Podcasts about sits

-It's not the most flattering thing to be listed as the 10 th best coach in the conference---and that's why the league has become soformidable the last few years-The top 10 in order: Curt Cignetti, Ryan Day, Dan Lanning, Kyle Whittingham, Kirk Ferentz, Lincoln Riley, Bret Bielema, Jedd Fisch, MattCampbell, Matt Rhule. A major upset….Barry Odom is NOT dead last at Purdue…who is, though?Our Sponsors:* Check out Hims and use my code hims.com/EARLYBREAK for a great deal: https://www.hims.com* Check out Progressive: https://www.progressive.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

  If life keeps speeding up and the demands keep stacking up (kids, parents, work, your own busy brain) then this one's for you. In this episode I interview speaker, writer and self-development expert Lily Silverton about her book Prioritize This: A Practical Guide for Thriving in a World That Won't Slow Down. We dig into three chapters that land hardest for the midlife squeezed middle: stress, overwhelm, and procrastination and some practical, brain-based tools for each. Lily is candid about her own experiences navigating the combination of a seriously ill father and young children, and why she has no time for self-help advice written for people with no heed for the demands of real life. We discuss: The two most robust, evidence-backed interventions — movement and social connection. Building your own bespoke stress toolkit (the "pick and mix", not the prescriptive programme) SITs and SATs: stress-inducing vs stress-alleviating thoughts, and turning the dial down on catastrophising The multitasking myth — why it's really task switching, and what each switch costs you Three questions to cut through overwhelm Procrastination as emotional management, not time management - aka "what feeling am I avoiding?" AI, the hamster wheel, and whether technology will actually save us time... Resources and Links: Lily's books: Prioritize This and The Priorities Method journal Exercises and downloads at the Prioritize This website: https://www.prioritisethis.com/ Instagram: @lily_silverton Website: lilysilverton.com Substack: https://prioritisethis.substack.com/ Don't forget you can find out how to work with me and the back archive of this podcast at www.thetripleshift.org/starthere - and if you enjoyed this episode please do write us a short review to help others discover Middling Along!

It's Monday, June 15. Here are today's top stories around Central Indiana. Want to go deeper on the stories you hear on WFYI News Now? Visit wfyi.org and follow us on social media to get local news every day. WFYI News Now is hosted by Barb Anguiano and produced by Zach Bundy. Subscribe wherever you get your podcasts.

In this SITS classic from 2017, we speak with Mark O'Connell. With UFOs once again dominating headlines through government hearings, whistleblower claims, and renewed public interest, we're revisiting this conversation with O'Connell about his book,The Close Encounters Man: How One Man Made the World Believe in UFOs, chronicling the life of legendary astronomer Dr. J. Allen Hynek. Originally hired by the Air Force to debunk UFO sightings, Hynek's years investigating unexplained cases led him to a startling conclusion: UFOs deserved serious scientific attention. Through unprecedented access to Hynek's personal and professional files, including his time working with Steven Spielberg, O'Connell paints a compelling portrait of the man who transformed from skeptic to pioneer in UFO research. At a time when many of the same questions Hynek raised decades ago are resurfacing today, this episode remains more relevant than ever. Buy the book: https://amzn.eu/d/05vp8xtW Use promo code: SOMEWHERE15 for 15% OFF Anomalous Cards: https://www.letsgetanomalous.com/ Send us a voicemail with questions, comments, or topic suggestions: https://www.speakpipe.com/SomewhereSkiesPod Patreon: http://www.patreon.com/somewhereskies ByMeACoffee: http://www.buymeacoffee.com/UFxzyzHOaQ Substack: https://ryansprague.substack.com/ All socials and books: https://linktr.ee/somewhereskiespod Follow Suzanne on X: https://x.com/csuzannelanders Email: ryan.sprague51@gmail.com Opening theme song by Septembryo Closing song by Per Kiilstofte Copyright © 2026 Ryan Sprague. All rights reserved. #DisclosureDay #UFO #UAP #SomewhereInTheSkies #JAllenHynek #UFOPodcast #AlienLife #Disclosure #ParanormalPodcast Learn more about your ad choices. Visit megaphone.fm/adchoices

