Podcast appearances and mentions of George Church

"My ideas are often labelled as impossible, or useless, or both. Usually when people say that I'm on the right track."George Church is a geneticist, molecular engineer, and one of the pioneers of modern genomics. He's also someone who makes a habit of finding solutions to the seemingly impossible.Over the course of his career so far, George developed the first method for direct genomic sequencing, helped initiate the Human Genome Project, and founded the Personal Genome Project: making huge quantities of DNA data publicly available for research. Today, as a professor at Harvard Medical School and MIT, he's working on some of the most headline-grabbing - and controversial - science on the planet: from the so-called "de-extinction" of woolly mammoths, to growing transplant-suitable organs in pigs, to virus-proofing humans.When inspiration strikes, there seems to be little that will slow him down - even the fact that he has narcolepsy, the neurological disorder that causes sudden sleep attacks. In fact, as George tells Professor Jim Al-Khalili, some of his best ideas come in those moments between waking and sleep...Presented by Jim Al-Khalili Produced by Lucy Taylor for BBC Studios

Get started with 1 month free of Superhuman today, using my link: https://try.sprh.mn/briankeating Today's guest made bacteria immune to every virus that exists. This breakthrough could revolutionize medicine by creating virus proof cell therapies and potentially extending this protection to human cells. Also demonstrating that we can fundamentally rewrite the language of life itself, something that was previously thought impossible. George Church is a Harvard Medical School genetics professor and pioneer of synthetic biology. He's an entrepreneur who's found in multiple biotech companies and is known for pushing the boundaries between science fiction and reality. His team just did something that sounds like pure science fiction. They made living cells completely immune to every virus on Earth. That resistant immune, every single virus that tries to infect your cells just fails. The viruses can't evolve around it. Here's the wild part. They didn't add anything new. They just removed a few letter from the genetic alphabet. But George isn't stopping there. He wants to do this to human cells. He's talking about engineering astronauts for Mars missions, bringing back wooly mammoths, and maybe even, just maybe, making humans virus proof to the implications are staggering. The ethics are murky. And the timeline. Well, if church's track record tells us anything is happening far faster than we think. KEY TAKEAWAYS 00:00:00 – Church's team made cells virus-proof, a major medical breakthrough 00:02:34 – Radiation resistance may come from DNA repair linked to desiccation 00:04:43 – A few genes can boost bacteria's radiation resistance 00:07:16 – Panspermia is unlikely due to harsh space conditions 00:10:50 – Space travel may need biological, not just physical, changes 00:14:19 – Regenesis explores synthetic biology's potential 00:18:19 – Height involves many genes, but single ones can have big effects 00:20:57 – Once sci-fi, genome sequencing and pig organs are now real 00:23:20 – Church and Venter are more collaborators than rivals 00:27:17 – Rewriting genes can create virus-proof organisms 00:35:36 – DNA can store data, but reading/writing is slow 00:41:06 – Gattaca and Jurassic Park portray genetics well with small flaws 00:44:03 – Gene therapies can be affordable for all 00:46:44 – Stem cells can create any body cell for therapy 00:49:15 – “Mirror humans” are possible but avoided ethically 00:53:59 – Genomic privacy isn't an issue since we shed DNA constantly 00:56:09 – Gene editing helps endangered species adapt, not revive extinct ones 01:00:30 – Virus-proof humans are possible, but tough to deliver to all cells 01:02:59 – Gene therapies could reverse aging at the cellular level 01:04:18 – Church avoids saying “impossible,” but admits to timeline optimism - Get My NEW Book: Focus Like a Nobel Prize Winner: https://www.amazon.com/dp/B0FN8DH6SX?ref_=pe_93986420_775043100 Please join my mailing list here

Nicki Panagopoulas joins the Morning Show to share all of the details for this weekends' events. Immerse yourself in the sounds of the bouzóuki, the tastes of authentic Greek cuisine, and the eye-catching sights of dancers streaming by in colorful costumes. Enjoy shopping for imported jewelry, gifts, foods and pastries. Learn about the changeless Orthodox Christian faith with a tour of our own St. George Church. Be happy and have fun! Na Zíse!See omnystudio.com/listener for privacy information.

Ben Lamm is CEO and Co-founder of Colossal Biosciences, the world's first de-extinction company. Colossal has raised more than $400 million at a valuation north of $10 billion to bring back extinct species using synthetic biology and genetic engineering. Just this year, the company unveiled the first dire wolves born in 12,000 years, created woolly mice with mammoth-like fur, and remains on track to see woolly mammoth calves by 2028.This conversation explores Colossal's end-to-end platform approach, from ancient DNA recovery to multiplex genome editing, and why Ben sees de-extinction not just as science fiction come true but as a venture-scale business that spins out companies, partners with governments, and raises profound ethical questions. We cover polarizing public reactions, the conservation potential of rewilding keystone species, and how synthetic biology and AI are accelerating breakthroughs once thought impossible.Episode recorded on Aug 20, 2025 (Published on Sept 23, 2025)In this episode, we cover: [04:14] An overview of Colossal[05:47] The company's dire wolf pups debut[10:51] Reasons behind de-extinction[11:49] Mammoth vs. thylacine vs. dodo challenges[18:40] How Ben co-founded a bioscience company[20:56] George Church and Colossal's origin story[22:40] The “why” behind bringing back the mammoth[27:42] Colossal's biodiversity credit carbon model[28:43] Trade-offs between rewilding existing species vs extinct[31:35] Colossal's multifaceted business model[33:58] The company's plastic-eating enzyme spinout[37:57] Colossal's unique speed of R&D[40:38] The Colossal Foundation[42:29] Ben's pov on our moral obligation to transparency Enjoyed this episode? Please leave us a review! Share feedback or suggest future topics and guests at info@mcj.vc.Connect with MCJ:Cody Simms on LinkedInVisit mcj.vcSubscribe to the MCJ Newsletter*Editing and post-production work for this episode was provided by The Podcast Consultant

What is de-extinction? The process of de-extinction is all about bringing extinct species back to life. It became known in the 2010s, thanks to an ambitious plan from American geneticist George Church, who dreamed of resurrecting the woolly mammoth, an animal which has been extinct for 3700 years. Fast forward to the 2020s and Church's bioscience startup Colossal is now eding closer towards making that a reality. As of March 2022, Colossal announced that it had raised a total of $75M for the project. Is it really possible to revive extinct animal species? Why would we want to bring extinct species back to life? How is the idea of de-extinction being received by the scientific community? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: ⁠What are happy hormones?⁠ ⁠What is erectile dysfunction?⁠ ⁠Who are Arcade Fire?⁠ A podcast written and realised by Joseph Chance. First broadcast: 10/05/2022 Learn more about your ad choices. Visit megaphone.fm/adchoices

Jeffrey Epstein had a deeply unsettling fascination with transhumanism, a fringe scientific ideology focused on using advanced technologies like genetic engineering and artificial intelligence to “improve” or even transcend the human species. For years, Epstein cultivated relationships with prominent scientists, funding research and hosting intellectual salons to promote his own bizarre vision of the future. One of his most disturbing ambitions was to “seed the human race with his DNA” by impregnating multiple women—reportedly as many as 20—at his Zorro Ranch property in New Mexico. Epstein described this vision to scientists and guests during private dinners and conferences, presenting it as part of a eugenics-inspired project to propagate his genes across humanity. He also expressed a desire to have his head and genitals cryogenically frozen in hopes of being revived later—a grotesque extension of his obsession with immortality.Epstein's involvement in the scientific world wasn't just casual philanthropy—it was a calculated attempt to embed himself within elite circles and launder his public image through academic legitimacy. He courted renowned figures like Stephen Hawking, George Church, and Murray Gell-Mann, using his money and influence to insert himself into high-level conversations on AI, neuroscience, and biology. Several of these scientists would later admit they were unaware of the depth of his criminal behavior during their interactions. Still, Epstein's promotion of transhumanist goals—particularly ones steeped in eugenicist thinking—raised red flags about the type of future he envisioned: one dominated by elite control, genetic manipulation, and the erasure of moral constraints in pursuit of technological supremacy.Become a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.

