Genus of Gram-negative bacteria
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Could Chicken Be Linked to Rising Colon Cancer Rates?
We're in Liverpool this week, hosting our annual conference and meeting our members, collaborators and authors.We know that there will be a lot of exciting conversations, interesting presentations and vital networking opportunities happening all over the and wanted to make sure you could keep the excitement going even after the events of the day have finished.So, across the four days of annual conference we'll be bringing you mini episodes of Microbe Talk, each featuring a presenter from the programme.For the second episode of our miniseries for Annual Conference Clare spoke to Elizabeth O'Gorman about her research titled ‘Adaptation of Campylobacter to Sodium Chloride Alters Phenotypes Associated with Human Disease' which she will be presenting at the infection forum tomorrow afternoon. Elizabeth and Clare chat about food safety and how consumer trends might be altering the of bacteria on our meat.
Send us a textDr. Jessica Sacher, Ph.D. is Co-Founder of Phage Directory ( https://phage.directory/ ), a global network of phage researchers from more than 80 countries, where she directs its phage-sourcing and community-building efforts, including coordinating over 50 phage-finding efforts, where a network of more than 1,300 members of the global phage community volunteer their time and lab space to identify active phages for patients.Dr. Sacher is also a Staff Scientist at Stanford University School of Medicine ( https://profiles.stanford.edu/jessica-sacher ) in Dr. Paul Bollyky's lab where she leads strategy & lays groundwork for a new phage-based therapeutic development and delivery center at Stanford, developing manufacturing processes and quality control pipelines for clinical-grade phage biologics, as well as evaluating phages as gene and peptide delivery vectors for eukaryotic and microbial cells.Dr. Sacher was previously a member of Prof. Jon Iredell's group in Sydney, Australia as a postdoctoral research scientist for the Phage Australia project where she developed and streamlined Phage Australia's phage selection, biobanking, and manufacturing process, to make phage therapy available for patients Australia-wide and eventually beyond.Dr. Sacher received her PhD in Microbiology and Biotechnology in 2018 from the University of Alberta, Canada.Dr. Sacher is also Founder, Editor, Writer of Capsid & Tail: the phage community newsletter, a weekly report on bacteriophage news and researchImportant Episode Links - Bacteriophage therapy for multidrug-resistant infections: current technologies and therapeutic approaches - Published March 3, 2025 - The Journal of Clinical Investigation -https://www.jci.org/articles/view/187996The Citizen Phage Library (https://citizenphage.com) #JessicaSacher #PhageDirectory #Bacteriophage #StanfordUniversity #Campylobacter #SteffanieStrathdee #Microbiology #PhageBiobank #Biofilms #AMR #AntimicrobialResistance #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show
In this special International Women's Day episode of The Poultry Nutrition Blackbelt Podcast, Dr. Shijina Rajan explores the role of caprylic acid as an alternative to antibiotics in poultry production. She discusses its antimicrobial properties, its impact on Salmonella reduction, and its application in pre and post-harvest interventions. Listen now on all major platforms!"Caprylic acid, a medium-chain fatty acid, has strong antimicrobial properties that could help reduce foodborne pathogens in poultry production."Meet the guest: Dr. Shijina Raj Manjankattil Rajan is a postdoctoral research fellow at Auburn University's Department of Poultry Science. She holds a Ph.D. and M.S. in Animal Sciences from the University of Minnesota and a DVM from Kerala Veterinary & Animal Science University. She is a PSA member and her research focuses on antibiotic alternatives for poultry, targeting major foodborne pathogens like Salmonella and Campylobacter.Click here to read the full research article!What you'll learn:(00:00) Highlight(01:05) Introduction(04:59) Caprylic acid explained(06:35) Pre-harvest studies(07:34) Impact on Salmonella reduction(09:51) Post-harvest applications(14:44) Future research focus(16:52) Closing thoughtsThe Poultry Nutrition Blackbelt Podcast is trusted and supported by innovative companies like:* Kerry- Zinpro- Anitox- Poultry Science Association- BASF
In this week's episode, we discuss the relationship between infectious and chronic disease, and between germ theory and terrain theory of disease. Pathogens are real, and exogenous treatments like antibiotics can kill them. The health of the body is affected by diet, exercise, stress, and the microbiome, all of which can affect how susceptible a person is to getting sick from pathogens. We discuss gastric ulcers, Covid-19, pneumococcal disease, and comorbidities. Also: how do traditional vs modern diets affect the health, dental and otherwise, of people? Why do pre-industrial people not get cavities, or need orthodontia? Why do squirrels fed by humans develop similarly malformed skulls as babies fed modern diets? Finally: do we have a responsibility to point out the carnage that will result as the Trump administration goes after decades of entrenched interests?*****Our sponsors:Caraway: Non-toxic, beautiful, light ceramic cookware. Save $150 on a cookware set over buying individual pieces, and get 10% off your order at http://carawayhome.com/DarkHorse.Manukora: the most flavorful, delicious, and nutritious honey you'll ever have. Get $25 off your starter kit at http://www.Manukora.com/DarkHorseARMRA Colostrum is an ancient bioactive whole food that can strengthen your immune system. Go to http://www.tryarmra.com/DARKHORSE to get 15% off your first order.Mentioned in this episode:*****Join us on Locals! Get access to our Discord server, exclusive live streams, live chats for all streams, and early access to many podcasts: https://darkhorse.locals.comHeather's newsletter, Natural Selections (subscribe to get free weekly essays in your inbox): https://naturalselections.substack.comOur book, A Hunter-Gatherer's Guide to the 21st Century, is available everywhere books are sold, including from Amazon: https://amzn.to/3AGANGg (commission earned)Check out our store! Epic tabby, digital book burning, saddle up the dire wolves, and more: https://darkhorsestore.org*****Mentioned in this episode:RFK Jr on chronic and infectious disease: https://x.com/ChildrensHD/status/1885018213701800387RFK Jr on The Real Anthony Fauci: https://amzn.to/40INnxF (commission earned)Marshall et al 1985. Attempt to fulfil Koch's postulates for pyloric Campylobacter. Med J Aust. 142:436–9:https://onlinelibrary.wiley.com/doi/abs/10.5694/j.1326-5377.1985.tb113443.xEvolutionary Lens Livestream #88 – w discussion of Covid x comorbidities: https://www.youtube.com/watch?v=KSWu6DUFFt4&t=337sHanada et al 2021. Multiple comorbidities increase the risk of death from invasive pneumococcal disease under the age of 65 years. Journal of Infection and Chemotherapy, 27(9): 1311-1318: https://www.sciencedirect.com/science/article/abs/pii/S1341321X21001252Nutrition and Physical Degeneration, by Weston Price (1939): https://amzn.to/4jXciXl (commission earned)Chandler et al 2025. Morphological change in an isolated population of red squirrels (Sciurus vulgaris) in Britain. Royal Society Open Science, 12(1): 240555.https://royalsocietypublishing.org/doi/10.1098/rsos.240555Support the show
With the monitoring of foodborne pathogens attracting even more focused efforts, today's MeatingPod guest offers insights on methodologies that a recent study of Campylobacter showed that the pathogen could still be detected in poultry sold on store shelves. Dr. Agneta Dziegiel is a researcher at the Quadrum Institute in Norwich, England, and was part of a research team that used a variety of sampling techniques to uncover how Campylobacter isolates can slip through food safety monitoring practices and threaten public health.
Es una infección que se presenta en el intestino delgado por la bacteria llamada Campylobacter jejuni. Esto es un tipo de intoxicación alimentaria bacteriana.