Andy Hooser The Voice of Reason fills in for Mark

Five-time Grammy Award-winning artist CeeLo Green joins Rickey Smiley On The Spot for one of the most entertaining and insightful conversations yet. This conversation originally took place on the Rickey Smiley On The Spot podcast, CeeLo dives into Atlanta's influence on music, the rise of Dungeon Family, and the lessons he's learned throughout his incredible journey of working with Kanye, Outkast, and more. Listen to the full interview on Apple Podcasts: Listen On Apple Podcasts Spotify: Listen On Spotify CHAPTERS (00:25) - Intro (02:23) - The truth about joining Outkast (03:34) - Filling in for Big Boi & joining Goodie Mob (04:33) - The origins of Gnarls Barkley (05:31) - Connecting with Danger Mouse in Athens (06:59) - Collaborating with Kanye West on "Bully" (10:10) - Performing "Bully" at SoFi Stadium ABOUT THE PODCAST Rickey Smiley On The Spot is Rickey in his truest form — Authentic. Funny. Heartfelt. Honest. Each episode brings audiences up close with one of comedy’s most trusted voices as he dives into real conversations that mix humor with humanity.See omnystudio.com/listener for privacy information.

6-12 Adam and Jordana 9a hour

Rishi Chhatwal, Partner at EDRM Trusted Partner Redgrave LLP, sits down with EDRM's Mary Mack and Holley Robinson. In this episode, Rishi talks about his journey to eDiscovery through two major corporate accountabilities coupled with high-level consulting prior to joining the team at Redgrave. Rishi talked about scaling eDiscovery, not only at a traditional technology company like AT&T, but also at Coinbase, a newer company positioned at the intersection of finance, bitcoin, and regulation. We ended with Rishi's surprising fun fact and an invitation to contact him.

Tyler Callihan had an absolute legacy performance to fuel the Pirates' comeback against the Dodgers yesterday. However, Callihan is not in the lineup today because there is a lefty on the mound. Jared Triolo and Marcel Ozuna are both in the lineup tonight, as they both hit lefties well. Bob Pompeani joined the show. Bob says that he will watch the World Cup from time to time this year. Bob does not think that the division is out of reach for the Pirates, and he thinks that the Pirates will be involved in the playoff race this year. Bob also thinks that Mitch Keller will put together a nice performance tonight against the Dodgers. He says that the Pirates have to wait for Marcel Ozuna to do more considering what they paid him this offseason. Steelers insider Ray Fittipaldo joins the show. Ray thinks that the backup QB job is solely in Will Howard's hands, and there is nothing Mason Rudolph can do if Howard performs well enough to be the backup. Ray says that Drew Allar has been up and down this year, but there is still a lot of optimism surrounding him. Ray says that a Joey Porter Jr contract will be more expensive than Nick Herbig's $25 million.

June 11, 2026 ~ Lloyd Jackson and Jason Roe speak with Michigan policy advocate Lindsay Palsrok. She shares her family's struggle with kratom addiction. Palsrok discusses the push for legislative action to ban kratom sales in Michigan. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

and testings their quizzin' brains its Malcolm in Hastings and Sarah in Oxfordshire!

Laura Eisenhower, The Great Grabddaughter of President And General Eisenhower, Sits down with Ty on Total Disclosure. From The Hidden and Unseen ALIEN AGENDA, to the Awakening of a New Consciousness globally. This Conversation Dives into the More, mystical and Magical, Blended with The UAP disclosure Effort Happening right now in the World. From President Trump Declassifying Videos, to Secret Space programs being exposed. 

