POPULARITY
Categories
The benefits of PilatesWhat does it mean that certain brands of nattokinase are "free of K2"?Should I avoid soy products due to my history of breast cancer?How can I choose the best fish oil? Is there a certain dose you recommend?Is there any other supplement I can take besides 5-HTP for mood? What about SAMe?Is there any relief for my friend with ulcerative colitis?
The benefits of kimchi for detoxing microplasticsWhat do you recommend my husband take to recover from Bell's Palsy? Follow-up on coronary artery inflammation question
Sleep, Growth Hormone, and Autophagy: How Rest, Diet, and Fasting Support Metabolic Health and Longevity: Nutritionist Leyla Muedin discusses how deep, early non-REM sleep boosts growth hormone for muscle, bone, fat burning, and metabolic health, and reviews a Cell study in which UC Berkeley researchers mapped hypothalamic circuits and feedback through the locus coeruleus showing a tight balance between sleep, growth hormone release, and wakefulness, with implications for metabolic disease and neurodegeneration. She connects poor sleep to higher blood sugar, insulin, and cortisol, which can suppress growth hormone, and advises avoiding sweet post-workout foods (e.g., smoothies, bananas, fruit yogurt) that stimulate insulin and blunt growth hormone, recommending protein and fat instead. She then explains autophagy and mitophagy as cellular cleanup processes linked to longevity, noting autophagy peaks after 12 hours of fasting, highlighting roles in mitochondrial quality control, immunity, and neurodegenerative disease, and mentions interventions such as fasting, exercise, ketogenic diets, and investigational inducers like rapamycin and urolithin A.
By Doug Green “You're really selling expertise, judgment and an understanding of the customer's goals.” In this Technology Reseller News podcast, Devon Rutherford, Sales Solution Manager at Leaseweb, discusses why MSPs should rethink infrastructure sales around customer workloads rather than around a preferred vendor or platform. Leaseweb is an infrastructure-as-a-service provider offering colocation, private and public cloud, dedicated servers, security services and other infrastructure solutions. Rutherford says the MSP market has changed because customers can now buy cloud and infrastructure services directly from a wide range of providers. That means the real value of the MSP increasingly lies in expertise. “The customer can go buy the infrastructure,” Rutherford says. “What they need from the MSP is help understanding where the workload should actually live.” That may mean avoiding the temptation to place every workload onto the platform that offers the best margin or partner incentive. Different workloads have different requirements. An AI inference workload may need to be close to the end user. A stable application may run more economically on bare metal. Other workloads may need public cloud elasticity, object storage, CDN services or specialized compliance controls. That naturally leads toward hybrid infrastructure. Rutherford says the MSP's role is increasingly to understand the business objective, regulatory requirements, performance needs and economics of each workload and then assemble the appropriate infrastructure. That consultative approach can also create recurring revenue. Instead of treating infrastructure placement as a one-time project, MSPs can establish regular reviews with customers to determine whether workloads are still in the right environment as requirements change. “Infrastructure is highly commoditized,” Rutherford says. “Consultative expertise isn't.” For MSPs planning for the year ahead, his recommendation is to follow the workload rather than the vendor. That can strengthen customer trust while positioning the MSP as the ongoing adviser responsible for making the different pieces of a hybrid environment work together. Leaseweb supports that approach with infrastructure options across bare metal, cloud, storage and colocation, along with engineers who can work directly with partners and customers on architecture decisions. Visit Leaseweb.com to learn more.
Michelle Routhenstein, MS, RD, CDCES, CDN, is a preventive cardiology dietitian and founder of Entirely Nourished, a virtual nutrition practice focused on helping people improve their heart health through personalized, evidence-based nutrition. With more than 14 years of experience in cardiovascular nutrition, Michelle helps clients address cholesterol, blood pressure, inflammation, blood sugar, insulin resistance and other cardiometabolic risk factors. Her work focuses on preventing and managing conditions including heart disease, heart failure, atherosclerosis and atrial fibrillation while translating complex science into practical, sustainable strategies. Michelle earned her Bachelor's and Master's degrees in Clinical Nutrition from New York University and previously worked in New York City hospitals managing complex medical cases. She serves on the Forbes Health Advisory Board and the Medical Advisory Committee for the National Menopause Foundation and is the author of The Truly Easy Heart-Healthy Cookbook and Simple Meal Solutions for High Blood Pressure. Her expertise has been featured in Forbes Health, Fox News, Women's Health, Prevention, GLAMOUR, Good Housekeeping and other major outlets. Today on the show, we discuss why the ketogenic diet may accelerate plaque formation, why ApoB and other overlooked blood markers matter for heart disease risk, how blood pressure and sodium can affect your arteries, the truth about fiber caffeine alcohol and energy drinks, why exercise alone cannot fully protect your heart and how genetics supplements medications and nutrition all play a role in preventing cardiovascular disease and much more. Visit www.entirelynourished.com to learn more. Learn more about your ad choices. Visit megaphone.fm/adchoices
When people go on GLP-1 medications, part of the treatment plan is to encourage them to exercise. But what about all the already active–even athletic–women who are layering them onto serious training? That's less clear…and far less researched. Performance nutritionist Heidi Skolnik, author of the new book Your GLP-1 Game Plan, returns to break down how these medications really work, the side effects you may be prepared for (as well as some important ones nobody warns you about), and how to protect your muscles and bones and build a fueling strategy that actually works. We also get into hydration, supplements, eating-disorder red flags, and whether serious performance and GLP-1s can coexist. This one is filled with real talk, no shame, and no easy answers.Considered a thought leader in nutrition, Heidi Skolnik, MS, CDN, is a NY Times best-selling co author, part of The Women's Sports Medicine Center at Hospital for Special Surgery in NYC and oversees the Performance Nutrition program at The Juilliard School. She started the Performance Nutrition program at the School of American Ballet and worked as team nutritionist for the WNBA NY Liberty, NBA Knicks, NFL Giants and MLB Mets. Heidi sits on the medical advisory board of the National Menopause Foundation and The NYRR (New York Road Runners) and sat on the board of The National Bone Health and Osteoporosis Foundation for 10 years. Heidi has earned two Master's degrees (exercise physiology and human nutrition) and is a Fellow with the American College of Sports Medicine. Heidi began her career in corporate fitness and wellness at Morgan Stanley for the Sports Training Institute. As a realist, Heidi believes M&M's can fit into a healthy eating style along with red peppers, red meat, broccoli, and fresh fruit. You can learn more about her work and get the book at www.heidiskolnik.comhttps://livefeisty.com/training/Courses and Coaching: https://livefeisty.com/courses/Sign up for our FREE Feisty 40+ newsletter: https://livefeisty.com/newsletters/feisty-40/Follow Us on Instagram:Feisty Menopause: @feistymenopauseHit Play Not Pause Facebook Group: https://www.facebook.com/groups/807943973376099Support our Partners:Hettas: Shop Hettas at https://alnk.to/h6KsEBr Midi Health: You Deserve to Feel Great. Book your virtual visit today at https://www.joinmidi.com/Previnex: Get 15% off your order with code HITPLAY at https://www.previnex.com/ Wahoo: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdr
Concurrent Training for Healthy Aging and the Overlooked B12 Risk of Metformin: Nutritionist Leyla Muedin discusses how concurrent training—combining cardio and strength work—supports healthy aging by building endurance, preserving muscle, and maintaining independence and “healthspan.” She explains that aerobic exercise improves cardiorespiratory efficiency while resistance training preserves lean tissue and functional strength, and offers practical scheduling tips: place strength sessions on two non-consecutive days, add moderate cardio around them, separate hard sessions, prioritize recovery with rest days, sleep, and adequate protein, and avoid pairing heavy lifting with hard endurance work if explosive power is important. She then summarizes evidence that clinicians often fail to check vitamin B12 levels in diabetic patients on long-term metformin, despite guidelines; metformin can impair B12 absorption, leading to deficiency, anemia, and potentially reversible neuropathy, with higher risk in the elderly, high-dose users, vegans, and PPI users. She urges proactive B12 monitoring and supplementation, such as a multivitamin with at least 100 mcg B12.
Autonomous Artificial Intelligence (AI) and the future of medicineAre there any alternative ways to lower my blood pressure other than taking prescription medication?