Dr. Don and Professor Ben talk about the risks of blowing air over raw chicken. Dr. Don - not risky
This week, LaLa shares an update on Gio's recent ER visit and the surprising diagnosis of Campylobacter. The girls dive into parenting struggles as LaLa opens up about raising her strong-willed 2.5-year-old, Giulina, and the unique differences between parenting her and Gio. Plus, they sit down with Nanit CEO, Anushka Salinas, for expert insights in their ongoing baby segment. Don't forget to enter their Baby Giveaway on social media for a chance to win! Use code shawnaandlala20 for 20% off your purchase on Nanit. (Offer cannot be applied to previous purchases or combined. Offer valid only on full-priced items. Offer does not include bundle builder and is not valid on gift cards. Some partner brand products are excluded.) #shawnaandlala #nanit #anushkasalinas #babygiveaway #tech #babymusthaves
La diarrea es un problema común que puede ser causado por diversas razones. Aquí están algunas de las causas más comunes y sus tratamientos:Causas de la diarrea:Infecciones virales: Los virus como el norovirus, rotavirus o adenovirus pueden causar diarrea.Infecciones bacterianas: Bacterias como Escherichia coli, Salmonella, Shigella y Campylobacter pueden ser responsables.Parásitos: Parásitos como Giardia lamblia y Cryptosporidium pueden provocar diarrea.Intolerancias alimentarias: La intolerancia a la lactosa o al gluten puede causar diarrea.Medicamentos: Antibióticos, laxantes y ciertos medicamentos para el corazón pueden inducir diarrea.Enfermedades digestivas: Enfermedades inflamatorias del intestino, como la enfermedad de Crohn y la colitis ulcerosa, pueden ser responsables.Estrés y ansiedad: El estrés emocional puede desencadenar episodios de diarrea.Alimentos contaminados: Consumo de alimentos en mal estado o contaminados con bacterias o toxinas.Tratamiento de la diarrea:Rehidratación:Oral: Soluciones de rehidratación oral (SRO) disponibles en farmacias son esenciales para reponer líquidos y electrolitos.Intravenosa: En casos severos, puede ser necesaria la administración de líquidos por vía intravenosa.Dietas blandas:BRAT: Dieta a base de plátano, arroz, compota de manzana y tostadas puede ser útil para asentar el estómago.Evitar alimentos irritantes: Evitar productos lácteos, grasas, alimentos picantes y bebidas alcohólicas o con cafeína.Medicamentos antidiarreicos:Loperamida: Ayuda a reducir la frecuencia de las deposiciones.Subsalicilato de bismuto: Útil para tratar diarrea del viajero y calmar el estómago.Tratamiento de la causa subyacente:Antibióticos: Si la diarrea es causada por una infección bacteriana.Antiparasitarios: Si la causa es una infección por parásitos.Cambio de medicamentos: Consultar al médico si la diarrea es causada por medicamentos.Probióticos:Pueden ayudar a restablecer la flora intestinal y reducir la duración de la diarrea.Evitar deshidratantes:Beber suficiente agua y evitar bebidas que puedan empeorar la deshidratación, como el alcohol y la cafeína.Cuándo buscar ayuda médica:Si la diarrea dura más de 48 horas.Si hay signos de deshidratación severa (sequedad en la boca, orina oscura, mareos).Si hay fiebre alta, sangre en las heces o dolor abdominal severo.En el caso de niños pequeños y personas mayores, buscar ayuda médica si la diarrea es persistente.Es importante recordar que estos tratamientos pueden variar dependiendo de la causa específica de la diarrea y la condición general del paciente. Siempre es recomendable consultar a un profesional de la salud para un diagnóstico y tratamiento adecuados.Conviértete en un seguidor de este podcast: https://www.spreaker.com/podcast/comiendo-con-maria-nutricion--2497272/support.
While many microbes bring benefits, pathogens are the focus when ensuring food safety. This episode dives into practical tips for enjoying chicken, whether you buy chicken or eggs from the store or raise your own chickens for eggs in your backyard.Join food safety expert Dr. Andrea Etter as she shares insights into preventing foodborne illnesses caused by bacteria like Salmonella and Campylobacter. Dr. Etter is an assistant professor specializing in food microbiology and food safety at the University of Vermont. From her vast knowledge, you'll learn how to prepare chicken at home safely and even keep your own backyard chickens.By understanding basic food safety practices, we can protect ourselves and our loved ones while not forgetting the many positive roles of microbes in our lives.Dr. Etter will equip you with strategies for safe chicken handling, from effective cooking techniques to proper backyard coop hygiene.Join us as we explore food safety. I hope this empowers you to make informed choices for safe chicken handling.Topics covered in this episode:Dr. Etter's background and path to food microbiologyFood safety from grocery shopping to meal consumptionCommon pathogens like Salmonella and Campylobacter in chickenSalmonella and Campylobacter risks and prevention strategiesHandling and food safety of raw store-bought chickenMicrobial risks of backyard chickens and tips for safe raising practicesJOYFUL MICROBE SHOW NOTES: https://joyfulmicrobe.com/chicken-safety-andrea-etter/JOYFUL MICROBE TWITTER: https://twitter.com/joyfulmicrobe/JOYFUL MICROBE INSTAGRAM: https://www.instagram.com/justineldees/SUPPORT JOYFUL MICROBE: https://ko-fi.com/joyfulmicrobe/
In this episode, we review the high-yield topic of Campylobacter jejuni from the Microbiology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets --- Send in a voice message: https://podcasters.spotify.com/pod/show/medbulletsstep1/message
Dr. Don and Professor Ben talk about the risks of consuming ice stored under factory package frozen raw ground beef. Dr. Don - not risky
Au mois de juillet, le Pérou a recensé 4 décès et plus de 190 cas d'atteinte par le syndrome de Guillain-Barré, au point de déclarer l'état d'urgence. La situation est depuis suivie avec attention par l'OMS. Si la cause précise de ce syndrome n'est pas toujours connue, elle est souvent liée à certains facteurs déclencheurs donc les infections. Ce qui est susceptible de provoquer le SGB Maladie rare et grave, le syndrome de Guillain-Barré consiste en une inflammation des nerfs périphériques pouvant occasionner une paralysie temporaire ou permanente. Elle survient, dans 2 tiers des cas, après une infection. Ce peut être une infection respiratoire ou gastrointestinale, mais certains virus et bactéries semblent plus ciblés comme le virus de la grippe, le virus Zika, la dengue et la bactérie Campylobacter jauni. Il est supposé que le corps réagisse à l'infection en déclenchant une réaction immunitaire anormale, qui s'attaque aux nerfs périphériques des membres supérieurs et inférieurs. Concrètement, après l'infection initiale, le système immunitaire cible les gaines de myéline qui entourent les nerfs au lieu de s'attaquer aux agents pathogènes. La maladie dite auto-immune provoque des dommages au niveau des muscles et des troubles de la sensibilité comme des picotements ou des fourmillements. L'influence des vaccins Une étude publiée en 2022 s'est intéressée à la survenue du syndrome de Guillain-Barré après une vaccination contre le virus SRAS-CoV-2, communément appelé du nom de la maladie qu'il provoque, le Covid-19. Bien que des cas de SGB ait effectivement été observés après la vaccination, les auteurs mentionnent également que davantage de cas ont été mentionnés des suites d'un Covid-19 sans vaccination. C'est alors au médecin de déterminer l'ampleur du bénéfice/risque, notamment en considérant les antécédents de la personne et sa sensibilité immunitaire. Une autre étude relayée en 2023 par l'Agence Nationale de Sécurité du Médicament a montré que les vaccins à ARNm ne présentaient pas de risque de déclencher un syndrome de Guillain-Barré. En revanche, les vaccins à vecteur adénoviral augmentent le risque d'apparition du syndrome dans les 6 semaines suivant l'administration de la dose. Le SGB après une intervention chirurgicale Les interventions chirurgicales sont une autre cause admise de risque de déclencher un SGB. Il s'agit d'un évènement rare, qui s'explique peut-être par le stress que le corps connait durant la chirurgie. Celle-ci est susceptible de provoquer une réponse immunitaire anormale, donc un SGB, alors diagnostiqué dans les jours ou semaines suivant l'opération. Learn more about your ad choices. Visit megaphone.fm/adchoices
