Podcasts about Hypersomnia

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/professional-recommendations-of-clinically-validated-tools-used-to-monitor-response-to-treatment-in-idiopathic-hypersomnia/17914/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Evidence-based Discussion of the New and Emerging Treatment Strategies for Idiopathic Hypersomnia

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/evidence-based-discussion-of-the-new-and-emerging-treatment-strategies-for-idiopathic-hypersomnia/17915/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Evolving Treatment Paradigms in Idiopathic Hypersomnia

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/evolving-treatment-paradigms-in-idiopathic-hypersomnia/17913/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Challenges in Recognizing and Diagnosing Idiopathic Hypersomnia

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/challenges-in-recognizing-and-diagnosing-idiopathic-hypersomnia/17908/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Patient Testimonial: A Day In the Life of an Idiopathic Hypersomnia Patient

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/patient-testimonial-a-day-in-the-life-of-an-idiopathic-hypersomnia-patient/17912/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Evaluating and Promoting Health in Idiopathic Hypersomnia: Beyond Sleepy

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/evaluating-and-promoting-health-in-idiopathic-hypersomnia-beyond-sleepy/17911/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Idiopathic Hypersomnia and Cardiovascular Health: Too Much of a Good Thing?

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/idiopathic-hypersomnia-and-cardiovascular-health-too-much-of-a-good-thing/17910/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Idiopathic Hypersomnia Insights: A Diagnostic Case Study

Play Episode Listen Later Jan 12, 2024

CME credits: 1.00 Valid until: 12-01-2025 Claim your CME credit at https://reachmd.com/programs/cme/idiopathic-hypersomnia-insights-a-diagnostic-case-study/17909/ The goal of this program is to address the unmet clinical needs associated with enhancing the accuracy and timeliness of diagnosing Idiopathic Hypersomnia (IH), acknowledging the cardiovascular implications of IH, and developing a comprehensive treatment strategy. This curriculum incorporates compelling patient video vignettes that convey the perspective of individuals living with IH and the profound impact that it has on their lives. This program aims to not only educate healthcare professionals on the rapidly evolving field but also to bring about positive changes in clinical practice, ultimately leading to an enhanced quality of life for individuals affected by IH.

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Pathophysiology of Idiopathic Hypersomnia

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Play Episode Listen Later Aug 17, 2023 14:40

While the pathophysiology of idiopathic hypersomnia is unknown, emerging science suggests that nighttime sleep dysfunction may contribute to daytime sleepiness in patients with idiopathic hypersomnia. A systematic review and meta-analysis that included 10 studies found that, on average, several sleep architecture hallmarks were different in patients with idiopathic hypersomnia relative to controls.Total sleep time and percent of REM sleep were increased in patients with idiopathic hypersomnia compared with controls.Sleep-onset latency and percent of slow-wave sleep were decreased in patients with idiopathic hypersomnia compared with controls.Sleep efficiency and REM latency were similar between patients with IH and controls.In addition to nighttime sleep dysfunction, other physiological changes have been observed in some patients with idiopathic hypersomnia and theorized as possible contributors to its pathophysiology including:Dysfunction of the GABAergic systemAutonomic system dysfunctionAltered functional or regional connectivity in the brainCircadian system dysfunctionDysfunction of energy metabolismThis episode is produced by Sleep Review and is episode 5 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information. In episode 5, listen as Sleep Review's Sree Roy and neurologist-sleep specialist Isabelle Arnulf, MD, PhD, discuss:Science doesn't fully understand the pathophysiology of idiopathic hypersomnia. Research has revealed potential clues, however. For example, idiopathic hypersomnia is associated with changes in sleep staging and architecture. What does emerging science suggest are differences in nighttime sleep?How might the arousal index differ in idiopathic hypersomnia versus in people without it, and why might that matter?In addition to nighttime sleep dysfunction, other physiological changes have been observed in some patients with idiopathic hypersomnia and theorized as possible contributors to its pathophysiology. What is the GABAergic system and its possible role?What are some emerging findings surrounding idiopathic hypersomnia and autonomic system dysfunction?What is the evidence that supports the idea of altered functional or regional connectivity in the brain in people with idiopathic hypersomnia?There were fascinating studies done on skin fibroblasts, suggesting that circadian period length may be different in people with idiopathic hypersomnia versus in people without it. What role might circadian rhythm dysfunction have in idiopathic hypersomnia?What has science discovered about the possible role of dysfunction of energy metabolism in idiopathic hypersomnia?What further research would you like to see conducted on the pathophysiology of idiopathic hypersomnia?Listen to Episode 1: Symptoms of Idiopathic HypersomniaListen to Episode 2: Diagnosis of Idiopathic HypersomniaListen to Episode 3: Differential Diagnosis of Idiopathic HypersomniaListen to Episode 4: Burden of Idiopathic Hypersomnia