As soon as I take my blood pressure meds, I get tired and lack energy for the rest of the day. What gives?I'm 77 and have Sjögren's syndrome. Can I take carnitine? How much should I take?Are there cardiac side effects to berberine? Both my husband and I take it for blood sugar.What types of protein are most helpful for osteoporosis and weight gain?The coronary artery inflammation controversy
PHP Podcast – September 17, 2026 Hosts: Joe Ferguson, Sara Golemon & John Congdon The September issue shipped 13 days early, a blue elephant named Eric raised eyebrows, PHP 8.6 is racing GTA 6 to a November launch, and a CDN bug taught us all a lesson about cache keys. Also: a lot of World of Warcraft. The September Issue Ships Early (and the Blue Elephant Situation) The September issue of PHP Architect went live on the day of recording, roughly 13 days ahead of the usual schedule. Joe credited a flood of feature articles from the community, columnists turning work in early, and editor Jackie’s first pass for keeping the whole company-wide review process ahead of the game. If you’d like to write for the magazine, they pay real cash in American denominations — just head to phparch.com. Attention quickly turned to the cover, which featured a distinctly blue elephant that the crew agreed had strong “Eric” energy. It came out that this was Jackie’s first attempt at managing the AI-generated cover art, which sparked plenty of teasing about who exactly the human-in-the-loop was. The team also teased upcoming pet shirts and cat socks for the swag store. PHP Foundation Community Hour Launches Joe highlighted the brand-new PHP Foundation Community Hour, a podcast produced by PHP Architect and recorded live on the same network as this show. It has its own dedicated RSS feed alongside the usual channels — find it under the podcasts section on the website. The first episode featured Elizabeth Barron interviewing Matt Stauffer about his blog post on contributing to PHP. Sara praised Matt as a great addition to the Foundation Board, and the crew noted his deep experience getting people to contribute to open source projects, plus his well-known Laravel: Up & Running book. The next episode lands next month with another guest on the theme of contributing to PHP. The PHP Documentary and 8.6 vs. GTA 6 Sara shared that she finally recorded her interview for the upcoming PHP documentary — filmmaker Jeremy came right to her apartment in Lisbon to shoot it. She’s since seen an hour-long cut and teased that it covers a bit of PHP history, the people involved, and the good and bad choices made along the way. Release timing is still fuzzy, somewhere between one and three months out. On the release side, Holly noted developer beta 3 is out with the RC approaching, at which point she’ll start pushing her RFCs out for discussion and voting. Joe revealed the general release date: Thursday, November 19th, PHP 8.6.0 — the very same day a small indie title called Grand Theft Auto 6 arrives. The last of the 8.6 deprecations only just merged, so even beta 3 didn’t have everything yet. The CDN Bug That Cached the Wrong Homepage Joe walked through a genuinely wild bug on php.net’s new CDN. Bot traffic throwing URL-encoded sequences like %2F, %5C, and %3F caused the CDN to normalize those junk paths down to a single forward slash — and then use that as the cache key, overwriting the homepage cache with 301s, 302s, and 404s. The effect was localized to whichever CDN nodes the bot swarm happened to hit, which made it maddening to reproduce. Sara pointed out the CDN was actually doing something reasonable in normalizing the path; the real bug was serving a different page than the one you’d get requesting the root. Joe praised the provider’s support team, who confirmed the issue, escalated it to engineering, and validated his mitigation of disabling caching for those status codes. The conversation broadened into how AI crawlers and more sophisticated, high-unique-IP bot traffic are surfacing long-dormant bugs — and the uncomfortable centralization that comes from everyone hiding behind the same few CDN providers. Foldables, Front-End, and the WoW Detour Holly kicked off a discussion about Apple’s new foldable device and what it means for front-end design. Her core gripe: mobile screens already lose vertical space to status bars, nav bars, ad bars, and tab bars, so a wider aspect ratio can make things worse. She praised Apple for moving native app navigation off to the side to reclaim vertical space, but noted that does nothing for web pages — which she argues most responsive designs still don’t handle well, especially on 16:9 Android tablets. Joe weighed in from a consumer angle, worrying about hinge durability on $2,000 foldables and whether they’ll last the three-to-four years he now expects from a phone. Somewhere in between, the show detoured hard into gaming — WoW Classic “Forever,” the November 4th launch, tank builds, and even the naming of shadow priests — before circling back to remind everyone you can, in fact, write MMOs in PHP. Links from the show: PHP Architect — September issue now live PHP Tech 2027 — Early bird tickets (April 27–29, 2027, Chicago) PHP Tech 2027 CFP — Open until October 31 First PHP Community Hour Podcast Join the live show on Discord Host: Joe Ferguson Mastodon: @joepferguson@phpc.social PHPArch.me: @svpernova09 Sara Golemon Mastodon: @pollita@phpc.social Holly Schilling Mastodon: @TheCodeLorax@tech.lgbt Streams: Youtube Channel Twitch Connect & Hire PHP Architect Website Twitter/X Mastodon Hire PHP Developers Looking to hire PHP developers? Email support@phparch.com – Joe and the team are available for consulting, infrastructure work, Ansible playbooks, and code review. Partner This podcast is made a little better thanks to our partners OurCVEs Your security posture, on autopilot with OurCVEs CodeRabbit Cut code review time & bugs in half instantly with CodeRabbit. PHP Architect Consulting Your PHP codebase deserves a partner, not a contractor PHP Architect provides long-term technical partnerships for organizations that need senior-level PHP expertise that you can depend on. https://www.phparch.com/consulting/ Music Provided by Epidemic Sound https://www.epidemicsound.com/ Join Us Live Next Week Youtube Channel Got feedback? Join us on Discord at discord.phparch.com The post The PHP Podcast 2026.09.17 appeared first on PHP Architect.
Nueva temporada, mismos protagonistas Empieza la temporada once de potencia.pro (capítulo 335, con rima incluida) tras un verano sin grabar juntos. Miguel Ángel Terrón y Mariano Pérez vuelven a hablar de lo de siempre: cómo mejorar tu negocio con WordPress e IA… y de «cozas», que son otras cosas. Novedad de temporada: la página principal de potencia.pro está rediseñada enterita (bueno, enterita salvo alguna página suelta como la de la gaceta, que sigue igual que siempre). Ahí se explica todo lo que hace el proyecto, los plugins disponibles y demás. Y si quieres estar al día: El grupo de Telegram: potencia.pro/telegram La gaceta/newsletter, cuya escaleta ahora la escribe la IA: potencia.pro/gaceta Un saludo cariñoso de paso a los compañeros de otros podcasts de WordPress en español, entre ellos Pablo y Ana de Un billete a chattanooga, y a Nahuai Badiola y Esther Solà. Que aunque por ahí se diga que son el único podcast de WordPress en español, basta buscar en Google para ver que hay tres o cuatro. Nosotros, del montón, tan felices. El culebrón: echan a Matt y vuelve dos días después La gran noticia post-verano: destituyeron a Matt Mullenweg como CEO de Automattic, la empresa detrás de WordPress.com, WooCommerce y compañía. Lo curioso es lo poco que se sabe, porque los únicos que estaban dentro no han dado declaraciones. Lo que ha trascendido: El consejo de administración (unas 7-8 personas) votó darle a Matt un permiso retribuido, una especie de baja pagada. Todos votaron a favor menos uno. Pusieron al director financiero como CEO en funciones. Matt asegura que se lo comunicaron 50 minutos antes de empezar la reunión, y pidió tiempo para hablar con sus abogados. Dos días después, algo pasó: Matt volvió a ser CEO y se marcharon todos los que habían votado a favor. No como venganza —insiste— sino por pérdida de confianza. Después publicó un anuncio buscando administradores de sistemas para, según dijo, «sacar sus cosas del servidor de Automattic» (probablemente su web personal y lo relacionado con .org). Terreno de pura especulación. Mary Hubbard, responsable de WordPress.org, comentó en el Slack que sus responsabilidades allí seguían intactas aunque Matt no fuera CEO, y que estaba encantada de que volviera. Otra pista interesante: se anunció el equipo que sacará WordPress 7.2 (previsto para mediados/finales de noviembre), y Matt figura como líder de la distribución, algo que no hacía desde hacía tiempo. Ha vuelto con energía renovada. Cloudflare con WordPress: lo gratis y lo de pago El bloque técnico va sobre Cloudflare, del que confesamos estar enamorados. Está muy de moda últimamente, en parte