George Church is the godfather of modern synthetic biology and has been involved with basically every major biotech breakthrough in the last few decades.Professor Church thinks that these improvements (e.g., orders of magnitude decrease in sequencing & synthesis costs, precise gene editing tools like CRISPR, AlphaFold-type AIs, & the ability to conduct massively parallel multiplex experiments) have put us on the verge of some massive payoffs: de-aging, de-extinction, biobots that combine the best of human and natural engineering, and (unfortunately) weaponized mirror life.Watch on YouTube; listen on Apple Podcasts or Spotify.Sponsors* WorkOS Radar ensures your product is ready for AI agents. Radar is an anti-fraud solution that categorizes different types of automated traffic, blocking harmful bots while allowing helpful agents. Future-proof your roadmap today at workos.com/radar.* Scale is building the infrastructure for smarter, safer AI. In addition to their Data Foundry, they recently released Scale Evaluation, a tool that diagnoses model limitations. Learn how Scale can help you push the frontier at scale.com/dwarkesh.* Gemini 2.5 Pro was invaluable during our prep for this episode: it perfectly explained complex biology and helped us understand the most important papers. Gemini's recently improved structure and style also made using it surprisingly enjoyable. Start building with it today at https://aistudio.google.comTo sponsor a future episode, visit dwarkesh.com/advertise.Timestamps(0:00:00) – Aging solved by 2050(0:07:37) – Finding the master switch for any trait(0:19:50) – Weaponized mirror life(0:30:40) – Why hasn't sequencing/synthesis led to biotech revolution?(0:50:26) – Impact of AGI on biology research progress(1:00:35) – Biobots that use the best of biological and human engineering(1:05:09) – Odds of life in universe(1:09:57) – Is DNA the ultimate data storage?(1:13:55) – Curing rare diseases with genetic counseling(1:22:23) – NIH & NSF budget cuts(1:25:26) – How one lab spawned 100 biotech companies Get full access to Dwarkesh Podcast at www.dwarkesh.com/subscribe

On this episode, Richard Whillet unravels a deep web of connections stretching from Epstein's DNA experiments with George Church to the hidden agendas behind Palantir's role in the LA Riots and its $30M ICE contract. They dig into Epstein's mysterious New Mexico Zorro Ranch, rumored ties to Dulce Base, Trementina vaults, and Los Alamos. The conversation spirals into occult territory with the homunculus myths of Rosemary's Baby and Crowley's Moonchild, before surfacing in the elite playgrounds of St. Barts and St. Thomas—linking Epstein, Diddy, and Mike Jeffries. Finally, they dive into the powerful nexus of Chabad Lubavitch, Trump, Putin, and Netanyahu—and their vision for the “World to Come” (Olam Haba) Please subscribe to the new Tin Foil Hat youtube channel:  https://www.youtube.com/@TinFoilHatYoutube Check out Sam Tripoli new crowd work special "Black Crack Robots" now for free. https://youtu.be/_FKugOeYaLc Check out Sam Tripoli's 2nd New Crowd Work Special “Potty Mouth” on YouTube for free. https://www.youtube.com/watch?v=22j3Ds5ArjM Grab your copy of the 2nd issue of the Chaos Twins now and join the Army Of Chaos: https://bit.ly/415fDfY Check out Sam "DoomScrollin with Sam Tripoli and Midnight Mike" Every Tuesday At 4pm pst on Youtube, X Twitter, Rumble and Rokfin! Join the WolfPack at Wise Wolf Gold and Silver and start hedging your financial position by investing in precious metals now!  Go to samtripoli.gold and use the promo code "TinFoil" and we thank Tony for supporting our show. LiveLongerFormula.com: Check out LiveLongerFormula.com/sam — Christian is a longevity author and functional health expert who helps you fix your gut, detox, boost testosterone, and sleep better so you can thrive, not just survive. Watch his free masterclass on the 7 Deadly Health Fads, and if it clicks, book a free Metabolic Function Assessment to get to the root of your health issues. CopyMyCrypto.com: The ‘Copy my Crypto' membership site shows you the coins that the youtuber ‘James McMahon' personally holds - and allows you to copy him. So if you'd like to join the 1300 members who copy James, then stop what you're doing and head over to: CopyMyCrypto.com/TFH You'll not only find proof of everything I've said - but my listeners get full access for just $1  Want to see Sam Tripoli live?  Get tickets at SamTripoli.com: San Diego:  Sam Tripoli and Tin Foil Hat Comedy Live July 17th-19th https://americancomedyco.com/collections/sam-tripoli-live-july-17-19   Boston, MA:  Tin Foil Hat Comedy Night Headlines Nick's Comedy Stop  August 1st https://www.nickscomedystop.com/event-details/special-event-tin-foil-hat-comedy-with-sam-tripoli-and-eddie-bravo-live   Broadbrook Ct: Tin Foil Hat Comedy and Swarm Tank at 8pm on August 2nd https://broadbrookoperahouse.thundertix.com/events/246069   Please check out Richard Willet's internet: Website: https://www.ickonic.com Twitter: https://x.com/WTAFRich Substack: https://substack.com/@richardwillett   Please check out Sam Tripoli's internet: Linktree: https://linktr.ee/samtripoli Please Follow Sam Tripoli's Stand Up Youtube Page: https://www.youtube.com/@SamTripoliComedy Please Follow Sam Tripoli's Comedy Instagram:  https://www.instagram.com/samtripolicomedy/ Please Follow Sam Tripoli's Podcast Clip Instagram: https://www.instagram.com/samtripolispodcastclips/   Thank you to our sponsors:  True Werk: TRUEWERK is hell-bent on creating the most technical, high-performance workwear in the world. The TRUEWERK story begins in the Colorado mountains where a trade worker knew there had to be a better solution than the wet, heavy gear that was weighing him down.  Check out the full lineup and get 15 percent off your first order at TRUEWERK.com/tinfoil. Blue Chew: Make life easier by getting harder and discover your options at BlueChew.com! And we've got a special deal for our listeners: Try your first month of BlueChew FREE when you use promo code TINFOIL -- just pay $5 shipping. That's promo code TINFOIL. Visit BlueChew.com for more details and important safety information, and we thank BlueChew forsponsoring the podcast.    

My guest today is someone whose work has shaped the very code of modern biology, and whose vision continues to ripple across fields as vast as genomics, synthetic biology, age reversal, and artificial intelligence.Dr. George Church is a a true pioneer, Professor of Genetics at Harvard Medical School,a molecular engineer, chemist and serial entrepreneur as the co-founder of more than 50 biotech companies. He has helped invent many of the technologies that now define the genomic era, from CRISPR optimization to DNA data storage, and he was one of the first humans to ever publicly share his full genome and medical history.In this conversation, we explore the edge where science meets spirit.We talk about synthetic biology as a modern myth, DNA as a vessel of intelligence, and what it means to engineer life with intention. We dive into radical transparency, longevity research, AI collaboration, and the philosophical gravity of rewriting the arc of aging.This episode is not just about technology. It is about becoming.It is about asking: What does it mean to choose our evolution, consciously, ethically, and with awe.Episode highlights:00:04:30 – Sleep states and engineered serendipity: tapping creativity through unconscious rhythms00:06:30 – Synthetic biology as a modern myth: Promethean fire and the sacred aesthetic of science00:08:30 – DNA as memory, medium, and myth: encoding images in bacterial genomes00:10:00 – Is DNA a vessel of intelligence beyond biology?00:13:30 – Preserving culture in encoded DNA: who might decode it in the far future?00:16:00 – Are we alone in the universe? Dr. Church's speculative yet grounded view00:18:30 – What should we preserve for the next million years? The humility of legacy00:21:00 – DNA as sacred text: what it teaches us about identity, ancestry, and consciousness00:24:00 – Radical transparency: the Personal Genome Project and sharing his own genome00:29:00 – Rethinking consent, privacy, and research ethics in human genomics00:32:00 – From printing press to gene sequencers: the dawn of programmable biology00:33:30 – From slowing aging to redesigning it: reprogramming human cells and organs00:36:00 – How smarter gene, cell, and organ therapies could surpass pharmaceuticals00:40:00 – Personalized vs. generic medicine: the case for affordable global health00:43:30 – Aging as a treatable condition: tackling multiple pathways at once00:46:30 – Ethical and spiritual questions at the threshold of biological reinvention00:49:00 – The risks of artificial general intelligence vs. the promise of scientific AI00:52:30 – Why narrow scientific AI (like protein design) offers real-world breakthroughs00:54:30 – Will synthetic intelligence ever hold ethical responsibility?00:55:00 – Final reflections: safety, accessibility, and helping humanity fulfill its potentialResources mentioned:WebsitesWyss Institute: https://wyss.harvard.edu/team/core-faculty/george-church/Harvard Department of Genetics: https://icgd.bwh.harvard.edu/team/george-churchBiophysics at Harvard: https://biophysics.fas.harvard.edu/people/george-m-churchChurch Lab:

Robert explores Dr. Church's weird history with eugenics adjacent projects, like the world's creepiest dating app, and how Colossal Biosciences was created and immediately used by the Trump administration as an excuse to attack the Endangered Species Act.See omnystudio.com/listener for privacy information.

Robert walks Langston Kerman through the story of Dr. George Church, a very real scientist who co founded the company making bullshit claims of "de extincting" dire wolves. (2 Part Series) Sources: George Church, Colossal W*nker – For Better Science Can Gene Therapy Slow Ageing in Dogs? - Gowing Life Never-ageing Anti-aging to cure COVID-19 – For Better Science The original sins of Leonard Guarente – For Better Science Jeffrey Epstein Hoped to Seed Human Race With His DNA - The New York Times Biologist George Church apologizes for contacts with Jeffreyticl Epstein Genetics Company Wants To Bring Iconic Tasmanian Tiger Back From Extinction - Newsweek Gene editing company hopes to bring dodo ‘back to life’ | Extinct wildlife | The Guardian Jeffrey Epstein-Funded Geneticist Is Building a Dating App That Only a Eugenicist Could Love George Church Explains How DNA Will Be Construction Material of the Future - DER SPIEGEL Geneticist George Church gets funding for lab-grown woolly mammoths Wooly Mammoth De-extinction Scientist Reveals Plan To Create 'Arctic Elephant' - Newsweek Bringing back dinosaurs or making new ones? – DW – 06/10/2015 ‘If you’re not failing, you’re probably not trying as hard as you could be’ — Harvard Gazette CRISPR gene editing on human embryos may be dangerous Here are some actual facts about George Church’s DNA dating company | MIT Technology Review Scientist on the Loose: George Church Strays Into Eugenics—Again | Center for Genetics and Society So...What do we think of Colossal Biosciences? : r/pleistocene The "de-extinction" of the woolly mammoth, a "Colossal" hoax? - Genomic chronicles | Medicine/Science Hiltzik: New frontiers in pseudoscientific baloney - Los Angeles Times Colossal Liar Wolves – For Better Science Meet The Disruptors: How Ben Lamm & Hypergiant Are Shaking Up the Space and AI Industries | by Jason Hartman | Authority Magazine | Medium Millionaire Ben Lamm Warns Against Entrepreneurship - Great Entrepreneurs The Serial Entrepreneur Turned Billionaire: Ben Lamm’s Tech and Science Revolution | Where Business News Meets Thought Leadership How 39-year-old Ben Lamm has started five companies Meet Ben Lamm: The World's First De-extinction Billionaire - Forbes India Oral history interview with George M. Church - Science History Institute Digital Collections Dr. George Church, Founding Father of Genomics | News | W.I. The Church Of George Church The World Has a Data Storage Problem. Is DNA the Answer? - proto.life DNA: The Future of Data Storage?. DNA, with its amazing storage… | by Nithil Krishnaraj | TechTalkers | Medium See omnystudio.com/listener for privacy information.

