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In this encore episode, we detail the intestinal mycobiome and the mechanisms by which beneficial microbes aid in regulating opportunistic fungal species: Candida albicans. We discuss Candida overgrowth virulence and how disruptions in microbial balance, immune function, and epithelial integrity impact Candida's pathogenicity. Additionally, we discuss the role of mast cells in the lamina propria, their involvement in mucosal immunity, and how Mast Cell Activation Syndrome (MCAS) can be exacerbated by fungal dysbiosis / microbial imbalances.Topics: 1. Introduction - The intestinal mycobiome and its role in intestinal health. - Regulating populations of opportunistic fungal species like Candida albicans.- Mast cell activation syndrome (MCAS) intro. 2. Structure of the Intestinal Barrier- The microbiome and mucus layer: microbes, mucins, antimicrobial peptides, sIgA.- The epithelial monolayer: enterocytes, goblet cells, Paneth cells, enteroendocrine cells…- Tight junction proteins and paracellular transport.- The lamina propria beneath the epithelium: immune cells and more. 3. Candida's Pathogenicity and Barrier Disruption- Exists primarily in its yeast form, regulated by microbial competition, host immune defenses, antifungal peptides. - Secretory IgA (sIgA) and immune surveillance mechanisms help regulate fungal populations. - Chronic stress, immune suppression, and dysbiosis can deplete sIgA, increasing susceptibility to Candida proliferation. - Environmental triggers such as immune suppression, microbial depletion, inflammatory cytokines.- Yeast-to-hyphal transition, deeper tissue invasion. - Secreted aspartyl proteinases (SAPs), phospholipases, candidalysin: epithelial damage.- Pattern recognition receptors (PRRs) and overgrowth detection. 4. Impact of Beneficial Bacteria on Candida Overgrowth - Beneficial bacteria compete with Candida for nutrients and epithelial adhesion sites. - Short-chain fatty acids (SCFAs) produced by beneficial bacteria.- Depletion of beneficial bacteria removes ecological resistance, allowing Candida to proliferate unchecked. 5. Mast Cells in the Lamina Propria and Their Role in Intestinal Immunity- Mast cell location - Upon activation, mast cells release histamine, cytokines, proteases, and more that regulate gut immune responses. - Histamine can increase gut permeability and modulate local immune activation. - Tryptase and chymase. - Pro-inflammatory cytokines. 6. Mast Cell Activation Syndrome (MCAS) - Mast cell hyperactivation.- Environmental triggers, toxins, chronic infections, and stress. - Candida overgrowth and mast cell activation.- Addressing microbial imbalances and reducing the body's total microbial, chemical, and toxin burden.- A diverse microbiome. 7. Conclusion- Candida overgrowth and regulation via immune defenses and beneficial bacterial competition.- MCAS, root cause approach.Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
Gene-editing technology which makes pigs immune to a highly infectious virus, developed at Edinburgh University's Roslin Institute, has been approved for use by the US Food and Drug Administration. The virus causes a disease called PRRS or Porcine Reproductive and Respiratory Syndrome, which causes premature births in pigs as well as other painful symptoms and costs the pig industry billions. Current legislation doesn't permit its use in the UK. We speak to one of the scientists who's been working on the project for more than seven years.All week we've been taking a closer look at pulses, the dried seeds of crops like beans, lentils and peas, for both human and animal food. In the UK the peas we eat are generally frozen or fresh but dried peas are a major source of protein to millions of people around the world. Scientists at the John Innes Centre in Norwich have been working with researchers in China, the USA and France to uncover the genome of 700 different varieties of pea, from many different countries, to help develop better commercial varieties.The sudden suspension of England's biggest environmental scheme, the Sustainable Farming Incentive, earlier this year was met with horror and disbelief by farmers and environmentalists alike - we preview a special documentary which charts the transition of agricultural policy from the old EU farm subsidy system and the Common Agricultural Policy to the new 'public money for public goods' approach that we have in England today. Presenter = Caz Graham Producer = Rebecca Rooney
A farmer from southwestern Manitoba is calling for a patient and reasoned response from the federal government to the imposition of reciprocal tariffs by the United States on its trading partners to avoid escalating a brewing trade war.Jim Downey says it's hard to read what's happening in the U.S. from day-to-day but at this point, we still have the ability to trade freely with the United States.Spring offers pork producers an opportunity to take steps to improve biosecurity on their farms. The Swine Health Information Center has identified seasonal decreases in case positivity for PED, delta coronaviruses and mycoplasma; a seasonal decrease in PRRS case positivity, mostly in wean to finish with North Carolina and Iowa; and reporting higher than expected increases in PRRS positive cases and, over the past four years, no positive identification of transmissible gastroenteritis. SHIC Associate Director Dr. Lisa Becton says the warmer weather is welcome.See omnystudio.com/listener for privacy information.
