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Op donderdag 1 mei was het precies tien jaar geleden dat New Business Radio feestelijk van start ging. New Business Radio schreef hiermee direct radiohistorie, want het station was hiermee het eerste Nederlandse radiostation volledig gericht op ondernemerschap, met innovatie en duurzaamheid als belangrijkste pijlers. Gelegenheidsredactie Het eerste programma op de nieuwe zakenzender werd destijds gemaakt door een gelegenheidsredactie, bestaande uit MVO manager van het jaar Annette van Waning, oud-hockeyinternational Jacques Brinkman en singer-songwriter Leonie Meijer. Met slechts een paar uur voorbereiding, zonder radio ervaring en zonder draaiboek verzorgde dit team de redactie, presentatie en de interviews van de live openingsuitzending met eerste studiogast Alexander Pechtold. Duurzame economie Alexander Pechtold liet tijdens de openingsuitzending weten: “Ik ben met plezier te gast in de eerste uitzending van dit vernieuwende radiostation, omdat dé thema's van de nabije en verre toekomst centraal staan. Nederland kennisland is ondanks z'n beperkte omvang altijd een belangrijke speler in de wereldeconomie. Ondernemerschap en onze innovatieve kracht zijn belangrijke pijlers onder die sterke positie. Maar als er één terrein is waarop Nederland nog kansen laat liggen, dan is het de transitie naar een duurzame economie. Terwijl duurzaamheid al lang geen geitenwollensokken thema meer is. Het ademt innovatie, het is de basis onder nieuwe economische groei en het betekent vooral ook werk. Werk en kansen voor innovatieve bedrijven. Zie hoe DSM van een kolenbedrijf uitgroeide tot een innovatietopper. De overheid moet daarom het bedrijfsleven zekerheid bieden met harde afspraken en harde doelen.” Speciale uitzending Donderdag 1 mei blikten Ron Lemmens en Glenn van der Burg, in een speciale uitzending op New Business Radio, terug op de feestelijke openingsuitzending van 1 mei 2015.
MVO Uncensored Rundown It's been a year since the last episode of MVO. Let's run through what has transpired since then. Diddy is locked up. Is it really over?Drake vs. Kendrick Them folks tried to get Hov50 Cent started beefing with Big MeechYoung Thug beat the RICO charges Yella Beezy arrested for Mo3 murder, shooter to testify against himLil' Wayne didn't play the Super BowlASAP Rocky beat the case Kanye loves Hitler and the KKKIs rap for the bitches now?Max B getting out again in November Best albums of the last year?Who won 2024?Who is the biggest hip hop figure to pass away in the last year?What's on your playlists in 2025?
Steeds meer mensen voelen zich niet langer thuis in Nederland. Sommigen worden financieel leeggezogen door de Belastingdienst
Waardeer je onze video's? Steun dan Café Weltschmerz, het podium voor het vrije woord: https://www.cafeweltschmerz.nl/doneren/In deze aflevering spreken we met Pim van Rijswijk over ondernemerschap in Nederland en de obstakels waar ondernemers vandaag de dag tegenaan lopen. Daarnaast bespreken we zijn MVO Masterclass op 11 april, een uniek event voor ondernemers die toekomstgericht willen groeien.Exclusieve actie voor onze kijkers: De eerste 20 personen kunnen met 50% korting een ticket bemachtigen met de code MVO-cafeweltschmerz Wees er snel bij! https://shop.ikbenaanwezig.nl/tickets/event/masterclass-voor-ondernemers-2025 ---Deze video is geproduceerd door Café Weltschmerz. Café Weltschmerz gelooft in de kracht van het gesprek en zendt interviews uit over actuele maatschappelijke thema's. Wij bieden een hoogwaardig alternatief voor de mainstream media. Café Weltschmerz is onafhankelijk en niet verbonden aan politieke, religieuze of commerciële partijen.Wil je meer video's bekijken en op de hoogte blijven via onze nieuwsbrief? Ga dan naar: https://www.cafeweltschmerz.nl/videos/Wil je op de hoogte worden gebracht van onze nieuwe video's? Klik dan op deze link: https://bit.ly/3XweTO0
MVO and Ezra are joined by a panel of guests to discuss the results of the Gervonta 'Tank" Davis vs 'The Ghost" Frank Martin Pay Per View event.
In special edition of Brunch Boxing, MVO is joined by Hall of Famer, and legendary boxing commentator Al Bernstein for conversation about his beginning in boxing, and as a singer, some of his favorite fights to call, and the best fighters in boxing today,
MVO and EzRAW speak with long time combat sports journalist John S. Nash to discuss the current state of the business of boxing including the recent Riyadh Season expansion, and what it could mean for the sport. Hey Not The Face! SubStack (Podcast)Brunch BoxingSaturday:Brunch Boxing Full Tank vs Frank Preview @ 11AM EST Twitter Spaces & Spotify
MVO sits down for a conversation with boxing journalist Paul Magno about his history in the sport, and the current events in boxing.
Ez RAW and MVO discuss the rumor of a Boxing League being formed by Turki Alalshikh and how this would effect boxing as a whole.
Brunch Boxing has a special mid-week episode for MVO, and EzRAW to discuss the grand arrivals for Gervonta "Tank" Davis vs "The Ghost" Frank Martin, the upcoming cards, and other recent boxing events.Brunch Boxing Fight Week Schedule: Wednesday: Brunch Boxing Final Presser Special Edition @ 6PM EST Twitter Spaces & Spotify Brunch Boxing on Women Crushing It Wednesdays @ 9PM EST InRingWithChristine YouTube Thursday: Brunch Boxing 50 Greatest African American Boxers of All Time List @ 8PM EST Twitter Spaces, Spotify, YouTube & http://BrunchBoxing.com Friday: Brunch Boxing on The Ringer Gambling Show @11AM EST Spotify Brunch Boxing Special Weigh In Edition @ 7:30PM EST Twitter Spaces & Spotify Saturday: Brunch Boxing Full Tank vs Frank Preview @ 11AM EST Twitter Spaces & Spotify
In this mid-week edition, MVO presents Brunch Boxing's list of the 50 Greatest African American Boxers of All Time. Afterwards, he's joined by JBro and Cliff Rold to discuss any potential snubs, and more.Read the Article brunchboxing.comThe Corner Stool: https://roldboxing.substack.com/Brunch Boxing Fight Week Schedule:Wednesday:Brunch Boxing Final Presser Special Edition @ 6PM EST Twitter Spaces & SpotifyBrunch Boxing on Women Crushing It Wednesdays @ 9PM EST InRingWithChristine YouTubeFriday:Brunch Boxing on The Ringer Gambling Show @11AM EST SpotifyBrunch Boxing Special Weigh In Edition @ 7:30PM EST Twitter Spaces & SpotifySaturday:Brunch Boxing Full Tank vs Frank Preview @ 11AM EST Twitter Spaces & Spotify
Rashidi Ellis joins Brunch Boxing for a quick conversation with Ezra and MVO about Team Combat League, the business of boxing, and a potential matchup with Jaron "Boots" Ennis.