Karl and Erum sit down with Daniel Goodwin, co-founding Director of Homeworld Collective alongside his friend and collaborator Paul Reginato. Together, they explore how to build resilient, values-aligned infrastructure for a flourishing bioeconomy—beyond the venture model.From climate biotech to systems thinking, Daniel shares how Homeworld Collective is more than just a network—it's an emergent, mycelial community focused on care, collaboration, and collective intelligence. The conversation weaves through everything from the limits of "techno-solutionism" to the power of story in science, and the need to design not just tools, but the conditions for innovation to thrive.If you're thinking about the future of biotech, and how culture, community, and infrastructure intersect to make it real—this episode is for you.Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing?Learn more at ⁠⁠⁠⁠⁠⁠⁠www.messaginglab.com/groweverything⁠⁠⁠⁠⁠⁠⁠ Chapters:00:00:00 – Welcome to the Biofuture: Erum and Karl kick things off in full grind mode.00:00:16 – Biotech Boom Times: Why the field never sleeps (and neither do the hosts).00:01:01 – Inside the AI Emergence Summit: Smell farms, AGI hype, and real talk on moats.00:03:21 – DIY Healthcare with AI: What happens when you feed your genome to a chatbot?00:05:35 – Can AI Decode Biology? Drug discovery and the limitations of human cognition.00:07:49 – Mammoths, Models & Media: Colossal Biosciences and the narrative power of science.00:11:32 – Meet Daniel Goodwin: Systems thinker, community builder, biotech whisperer.00:12:03 – On George Church: The unintentional influence that shaped Homeworld's DNA.00:18:07 – What Is Homeworld Collective? Building more than a Slack—building a system.00:20:47 – Imagining the Next Bio Era: Biotech's renaissance as culture, not just tech.00:26:52 – Idea Porn & Biotech Fiction: When storytelling shapes science (and vice versa).00:29:54 – Collaborating with Biology: Designing with, not against, nature's blueprint.00:30:07 – Rivers as Systems: What infrastructure can learn from ecosystems.00:30:54 – Biomanufacturing Is Hard: Real talk on what it takes to scale with biology.00:32:08 – Carbon Capture, Naturally: Biodesign, fermentation, and the future of CO₂.00:33:45 – Biosecurity + Ethics: Guardrails, governance, and growing with intention.00:41:18 – Prototype Like a Scientist: What biotech can borrow from product design.00:49:07 – Cleaning Up Chemistry: Synbio's role in reshaping industrial pollution.00:52:46 – Looking Ahead: Final reflections, future infrastructure, and quiet revolutions.Links and Resources:Homeworld CollectiveThe Climate Biotech PodcastKarl and Erum on the Climate Biotech PodcastAI Circle Osmo.AIDoctors Told Him He Was Going to Die. Then A.I. Saved His Life.Colossal BiosciencesHoping to revive mammoths, scientists create 'woolly mice'George Church episode, interviewed by Homeworld CollectiveNeuroscience Needs Hackers, Scientific American Liquid Trees A Natural History of the Future: What the Laws of Biology Tell Us about the Destiny of the Human Species by Robb DunnTopics Covered: climate biotech, George Church, Churchian Juxtaposition, idea porn, genetic engineering, geo biotech, environmental engineering, Have a question or comment? Message us here:Text or Call (804) 505-5553 ⁠⁠⁠⁠⁠⁠⁠Instagram⁠⁠⁠⁠⁠⁠⁠  / ⁠⁠⁠⁠⁠⁠⁠Twitter⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠LinkedIn⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠Youtube⁠⁠⁠⁠⁠⁠⁠ / ⁠⁠⁠⁠⁠⁠⁠Grow Everything⁠⁠⁠⁠⁠Email: groweverything@messaginglab.comMusic by: Nihilore

Ein Start-up plant für 2028 die Geburt eines Mammuts. Zuletzt hat die Firma immerhin flauschige Mäuse erschaffen. Wer steckt hinter der Idee und was kann daraus werden? SPIEGEL-Redakteur Johann Grolle ordnet den Plan ein. Sagt uns, wie euch Shortcut gefällt. Hier geht's zur Umfrage. »SPIEGEL Shortcut« – Schneller mehr verstehen. Wir erklären euch jeden Tag ein wichtiges Thema – kurz und verständlich. Für alle, die informiert mitreden wollen. Neue Folgen von Shortcut gibt es von Montag bis Freitag auf Spiegel.de, YouTube und überall, wo es Podcasts gibt. Links zur Folge: Sind diese Mäuse ein erster Schritt zum Comeback der Mammuts? Forscher finden fast vollständig erhaltenes Mammutbaby Flauschig, scheu – und vom Aussterben bedroht ► Host: Maximilian Sepp ► Redaktion: Ilyass Alaoui, Florian Hofmann ► Redaktionelle Leitung: Jannis Schakarian, Marius Mestermann ► Produktion: Christian Weber ► Postproduktion: Florian Hofmann, Christian Weber ► Musik: Above Zero ►►► Lob, Kritik, Themenvorschläge? Schreibt uns: hallo.shortcut@spiegel.de +++ Alle Infos zu unseren Werbepartnern finden Sie hier. Die SPIEGEL-Gruppe ist nicht für den Inhalt dieser Seite verantwortlich. +++ Den SPIEGEL-WhatsApp-Kanal finden Sie hier. Alle SPIEGEL Podcasts finden Sie hier. Mehr Hintergründe zum Thema erhalten Sie mit SPIEGEL+. Entdecken Sie die digitale Welt des SPIEGEL, unter spiegel.de/abonnieren finden Sie das passende Angebot. Informationen zu unserer Datenschutzerklärung.

We're taking you through the looking glass to explore 'mirror life': could we be about to flip biology on its head? Like this podcast? Please help us by supporting the Naked Scientists

In this special Grow Everything episode swap with The Climate Biotech Podcast, Erum and Karl introduce a mind-blowing conversation with the one and only George Church. If you're into synthetic biology, you already know he's a legend—co-founding 50+ biotech companies and pushing the boundaries of what's possible with DNA. In this episode, George talks about scaling microscopic innovations to solve massive global challenges—think rewilding ecosystems, bio-mining for new molecular tools, and engineering biology to fight climate change. He even throws out wild ideas like testing space colonies on Earth before heading to Mars. Stick around after the episode for Erum and Karl's takeaways and a heads-up on a funding opportunity from Homeworld Collective! Grow Everything brings the bioeconomy to life. Hosts Karl Schmieder and Erum Azeez Khan share stories and interview the leaders and influencers changing the world by growing everything. Biology is the oldest technology. And it can be engineered. What are we growing? Learn more at ⁠www.messaginglab.com/groweverything⁠  Chapters: 00:00:00 – Microscopic, but make it massive 00:00:17 – Erum and Karl are back—let's grow everything 00:00:36 – The Homeworld Collective: where biotech meets climate 00:01:44 – Enter George Church (yes, that George Church) 00:03:34 – From river dolphins to rewriting life—George's early days 00:05:25 – Synthetic biology's glow-up (and growing pains) 00:07:18 – Climate biotech: hurdles, hype, and huge potential 00:11:32 – Can biotech be infinitely scalable and atomically precise? 00:21:36 – Inorganic synthetic biology: when life meets metal 00:24:50 – Biotech's biggest climate bets—what's next? 00:27:02 – Genetic engineering, but make it ecosystem-sized 00:29:04 – Space colonies on Earth? Let's test before Mars 00:37:26 – Rapid-fire Q&A—George Church vs. the audience 00:39:49 – Curiosity is the best lab equipment—George's advice 00:42:26 – Final thoughts from Karl and Erum, next steps, and a funding opportunity Links and Resources: The Climate Biotech Podcast Homeworld Collective Garden Grants: Biotech in Greenhouse Gas Removal Colossal Biosciences Topics Covered:  Genetic engineering, biotech, bioeconomy, research and development, climate biotechnology Have a question or comment? Message us here: Text or Call (804) 505-5553  ⁠Instagram⁠  / ⁠Twitter⁠ / ⁠LinkedIn⁠ / ⁠Youtube⁠ / ⁠Grow Everything⁠ Email: groweverything@messaginglab.com Music by: Nihilore Production by: Amplafy Media

(00:00) Introduction (02:27) Petrie-Flom Center Open House – Health Law, Biotechnology, and the Future (51:55) Q&A --- Support this podcast: https://podcasters.spotify.com/pod/show/theunadulteratedintellect/support