Au mois de juillet, le Pérou a recensé 4 décès et plus de 190 cas d'atteinte par le syndrome de Guillain-Barré, au point de déclarer l'état d'urgence. La situation est depuis suivie avec attention par l'OMS. Si la cause précise de ce syndrome n'est pas toujours connue, elle est souvent liée à certains facteurs déclencheurs donc les infections.Ce qui est susceptible de provoquer le SGBMaladie rare et grave, le syndrome de Guillain-Barré consiste en une inflammation des nerfs périphériques pouvant occasionner une paralysie temporaire ou permanente. Elle survient, dans 2 tiers des cas, après une infection. Ce peut être une infection respiratoire ou gastrointestinale, mais certains virus et bactéries semblent plus ciblés comme le virus de la grippe, le virus Zika, la dengue et la bactérie Campylobacter jauni. Il est supposé que le corps réagisse à l'infection en déclenchant une réaction immunitaire anormale, qui s'attaque aux nerfs périphériques des membres supérieurs et inférieurs.Concrètement, après l'infection initiale, le système immunitaire cible les gaines de myéline qui entourent les nerfs au lieu de s'attaquer aux agents pathogènes. La maladie dite auto-immune provoque des dommages au niveau des muscles et des troubles de la sensibilité comme des picotements ou des fourmillements.L'influence des vaccinsUne étude publiée en 2022 s'est intéressée à la survenue du syndrome de Guillain-Barré après une vaccination contre le virus SRAS-CoV-2, communément appelé du nom de la maladie qu'il provoque, le Covid-19. Bien que des cas de SGB ait effectivement été observés après la vaccination, les auteurs mentionnent également que davantage de cas ont été mentionnés des suites d'un Covid-19 sans vaccination. C'est alors au médecin de déterminer l'ampleur du bénéfice/risque, notamment en considérant les antécédents de la personne et sa sensibilité immunitaire.Une autre étude relayée en 2023 par l'Agence Nationale de Sécurité du Médicament a montré que les vaccins à ARNm ne présentaient pas de risque de déclencher un syndrome de Guillain-Barré. En revanche, les vaccins à vecteur adénoviral augmentent le risque d'apparition du syndrome dans les 6 semaines suivant l'administration de la dose.Le SGB après une intervention chirurgicaleLes interventions chirurgicales sont une autre cause admise de risque de déclencher un SGB. Il s'agit d'un évènement rare, qui s'explique peut-être par le stress que le corps connait durant la chirurgie. Celle-ci est susceptible de provoquer une réponse immunitaire anormale, donc un SGB, alors diagnostiqué dans les jours ou semaines suivant l'opération. Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.
Campylobacter and the BBQ season go hand-in-hand. Each year 5800 cases of the foodborne illness are reported in New Zealand, and almost 1000 people will end up in hospital. In this week's podcast, host Carol Stiles is in the kitchen with the head of NZ Food Safety, Vincent Arbuckle who has some simple tips that will keep you and your guests safe this summer. Hosted on Acast. See acast.com/privacy for more information.
Dr. Don and Professor Ben talk about the risks of the USDA recommended cold water turkey thawing method. Dr. Don - not risky
Dr. Don and Professor Ben talk about the risks shopping in the produce section of a store where someone has brought their pet turtle. Dr. Don - risky ☣️ Professor Ben - not risky
What an absolute mess our waters are in. Drinking water regulator Taumata Arowai has put 27 councils on notice to have a plan and funds locked in to fix their drinking water supplies by June of next year. I was actually surprised that so many councils still have issues with their drinking water. Still haven't put in barriers to protect against the cryptosporidium and guardia that can be spread through drinking water supplies, especially given the Campylobacter outbreak in Hastings in August 2016. More than 5000 people were violently ill and the outbreak has been linked to three deaths. So I would have thought that any Council that didn't have treatment in place would have made it a priority to get those barriers put in to prevent their people getting contaminated, getting sick from contaminated drinking water. But no, here we are in 2023, with a cryptosporidium outbreak in Queenstown. Since 2016, we've also had issues with drinking water in east Otago, although that was lead contamination not Protozoa which is the all-encompassing name for the bugs. We've had issues with wastewater run off again in Queenstown. The Council sought permission in 2018 for untreated wastewater, sewage basically, to continue being pumped into the lakes and rivers in Queenstown for the next 35 years. Those beautiful pristine lakes getting pumped full of literal crap. We've got issues in Wellington with wastewater going into the harbour. We've got people in Inner city Auckland being issued drinking water and dealing with sewage bubble ups as engineers try to fix a huge sinkhole in Parnell. There are other examples. There is an absolute urgent need to overhaul and upgrade our three water systems, hence what the Labour Government was trying to do with its Three Waters. But they made an absolute hash of it. So Taumata Arowai has put the councils yet to do the necessary work on notice. Queenstown Mayor Glyn Lewers was on Early Edition this morning. He believes water regulator Taumata Arowai is undermining the very industry they're trying to regulate, and the costs will be passed on to ratepayers. The bit that concerns me is I think the regulators are probably undermining the industry they're trying to regulate, that's the fear I've got. So what's going to happen is they're all competing against each other now against the scarce resource, and that's the industry resource and also the supply resource. So you can just imagine the consultancy rates and the supply rates are only going go one way and it's up. It just gets passed straight on the ratepayers, so ratepayers can expect a fair increase in rates, I'd suggest. Yeah again, I don't quite follow the reasoning. So Queenstown knows they haven't had a barrier to protect the drinking water for years. They know they've got problems with their wastewater pumping out into the lakes. The other 26 councils presumably know that they have no treatment in place to protect their drinking water. The Campylobacter outbreak in Hastings was in August 2016, so here we are seven years later and now all of a sudden saying, oh man, we're going to have to really scramble for resource. Well, if you'd pulled your finger out and got the job done and prioritised it, you wouldn't all be competing at the same time, would you? So it's no good pointing the didgeridoo at Taumata Arowai and saying, oh, now you're forced us into this position and now we're going to have to compete for a scarce resource. There wouldn't be a scarce resource if you had used the seven intervening years between when there'd been a Campylobacter outbreak that made so many people so very, very ill to do something. Seven years later what have you been doing? You leave it till you run the risk of prosecution. You find yourself competing with the same consultants, the same equipment. The price goes up. That's on you. See omnystudio.com/listener for privacy information.
Cocktails for Pets Taryn Nahm wants you to kick back a few cocktails with your pet. She says you can bond with your pet while you relax with a beverage. Taryn created pet cocktails that look just like the human adult versions, except without alcohol. Listen Now Fear Free Tips You Can Use Do you have trouble getting your pet to the vet? You're not alone. Certified Trainer Mikkel Becker has some great ideas for making a vet visits easy and enjoyable. Check out our Fear Free Expert Series. Listen Now Antibiotic Resistant Virus Outbreak There has been a Campylobacter outbreak associated with puppies sold at Petland stores and it's the humans that have handled these puppies that are getting sick. So far, more than 55 people in 12 states have now been diagnosed in this outbreak, which is so serious that at least a fourth of the patients have been hospitalized. Listen Now Millenials Choosing Pets Instead Millennials, or Generation Y, are those born between 1982 and 2004 and they are quickly changing the world of pets. According to the American Pet Products Association, Millennials are now the largest segment of pet owners. They found Millennials invest more time in their pets, evaluating their needs more thoroughly and spending more money. Listen Now If Your Pet Is Unwell - You Might Be Unwell Too New research shows that if your pet is unwell, it can make you unwell, leading to depression, anxiety and a poorer quality of life. It's the same problem that was previously found in the human world. Listen Now Read more about this week's show.