‘Ik ben er trots op dat ik als enige interne kandidaat in een procedure van zo'n 60 kandidaten gekozen ben' We zijn op bezoek bij de Superboeren! We zijn in Doetinchem. We zijn te gast bij Michael Ogubai. Sinds 2023 is Michael directeur betaald voetbal bij De Graafschap. Oorspronkelijk komt Michael uit Drenthe. De sfeer van De Graafschap sprak ‘m meteen aan. Mouwen opstropen en gaan. Michael stond langere tijd bekend als superboer in de Randstad toen hij daar woonde. ‘Via het netwerk kom je dan uiteindelijk toch hier in Doetinchem terecht. Ik ben hier begonnen als MVO manager, hoe kan het merk De Graafschap nog beter invulling krijgen? Ik ben er ingerold en toen kwam de directeurspositie vrij. Ik was de enige interne kandidaat. Er waren iets van 60 sollicitanten, ook ervaren bestuurders. Uiteindelijk via een assessment bleek ik de beste kandidaat. Ik ben er trots op dat ik via zo'n streng proces de beste kandidaat was'. De KNVB heeft een opleidingsprogramma voor directiefuncties in de voetbal. Er zijn coaches beschikbaar. Michael heeft de voorbije tijd gebruikt gemaakt van zo'n coach. In de podcast geeft Michael ook zijn visie op het begrip ‘businessliga'. Michael heeft sociale wetenschappen gestudeerd in Utrecht. Hij heeft altijd op het snijvlak van maatschappelijk en commercie gewerkt. Hoe ga je om met vergrijzing, hoe ga je om met gezondheid in de regio, maatschappelijke vraagstukken die ook effect hebben op onze organisatie. Michael gaat voor een duurzaam beleid met een beperkt risico. ‘Wij doen er alles aan om het talent te behouden voor de regio Achterhoek' geeft Michael aan. ‘Op dit moment hebben we veel spelers uit de eigen jeugd in het eerste elftal. Dat is natuurlijk goed voor het kapitaal wat je opbouwt'. Dat we niet zomaar bij een club zijn beland merken we als we een rondleiding in en rondom het stadion krijgen. Het is duidelijk dat deze club van en voor supporters is. We zien prachtige graffiti en supporters zijn druk met het voorbereiden van een grote sfeeractie in het stadion. Helden van weleer komen terug in verschillende vormen in en rond het stadion. Helden van vroeger worden niet vergeten. Stellingen: ➕ ‘Het hebben van een vrouwenteam, draagt bij een inclusievere voetbalorganisatie' ➕ ‘Het elftal van De Graafschap moet altijd bestaan uit spelers uit de Achterhoek' ➕ ‘Voordat ik directeur was van De Graafschap kwam ik hier ook al als supporter' ➡️
MVO, and EzRAW are joined by guests to discuss the aftermath of the Queensberry sweep of Matchroom in the 5 v 5, and what's next for the winners, and losers. Sponsors:Boxing Print Co@keepit100boxingThe Boxing SourceEvery Juan Has An Opinion (Apple Podcasts)The Corner StoolKnockouts with NaykaQueens of the Ring Boxing Talk
In this edition of Brunch Boxing, MVO, and EzRAW are joined by guest to discuss the most recent news surrounding Ryan Garcia, the Matchroom vs Queensberry 5 v 5, and other current events in boxing.Sponsors:Boxing Print Co@keepit100boxingThe Boxing SourceEvery Juan Has An Opinion (Apple Podcasts)The Corner StoolKnockouts with NaykaQueens of the Ring Boxing Talk
MVO, Ezra, and guests go through their Mid-Year Awards for 2024, Turki Alalshikh's proposed 5 v 5 card for USA vs Mexico, and more.
MVO, and Ezra are joined by guests including Claressa Shields, Franchón Crews-Dezurn, and Rachel Donaire to discuss the news of Ryan Garcia's positive B Sample. Follow Brunch Boxing on Twitter for notifications of upcoming interviews, including David Benavidez next week. Brunch Boxing: @BrunchBoxingMVO (Matt): @izdatyofaceeeEzra: @EzRawBoxing
MVO, Ezra, and guests review the top 10 southpaws of all time.
Originally published Nov 1 2021 In this episode: Kent continues his visit with Randi Mahomes, mother of Texas Tech alumnus and Super Bowl LIV-winning Kansas City Chiefs Quarterback Patrick Mahomes. Randi talks about the ups and downs of family life, why it's a good thing one of her children wasn't her firstborn, and what she misses most since Patrick achieved success. She also shares her best advice for single, working moms and lets us in on her four-year plan for Patrick as he prepared for college. Hint: It didn't work out.
‘Als we vegan op de verpakking plaatsen, schoppen we de bal te ver weg'. Aan het woord is Petra Morssinkhof, manager procesinnovatie & MVO bij Plus Retail. Ze is te gast in deze derde editie van de podcastserie Perspectief op Plantaardig waar redacteur Dionne Irving en eiwitexpert Jeroen Willemsen reflecteren op de ontwikkelingen in plantaardig.
MVO's top 10 Japanese Boxers All-Time is revealed, reviewed, and discussed.
Dure cacao, windmolenwieken en MVO managers stonden centraal in Future Friday. De cacaoprijs is door mislukte oogsten enorm gestegen. Hoe is de situatie en hoe kunnen cacaoboeren minder afhankelijk worden? Kumasi Drinks werkt met cacaoboeren samen. Waarom is de oogst mislukt en wat merken de boeren van de hogere prijs? Rogiér Power, co-founder en commercieel manager van Kumasi Drinks vertelde er meer over. Windmolens, of eigenlijk windturbines, staan bloot aan de elementen en moeten het liefst altijd draaien als wij energie nodig hebben. Ook moeten de wieken of bladen van de windturbines niet afbreken. Bij TNO hebben ze een belangrijke doorbraak ontwikkeld. Glenn ging over de ontwikkeling in gesprek met Michiel Hagenbeek, senior projectmanager bij TNO. Glenn van der Burg deelde tijdens de Future Friday Update het meest opvallende duurzaamheidsnieuws. Willemijn Simon van Leeuwen van GeoFort, Harry Boers van Macaw en Evelyn Osinga van Univé en Iris Grobben van CIRCO gaven in snelle pitches van één minuut hun brandende nieuws in Fast Forward. Voor haar boek 'Duurzaamheid is kleur bekennen' sprak Carola Wijdoogen, directeur bij stichting Sustainability University, tien duurzaamheidsmanagers die de afgelopen jaren winnaar van de 'MVO Manager van het Jaar' verkiezing zijn geworden. Welke inzichten heeft zij gekregen en welke trends ziet zij in bedrijven? Tot slot hoorde je Thijs van der Heiden van I4Nature met alles wat er buiten de studio gebeurde tijdens de uitzending. Future Friday is elke tweede vrijdag van de maand tussen 12:00 en 13:00 uur te beluisteren en te bekijken via visual radio op newbusinessradio.nl. Na de uitzending zijn alle interviews terug te luisteren via New Business Radio en alle bekende podcastkanalen. Future Friday wordt mede mogelijk gemaakt door: I4nature, Univé, Movares, Duurzaam-ondernemen.nl, het netwerk Groene Groeiers van VNO-NCW en MKB‑Nederland én Kumasi Drinks.
