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Food as Medicine: Why Medical Nutrition Therapy and Medically Tailored Meals Belong in Modern Healthcare: Registered dietitian nutritionist Leyla Muedin argues that food should be treated with the same rigor as medication through medical nutrition therapy (MNT) and “diet prescriptions,” integrating nutrition into treatment plans rather than leaving it as optional advice. She cites evidence that medically tailored meals (MTMs) can improve outcomes and reduce costs, including a Health Affairs simulation estimating $23.7B in first-year net savings nationwide and a Nature Medicine analysis of a Massachusetts Medicaid demonstration (2020–2023) showing MTM recipients had 31% fewer hospitalizations, 20% fewer emergency visits, and $3,433 lower total healthcare costs, offsetting 98% of program costs. She discusses food insecurity, expanding Medicaid coverage via Section 1115 waivers, EHR integration, and how MTMs support adherence for conditions such as diabetes, cardiovascular disease, chronic kidney disease, depression, and IBS (including low FODMAP).
Supplements and Morning Coffee: Timing Iron, Zinc, Calcium, B Vitamins, and Vitamin D: Nutritionist Leyla Muedin explains that coffee (and tea) can interfere with nutrient absorption and digestion, so certain supplements shouldn't be taken with morning coffee. Coffee's tannins and polyphenols can significantly reduce non-heme iron absorption (decaf doesn't prevent this), and similar binding issues may affect zinc; she recommends taking iron with water at least 1–2 hours away from coffee and pairing it with vitamin C. Because caffeine may increase urination, B vitamins (especially thiamine) may be lost more readily, so she suggests taking them with food but not with coffee. Vitamin D is best taken with a fat-containing meal (not washed down with coffee), and calcium supplements should be separated from coffee since caffeine can slightly increase calcium loss. She also notes interactions such as green tea reducing folate absorption, spinach oxalates limiting mineral absorption, phytates in bran/legumes reducing iron and zinc absorption, and calcium (milk or supplements) cutting iron absorption, emphasizing timing rather than eliminating these foods.
Managing High Homocysteine with MTHFR Variants and the Role of Vitamin C in Brain Aging: Registered dietitian nutritionist Leyla Muedin discusses MTHFR genetic variants (C677T and A1298C), their links to impaired methylation, homocysteine, SAMe, mood issues, migraines, vitamin deficiencies, and pregnancy complications, noting many people are asymptomatic and some feel worse on methylated B vitamins and do better on standard formulations. Responding to a listener with C677T, high homocysteine, and borderline methylmalonic acid, she reviews optimal homocysteine targets and outlines other causes of elevated homocysteine such as hypothyroidism/subclinical hypothyroidism, kidney failure, obesity, hypertension, diabetes, smoking, inactivity, and medications (atorvastatin, methotrexate, fenofibrate). She suggests checking these factors, considering absorption issues (intrinsic factor) for B12, and trialing SAMe and more trimethylglycine, with possible pharmacologic folate if needed. She then summarizes an observational Japanese study (n=2,044 adults >64) linking lower plasma vitamin C to reduced gray matter and weaker default mode network connectivity, and notes diet and blood sugar can affect vitamin C status.
What are your thoughts on Cleveland Clinic's assessment of fish oil supplements?If I want to go on your sleep protocol, should I order all of the supplements or choose one?Do you still recommend individual assessments to determine natural treatments for anxiety and depression?Is taking Bergamot for cholesterol really effective?
The new vaccine schedule recommendationsMy urologist is giving me grief that my vitamin D level is too highWhich nattokinase do you recommend to treat long covid?Is the vitamin K in your bone protocol different from the heart protocol?What about methylated B vitamins for brain vs. heart health?
Anamika Gadia, National Leader of Industrial Markets at KMPG Canada, joins the podcast to discuss the organization's recent survey, polling Cdn. manufacturers and finding that four in ten are eyeing a U.S. production move. We take a deep dive into the survey, and what it means for businesses looking at their next move in a tight, tariff-affected economy.
Lowering A1C in Prediabetes and Using Less Insulin on a Low-Carb Diet: Leyla Muedin, a registered dietitian nutritionist, answers listener questions about blood sugar and insulin. Responding to Rita, whose hemoglobin A1C rose from 5.6 to 5.8, Layla says “glucose hacks” to blunt carb absorption aren't appropriate at that level and recommends a strict very low-carb/keto approach (under 25 grams of total carbs per day), avoiding sugar, starchy vegetables, fruit (except avocado), sweetened beverages, and even alternative sweeteners and low-carb processed products; she suggests retesting A1C after three months and avoiding testing during illness or inflammation. She also addresses Joy, a type 1 diabetic, affirming low-carb eating to reduce insulin needs and weight gain, criticizing an insurance pricing structure that charges more when insulin is used more slowly, and expressing concern about doctors prescribing insulin too quickly for type 2 diabetes instead of dietary intervention.
My HgbA1c is steady at 5.5. Could I reduce my metformin dose against the advice of my endocrinologist who states it's good for longevity?I have a large gallstone and am wondering what the pros and cons of having my gallbladder removed are.I take a lot of vitamins and am wondering if there's any easier way to ingest them?
Could you please comment on the new study that finds protein restriction could slow aging?Considerations for protein intake across the lifespanMy bone mineral density has improved with strontium. Should I stop taking it? What about vitamin K2?
PHP Alive and Kicking – August 4, 2026 Hosts: Chris Miller (standing in solo while Mike is on holiday) Mike escaped to a beach so Chris hosts alone with special guest Derick Rethans. Expect date-time philosophy, PHP 8.6 goodies, Xdebug secrets, deprecation drama, and a heated debate about how to queue at a pub. From University Websites to Committing to PHP Derick traces his PHP origins back to his university days, building websites that needed database connectivity. ASP.NET was an option, but nobody wanted to pay for it — Linux was cool, and PHP was easy to start using. That combination hooked him early. His very first accepted contribution came from a practical need: everyone wanted centered Shockwave Flash films on their pages, back before CSS even existed. Centering meant knowing the width of a file, and while getimagesize() already existed (and still works today), it didn’t understand Flash. Derick added that support. From there he fell into bug triage, spending several years working through the issue tracker alongside Jani Taskinen (whose “Sniper” name still shows up in commit logs). For a long time it was just the two of them reproducing and fixing bugs — an important task that gets neglected easily, which is exactly how backlogs of a thousand issues and pull requests build up. The Eternal Problem of Date and Time Chris and Derick dig into why date-time bugs are so hard to triage: date algorithms are genuinely complicated, and it takes real time to figure out whether a report is a user’s mistake or an actual PHP bug. Crashes are easy to reproduce; subtle date arithmetic is not. The core philosophical question is “what does adding a month even mean?” If it’s January 31st and you add a month, PHP historically just bumps the month number, producing February 31st, which overflows to March 2nd or 3rd. But most people who add a month really just want the next month and don’t care about day counts — so “next month” is conceptually distinct from “add a month.” Derick has been brainstorming better interfaces so people can’t make these mistakes, though it’s a lot of work. They touch on Carbon as a unified interface people understand, but agree that making Carbon the language standard isn’t the right move. At the language level you need something that works for everybody and ideally doesn’t break existing code. What’s Coming in PHP 8.6 The first new time class is landing: a Duration object representing seconds and nanoseconds within a specific range, living in the Time namespace. It’s a trial run for new APIs and immediately useful — for example, passing a duration to sleep or to timeouts in the new polling API, rather than juggling raw integers. Another highlight is partial function application. With the pipe operator from 8.5, piping into anything that takes more than one argument meant wrapping it in a closure (and extra parentheses because of how the parser works). Partials let you pre-fill some arguments so the resulting callable accepts just one — perfect for pipelines. There’s also TLS session resumption support for streams, which lets OpenSSL shortcut the expensive session setup on repeated TLS connections. Bigger stream-layer work by Jakub Zelenka of the PHP Foundation is underway too, but that’s a huge job on old code and won’t make 8.6 — Chris and Derick both note the pain of keeping a year-and-a-half-long project in sync with the master branch. Xdebug in 8.6 and the Xdebug Cloud Xdebug’s recent headline feature (shipped with 8.5) is native path mapping, which lets you configure remote-to-local path mappings inside Xdebug itself instead of your IDE — handy when your code runs in Docker or on a dev machine. Feedback since release is driving quality-of-life improvements. For 8.6, relatively little is broken, though a change to how PHP reports line numbers needs untangling so debugging stops on the correct lines. Derick also has a new code-coverage implementation that gives better, more correct results at roughly a 10% speed cost. He’d rather ship correct output than fast output — and points out that PHPCov may be quicker but skips path and branch coverage entirely. The pair discuss how branch coverage doubles your test count at every branching point, and how Xdebug has a hard limit (around 64K) to avoid running out of memory on pathological code. Finally, Chris asks about Xdebug Cloud — a paid service that enables debugging where networking otherwise wouldn’t, such as remote teams sharing a single development machine (an SSH tunnel only lets one person listen on the debug port). It’s £15/month or £150/year for an individual, priced similarly to Packagist’s private packages, and helps fund Derick’s ongoing Xdebug work. He plans to do more marketing about it this year. Deprecations, Consensus, and Two-Thirds Votes Every year PHP collects a big list of deprecations — around 20 to 25 this cycle — voted on separately. Derick is more reluctant than most to approve them, arguing many offer no clear user benefit. His examples: deprecating metaphone() (whose suggested Composer replacement ironically relies on the internal function) and the dechunk filter (which can’t really be removed because HTTP streams use it internally). The list() deprecation is another sore point — Chris uses it, and the vote is tied 21–21 with one abstention, so it won’t pass under the two-thirds rule. Derick reminds everyone that “yes” needs to be twice “no.” Returning from a finally block is another candidate that makes little sense to use but hurts nothing to keep. Chris and Derick reflect on how voting was originally meant to confirm consensus reached on the mailing list, not to be the decision itself. A 50%+1 result isn’t consensus; two-thirds is the compromise, even if true 75–80% agreement would be ideal. Joe notes many deprecations are groundwork to reserve keywords for future RFCs — which raises the perennial question of how you measure real-world usage across Composer’s dependency chains. Infrastructure, the Website, and the Next Generation The PHP infrastructure has been converted to an Ansible-based repository over the last year and a half (largely by Derick, with help from Joe), replacing a wild mix of individually maintained servers — one was still running FreeBSD 4.3. They’ve also migrated to a new CDN, which brought surprises: a default one-month cache, ignoring the query string in cache keys, and even dark/light mode being an organization-wide setting rather than per-user. On the website side, everything currently lives in a single root directory of 1999-vintage code, and there’s a long-pending patch to restructure it. The PHP Foundation’s ambassadors program — with speaking, marketing, and research streams — aims to make the very techy php.net homepage speak to CTOs and newcomers about who uses PHP and why it’s a thriving project (only 31-ish years old, versus C’s 60). The conversation closes on caretakers and the next generation of contributors. Triage, they stress, doesn’t require deep internals knowledge — just reading reports to see if they still make sense is hugely valuable. Security and infrastructure access necessarily stay gatekept for trust reasons, and both agree a bus factor of one (or even two) isn’t good enough. Chris admits he’s struggling to name people who are both nice and know infra. Links from the show: Join us live in Discord — discord.phparch.com Watch live on YouTube — youtube.com/phparch PHP Tek Conference 2027 — Call for Papers now open PHP Arch Swag Store — store.phparch.com Xdebug — and Xdebug Cloud for shared debugging Magazine discount code ALIVE3 — three free months on an annual digital subscription Host: Chris Miller X: @ccmiller2018 Mastodon: @miller@phpc.social Bluesky: @ccmiller2018.bsky.social PHPArch.me: @miller Mike Page Mastodon: @MikePageDev@phpc.social PHPArch.me: @mikepagedev Streams: Youtube Channel Twitch Connect & Hire PHP Architect Website Twitter/X Mastodon Hire PHP Developers Looking to hire PHP developers? Email support@phparch.com – the team is available for consulting, infrastructure work, Ansible playbooks, and code review. Partner This podcast is made a little better thanks to our partners Displace Infrastructure Management, Simplified Automate Kubernetes deployments across any cloud provider or bare metal with a single command. Deploy, manage, and scale your infrastructure with ease. https://displace.tech/ OurCVEs Your security posture, on autopilot with OurCVEs CodeRabbit Cut code review time & bugs in half instantly with CodeRabbit. PHP Architect Consulting Your PHP codebase deserves a partner, not a contractor PHP Architect provides long-term technical partnerships for organizations that need senior-level PHP expertise that you can depend on. https://www.phparch.com/consulting/ Music Provided by Epidemic Sound https://www.epidemicsound.com/ Join Us Live Next Week Youtube Channel Got feedback? Join us on Discord at discord.phparch.com The post PHP Alive and Kicking 2026.08.04 appeared first on PHP Architect.
Leyla Muedin, a registered dietitian nutritionist in New York City, discusses the growing shift from symptom-only “sick care” to a clinically grounded holistic approach to health and recovery. She argues that self-guided wellness routines can leave gaps when underlying medical issues, mental health conditions, substance use disorders, or trauma remain unaddressed, and emphasizes integrating evidence-based clinical evaluation (including labs and deficiency testing) with lifestyle practices. She explains how treating symptoms in isolation misses connections (e.g., stress, sleep, grief) and defines true holistic care as addressing physical, mental, emotional, relational, environmental, and purpose-related factors without rejecting medical treatment. Key components include consistent movement, individualized nutrition built on basics, nervous system regulation (sleep, nature, breathing, meditation/prayer), meaningful social connection, and a sense of purpose as clinically relevant to resilience.
My 25-year-old son has bipolar disorder and can't tolerate his medications. Any natural recommendations?Is chondroitin effective? It's in my collagen capsules, which I take to hopefully reduce wrinklesI believe I am still suffering from the negative effects of COVID. What would you suggest I take?
Is there evidence for statins in the treatment of aortic valve stenosis?How the bacteria behind gum disease can affect heart healthWouldn't it be better to resume taking probiotics after finishing a round of antibiotics?Would it be safe to take olive leaf extract with amoxicillin?I'm considering surgery for varicose veins. Is this just a temporary fix? Can they return?
Benedicte shares her takeaways from the plumbing course. Benedikt goes on a few AWS adventures.Benedicte had so much fun and learned a lot from her plumbing course, even sharing a mindblowing tip of using a balloon to help clear out water from the tap mechanisms during winter. On the work front, their system at Whee! is now live syncing prospects and customers to their email list. Benedicte's also figuring out how to fix the data inconsistency between the bike availability on their website versus the actual availability of bikes at the workshop.The Userlist team reworked their entire data model for themes to support the new stuff. Benedikt also set up a proper CDN for user uploaded assets so there's client side caching. He also took some time to set up Userlist on AWS but is quite unsure if they should move over for good because of the complexity and the unknowns.
What Triggers Age-Related Belly Fat? New Stem Cell Findings and a Nutrition Perspective: Nutritionist Leyla Muedin discusses research from City of Hope (published in Science) on why belly fat increases with age even without major weight gain, emphasizing the health risks of visceral fat as an endocrine organ linked to inflammation, diabetes, heart disease, and accelerated aging. The study suggests aging activates adipocyte progenitor cells (APCs) and produces an age-specific stem cell population called committed preadipocytes (CP-As) that generate new fat cells, with experiments showing older APCs create more fat cells even when transplanted into young mice. Single-cell RNA sequencing identified greater CP-A activity in middle-aged mice and similar cells in higher numbers in middle-aged human tissue. Researchers implicate the LIFR signaling pathway and propose future therapies to block these cells, while Leyla questions root causes and argues metabolic dysfunction—insulin resistance, hyperinsulinemia, high carbohydrate intake, and sedentary behavior—should be addressed nutritionally rather than via a pill.
Nature or nurture—which is more important when it comes to health conditions?Would I benefit from taking nattokinase along with my statin?Mechanism of action of nattokinase vs. statin medications on coronary artery health
My LDL is 421, and I have mild to moderate aortic stenosis. Must I take a statin?Lean Mass Hyper-responders on low carb diets explainedWould you consider writing a book about health in advancing age?A revisit of Dr. Hoffman's published booksWhat is the best dose of lithium orotate for therapeutic benefit?Must I exercise fasted? Why?
Vitamin B12 Deficiency--The “Aging” Symptoms You Shouldn't Ignore: Leyla Muedin, a registered dietitian nutritionist in New York City, discusses vitamin B12 deficiency as a common problem that can mimic normal aging, noting adults need only about two micrograms daily to support red blood cells, nerves, and DNA. She reviews the history of liver treatment for pernicious anemia and explains that deficiency remains common in older adults, vegans/vegetarians, and people with impaired absorption due to low stomach acid, autoimmune gastritis, weight loss surgery, or medications such as metformin and proton pump inhibitors. Symptoms can develop slowly and include fatigue, weakness, shortness of breath, numbness/tingling, poor balance, memory issues, and brain fog; she advises medical evaluation and B12 testing rather than assuming aging or relying on wellness-clinic injections when levels are normal. She emphasizes B12 is primarily in animal foods, so vegans need supplements, and notes broader nutrient shortfalls she sees in vegan clients.
How do I find a preventive cardiologist in northern New Jersey?What is the best supplement for dissolving bone spurs?What is the half-life of vitamin D, either by supplement or sun exposure?What do you think about mushroom coffee? Does it have any health benefits?Please discuss how strontium affects DEXA scan results
Does coffee really dehydrate you? A deeper dive on this important topicHelp for nighttime urinationPlease discuss aortic dissection
Should you panic when your Search Console indexing report is showing pages that aren't indexed? Is a 404 error code always a sign of a broken website? In this episode of Search Off the Record, Martin Splitt and John Mueller from the Google Search Relations team dive deep into the Page Indexing report in Google Search Console. They unpack why treating this report as a static inventory checklist to "fix" things is the wrong response, how to spot massive SEO-ruining hosting or CDN traps, and why a healthy website doesn't actually need a 100% index rate. In this episode, you'll learn: The Indexing Report Shift: Insights from the Search Console team's Hillel on why you should look for trend lines and systemic patterns rather than treating the report as a giant list of errors. When 404s are Good: Why expected 404 errors are technically correct for deleted content, and how to survive the "boss panic" of numbers that won't go down. The Domain Property Advantage: How setting up a domain property handles canonical shifts, www vs. non-www tracking, and performance data much cleaner. The Site Query vs. Search Console: Why the site: query is an artificial tool that might show old domain moves or hreflang swaps for years, making Search Console your only true source of truth. Hosting & CDN Traps: How aggressive bot protections, hidden interstitials, and "Soft 200" error pages completely destroy your crawl data and lead to malicious canonicalization. Discovered vs. Crawled: What it actually means when pages sit in "Discovered/Crawled - currently not indexed," and how to recognize holistic site quality issues over technical bugs. Key Takeaways for SEOs & Developers: Patterns over Inventories: Use the report to verify that your intentional changes (like site migrations or page removals) are processing correctly over time. Forget the Ratio: There is no magic metric for indexed vs. non-indexed pages. Even Google's own developer documentation has a massive chunk of non-indexed content due to intentional choices. Watch Out for Soft Blocks: Ensure your security layers or CDNs aren't serving "Are you a bot?" challenge screens to Googlebot with a 200 success code. Computers Fail (And That's Fine): Minor server blips, failed DNS requests, or temporary 500 errors happen. Google's systems are resilient and will just try again later. Chapters 0:00 - Introduction: The Search Central Live coverage report confusion. 1:45 - Shifting perspectives: Treating Search Console as a pattern tracker, not a checklist. 4:36 - Tracking site migrations and processing data delays. 6:25 - Why 404 errors can be a good thing 8:00 - Handling canonical shifts and the value of Domain Properties. 11:12 - Why the site: query isn't telling you what you think it does (Domain moves and hreflang bugs). 13:38 - CDN bot protection and the absolute nightmare of soft error pages. 17:49 - How to use "marked as fixed". 20:32 - Discovered vs. Crawled Not Indexed: Is it a technical or site quality issue? 25:31 - Debunking the indexed-to-non-indexed ratio myth. 27:48 - Final verdict: How to stop fearing your Indexing Report. Resources Mentioned: Google Search Central: https://developers.google.com/search Google Search Console: https://search.google.com/search-console Search Central Live Events: https://developers.google.com/search/events Are you actively stressing over your non-indexed page counts, or are you tracking the big trend lines? Let us know in the comments! Episode transcript → https://goo.gle/sotr112-transcript Listen to more Search Off the Record → https://goo.gle/sotr-yt Subscribe to Google Search Channel → https://goo.gle/SearchCentral Search Off the Record is a podcast series that takes you behind the scenes of Google Search with the Search Relations team. #SOTRpodcast #SEO #GoogleSearch #SearchConsole Speakers: Martin Splitt, John Mueller
Registered dietitian Leyla Muedin discusses a Frontiers in Microbiology paper suggesting certain probiotics may help sequester heavy metals. The study, sponsored by the Italian company Probiotical and conducted with University of Ghent and University of Piedmont Orientale, researchers used in vitro testing and the SHIME gut simulator to assess Lactiplantibacillus plantarum, Lactobacillus crispatus, and Lactobacillus acidophilus against cadmium, lead, chromium, and mercury. L. plantarum and L. crispatus reduced metal bioavailability primarily in the simulated colonic phase, while L. acidophilus showed minimal detoxification; mercury was least reduced (~10%). An ex vivo mouse-intestine system found probiotic pre-incubation of metals preserved epithelial integrity and reduced inflammatory responses. Leyla notes limitations: corporate funding, only three strains tested, and no in vivo or human trials, though the findings support further animal and clinical research.
You learn at least five new things every episode, and this one stacks them fast. Roll your Apple Watch crown instead of tapping it to keep Sleep mode from searing your eyes, then hit Command-Shift-F in the Finder to jump straight to Recents when a saved file vanishes into the void. When a listener asks how to archive iMessages, you’ll meet iMazing, Shottr’s scrolling screenshots, privacy.apple.com, and a public-key-encryption rabbit hole that explains why even Apple can’t hand your texts back. You’ll also learn to Control-click the Printers list to reset the entire CUPS printing system, and to check every app’s Rosetta versus Apple Silicon status before sluggish performance quietly fools you, because Rosetta survives macOS 27 but finally bows out in fall 2027, so audit those Intel holdouts now. Then the questions roll in. You’ll troubleshoot a PDF that downloads on one Mac but stalls on another (think DNS blocks, CDN handoffs, stale session cookies, and a fast browser swap), wrestle Apple TV lip-sync into line by killing soundbar processing and matching frame rates, and chase a self-dimming iPad back to its ambient-light sensor and screen protector. Cool Stuff Found delivers a Beelink dock that sidesteps Apple’s storage surcharges and Pixette for reviving an ancient iPad as a photo frame. And when refurb Mac minis sell out in two hours and Apple nudges prices up overnight? Don’t Get Caught letting hope prevail like Dave did, grab it the moment you see it, because that cart won’t hold it for you. 00:00:00 Mac Geek Gab 1149 for Monday, July 6th, 2026 July 6th: National Air Traffic Control Day 00:02:47 A quick video from Dave's daughter's wedding MGG Monthly Giveaway – Win a license to Mole Quick Tips 00:00:01 Jan Landy-QT-Roll Your Apple Watch crown in Sleep Mode to go easy on your eyes 00:06:36 Claire-QT-To Find something you just added, Command-Shift-F in Finder for your Recents list 00:11:02 GW-I wish Apple had a way to archive Messages iMazing (and formerly PhoneView) Remember privacy.apple.com 00:19:09 Message in iCloud and Public Key Encryption Shottr's scrolling screenshots 00:23:33 WillRun4Fun-QT-Control-click in Printers list to Reset Printing System Enable CUPS web page on your Mac Visit https://localhost:631/printers/ If that fails, open Terminal and run “cupsctl WebInterface=yes” to enable it 00:26:14 TheDaveAbides-QT-Check your apps’ Rosetta/Apple Silicon status 00:35:28 Andrew-QT-Buy your refurbs immediately…don’t just leave in your cart Refurb Tracker RefurbMe AppTamer Sponsors 00:40:49 SPONSOR: Keeper. Right now, Keeper is offering our listeners 60% off personal and family plans at https://Keepersecurity.com/MGG. This offer is only for podcast listeners! 00:42:10 SPONSOR: Even Realities G2. Use promo code MGG at evenrealities.com to get 10% off Even Ring 1 and/or Even Clip when you add them to your Even G2 order. 00:43:48 SPONSOR: Decagon. Ready to transform your customer support? Decagon helps companies create personalized, concierge-style customer experiences with AI agents across chat, email, voice, and SMS. Go to https://decagon.ai/MGG to get a personalized demo and see what Decagon can do for your team. Your Questions Answered and Tips Shared! 00:45:16 Mike-Why can I download a pdf on ONE computer, but not another? 00:53:01 David-How do I resolve Apple TV lip sync issues? YouTube A/V sync videos AWOL 2500 Projector Sonos Soundbars 01:04:52 Larry-iPad Dims When I don't want it to Cool Stuff Found 01:12:44 Mike-CSF-Belkin Beelink Mac mini storage dock (and others like it) 01:14:24 Greg-CSF-1147-Pixette for displaying photos on an old iPad 01:16:55 MGG 1149 Outtro MGG Monthly Giveaway Bandwidth Provided by CacheFly Pilot Pete's Aviation Podcast: So There I Was (for Aviation Enthusiasts) The Debut Film Podcast – Adam's new podcast! Dave's Business Brain (for Entrepreneurs) and Gig Gab (for Working Musicians) Podcasts MGG Merch is Available! Mac Geek Gab iOS app Mac Geek Gab YouTube Page Mac Geek Gab Live Calendar This Week's MGG Premium Contributors MGG Apple Podcasts Reviews feedback@macgeekgab.com 224-888-GEEK Active MGG Sponsors and Coupon Codes List BackBeat Media Podcast Network
Bone Health Beyond Calcium: Vitamin D, K, Protein, Medications, and Metabolic Risks: Registered dietitian nutritionist Leyla Muedin discusses factors affecting bone health, osteopenia/osteoporosis, and limitations of bone mineral density as a measure of bone strength. She emphasizes optimizing vitamin D via 25-hydroxy D testing (aiming roughly 55–85 and avoiding over 100), ensuring vitamin K for proper calcium placement, and addressing malabsorption from GI conditions, food intolerances, or inflammation. She notes long-term proton pump inhibitor use can impair calcium and magnesium absorption and increase osteoporosis risk. Diet considerations include avoiding overly grain-heavy, acid-forming patterns and ensuring high biological value protein; she also mentions heavy metals affecting bones. Additional assessment includes magnesium and DHEA sulfate, plus resistance and balance training (ideally three times weekly). She highlights research linking hyperinsulinemia/type 2 diabetes/cardiovascular disease to fragility fractures despite normal or higher bone density, proposing carbohydrate restriction, fasting, and ketosis to improve bone remodeling via osteocalcin and mitochondrial function.
Carnivore diet controversiesWhat is a normal oxygen saturation? Mine has been 92-93 lately? Is that okay?
I've worked for many years on my feet and had surgery on both knees. How much glucosamine should I take?Can you discuss oral vs. IV chelation? How do you determine which is appropriate?How important is nitric oxide, and how can I increase mine?Are there any supplements I should stop taking before getting blood tests?
Topics covered in this episode: Free-threaded Python: past, present, and future django-admin-site-search Qwen 3.6 27B is the sweet spot for local development A large batch of PEPs are finalized Extras Joke Watch on YouTube Show Intro Sponsored by us! Support our work through: Our courses at Talk Python Consulting from Six Feet Up Connect with the hosts Michael: Mastodon / BlueSky / X / LinkedIn Calvin: Mastodon / BlueSky / X / LinkedIn Show: Mastodon / BlueSky / X Join us on YouTube at pythonbytes.fm/live to be part of the audience. Usually Tuesday at 7am PT. Older video versions available there too. Finally, if you want an artisanal, hand-crafted digest of every week of the show notes in email form? Add your name and email to our friends of the show list, we'll never share it. Calvin #1: Free-threaded Python: past, present, and future The GIL has prevented true multi-threaded parallelism in CPython since the beginning — multiple past attempts to remove it failed on performance grounds Sam Gross at Meta finally solved it; his work became PEP 703 and ships as free-threaded CPython today Python 3.13 was experimental with 20–40% single-threaded slowdown; 3.14 brought that to 0–10% Python 3.15 (October 2026) delivers a unified ABI — one extension binary works on both GIL and free-threaded builds Already >50% of the top PyPI binary wheels support free threading Wouters predicts free-threaded becomes the default between 3.16–3.20 (2027–2031), with the GIL eventually disappearing next decade Michael #2: django-admin-site-search via Adam Parkin A global/site search modal for the Django admin, by Ahmed Aljawahiry. Hit cmd+k anywhere in the admin and you get a command-palette-style search window, kind of like the one in VS Code. It doesn't just search one model's list page. It searches your entire site in one box: App labels Model labels and field attributes Actual model instances (your data) Two ways to search the instances: model_char_fields (the default): runs an __icontains across every CharField (and subclasses) on the model. Zero config, works out of the box. admin_search_fields: defers to each ModelAdmin's existing get_search_results(), so it respects the search_fields you've already set up. The part I like: it's permission-aware out of the box. Users only see results for the apps and models they actually have view permission on, so you're not leaking anything through search. Results appear as you type, with throttling/debouncing so you're not hammering the server on every keystroke, and it's full keyboard nav: cmd+k to open, up/down to move, enter to go. It's responsive, does dark and light mode, and it pulls Django's built-in admin CSS variables so it just matches whatever admin theme you're running. Under the hood it's Alpine.js, but bundled into static so there's no external CDN dependency. Setup is about what you'd expect: pip install django-admin-site-search, add it to INSTALLED_APPS, mix the AdminSiteSearchView into your AdminSite, and drop a few template includes into base_site.html. Supports Python 3.8 through 3.14 and Django 3.2 through 6.0, MIT licensed, and everything is overridable if you want to skip certain models, add TextField matching, etc. Calvin #3: Qwen 3.6 27B is the sweet spot for local development Qwen 3.6 27B is being called the first local model that genuinely competes as a general-purpose intelligence — benchmarks put it at roughly mid-2025 frontier level (comparable to GPT-5 / Claude Sonnet 4.5) Runs locally via llama.cpp; on an M5 MacBook Max with 8-bit quantization + multi-token prediction, it hits ~32 tokens/sec using ~42GB RAM 4-bit quantization gets it under 18GB, runnable on 32GB devices; Nvidia RTX cards run it even faster The dense 27B is recommended over the faster MoE 35B A3B — author prefers higher quality output over raw speed Privacy and reliability are the pitch: fine-tunable, can't be taken down, suitable for sensitive/proprietary data Author sees this as a stepping stone — frontier open-weight models like GLM 5.2 are now locally runnable with company-grade hardware, and smarter-still local models are coming Michael #4: A large batch of PEPs are finalized A bunch of PEPs went from accepted to final. 668, 687, 691, 699, 701, 703, 728, 770, 773, 829 But this wasn't them making their way into CPython. It's an admin sorta thing. (Thanks PyCoders) See the commit. Extras Calvin: More fun bling for your terminal this time - https://charm.land/ Michael: Follow up from pls, What the pls? Thanks Pito. Joke: BEMoji A production-grade utility and component framework built entirely on emoji class names via Jeff Triplett
Urolithin A (Mitopure) and Mitochondrial Renewal--Muscle, Immune, and Skin Benefits: Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline details urolithin A and Timeline's branded supplement Mitopure. She describes urolithin A's discovery through pomegranate research and worm studies showing a 45% lifespan increase. She discusses human research including improved walking distance and clinical outcomes in muscle endurance and strength. Urolithin A is presented as supporting mitochondrial health by promoting mitophagy—recycling damaged mitochondria—distinct from other mitochondrial supports like CoQ10 and NAD precursors. They explain most people cannot produce enough urolithin A from foods because only 30–40% convert precursors via the microbiome and it would require about six cups of pomegranate juice daily. Dosing discussed is 500–1,000 mg/day via gummies, capsules, or powder, with effects developing over months. She reviews emerging research on immune aging, preclinical work on brain and neurodegenerative conditions, and topical urolithin A for skin.
Dr. Hoffman continues his conversation with Jen Scheinman, MS, RDN, CDN, Director of Science Communications at Timeline.
Vitamin K2 (MK-7) and Coronary Artery Calcification: Insights from a 2-Year Trial: Nutritionist Leyla Muedin discusses a two-year randomized clinical trial in JAMA Cardiology from Maastricht University Medical Center reporting that daily vitamin K2 (menaquinone-7, MK-7) at 360 mcg slowed progression of coronary artery calcification (CAC) in 180 patients with confirmed atherosclerotic cardiovascular disease and baseline CAC 50–400 Agatston units. Compared with placebo, consistent MK-7 use was associated with 29% lower CAC progression and 42% less arterial calcium mass progression, though CAC still increased in both groups; stenosis increases were numerically lower with MK-7 but not statistically significant. Leyla notes many participants were on statins and were smokers, highlighting that statins can raise CAC by stabilizing soft plaque via calcification. The trial suggests MK-7 may slow calcification in newer plaques, may improve arterial elasticity via matrix GLA protein activation, is inexpensive and safe, but clinical event reduction remains unproven; Leyla suggests considering MK-7 (possibly 360 mcg) with vitamin D, magnesium, and dietary measures.
I'm 78 and had a hysterectomy. Is it safe for me to eat tofu or other soy foods?Mitopure joins L'Oreal to create a face cream with Urolithin A.Does taking hyaluronic acid orally cause water retention?Can you discuss ETA contained in New Zealand green mussels?What are your thoughts on using vibration devices to help osteoporosis?
World Cup!What did humans eat from the Ice Age to the Bronze Age?What supplements should I avoid while undergoing radiation therapy for prostate cancer?What is the treatment for sarcoidosis of the lung? Both my friend and his wife have it.
Exam Room Nutrition: Nutrition Education for Health Professionals
Give Nutrition Advice Without Making Patients Feel Punished Have you ever asked, “Do you have any other questions?” at the end of a visit and immediately regretted it?Same.Because of course they have more questions. Important questions. Questions that probably should have been asked 15 minutes ago, except now you're already behind, the next patient is waiting, and you're trying to be compassionate without completely derailing the visit.In this episode, I'm talking with Maya Feller, MS, RD, CDN, registered dietitian, author of Eating From Our Roots, and founder of Maya Feller Nutrition, about the art of inviting patients into treatment instead of simply telling them what to do.We talk about cultural humility, implicit bias, why foods like rice, tortillas, noodles, plantains, and traditional starches get unfairly blamed for chronic disease, and how clinicians can help patients improve blood sugar, blood pressure, and lipids without stripping away the foods that feel like home. Maya also shares a brilliant framework for setting the agenda with patients, asking permission, and keeping the visit patient-centered without losing control of the clock. In this episode, you'll learn: Why “healthy” food is often viewed through an Anglo-American lens, and how that can unintentionally shame patients' cultural foods How to be curious before corrective when talking about nutrition, weight, chronic disease, and food traditions How to use the plate method more flexibly What to say when patients want to improve blood sugar, blood pressure, cholesterol, or inflammation without giving up familiar foods Why frozen meals, canned foods, jarred foods, dried beans, frozen vegetables, and center-aisle foods absolutely belong in realistic nutrition counseling How to help patients reduce added sugar without making it feel like punishment Maya's strategy for “sugar interactions” and helping patients create a beginning, middle, and end around sweets How to start the visit by asking what is on the patient's mind, while still addressing your clinical priorities Resources Mentioned:Episode 146: When Culture is Erased from GuidelinesConnect with MayaAny Questions? Send Me a MessageSupport the showConnect with Colleen:InstagramLinkedInSign up for my FREE Newsletter - Nutrition hot-topics delivered to your inbox each week.Disclaimer: This podcast is a collection of ideas, strategies, and opinions of the author(s). Its goal is to provide useful information on each of the topics shared within. It is not intended to provide medical, health, or professional consultation or to diagnosis-specific weight or feeding challenges. The author(s) advises the reader to always consult with appropriate health, medical, and professional consultants for support for individual children and family situations. The author(s) do not take responsibility for the personal or other risks, loss, or liability incurred as a direct or indirect consequence of the application or use of information provided. All opinions stated in this podcast are my own and do not reflect the opinions of my employer.
Most of us assume that if we look healthy on the outside, our heart is fine on the inside, but today, preventive cardiology dietitian Michelle Routhenstein explains why that's exactly the assumption that gets women into trouble, especially through perimenopause and beyond. We get into the two numbers your doctor probably isn't checking, ApoB and Lp(a), the first five diet changes Michelle makes with clients to bring down high cholesterol numbers, why stretching may be doing as much for your arteries as it does for your joints, and why blood pressure, not HRV, deserves far more of your attention as you move through this life stage. WHAT YOU'LL LEARN ● Why heart disease can silently progress in women who look and feel healthy ● What ApoB and Lp(a) actually measure, and why they matter more than LDL and HDL alone ● The first five diet changes to lower high ApoB or non HDL cholesterol ● Why saturated fat, fiber, and gut health all influence your cholesterol numbers ● Why blood pressure, not HRV, deserves more of your attention in perimenopause ● How menopause hormone therapy really affects your cardiovascular risk ● The minerals your heart needs to keep beating and pumping properly TIMESTAMPS 00:00 Heart Disease Risk in Women: ApoB, Lp(a), and the Tests Your Doctor Isn't Running 10:18 The Hidden Inflammation Driving Your Heart Disease Risk (And How to Test for It) 19:29 The Truth About Saturated Fat and Cholesterol After 40 22:19 The First Five Diet Changes to Lower High ApoB or Non HDL Cholesterol 29:24 Bloating, Gut Health and Thyroid: The Hidden Heart Disease Risks in Perimenopause 39:41 Why Stretching Might Be Protecting Your Arteries, Not Just Your Joints 51:48 Does Menopause Hormone Therapy Actually Protect Your Heart? VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what's actually happening in your body — and how to fix it.
First Phosphate Corp. (CSE: PHOS | OTCQX: FRSPF) just landed a wave of international backing at the 52nd G7 Summit in Évian, France — and CEO John Passalacqua joins MSE to break down what it means for the company's mine-to-market LFP battery supply chain build-out in Quebec. This episode digs into the details of the agreements signed under the Critical Minerals Resilience and Production Alliance, including: • A letter of interest for up to CDN $275 million in guarantees from Denmark's export credit agency (EIFO) to help finance the Bégin-Lamarche mine • LOIs from Italy's SACE, CDP, and SIMEST, alongside engineering group MAIRE, to support First Phosphate's phosphoric acid plant at Port Saguenay using Ballestra technology • A definitive offtake agreement for a minimum of 200,000 tonnes per annum of phosphate concentrate from Bégin-Lamarche • A definitive offtake agreement for a minimum of 60,000 tonnes per annum of phosphoric acid from the Port Saguenay plant John explains how these deals fit into the broader G7 alliance launched by PM Carney in 2025, what each piece of financing and offtake actually de-risks for the project, where things stand on permitting and construction timelines, and why he believes First Phosphate is positioned to lead North America's push for a secure, traceable battery-grade phosphate supply chain. If you're tracking the critical minerals buildout, North American LFP battery supply chains, or First Phosphate specifically, this is a must-watch update straight from the source. 00:00 Intro 00:57 What the G7 Backing Means 02:33 Offtakes and Italy Partnership 04:19 Deal Terms Revenue and Pricing 05:27 Valuation and LFP Market Upside 08:31 Financing and Shareholder Demand 09:57 Timeline Catalysts and Execution 11:56 How the Alliance Came Together 14:07 Treasury and Capital Stack Press releases discussed: https://firstphosphate.com/first-phosphate-g7-investment-offtake-deals/ https://www.pm.gc.ca/en/news/backgrounders/2026/06/17/prime-minister-carney-secures-new-partnerships-defence-and-critical https://www.pm.gc.ca/en/news/statements/2026/06/17/g7-leaders-declaration-securing-supply-chains-critical-minerals https://www.reuters.com/world/asia-pacific/china-defends-critical-minerals-export-controls-after-g7-statement-2026-06-18/ Tickers: CSE: PHOS – FSE: KD0 – OTCQX: FRSPF – OTCQX-ADR: FPHOY Sign up for our free newsletter and receive interview transcripts, stock profiles and investment ideas: http://eepurl.com/cHxJ39 Sponsor First Phosphate pays Mining Stock Education a United States dollar ten thousand per month coverage fee. First Phosphate's forward-looking statement found in the company's presentation applies to the content of this interview. MSE offers informational content based on available data but it does not constitute investment, tax, or legal advice. It may not be appropriate for all situations or objectives. Readers and listeners should seek professional advice, make independent investigations and assessments before investing. MSE does not guarantee the accuracy or completeness of its content and should not be solely relied upon for investment decisions. MSE and its owner may hold financial interests in the companies discussed and can trade such securities without notice. If you buy stock in a company featured on MSE, for your own protection, you should assume that it is MSE's owner personally selling you that stock. MSE is biased towards its advertising sponsors which make this platform possible. MSE is not liable for representations, warranties, or omissions in its content. By accessing MSE content, users agree that MSE and its affiliates bear no liability related to the information provided or the investment decisions you make. Full disclaimer: https://www.miningstockeducation.com/disclaimer/
Sleep, Glymphatic Detox, and the Hidden Heart Risks of Sleep Apnea: Nutritionist Leyla Muedin explains how sleep supports brain “housekeeping” via the glymphatic system, a glial-lymphatic waste-clearance network most active during sleep that moves cerebrospinal fluid through brain spaces to remove metabolites and toxic proteins such as amyloid beta, with sleep deprivation linked to amyloid accumulation. She notes other clearance pathways, including meningeal lymphatic vessels, whose impaired function is associated with neurodegenerative disease and brain injury. Reviews of human studies suggest sleep influences glymphatic outcomes, though results are inconsistent and methods vary. She emphasizes that poor sleep is associated with dementia risk, depressive symptoms, cardiovascular events, mortality, and impaired glucose metabolism, and highlights lifestyle strategies that may improve sleep. She warns that untreated obstructive sleep apnea accelerates cardiovascular aging via intermittent hypoxia and inflammation, raising blood pressure and cardiovascular event risk, while treatment (e.g., CPAP) may halt or reverse damage.
Is there any truth to some of the latest news that claims glucosamine supplements accelerate dementia and Alzheimer's?Some key points on methodology - what were they actually measuring?What does glucosamine have to do with hyperglycosylation?
What may be the real driver of persistent musculoskeletal pain in menopause?What are your thoughts on hyperbaric oxygen for treating hard-to-heal wounds?Kudos to holistic veterinarians!My prostate is Swiss cheese now after so many biopsiesWhat's the latest on melatonin?
Perimenopause, Insulin Resistance, and Persistent Muscle & Joint Pain: A Functional Medicine Framework: Nutritionist Leyla Muedin discusses perimenopausal musculoskeletal symptoms—new or persistent joint pain, muscle aches, and tendon problems—and highlights a Clinician's Journal article by physical therapist Tara Moore proposing insulin resistance screening in perimenopausal musculoskeletal care. She explains that declining estradiol during the menopausal transition can worsen insulin signaling, increase visceral fat, and reduce insulin sensitivity, affecting skeletal muscle recovery and potentially contributing to tendinopathies and poor or short-lived responses to localized treatments like PT. The framework emphasizes assessing systemic metabolic contributors (e.g., sedentary behavior, high-carbohydrate nutrition patterns, PCOS, central weight gain, stress, sleep disruption) and addressing mediators such as inflammation and impaired glucose utilization. She suggests integrating metabolic risk assessment, sleep and stress strategies, resistance training, and interdisciplinary referrals, arguing that nutrition and supplementation—especially a low-carb approach—may improve recovery and pain outcomes.
I do stair climbing indoors in bad weather instead of walking outdoors. Is this worthwhile?The FDA no longer recommends use of radiation shields during X-ray procedures. What say you?I have a queasy stomach feeling, and my blood sugar is higher than usual. What are your thoughts?I've been using magnesium taurate to control palpitations and find I need more than usual.A comment about performance-enhancing drugs in professional sports
Deprescribing thyroid and other meds in older adultsCan I safely take serrapeptase for longer than four weeks?I want to take nattokinase but isn't there a 'clot dislodging' risk?Could you discuss C. difficile and how to treat it?
PHP Podcast – June 11, 2026 Guest Hosts: Sara Golemon, Elizabeth Barron & Holly Schilling Eric and John are out this week — Sara, Elizabeth, and Holly take over. Here’s what they covered: PHPVerse Recap PHPVerse just wrapped up, and Elizabeth was there in Amsterdam. The format is unusual — all speakers are flown to one location, but the audience is entirely virtual. It was a class act: professional TV crew, studio lighting, and a makeup and hair team on site. Around 2,500–3,000 people watched the live stream. Everything was broadcast as one long block; individual talk segments and possibly the documentary trailer will be cut and released separately. The full stream is available now — the PHP documentary trailer (produced by Jet Breeze, covering 30+ years of PHP history) appears around the 2:24:30 mark. PHP Foundation 2026 Strategy Document Elizabeth and the PHP Foundation released their 2026 strategy document the same day as this recording. The foundation gathered community input across numerous conversations and conferences, synthesized it into findings, and has now published a plan for the rest of the year. Key themes: repositioning PHP’s public perception (which Elizabeth calls a solvable problem), creating six special interest groups, and launching an Onboarding Initiative to build a real on-ramp for new PHP developers. Elizabeth’s view is that the two things giving her the most hope for PHP’s future are the passion and expertise of the community, and how good the language itself has gotten. Visit thephp.foundation to read the full document. The Onboarding Initiative One of the six special interest groups the foundation is launching is specifically focused on bringing new developers into PHP. Goals include creating a true learning path (not just a reference manual that assumes existing knowledge), improving educational resources, and potentially working with the php.net website to improve the first-time experience. Holly made the point that PHP’s barrier to entry is genuinely lower than almost any other language — the Hello World program is 11 characters — but that story isn’t being told outside the PHP bubble. New developers are turning to JavaScript as a first language and running into minified spaghetti instead of something approachable. AI Writing PHP — And PHP as a Second Language Holly built the entire PHP Tek conference app backend in Laravel without writing a single line of code herself — AI-generated throughout, which she reviewed and approved. The code held up to peer review at the conference with only minor style nits. She ran it on PHP 8.3 and used modern standards throughout (one piece of feedback: stop using empty()). The consensus: AI models write good modern PHP because of the vast amount of open source PHP they were trained on. The caveat Sara raised is worth thinking about — how much of that training data is PHP 4-era code and WordPress 3 repositories? Either way, Holly’s case for PHP as a second language is strong: low ceremony, low boilerplate, readable syntax, and it’s a language where you can do something useful in minutes. PHP’s Reputation Problem (and Why It’s Fixable) The group dug into PHP’s perception gap — the mismatch between how good the language actually is and how it’s perceived outside the community. Holly’s experience as a mobile developer who recommends PHP to others: the pushback is immediate (“isn’t that slow?”, “isn’t that dead?”). The benchmarks don’t support that reputation — PHP outperforms Python on most comparable workloads — but data alone doesn’t shift perception. Elizabeth’s point is that this is primarily a storytelling and coordination problem, not a language problem, and that the foundation’s repositioning work is exactly aimed at closing that gap. The community has the passion. It just needs to tell the story outside its own bubble. PHP Polling API RFC Sara walked through the RFC for a new Polling API in PHP (wiki.php.net/rfc/poll_API). The short version: PHP currently has five or six different ways to do I/O multiplexing (watching multiple streams and acting on whichever one is ready first), and which one works depends on the OS, available extensions, and PHP version. The Polling API proposal creates a single, unified interface that abstracts all of that. The immediate beneficiaries are async frameworks like Amp PHP, ReactPHP, and Revolt, which currently have to maintain multiple backend implementations to cover different environments. The bigger picture: this is a building block on the path toward true async PHP, likely contributing to something more complete in PHP 9.0. Most app developers won’t use it directly — but the libraries they depend on will. RFCs are all listed at wiki.php.net/rfc. PHP.net: Do As We Say, Not As We Do Sara, who has contributed to php.net, copped to the state of the codebase: some of it dates to the PHP 3 era, there are functions.inc files, and it is very much “do as we say, not as we do.” The historical reason is that php.net used to rely on community-administered mirrors (r-synced servers running everything from PHP 5.1 to 5.6 simultaneously), so modernizing the code was impossible without controlling the runtime. That’s changed with CDN-based load balancing — they can now control what PHP version runs on php.net — and the code has been getting better. But it’s a slow process. PHP Podcasts Past, Present, and Future Holly asked about the PHP Town Hall podcast (Ben Edmonds and Phil Sturgeon), and the group did a quick tour of PHP podcast history. The PHP Roundtable — originally started by Sammy, taken over by Eric — has produced about three episodes. Sara and producer Joe are planning to take it off Eric’s hands and actually do it properly. And Elizabeth announced that the PHP Foundation is launching a new podcast: tentatively called PHP at Scale, hosted by Ben Marx, focused on telling the stories of organizations pushing PHP to its limits. No launch date yet, but there’s already a queue of interested guests. Next Week’s Show — Moved to Wednesday Sara will be on a boat off the coast of Galicia on Thursday, so next week’s episode is moving to Wednesday. Guests will include Paul Reinheimer and (hopefully) Sean Coase — two veterans from PHP’s podcasting past. Elizabeth is going to try to make it work around the Canadian Grand Prix. Mac Mini M4 for Local LLMs Holly picked up a refurbished Mac Mini M4 (16GB RAM, 512GB storage) specifically to run LLM models locally via Ollama. Apple Silicon is a solid choice for this because the unified memory architecture gives the neural cores access to far more RAM than a discrete GPU setup. Sara is waiting for the M5, which is reportedly not coming until fall — and is already resigned to spending too much on it when it lands. Links from the show: PHP Foundation — 2026 Strategy Document PHP RFC: Polling API PHP RFC Wiki — All RFCs Under Discussion Amp PHP — Async framework ReactPHP — Event-driven async PHP Revolt — Event loop for PHP php.net website source code (github.com/php/web-php) PHP Architect Discord Guest Hosts: Sara Golemon Based in Lisbon, Portugal PHP core contributor; code contributor via the Curl project (which means she technically has code on Mars) Elizabeth Barron Executive Director, PHP Foundation Based in Germany Holly Schilling Primary mobile developer; built the PHP Tek 2026 conference app Based near Chicago, IL Streams: Youtube Channel Twitch Connect & Hire PHP Architect Website Twitter/X Mastodon Hire PHP Developers Looking to hire PHP developers? Email support@phparch.com – Joe and the team are available for consulting, infrastructure work, Ansible playbooks, and code review. Partner This podcast is made a little better thanks to our partners Displace Infrastructure Management, Simplified Automate Kubernetes deployments across any cloud provider or bare metal with a single command. Deploy, manage, and scale your infrastructure with ease. https://displace.tech/ PHPScore Put Your Technical Debt on Autopay with PHPScore Music Provided by Epidemic Sound https://www.epidemicsound.com/ Join Us Live Next Week Note: Next week’s show is on Wednesday (not Thursday) with guests Paul Reinheimer and Sean Coase. Youtube Channel Got feedback? Join us on Discord at discord.phparch.com The post The PHP Podcast 2026.06.11 appeared first on PHP Architect.
Eat Strong, Move Smart: Stefani Sassos on Food, Fitness & Health Claims That Matter After 50 The Not Old Better Show, Good Housekeeping, Good Better Best Interview Series
Most of us have had that moment where we get our bloodwork back and shake our heads. We're still our active, health‑minded selves and out of nowhere—rising LDL, ApoB, A1C, and maybe blood pressure and Lp(a), too. This week, preventive cardiology dietitian Michelle Routhenstein joins us to unpack the cardiometabolic chaos and what's really driving it. She explains estrogen's protective role in lipids and blood pressure, why standard risk calculators and even calcium scores can miss women's disease, and which advanced labs are worth asking for. We also dig into how under‑fueling and low‑carb diets can worsen cardiometabolic health and plaque; why complex carbs, fiber, fermented foods, and gut health matter so much; and how to approach protein, red meat, electrolytes, nitric oxide, and statins in a personalized, empowering way—remembering that 80–90% of heart disease remains preventable when women get the right information and advocate for themselves.Michelle Routhenstein, MS, RD, CDCES, CDN is a preventive cardiology dietitian and founder of Entirely Nourished, a virtual practice focused on personalized, science-based nutrition for heart health. With over 14 years of experience, she helps people improve cardiometabolic risk and manage conditions like atherosclerosis, heart failure, and atrial fibrillation using a whole-person approach. She holds Bachelor's and Master's degrees in Clinical Nutrition from New York University, serves on the Forbes Health Advisory Board and the Medical Advisory Committee for the National Menopause Foundation, and is the author of The Truly Easy Heart-Healthy Cookbook and Simple Meal Solutions for High Blood Pressure. Her work has been featured in outlets including Forbes Health, Fox News, Prevention, Women's Health, and Good Housekeeping, and she works with clients virtually from New York via www.entirelynourished.comJoin us at Feisty Fest September 18-20, 2026: https://feisty.co/events/feisty-fest/Sign up for our FREE Feisty 40+ newsletter: https://feisty.co/feisty-40/Learn More about our 2026 Feisty Events, including Bike Camps and Cycling Trips: https://feisty.co/events/Follow Us on Instagram:Feisty Menopause: @feistymenopauseHit Play Not Pause Facebook Group: https://www.facebook.com/groups/807943973376099Support our Partners:Midi Health: You Deserve to Feel Great. Book your virtual visit today at https://www.joinmidi.com/Previnex: Get 20% off your order with code FEISTYBRAIN at https://www.previnex.com/ Wahoo: Use the code FEISTY2026 to get a free Headwind Smart Fan (value $300) with the purchase of a Wahoo KICKR RUN at https://shorturl.at/WVhdrCozy Earth: Use Code HITPLAY at https://cozyearth.com/ for up to 20% off
Nutritionist Leyla Muedin discusses research showing simple strength tests—grip strength and a five-rep sit-to-stand chair test—predict longevity in older women. In a University at Buffalo study of over 5,000 women ages 63–99 followed for eight years, stronger grip and faster chair-stand times were linked to lower mortality; every additional 7 kg of grip strength corresponded to a 12% reduction in death risk, and faster chair-stands were also associated with improved survival, even after adjusting for activity, cardiovascular fitness, and inflammation. She emphasizes prioritizing muscle-strengthening alongside aerobic exercise and suggests accessible resistance options (weights, bodyweight moves, or household items) with professional guidance as needed. She then cites UK Biobank data linking long-term statin use to declines in grip strength and appendicular lean mass, urging discussion with physicians and added vigilance, especially for those also using GLP-1 drugs that may reduce protein intake and muscle mass.
Can topical B12 help relieve itching?The types of doctors to avoidGetting back to basicsA case study of lavender oil helping to relieve itchingYou say you're dairy sensitive but you use whey protein. Please explain.What are your thoughts on a lactose relief patch that is on offer?
Registered dietitian nutritionist Leyla Muedin discusses the growing interest in biological age versus chronological age and explains that biological aging is modifiable through consistent lifestyle choices. She outlines common measurement tools and biomarkers, including epigenetic clocks (DNA methylation), telomere length, VO2 max, inflammatory markers, grip strength, and muscle mass, noting that genetics account for only about 25–40% of biological aging variation. Key interventions include regular aerobic and resistance exercise, protein-adequate nutrition to preserve muscle and prevent sarcopenia (with whey protein and leucine-rich foods noted), improved sleep, stress management, reducing processed foods and visceral fat, and lowering chronic inflammation (CRP, IL-6). She also reviews hormetic stressors such as sauna use and mentions red/near-infrared light and sun exposure without sunglasses. Leyla shares client examples showing biological age can worsen or improve, and encourages repeat testing after lifestyle changes.
Would you discuss vertebroplasty vs. kyphoplasty?I recently had a fundoplication surgery and now have gastroparesisCould you recommend a healthy aging supplement?How to treat Meibomian Gland Dysfunction/dry eye disease?Should we get wool carpeting or hardwood flooring?
An overview of itchingWould tofu be a good addition to my diet?Is TMAO a risk factor for heart disease when eating meat?How about interviewing an expert on vegetarianism?
Nuevo Laredo is one of the most feared cartel cities in Mexico, a place where disappearances, gun battles, and corruption became part of daily life as the Cartel del Noreste, or CDN, tightened its grip on the border. Born from the remnants of the brutal Zetas organization, CDN turned the city into a battlefield, fighting for control of smuggling routes into Texas while allegedly terrorizing civilians, journalists, and anyone seen as a threat. The city became so cartel-corrupted that it dismantled its own police force entirely. The documentary film Spring of the Vanishing adds another layer to the story, documenting how U.S.-trained Mexican marines deployed to fight the Zetas instead carried out their own wave of kidnappings and killings of civilians. Director Andrew Glazer pulls back the curtain on a city where families still search for missing loved ones, and where the line between organized crime and the state itself often seems impossible to separate. Learn more about your ad choices. Visit megaphone.fm/adchoices