Guests: Andy Vance, PSA; Dr. John Halley, J. Halley Poultry Consulting; Addison Elstner, Texas A&M University; Dr. Chasity Pender, DSM Nutritional Products; Dr. Valentina Caputi, USDA-ARS Poultry Production and Product Safety Research Unit; and Dimitri Malheiros and Dr. Ken Anderson, North Carolina State UniversityToday's episode was filmed at the 2023 Poultry Science Association Annual Meeting in Philadelphia, PA. Balchem's technical team chose abstracts of interest from the meeting and those researchers are our guests today. We kick off the show with Andy Vance, Executive Director of the Poultry Science Association. Andy speaks to the growth of the conference, the presentations and attendance and reinforces that the Poultry Science Association exists to advance science in the poultry industry. (01:20)Our second guest is Dr. John Halley with J. Halley Poultry Consulting. John conducted an industry survey about how companies handle data. Are companies digitizing data or just staying with what they've been doing? John's presentation covered how data flows through poultry companies today, as well as where we may be going in the future. (05:56)John's abstract was titled: “Current Data Insights and Practices for a Poultry Nutritionist”Next on the guest roster is Addison Elstner from Texas A&M University. Addison's research objective was to use a different basal diet than traditional corn and soy to stress birds with high inclusions of other cereal grains. This effort was to create a preliminary model of different cereal diets and their impact on intestinal health, performance and animal welfare. This preliminary work builds a foundation for the addition of feed additives and enzymes to those nontraditional diets in the future. (12:04)Addison's abstract was titled: “Phase ingredients change in the diet formulation as a possible model to test feed additive efficacy in broiler chickens” Our fourth guest is Dr. Chasity Pender from DSM Nutritional Products. Her abstract presented data compiled over the past year for vitamin A recovery levels. The DSM internal laboratory had samples of broiler, broiler breeder vitamin premixes, and broiler and broiler breeder feeds. With those samples, they measured vitamin A recovery levels and evaluated the variation in the different feedstuffs. (15:09)Chastity's abstract was titled: “Evaluation of Vitamin A Recoveries in Broiler and Broiler Breeder Premixes and Finished Feeds”The next guest in our lineup is Dr. Valentina Caputi with the USDA-ARS Poultry Production and Product Safety Research Unit in Fayetteville, Arkansas.The main objective of her research is to look for alternatives to antibiotics to fight the carriage of foodborne pathogens in the poultry industry. Dr. Caputi's specific expertise is the study of the enteric nervous system, which is the nervous system that is intrinsic on the gut wall and is distributed throughout the overall gastrointestinal tract. Her abstract evaluated how heat stress during the pre-harvest stage of poultry production affects the enteric nervous system, the intestinal microbiota, and overall gut health and how this can predispose the animal to be susceptible to colonization by a food pathogen, such as salmonella or campylobacter. (21:34)Valentina's abstract was titled: “Heat stress induces regional-dependent modulation of aquaporin 4 expression in the enteric nervous system of broiler chickens”Lastly, we are joined by Dimitri Malheiros and Dr. Ken Anderson, from North Carolina State University. Dimitri's research assessed cage densities during the pullet rearing phase. While other previous studies focused on increased stocking densities, Dimitri and Dr. Anderson wanted to focus on lower stocking densities to evaluate if pullet welfare would be improved in less dense cages. (32:42)Dimitri's abstract was titled: “Influence of cage rearing density on pullet growth parameters and fearfulness.”Be sure to subscribe so you don't miss the additional highlights from the 2023 Poultry Science Association Annual Meeting in future podcast episodes. If you want one of our new Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we'll get a shirt in the mail to you.
Dr. Mark Pimentel discusses New Research Findings on SIBO and IBS at the Functional Medicine Discussion Group meeting on May 25, 2023 with moderator Dr. Ben Weitz. [If you enjoy this podcast, please give us a rating and review on Apple Podcasts, so more people will find The Rational Wellness Podcast. Also check out the video version on my WeitzChiro YouTube page.] Podcast Highlights 4:24 Dr. Pimentel started a fellowship at Cedars in 1996 on motility and his colleagues questioned why he would want to get involved with treating IBS patients, who are psychologically altered? Patients with IBS seemed like regular folks who were struggling and it is too easy to attribute medical conditions that are not well understood to psychological causes. He reflected on when heart disease was thought to be primarily due to stress and in the early 70s if you had a heart attack, you were told that you needed to quit your job. But it turned out that what caused their heart attack was more due to the steakhouse with the cholesterol and the alcohol and the smoking and your genetics and all the other things we learned about cardiovascular disease. One of his colleagues in 1996 told him that "IBS is a disease of hysterical women." 5:41 Anti-diarrheals. Even in the last three years, the AGA guidelines say that anti-diarrheals like Imodium should be first-line therapy for irritable bowel syndrome because they're cheap. This is not a good reason to recommend a medication, rather than trying to figure out the cause of IBS and then treating that. This is because the research that Dr. Pimentel has conducted and published for the last 26 years that demonstrates that SIBO is the main cause of IBS has still not been fully accepted by the GI community. 6:36 Food poisoning is the cause of about 60% of cases of IBS-D and there is now enough research data to prove this. The bacteria that cause food poisoning, whether it be E. coli or Campylobacter or Shigella or Salmonella secrete an endotoxin--Cytolethal Distending Toxin (CDT) and specifically the B version of CTD--CDTB--that leads to SIBO/IBS. The immune system reacts to the CDTB and those anti-CDTB antibodies end up cross reacting with a structural protein in the intestinal wall called Vinculin. Thus the immune system is attacking the body, an auto-immune reaction. This leads to damage of the nerves that control the intestinal cleansing waves, which leads to a buildup of the bacteria in the small intestine (SIBO). These small intestinal cleansing waves are peristaltic waves that are occur when you haven't eaten for more than 3 or 4 hours, which help to clear out excess bacteria. These cleansing waves are caused by the deep muscular plexus-interstitial cells of Cajal. Dr. Pimentel has developed a second generation test that measures antibodies to CDTB and to vinculin via blood testing that is extremely accurate, the IBS Smart test from Gemelli Biotech. 25:37 Methane SIBO (IMO) does not appear to be caused by food poisoning. By paralyzing the gut in the case of hydrogen and hydrogen sulfide SIBO, this can lead to diarrhea. In the case of methane, this causes the gut to hypercontract and this overcontraction of the gut muscles leads to constipation. 29:33 In a study published in 2020 Dr. Pimentel's group showed that a lactulose breath test--not a glucose breath test--and using the 90 minute cutoff of more than 20 parts per million increase in hydrogen it correlated well with the bacteria in the gut seen in culture and the hydrogen-producing enzyme machinery in the small intestine was elevated. This shows that the hydrogen is being produced in the small intestine and not in the colon. (Leite G, Morales W, Weitsman S, Celly S, Parodi G, Mathur R, Barlow GM, Sedighi R, Millan MJV, Rezaie A, Pimentel M. The duodenal microbiome is altered in small intestinal bacterial overgrowth. PLoS One. 2020 Jul 9;15(7):e0234906.)
Dr. Don and Professor Ben talk about the risks from licking a plate that had raw chicken juice on it and was only cleaned with Norwex. Dr. Don - risky ☣️ Professor Ben - not risky
Dr. Bruce Stewart-Brown of Perdue Farms outlines the goals of a new partnership between Perdue, Cornell University and the University of Illinois that aims to study Campylobacter and Salmonella contamination at poultry processing plants. The collaboration is an extension of Perdue's existing programs that use data collected from farm to processing facility to advance statistical analysis efforts, develop models and create concrete methods to reduce pathogen exposure on the processing plant level. He notes that these collaborations ultimately can help poultry companies improve overall food safety.