In deze aflevering gaat Paul Buitink in gesprek met Pim van Rijswijk en insolventie-adviseur Eric Pouw. Eric helpt met zijn kantoor ondernemers bij faillissementen en/of een doorstart van hun onderneming. Eric geeft aan dat er in 2023 60% meer faillissementen waren dan in 2022, en dat 10-15% van de ondernemers moeite heeft met betalen. Eric vertelt over zijn ervaringen in de praktijk. Met Pim van Rijswijk bespreekt Paul “MVO-2024 de springplank voor vertrek”, het evenement dat Pim organiseert op vrijdag 12 april in Ede. Pim geeft aan dat een belangrijk thema op het evenement, een eventueel vertrek uit Nederland is. En het antwoord op de vraag, hoe je je als ondernemer kunt voorbereiden op een overheid die consequent de verkeerde keuzes maakt en zorgt voor steeds meer problemen. Timestamps: 00:00 Intro 02:36 Cijfers coronaschuld 05:52 Turboliquidatie 08:45 Zombiebedrijven 12:57 Ondernemersklimaat 21:12 MVO 2024 23:54 Plan B: emigreren 33:00 Cijfers emigratie uit Nederland Overweegt u om goud en zilver aan te kopen? Dat kan via de volgende website: https://bit.ly/3xxy4sY MVO 2024 De Springplank voor Vertrek: https://www.mvo-dsvv.nl/ Kantoor Eric Pouw: https://meerjuristen.nl/wijk Twitter: @Hollandgold: / hollandgold @paulbuitink: / paulbuitink @jorisbeemsterb: / jorisbeemsterb1 @SvenKuijpers: / svenkuijpers @vrbpim: / vrbpim Let op: Holland Gold vindt het belangrijk dat iedereen vrijuit kan spreken. Wij willen u er graag op attenderen dat de uitspraken die worden gedaan door de geïnterviewde niet persé betekenen dat Holland Gold hier achter staat. Alle uitspraken zijn gedaan op persoonlijke titel door de geïnterviewde en dragen zo bij aan een breed, kleurrijk en voor de kijker interessant beeld van de onderwerpen. Zo willen en kunnen wij u een transparante bijdrage en een zo volledig mogelijk inzicht geven in de economische marktontwikkelingen. Al onze video's zijn er enkel op gericht u te informeren. De informatie en data die we presenteren kunnen verouderd zijn bij het bekijken van onze video's. Onze video's zijn geen financieel advies. U alleen kunt bepalen hoe het beste uw vermogen kunt beleggen. U draagt zelf de risico's van uw keuzes. Bekijk onze website: https://www.hollandgold.nl
MVO Uncensored Podcast Rundown: ⁃ Diddy vs Cassie: What's all the gory details? Did Diddy do it? Will Diddy ever beat the Mook allegations? Is Diddy done? ⁃ Will Smith outed by former assistant? Claims Will was getting down with Duane Martin? Will Will ever beat the Mook allegations? ⁃ Al Cood got hurt? Did stairs claim another MVO host? What happened to Al Cood? ⁃ Hassan Campbell got shot while doing a live YouTube? He'll be aight. ⁃ MVO Worldwide tryna overthrow the big fella? Al Cood sending his shooters like Jay did Kanye? Who's auditioning to be the new MVO cohost? ⁃ One gotta go: Ready to Die, Life After Death, No Way Out, Harlem World ⁃ Anything we listening to that's new? ⁃ The Big Fella reviews Power 4 Season and previews Raising Kanaan
In deze aflevering gaat Paul Buitink in gesprek met Ab Flipse en Pim van Rijswijk. Pim verwacht dat er een ongekende tsunami op ons af komt van MKB-faillissementen nu de belastingdienst alle corona schulden gaat opeisen. Verder bespreken ze de aankomende verkiezingen die Ab de belangrijkste verkiezingen ooit noemt. Pim en Ab vertellen over hun geslaagde MVO-evenement in Ede en kondigen een nieuw nog groter evenement aan in april in Ahoy. Bij de evenementen voorzien zij ondernemers van tools in deze volgens hen veeleisende tijden. Timestamps: 00:00 Intro 01:38 MVO-evenement Pim en Ab 08:15 Wakkere ondernemer 10:46 Vertrekken uit Nederland 14:55 Coronaschulden MKB 18:56 ZZP wet 25:11 Geregisseerd faillissement 35:42 Coronaclaim 42:20 Verkiezingen 53:12 Outro Overweegt u om goud en zilver aan te kopen? Dat kan via de volgende website: https://bit.ly/3xxy4sY Twitter: @Hollandgold: https://twitter.com/hollandgold @paulbuitink: https://twitter.com/paulbuitink @jorisbeemsterb: https://twitter.com/JorisBeemsterb1 @SvenKuijpers: https://twitter.com/SvenKuijpers @abflipse: https://twitter.com/abflipse Let op: Holland Gold vindt het belangrijk dat iedereen vrijuit kan spreken. Wij willen u er graag op attenderen dat de uitspraken die worden gedaan door de geïnterviewde niet persé betekenen dat Holland Gold hier achter staat. Alle uitspraken zijn gedaan op persoonlijke titel door de geïnterviewde en dragen zo bij aan een breed, kleurrijk en voor de kijker interessant beeld van de onderwerpen. Zo willen en kunnen wij u een transparante bijdrage en een zo volledig mogelijk inzicht geven in de economische marktontwikkelingen. Al onze video's zijn er enkel op gericht u te informeren. De informatie en data die we presenteren kunnen verouderd zijn bij het bekijken van onze video's. Onze video's zijn geen financieel advies. U alleen kunt bepalen hoe het beste uw vermogen kunt beleggen. U draagt zelf de risico's van uw keuzes. Bekijk onze website: https://www.hollandgold.nl
De #1 Podcast voor ondernemers | 7DTV | Ronnie Overgoor in gesprek met inspirerende ondernemers
Wat was de grootste fuck-up die plaatsvond bij Picnic tot nu toe? Hoe breidt Picnic uit naar het buitenland, hoe zien zij hun rol als werkgever en hoe gaan ze om met duurzaamheid? Dat en meer in deze. compilatie van een gesprek dat 7DTV had met de CEO van Picnic, Michiel Muller. ⚡ 7DTV | YOUTUBE EN PODCAST KANAAL VOOR ONDERNEMERS | 1000+ INTERVIEWS | 2 NIEUWE VIDEO'S PER WEEK ⚡ 7️⃣ Abonneer je nu op het YouTube-kanaal van 7DTV voor meer video's: https://7dtv.link/YT
De Ondernemer stond dit keer geheel in het teken van MVO. Bijna acht op de tien mkb-ondernemers is bezig met maatschappelijk verantwoord ondernemen (MVO). Ongeveer de helft van de mkb-ondernemers vindt dat investeren in MVO goed is voor hun bedrijfsreputatie. Daarom staat De Ondernemer geheel in het teken van MVO. De KVK heeft in haar ondernemerspanel uitgebreid onderzoek gedaan naar maatschappelijk verantwoord ondernemen. De conclusies in de intro van dit artikel komen uit het onderzoek, en met Rodrique Engering van de Raad van Bestuur van de KVK als co-host, werd er in De Ondernemer ingegaan op deze en andere conclusies en zijn er adviezen hoe je als ondernemer MVO binnen je bedrijf kunt toepassen. Verder waren Wouter Scheepens van MVO Nederland, Anne-Jaap Deinum van Fedet en Jeroen van Glabbeek van CM.com te gast. Nog meer duurzaamheid in deze De Ondernemer, met duurzaam camperverhuurder Goboony duurzaam in de serie De Ondernemer Onderweg en natuurlijk schoof onze vaste radiocolumnist Job van den Berg aan in de studio. Ditmaal koppelde hij Maatschappelijk Verantwoord Ondernemen aan zijn expertise, AI. Van 13:00 tot 14:00 uur sprak Jonathan van Noord in het kader van de Rabobank Kennismakers Campagne nog even door met experts Ronald Edel en Klaas Rijpsma over onder meer het Pensioenakkoord, de AOV, maar ook over inkomensverzekeringen, bijvoorbeeld als je bedrijf geraakt wordt door cybercrime. De Ondernemer is wekelijks op dinsdag van 11:00 tot 13:00 uur live te beluisteren op New Business Radio en is ook te zien, via de homepage van De Ondernemer, YouTube en Facebook.
De Ondernemer stond dit keer geheel in het teken van MVO. Bijna acht op de tien mkb-ondernemers is bezig met maatschappelijk verantwoord ondernemen (MVO). Ongeveer de helft van de mkb-ondernemers vindt dat investeren in MVO goed is voor hun bedrijfsreputatie. Daarom staat De Ondernemer geheel in het teken van MVO. De KVK heeft in haar ondernemerspanel uitgebreid onderzoek gedaan naar maatschappelijk verantwoord ondernemen. De conclusies in de intro van dit artikel komen uit het onderzoek, en met Rodrique Engering van de Raad van Bestuur van de KVK als co-host, werd er in De Ondernemer ingegaan op deze en andere conclusies en zijn er adviezen hoe je als ondernemer MVO binnen je bedrijf kunt toepassen. Verder waren Wouter Scheepens van MVO Nederland, Anne-Jaap Deinum van Fedet en Jeroen van Glabbeek van CM.com te gast. Nog meer duurzaamheid in deze De Ondernemer, met duurzaam camperverhuurder Goboony duurzaam in de serie De Ondernemer Onderweg en natuurlijk schoof onze vaste radiocolumnist Job van den Berg aan in de studio. Ditmaal koppelde hij Maatschappelijk Verantwoord Ondernemen aan zijn expertise, AI. Van 13:00 tot 14:00 uur sprak Jonathan van Noord in het kader van de Rabobank Kennismakers Campagne nog even door met experts Ronald Edel en Klaas Rijpsma over onder meer het Pensioenakkoord, de AOV, maar ook over inkomensverzekeringen, bijvoorbeeld als je bedrijf geraakt wordt door cybercrime. De Ondernemer is wekelijks op dinsdag van 11:00 tot 13:00 uur live te beluisteren op New Business Radio en is ook te zien, via de homepage van De Ondernemer, YouTube en Facebook.