Pathophysiology of Idiopathic Hypersomnia

science phd research sleep md symptoms burden diagnosis dysfunction rem pathophysiology ih idiopathic differential diagnosis jazz pharmaceuticals hypersomnia gabaergic

Play Episode Listen Later Aug 17, 2023 14:40

While the pathophysiology of idiopathic hypersomnia is unknown, emerging science suggests that nighttime sleep dysfunction may contribute to daytime sleepiness in patients with idiopathic hypersomnia. A systematic review and meta-analysis that included 10 studies found that, on average, several sleep architecture hallmarks were different in patients with idiopathic hypersomnia relative to controls. Total sleep time and percent of REM sleep were increased in patients with idiopathic hypersomnia compared with controls. Sleep-onset latency and percent of slow-wave sleep were decreased in patients with idiopathic hypersomnia compared with controls. Sleep efficiency and REM latency were similar between patients with IH and controls. In addition to nighttime sleep dysfunction, other physiological changes have been observed in some patients with idiopathic hypersomnia and theorized as possible contributors to its pathophysiology including: Dysfunction of the GABAergic system Autonomic system dysfunction Altered functional or regional connectivity in the brain Circadian system dysfunction Dysfunction of energy metabolism This episode is produced by Sleep Review and is episode 5 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information. In episode 5, listen as Sleep Review's Sree Roy and neurologist-sleep specialist Isabelle Arnulf, MD, PhD, discuss: Science doesn't fully understand the pathophysiology of idiopathic hypersomnia. Research has revealed potential clues, however. For example, idiopathic hypersomnia is associated with changes in sleep staging and architecture. What does emerging science suggest are differences in nighttime sleep? How might the arousal index differ in idiopathic hypersomnia versus in people without it, and why might that matter? In addition to nighttime sleep dysfunction, other physiological changes have been observed in some patients with idiopathic hypersomnia and theorized as possible contributors to its pathophysiology. What is the GABAergic system and its possible role? What are some emerging findings surrounding idiopathic hypersomnia and autonomic system dysfunction? What is the evidence that supports the idea of altered functional or regional connectivity in the brain in people with idiopathic hypersomnia? There were fascinating studies done on skin fibroblasts, suggesting that circadian period length may be different in people with idiopathic hypersomnia versus in people without it. What role might circadian rhythm dysfunction have in idiopathic hypersomnia? What has science discovered about the possible role of dysfunction of energy metabolism in idiopathic hypersomnia? What further research would you like to see conducted on the pathophysiology of idiopathic hypersomnia? Listen to Episode 1: Symptoms of Idiopathic HypersomniaListen to Episode 2: Diagnosis of Idiopathic HypersomniaListen to Episode 3: Differential Diagnosis of Idiopathic HypersomniaListen to Episode 4: Burden of Idiopathic Hypersomnia

The Woman Who Couldn't Wake Up: Quinn Eastman on Hypersomnia and the science of sleepiness

Keen On Democracy

Play Episode Listen Later Aug 16, 2023 21:57

EPISODE 1653: In this KEEN ON show, Andrew talks to Quinn Eastman, author of THE WOMAN WHO COULDN'T WAKE UP, about idiopathic hypersomnia and the science of sleepiness Quinn Eastman is a technical editor at Emory University School of Medicine. He was trained as a biochemist, receiving a PhD from Yale University, and has worked as a journalist, covering local government and environmental issues as well as sleep research. Named as one of the "100 most connected men" by GQ magazine, Andrew Keen is amongst the world's best known broadcasters and commentators. In addition to presenting KEEN ON, he is the host of the long-running How To Fix Democracy show. He is also the author of four prescient books about digital technology: CULT OF THE AMATEUR, DIGITAL VERTIGO, THE INTERNET IS NOT THE ANSWER and HOW TO FIX THE FUTURE. Andrew lives in San Francisco, is married to Cassandra Knight, Google's VP of Litigation & Discovery, and has two grown children. Learn more about your ad choices. Visit megaphone.fm/adchoices

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Burden of Idiopathic Hypersomnia