“What I did not expect to see from farmed monkeys being bought and transported into the US, were monkeys who were coming in with things like Ebola like viruses, malaria, tuberculosis, simian retrovirus, herpes viruses, salmonella, Yersinia, Campylobacter, unnamed deadly diarrheal diseases. They were coming in with Tier 1 Select agents. I mean, we're talking pathogens so deadly that the government has identified them as potential bioterrorism threats.” – Lisa Jones-Engel In 2022, 1000 long-tailed macaques were stolen from the wild in Cambodia. They were then illegally imported to Charles River Laboratories in Texas. Illegal because they were wild caught and not born in captivity, which is the law for importing primates into the US for research and experimentation, they are required to be captive bred. These macaques are now caught in the middle of an ongoing federal investigation into primate importers. Charles River wants to send them back to Cambodia, which means that from there they'll go to labs in other countries. PETA is fighting hard to get them sent to Born Free's Primate Sanctuary in Texas. One of the leaders in this battle is Dr. Lisa Jones-Engel. A couple of weeks ago, Lisa came on the show for a live episode to talk about the fate of these monkeys and what could be the beginning of the end of importing primates for experimentation. Because we did this interview as a webinar and Lisa was in a remote part of Alaska, the sound isn't the best, but this is a super important episode. Lisa spent many years working in biomedical laboratories with primates. She knows everything that goes on on the inside of these facilities and knows first-hand that no one in there is looking out for these animals. In 2019, when she couldn't take it anymore, Lisa left the biomedical world and joined forces with PETA. She's PETA's Senior Science Advisor, and not only leading the fight to save these 1000 monkeys, but also to end all imports and then, to end the use of primates in animal research and experimentation period. I think that she can do it. Links: PETA Petition https://support.peta.org/page/50306/action/1?locale=en-US PETA https://www.peta.org/media/news-releases/trafficked-monkeys-still-stateside-peta-pledges-1-million-for-sanctuary-placement/ PETA: https://headlines.peta.org/primatologist-perspective-monkey-experiments/ Guardian article: https://www.theguardian.com/world/2022/may/31/primates-monkeys-scientific-experiments-peta-stop-testing
This episode discusses four MMWR reports. The first report highlights chronic pain among U.S. adults. The second report looks at mpox cases in the United States. The third report examines mpox-associated deaths in the United States. And the last report describes an outbreak of Campylobacter in Montana.
In this episode, Manpreet Singh, department head and professor of the Food Science & Technology department at the College of Agricultural & Environmental Sciences at the University of Georgia discusses research on evaluating best practices for Campylobacter and Salmonella reduction in poultry processing plants. Dr. Singh, a veteran in food safety, also will outline the work he and his students are conducting in an effort to limit pathogen risks during poultry processing operations.
Campy Show Notes: Cause of Death has a website! Come visit me at www.causeofdeath100secs.net. I also have an email address for the show at Jackie@causeofdeath100secs.net. Feel free to interact with me in either place! I'm going to be doing a special 100 Seconds to Midnight episode in Season 7. I'd like those of you who had experiences growing up during the Cold War to talk about those experiences. If you'd like to be a guest on the show, I can arrange that. If you'd rather just write your stories and send them in, that's fine, too. I can read them. These stories are important, and they need to be heard. Please participate if you can. You can reach me on the website at www.causeofdeath100secs.net or you can email me at Jackie@causeofdeath100secs.net. My Link Tree can be found at: https://linktr.ee/CauseofDeathpod Etiology and Pathology: https://academic.oup.com/cid/article/32/8/1201/479374 https://www.cdc.gov/campylobacter/technical.html https://www.who.int/news-room/fact-sheets/detail/campylobacter https://www.ncbi.nlm.nih.gov/books/NBK537033/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627687/pdf/10081669.pdf https://emedicine.medscape.com/article/213720-overview https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/campylobacter-jejuni https://www.nature.com/articles/s41579-018-0037-9 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/campylobacter-jejuni.html https://www.frontiersin.org/articles/10.3389/fmicb.2011.00200/full https://www.researchgate.net/publication/286562077_The_history_of_Campylobacter_Taxonomy_and_nomenclature https://www.sciencedirect.com/science/article/pii/S1198743X14633528 Darkcast Network – Promo by Yours Truly Podcast Promos: Ye Olde Crime Full Circle – the Podcast Music: There is No Sequel by Philip Ayers You can reach me on: Instagram and FB: @CauseofDeath Twitter: @CauseofDeath10 Please don't forget to rate and review on any of the platforms found here: www.causeofdeath100secs.net You can support Cause of Death here: Subscribe on Apple Subscriptions Patreon: https://www.Patreon.com/JackieMoranty Ko-Fi: https://www.ko-fi.com/causeofdeathluckycharmsunplugg Merch can be found at: https://www.teepublic.com/user/causeofdeathluckycharmsunplugged Please share this podcast with everyone you know. Cause of Death is a proud member of the Darkcast Network. Find us at @darkcastnetwork on Twitter and @DarkcastNetwork on Facebook. Cause of Death can be found on all major podcast platforms.
3.19 Campylobacter Jejuni Microbiology review for the USMLE Step 1 exam Campylobacter jejuni is a gram-negative, comma-shaped bacteria that causes diarrheal illness It is the most common cause of bacterial diarrhea in the US It can be distinguished from other gram-negative, comma-shaped bacteria by its desired culture temperature of 42C/107F It is mostly acquired through consumption of raw milk, undercooked poultry, and contaminated water 90% of cases in the US occur during the summer months, likely due to increased grilling of poultry Symptoms include high fever, rigors, dizziness, body aches, diarrhea (more than 10 stools a day), abdominal cramping, and nausea Complications include Guillain-Barré syndrome (GBS) and reactive arthritis Diagnosis is typically made through a stool culture Treatment typically includes supportive care and replenishing fluids and electrolytes, with antibiotics (macrolides) used for more severe cases.
3.04 Gram Negative Bacteria Microbiology review for the USMLE Step 1 Exam. Gram negative bacteria are characterized by a thin cell wall surrounded by a lipid outer membrane They do not retain the violet gram stain and appear pink after staining Gram negative bacteria can be classified by shape: cocci, coccobacilli, bacilli, and spirals Gram negative cocci include Neisseria species, which can be further categorized as maltose fermenters or non maltose fermenters Gram negative coccobacilli include: Bordetella pertussis, Haemophilus influenzae, Pasteurella, Francisella tularensis, Brucella, and Acinetobacter Gram negative bacilli can be divided into lactose fermenting and non lactose fermenting categories Lactose fermenting gram negative bacilli include: Escherichia coli, Klebsiella, Enterobacter, Citrobacter, and Serratia Non lactose fermenting gram negative bacilli can be further divided into oxidase positive and oxidase negative Oxidase positive non lactose fermenting gram negative bacilli include Pseudomonas Oxidase negative non lactose fermenting gram negative bacilli include Shigella, Yersinia, and Salmonella Gram negative spirals can be divided into oxidase positive and oxidase negative categories Oxidase positive gram negative spirals include Vibrio species, Helicobacter pylori, and Campylobacter jejuni Oxidase negative gram negative spirals include Borrelia burgdorferi (cause of lyme disease) and Treponema pallidum (cause of syphilis)
When you're facing floods, you'll want to take a few precautions. You don't want to end up contaminated by floodwater and you don't want to ruin your carpets. There are a few things you can do to prepare, including removing items that can't be cleaned and finding products that can help you clean up the mess.Precautions to takeIf you have been affected by a flood, you will want to know the precautions to take when cleaning up. This may include removing contaminated materials, avoiding certain areas, and practicing safe cleaning practices. You also need to be aware of potential chemical hazards.A flooded area may contain fecal material from overflowing sewage systems. These can cause infections. It is important to disinfect all of your surfaces after a flood. The CDC recommends using a household bleach solution to do so.When returning to your home after a flood, you will need to throw away any contaminated insulation, food, or water. Some items, such as books, can be placed in bags for safe storage.Make sure that you wear protective clothing when working on a flood cleanup. Use rubber or plastic boots, gloves, and a hat. Avoid wading in standing water. Wear long sleeves and pants.Keep your children away from contaminated areas. They should not play in floodwater, and they should not touch anything that has come into contact with the water.Products that can help remove waterThere are many products available to help remove water during flood cleaning. A wet/dry shop vac is particularly useful for removing excess water from soaked items. You can also use a sprayer to apply a 10% bleach solution to a flooded surface.When cleaning a flooded area, you want to take the time to do it right. This