Adam Marblestone is the CEO of Convergent Research. He is working with a large and growing network of collaborators and advisors to develop a strategic roadmap for future FROs. Outside of CR, he serves on the boards of several non-profits pursuing new methods of funding and organizing scientific research including Norn Group and New Science, and as an interviewer for the Hertz Foundation. Previously, he was a Schmidt Futures Innovation Fellow, a Fellow with the Federation of American Scientists (FAS), a research scientist at Google DeepMind, Chief Strategy Officer of the brain-computer interface company Kernel, a research scientist at MIT, a PhD student in biophysics with George Church and colleagues at Harvard, and a theoretical physics student at Yale. He has also previously helped to start companies like BioBright, and advised foundations such as Open Philanthropy.Session SummaryIn this episode of the Existential Hope Podcast, our guest is Adam Marblestone, CEO of Convergent Research. Adam shares his journey from working on nanotechnology and neuroscience to pioneering a bold new model for scientific work and funding: Focused Research Organizations (FROs). These nonprofit, deep-tech startups are designed to fill critical gaps in science by building the infrastructure needed to accelerate discovery. Tune in to hear how FROs are unlocking innovation, tackling bottlenecks across fields, and inspiring a new approach to advancing humanity's understanding of the world.Full transcript, list of resources, and art piece: https://www.existentialhope.com/podcastsExistential Hope was created to collect positive and possible scenarios for the future so that we can have more people commit to creating a brighter future, and to begin mapping out the main developments and challenges that need to be navigated to reach it. Existential Hope is a Foresight Institute project.Hosted by Allison Duettmann and Beatrice ErkersFollow Us: Twitter | Facebook | LinkedIn | Existential Hope InstagramExplore every word spoken on this podcast through Fathom.fm. Hosted on Acast. See acast.com/privacy for more information.

Aging (Aging-US) was a proud sponsor of the “Future of Aging Research Mixer 2024” hosted by the Aging Initiative at Harvard University on November 15 in Boston. This event united a vibrant community of students, researchers and technologists, all driven by a shared mission: advancing innovations in aging research and longevity science. Key Highlights from the Future of Aging Research Mixer 2024 The event kicked off with inspiring opening remarks and a keynote by George Church, professor at Harvard Medical School, founding member of the Wyss Institute, and co-founder of over 50 biotech companies. He was joined by Kat Kajderowicz, an MIT PhD student and Principal at age1. Together, they highlighted the interdisciplinary nature of aging research and its immense potential to drive transformative advancements. Jesse Poganik, HMS Instructor in Medicine and Executive Co-Director of the Biomarkers of Aging Consortium, discussed the evolution of aging science and the critical role biomarkers play in understanding aging processes and assessing the effectiveness of interventions aimed at slowing or reversing age-related changes. Alex Colville, co-founder and general partner at age1, explained how venture capital can accelerate innovation in longevity biotechnology. He shared career advice for aspiring researchers and paid tribute to his mentor, Dr. David Sinclair, a pioneer in aging research. These talks highlighted the importance of mentorship, interdisciplinary collaboration, and investment in driving progress in the aging research field. Read the full summary - https://aging-us.org/2024/11/agings-commitment-to-advancing-research-sponsoring-the-future-of-aging-research-mixer/ About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

What is de-extinction? The process of de-extinction is all about bringing extinct species back to life. It became known in the 2010s, thanks to an ambitious plan from American geneticist George Church, who dreamed of resurrecting the woolly mammoth, an animal which has been extinct for 3700 years. Fast forward to the 2020s and Church's bioscience startup Colossal is now eding closer towards making that a reality. As of March 2022, Colossal announced that it had raised a total of $75M for the project. Is it really possible to revive extinct animal species? Why would we want to bring extinct species back to life? How is the idea of de-extinction being received by the scientific community? In under 3 minutes, we answer your questions! To listen to the last episodes, you can click here: What are happy hormones? What is erectile dysfunction? Who are Arcade Fire? A podcast written and realised by Joseph Chance. First broadcast: 10/05/2022 Learn more about your ad choices. Visit megaphone.fm/adchoices

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Senseonics has received FDA clearance for a one-year continuous glucose monitoring system. The company's commercial partner, Ascensia, is in talks with insulin pump manufacturers to create an automated insulin delivery system. Zimmer is pulling its hip implant off the market due to fracture risk, Bausch + Lomb is considering a sale, and Masimo investor claims a proxy war win as CEO Joe Kiani fails to retain a board seat. The wearables market is expected to see significant growth, with adhesives playing a vital role in development. Other noteworthy stories include DermaSensor's skin cancer detection device, a Senate committee holding Steward CEO in contempt, and Medtronic detailing a study of adaptive neurostimulation in Parkinson's disease.Brisk Iced Tea brought back its classic claymation ad campaign featuring Doja Cat to target Gen Z. E.l.f. launched a skincare campaign with "Sinfluencer" Megan Stalter. Pizza Hut put resumes on boxes to help job seekers stand out. Frito-Lay used burner phones in a campaign targeting Gen Z for Flamin' Hot Cheetos. Chipotle planned a digital scavenger hunt to give out $1 million in free quesadillas. Customers' trust in AI is low, impacting purchasing decisions.Cigna is scaling back its Medicare Advantage footprint in 8 states next year, affecting roughly 5,400 members, mostly in Florida. Johnson & Johnson is facing sanctions over a plan to rebate 340B drugs, while Express Scripts is suing the FTC over a report criticizing pharmacy benefit managers. The US is behind other wealthy nations in healthcare despite spending the most, with a Commonwealth Fund analysis ranking the US last in access to care and health outcomes.Cigna is reducing its Medicare Advantage footprint in 8 states, affecting around 5,400 members, mainly in Florida. CarePoint Health may lay off 2,600 employees due to financial struggles. The House committee passed a bill to extend telehealth flexibilities in Medicare for another two years. Steward Health Care auctioned assets, with Christus Health set to purchase a Texas-based medical center for $4.5 million.MilliporeSigma is partnering with an experienced viral vector CDMO to offer solutions for the production of cell and gene therapies. They invite attendees of the Mesa conference in Phoenix to visit their booth or schedule a meeting to learn about their viral vector development and manufacturing capabilities.The Senate has voted to hold Steward CEO in contempt for defying a congressional subpoena. The US healthcare system lags behind other wealthy nations in performance despite spending the most. Oak Street Health pays $60 million to settle allegations of a kickback scheme, and J&J faces sanctions over a plan to rebate 340B drugs.Medtech news from September 19, 2024, includes updates on various companies and developments in the industry. Masimo's proxy fight is coming to an end, with a shareholder vote looming. Axonics wins a patent dispute against Medtronic, while Boston Scientific's proposal to buy Axonics is still under review.A startup from George Church's lab has raised $75 million to develop 'supercell' medicines, claiming it can create off-the-shelf therapies from induced pluripotent stem cells faster and simpler than current methods. Roche's Xofluza has shown promising results in reducing flu transmission in a phase 3 study, marking the first time an antiviral drug has achieved this in a global trial.The text discusses the latest advances in oncology research presented at the ESMO conference, focusing on the challenges faced by the pharmaceutical industry in expanding patient access and improving cancer research outcomes.The text promotes a webinar by QT Group on September 26th focusing on continuous compliance for medical software, specifically addressing how to maintain software quality and compliance with medical standa

“My long-term goal is to model the pathways involved in human aging in order to develop therapeutic interventions. I organize an annual aging conference in the Midwestern United States with the dual goal of promoting the aging as an adaptation theory and promoting the aging as a disease mindset. The conference website is curing-aging.com.” Check out these other great views as well:Interview with Aubrey De Grey: https://youtu.be/DHvoPlcWwg4Interview with George Church: https://youtu.be/yNplpykf0B4Interview with Lisa Fabiny-Kiser: https://youtu.be/bE5jEGE5-OMInterview with Matt Kaeberlein: https://youtu.be/9QJ_ak3a05QInterview with Nir Barzilai : https://youtu.be/LuOAShcjOt0Interview with Michael Levin : https://youtu.be/5XvDdbYzwf8. PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com David Katz linkshttps://www.linkedin.com/in/davidwarrenkatz/https://www.youtube.com/watch?v=zhbOo_INMwg&t=65s&ab_channel=CuringAginghttps://www.curing-aging.com/ Timestamps00:00 start00:20 Programed aging hypothesis explained01:20 Michael Levin / bioelectricity02:15 Telomerase / concerns around copies of copies04:15 Ability for immortality in animals04:44 Immortal jellyfish06:02 Butterfly brains06:40 Programmed aging in practice for therapies07:16 FDA aging as a disease08:33 Curing aging objectionable09:15 We need to work against our bodies10:18 Fasting / Michael Rae / Caloric restriction11:55 Highly against Richard Dawkins selfish gene and ideas around evolution13:20 Start of slides13:50 Why do we age / David's argument18:20 Different types of aging23:20 Induce damage to test hypothesis25:10 David St Clair work26:20 Evolution has consistently selected for aging29:20 Aging and cancer30:00 exponential population growth31:00 Evolution as an ecological thing32:00 Animals getting bigger and smaller on small island / evolution as multivariable equation35:11 Mole Rats and rats36:25 people who get castrated live longer37:22 Bryan Johnson / interfering with body38:00 Testosterone / women live longer39:22 Mechanism of the body working against itself40:15 Easy interventions / keeping track of time for puberty, death, etc44:30 Squirrels having a year long internal clock46:00 Uniform life events / aging clock / evidence that convinces people50:50 ATF4 Pathway / muscle mass52:00 Not even trying to make therapies ATF454:40 Developing therapies against the body55:30 VCs at conference56:10 Exploring this hypothesis58:40 Tricking body to “think” it's younger59:10 Aubrey De Grey like hallmarks of aging clock1:00:00 Epigenetic clocks / biologic clocks01:01:30 Disrupting dreams / sleep01:02:50 Sleep affecting aging01:04:08 People who stop sleeping die within a number of weeks01:04:40 Does the biological clock have state and turning it back01:10:20 Steel man argument against the Programed aging hypothesis01:10:55 A good case for the clock / time of day, year, and stage of year01:13:00 Dolphins and sleep01:13:30 Target therapy with this theory01:15:40 Children's hospital01:16:05 Kids better able to fight off cancer / medicine divided01:17:11 PhD Tensor decomposition presentation / fundamental relationship of matrices01:18:40 implications and pushback for the tensor decomposition01:19:30 What are the trade offs / stop measuring algorithms based off complexity01:21:18 Real life example / chromosomes01:24:30 SENS and the human genome li...