porque cada fin de semana la Liga bloquea rangos de IP para perseguir las retransmisiones piratas de fútbol, y a veces cae por medio alguna web legítima que comparte IP con contenido pirata. Un matiz importante: si tu web comparte IP con piratas no significa que seas pirata, y la Liga solo debería bloquear IPs concretas señaladas, no todas. Aun así, es un tema polémico. Más allá de la polémica, Cloudflare es una maravilla. Es un CDN (Content Delivery Network): si tu web está en un servidor de París, Londres o Madrid, el CDN sirve el contenido desde el nodo más cercano al usuario. Muy útil para audiencias internacionales; menos relevante si el 90% de tus clientes están en España. La parte gratis (más de la que parece) DNS más rápido que cualquier otro, incluso el de Google. Mejora el TTFB (Time To First Byte). Seguridad: protección frente a ataques DoS (denegación de servicio) y el famoso botón «I’m Under Attack». Filtrado de tráfico malicioso. Brotli: compresor que reduce el peso de las imágenes más que la compresión tradicional. HTTP/2 y HTTP/3: más estables y con mejor rendimiento de caché. Early Hints: técnica para empezar a cargar recursos importantes antes de que el servidor termine de generar la página. La parte de pago: APO Por unos 5 € al mes, el plugin de Cloudflare para WordPress activa APO (Automatic Platform Optimization): Cloudflare cachea tu web y la sirve como si fuera estática desde sus servidores, sin ir a tu alojamiento ni golpear la base de datos. Casi tan barato como la suscripción de potencia.pro (menos de 2 € al mes). ¿Problemas posibles? Prácticamente ninguno si la web está bien configurada y no tiene contenido mixto (recursos servidos por HTTP en vez de HTTPS). A estas alturas, eso no debería ser un problema para nadie. Plugin del día: Updater from Drive Esta vez el plugin es de cosecha propia: Updater from Drive («actualizador desde Drive»). Resuelve un dolor real cuando gestionas muchos clientes: Tienes plugins personalizados o con licencia que no quieres meter directamente en cada web del cliente. Aun así quieres que se actualicen automáticamente. Cómo funciona: Conectas el plugin con Google Drive mediante su API. Le indicas una carpeta donde guardas todos los plugins que deben actualizarse. Cada 24 horas (o al pulsar el botón Check Now), revisa la carpeta y actualiza los plugins que hayan cambiado, como si fuera el repositorio de WordPress.org pero con tus plugins. Admite excepciones y reglas: si no identifica un plugin, puedes decirle qué fichero .zip corresponde a cada uno. Ideal si gestionas 70 webs de clientes y actualizar todo a mano es un suplicio (y MainWP no siempre va fino). El plugin estará disponible en la sección de descargas para que la gente lo trastee. Además, se prepara un plugin específico para los suscriptores de potencia.pro que permitirá auto-actualizar los plugins descargados desde la plataforma automáticamente, como una actualización más de WordPress. Y con esto cerramos el primer capítulo de la temporada once. Nos vemos la semana que viene. 🤖 El contenido de este post ha sido generado automáticamente con inteligencia artificial a partir de la transcripción del audio. Puede contener errores o imprecisiones. 🎙️ Publicado con VozCaster, el bot de Telegram que convierte tu voz en un episodio de podcast publicado. Pruébalo gratis. ¿Te ha gustado el episodio? Si quieres que sigamos experimentando con bots, protocolos y empanadillas polacas, no olvides suscribirte y dejarnos tu valoración. ¡Nos escuchamos en el próximo capítulo! Métodos de contacto Enviadnos vuestras preguntas al grupo de Telegram. Apuntaos al canal de Youtube del podcast https://www.youtube.com/potenciapro Si nos queréis decir algo directamente lo podéis hacer a @potenciapro , @materron, @mpc, o en el grupo de Telegram Y si eres muy muy muy fan del podcast Echa un vistazo a cómo nos puedes ayudar en https://potencia.pro/se-prosperoso/
Show DescriptionWe're joined by Thomas Steiner from Google to discuss his proposal for cross-origin storage, a new web API designed to bring back safe, cross-site resource sharing. We explore why the old shared-CDN caching model collapsed due to privacy and fingerprinting risks, and how this could solve those issues while avoiding those same pitfalls. Listen on WebsiteWatch on YouTubeGuestsThomas SteinerGuest's Main URL • Guest's SocialDeveloper Relations Engineer at Google, focused on the Web and Project Fugu. Links David Bushell daverupert.com 633: Thomas Steiner on AI in Chrome and the Web Pervasive Resources Intent to ship: Cache sharing for extremely-pervasive resources
Nutritionist Leyla Muedin answers a listener question about taking many supplements with oolong tea, explaining that tea tannins can interfere with vitamin and mineral absorption; because oolong is partially oxidized, its tannin level falls between green and black tea, so she recommends taking supplements with water and separating them from tea or coffee by at least an hour (ideally 1.5–2 hours). She then reviews research in Nature Communications from USC on how gut signals via the vagus nerve may influence which food experiences become memories: in rats, nutrient-rich foods increased acetylcholine signaling to the hippocampus, supporting memory for food location, while sweetness without calories did not. Over time, high-fat/high-sugar diets weakened this gut–hippocampus communication and memory performance, with implications for obesity, diabetes/prediabetes, and cognitive decline, and possible future vagus-nerve-based approaches.
Ken Armstrong, CEO of Westhaven Gold Corp. (TSX-V: WHN) (OTCQB: WTHVF) (FRA: 1W5), joins us for a corporate update on the management and board refresh from 2024-2025, the transformational strategic earn-in agreement with Dundee Corp initially announced in December of 2025, and the ongoing 50,000m infill and expansion exploration program at the Shovelnose Project in British Columbia. We also discuss the development work on tap along the pathway towards a Pre-Feasibility Study and then Feasibility study. Westhaven is a gold and silver focused exploration and development company targeting low sulphidation, high-grade, epithermal style gold and silver mineralization within the Spences Bridge Gold Belt in southern British Columbia. Westhaven controls ~60,263 hectares within four properties spread along this underexplored belt. The Shovelnose gold and silver project is the most advanced property, with a 2025 updated Preliminary Economic Assessment that validates the project's potential as a robust, low cost and high margin 11-year underground gold mining opportunity with average annual life-of-mine production of 56,000 ounces gold and 313,000 ounces silver with a CDN$454 million after-tax net present value (at a 6% discount rate) and 43.2% IRR (base case parameters of US$2,400 per ounce gold, US$28 per ounce silver and CDN/US$ exchange rate of CDN$1.00=US$0.72).1 On February 23, 2026, Westhaven closed a strategic earn-in agreement with Dundee Corporation, whereby Dundee may earn up to a 60% interest in Westhaven's four Spences Bridge Gold Belt properties through up to CDN$85,000,000 in staged project expenditures. Under the first phase, Dundee has committed a minimum of CDN$30,000,000, inclusive of a fully funded 50,000m drill program and pre-feasibility work at Shovelnose. The agreement allows for the accelerated exploration and evaluation of one of Canada's most compelling, undeveloped, high-margin gold and silver assets. Assay results that have been coming in from the ongoing 35,000m four-rig resource infill drilling program at the South Zone gold and silver deposit on the Shovelnose gold property, continue to show excellent continuity of mineralization in each of Vein Zones 1, 2 and 3. A fifth rig has been added for the ongoing 15,000m exploration drill program that will run through December. Click here to follow the latest news from Westhaven Gold If you have any question for Ken regarding Westhaven Gold, then please email those to us at Fleck@kereport.com or Shad@kereport.com. For more market commentary & interview summaries, subscribe to our Substack reports: The KE Report: https://kereport.substack.com/ Shad's resource market commentary: https://excelsiorprosperity.substack.com/ Investment disclaimer: This content is for informational and educational purposes only and does not constitute investment advice, an offer, or a solicitation to buy or sell any security. Investing in equities and commodities involves risk, including the possible loss of principal. Do your own research and consult a licensed financial advisor before making any investment decisions. Guests and hosts may own shares in companies mentioned.
How can I find an integrative pediatrician in the NYC or Weehawken/Hoboken area?Can the xylitol in my nasal spray have an adverse impact on heart health?I chronically use Vaseline on my lips. Is this a concern?My 25-year-old daughter was diagnosed with lipedema stage one. Any advice?I had an Apo B test and am confused at the results. Could you elucidate?