De Ondernemer stond dit keer geheel in het teken van MVO. Bijna acht op de tien mkb-ondernemers is bezig met maatschappelijk verantwoord ondernemen (MVO). Ongeveer de helft van de mkb-ondernemers vindt dat investeren in MVO goed is voor hun bedrijfsreputatie. Daarom staat De Ondernemer geheel in het teken van MVO. De KVK heeft in haar ondernemerspanel uitgebreid onderzoek gedaan naar maatschappelijk verantwoord ondernemen. De conclusies in de intro van dit artikel komen uit het onderzoek, en met Rodrique Engering van de Raad van Bestuur van de KVK als co-host, werd er in De Ondernemer ingegaan op deze en andere conclusies en zijn er adviezen hoe je als ondernemer MVO binnen je bedrijf kunt toepassen. Verder waren Wouter Scheepens van MVO Nederland, Anne-Jaap Deinum van Fedet en Jeroen van Glabbeek van CM.com te gast. Nog meer duurzaamheid in deze De Ondernemer, met duurzaam camperverhuurder Goboony duurzaam in de serie De Ondernemer Onderweg en natuurlijk schoof onze vaste radiocolumnist Job van den Berg aan in de studio. Ditmaal koppelde hij Maatschappelijk Verantwoord Ondernemen aan zijn expertise, AI. Van 13:00 tot 14:00 uur sprak Jonathan van Noord in het kader van de Rabobank Kennismakers Campagne nog even door met experts Ronald Edel en Klaas Rijpsma over onder meer het Pensioenakkoord, de AOV, maar ook over inkomensverzekeringen, bijvoorbeeld als je bedrijf geraakt wordt door cybercrime. De Ondernemer is wekelijks op dinsdag van 11:00 tot 13:00 uur live te beluisteren op New Business Radio en is ook te zien, via de homepage van De Ondernemer, YouTube en Facebook.
An MVP is a minimal viable product - a product with enough features to attract early-adopter customers and validate a product idea early in the product development cycle. In this episode we're talking about your MVO, minimum viable offer. I'm loosely using product development methodologies to help you think through bringing a brand new offer to market as a solopreneur. In this episode: What makes a MVO minimal The point of an MVO (short answer: should I spend any more resources on this idea?) How to use the half-page business plan to build out your MVO Counting the ROI of your MVO Building for early adopters vs the general public Where to focus your iteration energy once your MVO is successful Navigating continuous improvement __ Sign up for 30 Days of Audio-Based Coaching Sign up takes 60 seconds. No sales call, no application form. Just emotionally intelligent strategic help when you need it. Visit oyfn.co/audio to start today. 30 DAYS OF AUDIO-BASED COACHING For 30 days you'll have access to Hailey inside a private Slack channel. There you can converse via audio and text message as often as you'd like for 30 straight days. I can help you solve business problems, instill new habits, become more comfortable in a new role, set boundaries, find breakthroughs where you're stuck, build new assets and SO MUCH MORE. ____ This podcast is brought to you by One year from Now. You can find more podcast episodes, begin working with me through The Residency or 30DABC or download my free One Year from now vision workbook all at oyfn.co. Listen to to this episode on your favorite podcast player (Apple Podcasts, Spotify, you get it) or on on my website: oyfn.co/podcast
In deze aflevering interviewt Annette van Soest PvdA-Europarlementariër Lara Wolters over de nieuwe wetgeving maatschappelijk verantwoord ondernemen en de Brusselse lobby.Koffieplantages waar slavernij plaatsvindt. Corruptie bij Shell in Nigeria. Landroof en marteling bij de bouw van een Heineken-fabriek in Ethiopië. Follow the Money toonde meermaals aan dat multinationals het niet altijd even nauw nemen met de bescherming van mens en milieu.Er liggen momenteel twee voorstellen op tafel om bedrijven die bij dit soort wanpraktijken betrokken zijn aansprakelijk te stellen. In Nederland is dat de initiatiefwet Internationaal Maatschappelijk Verantwoord Ondernemen (IMVO). De Europese versie heet Corporate Sustainability Due Diligence Directive.Europarlementariër Lara Wolters (PvdA) diende het voorstel in voor de Europese regelgeving. En dat bracht nogal wat teweeg. ‘Iedereen in Brussel is ermee bezig of is hierop aangeslagen,' zegt Wolters in deze aflevering van Follow the Money interviewt. En dat betekent ook dat ze van alle kanten wordt gevraagd om ‘kopjes koffie te drinken' met belangengroepen. ‘De lobby op dit onderwerp is extreem.' Tot welke excessen een sterke lobby kan leiden, maakte ze van dichtbij mee. Haar fractiegenoot Eva Kaili zit al sinds december vast op verdenking van omkoping, in de zaak die bekendstaat als Qatargate. Kaili probeerde ook Wolters te manen om haar kritiek op Qatar te matigen: ‘Kaili heeft zeer haar best gedaan om mij te beïnvloeden. Ze ging nog net niet voor mijn microfoon liggen in de plenaire zaal.'De artikelen die in de uitzending aan bod komen vindt u hier:VVD-handelsminister hielp bedrijfslobby tegen aanpak kinderarbeid en milieuschade: https://www.ftm.nl/artikelen/vno-lobbyde-samen-met-huidige-minister-tegen-ketenaansprakelijkheidVan slavernij beschuldigde Braziliaanse koffietelers doen ongehinderd zaken - met steun van Nederlandse banken: https://www.ftm.nl/artikelen/van-slavernij-beschuldigde-braziliaanse-koffietelers-doen-ongehinderd-zaken-op-de-wereldmarkt-met-steun-van-nederlandse-bankenCorruptiezaak in Nigeria blijft Shell achtervolgen: https://www.ftm.nl/artikelen/corruptiezaak-nigeria-blijft-shell-achtervolgen
Notes for the show are below some of the links, but I focus on $GOOG $AMZN $MSFT $NVDA $AMD $DIS $NFLX $CPRI $HD $PEP $KO $PYPL $LYFT $EXPE $EQT In Mexico - the show is sponsored by $MELI - what a killer stock. In the US - the show is sponsored by Carvana $CVNA SPONSORED BY VISIBLE - Check out this page: https://www.visible.com/get/?3MFGCRG, it has all the info you need to know about joining Visible. When you use my friend code, 3MFGCRG, you'll get your first month of service for $20-off! Use code DSP25 for 25% off Trendspider's platform - https://trendspider.com/?_go=gary93 Please use this link as I do get a commission when you sign up, but it's the program I use my algorithm in and I'll give you access to the algorithm if you sign up through this link. I will also give you watch lists and my custom scans that I use in the podcast every day. Sign up for Webull and get free stocks like I did - WEBULL LINK Support the podcast - HERE Social Links and more - https://linktr.ee/dailystockpick NOTES $aa for Brian from YouTube Travis Facebook - Iqiyi? Thoughts? $stla for Tom $lyft - any reaction is an over reaction - but just be aware they are getting their ass handed to them by Uber - Lyft could very well go under if Uber continues to dominate $unh was a final trade last night at $485 saying it's just too cheap here $coin - big move down Watched Ricky last night …. He said he lost $5k yesterday on going in $tqqq and missing $sqqq …. Interesting strategy of using qqq to look at clear directions Charlie's ai plays $gfai - $.11 to $.77 - 2 long term contracts in Thailand $soun $bbai $ai $veri $mark $soxl vs $soxs $bac - consumers are spending more in January according to their survey $coin $GS - estimates oil will stay around $80 for the year $tsla investor day March 1 The g in chatgpt is not google … it stands for ChatGPT (Chat Generative Pre-trained Transformer - it does use Google's api to train but I was wrong $RGTI for Sherry SCANS $BA - not super strong $HLT - already moved $CTRA $VOC - like the chart - ex dividend was just 2% paid out on Jan 30 $MVO is similar and had a cross up as well $EQT - as stated yesterday RECAP Mon SCANS $SDOW $JPM $SPG Tue SCANS $SARK $SPXU $SDS $KHC Wed SCANS $MRK $NVDA $WFC $LAC $VUG $XLV $XLF $LYFT $AMGN $TRV $CEG $IDXX $WDAY $BK $CRK --- Support this podcast: https://anchor.fm/dailystockpick/support