means disinfecting, removing standing water, and ensuring that any airborne contaminants are removed.The right tools, like a wet/dry shop vac, can speed up the cleanup process. While you're at it, you might want to check your power lines for damage. If you find any, call your utility company and have them repaired.One product that should not be overlooked is a good dehumidifier. Not only will it aid in drying your home, but it will also remove odors. However, you'll need to be careful about using this in small areas, because it can draw moisture from the air.Carpets that can't be cleanedWhen it comes to water damage, carpets are the first to suffer. Even a small amount of water soaking into the fabric of your carpet will cause it to shrink and possibly buckle.The best way to avoid this is to dry out your carpet as soon as possible. You can use dehumidifiers, fans, and wet/dry vacuums to help speed up the drying process.Depending on the source of your flood, the water may be clean or contaminated. If the latter, the most important thing to do is to get the source repaired. Otherwise, you'll have to worry about a variety of health hazards.Besides repairing the source, you should also remove the water as soon as possible. This will prevent mold from growing on the fabric.To do this, you'll want to roll up your carpet to allow it to dry out beneath. You can also try opening windows to encourage air circulation.Contamination of items in floodwaterFloods are an inevitable part of life, but they can also expose you to dangerous chemicals and bacteria. This is because floodwaters can be contaminated with sewage, animal waste, and industrial waste.Several studies have examined the chemical and pathogen levels of floodwater. Some found increased levels of illness after flooding. However, these results are likely due to seasonal variation.Most surface water samples contained high levels of arsenic, copper, manganese, lead, and zinc. Additionally, samples had higher adenovirus and total coliform counts. Please use Service Restoration to improve your flood damage restoration in Arkansas.If floodwater enters your home, you should discard all foods in plastic, cork, and metal cans. You should also throw away any items that absorb or soak up floodwater.When you are cleaning after a flood, it is important to wear protective clothing. It is also important to clean your hands thoroughly with soap and running water. Wear gloves when you handle contaminated items.During a flood, you should avoid contact with animals. Floodwater can carry a variety of harmful bacteria, including the disease-causing organisms Campylobacter, Salmonella, and E. coli. These bacteria can cause nausea, vomiting, gas, diarrhea, and stomach pain.Service Restoration Inc. is a professional Flood cleaning provider in Little Rock. The company provides emergency services to the residents of Little Rock and surrounding areas. Our experienced technicians are available 24/7 and provide free estimates to arrive at the most cost-effective solution for your Flood cleanup problem.Contact us:Service Restoration7821 Doyle Springs Rd Suite F Little Rock, AR 72209(501) 381-5440
This Summer people are being urged to be very careful when it comes to cooking chicken. In fact so serious is the ministry of Primary Industries about foodborne illnesses from chicken have launched a campaign.
In Ep. 85, we'll learn how Dr. Sukumaran and his students at Mississippi State's Department of Poultry Science focus on developing successful strategies aimed at reducing bacterial pathogens in poultry meat products. Sukumaran's current focus also includes helping poultry processors through workshops and training sessions that promote best practices in their operations. He notes that processors are doing more to prevent contamination from such pathogens as Salmonella, Campylobacter and E. coli than even a decade ago. He also suggests that the industry establish constant monitoring programs and upgrades in order to produce the safest food products possible for consumers.
Over the break, host of It's Time For Ewe, Fiona Macarthur has been busy going through your feedback.A popular area of feedback was Campylobacter in sheep and so to find out more about this zoonotic disease, Fiona speaks with Dr Joan Lloyd in this episode. Joan completed her veterinary training at the Veterinary College of Western Medicine at the University of Saskatchewan, Canada in 1986.She also has post graduate training in immunology and veterinary pathology at the University of Sydney, Since completing her training she has worked extensively in research roles for the NSW Department of Primary Industries within the pharmaceuticals and livestock industries.
In this episode we talk to Professor Mark Pallen, who discusses the highlights from his long career as a medical microbiologist turned bioinformatician. His bioinformatics journey began in 1977, the year Fred Sanger invented DNA sequencing-as-we know-it, when Mark was tasked with assembling some amino acid sequences under exam conditions. Mark explains how little was know about sequences at the time. Luckily he managed to gain a grasp of molecular biology and joined a group in the late 1908s at Barts Hospital in London, where he met Brendan Wren. Mark's first eureka moment followed shortly afterwards, when he analysed sequences encoding the key enzyme urease from Helicobacter pylori. He also got very excited when he analysed genes from a clostridial butanol fermentation pathway, which he explains, played a central role in the formation of the state of Israel. His next big break came when he got the chance to do a PhD under Gordon Dougan. During this time, Mark not only improved his lab and bioinformatics skills, but captained a winning team in University Challenge and introduced the medical profession to the Internet. He recalls with excitement the moment when he first heard the news that a bacterial genome had been sequenced. Shortly afterwards he recruited an 18-year old gap year student, Nick Loman, to come and work with him analysing the very first Campylobacter jejuni genome. We close this episode just as the new millennium begins, with much more excitement to follow in the next episode. Relevant links: Butanol - https://academic.oup.com/femsle/article/124/1/61/486499 Tree-like thinking for genes, languages and gospel manuscripts - https://www.youtube.com/watch?v=8Ykj5wQs7vU Further references -
La infección por Campylobacter es una enfermedad común transmitida por los alimentos. En Clínica Abierta, el Dr. Elmo Rodríguez, doctor en medicina, ofrece sabios consejos de salud, así como efectivos remedios basados en la medicina natural. Su co-animadora, Lorraine Vázquez, mantiene el ameno curso del programa con sus interesantes preguntas y comentarios.
Dr. Don and Professor Ben talk about the risks from getting kissed by your dog. Dr. Don - not risky
Dr. Don and Professor Ben talk about the risks from getting kissed by your dog.Dr. Don - not risky
If you own a dog, you know what goes into dealing with its poop. Not becomingly, you know a stinky pile of dog poop immediately needs picking up before it becomes an eyesore for neighbors.In the United States, there are more than 89 million dogs[1] and an average dog deposits ¾ pounds of poop every day; that makes up nearly 66 million pounds of pet waste each day!If left unattended, that is a dangerously large pile of dog poop!Dangers of Dog Poop to the EnvironmentIn 1991, the Environmental Protection Agency, or EPA, placed dog poop in the category of “dangerous environmental pollutant,” where it shares its spot with toxic chemicals and pesticides.While it may be a shock to some, an estimated 40% of dog owners do not pick up after their pet. This waste accumulates over time and gets washed away during rainstorms, polluting the waterways! To put this into perspective, if 100 dogs go to the bathroom and their waste is not picked up over the course of 2 to 3 days, enough bacteria would be generated to close bodies of waters, such as bays, within a 20-mile radius.[2] WOW!Which Bacteria and Parasites May Be Contracted by Humans?Apart from being unsightly, dog poop carries numerous harmful bacteria which pose severe risks to human health. So, if you ask yourself, “Is dog poop dangerous?” it sure is!Dog waste is a source of many fatal disease-causing bacteria and parasites. Only one gram of doggie waste contains about 23 million fecal bacteria. The Centers for Disease Control reports that these bacteria can be transmitted to humans, especially small children.Your pets feces may include the likes of:SalmonellaE. coliGiardiaParvo VirusTapewormsRoundwormsCampylobacteriosisHookwormsEchinococcusCoronaIs Dog Poop Dangerous?If infected with any of the above-stated elements, symptoms may range from rashes to fever, diarrhea, liver damage, vomiting, or nervous system breakdown. CDC data shows that 14% of Americans are infected by roundworms, and this is alarming!Campylobacter is another danger of dog poop that can cause gastrointestinal issues in the adults and life-threatening conditions in infants and adults with weak immunity.Pesky parasites like Giardia attack the digestive system, and hookworm larvae cause skin infections.What's the Remedy?A proactive approach of picking up immediately after your pet can help in averting the dangers of dog poop. It should be removed from your lawns every 1-7 days depending on the number of dogs in a household. Larger pooches need frequent cleanups, as their waste is usually larger and more abundant.If you are too busy to scoop the poop on your own or you don't want to deal with your pet's waste, call the experts at POOP 911. Our professionals clean up the pet waste as often as you would like and haul it away from your property. You won't even know they are there!