Ultra-processed foods' impact on postpartum depression/psychosisWhich should my sister take, Jardiance or Dapagliflozen? I had aortic valve repair. Can I safely take N101?I suffer with trigeminal neuralgia after recent extensive dental work. What do you advise?What would be the optimal total testosterone level for an 84 year old male?
Exercise, Recovery, Relaxation—and Muscle as the Key to Healthy Aging: Nutritionist Leyla Muedin discusses science-backed wellness trends that pair exercise with effective recovery and deliberate relaxation to support performance, resilience, and healthy aging, noting benefits such as fewer overuse injuries, better sleep, steadier energy, and improved adherence. She highlights relaxation practices (breathwork, meditation, gentle yoga, outdoor time, massage, consistent sleep routines) and encourages making recovery part of daily life, including creating home or community “wellness spaces” like pools for gentle movement and stress reduction. She emphasizes sustainable habits supported by tools like wearables and heart-rate variability tracking. The episode then frames muscle as a “longevity secret weapon,” explaining its roles in metabolism, glucose storage, insulin sensitivity, inflammation control, and joint stability, citing the PURE study on grip strength and mortality, warning about sarcopenia, and recommending strength training, higher and well-distributed protein intake with age due to anabolic resistance, plus adequate sleep and recovery.
How should I take N101 lozenges?Where can I find Propax with NT Factor? I prefer capsule or pill form.Why is the Salad and Salmon diet not mentioned? It's the best of both worlds in a whole-foods eating plan.My doctor wants me to take a statin, but I'm reluctant because of sensitivities and reactions to drugs.I've been told to avoid red meat and instead take an iron supplement, but it's causing constipationHow much magnesium should I take for my weight at 160 lbs?
Highlights from Dr. Hoffman's vacation.What can my friend take for burning mouth syndrome?I'm looking to build immunity. What are your thoughts on beta-glucans?I hike a lot and want to protect my knees. Would peptides like BPC-157 be of benefit?
Today we are talking about Drupal Performance, Rapid Development, and Drupal Canvas Maturity with our hosts. We'll also cover Microsoft 365 FullCalendar as our module of the week. For show notes visit: https://www.talkingDrupal.com/568 Topics Deprecating Module Theme Files Migrating Hooks to Classes Why This Change Matters Drupal Performance Gains Performance Audits and Lighthouse Automating Checks and Spreadsheet Rant AI Spreadsheet Cautionary Tale Privacy Concerns with AI Freelancer Pressure Rapid Change Reality Canvas Release Risks Community Support Needed AI For Documentation Canvas Production Readiness Canvas Architecture Debate AI For Voting Research LLM Bias And Sources Resources Rebrickable Webpagetest Lighthouse Tugboat Drupal canvas Guests Martin Anderson-Clutz - mandclu.com mandclu Hosts Nic Laflin - nLighteneddevelopment.com nicxvan John Picozzi - epam.com johnpicozzi Amber Matz - tugboatqa.com [amber himes matz](https://www.drupal.org/u/amber himes matz) MOTW Correspondent Martin Anderson-Clutz - mandclu.com mandclu Brief description: Have you ever wanted your users' own Outlook calendars to show up right alongside your Drupal content in a calendar view? There's a module for that. Module name/project name: Microsoft 365 FullCalendar Brief history How old: created just last month, August 19 2026, by fabianderijk of Finalist Versions available: 1.0.0, which works with Drupal 11 Maintainership Brand new — the first and only release is from last month, and the whole commit history is basically launch day Security coverage: brand new, so not yet Test coverage: yes, both unit tests and kernel tests Documentation: a genuinely thorough README — it walks through privacy, the config guard rails, and three different ways to customize event output Open issues: none yet, it's less than two weeks old Usage stats: Too new for a site count Module features and usage With this installed, it adds the signed-in user's Microsoft 365, or Outlook, calendar as an extra event source on a FullCalendar view — so their personal appointments sit right next to the Drupal content the view already renders It leans on the Microsoft 365 Connector module and its SSO submodule, plus the FullCalendar module. Each user must have signed in through Microsoft 365 SSO: anyone who hasn't just sees no events, which is a clean fallback It uses lazy loading, so it only fetches events in the date range the calendar is currently showing, not your whole calendar Privacy is baked in: anything marked private or confidential in Outlook is masked, so it shows up as just "Busy", with no title, location, or meeting link, unless the site builder deliberately turns masking off The response itself is per-user and marked private, no-store, so it never lands in a shared or CDN cache There's a clever server-side cache too: it stores the raw Graph response before masking, so a single fetch can serve several displays that each have different masking settings You get guard rails you can tune with Drush or an admin form: max events, max date range, cache lifetime, and a separate, shorter failure cache That failure cache is a nice touch — if there's no active Microsoft session, or Graph errors out, it caches the empty result briefly so a broken connection doesn't get re-polled on every single calendar click Under the hood it calls Graph's calendarView endpoint rather than /me/events, which means recurring meetings get expanded into their individual occurrences — exactly what a calendar grid needs Every event carries CSS classes for its status — busy, free, tentative, out-of-office, working elsewhere, cancelled — so you can style them however you want And if CSS isn't enough, there's a server-side alter hook and a JavaScript pre-build event for fully custom rendering. Nice detail: the hook is explicitly guarded so you can't use it to put back a title or location that masking just stripped out Clearly this will be more useful for edge cases, for example an intranet, but I think this is a really interesting example of the power of Drupal as an integration layer, or as some like to put it, the "glass" through which a user can interact with multiple systems
What if your website already supports post-quantum cryptography, but nobody inside your organization knows how, why, or which provider controls it? I speak with David Warburton, Director of F5 Labs Threat Research, about new F5 research examining post-quantum cryptography across the world's top one million websites. According to the research discussed in our conversation, 54% now support PQC. It is an encouraging sign that preparations for future quantum threats are entering mainstream infrastructure. That figure is also easy to misread. David explains that much of the adoption comes from cloud and CDN providers enabling hybrid post-quantum protection for their customers. A smaller business could therefore appear better prepared than a large enterprise simply because its provider activated the technology automatically. However, that customer may have little understanding of the chosen cipher, the protection applied elsewhere, or the dependencies created around a small number of technology companies. David says the adoption rate looks very different when major CDN providers are removed from the data. This raises an important question about whether businesses are developing their own post-quantum security capabilities or temporarily benefiting from decisions made on their behalf. We discuss why current deployments combine established cryptography with newer post-quantum algorithms. This hybrid approach protects compatibility while browsers, APIs, operational technology, IoT devices, and older enterprise systems catch up. It also carries performance costs through larger cryptographic material and increased network traffic. David argues that crypto agility matters because organizations need the ability to change algorithms, certificates, and encryption methods as threats develop. The conversation also moves beyond encrypted traffic. Harvest now, decrypt later attacks involve collecting sensitive information today so it can potentially be decrypted when capable quantum computers arrive. David believes authentication and digital identity could create an even greater concern. A quantum computer able to produce valid certificates could potentially impersonate trusted websites, signed software, devices, or firmware. Legacy infrastructure remains one of the largest barriers. F5 Labs found that roughly one in ten leading websites lacked TLS 1.3 support, preventing them from supporting current hybrid PQC connections. David also explains why Germany and France may trail countries including the US, UK, Australia, Ukraine, and Singapore, despite strong national policies. Factors include digital sovereignty concerns and the concentration of older manufacturing and operational systems. For leaders beginning this work, David recommends speaking with suppliers, establishing internal ownership, reviewing business continuity plans, and creating a cryptographic bill of materials covering certificates, algorithms, libraries, applications, and devices. I'd love to hear your thoughts, so does your organization know where its cryptography lives and who controls its post-quantum readiness?
Food as Medicine: Why Medical Nutrition Therapy and Medically Tailored Meals Belong in Modern Healthcare: Registered dietitian nutritionist Leyla Muedin argues that food should be treated with the same rigor as medication through medical nutrition therapy (MNT) and “diet prescriptions,” integrating nutrition into treatment plans rather than leaving it as optional advice. She cites evidence that medically tailored meals (MTMs) can improve outcomes and reduce costs, including a Health Affairs simulation estimating $23.7B in first-year net savings nationwide and a Nature Medicine analysis of a Massachusetts Medicaid demonstration (2020–2023) showing MTM recipients had 31% fewer hospitalizations, 20% fewer emergency visits, and $3,433 lower total healthcare costs, offsetting 98% of program costs. She discusses food insecurity, expanding Medicaid coverage via Section 1115 waivers, EHR integration, and how MTMs support adherence for conditions such as diabetes, cardiovascular disease, chronic kidney disease, depression, and IBS (including low FODMAP).