Taylor Johnson presents a mixtape of tracks from BBC Introducing, including Wynona Bleach, Ashley Ray Simon feat. Clara Pople, Lizzie Reid, Formal Sppeedwear, F3miii, mary in the junkyard, LIFEWITHOUTEXPOSURE, Victoria Dell, Sipho., Naked Brunch, Joshua Burnside, Ella More, and a new Track of the Week from Dose.Produced by BBC Audio for BBC Radio 6 Music.

Dave Rubin of "The Rubin Report" talks about Donald Trump humiliating CNN's Kaitlan Collins and exposing her conservative Fox News past in front of her peers in the White House Press Corp after she pushed Trump on the current status of the Anti-Weaponization fund; Fox News' Laura Ingraham demanding a federal investigation into California elections after Spencer Pratt and Steve Hilton's status remains undecided due to a large numbers of votes remaining to be counted despite the election being days ago; "The View's" Sunny Hostin looking like a hypocrite after revealing that she has changed her mind on whether she would vote for Graham Platner in Maine to oust Susan Collins; Democrat John Fetterman abandoning Democrat talking points and denouncing Graham Platner for his mounting scandals including his Nazi tattoo and now his use of the Kik app; CNN's Harry Enten sharing new polling data that should scare Democrats who think that Graham Platner can defeat Susan Collins in Maine to give Democrats control of the Senate; and much more. Dave also hosts a special "ask me anything" question-and-answer session on a wide range of topics, answering questions from the Rubin Report Locals community.   Today's Sponsors: Relief Factor - Relief Factor is an alternative to help your body's natural inflammatory response causing the achy, soreness, stiffness, and discomfort from daily living that keeps you from doing the things you love. Try Relief Factor's 3-Week QuickStart—just $19.95. Go to: https://www.relieffactor.com or call 800-4-RELIEF. DeleteMe - Remove your personal information from hundreds of data broker and people search sites, so your data is far less likely to end up in the wrong hands. Get 20% off DeleteMe and protect your privacy! Go to: https://joindeleteme.com/RUBIN and use code RUBIN Mars Men - A potent and natural testosterone stack that optimizes your body's ability to forge usable testosterone. For a limited time, our listeners get 50% off FOR LIFE AND 3 Free Gifts at Mars Men when you use code RUBIN . Go to: http://Mengotomars.com

On April 26, 2026 at the Mall of Louisiana, gunfire erupted in the food court. BRPD Sergeant Billy Aime sits down with Kiran Chawla as he describes being the first officer on scene, relaying warnings over radio, and finding victims amid the chaos. Aime also recounts providing basic first aid, assisting with evacuation, and working with other officers and mall staff to clear the building.He discusses the death of 17-year-old Martha Odom, visiting victims in the hospital, and the recovery of wounded mall regular Donnie Guillory.Timestamps05:27 Food Court Chaos07:06 Protecting the Mall10:44 Donnie in the Crossfire14:30 Securing the Entire Mall23:13 Visiting the Victims30:07 Back to Work33:18 Donnie's Recovery38:48 Carrying the Guilt43:33 Attack Years EarlierLocal Sponsors for this episode include:Neighbors Federal Credit Union:Another Chance Bail Bonds:Family Worship Center ChurchTwin Team RealtyIf you are looking to buy or sell your home, look no further! Call (225) 354-9761 Today!Sound and Editing for this audio podcast by Envision Podcast Production:

The Prep convo for ya 20's, 30's and 40'sIts ya girl earth day.Sip something good for me.Its Chan and SHE Gets It PodSubscribe / Share the episode / Follow @chanbepoddin / Leave a review~~~Enjoy Chan on the mic and supporting sponsors: TableTopics.com click herehttps://www.tabletopics.com/CHANTAL85549https://www.bonfire.com/store/the-chanbepoddin-spot/~~~Follow us for more information:IG & X: @chanbepoddin Visit chanbepoddin.com Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