This week on the Head Shepherd podcast, we're joined by Steve Kelly, Commercial Identification Manager of Allflex, and Kim Kelly, Veterinary Technical Advisor of MSD Animal Health.Allflex has been the sponsor of our podcast since its inception and it is always great to catch up with the team to hear what they're up to.Recently, Allflex was acquired by MSD Animal Health. Steve and Kim describe the companies coming together as "A match made in Heaven”, with the number of synergies between the two companies being beneficial not only to the business but more importantly to farmers. Using the EID technology to help manage animal health and performance at an individual level being just one simple example.Kim was a practicing vet for many years, and has been working as a Technical Advisor for MSD Animal Health for the past 12 years. Her role includes training the internal sales team, veterinary clinics and farm stores and the farming community in New Zealand about the uses and benefits of the company's products and how they can get the most out of their animal health investment.In this podcast, we focus on Campylobacter, an abortion causing bacteria in sheep.Abortion storms in sheep can cause devastating effects yet it is estimated that only 60% of the maiden ewes in NZ get a Campylobacter vaccine, despite approximately 88% of NZ farms having Campylobacter present on their property.Kim takes us through the wide-spread implications of Campylobacter and how abortions storms are really just the tip of the iceberg as Campylobacter can also cause early embryonic loss, stillbirths or the births of weak lambs that die soon after birth.Mark makes a great point in that we put all of our efforts into breeding more lambs, why would we risk all of that, when prevention, in the form of Campyvax4®, is so cheap.Knowing more about how Campylobacter works gives you a greater understanding of why and when you should vaccinate your animals to the greatest benefit to your sheep and your business.If you would like to know more about any of the products mentioned in this podcast, you can visit theMSD Animal Health website below:www.msd-animal-health.co.nzFor Australian listeners you can visit the company's Australian website below which includes the risk calculator mentioned in the podcast or contact the Australian team on 1800 226 511https://www.coopersanimalhealth.com.au/products/OvilisCampyvaxWe will have a Jo Holter from MSD on The Hub for a live Q&A on the 25th of March AT 12.30 NZT, if you have any more questions about abortive diseases or any MSD products.If you are in New Zealand and would like to get in touch with Kim, or another Technical Advisor at MSD Animal Health, phone 0800 800 543 with your enquiry.Check out The Hubthehub.nextgenagri.comOur community where our members have the opportunity to keep up to date with everything we are working on.Thanks to our SponsorsAllflex Livestock Intelligence is the leader in the design, development, manufacturing, and delivery of animal monitoring, identification, and traceability solutions. Their data-driven solutions are used by farmers to manage animals. By putting intelligent, actionable information into farmers' hands, their solutions empower them to act in a timely manner for optimal outcomes.A big thank you to our sponsors, Allflex Livestock Intelligence and MSD Animal Health Intelligencewww.allflex.global/nz/
Ready to think twice about the filtration used to treat your water for consumption? Ready or not, our hosts are exploring the gut microbe, Campylobacter jejuni. This gram-negative bacterium is about 0.2um – 0.5um in size. Small, but mighty enough to warrant the use of a 0.05um filter if you want to catch this bug and potentially avoid some stomach souring symptoms. More about Campylobacter jejuni: What is Campylobacter infection? Safewater.org | Campylobacter Fact Sheet Stay tuned for more episodes, posting on the first Thursday of each month. Subscribe to our show wherever you get your podcasts and find more info at weebeastiespodcast.com The Wee Beasties podcast is a production of Nephros, Inc., a company committed to improving the human relationship with water through leading, accessible technology. *** Campylobacter jejuni, Campylobacter, biosurveillance, microorganisms, biotechnology, PremisePlumbing, AntonVanLeeuwenhoek, WeeBeastiesPodcast, season1, origins, CDC, pathogens, OpportunisticWaterbornePathogen *** SHOW TRANSCRIPT: Christian: I am back with Dr. Kimothy Smith. Kimothy, welcome back! Kimothy: Thanks, Christian. Christian: All right…how are we doing today Kimothy? Kimothy: Doing well, Christian. Just recovering. Christian: Recovering from what? Kimothy: All of the candy corn I had to pick up in my front yard this weekend. The local monsters and ghouls decided it was imperative that my lawn be seeded with candy corn so they could apparently revive a Children of the Corn montage for Halloween. Of course, nothing was going to grow except the number of birds and bugs on my lawn, so I found myself bent over cleaning that crap up all day on Sunday. Sigh. Christian: Well, hey, out of the Steven King flicks to choose from that was probably the best. I mean, at least they didn't choose to revive the film It, your front yard would have been littered with psychopathic clowns with red hair and pointy teeth. It can always be worse, Kimothy. It can always be worse. Well, enough with the candy corn and clowns…what is our pathogen for today? Kimothy: Campylobacter jejuni Christian: Campylobacter is always associated with camping and environmental infections for me. I just remember the camp in Campy and immediately remember that these infections are uncommon for treated water networks, but more likely found in untreated settings like stagnant environmental samples. Kimothy: Yeah, Christian, this bacterium doesn't tend to survive in treated water systems very well; and, if it does, it is in a viable but non-culturable state. This is a gut microbe and it's primarily transmitted through birds, cattle, and other livestock feces – but, poultry mainly, such as chickens and turkeys. Feces from these animals shed campylobacter in into streams, rivers, lakes, and reservoirs. The most common route of infection is through ingestion (fecal-oral), whether that is untreated water or contaminated food. The result is campylobacteriosis – an acute illness that causes nausea, abdominal pain, fever, cramping, and diarrhea. The abdominal pain can be so debilitating that it is often confused with appendicitis. Christian: Alright, so, in treated water there is less of a concern, but it's still possible to become infected in untreated water sources. What about its cellular structure and behavior; is this something I can easily filter out of the water supply I'm drinking from? Kimothy: Well, this is another gram-negative, spiral, and rod-shaped bacterium that is about 0.2um – 0.5um in size, so you'll want a 0.05-micron filter if you want to catch this bug before using the water for consumption. Its motile by a single flagellum, and is not a good biofilm producer, so it's constantly on the move for nutrient sources. It's most happy in intestinal tracts of animals, like I mentioned early, so livelihood is challenging for it in bulk water systems. That said, it doesn't take much ingestion to make you symptomatic and acutely sick. I believe Safewater.org reports that less than 500 cells consumed will result in symptoms. To that end, I'd like to deviate just for a moment and emphasize Campylobacter is the most common bacterial cause of diarrhea in the U.S., affecting 1.5 million residents a year.1 And, a not well-known mode of transmission for shedding Campylobacter is our pets, in particular, our dogs. Christian: Ahhh, so all those people out there that are convinced your dog licking your face is OK, and just a warm sign of affection and love – it's probably true, but it comes with the bonus of acute diarrhea and cramps! Nice. Well, pooches aside, which patient populations are most at risk for acquiring Campylobacter? Kimothy: So, nothing surprising here, Christian. Immunosuppressed or compromised patients are at greatest risk (think cancer and AIDS patients), but also pediatrics -- specifically those under the age of five are highly susceptible because of their lower developed immunity and inability to cope with the hypovolemia and accompanying diarrhea. There are a few rare circumstances possible when acquiring this bacterium that are worth noting also (although these are highly improbable): About one in every 1,000 cases of infection results in Gullian-Barre Syndrome (GBS). GBS is an autoimmune disorder that causes weakness in the extremities and sometimes paralysis. Most people recover, but permanent nerve damage is possible in rare cases. Also, strangely, according to the CDC, about 1-5% of those infected with Campylobacter will develop arthritis – non-age dependent. Christian: Bizarre…I wouldn't have suspected that outcome. Tell me about the treatment. I assume since this is another bacterial pathogen that the best treatment is an antibiotic regimen. Kimothy: Actually, no. This is rarely fatal, and symptoms will usually resolve on their own in most patient populations within about three weeks. Except for those patients most at risk, that I mentioned earlier, you really are just treating the diarrhea here – so taking extra effort to drink lots of fluids and combat the dehydration and cramps is really most of what needs to be done. Christian: Alright, well it's good to hear that this isn't a pathogen with a high mortality rate. It does seem quite easy to acquire in untreated water or contaminated food, but if you do acquire it, symptoms resolve quickly. And the worst-case scenario you must get an antibiotic treatment if you're part of a high-risk patient population. And you said earlier that these little guys don't survive well in bulk water systems and that treated water usually kills them or puts them into a VBNC state. So, there seem to be two easy solutions – use a point-of-use 0.05-micron filter or treat your water – also don't kiss your dog – and you're well on your way to preventing this bacterial infection! Kimothy: Usually it does just come down to the basics. This one is an “easier” one to address, but it still is ubiquitous and it's important to recognize small inputs and changes that really aren't that cumbersome can reduce the infection rate of this opportunistic pathogen. Christian: Alright, Kimothy, another one down, Campylobacter jejuni. I made it through all of that without being campy – well, maybe a little with the dog bit. Kimothy: Yes, a man of true restraint! Christian: Kimothy, as always, thanks so much for the chat today. Kimothy: You bet, Christian. 1 https://www.cdc.gov/campylobacter/faq.html
Don and Professor Ben talk about the risks of eating raw chicken meat sashimi. Dr. Don - risky ☣️ Professor Ben - risky ☣️ Benjamin Schrager on Twitter: “My paper on raw chicken in Japan just got published!! Risky but Raw: On (Not) Regulating One of the Most High-Risk Dishes in Japan Thank you to @Gastronomica for the smooth process and reviewers for their insightful feedback. https://t.co/2mp9FpESDo” / Twitter Risky but Raw | Gastronomica | University of California Press Assessment of the dose-response relationship of Campylobacter jejuni - PubMed
Campylobacteriosis is a disease of worldwide importance, but aspects of its transmission dynamics, particularly risk factors, are still poorly understood. Researchers at the OU Hudson College of Public Health and in Denmark confirm that one of the most common foodborne illnesses in the Western world, can also be spread through sexual contact and their study is published in the journal, Emerging Infectious Diseases. Joining me today to discuss Campylobacter and the research is infectious disease epidemiologist Katrin Kuhn, Ph.D. Dr. Kuhn is an assistant professor in the Department of Biostatistics and Epidemiology in the OU Hudson College of Public Health.