Fastly's revenue just re-accelerated into the mid-20% range — but our reverse DCF says the stock still needs 22%+ FCF growth for a decade to justify $26. Here's why that's a hard pass for now.Part 3 of our CDN series puts Fastly under the microscope after comparing it against Cloudflare and Akamai. We walk through our full investment thesis checklist — supply chain position, technology stickiness, revenue model, and capital structure — before running a reverse DCF on Fastly's free cash flow per share.Revenue growth has re-accelerated, and operating margins are improving, but GAAP profitability still lags Cloudflare, stock-based compensation remains elevated relative to revenue, and share dilution is running well above our target threshold. We also look at customer stickiness — including the loss of a major account to Cloudflare — as a proxy for platform depth and competitive moat.The result: Fastly lands on our watchlist rather than our buy list, with a price level flagged for renewed interest if shares pull back meaningfully. We close the series by connecting CDN infrastructure to the broader AI infrastructure buildout, and how a small CDN/cybersecurity basket — anchored by Cloudflare — fits inside a semiconductor and infrastructure-focused portfolio.Research-backed analysis, not a stock tip. Always do your own due diligence.—Members of Semiconductor Insider get our complete company-by-company research, valuation models, and portfolio allocation notes on Cloudflare, Akamai, and Fastly, plus weekly live Q&A and a growing set of tools to build your process: https://www.chipstockinvestor.comAll our socials: https://linktr.ee/chipstockinvestorIf you're getting value from the show, follow so you don't miss the next one.—Disclosure: Some links above are affiliate links. If you buy something through them, we might earn a little coffee money — thanks for helping us (Kasey) fuel our caffeine addiction.Content in this episode is for general information or entertainment only and is not specific or individual investment advice. Forecasts and information presented may not develop as predicted, and there is no guarantee any strategies presented will be successful. All investing involves risk, and you could lose some or all of your principal. CSI doesn't own shares of Fastly.
Supplements and Morning Coffee: Timing Iron, Zinc, Calcium, B Vitamins, and Vitamin D: Nutritionist Leyla Muedin explains that coffee (and tea) can interfere with nutrient absorption and digestion, so certain supplements shouldn't be taken with morning coffee. Coffee's tannins and polyphenols can significantly reduce non-heme iron absorption (decaf doesn't prevent this), and similar binding issues may affect zinc; she recommends taking iron with water at least 1–2 hours away from coffee and pairing it with vitamin C. Because caffeine may increase urination, B vitamins (especially thiamine) may be lost more readily, so she suggests taking them with food but not with coffee. Vitamin D is best taken with a fat-containing meal (not washed down with coffee), and calcium supplements should be separated from coffee since caffeine can slightly increase calcium loss. She also notes interactions such as green tea reducing folate absorption, spinach oxalates limiting mineral absorption, phytates in bran/legumes reducing iron and zinc absorption, and calcium (milk or supplements) cutting iron absorption, emphasizing timing rather than eliminating these foods.
Cloudflare is growing 30%+ a year — but our supply chain mapping shows a warning sign most investors are missing.In this deep dive, we map the entire CDN supply chain — from hyperscaler and neocloud infrastructure down to enterprise software and e-commerce end markets — using our new Custom Supply Chain research tool. We break down where Cloudflare, Akamai, and Fastly actually sit relative to vertically integrated competitors like AWS, Microsoft, and Google, all of whom now run in-house CDNs.We cover how neoclouds like CoreWeave and Nebius fit into the AI infrastructure picture, why DigitalOcean's CDN relationship with Cloudflare matters, and which enterprise software names (Salesforce, ServiceNow, SAP, Palo Alto Networks) rely on which providers. Then we use the mapping to evaluate competitive positioning, pricing power, and where profit is actually accruing in the data center and cloud infrastructure ecosystem.If you're researching Cloudflare, Akamai's turnaround potential, or Fastly's multi-CDN diversification thesis, this framework will change how you evaluate these names.Members of Semiconductor Insider get our complete company-by-company research, valuation models, and portfolio allocation notes on Cloudflare, Akamai, and Fastly, plus weekly live Q&A and a growing set of tools to build your process: https://www.chipstockinvestor.comAll our socials: https://linktr.ee/chipstockinvestorIf you're getting value from the show, follow so you don't miss the next one.—Disclosure: Some links above are affiliate links. If you buy something through them, we might earn a little coffee money — thanks for helping us (Kasey) fuel our caffeine addiction.Content in this episode is for general information or entertainment only and is not specific or individual investment advice. Forecasts and information presented may not develop as predicted, and there is no guarantee any strategies presented will be successful. All investing involves risk, and you could lose some or all of your principal. CSI owns shares of Cloudflare.
CDNs have quietly become one of the most important layers of internet and AI infrastructure, moving everything from website traffic to large-scale AI data transfer. In this episode we compare the three public leaders — Cloudflare (NET), Akamai (AKAM), and Fastly (FSLY) — on revenue growth, gross margin, operating margin, free cash flow margin, and balance sheet strength.We also give you a first look at the new Chip Stock Investor research dashboard, launching in September at chipstockinvestor.com. The CDN comparison is the demo: everything you hear us pull up, you'll be able to run yourself.A few things that stood out:Cloudflare, another 30%+ quarter (33.5% growth) with net cash, but trading near 40x sales at a $110B+ market cap. Akamai is larger by revenue, but carrying $4.2B in net debt after an acquisition-led push into cloud infrastructure.Fastly, growth re-accelerated past 20%, putting the smallest of the three back in the value conversation.Full company-by-company research, valuation models, and portfolio allocation notes go live for Semiconductor Insider members in September: https://www.chipstockinvestor.comAll our socials: https://linktr.ee/chipstockinvestorChapters:(0:00) Why the CDN market matters for AI infrastructure(1:00) What a CDN actually does(3:00) How each company differentiates: security, compute, observability(3:45) Live dashboard: market cap and revenue(4:00) Revenue growth: Cloudflare's 33.5% vs. Akamai's slowdown(5:00) Margins that matter: gross, operating, free cash flow(6:00) Balance sheet: net cash vs. Akamai's $4.2B net debt(6:30) Long-term revenue trajectory(7:00) Cloudflare valuation: is 40x sales too rich?(8:00) Portfolio moves: trimming Cloudflare, Akamai's turnaround, Fastly's upsideCSI owns shares of Cloudflare. Content is for general information or entertainment only and is not individual investment advice. All investing involves risk, and you could lose some or all of your principal.
Managing High Homocysteine with MTHFR Variants and the Role of Vitamin C in Brain Aging: Registered dietitian nutritionist Leyla Muedin discusses MTHFR genetic variants (C677T and A1298C), their links to impaired methylation, homocysteine, SAMe, mood issues, migraines, vitamin deficiencies, and pregnancy complications, noting many people are asymptomatic and some feel worse on methylated B vitamins and do better on standard formulations. Responding to a listener with C677T, high homocysteine, and borderline methylmalonic acid, she reviews optimal homocysteine targets and outlines other causes of elevated homocysteine such as hypothyroidism/subclinical hypothyroidism, kidney failure, obesity, hypertension, diabetes, smoking, inactivity, and medications (atorvastatin, methotrexate, fenofibrate). She suggests checking these factors, considering absorption issues (intrinsic factor) for B12, and trialing SAMe and more trimethylglycine, with possible pharmacologic folate if needed. She then summarizes an observational Japanese study (n=2,044 adults >64) linking lower plasma vitamin C to reduced gray matter and weaker default mode network connectivity, and notes diet and blood sugar can affect vitamin C status.
What are your thoughts on Cleveland Clinic's assessment of fish oil supplements?If I want to go on your sleep protocol, should I order all of the supplements or choose one?Do you still recommend individual assessments to determine natural treatments for anxiety and depression?Is taking Bergamot for cholesterol really effective?
The new vaccine schedule recommendationsMy urologist is giving me grief that my vitamin D level is too highWhich nattokinase do you recommend to treat long covid?Is the vitamin K in your bone protocol different from the heart protocol?What about methylated B vitamins for brain vs. heart health?