Dr. Peter Lidsky posits that aging is not merely a process of accumulating damages, as commonly believed, but rather a programmed adaptation akin to a part of the immune system. His hypothesis suggests that aging evolved to eliminate older individuals who might be susceptible to severe chronic diseases. Check out these other great views as well:Interview with Aubrey De Grey: https://youtu.be/DHvoPlcWwg4Interview with George Church: https://youtu.be/yNplpykf0B4Interview with Lisa Fabiny-Kiser: https://youtu.be/bE5jEGE5-OMInterview with Matt Kaeberlein: https://youtu.be/9QJ_ak3a05QInterview with Nir Barzilai : https://youtu.be/LuOAShcjOt0Interview with Michael Levin : https://youtu.be/5XvDdbYzwf8 About the showThe Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. Learning with lowell linksYoutube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips:https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com/ Peter Lidsky linkshttps://twitter.com/LidskyPeterhttps://www.linkedin.com/in/peter-lidsky-71997540 Timestamps00:00 Start00:10 who is Peter Lidsky / research / longevity01:30 Academia differences04:20 Aging explained and the Squirrel test07:20 Pathogen control hypothesis15:50 Lifespans different organisms (fanq)17:55 Natural experiments to prove/disprove (fanq)24:30 Implications of Theory of aging25:00 Senescent cells31:32 Therapeutics / interventions from his research33:00 Implications of his theory37:50 Limits of aging40:10 What do people need to see to believe his theory44:30 Show him the drug that is better than rapamycin46:40 Data sharing / organization to push forward48:50 What is slowing aging research49:50 Pleiotropic genes / aging52:00 Research at Hong Kong52:40 Focus of future research53:55 Devices for research56:00 Bryan Johnson Blueprint59:20 People to follow01:00:00 place to stay up to date01:01:30 Thanks for all the fish longevity #aging #agingresearch

Kim takes you to the next level of health and performance without the standard prescription of hours of cardio or chicken and broccoli.With laser focus on what has been proven to work for improved performance, sleep, cognitive function, metabolic health and stress levels, you will get maximum results with minimum effort. Work smarter, not harder to make your body look and perform the way you intend it to.The Fabulous in 15 approach is a minimalist protocol that takes you from stressed and tired to vibrant and energetic in the shortest possible amount of time. Check out these other great views as well:Interview with Aubrey De Grey: https://youtu.be/DHvoPlcWwg4Interview with George Church: https://youtu.be/yNplpykf0B4Interview with Lisa Fabiny-Kiser: https://youtu.be/bE5jEGE5-OMInterview with Matt Kaeberlein: https://youtu.be/9QJ_ak3a05QInterview with Nir Barzilai : https://youtu.be/LuOAShcjOt0Interview with Michael Levin : https://youtu.be/5XvDdbYzwf8. PODCAST INFO:The Learning With Lowell show is a series for the everyday mammal. In this show we'll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn't normally ever get to hear. The Host of the show – Lowell Thompson- is a lifelong autodidact, serial problem solver, and founder of startups. LINKSSpotify: https://open.spotify.com/show/66eFLHQclKe5p3bMXsCTRHRSS: https://www.learningwithlowell.com/feed/podcast/Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-QYoutube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfAWebsite: https://www.learningwithlowell.com Kim rahir linkshttps://kimrahir.com/https://www.linkedin.com/in/kim-rahir/?originalSubdomain=eshttps://www.instagram.com/kim.rahir/?hl=en Timestamps / chapters00:00 Start00:05 Kim Rahir00:50 Accomplishments after MS diagnosis / Olympic weight lifting02:04 Olympic weight lifting03:00 Deadlift04:30 Powerlifting07:55 Mike Tyson, Adversity and training10:10 Rejuvenating after training13:00 Getting through lack of motivations / 5 minute rule16:55 Only 5 minutes19:15 Lifelong learning24:20 Wheelchair to power lifting29:40 MS32:55 202434:55 Dream number36:55 Meditation / mindfulness39:00 Learn mediation / headspace41:45 Strength training43:40 Weeks until getting better45:55 Train to failure48:00 Health and energy focused49:30 Time intensity52:40 Diet / food!54:55 Family dinners and not over eating57:55 Celebrities / interesting meals01:01:45 Community01:05:10 Saying what you want01:08:55 how to get family on board01:11:30 Women vs men advantages and disadvantages01:13:10 Adversity01:14:30 Self Advocacy / MS diagnosis01:22:00 Post having kids01:23:55 One thing you can do right now01:24:55 Her Clients01:25:40 Thank you for all the fish weightlifting #multiplesclerosis #olympicweightlifting

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.Mountain Dew introduced the Mountain Dude character in a new campaign called "Do the Dew" created by Goodby Silverstein & Partners. The campaign features a stylish brand character and encourages consumers to get active. Amazon released a back-to-school ad promoting savings, Heinz launched a campaign inspired by superheroes for their condiments, and Kraft Heinz named former Pepsi marketer Todd Kaplan as their North America CMO. Hershey also handed US media duties to Publicis. Industries are adopting the media network model to replicate the success of companies like Amazon and Walmart. Additionally, America's most trusted brands like Nvidia, Sony, and Adidas are discussed in a sponsored content piece. Other trending topics include Havas agencies losing B Corp status, Google accused of misleading consumers, the WNBA securing lucrative media rights deals, and Meta in talks to buy a stake in eyewear giant EssilorLuxottica.Transitioning to the world of biotech, Revolution Medicines is advancing its cancer drug, a ras inhibitor, to phase 3 trials after demonstrating tumor reduction in pancreatic cancer patients. The drug showed promising results but also had high rates of side effects like rash and nausea. Roche's obesity pill showed significant weight loss in a small study, while Gilead's Chief Medical Officer is set to depart next year. The biotech industry in 2024 is seeing progress in gene editing, mRNA, and cell therapies, offering optimism for the future of medicine. Caribou is cutting its workforce, Sionna is exploring abandoned cystic fibrosis drugs from AbbVie, and the industry is focusing on successful commercialization strategies. Overall, the industry is evolving with new treatments and developments shaping the landscape of biotech and pharma.Shifting gears to healthcare news, the House Committee has urged the FDA to suspend the lab-developed test rule, citing concerns about potential alterations to the United States' laboratory testing infrastructure. Steward executives received significant compensation before the company declared bankruptcy, and UnitedHealth's cyberattack response costs are expected to exceed $2.3 billion this year. Senators have introduced bipartisan healthcare cybersecurity legislation, while a Chicago children's hospital faces class action lawsuits after a cyberattack. Branded calling is highlighted as a way to increase patient answer rates, and AI is showcased as a tool to address healthcare challenges. Overall, the healthcare industry is facing various challenges related to cybersecurity, financial pressures, and patient care.In the realm of pharmaceuticals, Boehringer Ingelheim has partnered with GoodRx to offer its Humira biosimilar at a 92% discount. This move is aimed at capitalizing on Humira's decreasing market share. Artiva Biotherapeutics has announced an upsized IPO of $167 million to support the development of its therapy for systemic lupus erythematosus. George Church's startup has raised $60 million for its investigational therapy for gout, while Aveo's Fotivda combination therapy did not meet its primary efficacy endpoint in a phase III study. Invitro Cell Research is also working on preventive and regenerative medicine to help people live healthier lives. Other news includes the FDA rejecting Orexo's opioid overdose drug and granting a third indication for Phathom's Voquezna. Pfizer's once-daily weight loss pill and ongoing disputes over CRISPR patents are also highlighted.That's all for today's episode of Pharma and Biotech daily. Stay informed and have a great day!

Hi Friends,   It's Nina's Note #80!In honor of this milestone, I have something new for you today, a debut interview for the Nina's Notes Podcast. On this inaugural episode, I am thrilled to welcome Michael Geer, a visionary determined to redefine our approach to aging.

George Church, professor of genetics at Harvard Medical School, leads a large research group at the Wyss Institute for Biologically Inspired Engineering. A pioneer in the fields of personalized genomics and synthetic biology, he has co-founded over 50 biotech companies. In 2017, Time magazine named him one of the 100 most influential people in the world. In this conversation, we discuss the importance of embracing outliers and taking calculated risks – it's not about never failing, it's about failing a million times a day. As Yogi Berra said, "When you come to a fork in the road, take it!”  George argues that you can change the world as long as you don't care who gets the credit. He recommends shooting for the stars – maybe you'll hit the moon. This episode was supported by Research Theory (researchtheory.org). For more information on Night Science, visit https://www.biomedcentral.com/collections/night-science .