Vandaag het gesprek met Maurice Beijk. Met “GROEN=DOEN, met nadruk op DOEN' vertelt Maurice Beijk over volhoudbare ontwikkelingen om ons heen en dit hoeft allemaal niet duur en complex te zijn. Maurice Beijk wordt als ‘Rentmeester2050' gezien als deskundige op het gebied van MVO en in het bijzonder op het gebied van duurzaamheid. Een van zijn statements is: “De aarde heeft ons niet nodig maar wij de aarde. Bij maatschappelijk verantwoord ondernemen (MVO) staan de 3 P's centraal: aandacht voor People, Planet en Profit. Bij MVO zijn de 3 P's daarom allemaal even belangrijk. Aan de drie P's van duurzame ontwikkeling: People, Planet, Profit, voegt hij een vierde P toe: Passie. “Zonder passie komt het er niet van” aldus Beijk. Omdenken is zijn kracht. Laten we beginnen… In gesprek met Maurice leerde ik: Als er een branche is waar je betekenisvol kunt zijn, dan is dat bouw infra wel. Meer dan 40% van de klimaatverandering komt door de manier van werken in de bouw en infra 30% van de energie, 30% van de materialen mondiaal. Zijn vouw heeft haar carrière ondergeschikt gemaakt aan die van Maurice, om hem de ruimte te geven om tot wasdom te komen. ReijntenInfra was het eerste bedrijf dat de SDGs volledig omarmt hebben. In 2023 moeten we circulair aanbesteden, in 2030 moet de branche op 50% circulair zitten en in 2050 op 100%. Zijn huis is al 20 jaar gasloos, niet op riool aangesloten en het huis volledig gebouwd van gerecyclede materialen. Volhoudbare projecten. Zes speerpunten: vertrouwen, noaberschap, reciprociteit, cocreatie, natuur en mensinclusiviteit,en creativiteit en innocatie en dat op een integrale manier. De lineaire economie heeft de circulaire economie ontdekt. Met lineaire business modellen verkopen ze circulariteit, zoals de CO2 prestatieladder en BTW heffen over het verwijderen en hergebruik van materialen. Shell krijgt 2 miljard subsidie om CO2 die ze zelf produceren in de grond te blazen. Een koe in de natuur poept en piest niet op dezelfde plek, tegenover mestkelders waar poep en pies bij elkaar voor veel ammonia zorgt. We moeten naar de kringloop landbouw, de houtwallen weer terug en biodiversiteit. Ieder jaar willen ze met ReintenInfra 5% meer blauw en groen in hun werk hebben. De berm en de sloot, de biodiversiteit. Why - samen op weg naar een schoon 2050 How - de zes SDG'sWhat - de excellijsten die dit aantonen 'Design by coincidence' gebruikt bij de nieuwbouw in Borne , met 80% hergebruikte materialen, met BREEAM outstanding Koplopers zijn niet belangrijk. Je hebt volgers nodig. Pas als je genoeg volgers hebt, dan heb je een beweging. Het enigste dat ons als mens kan redden is de natuur. We moeten groen groeien, meer waardering voor de natuur en de natuur weer omarmen. Herplanten, natuurinclusief boeren en bouwen. Vertrouwen krijg je niet, dat moet je verdienen. Door je nek uit te steken, door richting te geven, door een handreiking te doen en door het gesprek aan te gaan. Recyclen staat heel laag op de 10R-model of de ladder van Lansink. Het begint met Refuse - reduce - rethink - re-use - repair- refurbish - remanufacture - repurpose ... op de een-na-laatste plek staat pas recycle. Mensen die iets ontwerpen (architecten, constructeurs) die hebben een verantwoordelijkheid, die moeten het dusdanig ontwerpen dat het eindproduct weer in de keten behouden kan worden. Er zijn veel huizenfabrieken in Nederland en een deel daarvan zijn de afvalbergen voor de komende jaren. Net als de weg is ook een huis te gast in het landschap. Het voordenken is belangrijk hierin. Van fast fahion naar slow fashion. Van fast bouwen naar slow bouwen Circulariteit is het beheren en beheersen van de bronnen, energie-, voedsel-, materiaal-, ambachts-, en waterbronnen. In zo klein mogelijke kringlopen en de kringlopen gesloten houden. We moeten reclame verbieden - Jan Rotmans. Maurice gunt iedereen een goede crisis.
Larry Fitzgerald and Jim Gray celebrate world travel in honor of Tom Brady's Buccaneers beating the Seahawks in Germany. Then, they get into the WILD Vikings/Bills game and Justin Jefferson's all-time great catch. Mike McCarthy made another questionable call in the Cowboys loss to the Packers. They give their reactions to Jeff Saturday's debut as interim head coach of the Colts, and Derek Carr's emotional reaction to the Raiders loss. And finally, Larry names his top five in the MVP race.
This week, please join authors Qiang Zhang and Matthew Burrage as well as Senior Associate Editor Victoria Delgado as they discuss the article "Artificial Intelligence for Contrast-free MRI: Scar Assessment in Myocardial Infarction Using Deep Learning-Based Virtual Native Enhancement." Dr. Carolyn Lam: Welcome to Circulation On the Run, your weekly podcast summary and backstage pass to the journal and its editors. We're your cohosts. I'm Dr. Carolyn Lam, associate editor from the National Heart Center and Duke National University of Singapore. Dr. Peder Myhre: And I'm Dr. Peder Myhre from University of Akershus University Hospital in Norway. Dr. Carolyn Lam: Peder, today's feature discussion is on AI for contrast-free MRI. Isn't that so cool, using AI to perhaps understand what we could see only with contrast, but now in a contrast-free manner. Now I know that sound a bit confusing, but I hope very, very enticing, because everyone's going to have to wait for a little while before we get to that interesting feature discussion. And for now, let's talk about some of the papers we have in today's issue, shall we? Dr. Peder Myhre: Yes, Carolyn, I can't wait for the feature discussion, but we're going to start with some of the other papers in this week's issue, and we're going to start in the world of preclinical science with a paper looking at human cardiac reprogramming, because Carolyn, direct cardiac reprogramming of fibroblasts into cardiomyocytes has emerged as one of the promising strategies to remuscularize the injured myocardium. Yet it is still insufficient to generate functional induced cardiomyocytes from human fibroblasts using conventional reprogramming cocktails and underlying molecular mechanisms are not really well understood. Transcriptional factors often act in concert and form tightly controlled networks featuring with common targets among different transcriptional factors. Therefore, missing one component during heart development could lead to heart function defects and congenital heart disease. And in this study by corresponding author Yang Zhou from the University of Alabama at Birmingham, the authors perform transcriptomic comparison between human induced cardiomyocytes and functional cardiomyocytes to assess additional factors that govern transcriptional activation of gene programs associated with sarcomere contractility. Dr. Carolyn Lam: Wow. Really nicely explained. Thanks, Peder. So what did they find? Dr. Peder Myhre: So Carolyn, through these computational analysis of transcriptomic data, the authors identified TBX20 as the most under expressed transcription factor in human induced cardiomyocytes compared to endogenous cardiomyocytes. They also demonstrated that TBX20 enhances human cardiac reprogramming and improves contractility and mitochondrial function in the reprogrammed cardiomyocytes. Dr. Carolyn Lam: Nice. Could you summarize the clinical implications, please? Dr. Peder Myhre: Yes. So the clinical implications are that enhancing the efficiency and quality of direct cardiac reprogramming for human fibroblast is a critical step in the clinical translation of this technology, and better understanding of this synergistic regulation of key cardiac transcription factors during reprogramming will provide new insights into the genetic basis in normal and diseased hearts. Well, Carolyn, please tell me about your next paper. Dr. Carolyn Lam: Thanks, and we're moving now to kidney disease. Now end stage renal disease is associated with a high risk of cardiovascular events, but what about mild to moderate kidney dysfunction? Is it causally related to coronary heart disease and stroke? Well, today's authors give us a clue, and it's from corresponding author Dr. Di Angelantonio from University of Cambridge and colleagues who took a very unique combined approach to answer this question. They first conducted observational analyses using individual level data from four huge population based data sources, namely the emerging risk factors collaboration, Epic CVD, Jillion Veteran Program and UK Biobank. Can you imagine this comprised almost 650,000 participants with no history of cardiovascular disease or diabetes at baseline, yielding almost 43,000 and 15,700 incident coronary heart disease and stroke events respectively during a 6.8 million person years of follow up. So huge observational study, which they then followed with a Mendelian randomization analyses using a genetic risk score of 218 variants for GFR and involving participants in Epic CVD Million Veterans Program and the UK Biobank. Dr. Peder Myhre: Wow, Carolyn, this is a topic that I think many of us have really been wondering and thinking about. The mild to moderate kidney dysfunction, what does it really mean? And what a beautiful study to answer this. So what did they find? Dr. Carolyn Lam: First, there was a U-shaped association of creatinine-based GFR with coronary heart disease and stroke with higher risk in participants with GFR values below 60 or more than 105 mills per minute per 1.73 meters squared. Mendelian randomization analyses for coronary heart disease showed an association among participants with GFR below 60, but not for those with GFR above 105. Results were not materially different after adjustment for traditional cardiovascular risk factors and the Mendelian randomization results for stroke were