Lowering A1C in Prediabetes and Using Less Insulin on a Low-Carb Diet: Leyla Muedin, a registered dietitian nutritionist, answers listener questions about blood sugar and insulin. Responding to Rita, whose hemoglobin A1C rose from 5.6 to 5.8, Layla says “glucose hacks” to blunt carb absorption aren't appropriate at that level and recommends a strict very low-carb/keto approach (under 25 grams of total carbs per day), avoiding sugar, starchy vegetables, fruit (except avocado), sweetened beverages, and even alternative sweeteners and low-carb processed products; she suggests retesting A1C after three months and avoiding testing during illness or inflammation. She also addresses Joy, a type 1 diabetic, affirming low-carb eating to reduce insulin needs and weight gain, criticizing an insurance pricing structure that charges more when insulin is used more slowly, and expressing concern about doctors prescribing insulin too quickly for type 2 diabetes instead of dietary intervention.
My HgbA1c is steady at 5.5. Could I reduce my metformin dose against the advice of my endocrinologist who states it's good for longevity?I have a large gallstone and am wondering what the pros and cons of having my gallbladder removed are.I take a lot of vitamins and am wondering if there's any easier way to ingest them?
Could you please comment on the new study that finds protein restriction could slow aging?Considerations for protein intake across the lifespanMy bone mineral density has improved with strontium. Should I stop taking it? What about vitamin K2?
PHP Alive and Kicking – August 4, 2026 Hosts: Chris Miller (standing in solo while Mike is on holiday) Mike escaped to a beach so Chris hosts alone with special guest Derick Rethans. Expect date-time philosophy, PHP 8.6 goodies, Xdebug secrets, deprecation drama, and a heated debate about how to queue at a pub. From University Websites to Committing to PHP Derick traces his PHP origins back to his university days, building websites that needed database connectivity. ASP.NET was an option, but nobody wanted to pay for it — Linux was cool, and PHP was easy to start using. That combination hooked him early. His very first accepted contribution came from a practical need: everyone wanted centered Shockwave Flash films on their pages, back before CSS even existed. Centering meant knowing the width of a file, and while getimagesize() already existed (and still works today), it didn’t understand Flash. Derick added that support. From there he fell into bug triage, spending several years working through the issue tracker alongside Jani Taskinen (whose “Sniper” name still shows up in commit logs). For a long time it was just the two of them reproducing and fixing bugs — an important task that gets neglected easily, which is exactly how backlogs of a thousand issues and pull requests build up. The Eternal Problem of Date and Time Chris and Derick dig into why date-time bugs are so hard to triage: date algorithms are genuinely complicated, and it takes real time to figure out whether a report is a user’s mistake or an actual PHP bug. Crashes are easy to reproduce; subtle date arithmetic is not. The core philosophical question is “what does adding a month even mean?” If it’s January 31st and you add a month, PHP historically just bumps the month number, producing February 31st, which overflows to March 2nd or 3rd. But most people who add a month really just want the next month and don’t care about day counts — so “next month” is conceptually distinct from “add a month.” Derick has been brainstorming better interfaces so people can’t make these mistakes, though it’s a lot of work. They touch on Carbon as a unified interface people understand, but agree that making Carbon the language standard isn’t the right move. At the language level you need something that works for everybody and ideally doesn’t break existing code. What’s Coming in PHP 8.6 The first new time class is landing: a Duration object representing seconds and nanoseconds within a specific range, living in the Time namespace. It’s a trial run for new APIs and immediately useful — for example, passing a duration to sleep or to timeouts in the new polling API, rather than juggling raw integers. Another highlight is partial function application. With the pipe operator from 8.5, piping into anything that takes more than one argument meant wrapping it in a closure (and extra parentheses because of how the parser works). Partials let you pre-fill some arguments so the resulting callable accepts just one — perfect for pipelines. There’s also TLS session resumption support for streams, which lets OpenSSL shortcut the expensive session setup on repeated TLS connections. Bigger stream-layer work by Jakub Zelenka of the PHP Foundation is underway too, but that’s a huge job on old code and won’t make 8.6 — Chris and Derick both note the pain of keeping a year-and-a-half-long project in sync with the master branch. Xdebug in 8.6 and the Xdebug Cloud Xdebug’s recent headline feature (shipped with 8.5) is native path mapping, which lets you configure remote-to-local path mappings inside Xdebug itself instead of your IDE — handy when your code runs in Docker or on a dev machine. Feedback since release is driving quality-of-life improvements. For 8.6, relatively little is broken, though a change to how PHP reports line numbers needs untangling so debugging stops on the correct lines. Derick also has a new code-coverage implementation that gives better, more correct results at roughly a 10% speed cost. He’d rather ship correct output than fast output — and points out that PHPCov may be quicker but skips path and branch coverage entirely. The pair discuss how branch coverage doubles your test count at every branching point, and how Xdebug has a hard limit (around 64K) to avoid running out of memory on pathological code. Finally, Chris asks about Xdebug Cloud — a paid service that enables debugging where networking otherwise wouldn’t, such as remote teams sharing a single development machine (an SSH tunnel only lets one person listen on the debug port). It’s £15/month or £150/year for an individual, priced similarly to Packagist’s private packages, and helps fund Derick’s ongoing Xdebug work. He plans to do more marketing about it this year. Deprecations, Consensus, and Two-Thirds Votes Every year PHP collects a big list of deprecations — around 20 to 25 this cycle — voted on separately. Derick is more reluctant than most to approve them, arguing many offer no clear user benefit. His examples: deprecating metaphone() (whose suggested Composer replacement ironically relies on the internal function) and the dechunk filter (which can’t really be removed because HTTP streams use it internally). The list() deprecation is another sore point — Chris uses it, and the vote is tied 21–21 with one abstention, so it won’t pass under the two-thirds rule. Derick reminds everyone that “yes” needs to be twice “no.” Returning from a finally block is another candidate that makes little sense to use but hurts nothing to keep. Chris and Derick reflect on how voting was originally meant to confirm consensus reached on the mailing list, not to be the decision itself. A 50%+1 result isn’t consensus; two-thirds is the compromise, even if true 75–80% agreement would be ideal. Joe notes many deprecations are groundwork to reserve keywords for future RFCs — which raises the perennial question of how you measure real-world usage across Composer’s dependency chains. Infrastructure, the Website, and the Next Generation The PHP infrastructure has been converted to an Ansible-based repository over the last year and a half (largely by Derick, with help from Joe), replacing a wild mix of individually maintained servers — one was still running FreeBSD 4.3. They’ve also migrated to a new CDN, which brought surprises: a default one-month cache, ignoring the query string in cache keys, and even dark/light mode being an organization-wide setting rather than per-user. On the website side, everything currently lives in a single root directory of 1999-vintage code, and there’s a long-pending patch to restructure it. The PHP Foundation’s ambassadors program — with speaking, marketing, and research streams — aims to make the very techy php.net homepage speak to CTOs and newcomers about who uses PHP and why it’s a thriving project (only 31-ish years old, versus C’s 60). The conversation closes on caretakers and the next generation of contributors. Triage, they stress, doesn’t require deep internals knowledge — just reading reports to see if they still make sense is hugely valuable. Security and infrastructure access necessarily stay gatekept for trust reasons, and both agree a bus factor of one (or even two) isn’t good enough. Chris admits he’s struggling to name people who are both nice and know infra. Links from the show: Join us live in Discord — discord.phparch.com Watch live on YouTube — youtube.com/phparch PHP Tek Conference 2027 — Call for Papers now open PHP Arch Swag Store — store.phparch.com Xdebug — and Xdebug Cloud for shared debugging Magazine discount code ALIVE3 — three free months on an annual digital subscription Host: Chris Miller X: @ccmiller2018 Mastodon: @miller@phpc.social Bluesky: @ccmiller2018.bsky.social PHPArch.me: @miller Mike Page Mastodon: @MikePageDev@phpc.social PHPArch.me: @mikepagedev Streams: Youtube Channel Twitch Connect & Hire PHP Architect Website Twitter/X Mastodon Hire PHP Developers Looking to hire PHP developers? Email support@phparch.com – the team is available for consulting, infrastructure work, Ansible playbooks, and code review. Partner This podcast is made a little better thanks to our partners Displace Infrastructure Management, Simplified Automate Kubernetes deployments across any cloud provider or bare metal with a single command. Deploy, manage, and scale your infrastructure with ease. https://displace.tech/ OurCVEs Your security posture, on autopilot with OurCVEs CodeRabbit Cut code review time & bugs in half instantly with CodeRabbit. PHP Architect Consulting Your PHP codebase deserves a partner, not a contractor PHP Architect provides long-term technical partnerships for organizations that need senior-level PHP expertise that you can depend on. https://www.phparch.com/consulting/ Music Provided by Epidemic Sound https://www.epidemicsound.com/ Join Us Live Next Week Youtube Channel Got feedback? Join us on Discord at discord.phparch.com The post PHP Alive and Kicking 2026.08.04 appeared first on PHP Architect.