In this episode, we are excited to welcome George Church, Professor at Harvard Medical School and MIT, and Co-founder of Eugit Therapeutics, Colossal Biosciences, Arrived AI, and eGenesis. He is also the Director of PersonalGenomes.org, the world's only open-access information hub for human genomic, environmental, and trait data, as well as an IARPA BRAIN Project and the NIH Center for Excellence in Genomic Science. If that weren't enough, George was named one of the 100 most influential people in the world in Time Magazine's 2017 Time 100 list. In 2022, he was featured among the most influential people in biopharma by FiercePharma, where he was listed among the top 8 most famous geneticists in human history. All to say, you won't want to miss this episode with a genetics superstar!

On this episode of FYI, ARK Multiomics analyst Nemo Marjanovic sits down with Professor George Church, a renowned geneticist and entrepreneur from Harvard. They discuss the evolution of genomic sequencing technologies, the intersection of genomics and blockchain for privacy, and the fascinating potential of DNA for data storage. They delve into multiomic approaches for enhanced biological understanding, the transformative impact of artificial intelligence (AI) in medical advancements, and George's groundbreaking research on aging. Key Points From This Episode:Evolution of genomic sequencing: from short to long readsBalancing privacy with blockchain in genomicsThe potential of DNA as a universal data storage mediumAdvancements and challenges in writing DNA for data encodingThe growing importance and integration of multiomic approachesHow AI and high-throughput screening revolutionize drug discoveryInsights into startups from George's lab leveraging machine learning and multiomicsRevolutionary research on aging: targeting multiple pathways simultaneouslyThe concept of protective gene therapies against all virusesEmerging technologies in genome synthesis and developmental biology

In this episode of For Your Innovation, Ali Urman chats with Ben Lamm, CEO of Colossal, about the groundbreaking venture aimed at resurrecting extinct species, starting with the woolly mammoth. Lamm shares insights into his journey from tech to biotech, highlighting the fusion of artificial intelligence (AI), automation, and genetic editing to challenge the boundaries of science and conservation. He delves into the ecological and scientific ramifications of bringing back extinct species and addresses the technological, regulatory, and ethical challenges faced along the way. Join us as we explore how Colossal is not just redefining de-extinction but also contributing significantly to conservation efforts and genetic research."I don't have a background in biology. My background is in finance and accounting. And then I've always been passionate about starting businesses. And I've always just been massively curious. And it's funny, my massive curiosity kind of led me to the mammoth" -@federallammKey Points From This Episode:Ben Lamm discusses transitioning from tech entrepreneurship to biotech with ColossalColossal aims to bring the woolly mammoth back from extinction, inspired by George ChurchConvergence of AI, automation, and biotech in de-extinction and conservation effortsFormBio: A spin-off providing AI tools for cell and gene therapy, aiding in biotech researchThe role of computational biology and gene editing in reconstructing extinct speciesThe potential ecological benefits of reintroducing extinct species like the woolly mammothColossal's involvement in conservation efforts and genetic rescue, beyond de-extinctionChallenges and advancements in xenotransplantation and disease resistance in wildlifeRegulatory considerations for biotech innovations in de-extinction and gene editingLamm's admiration for innovative minds like George Church, breaking barriers in science

Bienvenue à ce nouvel épisode d'Au-delà de la thèse avec Papa PhD en collaboration avec la bourse Pre-Amp d'Amplitude Ventures !Cette semaine, je parle avec Michael Mee et Virginie Petel-Légaré de la bourse Pre-Amp, un programme d'été qui transporte les jeunes scientifiques ua doctorat dans l'univers de la création d'entreprises et du capital de risque. Michael Mee est directeur chez Amplitude Ventures, le principal fonds de capital-risque du Canada dans le domaine de la biotechnologie et de la santé. Après avoir obtenu son doctorat en ingénierie biomédicale dans le laboratoire de George Church à HMS, Michael a travaillé chez Flagship Pioneering dans le domaine de la création d'entreprises. Chez Flagship, il s'est concentré sur le développement de deux entreprises de microbiome dans les domaines agricole (Indigo) et thérapeutique (Kaleido), sur la cofondation et le lancement d'une nouvelle plateforme thérapeutique et d'une entreprise de thérapie génique (Cobalt Biomedicine/Sana Therapeutics) et, plus récemment, sur le développement de nouvelles entreprises dans les domaines de la mise au point de médicaments basés sur l'IA et de l'édition de gènes. L'un de ses objectifs à long terme a toujours été de ramener chez lui les enseignements tirés de Boston afin de contribuer à l'écosystème biotechnologique canadien. À cette fin, il a récemment déménagé à Montréal et se réjouit de pouvoir atteindre cet objectif avec l'équipe grandissante d'Amplitude et de Pre-Amp.Virginie Petel-Légaré est actuellement Venture Associate chez Pre-Amp. Elle a fait partie de la première cohorte de la bourse Pre-Amp en 2021 et travaille avec Amplitude depuis, d'abord en tant que consultante, puis en tant qu'employée à temps plein. Virginie a terminé son baccalauréat en physiologie à l'Université McGill et a décidé de se concentrer sur les neurosciences. Elle a obtenu une maîtrise en neurosciences de l'Université de Montréal, où elle a étudié les déficits de la mémoire de travail en relation avec les modifications anatomiques de la connectivité pariéto-frontale. Virginie a terminé son doctorat à l'Institut neurologique de Montréal (Université McGill) en se concentrant sur le rôle du dysfonctionnement mitochondrial dans la SLA et la maladie de Parkinson. Ce que tu apprendras dans cette entrevue : Comment la bourse Pre-Amp se distingue par son focus sur l'apprentissage par l'expérience tout et comment elle offre un tremplin vers des carrières diversifiées hors de l'universitéComment le fait de travailler sur des projets hors de ton champ de compétence habituel peut débloquer ta créativité et contribuer à l'innovation.Comment tes compétences académiques peuvent être transférables et précieuses dans le secteur entrepreneurial.Et bien plus.Bonne écoute !La bourse Pre-Amp t'intéresse ? Envoie ton CV et ta lettre de motivation à > cette adresse courriel < - tu as jusqu'au 31 mars 2024 pour postuler ! Les ressources de cet épisode : Bourse Pre-Amp | Page WebAmplitude Ventures | Site Web Tu aimeras aussi ces épisodes : Marie Itoiz – Se préparer à l'après-doctorat : PapaPhD.com/marie-itoiz-adtAlexandre Bran - Le doctorat, une expérience transformatrice : PapaPhD.com/260Rémi Quirion – Projeter les jeunes chercheur.e.s dans des carrières d'avenir : PapaPhD.com/203Nathalie Ouellette – L'astrophysique à la portée de tous : PapaPhD.com/nathalie-ouellette/

We're live with Deacon Terry Bellon, Deacon at St. George Church in Baton Rouge talks about why men should attend a Catholic retreat. Alan Migliorato, co-author of Failing Forward: Leadership Lessons for Catholic Teens Today joins us and Jordan and Lisa Tabor, Catholic business people and founders of Rain Will Bring Flowers Foundation, talk about the event Planting Seeds of Hope focusing on suicide prevention.

At the beginning of the year, the company behind the public effort to de-extinct the wooly mammoth announced it will also be de-extincting the dodo. The announcement stirred up a lot of excitement and questions about whether we can – or should – bring back species once they're gone. So this hour we're talking about de-extinction! We'll hear about what it takes to bring back extinct animals, efforts to build a safety net for plants that might go extinct in the future, and walk through some fun de-extinction thought experiments. GUESTS: Helen Pilcher: Science and comedy writer with a PhD in cell biology who wrote Bring Back the King: The New Science of De-extinction Ben Lamm: CEO of the de-extinction company Colossal, which he co-founded with George Church. Carlos de la Rosa: President and CEO of the Center for Plant Conservation Join the conversation on Facebook and Twitter. The Colin McEnroe Show is available as a podcast on Apple Podcasts, Spotify, Google Podcasts, Stitcher, or wherever you get your podcasts. Subscribe and never miss an episode! Subscribe to The Noseletter, an email compendium of merriment, secrets, and ancient wisdom brought to you by The Colin McEnroe Show. Colin McEnroe and Cat Pastor contributed to this show, which originally aired on May 18, 2023.Support the show: http://www.wnpr.org/donateSee omnystudio.com/listener for privacy information.

In this episode, vanguard geneticist Dr. George Church recounts his storied career from his early fascination with computers and science to his pioneering work in genomics and synthetic biology. Dr. Church developed innovative DNA sequencing methods that enabled the first sequencing of the human genome. He was also instrumental in developing CRISPR gene editing technology. Dr. Church discusses his controversial ideas around resurrecting wooly mammoths and using genome sequencing in dating apps to prevent genetic diseases. He also provides insights into founding genomics companies and the role of AI in advancing biotechnology. As a professor of genetics at Harvard Medical School and the founder of multiple genomics companies, Dr. Church emphasizes the potential for synthetic biology and genetics to transform medicine and society. Transcript.