Play Episode Listen Later Aug 10, 2023 10:31

People with idiopathic hypersomnia face a significant disease burden. Idiopathic hypersomnia is associated with challenges that impact daily living activities, such as limitations at school, work, interpersonal relationships, and social activities. Various impairments include Impacts on attention and cognition, which can be characterized as “brain fog”The burden of memory problems and a feeling of the mind going blank or making a mistake in a habitual activityPublic health and safety are also impacted, as more severe causes of sleepiness can be cause for accidents. Management strategies may not address the underlying sleep dysfunction associated, resulting in suboptimal symptom management. Patient survey and registry data suggest patients continue to experience symptoms of idiopathic hypersomnia and residual disease burden. This episode is produced by Sleep Review and is episode 4 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information. In episode 4, listen as Sleep Review's Sree Roy and pulmonologist-sleep specialist Richard K. Bogan, MD, discuss: What are some limits that people with idiopathic hypersomnia can experience in their daily living activities?How do people with idiopathic hypersomnia commonly describe "brain fog," and what are some of the real-life consequences it?How does prolonged sleep inertia place a burden on the people with idiopathic hypersomnia who experience this symptom?What do you see as the burden of idiopathic hypersomnia on public health and safety?Beyond medications, how is idiopathic hypersomnia typically managed to control for symptoms as much as possible?How do you determine when therapy for idiopathic hypersomnia has been optimized, and what symptoms may remain at this point?

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Burden of Idiopathic Hypersomnia

Play Episode Listen Later Aug 10, 2023 10:31

People with idiopathic hypersomnia face a significant disease burden. Idiopathic hypersomnia is associated with challenges that impact daily living activities, such as limitations at school, work, interpersonal relationships, and social activities. Various impairments include Impacts on attention and cognition, which can be characterized as “brain fog” The burden of memory problems and a feeling of the mind going blank or making a mistake in a habitual activity Public health and safety are also impacted, as more severe causes of sleepiness can be cause for accidents. Management strategies may not address the underlying sleep dysfunction associated, resulting in suboptimal symptom management. Patient survey and registry data suggest patients continue to experience symptoms of idiopathic hypersomnia and residual disease burden. This episode is produced by Sleep Review and is episode 4 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information. In episode 4, listen as Sleep Review's Sree Roy and pulmonologist-sleep specialist Richard K. Bogan, MD, discuss: What are some limits that people with idiopathic hypersomnia can experience in their daily living activities? How do people with idiopathic hypersomnia commonly describe "brain fog," and what are some of the real-life consequences it? How does prolonged sleep inertia place a burden on the people with idiopathic hypersomnia who experience this symptom? What do you see as the burden of idiopathic hypersomnia on public health and safety? Beyond medications, how is idiopathic hypersomnia typically managed to control for symptoms as much as possible? How do you determine when therapy for idiopathic hypersomnia has been optimized, and what symptoms may remain at this point?

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Differential Diagnosis of Idiopathic Hypersomnia

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Play Episode Listen Later Aug 3, 2023 15:33

The differential diagnosis of idiopathic hypersomnia is challenging for several reasons. Its hallmark symptom, excessive daytime sleepiness, is a common symptom of many disorders, and ts ancillary symptoms also overlap with other disorders. A lack of validated biomarkers adds to the challenge. Assessing for key symptoms and medical history is a first step to help identify patients presenting with excessive daytime sleepiness who may have idiopathic hypersomnia. From there, there are several symptoms that can differentiate the diagnosis of idiopathic hypersomnia from other disorders such as sleep apnea or narcolepsy. These include:Sleep inertia: sleep inertia is common in patients with idiopathic hypersomnia but can also be reported by individuals with mood disordersPatients with idiopathic hypersomnia often find naps to be long and unrefreshing, while patients with narcolepsy generally find short naps to be restorativeIf a patient has prolonged nighttime sleep, long sleeper syndrome should be considered; in contrast to patients with idiopathic hypersomnia, long sleepers feel refreshed and do not have daytime sleepiness and difficulty awakening if they are allowed to sleep as long as they needCognitive complaints, often described as "brain fog" are common symptoms of idiopathic hypersomnia but also can occur in patients with various sleep-wake disorders (including narcolepsy type 1 and insufficient sleep syndrome)This episode is produced by Sleep Review and is episode 3 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information. In episode 3, listen as Sleep Review's Sree Roy and neurologist-sleep specialist Yves Dauvilliers, MD, PhD, discuss:Idiopathic hypersomnia can be particularly challenging to diagnose because of its lack of specific biomarkers, as well as its symptoms resembling those of other disorders. How do you differentiate idiopathic hypersomnia from hypersomnias of a specific cause, such as narcolepsy type 1 and type 2, insufficient sleep syndrome, or hypersomnia due to a neurodegenerative disease?A minority of people simply need to sleep longer than most, even 10 hours or more, to feel refreshed. How do you determine if that applies to a given person, who may not have a sleep disorder at all?How do you differentiate idiopathic hypersomnia from hypersomnia comorbid to psychiatric disorders, such as prolonged sleep time tied to depression?At what point in ruling out other disorders should objective sleep testing, such as polysomnography and multiple sleep latency testing, be done?Why is idiopathic hypersomnia sometimes confused with sleep-breathing disorders? When would you recommend a CPAP trial to address possible apneas, hypopneas, or respiratory-event related arousals?How do you distinguish chronic fatigue syndrome from idiopathic hypersomnia?Listen to Episode 1: Symptoms of Idiopathic Hypersomnia Listen to Episode 2: Diagnosis of Idiopathic Hypersomnia

Differential Diagnosis of Idiopathic Hypersomnia

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Play Episode Listen Later Aug 3, 2023 15:33

The differential diagnosis of idiopathic hypersomnia is challenging for several reasons. Its hallmark symptom, excessive daytime sleepiness, is a common symptom of many disorders, and ts ancillary symptoms also overlap with other disorders. A lack of validated biomarkers adds to the challenge. Assessing for key symptoms and medical history is a first step to help identify patients presenting with excessive daytime sleepiness who may have idiopathic hypersomnia. From there, there are several symptoms that can differentiate the diagnosis of idiopathic hypersomnia from other disorders such as sleep apnea or narcolepsy. These include:Sleep inertia: sleep inertia is common in patients with idiopathic hypersomnia but can also be reported by individuals with mood disordersPatients with idiopathic hypersomnia often find naps to be long and unrefreshing, while patients with narcolepsy generally find short naps to be restorativeIf a patient has prolonged nighttime sleep, long sleeper syndrome should be considered; in contrast to patients with idiopathic hypersomnia, long sleepers feel refreshed and do not have daytime sleepiness and difficulty awakening if they are allowed to sleep as long as they needCognitive complaints, often described as "brain fog" are common symptoms of idiopathic hypersomnia but also can occur in patients with various sleep-wake disorders (including narcolepsy type 1 and insufficient sleep syndrome)This episode is produced by Sleep Review and is episode 3 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information. In episode 3, listen as Sleep Review's Sree Roy and neurologist-sleep specialist Yves Dauvilliers, MD, PhD, discuss:Idiopathic hypersomnia can be particularly challenging to diagnose because of its lack of specific biomarkers, as well as its symptoms resembling those of other disorders. How do you differentiate idiopathic hypersomnia from hypersomnias of a specific cause, such as narcolepsy type 1 and type 2, insufficient sleep syndrome, or hypersomnia due to a neurodegenerative disease?A minority of people simply need to sleep longer than most, even 10 hours or more, to feel refreshed. How do you determine if that applies to a given person, who may not have a sleep disorder at all?How do you differentiate idiopathic hypersomnia from hypersomnia comorbid to psychiatric disorders, such as prolonged sleep time tied to depression?At what point in ruling out other disorders should objective sleep testing, such as polysomnography and multiple sleep latency testing, be done?Why is idiopathic hypersomnia sometimes confused with sleep-breathing disorders? When would you recommend a CPAP trial to address possible apneas, hypopneas, or respiratory-event related arousals?How do you distinguish chronic fatigue syndrome from idiopathic hypersomnia?Listen to Episode 1: Symptoms of Idiopathic Hypersomnia Listen to Episode 2: Diagnosis of Idiopathic Hypersomnia

Diagnosis of Idiopathic Hypersomnia

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Play Episode Listen Later Jul 27, 2023 10:29

The International Classification of Sleep Disorders, 3rd ed, lists the criteria needed for a diagnosis idiopathic hypersomnia.For a diagnosis of idiopathic hypersomnia, the following must be met:o excessive daytime sleepiness daily for at least 3 monthso cataplexy is not presento multiple sleep latency test (MSLT) shows 90%)o Long, unrefreshing naps (>1 hour)This episode is produced by Sleep Review. It is episode 2 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information.In episode 2, listen as Sleep Review's Sree Roy and neurologist-sleep specialist Margaret S. Blattner, MD, PhD discuss:o What are some barriers to diagnosing idiopathic hypersomnia?o Objective sleep testing is needed to diagnosis idiopathic hypersomnia. What polysomnography and multiple sleep latency test findings support a diagnosis of idiopathic hypersomnia?o What are some best practices for conducting a PSG and MSLT for a patient with suspected idiopathic hypersomnia?o What are some of the additional commonly seen supportive features of idiopathic hypersomnia?