Leyla Muedin, a registered dietitian nutritionist in New York City, discusses the growing shift from symptom-only “sick care” to a clinically grounded holistic approach to health and recovery. She argues that self-guided wellness routines can leave gaps when underlying medical issues, mental health conditions, substance use disorders, or trauma remain unaddressed, and emphasizes integrating evidence-based clinical evaluation (including labs and deficiency testing) with lifestyle practices. She explains how treating symptoms in isolation misses connections (e.g., stress, sleep, grief) and defines true holistic care as addressing physical, mental, emotional, relational, environmental, and purpose-related factors without rejecting medical treatment. Key components include consistent movement, individualized nutrition built on basics, nervous system regulation (sleep, nature, breathing, meditation/prayer), meaningful social connection, and a sense of purpose as clinically relevant to resilience.
My 25-year-old son has bipolar disorder and can't tolerate his medications. Any natural recommendations?Is chondroitin effective? It's in my collagen capsules, which I take to hopefully reduce wrinklesI believe I am still suffering from the negative effects of COVID. What would you suggest I take?
Is there evidence for statins in the treatment of aortic valve stenosis?How the bacteria behind gum disease can affect heart healthWouldn't it be better to resume taking probiotics after finishing a round of antibiotics?Would it be safe to take olive leaf extract with amoxicillin?I'm considering surgery for varicose veins. Is this just a temporary fix? Can they return?
Benedicte shares her takeaways from the plumbing course. Benedikt goes on a few AWS adventures.Benedicte had so much fun and learned a lot from her plumbing course, even sharing a mindblowing tip of using a balloon to help clear out water from the tap mechanisms during winter. On the work front, their system at Whee! is now live syncing prospects and customers to their email list. Benedicte's also figuring out how to fix the data inconsistency between the bike availability on their website versus the actual availability of bikes at the workshop.The Userlist team reworked their entire data model for themes to support the new stuff. Benedikt also set up a proper CDN for user uploaded assets so there's client side caching. He also took some time to set up Userlist on AWS but is quite unsure if they should move over for good because of the complexity and the unknowns.
What Triggers Age-Related Belly Fat? New Stem Cell Findings and a Nutrition Perspective: Nutritionist Leyla Muedin discusses research from City of Hope (published in Science) on why belly fat increases with age even without major weight gain, emphasizing the health risks of visceral fat as an endocrine organ linked to inflammation, diabetes, heart disease, and accelerated aging. The study suggests aging activates adipocyte progenitor cells (APCs) and produces an age-specific stem cell population called committed preadipocytes (CP-As) that generate new fat cells, with experiments showing older APCs create more fat cells even when transplanted into young mice. Single-cell RNA sequencing identified greater CP-A activity in middle-aged mice and similar cells in higher numbers in middle-aged human tissue. Researchers implicate the LIFR signaling pathway and propose future therapies to block these cells, while Leyla questions root causes and argues metabolic dysfunction—insulin resistance, hyperinsulinemia, high carbohydrate intake, and sedentary behavior—should be addressed nutritionally rather than via a pill.
Nature or nurture—which is more important when it comes to health conditions?Would I benefit from taking nattokinase along with my statin?Mechanism of action of nattokinase vs. statin medications on coronary artery health
My LDL is 421, and I have mild to moderate aortic stenosis. Must I take a statin?Lean Mass Hyper-responders on low carb diets explainedWould you consider writing a book about health in advancing age?A revisit of Dr. Hoffman's published booksWhat is the best dose of lithium orotate for therapeutic benefit?Must I exercise fasted? Why?
Vitamin B12 Deficiency--The “Aging” Symptoms You Shouldn't Ignore: Leyla Muedin, a registered dietitian nutritionist in New York City, discusses vitamin B12 deficiency as a common problem that can mimic normal aging, noting adults need only about two micrograms daily to support red blood cells, nerves, and DNA. She reviews the history of liver treatment for pernicious anemia and explains that deficiency remains common in older adults, vegans/vegetarians, and people with impaired absorption due to low stomach acid, autoimmune gastritis, weight loss surgery, or medications such as metformin and proton pump inhibitors. Symptoms can develop slowly and include fatigue, weakness, shortness of breath, numbness/tingling, poor balance, memory issues, and brain fog; she advises medical evaluation and B12 testing rather than assuming aging or relying on wellness-clinic injections when levels are normal. She emphasizes B12 is primarily in animal foods, so vegans need supplements, and notes broader nutrient shortfalls she sees in vegan clients.
How do I find a preventive cardiologist in northern New Jersey?What is the best supplement for dissolving bone spurs?What is the half-life of vitamin D, either by supplement or sun exposure?What do you think about mushroom coffee? Does it have any health benefits?Please discuss how strontium affects DEXA scan results
Does coffee really dehydrate you? A deeper dive on this important topicHelp for nighttime urinationPlease discuss aortic dissection
Registered dietitian Leyla Muedin discusses a Frontiers in Microbiology paper suggesting certain probiotics may help sequester heavy metals. The study, sponsored by the Italian company Probiotical and conducted with University of Ghent and University of Piedmont Orientale, researchers used in vitro testing and the SHIME gut simulator to assess Lactiplantibacillus plantarum, Lactobacillus crispatus, and Lactobacillus acidophilus against cadmium, lead, chromium, and mercury. L. plantarum and L. crispatus reduced metal bioavailability primarily in the simulated colonic phase, while L. acidophilus showed minimal detoxification; mercury was least reduced (~10%). An ex vivo mouse-intestine system found probiotic pre-incubation of metals preserved epithelial integrity and reduced inflammatory responses. Leyla notes limitations: corporate funding, only three strains tested, and no in vivo or human trials, though the findings support further animal and clinical research.