In this episode, we detail the intestinal mycobiome and the mechanisms by which beneficial microbes aid in regulating opportunistic fungal species: Candida albicans. We discuss Candida overgrowth virulence and how disruptions in microbial balance, immune function, and epithelial integrity impact Candida's pathogenicity. Additionally, we discuss the role of mast cells in the lamina propria, their involvement in mucosal immunity, and how Mast Cell Activation Syndrome (MCAS) can be exacerbated by fungal dysbiosis / microbial imbalances.Topics: 1. Introduction - The intestinal mycobiome and its role in intestinal health. - Regulating populations of opportunistic fungal species like Candida albicans.- Mast cell activation syndrome (MCAS) intro. 2. Structure of the Intestinal Barrier- The microbiome and mucus layer: microbes, mucins, antimicrobial peptides, sIgA.- The epithelial monolayer: enterocytes, goblet cells, Paneth cells, enteroendocrine cells…- Tight junction proteins and paracellular transport.- The lamina propria beneath the epithelium: immune cells and more. 3. Candida's Pathogenicity and Barrier Disruption- Exists primarily in its yeast form, regulated by microbial competition, host immune defenses, antifungal peptides. - Secretory IgA (sIgA) and immune surveillance mechanisms help regulate fungal populations. - Chronic stress, immune suppression, and dysbiosis can deplete sIgA, increasing susceptibility to Candida proliferation. - Environmental triggers such as immune suppression, microbial depletion, inflammatory cytokines.- Yeast-to-hyphal transition, deeper tissue invasion. - Secreted aspartyl proteinases (SAPs), phospholipases, candidalysin: epithelial damage.- Pattern recognition receptors (PRRs) and overgrowth detection. 4. Impact of Beneficial Bacteria on Candida Overgrowth - Beneficial bacteria compete with Candida for nutrients and epithelial adhesion sites. - Short-chain fatty acids (SCFAs) produced by beneficial bacteria.- Depletion of beneficial bacteria removes ecological resistance, allowing Candida to proliferate unchecked. 5. Mast Cells in the Lamina Propria and Their Role in Intestinal Immunity- Mast cell location - Upon activation, mast cells release histamine, cytokines, proteases, and more that regulate gut immune responses. - Histamine can increase gut permeability and modulate local immune activation. - Tryptase and chymase. - Pro-inflammatory cytokines. 6. Mast Cell Activation Syndrome (MCAS) - Mast cell hyperactivation.- Environmental triggers, toxins, chronic infections, and stress. - Candida overgrowth and mast cell activation.- Addressing microbial imbalances and reducing the body's total microbial, chemical, and toxin burden.- A diverse microbiome. 7. Conclusion- Candida overgrowth and regulation via immune defenses and beneficial bacterial competition.- MCAS, root cause approach.Thank you to our episode sponsor:1. Shop Fresh Press Farms'Peach Cider Vinegar at Sprouts locations nationwide, and check out their full collection here. Get Chloe's Book Today! "75 Gut-Healing Strategies & Biohacks" Follow Chloe on Instagram @synthesisofwellnessVisit synthesisofwellness.com
In this episode of The Squeal, host Dr. Lindsay Case (PIC Technical Director of Product Sustainability) continues the conversation on the future of the PRRS-resistant pigs in consumer markets. Joining her are Marisa Pooley (PIC Director of Communications & Engagement) and Staci Covkin (Circana, Principal of Innovation Consumer & Shopper Insights), two experts in communications and consumer perception. They explore how gene-edited livestock fits into the evolving food landscape, addressing public perception, and the role of transparent communication in building consumer trust.
Matters Microbial #81: Viruses, Innate Immunity, and Undergraduates March 5, 2025 Today, Dr. Brianne Barker, Associate Professor of the Biology Department at Drew University, joins the #QualityQuorum to discuss how her undergraduate research group studies how innate immune mechanisms of cells recognize viral invasion. Host: Mark O. Martin Guest: Brianne Barker Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A video describing the immune system, both innate and adaptive. More of a focus on mechanisms of innate immunity, the focus for today. A description of basic immune cells. An introductory video describing the viral reproductive cycle in general. A description of PRRs (pattern recognition receptors) and MAMPs (microbially associated molecular patterns) An overview of interferons and disease. An introductory video overview of programmed cell death, called apoptosis. The role that retroviruses play in producing blue eggs in chickens. Here is a very introductory summary. The role that retroviruses play in placental mammals, including humans. How do cells recognize invading DNA during viral infection? A research paper by Dr. Barker's research group. Dr. Barker on This Week in Virology. Dr. Barker's faculty website. Dr. Barker's research group website. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com
On today's episode of The Squeal, our host, Dr. Lindsay Case (PIC Technical Director, Product Sustainability) is joined by Marisa Pooley (PIC Director of Communications and Engagement) and Staci Covkin (Principal, Innovation Consumer & Shopper Insights - Circana.) The guests share insights into consumer acceptance in anticipation of the PRRS-Resistant Pig.