Dr. Don and Professor Ben talk about the risks of cats in the kitchen (on your silver spoon)? Dr. Don - not risky
Greater flexibility is needed in official Salmonella and Campylobacter testing regimes in order to support poultry producers and processors who are trialing new interventions to tackle both pathogens.Dr. Ashley Peterson, PhD, senior vice president of scientific and regulatory affairs, National Chicken Council, said the US poultry industry has made great progress in reducing Salmonella levels to well below the standards set by the USDA's Food Safety and Inspection Service (FSIS).However, because methods for controlling Salmonella might not have similar success with Campylobacter, processors and producers need freedom to trial different interventions without facing punishment if those techniques are not as successful as they hoped.
Blending two commonly used antibacterial treatments could help processing facilities take better control of Campylobacter and reduce the risk of food-borne illnesses, according to scientists.Researchers at Colorado State University found that using a combination of peroxyacetic acid (PAA) and low-pH buffered sulfuric acid is significantly more effective at tackling Campylobacter than using either treatment alone.And they said timing the treatment so it is used after birds are cut up means that reductions in bacterial load could last even longer than when compounds are used individually.Speaking to Poultry Health Today, Keith Belk, PhD, head of the animal science department, said with no vaccines available to control Campylobacter on the farm, the current focus for tackling the pathogen has to be in processing.
Dr. John Greene, Chief of Infectious Diseases at Moffitt Cancer Center, reviews disorders involving the gastrointestinal tract. Syndromes discussed include Cholera, traveller’s diarrhea, Typhoid fever, Salmonellosis, Campylobacter, pathogenic E coli, Echinococcosis, aeromonas, and Vibrio. Dr. Greene presents the topics in a fast paced, photo quiz format.
Dr. Don and Professor Ben talk about the risks of grocery stores stocking ready to eat items in the meat section. Dr. Don - not risky
Acute Gastroenteritis- Author: Dr. Brian Geyer Introduction: Do both vomiting and diarrhea have to be present? No 1996 AAP guidelines, 2016 ACG guidelines, and 2017 IDSA guidelines all note diarrhea illness but may be vomiting predominant. Studies use more vague definitions like: > 1 episode of vomiting and/or > 3 episodes of diarrhea in 24 hours without known chronic cause like inflammatory bowel disease. Diarrhea is at least 3 unformed stools per day. Acute episode 29 days Patients in the ED may present with only some of these symptoms depending their time in course of illness. Literature Review: There is abundant literature on pediatric AGE but sparse research on AGE in adults. Therefore, many recommendations are extrapolated from the pediatric literature. Causes: 70% of US cases are estimated to be caused by viruses, norovirus being most common. o 26% norovirus o 18% rotavirus Among bacterial causes: o 5.3% Salmonella, most common o 5.3% Clostridium o 3% Campylobacter o 3% parasitic infections Large portion, 51%, have no cause identified. (In ED patients) Interestingly, 79% of cases never have a cause identified (not ED specific) In ED patients, only 25% ever have a cause identified, this increases to 49% when a stool sample is obtained. (not ED specific) Food poisoning is responsible for 5% of AGE but results in 30% of deaths. Most commonly: Salmonella, Clostridium perfringens, and Campylobacter Majority of foodborne illness is still viral, mostly norovirus E Coli is normal in the gut, but two most common causes are: Shiga toxin Ecoli (STEC) AKA enterohemorrhagic Ecoli (EHEC) - causes Hemolytic Uremic Syndrome in 5-10% Entertoxigenic Ecoli (ETEC) - causes traveler's diarrhea Both cause self-limited illness. Alternate Diagnoses: Appendicitis: In the peds literature, misdiagnosis of appendicitis as AGE leads to 47% absolute increased risk of perforation. Suggestive findings include: Migration of pain to RLQ RLQ tenderness on exam (initial or repeat) Absence of diarrhea Pain not improved with episodes of diarrhea Negative factors include multiple ill family members, recent international travel, presence of diarrhea (as defined above). Ciguatera Fish Poisoning Toxin produced by algae consumed by reef fish like grouper, red snapper, sea bass and Spanish mackerel. Symptoms begin 6-24 hours post ingestion. Fish tastes normal. Patients may develop neurological symptoms like paresthesias, generalized pruritis, and reversal of hot/cold sensation. Symptoms resolve spontaneously, and treatment with mannitol is controversial. Scombroid Poisoning Ingesting fish in the Scombroidae family - mackerel, bonito, albacore, and skipjack - that have been stored improperly Bacteria produce histidine decarboxylase which converts histidine to histamine Causes abdominal cramps and diarrhea, and may cause metallic bitter or peppery taste in mouth, and facial flushing within 20-30 min of ingestion Can be confused with allergic reaction Symptoms resolve in 6-8 hours Notification of health dept may prevent others from being infected. Page 5 Table 1- Distinguishing Factors in the Differential Diagnosis of AGE History: Table 2, page 6 has key questions to ask. Onset, timing, number of stools, presence of blood, fever, quality of abdominal pain and location, recent antibiotics, etc. Extremes of age, immunosuppression, and pregnancy should be identified. Mortality is highest in the patients >65 yo. Physical Exam: We talked about RLQ abd pain, but what about bloody stool? An observational study of 889 adults and 151 pediatric with AGE showed that a negative fecal occult test showed accurately excluded invasive bacterial etiology with a NPV 87% in adults and 96% in children. But PPV was only 24%.
Today we explore two Gram-negative bacteria. Campylobacter jejuni and Moraxella catarrhalis. For more information please visit: theBradleylab.wordpress.com and follow us on Twitter or Instagram @TheBradleyLab --- Send in a voice message: https://anchor.fm/bradleysmicroboardreview/message Support this podcast: https://anchor.fm/bradleysmicroboardreview/support