In this Somewhere in the Skies classic, Ryan revisits a fascinating conversation with author and researcher, Mike Clelland, about his influential book, The Messengers: Owls, Synchronicity, and the UFO Abductee. Drawing from countless firsthand accounts, Clelland explores the mysterious connection between owls and UFO encounters, uncovering patterns that challenge conventional explanations. The conversation delves into the strange overlap between alien contact experiences, synchronicities, dreams, archetypes, spiritual transformation, and even death. Blending folklore, personal testimony, and his own experiences, Clelland examines the possibility that owls play a profound and symbolic role in some of humanity's most extraordinary encounters with the unknown. Buy the book: https://a.co/d/0d402jip Use promo code: SOMEWHERE15 for 15% OFF Anomalous Cards: https://www.letsgetanomalous.com/ Send us a voicemail with questions, comments, or topic suggestions: https://www.speakpipe.com/SomewhereSkiesPod Patreon: http://www.patreon.com/somewhereskies ByMeACoffee: http://www.buymeacoffee.com/UFxzyzHOaQ Substack: https://ryansprague.substack.com/ All socials and books: https://linktr.ee/somewhereskiespod Follow Suzanne on X: https://x.com/csuzannelanders Email: ryan.sprague51@gmail.com Opening theme song by Septembryo Closing song by Per Kiilstofte Copyright © 2026 Ryan Sprague. All rights reserved. #Owls #Owl #synchronicity #alien #alienabduction #UFOs #UFOlogy #UAP #Paranormal Learn more about your ad choices. Visit megaphone.fm/adchoices

Who let G-dog Aaron loose and who would dare fact check Eric besides Joe Zappa?!! In this engaging interview, industry veteran Aaron discusses his journey from sales to marketing, the importance of personal branding, and the evolving role of AI in ad tech. He shares insights on strategic acquisitions, building a personal brand, and the creative side of marketing, all while revealing his unique personality and passions. We also learn what Eric would have done had he not become a VC. Let's just say no one saw this riding in!

Facebook whistleblower Sarah Wynn-Williams sat in silence and did not speak at a panel discussion about her tell all book about the social media giant because of ongoing legal action by her former bosses at Meta. Jessica Kelly Newstalk's Technology Correspondent brought us the details.

Shawn Johnson graduated from Winona State University in Winona, Minnesota, with a degree in Criminal Justice before earning his Juris Doctorate from William Mitchell College of Law in St. Paul, Minnesota. He was immediately accepted into the FBI, trained at the FBI Academy, and assigned to the Seattle Division. There, he worked on the Green River Serial Murder investigation before joining the Violent Crimes Squad, where he investigated bank robberies, fugitives, interstate theft, extortions, and kidnappings. His legal background also led to service as Assistant Chief Division Counsel. Johnson later joined the National Security Squad, working counterterrorism and counterintelligence operations, including joint overseas investigations with the United States Army and the Royal Canadian Mounted Police. Returning to the Violent Crimes Squad, he played a key role in the Hollywood investigation, helped establish the Puget Sound Violent Crime Task Force, served as Bank Robbery Coordinator, and authored the Division's Bank Robbery Response Plan. After transferring to the Milwaukee Division's Madison Resident Agency, he focused on drug conspiracy investigations, employing sophisticated surveillance techniques that contributed to major takedowns of drug organizations in Chicago and Madison. Following 9/11, he managed the newly established Madison Joint Terrorism Task Force (JTTF), overseeing federal and local efforts to investigate international terrorism. Johnson later returned to the FBI Academy in Quantico, Virginia, where he instructed new agents in criminal investigations, counterterrorism investigations, and Human Intelligence (HUMINT). His final FBI assignment was with the Directorate of Intelligence, training agents in HUMINT policy and procedures. Upon retiring from the FBI, he founded Wolf & Owl LLC, where he continues to train FBI personnel in support of the Bureau's mission to protect the United States. Steven Meyers was the partner and principal accomplice of Scott Scurlock, better known as "Hollywood," the notorious bank robber responsible for a string of high-profile bank heists in the Seattle area during the 1990s. Over the course of four and a half years, Meyers worked closely with Scurlock and their crew in planning and executing 19 bank robberies that resulted in the theft of more than $2.3 million. Beyond participating in the operation, Meyers helped develop the plans, create disguises, and support the methods that allowed the crew to evade law enforcement for years. Meyers and Scurlock were deeply involved in every aspect of the enterprise, including planning operations, laundering money, and acquiring vehicles and equipment. As Scurlock's closest collaborator, Meyers gained a unique understanding of the man behind the "Hollywood" persona and the motivations that drove one of the Pacific Northwest's most infamous crime sprees. In 2023, Meyers was featured in the Netflix documentary *How to Rob a Bank*, providing firsthand insight into the robberies and the inner workings of the crew. Today, he joins retired FBI Special Agent Shawn Johnson—the lead investigator who helped solve the case—to share the untold stories behind the Hollywood robberies and offer perspectives from both sides of one of the most remarkable bank robbery investigations in modern history.See omnystudio.com/listener for privacy information.