nonsignificant but broadly similar to those for coronary heart disease. So in summary, in people without manifest cardiovascular disease or diabetes, mild to moderate kidney dysfunction is causally related to the risk of coronary heart disease, highlighting the potential value of preventive approaches that preserve and modulate kidney function. Dr. Peder Myhre: Thank you, Carolyn, for such a great summary and an important result from that study. I'm going to now take us back to the world of preclinical science and talk about diabetic cardiomyopathy and exercise. And we both know that patients with diabetes are vulnerable to development of myocardial dysfunction, and that exercise, our favorite thing, for maintaining cardiovascular health, especially in patients with diabetes. And despite a wealth of evidence supporting that cardiometabolic benefits of exercise, the precise exercise responsive signals that confer the beneficial effects of exercise in cardiomyocytes to remain poorly defined. And previous studies have identified fibroblast growth factor 21, FGF21, a peptide hormone with pleiotropic benefits on cardiometabolic hemostasis as an exercise responsive factor. And in this study from Aimin Xu from the University of Hong Kong, the authors investigated a six-week exercise intervention program in FGF21 knockout mice and wild-type litter mates that all had diabetic cardiomyopathy induced by high fat diet and injection of streptozotocin. Dr. Carolyn Lam: Nice. So what did they find? Dr. Peder Myhre: Yeah, the authors found that exercise lowers circulating FGF21 levels, therefore remodeling the heart as an FGF21 sensitive target organ. And the protective effects of exercise against diabetic cardiomyopathy are therefore compromised in mice with deficiency of FGF21. They also identified Sirtuin-3 as an obligor downstream effector on FGF21, preserving mitochondrial integrity and cardiac function. Finally, the authors demonstrated that FGF21 induces Sirtuin-3 expression through AMPK-FOXO3 signaling access. Dr. Carolyn Lam: So could you put that together for us better? So what are the clinical implications? Dr. Peder Myhre: So the clinical implications from this paper is that circulating FGF21 is a potential biomarker for assessment of exercise efficacy in improving cardiac functions. And exercise is a potent FGF21 sensitizer in cardiomyocyte and has the potential to enhance the therapeutic benefits of FGF21 analogs in diabetic cardiomyopathy, and selective activation of FGF21 signal in cardiomyocytes may serve as exercise mimetics and represent a promising targeted intervention for precise management of diabetic cardiomyopathy. Dr. Carolyn Lam: Oh my goodness. That is fascinating. Thank you, Peder. Well let's wrap up with what else there is in today's issue. There's an On My Mind paper by Dr. Weir entitled, “The Emperor's New Clothes: Aren't We Just Treating Grades of Heart Failure with Reduced Ejection Fraction.” Dr. Peder Myhre: And there is a Research Letter by Dr. James Martin from Baylor College of Medicine entitled “Gene Therapy Knockdown of Hippo Signaling Resolves Arrhythmic Events in Pigs after Myocardial Infarction.” Dr. Carolyn Lam: Very nice. Thanks, Peder. So wow, let's go onto a featured discussion on AI for contrast-free MRI and a virtual native enhancement here coming right up. Dr. Peder Myhre: Awesome. Dr. Carolyn Lam: Now we all know that myocardial scar is currently assessed non-invasively using cardiac MRI with late gadolinium enhancement as what we would call the imaging gold standard. Wouldn't it be amazing to have a contrast-free approach, which could provide the same information with many advantages such as a faster or cheaper scan, and without contrast associated problems? Well guess what? We're about to discuss that today in a feature publication in today's issue, and I am so pleased to have the co first authors with us today. They are Dr. Qiang Zhang and Dr. Matthew Burridge, both from University of Oxford, and to discuss it as well, our senior associate editor, Dr. Victoria Delgado from Barcelona. So welcome, everyone. Qiang Zhang, could I start with you and ask you, I understand you're a machine learning expert, which means you're probably smarter than all of us here. Could you maybe explain in simple terms what made you and Dr. Burridge do the study? Dr. Qiang Zhang: First? Thank you so much, Carolyn and Victoria, for the invitation. As you have mentioned, late gadolinium enhancement, or LGE, has been the imaging gold standard in clinical practice for myocardial catheterization including scar assessment for patients with myocardial infarction. However, LGE requires the injection for gadolinium contrast, and this is cautioned in some patient groups and increases the scan time and cost. On the other hand, pre-contrast CMR such as Sydney T1-T2 mapping, a gadolinium-free alternative for myocardial catheterization. But their clinical use has been hindered by confounding factors and a lack of clear interpretation. So with our cross deceptor team at Oxford, we developed an artificial intelligence, virtual native enhancement technique VNE. It can produce a sort of a virtual LGE image but without the need for gadolinium contrast. And we have previously tested it in patients with hypertrophic cardiomyopathy as published in this journal last year. And in this new study together with Matt here, we tested in patients with history of chronic or prior myocardial infarction. Dr. Carolyn Lam: Oh wow. Cool. So audience, you heard it. Instead of LGE, we now have VNE, virtual native enhancement. That's super cool. Thank you. Matt, could I bring you in here? So tell us a little bit more about the population you studied and what you both found. Dr. Matthew Burrage: Yeah, absolutely. And thank you so much for the invitation as well. So as Chang has said, this was a single sensor study that we performed at the University of Oxford and specifically targeting assessing myocardial scar in patients with a history of chronic or prior MI. So we had two sources for our population data. Well, first we used our real world clinical service data from our institution. So we screened 11 years worth of patient data for presence of MI. So patients were included. There was a evidence of a previous MI based on an ischemic pattern of LGE, but we specifically excluded patients who had an acute presentation, or if there were features of acute MI on the CMR scan such as presence of myocardial edema or microvascular obstruction. The reason for this is we wanted to keep this as a clean population to avoid the potential confounding effects of myocardial edema or MVO on native T1 values. And so we also excluded other myocardial pathologies such as underlying cardiomyopathies and infiltrative diseases. A second population dataset came from the OX Army study, which is a single center prospective study of patients presenting with acute MI. And for these patients we used their six month follow up scan to again avoid the confounding effects of edema and pathology. So overall we had a total of 912 patients who have contributed over 4,000 image data sets. The patient characteristics, 81% were male, they had a mean age of 64 years and there were cardiovascular risk factors such as diabetes melitis, hypertension, hypercholesterolemia in 20 to 40% of patients, while just over half had a history of previous revascularization. We also separately applied the VNE technology to a pig model of myocardial infarction, which was thanks to our collaborator, Rohan Domakuma in the US. And so those were scans performed eight to nine weeks after an induced MI in the LAD territory in a series of pigs. And so this gave us the ability to provide a direct comparison between LGE, VNE, and histopathology in this model. Dr. Carolyn Lam: Wow. And results? Dr. Matthew Burrage: So what we found and the key results were firstly that VNE provided significantly better image quality than LGE, and this was on blinded analysis by five independent operators from our test data sets. Secondly, the VNE correlated strongly with LGE in terms of quantifying infarct size and the degree of transmurality, so the extent of the MIs in our test data set. We had pretty good overall accuracy of 84% for VNE in detecting scar compared to LGE with no false positive VNE cases. And finally there was also excellent visuospatial agreement with the histopathology in the pig model of myocardial infarction. So really this, we think, is a technology that provides clinicians with images in a format that firstly they're familiar with, which looks like LGE, provides essentially the same information as LGE, but it can be achieved without the need for any gadolinium contrast agents and can be acquired in a fraction of the time. So