You learn at least five new things every episode, and this one stacks them fast. Roll your Apple Watch crown instead of tapping it to keep Sleep mode from searing your eyes, then hit Command-Shift-F in the Finder to jump straight to Recents when a saved file vanishes into the void. When a listener asks how to archive iMessages, you’ll meet iMazing, Shottr’s scrolling screenshots, privacy.apple.com, and a public-key-encryption rabbit hole that explains why even Apple can’t hand your texts back. You’ll also learn to Control-click the Printers list to reset the entire CUPS printing system, and to check every app’s Rosetta versus Apple Silicon status before sluggish performance quietly fools you, because Rosetta survives macOS 27 but finally bows out in fall 2027, so audit those Intel holdouts now. Then the questions roll in. You’ll troubleshoot a PDF that downloads on one Mac but stalls on another (think DNS blocks, CDN handoffs, stale session cookies, and a fast browser swap), wrestle Apple TV lip-sync into line by killing soundbar processing and matching frame rates, and chase a self-dimming iPad back to its ambient-light sensor and screen protector. Cool Stuff Found delivers a Beelink dock that sidesteps Apple’s storage surcharges and Pixette for reviving an ancient iPad as a photo frame. And when refurb Mac minis sell out in two hours and Apple nudges prices up overnight? Don’t Get Caught letting hope prevail like Dave did, grab it the moment you see it, because that cart won’t hold it for you. 00:00:00 Mac Geek Gab 1149 for Monday, July 6th, 2026 July 6th: National Air Traffic Control Day 00:02:47 A quick video from Dave's daughter's wedding MGG Monthly Giveaway – Win a license to Mole Quick Tips 00:00:01 Jan Landy-QT-Roll Your Apple Watch crown in Sleep Mode to go easy on your eyes 00:06:36 Claire-QT-To Find something you just added, Command-Shift-F in Finder for your Recents list 00:11:02 GW-I wish Apple had a way to archive Messages iMazing (and formerly PhoneView) Remember privacy.apple.com 00:19:09 Message in iCloud and Public Key Encryption Shottr's scrolling screenshots 00:23:33 WillRun4Fun-QT-Control-click in Printers list to Reset Printing System Enable CUPS web page on your Mac Visit https://localhost:631/printers/ If that fails, open Terminal and run “cupsctl WebInterface=yes” to enable it 00:26:14 TheDaveAbides-QT-Check your apps’ Rosetta/Apple Silicon status 00:35:28 Andrew-QT-Buy your refurbs immediately…don’t just leave in your cart Refurb Tracker RefurbMe AppTamer Sponsors 00:40:49 SPONSOR: Keeper. Right now, Keeper is offering our listeners 60% off personal and family plans at https://Keepersecurity.com/MGG. This offer is only for podcast listeners! 00:42:10 SPONSOR: Even Realities G2. Use promo code MGG at evenrealities.com to get 10% off Even Ring 1 and/or Even Clip when you add them to your Even G2 order. 00:43:48 SPONSOR: Decagon. Ready to transform your customer support? Decagon helps companies create personalized, concierge-style customer experiences with AI agents across chat, email, voice, and SMS. Go to https://decagon.ai/MGG to get a personalized demo and see what Decagon can do for your team. Your Questions Answered and Tips Shared! 00:45:16 Mike-Why can I download a pdf on ONE computer, but not another? 00:53:01 David-How do I resolve Apple TV lip sync issues? YouTube A/V sync videos AWOL 2500 Projector Sonos Soundbars 01:04:52 Larry-iPad Dims When I don't want it to Cool Stuff Found 01:12:44 Mike-CSF-Belkin Beelink Mac mini storage dock (and others like it) 01:14:24 Greg-CSF-1147-Pixette for displaying photos on an old iPad 01:16:55 MGG 1149 Outtro MGG Monthly Giveaway Bandwidth Provided by CacheFly Pilot Pete's Aviation Podcast: So There I Was (for Aviation Enthusiasts) The Debut Film Podcast – Adam's new podcast! Dave's Business Brain (for Entrepreneurs) and Gig Gab (for Working Musicians) Podcasts MGG Merch is Available! Mac Geek Gab iOS app Mac Geek Gab YouTube Page Mac Geek Gab Live Calendar This Week's MGG Premium Contributors MGG Apple Podcasts Reviews feedback@macgeekgab.com 224-888-GEEK Active MGG Sponsors and Coupon Codes List BackBeat Media Podcast Network
Bone Health Beyond Calcium: Vitamin D, K, Protein, Medications, and Metabolic Risks: Registered dietitian nutritionist Leyla Muedin discusses factors affecting bone health, osteopenia/osteoporosis, and limitations of bone mineral density as a measure of bone strength. She emphasizes optimizing vitamin D via 25-hydroxy D testing (aiming roughly 55–85 and avoiding over 100), ensuring vitamin K for proper calcium placement, and addressing malabsorption from GI conditions, food intolerances, or inflammation. She notes long-term proton pump inhibitor use can impair calcium and magnesium absorption and increase osteoporosis risk. Diet considerations include avoiding overly grain-heavy, acid-forming patterns and ensuring high biological value protein; she also mentions heavy metals affecting bones. Additional assessment includes magnesium and DHEA sulfate, plus resistance and balance training (ideally three times weekly). She highlights research linking hyperinsulinemia/type 2 diabetes/cardiovascular disease to fragility fractures despite normal or higher bone density, proposing carbohydrate restriction, fasting, and ketosis to improve bone remodeling via osteocalcin and mitochondrial function.
I've worked for many years on my feet and had surgery on both knees. How much glucosamine should I take?Can you discuss oral vs. IV chelation? How do you determine which is appropriate?How important is nitric oxide, and how can I increase mine?Are there any supplements I should stop taking before getting blood tests?
Carnivore diet controversiesWhat is a normal oxygen saturation? Mine has been 92-93 lately? Is that okay?
Topics covered in this episode: Free-threaded Python: past, present, and future django-admin-site-search Qwen 3.6 27B is the sweet spot for local development A large batch of PEPs are finalized Extras Joke Watch on YouTube Show Intro Sponsored by us! Support our work through: Our courses at Talk Python Consulting from Six Feet Up Connect with the hosts Michael: Mastodon / BlueSky / X / LinkedIn Calvin: Mastodon / BlueSky / X / LinkedIn Show: Mastodon / BlueSky / X Join us on YouTube at pythonbytes.fm/live to be part of the audience. Usually Tuesday at 7am PT. Older video versions available there too. Finally, if you want an artisanal, hand-crafted digest of every week of the show notes in email form? Add your name and email to our friends of the show list, we'll never share it. Calvin #1: Free-threaded Python: past, present, and future The GIL has prevented true multi-threaded parallelism in CPython since the beginning — multiple past attempts to remove it failed on performance grounds Sam Gross at Meta finally solved it; his work became PEP 703 and ships as free-threaded CPython today Python 3.13 was experimental with 20–40% single-threaded slowdown; 3.14 brought that to 0–10% Python 3.15 (October 2026) delivers a unified ABI — one extension binary works on both GIL and free-threaded builds Already >50% of the top PyPI binary wheels support free threading Wouters predicts free-threaded becomes the default between 3.16–3.20 (2027–2031), with the GIL eventually disappearing next decade Michael #2: django-admin-site-search via Adam Parkin A global/site search modal for the Django admin, by Ahmed Aljawahiry. Hit cmd+k anywhere in the admin and you get a command-palette-style search window, kind of like the one in VS Code. It doesn't just search one model's list page. It searches your entire site in one box: App labels Model labels and field attributes Actual model instances (your data) Two ways to search the instances: model_char_fields (the default): runs an __icontains across every CharField (and subclasses) on the model. Zero config, works out of the box. admin_search_fields: defers to each ModelAdmin's existing get_search_results(), so it respects the search_fields you've already set up. The part I like: it's permission-aware out of the box. Users only see results for the apps and models they actually have view permission on, so you're not leaking anything through search. Results appear as you type, with throttling/debouncing so you're not hammering the server on every keystroke, and it's full keyboard nav: cmd+k to open, up/down to move, enter to go. It's responsive, does dark and light mode, and it pulls Django's built-in admin CSS variables so it just matches whatever admin theme you're running. Under the hood it's Alpine.js, but bundled into static so there's no external CDN dependency. Setup is about what you'd expect: pip install django-admin-site-search, add it to INSTALLED_APPS, mix the AdminSiteSearchView into your AdminSite, and drop a few template includes into base_site.html. Supports Python 3.8 through 3.14 and Django 3.2 through 6.0, MIT licensed, and everything is overridable if you want to skip certain models, add TextField matching, etc. Calvin #3: Qwen 3.6 27B is the sweet spot for local development Qwen 3.6 27B is being called the first local model that genuinely competes as a general-purpose intelligence — benchmarks put it at roughly mid-2025 frontier level (comparable to GPT-5 / Claude Sonnet 4.5) Runs locally via llama.cpp; on an M5 MacBook Max with 8-bit quantization + multi-token prediction, it hits ~32 tokens/sec using ~42GB RAM 4-bit quantization gets it under 18GB, runnable on 32GB devices; Nvidia RTX cards run it even faster The dense 27B is recommended over the faster MoE 35B A3B — author prefers higher quality output over raw speed Privacy and reliability are the pitch: fine-tunable, can't be taken down, suitable for sensitive/proprietary data Author sees this as a stepping stone — frontier open-weight models like GLM 5.2 are now locally runnable with company-grade hardware, and smarter-still local models are coming Michael #4: A large batch of PEPs are finalized A bunch of PEPs went from accepted to final. 668, 687, 691, 699, 701, 703, 728, 770, 773, 829 But this wasn't them making their way into CPython. It's an admin sorta thing. (Thanks PyCoders) See the commit. Extras Calvin: More fun bling for your terminal this time - https://charm.land/ Michael: Follow up from pls, What the pls? Thanks Pito. Joke: BEMoji A production-grade utility and component framework built entirely on emoji class names via Jeff Triplett
Eat Strong, Move Smart: Stefani Sassos on Food, Fitness & Health Claims That Matter After 50 The Not Old Better Show, Good Housekeeping, Good Better Best Interview Series