Jason and Peter heard that a biotech company claimed that the long-deceased woolly mammoth will be brought back from extinction by 2027…Really, no really! Are we on the cusp of a real-life Jurassic Park? With new technology available to de-extinct long dead animals, potentially change the genetic code of human babies and the possibility of creating synthetic life, we needed to get some clarity. We had to find and talk to the man leading the science…and that man is Dr. George Church, known as the "father of synthetic biology. He is the Professor of Genetics at Harvard Medical School and Professor of Health Sciences & Technology at Harvard and MIT. In 2021 Dr. Church and entrepreneur Ben Lamm founded Colossal Biosciences, a synthetic biology company tasked in part with sequencing the remains of woolly mammoths which would allow them, in theory to “de-extinct” the ancient creatures.   In this episode: How do you de-extinct a woolly mammoth? The dangers lurking beneath melting permafrost. Redefining death. Creating human organs inside pigs. Bringing back those cryogenically frozen. Cold resistant Asian Elephants. Cultured meat and mammoth meatballs The dodo & Tasmanian tiger are coming back too?     Follow Dr. Church: X (Twitter): @GeoChurch   Follow us: www.reallynoreally.com Instagram YouTube TikTok Facebook Threads X (Twitter)See omnystudio.com/listener for privacy information.

What if you could bring back an animal that's gone extinct? Well, that's exactly what scientists are doing at Colossal Biosciences. On this episode of Little Curiosities, I sit down with Colossal CEO and Founder Ben Lamm and Head of Biological Sciences Eriona Hysolli, Ph.D. and hear about animals they are bringing back, where they plan to release them, and so much more. Let's talk about it shall we? ~~ Follow Kendall Long on Instagram: @itskendalllong Tik Tok: @itskendalllong ~~ ABOUT COLOSSAL BIOSCIENCES Colossal Biosciences was founded by emerging technology and software entrepreneur Ben Lamm and world-renowned geneticist and serial biotech entrepreneur George Church, Ph.D., and is the first to apply CRISPR technology for the purposes of species de-extinction. Colossal creates innovative technologies for species restoration, critically endangered species protection and the repopulation of critical ecosystems that support the continuation of life on Earth. Colossal is accepting humanity's duty to restore Earth to a healthier state, while also solving for the future economies and biological necessities of the human condition through cutting-edge science and technologies. To follow along, please visit: https://colossal.com/. ~~ COLOSSAL WEBSITE & SOCIALS Website: https://colossal.com Twitter/X: https://twitter.com/itiscolossal Instagram: https://www.instagram.com/itiscolossal/ LinkedIn: https://www.linkedin.com/company/itiscolossal/ Facebook: https://www.facebook.com/itiscolossal YouTube: https://www.youtube.com/@itiscolossal ~~ Little Curiosities With Kendall Long is brought to you by QCODE. To advertise on the show, contact us! Learn more about your ad choices. Visit megaphone.fm/adchoices

We've come a long way since DNA was first discovered in the mid 19th century. Today's scientists are using powerful engineering techniques to edit genes in human eggs and sperm, curing diseases and repairing defective genes before a child is even born. Some scientists are excited about these therapies, championing them as an exciting opportunity to create immunity to viruses, eliminate serious illnesses like AIDS, Alzheimer's, and cancer, and possibly reverse aging. Like prior innovations in medicine and technology, why wouldn't we embrace a science that allows people to live longer, healthier, and happier lives? Others are alarmed. They are worried that these new techniques raise a host of profound ethical issues. While eliminating genetic diseases is a worthwhile endeavor, many parents might be inclined to use this science to create designer babies: children who are smarter, taller, or have other supposedly desirable traits. And these tools aren't cheap. They will surely be available to the rich first, creating a terrifying new dimension to the growing economic inequality crisis. Scientists also point out that ‘playing god' and editing genes will alter our DNA code forever, and one mistake could inadvertently introduce new diseases into the human gene pool. While the desire to cure genetic diseases is a noble one, the manipulation of our DNA is more likely than not to push humanity towards a dangerous and dystopian future no one wants.  Arguing for the motion is George Church, Professor of Genetics at Harvard Medical School, Professor of Health Sciences and Technology at Harvard and MIT Arguing against the motion is Joyce Harper, Professor of Reproductive Science at the Institute for Women's Health, University College London.   Sources:  ABC News, France24, Today Show, NBC News, VICE, PBS, Gattaca, Critical Past The host of the Munk Debates is Rudyard Griffiths - @rudyardg.   Tweet your comments about this episode to @munkdebate or comment on our Facebook page https://www.facebook.com/munkdebates/ To sign up for a weekly email reminder for this podcast, send an email to podcast@munkdebates.com.   To support civil and substantive debate on the big questions of the day, consider becoming a Munk Member at https://munkdebates.com/membership Members receive access to our 10+ year library of great debates in HD video, a free Munk Debates book, newsletter and ticketing privileges at our live events. This podcast is a project of the Munk Debates, a Canadian charitable organization dedicated to fostering civil and substantive public dialogue - https://munkdebates.com/ The Munk Debates podcast is produced by Antica, Canada's largest private audio production company - https://www.anticaproductions.com/ Senior Producer: Ricki Gurwitz Editor: Reza Dahya  

By the time he teamed up with Harvard geneticist George Church to found Colossal Biosciences, Ben Lamm had founded, built, and sold five companies. This one would be the most audacious yet: Its goal is to create disruptive conservation technologies, including, to de-extinct the woolly mammoth. Yes, it is actively working to edit elephant genes to create a cold-hearty herbivore to help decelerate melting of the arctic permafrost, and, thus, prevent release of 600 tons of carbon a year. It's also working with existing species-conservation efforts globally–and hopes to apply its technology to save animal populations from going extinct. But with the audacious mission comes a lot of questions–and many critics. Lamm told host Christine Lagorio-Chafkin that he learns more from his detractors than from his supporters–and he welcomes both hearing from them, and, in a couple cases, he's actually hired them to work with him.

In this episode, Peter and Ben discuss the possibility of bringing extinct species back to life through Ben's startup, Colossal.  02:05 | De Extinction: Unveiling Our Future 21:10 | Gene-Swapping for Species Survival 59:32 | The Return of Extinct Species Ben Lamm is a renowned entrepreneur and visionary in technology and AI. With successful startups like Chaotic Moon Studios and Conversable, he has made significant contributions to the industry. As the founder of Hypergiant Industries and Colossal, a venture capital-backed startup focused on genetic engineering and reproductive technology in support of George Church's de-extinction efforts, Lamm continues to push the boundaries of innovation, focusing on AI solutions and genetic engineering. Learn about Colossal. _____________ I only endorse products and services I personally use. To see what they are,  please support this podcast by checking out our sponsors:  Experience the future of sleep with Eight Sleep. Visit https://www.eightsleep.com/moonshots/ to save $150 on the Pod Cover.  _____________ I send weekly emails with the latest insights and trends on today's and tomorrow's exponential technologies. Stay ahead of the curve, and sign up now:  Tech Blog _____________ Connect With Peter: Twitter Instagram Youtube Moonshots and Mindsets Learn more about your ad choices. Visit megaphone.fm/adchoices

A buzzy de-extinction startup is using genetic engineering and restorative biology for big projects — like bringing back the wooly mammoth. Gene-editing pioneer George Church joins us to discuss the venture. Learn more about your ad choices. Visit megaphone.fm/adchoices

In the same way that written English is built around an alphabet of just 26 letters, all life on Earth is built around a standard set of just 20 amino acids, which are the building blocks of all proteins. And just as we've invented special characters like emoji to go beyond our standard letters, it turns out that biologists can expand their repertoire of powers using non-standard amino acids—those that either occur rarely in nature, or that can only be made in the lab. GRO Biosciences, a spinout from the laboratory of the renowned synthetic biology pioneer George Church at Harvard Medical School, is one of the companies working to explore the exciting applications of non-standard amino acids (NSAAs), and Harry's guest this weeks is GRO's co-founder and CEO, Dan Mandell. He says NSAAs could help overcome some of the limitations that keep today's gene and protein therapies from being used more widely, while also expanding the kinds of jobs that protein-based therapies can do.For a full transcript of this episode, please visit our episode page at http://www.glorikian.com/podcast Please rate and review The Harry Glorikian Show on Apple Podcasts! Here's how to do that from an iPhone, iPad, or iPod touch:1. Open the Podcasts app on your iPhone, iPad, or Mac. 2. Navigate to The Harry Glorikian Show podcast. You can find it by searching for it or selecting it from your library. Just note that you'll have to go to the series page which shows all the episodes, not just the page for a single episode.3. Scroll down to find the subhead titled "Ratings & Reviews."4. Under one of the highlighted reviews, select "Write a Review."5. Next, select a star rating at the top — you have the option of choosing between one and five stars. 6. Using the text box at the top, write a title for your review. Then, in the lower text box, write your review. Your review can be up to 300 words long.7. Once you've finished, select "Send" or "Save" in the top-right corner. 8. If you've never left a podcast review before, enter a nickname. Your nickname will be displayed next to any reviews you leave from here on out. 9. After selecting a nickname, tap OK. Your review may not be immediately visible.That's it! Thanks so much.

At the beginning of the year, the company behind the public effort to de-extinct the wooly mammoth announced it will also be de-extincting the dodo. The announcement stirred up a lot of excitement and questions about whether we can – or should – bring back species once they're gone. So this hour we're talking about de-extinction! We'll hear about what it takes to bring back extinct animals, efforts to build a safety net for plants that might go extinct in the future, and walk through some fun de-extinction thought experiments. GUESTS: Helen Pilcher: a science and comedy writer with a PhD in cell biology who wrote Bring Back the King: The New Science of De-extinction Ben Lamm: CEO of the de-extinction company Colossal, which he co-founded with George Church. Carlos de la Rosa: President and CEO of the Center for Plant Conservation Join the conversation on Facebook and Twitter.Support the show: http://www.wnpr.org/donateSee omnystudio.com/listener for privacy information.