it takes less than one second to generate the VNE image. So as we've said before, we feel there's a lot of potential here for this technology to potentially eliminate the need for gadolinium contrast in a significant proportion of CMR scans, reduced scan times and costs, increased clinical throughput and hopefully improve the accessibility of CMR for patients in the near future. Dr. Carolyn Lam: Oh wow. That is tremendous. So first of all, congratulations to both of you. Before I ask Victoria for some thoughts, could I also just check with Qiang Zhang, because all AI algorithms need to be externally validated or surely there's some catch to it, or so-called limitations, or something else you may study. Could you maybe round up by saying is there anything that clinicians should not be applying it to or be aware of some limitations or? Dr. Qiang Zhang: Thank you, Carolyn. So a limitation of this study is that the dataset that is used for developing the models, the majority of them are patients around six month after the acute infarction. So where the myocardial infarction is still evolving, which may include residual edema and microvascular obstruction, and that is difficult to assess using the current VNE model. And also we found it challenging to assess small sub endocardial infarction and actually to address those limitations, we are working on improving the VNE models, training it on even larger data sets and training it on LGE to detect small sub endocardial function. And we will further develop it to detect, for example, acute edema and a microvascular obstruction, and in the meantime develop quality control driven AI models to inform the clinical users of and unreliable results. Dr. Carolyn Lam: Wow, thank you. So Victoria, now I'm dying to hear your thoughts. How do you think this fits in the landscape of all AI imaging now? Dr. Victoria Delgado: I think that it's an excellent development and I congratulate the others for the article and the proof of concept that we can move away from the late enhancement and the use of gadolinium enhancement. I think that this is a major step forward because as Matt said, they are going to decrease very much the time of scanning and the post processing because is automatically done as far as I understand. So even if you can interpret yourself the amount of so-called virtual enhancement, the system gives you a value for that extension of the virtual in non-gadolinium enhancement. So that reduces very much the variability that can be in each observer if that is done automatically. But my question to them is also if that can be influenced by the type of scanner that you use, for example on echocardiography, that's much more my field of interest, it depends very much sometimes how the images are processed of which are the vendors that we have used to acquire the images. Is this a limitation for your software? Can you foresee there some variability or is completely independent? Dr. Qiang Zhang: Thank you, Victoria. So we are aware of actually the difference of the data produced by different scan of vendors and the advantage of AI-driven methods is that it is data driven. So we plan to incorporate dataset from other vendors so that the trend that VNE models can work with like multiple scanner vendors. This actually will be done alongside the ongoing standardization program of T1 mapping in our group, which is the underpinned technology for VNE. And this is led by Professor Stephan Pitchnik and Vanessa Farrera. And we actually hope the VNE technology as AI driven methods could contribute to a solution to the CMO standardization between the scanner vendor. Dr. Victoria Delgado: And another question, if I may follow in this CMR, it has been proposed as a very valuable imaging technique to assess infarct size and to see the efficacy of some therapies to reduce the myocardial infarction size. How do you think that this new methods will impact in future trials and the way we have been interpreting the previous trials, like for example, the one that you use for the validation? Dr. Matthew Burrage: Yeah, thanks Victoria. It's a really, really excellent question. I think there's a lot of potential for the new VNE technology to also become a clinical endpoint in some of these trials in terms of reduction in infarct size, because the information that we get is more or less the same as we get from the LGE. So there's lots of potential that we can, again, use this as a biomarker in trials for looking at reduction in infarct size and reperfusion therapies. But it has the benefit that it can be done quicker and without gadolinium contrast. Dr. Victoria Delgado: This is amazing guideline and really I would have a lot of questions for them as well. And knowing the literature, for example, in the Scenic center in Madrid that they have been scanning the evolution of myocardial infarction from 0.02 weeks to see how this would translate with your technique. That will be amazing to understand how this can be done. Dr. Carolyn Lam: Oh wow, there you go. New research idea right there. Well how about if we end with a very quick question for each of the first authors. So maybe Matt, you could start, I mean is this ready for primetime and clinical use? And if it's not, what needs to be done to get there? In other words, where are you headed as the next step? Dr. Matthew Burrage: So again, thank you, Carolyn, that's a really excellent question and I think the next step before this becomes ready for primetime clinical use is validating this technology really across the spectrum of other myocardial pathologies. So the next work that we are developing this on is in patients with acute myocardial infarction, and then extending this to sort of acute inflammatory conditions like myocarditis, other non-ischemic cardiomyopathies, things like amyloidosis as well. So this will be the next step into rollout and we are looking to track things like VNE burden and how that relates to clinical outcomes, similar to the previous LGE papers have done across different myocardial pathologies, but then ultimately aiming towards clinical rollout within the next few years. Dr. Qiang Zhang: Yeah, I think pretty much what Matt has said, we're going to develop the deep learning methods and test it further on pretty much the whole spectrum of commonly encountered diseases, and then more complex pathologies such as acute pathologies like edema, microvascular obstruction, and then we test on large population study like UK Biobank and other prospective clinical trials. And of course the most importantly is to roll out for real world clinical use. And as Matt said, we are aiming to do this within the next two to five years. Dr. Carolyn Lam: Wow, this is amazing. Both Victoria and I said thank you, congratulations on this landmark piece of work. Thank you for publishing it in circulation. Audience, thank you for joining us today from Greg, Peder, myself. You've been listening to Circulation on the Run, and don't forget to tune in again next week. Dr. Greg Hundley: This program is copyright of the American Heart Association 2022. The opinions expressed by speakers in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more, please visit ahajournals.org.
Angelo is joined by Lex and MVO for a heavy cope session. The guys talk about whether this situation was predictable, who is to blame, and where each guy goes from here. Plus, some quotes from Errol Spence, information about this new streaming service that has seemingly come from nowhere, and more.
In the third hour of Tuesday's show, Rob and Ed are joined by Amy Lawrence of After Hours on CBS Sports Radio. Amy shares her thoughts on the NFL season thus far and which teams have disappointed and surprised through 4 games. Switching gears back to baseball, Rob and Ed look back on the O's 2022 campaign. Adley was the MVO for '22 but what about the Most Improved Oriole? Continuing with the O's, Baltimore Baseball Tonight's Jim Hunter joins the show to share his thoughts on the Birds season as it comes to a close. The Commish's Baltimore closes out hour three, with Ed telling a story about his first job in college. The guys also recap their picks for week 4 and look at the standings.
MVO Uncensored Rundown: ⁃ When Da Baby drops, MVO did not stop. Da Baby went double wood even after tryna use Megan for clout. When is he gonna get shot to resurrect his career? ⁃ Nicki Minaj vs Cardi B again! ⁃ Who has the better future? Ice Spice or Coi Leray? ⁃ Is Al Cood a munch? ⁃ Which hip hop tracks get you in your feelings? ⁃ RIP Coolio. Gangsters Paradise or Keenan and Kel ⁃ Is Al Cood the Sway of MVO? He got the answers! ⁃ Spence vs Crawford, Tank vs King Ry ⁃ How's the big fella holding up after his tumble down the stairs?