"McElroy & Cubelic In The Morning" airs 7am-10am weekdays on WJOX-94.5!See omnystudio.com/listener for privacy information.

Our BYU Insider Mitch Harper joined the show to recap what he took away from Big 12 Spring Meetings. What are the vibes for the conference in this era of college football? 

Rob McBride, Urban Meyer, and Kyle Whittingham -- all legendary head football coaches for the Utah Utes. And now, a new head coach has taken the helm: Morgan Scalley. He sat down with KSL Podcasts' new show "Coaches' Book Club" to talk about the book that's influenced his life and his coaching: "Ego is the Enemy" by Ryan Holiday. Co-host of "Coaches' Book Club" Amy Donaldson joins Inside Sources with more on today's new episode with the head coach of the Utah Utes.

(5) James Tabor describes Mount Zion in Jerusalem as the world headquarters of the early movement. Archaeological evidence suggests the "Upper Room" sits atop a first-century foundation of a house-synagogue. In this space, Maryserved as a matriarch and hostess, greeting early pilgrims and figures like the Apostle Paul. This segment portrays a vibrant Jerusalem-based community where the "genius" of the early church thrived. Tabor envisions the household dynamics on Mount Zion, where Mary remained a central figure of authority, hospitality, and memory following the death of her son.1787 Death of Socraates

Rep. John Ley of the 18th Legislative District calls out Washington State's failure to open the Brockmann Campus — a completed, $42 million, 48-bed mental health facility north of WSU Vancouver that received only $600,000 for a "warm closure" instead of clinical operations. Advocates say the delay is costing lives. https://www.clarkcountytoday.com/opinion/opinion-the-challenges-of-getting-the-brockmann-mental-health-facility-open/ #BrockmannCampus #MentalHealth #WashingtonState #ClarkCounty #DSHS #CivilCommitment #MentalHealthAwarenessMonth #PublicPrivatePartnership #SouthwestWashington ---

As today's UFO conversation becomes increasingly centered on American military footage and government hearings, it's important to remember that this phenomenon has never respected borders. In this re-release of Somewhere in the Skies, Ryan revisits the 2004 Mexican Air Force UFO encounter, where infrared cameras aboard a military patrol aircraft captured multiple unknown objects during an official mission. Along with military testimony, radio transmissions, and reports delivered to Mexico's Secretary of Defense, the case remains one of the strongest examples of UFO activity beyond the United States. Joined by researcher Ruben Uriarte, Ryan explores extraordinary cases spanning Mexico and the American Southwest, including the Cisco Grove encounter, the Carlos de los Santos incident, and the rumored Coyame UFO crash. Revisiting this conversation today serves as a reminder that the UFO mystery is global, deeply human, and far bigger than any one country's narrative. Follow Ruben Uriarte's work: https://www.amazon.com/Books-Ruben-Uriarte/s?rh=n%3A283155%2Cp_27%3ARuben%2BUriarte Use promo code: SOMEWHERE15 for 15% OFF Anomalous Cards: https://www.letsgetanomalous.com/ Send us a voicemail with questions, comments, or topic suggestions: https://www.speakpipe.com/SomewhereSkiesPod Patreon: http://www.patreon.com/somewhereskies ByMeACoffee: http://www.buymeacoffee.com/UFxzyzHOaQ Substack: https://ryansprague.substack.com/ All socials and books: https://linktr.ee/somewhereskiespod Email: ryan.sprague51@gmail.com Opening theme song by Septembryo Closing song by Per Kiilstofte Copyright © 2026 Ryan Sprague. All rights reserved. #Mexico #Southwest #Coyame #UFO #UFOs #UFOcrashes #UAP #Alien #CiscoGrove #AlienEncounters Learn more about your ad choices. Visit megaphone.fm/adchoices