In this month's PigX episode, we look into research to identify the health status of pigs - especially for PRRS – utilizing key performance indicators.. Researchers have developed a formula to help detect diseases earlier, offering a tool that facilitates faster and potentially more cost-effective data analysis compared to investing in additional farm technologies. Joining us from Iowa State University are Drs. Gustavo Silva, an assistant professor in Veterinary Diagnostic and Production Animal Medicine, and Mafalda Mil-Homens, a PhD student and veterinarian. They share insights from their global experiences and how these have influenced their work in the Midwest swine industry.
The spread of high-risk human and animal diseases across borders in the last five years has clearly demonstrated that the best-laid plans can go wrong when it comes to infectious disease control and prevention. In fact, North American and European countries proved decades ago that swine diseases like ASF and classical swine fever can be eradicated through effective government policies, even without ideal vaccines. However, the world has since changed.Joining our Ann Hess to discuss this topic and more from the PRRS Symposium in Chicago is Dr. Jishu Shi of Kansas State University. Dr. Jishu Shi's research team develops vaccine adjuvants, novel diagnostic assays and vaccines for swine infectious diseases. Specifically, his team focuses research on African swine fever (ASF), Streptococcus suis, swine influenza virus (SIV), classical swine fever (CSF), porcine reproductive and respiratory syndrome (PRRS), and other emerging infectious diseases of swine.This episode of Feedstuffs in Focus is sponsored by United Animal Health, a leader in animal health and nutrition. You can learn more about United Animal Health and how they are working to advance animal science worldwide by visiting the website at UnitedANH.com
Grain and livestock markets are mixed early. Scott Varilek, Kooima Kooima Varilek, says cattle are trying to recover after a poor technical close yesterday with the help of strong cash. Hogs are consolidating but the funds may continue to buy the breaks with talk of PRRS. Corn is higher, with March breaking above $4.35 resistance with strong demand and ideas of lower ending stocks in next week's WASDE. However, he says a close above this level may only result in another 5 cent higher move as the market still doesn't have the bullish catalyst to support a bigger rally. Soybeans consolidate after a higher day yesterday with China buying rumors supporting the market, but with no confirmation of any business and continued higher estimates for Brazil's crop futures are setting back. See omnystudio.com/listener for privacy information.
Como es habitual de mi parte, cada trimestre te hago un resumen con las principales perspectivas globales de la carne de cerdo y a continuación te las dejo: La expansión de la industria porcina sigue siendo moderada debido a incertidumbres relacionadas con el comercio, enfermedades y demanda de consumo. Los desafíos políticos y comerciales, como cambios en administraciones clave y regulaciones regionales, podrían dificultar el comercio en 2025. Costos y Producción: La caída de los costos de alimento (maíz y soya) ha mejorado los márgenes en varias regiones, aunque La Niña podría generar impactos desiguales en los costos de producción. La producción porcina se mantiene estable globalmente, con incrementos modestos en regiones como Brasil y el sur de la UE, mientras que Europa y Asia enfrentan presiones regulatorias y de enfermedades. Consumo y Comercio: Se proyecta un aumento estacional del consumo de carne de cerdo impulsado por menores costos de energía y una mejora en la confianza del consumidor en algunas regiones. China muestra señales de recuperación en la demanda tras estímulos económicos, pero su investigación antidumping sobre la UE podría alterar los flujos comerciales. Los precios del cerdo mejoraron en la mayoría de las regiones, reflejando un mejor equilibrio entre oferta y demanda. Desafíos Regionales: En América del Norte, el mercado sigue saturado, pero la mejora en la salud de las granjas y costos más bajos benefician a los productores. Europa enfrenta obstáculos regulatorios y desafíos de enfermedades, como el PRRS y peste porcina africana, que afectan la expansión del sector. En el Sudeste Asiático, las enfermedades continúan impactando la producción, pero se espera una recuperación lenta en países como Filipinas. Precios y Producción: Los precios de los cerdos en México han normalizado tras un verano volátil, ubicándose en MXN 39.55/kg en el tercer trimestre de 