૧૯૭૧થી ઓસ્ટ્રેલિયાના સૈન્યમાં જોડાનાર ડૉ મધુ પટેલનું તેમની 50 વર્ષની સેવા બદલ ચીફ ઑફ આર્મી લેફ્ટનન્ટ જનરલ રિક બર AO, DSC, MVO દ્વારા સન્માન કરવામાં આવ્યું હતું. પાંચ દાયકાની તેમની કારકિર્દીમાં તેમણે અનેક આર્મી યુનિટ અને રેજિમેન્ટમાં કામ કર્યું છે. સિત્તેરના દાયકામાં ઓસ્ટ્રેલિયાના સૈન્યમાં જોડાવાનો અનુભવ કેવો રહ્યો તેના વિષે ડૉ મધુ પટેલે SBS Gujarati સાથે વાત કરી.
MVO Uncensored Rundown: ⁃ What celebrity couple would absolutely shatter the internet if they got together ? ⁃ The Game new album: hot or not? ⁃ Fat Joe sending shots at MVO? Macho! Raul! ⁃ The Big Fella gets cockblocked by his own homie! What happened to the wingmen of yesterday? ⁃ Charleston White gets a thug arrested. ⁃ Atlanta DA confirms a member of YSL has agreed to testify against Young Thug ⁃ New music from Meg Thee Stallion, Nicki Minaj and Rod Wave. Have you heard it? ⁃ Why you mad? Goddamn Asian restaurants!!! ⁃ Best Album Turning 15 This Year: American Gangster, Graduation, Curtis, The Cool, Underground Kingz, Buck the World, TI vs Tip, Shock Value, The Big Doe Rehab, From Nothin' to Somethin Fat Joe Dissses MVO The Game Album Review 50 Cent Final album care of listening? G Unit Reunion Album? No 50 says his back hurt from carrying them DR Dre and Snoop cooking up new music interested? Funk Flex is challenging Artist (Jada and Swizz to drop a bew collab was 1 challenge, Challenged Fab to drop new music) Drake Gets Face Tattoo (Would you ever get one if you were rich?) Will and Jada makes first appearence together since Oscar slap (I have a theory) Nipsey Recieves Star in Hollywood walk of fame how you feel about that?
https://hammeringdown.com/ Hello! In this episode, I discussed the Hartford Athletic match and I have some strong feelings about it. It was one frustrating night that was cured by MVO, Marlon, and Enzo. Does that mean I'm excited about the 3 points? Sorta. But it has left me more frustrated than anything. If you did enjoy, follow me on Twitter @KaylorHodges --- Support this podcast: https://anchor.fm/hammering-down/support
MVO Uncensored Podcast Rundown: ⁃ Desus and Mero broke up. Is MVO next? ⁃ Flex vs Griselda and Pete Rock ⁃ The days of the super thug is over. All hail Mase , 69, Charleston White and Funk Flex ⁃ Orlando says Bow Wow got good pussy. I beg your pardon ⁃ MVO's Mook of the Week ⁃ Hip hop albums and tracks that dropped since our last episode: Joey Badass Zipcodes, Where I Belong and Survivor's Guilt, Latto Pussy, Cardi B Hot Shit featuring Durk and Ye, ⁃ Al Cood went to the Bahamas. Did he get any Bahamas mamas ⁃ The Big Fella got fired on vacation. Wait what? ⁃ Complaints and grievancees
Angelo welcomes back MVO back to the podcast to break down Ryan Garcia's victory over Javier Fortuna. Garcia was impressive enough, but was it enough to put him on equal ground with Gervonta Davis and the rest of the other lightweights. Plus, they discuss whether or not Tank will indeed by Ryan's next fight? Plus, a quick look at the undercard, looking forward, and catching up with what's happened in the world of boxing since we last heard from MVO. Get access to our patreon which has more pods and our exclusive chat over at patreon.com/sundaypuncher
When you're about to embark on a big transition, do you work with a coach in the planning stage, when you've already quit one thing and want to build another, or afterwards?We also talk through MVO - the minimum viable operation - and how it can help tone down the overwhelm of big changes.Book your free 1:1 consult with Ellen:ellenwyomingdeloy.as.me Learn more:www.ellenwyomingdeloy.comSupport the show
Benavidez-Lemieux fight card review, a shout out to Jamel Herring, and MVO may leave NYC for the Deontay Wilder statue unveiling... --- Support this podcast: https://anchor.fm/boxing-source-radio-show/support
Dave Chapelle Gets attacked Kevin Samuels Dies (Heart attack after spending the night a new chick you think she did for all the women he slandered?) Kendrick Drops a new joint Revisiting Kendrick “control” verse” Future album have you heard it? 2pac doc series “Dear Mama” Britney dropping a tell all book (what you expect in the tell all) Jack Harlow Album (Industry Plant or Nah?) Pusha T banned from Canada (Is it cuz he Ether'd Drake?) tranny benzino try to bad drops diss track (lets listen) Unpacking in Honor of Mothers Day “Sorry Ms Jackson” -Outkast Sports- Canelo L Joker MVP again you agree? Return of Slang Wars and MVO trivia, MVO'ers to battle each other
On Hour 2 of The Lookahead, Scott Seidenberg breaks down today's NBA action. Then Jonathan Von Tobel joins to analyze the NBA playoff picture as we look ahead to the final few games of the regular season. Scott also breaks down today's NHL action and finally Matt Youmans joins to analyze the wild college hoops National Championship game and look ahead to The Masters! See omnystudio.com/listener for privacy information.
EQxperiences from a west coast carrier, new MHA and, from a MVO. If you want to join in, email me at postalgonewild@gmail.com
The Uplifting Content Podcast With Ione Butler (Let’s Talk About…)
Debra Searle MVO, MBE Debra Searle is a professional adventurer and serial entrepreneur. Her expeditions have included rowing solo across the Atlantic and sailing around Antarctica. She has also launched four companies, is a published author, has worked as a presenter for the BBC and is a trusted corporate speaker. Debra's spirit of adventure gained her an MBE from Her Majesty the Queen and a place on the board of The Duke of Edinburgh's Award. She was later awarded an MVO in the 2014 New Year's Honours. In Spring 2015, Debra and her company combined her two passions for adventure and gender equality by organising and leading an all-female team on an expedition in the Arctic Circle. In this episode we spoke about: -Her story of the remarkable 111 days at sea rowing across the Atlantic - Her journey from being a PE teacher to launching 4 companies - How she manages her businesses and going on adventures. - The correlation between your thoughts, feelings and their impact on your actions - Choosing your attitude changes beliefs - How people don't push themselves outside of their comfort zone. - How to start your day the right way - How the speaking business works - How she overcomes her struggles and much more For a fantastic work sheet on goal setting you can get Debra's "Life Upgrade Guide" by following this link www.debrasearle.com/goals Sign up for my weekly(ish) email for all our giveaways and updates here. Ione Butler Facebook Instagram Twitter Podcast Website IMDB Uplifting Content Debra Searle Website Facebook LinkedIn Twitter YouTube Google +
Sean Anderson, Ricky Widmer, and Dave Oster discuss Anthony Davis' chance of winning the 2018 NBA MVP. Additional Topics: WET BOIZ 2018 NBA Draft: Best Team Fits For Marvin Bagley 2018 NBA Draft: Which Prospects Best Fit With The Grizzlies? (Recorded on: March 3rd, 2018) You can directly support Most Valuable Podcasts on Patreon. Become a patron for as little as $1/month to help us expand our great content for you. Also, if you can afford to pay a little every month, it really helps us to continue producing great content. ------------------------------------ Snapchat: mostvaluablepod Twitter: twitter.com/MostValuablePod Facebook: www.facebook.com/mvpsportsnetwork Patreon: patreon.com/mostvaluablepodcasts