A day after departing as Essendon coach, Brad Scott sits down for an extended interview with Cal Twomey.See omnystudio.com/listener for privacy information.

Your life is already worship-shaped. The only question is what's doing the shaping. Join Kelly, Jodi &  Mattea as they dive into this topic!Thanks for listening!  Follow us on Facebook or YouTube.

Jim McTague describes robust Memorial Day shopping in Lancaster County despite high gas prices. He warns that the economy sits in bubbles created by AI data centers and government spending. (5/16)1900 HOTEL RAMONA LA, THIRD AND SPRING

SBS speaks with independent MP Allegra Spender to discuss the recent federal budget

May 22, 2026- On the latest Dispatches from Planet Albany, New York Working Families Party Director Jasmine Gripper explain why her organization is sitting out the Democratic primary for state comptroller and highlights their effort to influence the state senate.

Spencer Pratts campaign is getting attention all over the world at this point.See omnystudio.com/listener for privacy information.

We start with sources telling CNN that Iran is rebuilding their military capabilities faster than expected.  SpaceX files for an IPO that could make Elon Musk a trillionaire. Former Cuban President Raul Castro has been indicted for allegations from 30 years ago. CNN speaks to L.A. mayoral candidate Spencer Pratt. Plus, people are getting creative to beat inflation and high gas prices.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

Spencer Pratts campaign is getting attention all over the world at this pointSee omnystudio.com/listener for privacy information.

Top 100 CFB stories as the CFB season sits 100 days away full 433 Thu, 21 May 2026 23:34:20 +0000 L4zoMwnhED1yDZrXGukMZD09BfX1ioYm ncaa football,college football,sports GBag Nation ncaa football,college football,sports Top 100 CFB stories as the CFB season sits 100 days away GBAG Nation sets the afternoon sports pace for Dallas-Fort Worth with an energetic, roundtable approach that speaks directly to the heart of North Texas. Featuring Gavin Dawson, Super Bowl winning scout Bryan Broaddus, Eric Chiofalo, Zach Wolchuk and Lucious Alexander, the show combines insider-level knowledge, strong debate, and the confident swagger of the Metroplex, plus plenty of laughs and the kind of friendly ribbing you'd expect from a group of best friends. Your drive home is filled with in-depth coverage of the Cowboys, Rangers, Mavericks and Stars. GBAG Nation also tracks college football across Texas along with the biggest national sports headlines, translating them through a distinctly local lens. The GBAG Nation has some of the best contacts in DFW. They pull back the curtain and give you information that no one else can. This is where informed analysis meets bold opinion, with humor and camaraderie that keep it fun and real. © 2026 Audacy, Inc. Sports https://player.amperwavepodcasting.com

On this classic episode from the archives, Ryan is joined by researcher and psionics experimenter Susan Demeter-St. Clair to explore the connection between UFO encounters, consciousness, and the paranormal. Drawing from her own close encounter and decades of research into telepathy, symbolism, and “high strangeness,” Susan challenges the traditional nuts-and-bolts view of UFOs. From shared psychic experiences to UFO events linked to poltergeist activity, this conversation asks a provocative question: if UFOs are interacting directly with the human mind, what are they trying to communicate? Follow Susan's work at: https://susandemeter.wordpress.com/ Use promo code: SOMEWHERE15 for 15% OFF Anomalous Cards: https://www.letsgetanomalous.com/ Send us a voicemail with questions, comments, or topic suggestions: https://www.speakpipe.com/SomewhereSkiesPod Patreon: http://www.patreon.com/somewhereskies ByMeACoffee: http://www.buymeacoffee.com/UFxzyzHOaQ Substack: https://ryansprague.substack.com/ All socials and books: https://linktr.ee/somewhereskiespod Email: ryan.sprague51@gmail.com Opening theme song by Septembryo Closing song by Per Kiilstofte Copyright © 2026 Ryan Sprague. All rights reserved. #UFOs #Parapsychology #Paranormal #Psionics #UAP #Psychic #UFOlogy Learn more about your ad choices. Visit megaphone.fm/adchoices

Do you ever feel like you can't sit still, even when you finally have the time? Whether it's a moment on the couch, an evening at home, or a free weekend, your brain might be urging you to do one more thing, check one more box, or finish just one more task. What happens when rest feels uncomfortable instead of relieving?     In this episode, I explore why high-achieving women struggle to slow down, why productivity becomes a form of emotional regulation, and how constantly pushing yourself starts to feel necessary, not optional. I share how internalized rules about usefulness and worth make stillness feel threatening, why rest is often delayed until complete exhaustion, and how even small pauses can feel impossible when your nervous system is wired for constant motion.   Get full show notes, transcript, and more information here: https://carriehollandmd.com/204   Follow me on Facebook and Instagram: https://www.facebook.com/carriehollandmd https://www.instagram.com/carriehollandmd/

And it does not go well at all, not on fires or homelessnessSee omnystudio.com/listener for privacy information.

Richard Harris sits down with Joshua Philipp of The Epoch Times at the National Religious Broadcasters for a conversation on media, culture, and the importance of truth in today's world. In this interview, Joshua shares insight from his work in journalism, discussing current issues, the role of media in shaping public understanding, and the need for discernment in a rapidly changing information landscape. The discussion highlights faith, integrity, and the responsibility of those communicating truth.Subscribe to our newsletter: https://www.truthandliberty.net/subscribe  Donate here: https://www.truthandliberty.net/donate  

Mary Mandefield hosts a discussion centred around women's ens health, navigating diagnosis, advocating for yourself and what healing looks like. Mary will be joined by: 1Xtra family, broadcaster and entrepreneur Sian Anderson. Speaking about navigating her recent PCOS and fibroids diagnosis.Comedian and writer Kyrah Gray, speaking candidly about her PMDD diagnosis and the emotional toll of navigating women's health conditions that are so often misunderstood.Content creator Frankie Parker, opening up about living with Premature Ovarian Insufficiency (POI) and the complex conversations around fertility and long-term health as a young woman.General Practitioner, educator, speaker and health content creator, Dr Aziza Sesay. Talks us through all the medical terms, advises how to advocate for yourself at the doctors and advises when to seek a specialist. Produced by Unedited for BBC Radio 1Xtra.

In episode 2059, Jack and Miles are joined by producer and beauty influencer, Carmen Laurent, to discuss… Daddy Bloodbag’s Secrets to Eternal Life Have Dropped, Rudy Giuliani saw everything BUT God, Please Keep RFK Jr Away From Heart Surgeries, OpenAI’s Children’s Movie/Investor Bait Is For Sale At Cannes and more! Carmen's Piece of Media: "Just give me a fan!" Bryan Johnson's list of 41 things he's learned while 'spending millions' on longevity Giuliani Reveals ‘Spiritual Experience’ While in Coma Fact Check: Did RFK Jr Perform Heart Surgery on a Live Patient in Ohio? RFK Jr. Sits in on Open Heart Surgery in Bonkers Move Thierry Frémaux Talks New Oscar Rules, “Feminist Washing” ‘Thelma & Louise’ Poster Charge; Berlinale Backlash, AI, Red Carpet Selfies & Hollywood Film industry cannot fight rise of artificial intelligence, says Demi Moore AGC Launches Open AI-Produced Animated Family Film ‘Critterz’ For Cannes Market IMDB: Critterz ‘Critterz’ First Look: New Tech Behind AI Animated Feature Unveiled as Vertigo and Federation Form New AI Production Company “This future looking like a nightmare”: OpenAI announces feature-length AI-generated film, “Critterz,” and nobody wants this OpenAI Backs AI-Made Animated Feature Film If making a movie with AI still costs 30 MILLION then AI-generated “art” is an objective failure. French Filmmaking Organizations Condemn OpenAI-Backed Animated Feature Aiming For Cannes LISTEN: sleeptalkin by Black Light AnimalsSee omnystudio.com/listener for privacy information.

