug addiction, yet their genetic relevance to human addictive behaviors especially the mounting genome-wide association study (GWAS) findings is poorly understood. Considering a possible gateway drug role of nicotine (NIC), we modeled NIC addiction, specifically NIC sensitization (SST) and self-administration (SA), in F1 progeny of inbred Envigo rats (F344/BN) and conducted integrative genomics analyses. We unexpectedly observed male-specific NIC SST and a parental effect of SA only present in paternal F344 crosses. Transcriptional profiling in the ventral tegmental area (VTA) and nucleus accumbens (NAc) core and shell further revealed sex and brain region-specific transcriptomic signatures of SST and SA. We found that genes associated with SST and SA were enriched for those related to synaptic processes, myelin sheath, and tobacco use disorder or chemdependency. Interestingly, SST-associated genes were often downregulated in male VTA but upregulated in female VTA, and strongly enriched for smoking GWAS risk variants, possibly explaining the male-specific SST. For SA, we found widespread region-specific allelic imbalance of expression (AIE), of which genes showing AIE bias towards paternal F344 alleles in NAc core were strongly enriched for SA-associated genes and for GWAS risk variants of smoking initiation, likely contributing to the parental effect of SA. The transcriptional signatures of sex-specific nicotine SST and SA suggest a mechanistic link between genes underlying these processes and human nicotine addiction, providing a resource for understanding the biology underlying the GWAS findings on human smoking and other addictive phenotypes. Copy rights belong to original authors. Visit the link for more info

PaperPlayer biorxiv neuroscience
Sex difference in the modulation of responding to an alcohol-predictive cue by an alcohol-associated context

PaperPlayer biorxiv neuroscience

Play Episode Listen Later Sep 10, 2020


Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.10.292201v1?rss=1 Authors: Segal, D., Valyear, M. D., Chaudhri, N. Abstract: The rats used in the current study were bred in our on-site TH::Cre rat breeding colony, in which 4 heterozygote TH::Cre positive dams were paired with 2 wild type sires (Charles River, St. Hubert, QC). Pups were weaned at twenty-three days post-natal, seprated by sex, and pair-housed in polycarbonate shoebox cages containing beta chip bedding (Aspen Sani chips; Envigo, Indianapolis, IN), a nylabone chew toy (Nylabones, Bio-Serv, Flemington, NJ), a red plastic tunnel (Rat retreats, Bio-Serv, Flemington, NJ), and shredded paper for enrichment, with unrestricted access to standard rat chow (Rodent Diet, Charles River, St. Hubert, QC) and water. Males and females were housed on separate walls within the breeding colony room held at 21 +/- 2 degrees celsius and approximately 40-50% humidity on a 12-hour light-dark cycle (lights on at 0700 hours). One week following weaning, two rounds of pinna samples were collected, and two rounds of genotyping were conducted to verify the genotype of each rat. Those that showed a negative genotype in both rounds (n = 31) were selected for the current study. Rats were transferred into the colony room at ~9 weeks of age and single housed (See Methods). Copy rights belong to original authors. Visit the link for more info