Diagnosis of Idiopathic Hypersomnia

phd md diagnosis psg severe rem objective sleep disorders idiopathic international classification jazz pharmaceuticals hypersomnia outand

Play Episode Listen Later Jul 27, 2023 10:29

The International Classification of Sleep Disorders, 3rd ed, lists the criteria needed for a diagnosis idiopathic hypersomnia.For a diagnosis of idiopathic hypersomnia, the following must be met:o excessive daytime sleepiness daily for at least 3 monthso cataplexy is not presento multiple sleep latency test (MSLT) shows 90%)o Long, unrefreshing naps (>1 hour)This episode is produced by Sleep Review. It is episode 2 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information.In episode 2, listen as Sleep Review's Sree Roy and neurologist-sleep specialist Margaret S. Blattner, MD, PhD discuss:o What are some barriers to diagnosing idiopathic hypersomnia?o Objective sleep testing is needed to diagnosis idiopathic hypersomnia. What polysomnography and multiple sleep latency test findings support a diagnosis of idiopathic hypersomnia?o What are some best practices for conducting a PSG and MSLT for a patient with suspected idiopathic hypersomnia?o What are some of the additional commonly seen supportive features of idiopathic hypersomnia?

Symptoms of Idiopathic Hypersomnia

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Play Episode Listen Later Jul 20, 2023 15:47

Excessive daytime sleepiness is an essential feature of idiopathic hypersomnia, but other key symptoms and aspects of the medical history are crucial when evaluating patients who present with excessive daytime sleepiness. Patients with idiopathic hypersomnia commonly report the following symptoms in addition to excessive daytime sleepiness: severe and prolonged sleep inertia, long and unrefreshing naps, prolonged sleep time, and cognitive dysfunction.Knowing the key symptoms and utilizing sleep testing can increase a healthcare professional's confidence in his/her diagnosis of idiopathic hypersomnia.The Idiopathic Hypersomnia Severity Scale is a 14-item questionnaire that is a clinical tool designed specifically to measure patients' idiopathic hypersomnia symptoms and provide a touchpoint that might be useful for patient identification, follow-up visits, and idiopathic hypersomnia management.This episode is produced by Sleep Review. It is episode 1 of a 5-part series sponsored by Jazz Pharmaceuticals. Visit Jazzpharma.com and SleepCountsHCP.com for more information.In episode 1, listen as Sleep Review's Sree Roy and sleep specialist Logan Schneider, MD, discuss:The symptom of idiopathic hypersomnia that people are most familiar with is excessive daytime sleepiness. Will you define and briefly explain this core symptom?But excessive daytime sleepiness is not the only symptom typically reported by people with idiopathic hypersomnia. Prolonged sleep time is another common symptom. What can this mean over the course of a 24-hour day?Sleep inertia, that feeling of difficulty waking up, can happen to all of us. How can sleep inertia differ in people with idiopathic hypersomnia versus in those without it?Are naps generally restorative for people with idiopathic hypersomnia? Does length matter?What ancillary cognitive symptoms are commonly reported with idiopathic hypersomnia?In 2019, the Idiopathic Hypersomnia Severity Scale was developed to measure the severity, frequency, and functional impact of the key symptoms of excessive daytime sleepiness, prolonged nighttime sleep, and sleep inertia. What do you think is the clinical utility of this questionnaire?To dive even deeper:https://sleepreviewmag.com/sleep-disorders/hypersomnias/idiopathic-hypersomniaTrotti LM. Idiopathic hypersomnia. Sleep Med Clin. 2017;12(3):331-44.Dauvilliers Y. Idiopathic hypersomnia severity scale. 2018.Arnulf I, Leu-Semenescu S, Dodet P. Precision medicine for idiopathic hypersomnia. Sleep Med Clin. 2019;14(3):333-50.Vernet C, Leu-Semenescu S, Buzare MA, Arnulf I. Subjective symptoms in idiopathic hypersomnia: beyond excessive sleepiness. J Sleep Res. 2010;19(4):525-34.Dauvilliers Y, Evangelista E, Barateau L, et al. Measurement of symptoms in idiopathic hypersomnia: The Idiopathic Hypersomnia Severity Scale. Neurology. 2019;92(15):e1754-62.Rassu AL, Evangelista E, Barateau L, et al. Idiopathic Hypersomnia Severity Scale to better quantify symptoms severity and their consequences in idiopathic hypersomnia. J Clin Sleep Med. 2022;18(2):617-29.

Symptoms of Idiopathic Hypersomnia