Aday sits with Andy Katz and Michigan vs Duke in limboSee omnystudio.com/listener for privacy information.

Former Atlanta mayor and gubernatorial candidate Keisha Lance Bottoms joins Rickey Smiley for a conversation about the current political climate, voting rights, and why civic engagement is more important than ever. Keisha speaks candidly about the challenges facing democracy and the importance of showing up, staying informed, and being intentional about the future. Keisha shares her vision, what drives her, and why this moment matters. This conversation originally took place on On The Spot with Rickey Smiley, where Keisha Lance Bottoms joins Rickey Smiley for a powerful and wide-ranging conversation on On The Spot. From growing up in Atlanta to serving as mayor and later advising in the White House, Keisha shares her journey through leadership, public service, and the moments that shaped her path. Listen to the full interview on Apple Podcasts: Listen On Apple Podcasts Spotify: Listen On Spotify Learn more about the podcast: https://www.urban1podcasts.com/rickey-smiley-on-the-spot ABOUT THE PODCAST Rickey Smiley On The Spot is Rickey in his truest form — Authentic. Funny. Heartfelt. Honest. Each episode brings audiences up close with one of comedy’s most trusted voices as he dives into real conversations that mix humor with humanity.See omnystudio.com/listener for privacy information.

She Sought Out the People Who Threatened Her Deeyah Khan was editing a film when the BBC called. The threats were serious enough the police were already on their way. “Stay where you are,” they told her. “If there are windows in the room, move to a different one. Wait for us.” She had given an interview saying Britain would never be all white again. White supremacist sites in the United States picked it up and ran with it. One of those sites had been frequented by Dylann Roof, the man who murdered nine Black parishioners in Charleston in 2015. Now their followers were sending death threats by the hundreds, telling her to be afraid, telling her she should not exist. The police gave her a personal alarm and a security briefing. That night, sitting alone, she made an unusual decision. She would not hide. She would seek out the people threatening her, sit with them face to face, and try to understand who they were. I had the privilege of speaking with Deeyah recently on Cults, Culture & Coercion. She is a BAFTA and two-time Emmy winning documentary filmmaker. Over the past fifteen years, she has done what almost no one in journalism has been willing to do. She has interviewed convicted anti-abortion terrorists from the Army of God, the leader of America's oldest and largest neo-Nazi organization, and pro-Trump militia members plotting violence against refugees. She has done it warmly, with genuine curiosity, while also holding strong positions of her own about human rights, women's rights, and the basic dignity of every person. She is an inspiration and she has, but being respectful snd curious and asking questions without attacking, has been able to help deradicalize a major figure in the hate cult. Please read this blog on Substack and listen to this amazing interview. Learn more about your ad choices. Visit megaphone.fm/adchoices

With Boomer out, Gio and Jerry break down the Knicks dodging a bullet with OG Anunoby, who likely sits tonight as they handle the Sixers. We look ahead at other NBA matchups. C-Lo updates OG's status, followed by Dave Sims' call of Trent Grisham's big double and Jasson Dominguez heading to the IL. Finally, the Mets lose to the Rockies on a grand-slam, and we dive into what's left to learn about the Dianna Russini and Mike Vrabel situation.

From 05/04 Hour 4: CK joins The Sports Junkies.