Read the full transcript here. What are focused research organizations? Which kinds of research projects lend themselves to the FRO model? Researchers in academia frequently complain about the incentive structures around funding and publishing; so how do FROs change those dynamics? Why must FROs be time-limited, especially if they're successful? Who's in charge in an FRO? How does "field-building" help to improve science? What effects might large language models have on science?Adam Marblestone is the CEO of Convergent Research. He's been launching Focused Research Organizations (FROs) such as E11 bio and Cultivarium. He also serves on the boards of several non-profits pursuing new methods of funding and organizing scientific research including Norn Group and New Science. Previously, he was a Schmidt Futures Innovation Fellow, a consultant for the Astera Institute, a Fellow with the Federation of American Scientists (FAS), a research scientist at Google DeepMind, Chief Strategy Officer of the brain-computer interface company Kernel, a research scientist at MIT, a PhD student in biophysics with George Church and colleagues at Harvard, and a theoretical physics student at Yale. He also previously helped to start companies like BioBright and advised foundations such as the Open Philanthropy Project. His work has been recognized with a Technology Review 35 Innovators Under 35 Award (2018), a Fannie and John Hertz Foundation Fellowship (2010), and a Goldwater Scholarship (2008). Learn more about him at adammarblestone.org. [Read more]

Twitter cut off its API access, and developers of apps like Tweetbot and Twitterrific are offering specific options to help them out. A new iMac is coming out soon? Why can't I access my files from the Google Takeout service? Is there another service I can use to access my Google data? Is there an iOS shortcut for this? The Father of Modern Genomics, Dr. George Church. Lucid dreaming & headphones you can wear to sleep. Is there an easy way to move contacts over to Fastmail? Ant Pruitt & moving from Windows to Mac. Is it worth setting up IoT devices on its own network? Does Apple send out a notification to your old iPhone when your device reaches its end of life? Hosts: Leo Laporte and Mikah Sargent Guest: Ant Pruitt Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit Show notes and links for this episode are available at: https://twit.tv/shows/ask-the-tech-guys/episodes/1964 Download or subscribe to this show at: https://twit.tv/shows/ask-the-tech-guys Sponsors: lectricebikes.com fortra.com

Twitter cut off its API access, and developers of apps like Tweetbot and Twitterrific are offering specific options to help them out. A new iMac is coming out soon? Why can't I access my files from the Google Takeout service? Is there another service I can use to access my Google data? Is there an iOS shortcut for this? The Father of Modern Genomics, Dr. George Church. Lucid dreaming & headphones you can wear to sleep. Is there an easy way to move contacts over to Fastmail? Ant Pruitt & moving from Windows to Mac. Is it worth setting up IoT devices on its own network? Does Apple send out a notification to your old iPhone when your device reaches its end of life? Hosts: Leo Laporte and Mikah Sargent Guest: Ant Pruitt Get episodes ad-free with Club TWiT at https://twit.tv/clubtwit Show notes and links for this episode are available at: https://twit.tv/shows/ask-the-tech-guys/episodes/1964 Download or subscribe to this show at: https://twit.tv/shows/all-twittv-shows Sponsors: lectricebikes.com fortra.com

In a wide-ranging conversation, Leo Laporte talks with Dr. George Church about the history and future of genome sequencing. Dr. Church explains why he is very excited about how they made an organism resistant to all viruses- both known and unknown.   They also talk about:  How Dr. Church made sequencing affordable (from $3BN to $600) Where are we on sequencing the entire human genome, and why would we even want to? How close are we to reversing aging? Should we use gene therapy to double the human lifespan? Why genetically engineering cold-resistant elephants could be important for climate change, and what about ultimately bringing back the Mammoth? He explains the difference between the hype and reality of CRISPR sequencing, synthesis, and delivery What are the privacy concerns about companies sharing your genome? They discuss the controversy and benefit of reconstructing old viruses like the 1918 flu and even inventing new viruses. Dr. Church is a professor of genetics at Harvard Medical School and a pioneer in personal genetics. He is credited with developing the first methods for sequencing the first genome and also the CRISPR technology. He created several companies, including Nebula Genomics and Veritas Genetics. Host: Leo Laporte Guest: Dr. George Church Download or subscribe to this show at https://twit.tv/shows/triangulation.

Could bringing back the woolly mammoth be a key to saving the planet? Tech entrepreneur Ben Lamm and Harvard geneticist George Church are betting on it. Together they launched Colossal Bioscience, a genetic engineering company focused on using gene editing technology to advance de-extinction. But the company has a much larger goal, re-introducing native populations to help restore natural ecosystems. Join us to hear Ben and George talk about their pioneering work. For more information on Colossal go to www.colossal.com.

My new book LOSERTHINK, available now on Amazon https://tinyurl.com/rqmjc2a Find my "extra" content on Locals: https://ScottAdams.Locals.com Content: Charlottesville and Richard Spencer Could I hypnotize AI? Andrew Tate Ben Garrison, my new nemesis George Church aging reversal progress Alzheimer treatment breakthrough ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ If you would like to enjoy this same content plus bonus content from Scott Adams, including micro-lessons on lots of useful topics to build your talent stack, please see scottadams.locals.com for full access to that secret treasure. --- Support this podcast: https://anchor.fm/scott-adams00/support

A genetic disease runs in your family. Your doctor tells you that, should you wish to have a child, that child is likely to also carry the disease. But a new gene-editing technology could change your fate. It could ensure that your baby is -- and remains -- healthy. What do you do? It's is not without its perils. Critics say the technology will exacerbate inequality, pressure all parents (and nations) into editing their children to stay competitive, and meddle with the most basic aspect of our humanity. So, should we use gene editing to make better babies?   Arguing in favor of the motion is geneticist George Church and futurist Amy Webb. Arguing against the motion is policy advocate Marcy Darnovsky and philosopher Françoise Baylis. Emmy award-winning journalist John Donvan moderates.  Learn more about your ad choices. Visit megaphone.fm/adchoices

This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker.All living things are programmed with a certain lifespan, which can be dramatically different from species to species. Humans now, in general, live twice as long as our ancestors, thanks to environmental changes and advances in medicine. But most of us spend the last years of our lives without the quality of life we really want. We've come to identify a slew of symptoms and chronic diseases as a natural part of aging, but do they really have to be?Today I'm excited to talk to Dr. George Church all about the latest science on reprogramming our genes to extend our healthspan and lifespan. Dr. George Church is a professor of genetics at Harvard Medical School, a founding member of the Wyss Institute, and director of PersonalGenomes.org, the world's only open-access information on human genomic, environmental, and trait data. Dr. Church is known for pioneering the fields of personal genomics and synthetic biology. He developed the first methods for the first genome sequence and his team invented CRISPR for human stem cell genome editing and other synthetic biology technologies and applications—including new ways to create organs for transplantation, gene therapies for aging reversal, and gene drives to eliminate Lyme disease and malaria. Dr. Church is the director of IARPA & NIH BRAIN Projects and the National Institutes of Health Center for Excellence in Genomic Science. He is the author of Regenesis.This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker.Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40.InsideTracker is a personalized health and wellness platform like no other. Right now they're offering my community 20% off at insidetracker.com/drhyman.Here are more details from our interview (audio version / Apple Subscriber version):The top things that prevent disease and enhance longevity (7:06 / 4:13) Defining aging as a disease and treating it as such (8:24 / 5:40) Reprogramming and repairing cells to a younger state (12:24 / 9:35) The future, and challenges, of delivering Yamanaka factors for cell reprogramming (15:05 / 11:50) Gene editing vs gene therapy (28:02 / 22:36) Using gene therapy to reverse disease and lengthen life span (34:44 / 30:55) Animal-to-human organ transplants (37:34 / 33:04) Can we live youthfully to 100 years old and beyond? (44:31 / 40:34) How much and what types of protein do we need for healthy aging? (50:30 / 45:50) Using gene editing to bring back mammoths to restore damaged ecosystems (1:00:53 / 56:50) Get a copy of George Church and Ed Regis' book, Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves, here. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology.  In this episode, we discuss: 07:13 - History of the Human Genome Project 15:20 - Manufacturing cell phones (with biology) 17:34 - Genome Project-Write 20:03 - Writing a human Y chromosome (from scratch) 20:48 - What if you could eliminate viral disease? 22:51 - De-extinction and reinstating lost traits and genes 27:06 - The Vertebrate Genomes Project 29:47 - AlphaFold and other AI tools 41:27 - CRISPR vs. Base Editing (emerging tools of genetic engineering) 49:40 - Why multiplex editing will change the world 52:18 - Molecular flight recorder 53:31 - Preventing viral spillover and enhancing livestock 57:40 - PCSK9 gene therapy for cholesterol 01:00:30 - Is aging an evolved program? 01:05:21 - Treating aging with a combination gene treatment 01:09:04 - Does animal research help us understand human aging? 01:11:40 - Human organoids as a model and therapeutic 01:13:34 - Could engineered transplant organs become better than the originals? 01:16:17 - Embryo editing controversy 01:28:41 - Gene editing for space travel 01:30:40 - Can synthetic biology alleviate poverty? 01:34:07 - Is in vitro fertilization and embryo selection practically similar to editing? 01:39:12 - The occasional cost of brilliance 01:45:45 - Eradicating disease with Gene Drive 01:48:55 - Technologies to solve Lyme disease 01:51:57 - Dr. Church's experience with narcolepsy as a bridge to creative insights 02:00:42 - Why George encoded his book in DNA Watch this episode on YouTube Show notes are available by clicking here Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more: https://www.foundmyfitness.com/premium Learn more about the premium podcast The Aliquot: https://www.foundmyfitness.com/aliquot