In the Know

Professor Matt Kaeberlein is an outspoken proponent of rapamycin, and pretty skeptical about virtually all the other interventions people talk most about. Here he lays out a pretty complete and persuasive model for why and how aging happens at all, and why some approaches are most likely to work.

This founder has been part of so many of the exciting longevity startups, investments, and discussions that you simply must understand the world the way he sees it before taking a view about life extension. In this episode, you will.

One of the more incredible research programs in longevity is regeneration: rebuilding and replacing failing organs with lab-grown cells. Jean Herbert at Einstein is working on regenerating your brain.

A rare MD at the cutting edge of the longevity field, Dr. Barzilai heads the Institute for Longevity Research at Einstein. We cover his unique contributions, especially the currently buzzy topic of metformin, as well as his work on the genetic luck of centenarians.

Longevity superstar alert. A deep dive with one of the most recognized and longest-serving visionaries of longevity world.

The easy way to attack Parkinson's? A neuron-by-neuron model of the brain.

My friend Sergey Young -- private equity investor and founder of the Longevity Vision Fund -- joins me to talk about his book "Growing Young". Get it here http://www.sergeyyoung.com

Started a long way off in Pakistan, made it to Princeton among the great inventors of the Internet, and now building the New Internet.

CEO of the ultra-hot cloud data company Snowflake — and former CEO of huge enterprise tech players ServiceNow and DataDomain

One of my favorite writers, Stacy Schiff has written a bunch of amazing biographies. This time we talk about how women are remembered in history.

Bari Williams is a unicorn in the tech sector: high-ranking, high-achieving African-American woman. We talk about why Silicon Valley is so dysfunctional on diversity.

He also talks about finishing Gaudi’s La Sagrada Familia, the Sydney Opera House, Centre Pompidou in Paris, the longest bridge in the world and so much more.

See if you can notice where tears start streaming down my face.

David Klein started Common Bond because grad school was too expensive. He went from McKinsey and Corporate America to homeless as he scratched together Common Bond, which now serves over 100,000 people in their mission to make higher ed cost

Amol Sarva (Knotel cofounder) takes In the Know to learn how to make things big…and how to keep things small. The wine community founded by Heini Zachariassen blew up, slowly. A few uses to a few millions daily. Bonus: learn

Amol Sarva (Knotel cofounder) takes In the Know to talk with with the angel and founder Fabrice Grinda about his 100s of startup experiences and mainly about systems — the system for selecting the right businesses for Fabrice, originally his

Amol Sarva (Knotel cofounder) takes In the Know to talk with Alex Mashinsky who has repeatedly dreamt big and hit big using information networks to disrupt telecom, Wall St, banks, taxis, and more. Listen to the visionary founder of Arbinet,

Amol Sarva (Knotel cofounder) takes In the Know to talk with Will Herman, the Boston founder who dropped out of college, started at Digital Equipment Corporation in the hallowed early days of computing and followed his destiny to 100s of

Amol Sarva (Knotel cofounder) takes In the Know to visit Dane Madsen in a conversation that finds him far away from the centers of the commerce, in his retreat, talking travel, transformation, teams, and asking why.

Amol Sarva (Knotel cofounder) takes In the Know to visit Anthemos Georgiades who studied classics at Oxford, worked for BCG, joined Harvard Business School, and used it to launch his clever plan to to transform apartment rentals: Zumper. First time

Amol Sarva (Knotel cofounder) takes In the Know to visit Safi Bahcall who studied physics at Princeton as a kid with Stephen Wolfram, started a cancer drug discovery company and took it public, advised the Obama White House on science

This time on In the Know Amol Sarva (Knotel cofounder) is visiting with a podcast media master strategist, Shira Atkins — creator of the fabulous series that followed the 2018 elections and first-time women candidates, “Women Belong in the House”,

This week In the Know has Amol Sarva (cofounder of Knotel) and colleague Allison Stoloff (Knotel’s head of revenue marketing) visiting with Martha Stewart for an all-topics, all-opinions tour of her legendary business accomplishments and innovations.

This week In the Know comes to Amol Sarva (Knotel cofounder) at Knotel HQ, where legendary producer, composer and musical technology inventor Money Mark drops in. Sure he produced the Beastie Boys for nearly 20 years, and yes it was

In the Know follows Amol Sarva (Knotel cofounder) into a lengthy face-to-face with the legendary scientist, inventor, polymath and CEO Stephen Wolfram. The creator of Mathematica, Macarthur genius, Richard Feynmann disciple, computer science experimentalist, and on and on is also

At the 2019 South by Southwest, Amol Sarva (Knotel cofounder) moderated a panel with the fabulous CEO of Venture For America, Amy Nelson, as well as Upwork’s Head of Public Affairs, Mike McGeary, and Claire Vo of Optimizely. The topic: