Podcasts about roslin institute

Gene-editing technology which makes pigs immune to a highly infectious virus, developed at Edinburgh University's Roslin Institute, has been approved for use by the US Food and Drug Administration. The virus causes a disease called PRRS or Porcine Reproductive and Respiratory Syndrome, which causes premature births in pigs as well as other painful symptoms and costs the pig industry billions. Current legislation doesn't permit its use in the UK. We speak to one of the scientists who's been working on the project for more than seven years.All week we've been taking a closer look at pulses, the dried seeds of crops like beans, lentils and peas, for both human and animal food. In the UK the peas we eat are generally frozen or fresh but dried peas are a major source of protein to millions of people around the world. Scientists at the John Innes Centre in Norwich have been working with researchers in China, the USA and France to uncover the genome of 700 different varieties of pea, from many different countries, to help develop better commercial varieties.The sudden suspension of England's biggest environmental scheme, the Sustainable Farming Incentive, earlier this year was met with horror and disbelief by farmers and environmentalists alike - we preview a special documentary which charts the transition of agricultural policy from the old EU farm subsidy system and the Common Agricultural Policy to the new 'public money for public goods' approach that we have in England today. Presenter = Caz Graham Producer = Rebecca Rooney

In this episode of Talk2TheHand, we dive into the fascinating story of Dolly the Sheep, the world's first animal cloned from an adult cell, and the scientific breakthrough that shook the world. Born in 1996 at the Roslin Institute in Scotland, Dolly wasn't just any sheep—she was living proof that cloning from adult cells was possible, challenging everything scientists thought they knew about biology and genetics. We'll explore the groundbreaking science behind Dolly's creation, including the cloning technique known as nuclear transfer. Hear how scientists like Ian Wilmut and Keith Campbell defied the odds, using a cell from an adult Finn Dorset sheep to produce a healthy, genetically identical lamb. We'll break down the process in simple terms, explaining how Dolly's existence redefined the possibilities of genetic engineering and biotechnology. But Dolly's story isn't just about science—it's about the global reaction that followed. We'll discuss how her birth sparked intense ethical debates, with fears of human cloning dominating headlines and politicians rushing to impose bans. From media frenzy to moral panic, we'll look at how one sheep ignited a worldwide conversation about the future of cloning and what it means to “create” life. We'll also take a closer look at Dolly's life beyond the lab. Despite being a scientific marvel, she lived a relatively normal sheep life, giving birth to lambs of her own. However, her health issues, including early arthritis and lung disease, raised questions about the long-term effects of cloning—questions that scientists are still exploring today. Finally, we'll reflect on Dolly's lasting legacy. How did her creation influence modern science, from stem cell research to genetic therapies? What lessons were learned from her story, and how has cloning technology evolved since? Tune in as we unpack the extraordinary tale of Dolly the Sheep, a fluffy icon who changed the course of scientific history. Talk2TheHand is an independent throwback podcast run by husband and wife, Jimmy and Beth. Obsessed with 90s nostalgia and 90s celebrities, we'll rewind the years and take you back to the greatest era of our lives.   New episodes bursting with nostalgia of the 90s released on Tuesdays. Please subscribe to our podcast and we'll keep you gooey in 1990s love. Find us on Twitter @talk2thehandpod or email us at jimmy@talk2thehand.co.uk or beth@talk2thehand.co.uk

Bird flu is continuing its spread, with an ever growing list of English counties - and the whole of Northern Ireland – now under restrictions which mean all poultry has to be kept indoors. And stricter bio-security measures have been imposed across the whole of the UK.We hear from a farmer in Devon who has had to cull his birds because of a disease outbreak. And the chair of virology at Edinburgh University's Roslin Institute, Professor Paul Digard, discusses the avian flu vaccine situation in the UK and elsewhere.Our theme this week is bulbs - Spring isn't far away! We're with daffodil pickers near Truro in Cornwall.Presenter: Charlotte Smith Producer: Sarah Swadling Farming Today is a BBC Audio Bristol production

RERUN: Dolly The Sheep, the first ever successfully cloned mammal, was introduced to the world's press at the Roslin Institute in Scotland on 22nd February, 1997. Born seven months earlier, with the comparatively unremarkable name ‘Lamb Number 6LL3', news of her birth had been leaked by The Observer before the scientific paper about her genesis could be published, sparking an international frenzy.  In this episode, Arion, Rebecca and Olly ask why the international media (and Bill Clinton) took the opportunity to drum up panic about human cloning, rather than engage with the remarkable breakthrough she actually represented; reveal why Dolly developed a snack habit; and identify a missed opportunity for Dolly's Tea Rooms in Roslin… Further Reading: • ‘Dolly the sheep' (National Museum of Scotland): https://www.nms.ac.uk/dolly • ‘Dolly the Sheep and the human cloning debate - twenty years later' (The Conversation, 2016): https://theconversation.com/dolly-the-sheep-and-the-human-cloning-debate-twenty-years-later-63712 • ‘Retro Report: The Story of Dolly the Cloned Sheep' (The New York Times, 2014): https://www.youtube.com/watch?v=tELZEPcgKkE ‘Why am I hearing a rerun?' Every Thursday is 'Throwback Thursday' on Today in History with the Retrospectors: running one repeat per week means we can keep up the quality of our independent podcast. Daily shows like this require a lot of work! But as ever we'll have something new for you tomorrow, so follow us wherever you get your podcasts: podfollow.com/Retrospectors Love the show? Join 

In 1996, scientists at Roslin Institute of Scotland cloned a sheep and named it Dolly. Dolly was celebrated as the world's first cloned mammal. This event occurred just 3 decades back. But, Indian scriptures, written thousands of years ago, have several references of cloning. The Vedas and Puranas talk about not only animals but also humans that might have been cloned. Some doctors say that the processes and methods mentioned in these books are feasible today. Did ancient Indians know the complex science of cloning? Is human cloning possible, and even necessary? Narrated by Purab Written by Mihir Joshi Audio Design by Aayush Mehra Creative Direction by Dhruv LauSee omnystudio.com/listener for privacy information.

Two cases of avian flu have been confirmed on game farms in Cheshire and Staffordshire, where pheasant and partridge are produced for shooting. Every year more than 40 million partridge and pheasant are released into the wild from game farms, to populate land for shooting. In May the RSPB called for more restrictions on releasing game birds into the countryside, to reduce the risk of new strains of avian flu, but the British Association for Shooting and Conservation says a ban on releases of game birds is not the answer. Sir Ian Wilmut who led the research team that produced Dolly the cloned sheep at the Roslin Institute in Edinburgh, has died at the age of 79. The team used a cell from the mammary gland of a dead adult sheep to create a living animal that was genetically identical to the donor. The work laid the foundations for stem cell research, a technology which aims to cure many of the diseases of ageing by enabling the body to regenerate damaged tissue. All week we're picking out the stories from top-fruit farming - that's apples, pears, plums and cherries. One fruit grower in Kent says he is giving away all his crop to charity, because he says he can't make any money selling it. The Canary Islands have banned imports of UK seed and eating potatoes to their Islands after Colorado beetles were found in potatoes in Kent and Hampshire in July. Each year, the UK exports 50 thousand tonnes of potatoes to Spain, and the Canary Islands are the fourth largest export market for seed potatoes from Scotland. The government's Animal and Plant Health Agency says the Spanish National Plant Protection Organisation has agreed to import potatoes again under new criteria and the APHA is discussing this with the sector. Presenter = Anna Hill Producer = Rebecca Rooney

Welcome to the Instant Trivia podcast episode 721, where we ask the best trivia on the Internet. Round 1. Category: Lose A Turn 1: In 1991, after 8 years as the AKC's top dog, the cocker spaniel lost the No. 1 ranking to this dog called a lab. a Labrador retriever. 2: Chillicothe was this state's capital twice, losing out to Zanesville once and finally to Columbus. Ohio. 3: Only twice between 1949 and 1964 did this team fail to win the American League pennant. the New York Yankees. 4: After a 3-year ride at the top in U.S. sales, this Honda model lost its No. 1 position to the Taurus in 1992. the Honda Accord. 5: This orator was the Democrats' presidential nominee twice, lost a turn and was nominated again in 1908. William Jennings Bryan. Round 2. Category: The French Connection 1: "Acceptez-vous les cartes de credit?" means "Do you accept" these. credit cards. 2: This relative is une tante. Aunt. 3: If you see a sign that says "Non-fumeurs", you're not supposed to do this. smoke. 4: To the French this sport is la natation. swimming. 5: The French call this religious day La Toussaint. All Saints Day. Round 3. Category: Catty Phrases 1: =. =. 2: =. =. 3: =. =. 4: =. =. 5: =. =. Round 4. Category: 19Th Century Fashion 1: Part of the body around which a cravat is worn. the neck. 2: One of the tallest of the top hats; honest Abe was known for his. stovepipe. 3: He put the blue in blue jeans. (Levi) Strauss. 4: A crinoline was used to stretch these garments to about 5 feet wide. skirts (*a dress). 5: Popular styles of these included Hessian, jockey and Wellington. boots. Round 5. Category: Warthogs 1: Roots, grasses, berries, birds' eggs, and even small mammals. eat. 2: A young warthog's canine teeth eventually grow into a pair of these formidable defensive weapons. tusks. 3: Leopards, principally. eats. 4: Warthogs stick this long, thin, tufted body part straight up in the air when they run. their tails. 5: The Roslin Institute of Dolly the sheep fame is putting a warthog gene in domestic pigs to stop ASF, African this fever. swine fever. Thanks for listening! Come back tomorrow for more exciting trivia! Special thanks to https://blog.feedspot.com/trivia_podcasts/

By now, most of us will have heard of GMOs. In case you haven't, GMO stands for genetically-modified organism. This basically means that an organism has had a foreign genetic sequence introduced into it. In theory, this gives the organism certain advantages – it may become hardier by developing a resistance to disease, or in the case of GM food, may be bigger and require fewer nutrients to develop.到目前为止，我们大多数人都会听说过转基因生物。如果你还没有，GMO 代表转基因生物。这基本上意味着一个有机体已经引入了一个外来基因序列。从理论上讲，这给有机体带来了一定的优势——它可能会因为对疾病产生抵抗力而变得更强壮，或者在转基因食品的情况下，它可能更大，需要更少的营养来发育。GM organisms have been used for a while. Scientists in the UK are trialling a GM wheat which allegedly yields40% more crop in greenhouse conditions. GM hens, which are able to lay eggs from different poultry breeds, have been used by scientists in Edinburgh to conserve rare birds by storing their stem cells in a seed bank. And more recently, scientists in China used information from the genome of a plant to increase the production of a key malaria drug, helping to meet the large global demand.转基因生物已经使用了一段时间。英国科学家正在试验一种转基因小麦，据称这种小麦在温室条件下的产量增加了 40%。能够从不同家禽品种产卵的转基因母鸡已被爱丁堡的科学家用来通过将干细胞储存在种子库中来保护稀有鸟类。最近，中国的科学家利用植物基因组的信息来增加一种关键疟疾药物的产量，帮助满足全球的巨大需求。But now scientists at the University of Edinburgh's Roslin Institute have created GE pigs which are allegedly immune to one of the world's costliest livestock diseases. GE stands for gene editing. Unlike GM, gene editing merely alters the DNA of the creature. In this case, a small region of pig DNA was deleted, preventing contraction of the PRRS virus, or Porcine Reproductive and Respiratory Syndrome virus.但现在爱丁堡大学罗斯林研究所的科学家们已经创造出转基因猪，据称这些猪对世界上最昂贵的牲畜疾病之一具有免疫力。GE代表基因编辑。与转基因不同，基因编辑仅仅改变了生物的 DNA。在这种情况下，猪的一小部分 DNA 被删除，从而防止了 PRRS 病毒或猪繁殖和呼吸综合征病毒的收缩。The virus causes breathing problems and death, but even after the GE pigs were exposed to it, none have become ill. And the effect is permanent, so the resistance will be passed on through natural breeding. Tests so far showed that the animals are not weakened in any other way by the process, claims Research leader Dr Christine Tait-Burkard. "The main thing that this edit will do is benefit animal welfare because the animals will not get a devastating disease."这种病毒会导致呼吸困难和死亡，但即使在转基因猪暴露于病毒之后，也没有人生病。而且效果是永久性的，所以抵抗力会通过自然繁殖传递。研究负责人克里斯汀·泰特-伯卡德博士声称，迄今为止的测试表明，这些动物并没有因为这个过程而以任何其他方式被削弱。“这次编辑将做的主要事情是有利于动物福利，因为动物不会患上毁灭性疾病。”However, critics have argued that the creature's welfare will actually suffer because of this. Helen Browning of the Soil Association believes this only addresses the symptom of the problem and not the root cause. "It is not encouraging companies to change the way they keep their pigs so they don't become diseased in the first place", she says.然而，批评人士认为，这种生物的福利实际上会因此受到影响。土壤协会的海伦布朗宁认为，这只能解决问题的症状，而不是根本原因。她说：“这并不是在鼓励公司改变养猪的方式，以免它们一开始就生病。”Regardless, this is an experiment and while the technique appears to work, it is several years away from regulation and implementation. “On top of that, only if these studies are successful and the public are accepting, would we integrate these gene edits into commercial breeding stocks," Dr Tait-Burkard told the BBC. So it seems we may have a while yet.无论如何，这是一个实验，虽然该技术似乎有效，但距离监管和实施还有几年的时间。“最重要的是，只有当这些研究成功并且公众接受时，我们才会将这些基因编辑整合到商业育种中，”Tait-Burkard 博士告诉 BBC。所以看来我们可能还有一段时间。词汇表genetically-modified 转基因的organism 生物体genetic sequence 基因序列hardy 强壮的resistance to disease 抗病nutrient 营养物，养分trial 试验stem cell 干细胞genome 染色体组，基因组drug 药物immune 有免疫力的DNA 脱氧核糖核酸contract a virus 感染一种病毒reproductive 繁殖respiratory 呼吸的syndrome 综合症expose to (a virus) 感染（一种病毒）pass on 传下去，遗传给...symptom 症状

Dolly The Sheep, the first ever successfully cloned mammal, was introduced to the world's press at the Roslin Institute in Scotland on 22nd February, 1997.Born seven months earlier, with the comparatively unremarkable name ‘Lamb Number 6LL3', news of her birth had been leaked by The Observer before the scientific paper about her genesis could be published, sparking an international frenzy. In this episode, Arion, Rebecca and Olly ask why the international media (and Bill Clinton) took the opportunity to drum up panic about human cloning, rather than engage with the remarkable breakthrough she actually represented; reveal why Dolly developed a snack habit; and identify a missed opportunity for Dolly's Tea Rooms in Roslin…Further Reading:• ‘Dolly the sheep' (National Museum of Scotland): https://www.nms.ac.uk/dolly• ‘Dolly the Sheep and the human cloning debate - twenty years later' (The Conversation, 2016): https://theconversation.com/dolly-the-sheep-and-the-human-cloning-debate-twenty-years-later-63712• ‘Retro Report: The Story of Dolly the Cloned Sheep' (The New York Times, 2014): https://www.youtube.com/watch?v=tELZEPcgKkEEnjoyed this episode? There's FIVE MINUTES of bonus content about Dolly The Sheep for you to download, exclusively available to our Subscribers on Apple Podcasts and our supporters* on Patreon (patreon.com/Retrospectors). Sign up now, support our show and get bonus content each and every week!* top two tiers onlyFor bonus material and to support the show, visit Patreon.com/RetrospectorsWe'll be back tomorrow! Follow us wherever you get your podcasts: podfollow.com/RetrospectorsThe Retrospectors are Olly Mann, Rebecca Messina & Arion McNicoll, with Matt Hill.Theme Music: Pass The Peas. Announcer: Bob Ravelli. Graphic Design: Terry Saunders. Edit Producer: Emma Corsham.Copyright: Rethink Audio / Olly Mann 2022.#90s #Science #Invention #Discoveries #UK See acast.com/privacy for privacy and opt-out information.

É il 1996, in una calda giornata di inizio luglio, nei laboratori del Roslin Institute di Edimburgo in Scozia, viene al mondo la pecora Dolly, Il primo essere vivente nato grazie alla scienza ed all'ingegno umano. Dolly, nome affibbiatole in onore della cantante country americana, Dolly Parton, entra nella storia, oltre che nei trattati di biologia, in quanto primo mammifero creato con successo attraverso la clonazione. Dall'altra parte dell'oceano Atlantico l'intero mondo della musica piange la scomparsa di Lesane Parish Crooks meglio conosciuto con il nome di Tupac Amaru Shakur, anche qui dovremmo aprire un capitolo a parte solo per la genesi del suo nome, ma non lo faremo… Il famoso rapper rimane vittima di un agguato mentre si trovava sulla sua auto per le strade di Las Vegas, morendo a soli 25 anni. E in ambito punk hardcore?---------------------------------------------PUNKCAST--------------------------------------------------------Punkcast è un podcast DIY che parla del mondo hardcore punk a 360 gradi, lo puoi ascoltare e scaricare sulle principali piattaforme di podcasting e qui su YouTube. Iscriviti al mio canale e attiva gli avvisi per rimanere sempre aggiornato.----------------------------------------------PODCAST---------------------------------------------------------SPREAKER https://www.spreaker.com/show/punkcast_1APPLE PODCAST https://podcasts.apple.com/it/podcast/punkcastSPOTIFY https://open.spotify.com/show/4akW3E2aGvE6OCT1PJ0LlT?si=WUAUhBxoQ4yMjHUXdMd2_AGOOGLE PODCAST https://podcasts.google.com/?feed=aHR0cHM6Ly93d3cuc3ByZWFrZXIuY29tL3Nob3cvNDM3MDg5NS9lcGlzb2Rlcy9mZWVk--------------------------------------LIVE STREAM-----------------------------------------------------------TWITCH www.twitch.tv/punkcast_podcastSostieni PUNKCAST con un abbonamento. Se hai AMAZON PRIME, connettilo al tuo account Twitch ed avrai un abbonamento GRATUITO ogni mese con cui supportarmi. Abbonarti al mio canale è gratuito, ti eliminerà le pubblicità di twitch e ti darà nuove funzionalità.-------------------------------------SOCIAL NETWORK----------------------------------------------------INSTAGRAM https://www.instagram.com/punkcast_podcastINSTAGRAM https://www.instagram.com/ale18021981FACEBOOK https://www.facebook.com/Punkcast-112546450493378TIK TOK https://www.tiktok.com/@punkcast?lang=it-IT-----------------------------------------------------------------------------------------------------------------------

Nile tilapia are the third most important farmed fish worldwide, but the emergence of the Tilapia Lake Virus (TiLV) threatens its sustainable production. In this episode, Dr Agustin Barría (The Roslin Institute) discusses his recent collaboration, where they used a natural outbreak of TiLV to investigate the genetic architecture of disease resistance. In this episode we explore the recent Heredity paper: “A major quantitative trait locus affecting resistance to Tilapia lake virus in farmed Nile tilapia (Oreochromis niloticus)” https://www.nature.com/articles/s41437-021-00447-4 See acast.com/privacy for privacy and opt-out information.

Das weltweit erste Klonschaf Dolly wurde im Sommer 1996 geboren. Erst im Februar 1997 wurde die Existenz von Dolly bekannt. Erschaffen wurde Dolly von schottischen Wissenschaftlern und löste eine breite öffentliche Debatte über das Für und Wider der Gentechnik an.  2003 wurde das sechs Jahre alte Schaf wegen einer fortschreitenden Lungenerkrankung eingeschläfert. Ihre Schöpfer am Roslin Institute in Schottland sagten, dass es keinen Zusammenhang gebe zwischen Dollys Erkrankung und der Tatsache, das sie geklont sei. Die Lungenkrankheit unter der Dolly litt, sei üblich bei Schafen höheren Alters. Die Viruserkrankung sei durch ein anderes Schaf im selben Stall übertragen worden. Das Klonschaf Dolly hat seine letzte Ruhestätte im schottischen Nationalmuseum in Edinburgh. Hier wurde das Schaf ausgestopft und steht jetzt auf einem strohbedeckten Sockel. Das Klonschaf stiess eine Debatte rund um die Gentechnik an, die bis heute anhält.  Gast:  * Irène Dietschi, SRF Wissenschaftsredaktorin 

The parasite Trypanosoma brucei is transmitted via tsetse flies. It causes a disease known as trypanosomiasis or sleeping sickness in humans, but in cows, it's known as nagana or animal African trypanosomiasis. In this episode, Joan Cortada García interviews Maria Contreras-Garcia from The Roslin Institute on her work to validate and characterize the use of a small RNA as a diagnostic test for trypanosomiasis.Here is a link to the event mentioned by Ruby White in our episode coda.  The event is a joint University of Edinburgh and University of Sydney Workshop Series on sustainable food production, antimicrobial resistance and One Health https://www.eventbrite.com.au/e/university-of-sydney-and-university-of-edinburgh-joint-workshop-series-2021-tickets-142438833385?utm_campaign=2889898_UoE-UoSyd%20OH%20workshops%20EID&utm_medium=email&utm_source=College%20of%20Science%20%26%20Engineering%2C%20The%20University%20of%20Edinburgh&dm_i=2MP0,1PXUY,9QQ8JI,5VOLI,1

Dan Saladino looks at the future role of genome editing in food and farming. A public consultation is underway on technologies such as CRISPR. What could it mean for farmers and consumers? Unlike transgenic technologies (in which DNA is moved from one species to another), genome editing can be used to create changes to the DNA of plants and animals within a species. Helping to explain how the technology works is a plant biologist working at Cold Spring Harbour in the United States, Zach Lippman. He's using CRISPR to create new types of tomato plants, some of which are higher yielding, more compact and better suited to urban agriculture. Meanwhile, Dr Mike McGrew, a molecular biologist based at the Roslin Institute in Scotland describes how genome editing might help result in future breeds of chickens that are completely resistant to avian influenza, a serious problem for all forms of poultry production. The public consultation has been prompted by the UK government's desire to change the legal status of genome editing. At present, because of a decision by the European Court of Justice back in 2018, the technology is as strictly regulated as all other forms of genetic modification. Brexit makes it possible to diverge from the EU's position. Lawrence Woodward of the campaign group Beyond GM has concerns over the process. For such a powerful technology, one that could potentially transform the future of food and farming, he argues we need a much bigger public debate. Farmer Guy Watson of Riverford Organic and Philip Lymbery of Compassion in World Farming both fear the technology will result in more intensive, industrial forms of production. Gideon Henderson, DEFRA's Chief Scientific Adviser gives his response. Produced and presented by Dan Saladino.

Today's storyteller is Pat Lennard! He's a PhD student at Leiden University in the Netherlands and from Tasmania. His background is in biotechnology, One Health, and infectious diseases. We start this episode talking about his work with Tasmanian Devils and their transmissible cancer called the Devil Facial Tumor Disease (also known as DFTD). His work with DFTD introduced him to infectious and transmissible diseases and OneHealth. I had never heard of OneHealth but it's basically this idea (and related organizations) that environmental, human, and animal health are all interrelated and connected, and so people from a variety of backgrounds are working on all fronts towards a common goal. Anyway this is a fun chat so enjoy! --- You can find Rachel Villani on Twitter @flyingcypress and Storytellers of STEMM on Facebook and on the shiny new Twitter account @storytellers42. You can find Pat Lennard on Twitter @prlennard and on his website: https://www.patricklennard.com/. The Roslin Institute: https://www.ed.ac.uk/roslin The World Health Organization (WHO) info about OneHealth: https://www.who.int/news-room/q-a-detail/one-health Wikipedia info about OneHealth: https://en.wikipedia.org/wiki/One_Health Episode referred to: Ingrid Albion (Episode 26) about Tasmanian Devils (plus more wildlife work/legacy programs) Book List: Viva la Revolucion by Eric Hobsbawm Recorded on 16 January 2021.

Join Safeer Zartasht Khan and Rabeeb Mirza for Tuesday's show where we will be discussing:Genetic Editing/Philosophy behind crime and punishment Genetic Editing: Livestock and Food crops The UK could soon legalise gene editing of crops and livestock for consumption, potentially revolutionising the farming industry. Join us LIVE from 4pm as we discuss this whilst reflecting on concerns from animal welfare groups. The Philosophy Behind Crime and Punishment Islam is not only a religion but also a civilisation and social order based upon revealed principles. Therefore, there are clear guidelines on civil behaviour and how it should be enforced. Join us LIVE from 5pm as we consider the philosophy of crime and punishment in Islam. Guests include: Professor Dale Sanders: (Director of the John Innes Centre) Dr Mike McGrew: (A group leader at The Roslin Institute, UK) Dr Sarah Davidson Evanega: (Director of the Alliance for Science) Sir Dr Iftikhar Ahmad Ayaz KBE, OBE: (Honorary Consul for Tuvalu, Chairman International Human Rights Committee) Produced by: Ruhi Yaqub, Arub Anwar and Iffat Mirza

In the new EU-UK deal, the UK is to be an associate member of the latest EU research funding round, known as Horizon Europe. costing around £2bn to take part, what can UK scientists now do and what has changed? UKRI CEO Otteline Leyser and the Wellcome Trust EU specialist Beth Thompson discuss ways in which UK researchers are breathing a sigh of relief. Of all the things the UK can now diverge from the EU, DEFRA is currently holding an open consultation on whether to tweak the current GMO regulations so as not to include CRISPR style Genetic Editing. The EU is coincidentally looking at the same issue. John Innes Centre's Janneke Balk works on making strains of wheat that have a higher level of iron for nutrituiional fortification. Interim head of the Roslin Institute in Scotland Bruce Whitelaw thinks developing disease resistance in farm animals is potentially profitable area. Both agree the GMO regulations should be more tightly specified to bring clarity and opportunity for innovation. In Iceland, Kari Stefansson's company Decode Genetics analyse the genetic codes of most of the population of Iceland. This has allowed them to look at the parents, siblings, and offspring of identical twins, and identify how early genetic differences between them develop. And it's very early indeed. Given that identical twins studies are so often used to address issues surrounding the so-called Nature-vs Nurture debate, the findings, published in the Journal Nature, are striking. Presenter by Marnie Chesterton Produced by Alex Mansfield Made in association with the Open University.

The FDA may be days away from approving another coronavirus vaccine. Dr. Shane Crotty from the La Jolla Institutes of Immunology explains how the Moderna vaccine works. The debate over whether to vaccinate prison inmates is heating up. Former U.S. Attorney General Alberto Gonzales weight in. The FDA approves the first, over-the-counter home test for the coronavirus. Dr. Bruce Tromberg breaks down what we know about the new test so far. Researchers say people with certain genes may be more susceptible to getting a severe case of COVID-19. Dr. Konrad Rawlik from the University of Edinburgh's Roslin Institute decodes the latest findings.  To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices

The FDA may be days away from approving another coronavirus vaccine. Dr. Shane Crotty from the La Jolla Institutes of Immunology explains how the Moderna vaccine works.  The debate over whether to vaccinate prison inmates is heating up. Former U.S. Attorney General Alberto Gonzales weight in.  The FDA approves the first, over-the-counter home test for the coronavirus. Dr. Bruce Tromberg breaks down what we know about the new test so far.  Researchers say people with certain genes may be more susceptible to getting a severe case of COVID-19. Dr. Konrad Rawlik from the University of Edinburgh's Roslin Institute decodes the latest findings.  Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this episode, guests Claire Askew and Rowland Kao chat about vintage stuff, lost meanings and viral transmission.Claire is an award-winning poet and novelist. Her debut novel, 'All the Hidden Truths', featuring the character DI Birch, won the 2016 Lucy Cavendish Fiction Prize as a work in progress, and was selected as a Times Crime Book of the Month. The second novel in the DI Birch series, 'What You Pay For' was published in August 2019 and the latest, 'Cover Your Tracks', came out this summer. Rowland is Chair of Veterinary Epidemiology and Data Science at the Roslin Institute, part of the University of Edinburgh. He is a member of the Science Advisory Council at the Department for Environment, Food and Rural Affairs (DEFRA) and is working with Public Health Scotland on coronavirus modelling.Each episode of Sharing things is a conversation between two members of our university community. It could be a student, a member of staff or a graduate, the only thing they have in common at the beginning is Edinburgh. We start with an object. A special, treasured or significant item that we have asked each guest to bring to the conversation. What happens next is sometimes funny, sometimes moving and always unexpected. Find out more at www.ed.ac.uk/sharing-things-podcast

Why do some people get more sick than others? The answer could lie in our genes. In this episode we talk to Max Fourman, who is part of the Baillie Lab run by Dr Kenneth Baillie, and based at the Roslin Institute at The University of Edinburgh. They use genomics - the sequencing, study, and mapping of the genome - to search for the genes that make some people more susceptible to disease. The lab is using this knowledge to study COVID-19, leading a large, collaborative, open-source research study called GenOMICC (the Genetics Of Mortality In Critical Care) to try and understand why some people are more severely affected by SARS-CoV-2. Not Another Science Podcast is edited by Helena Cornu, hosted by Tom Edwick and brought to you by Edinburgh University Science Magazine (EUSci). Our podcast logo was designed by Apple Chew. Visit our website at www.eusci.org.uk to check out the latest issue of the magazine, a ton of other cool science content by our student journalists, and to see how to get involved. All podcast episodes and transcripts can be found at www.eusci.org.uk/podcasts/. Music by Kevin Macleod: https://incompetech.filmmusic.io/song/3788-funkorama; https://incompetech.filmmusic.io/song/3787-funk-game-loop http://creativecommons.org/licenses/by/4.0

In today's episode, we have a special guest: Dr Christine Tait-Burkard. She has tenure at the Roslin Institute and shares with us both the experiences as a student but also as a student supervisor

Professor Jean Manson is Head of the Neuropathogenesis Division of The Roslin Institute at the University of Edinburgh. This lecture is part of the Medical Detectives, a series of public lectures that show how keen detective work is still essential for 21st century doctors: http://www.ed.ac.uk/news/events/medical-detectives/ Recorded on 4 October 2012 in the Anatomy Lecture Theatre at the University of Edinburgh.

Trophy hunters are always after the lion with the largest darkest name and the stag with the most impressive antlers. Research by Rob Knell at Queen Mary University of London finds that removing a small proportion of these top males can drive whole populations to extinction, if their environment is changing. Gene drive is a new genetic technology that could be used to eradicate populations of species of 'pest' animals. The Roslin Institute in Edinburgh has just announced it is to begin research on gene drives to control rat and mouse populations. The Institute's Bruce Whitelaw and Simon Lillico explain how the approach would work and argue that it would be humane compared to traditional methods of vermin control. However there are concerns about its potential ecological consequences - namely the risk of female infertility in the targeted species spreading without no geographical limits. Kevin Esvelt of MIT voices his reservations. Bruce Whitelaw outlines how future research aims to bring gene drives under more control. Researchers in the USA and Japan talk about their discovery of nuclear reactions in lightning strikes, and Caroline Brighton and Graham Taylor of the University of Oxford explain why they have been attaching small cameras and GPS units to peregrine falcons and recording the birds chasing drones.

The African Swine Fever Virus is a devastating pathogen that leads to fatal disease in domesticated swine.  Scientists at the Roslin Institute led by Prof. Bruce Whitelaw have made an important advance for domestic pig [...] The post 037 Gene Editing Virus Resistant Pigs first appeared on Talking Biotech Podcast.

There is a new genetic technology which promises to revolutionise agriculture and transform our influence over the natural world. Research is well underway to create pigs and chickens immune to pandemic influenza, cereals which make their own fertiliser and mosquitoes engineered to wipe out wild populations of the insects which transmit diseases to humans. These are just three examples of what we could create with CRISPR gene editing. Should we be worried about this unprecedented power over animals and plants? The potential for good is enormous. The ethical challenges are profound. Professor Matthew Cobb of the University of Manchester explores the brave new world of CRISPR gene editing. (Photo: Pigs at the Roslin Institute that have been gene-edited with the goal of making them resistant to African Swine Fever virus)

Diseases devastate livestock around the world. In chickens for example the deadly strain of bird flu and the lesser known bacterial infection Campylobacter, not only harms the chickens but is also a real threat to human health. Melissa Hogenboom visits one of the world's leading genetics institutions, the Roslin Institute in Edinburgh in the UK and hears about new genetic techniques to combat diseases in our livestock. In chickens, professor Helen Sang uses a subtle form of genetic modification, called genome editing. Her team is trying to find the genetic components of natural resistance in a wide group of chicken breeds, which they can then insert into the genome of livestock fowl in the hope of breeding healthier, safer chickens. They are close to making disease resistant birds but they are aware that GM animals are still a long way from entering the market in Europe. Similar research is going on in cows for TB resistance, but here instead of genetically modifying they are cross-breeding which may take ten or more generations to complete. Melissa hears from Professor Liz Glass who studies the genetics of disease resistance in cattle. Her work has applications in the design of better vaccines for infectious diseases and understanding how disease spreads. Melissa also hears about a team creating a frozen bio-bank of bird stem cells - cryopreserving them so that they could one day resurrect entire breeds. This technique could provide hope against losing these valuable genes forever. Producer and presenter: Melissa Hogenboom (Photo: Chickens. BBC copyright)

Dinosaur A jumble of bones found in Venezuela belong to a group of very early dinosaurs, that could have been herd animals. Paul Barrett from the Natural History Museum explains to Professor Alice Roberts how a jumble of bones found in a 'bone bed' belong to a number of individual Laquintasaura venezuelae dinosaurs. They are an ancient, small, omnivorous dinosaur, which could have survived the Tertiary/Jurassic extinction event 200 million years ago. Genetically Editing Chickens Diseases devastate livestock around the world. In chickens for example the deadly strain of bird flu and the lesser known bacterial infection Campylobacter, does not only harm the chickens but is also a real threat to human health and welfare. Scientists are continually trying to develop vaccines, but the strains of bacteria keep evolving resistance to them. One of the solutions being explored at the Roslin Institute in Edinburgh, is genetic. Using a subtle form of genetic modification, called genome editing. The team are trying to find the genetic components of natural resistance in a wide group of chicken breeds, which they can then insert into the genome of livestock fowl in the hope of breeding healthier, safer chickens. Lightning A listener asks why lightning is jagged. Rhys Phillips from Airbus Group in Cardiff makes lightning in a lab. He has the answer. Rosetta The European Space Agency's robotic spacecraft Rosetta has reached the orbit of the comet Churyumov-Gerasimenko, and is about to start its detailed study. In the audacious and risky mission, the craft will follow the orbit of the comet as it approaches and passes the Sun. It will attempt to land a probe on the surface of the icy, rocky mass. It's hoped the mission will provide great insight into what comets are made of, how they behave as they heat up, creating its gassy coma and tail. And it's hoped Rosetta and its lander will be able to tell about where Earth's water and even some of the building blocks for life might have come from. Diatoms A type of phytoplankton, found in water, called Diatoms build hard silicon-based cell walls. Researchers, at the University of Galway, have shown it's possible to chemically transform the shells of living diatoms so they could carry drugs into our bodies in entirely new ways. Producer: Fiona Roberts.

Pennie Latin is in conversation with Professor Helen Sang from the Roslin Institute. She hears about Helen's work with genetically modified chickens which could lead to the eradication of bird flu, the provision of food for the world's growing population and the production of drugs to treat diseases like cancer.

Professor Jean Manson is Head of the Neuropathogenesis Division of The Roslin Institute at the University of Edinburgh.This lecture is part of the Medical Detectives, a series of public lectures that show how keen detective work is still essential for 21st century doctors: http://www.ed.ac.uk/news/events/medical-detectives/Recorded on 4 October 2012 in the Anatomy Lecture Theatre at the University of Edinburgh.

Professor Jean Manson is Head of the Neuropathogenesis Division of the Roslin Institute at the University of Edinburgh. A prion is an intriguing and unique killer that became infamous in the UK when it attacked in the guise of Bovine Spongiform Encephalopathy (BSE), more commonly termed “mad cow disease”. The prion, though, does not restrict its victims to cattle; it has attacked many different species including sheep, cows, goats, deer and humans. It moves between species, as occurred with BSE passing from cows to humans in the form of variant CJD. Once it infects its victim it slowly, sometimes after many years, reaches the brain and destroys nerve cells, the neurones, and leads to death because the brain can no longer function to keep the body alive. Medical detectives have spent years trying to solve the case of this elusive killer: how does it select its victim, does it have multiple identities and how do its actions finally lead to death? This talk will take a journey through those investigations, lay out the evidence and show how understanding the elusive prion may allow a much greater insight into other neurodegenerative diseases such as Alzheimer’s disease. This lecture is part of the Medical Detectives, a series of public lectures that show how keen detective work is still essential for 21st century doctors: http://www.ed.ac.uk/news/events/medical-detectives/ Recorded on 4 October 2012 in the Anatomy Lecture Theatre at the University of Edinburgh.

Melvyn Bragg and guests discuss the implications of the developments in genetic engineering. Out of the city of Cambridge in the mid century came DNA and out of Edinburgh at the end of the century came the cloning of Dolly the sheep. These two facts might well do more to change the world literally, and our view of the world, than anything else that has happened at any time. Genetics have become the conversation of our day and with the Human Genome Project lumbering towards completion, its power grows. But are the consequences likely to be destructive and will what we think of as a human being, a personality, or even a person, change uncomfortably and irredeemably? With Grahame Bulfield, geneticist, honorary professor, Edinburgh University and Director of the Roslin Institute, Edinburgh; Bryan Appleyard, features writer for The Sunday Times and author of Brave New Worlds: Genetics and the Human Experience.

Melvyn Bragg and guests discuss the implications of the developments in genetic engineering. Out of the city of Cambridge in the mid century came DNA and out of Edinburgh at the end of the century came the cloning of Dolly the sheep. These two facts might well do more to change the world literally, and our view of the world, than anything else that has happened at any time. Genetics have become the conversation of our day and with the Human Genome Project lumbering towards completion, its power grows. But are the consequences likely to be destructive and will what we think of as a human being, a personality, or even a person, change uncomfortably and irredeemably? With Grahame Bulfield, geneticist, honorary professor, Edinburgh University and Director of the Roslin Institute, Edinburgh; Bryan Appleyard, features writer for The Sunday Times and author of Brave New Worlds: Genetics and the Human Experience.