2024. La productividad mejoró en el segundo semestre de 2024, lo que estabilizó el suministro. Se espera un crecimiento moderado del 1% interanual en 2025. Importaciones: Las importaciones de carne de cerdo crecieron un 5.6% interanual hasta julio de 2024, con aumentos de doble dígito desde Estados Unidos y Canadá. Las importaciones de Brasil casi se duplicaron (+81%), beneficiándose del acceso sin aranceles, aunque representan solo el 2% del volumen total importado. A pesar de la devaluación del peso mexicano (8.4% interanual), la demanda de cerdo importado se mantiene fuerte. Consumo y Preferencias del Mercado: El consumo de carne de cerdo sigue en crecimiento debido a la preferencia de los consumidores mexicanos por esta proteína. Se observó una tendencia hacia productos de valor agregado, como cortes deshuesados y pre-cocinados, en respuesta a la demanda de conveniencia. Factores Económicos y Políticos: La devaluación del peso frente al dólar podría superar los MXN 20/USD hacia fin de año. La reciente administración de Claudia Sheinbaum asumió en octubre de 2024; aunque no se esperan cambios inmediatos en la política económica o agrícola, podría haber impacto en las importaciones. Precios y Producción: Los precios del cerdo se moderaron al cierre del tercer trimestre, tras un periodo de aumento, con precios de CNY 17.5/kg (cerdos vivos) y CNY 30/kg (lechones). Se espera que los precios se mantengan fuertes en el cuarto trimestre debido al suministro limitado y a la demanda estacional alta. La producción muestra un leve declive, compensado parcialmente por el aumento en los pesos de sacrificio y mejoras en productividad. Importaciones: Las importaciones de carne de cerdo cayeron un 24% interanual hasta agosto, aunque repuntaron levemente en julio y agosto por precios locales más altos. La investigación antidumping de China contra la UE podría derivar en aranceles provisionales, afectando los flujos comerciales y elevando los precios locales. Consumo: El consumo de cerdo se mantiene estable, impulsado por estímulos gubernamentales durante festividades nacionales como la Semana Dorada. Se espera que nuevos estímulos económicos impulsen aún más la demanda. Rebaño y Bioseguridad: El inventario de cerdas aumentó ligeramente (+0.1% mensual en julio), aunque sigue un 5.4% por debajo del nivel interanual. Las actividades de bioseguridad son prioritarias, pero los pequeños productores se centran más en engorde a corto plazo que en expansión de rebaños. Vietnam: Los precios de los cerdos vivos permanecen altos, oscilando entre VND 62,000 y VND 69,000/kg, un aumento del 15% interanual. El suministro sigue ajustado, y la demanda crece junto con la economía, que tuvo un crecimiento del 6.8% del PIB en los primeros nueve meses de 2024. Las importaciones de carne de cerdo aumentaron en volumen, con Brasil, Rusia y Canadá como principales proveedores. Filipinas: La producción sigue afectada por brotes de peste porcina africana (ASF), con una disminución del 5.6% interanual en el inventario al cierre de junio. Los precios subieron un 12.8% interanual en el segundo trimestre. Las importaciones crecieron un 39.5% interanual en la primera mitad de 2024, con Brasil liderando como principal proveedor. Tendencias Regionales: Los brotes de enfermedades siguen siendo un desafío significativo en la región, aunque con menor severidad que en periodos anteriores. La recuperación económica en países clave del sudeste asiático está impulsando un crecimiento más rápido en el consumo de carne de cerdo A tu lado en la visión estratégica del mercado porcino, Reinaldo Cubillos MéxicoChina:Sudeste Asiático:
Eric Broser has been involved in the health and fitness industry as a trainer, strength/contest prep coach, model, author, magazine columnist, consultant to nutritional supplement companies and gym owner for over twenty-five years.He is a formerNatural Professional Bodybuilder, contest judge and now NPC Masters Competitor. Eric has penned over 1000 articles (for web and print) on training, supplements, mindset and nutrition, which have appeared in such major publications as Flex, Iron Man, Planet Muscle, Natural Muscle, Muscular Development, Muscle Mag International, Human Muscle and Performance, UCW and Muscular Health and Performance Illustrated.He is currently a monthly columnist for FLEX, IronMan, Natural Muscle and www.muscleandfitness.com, and has authored four books on the subject of rapid and substantial physique transformation. Eric is the pioneer/developer of the world-renown POWER-REP RANGE-SHOCK™, O-BEY-6™, FTX2™, ESPX2™ and FIBER DAMAGE/FIBER SATURATION™ training methods, which are being utilized by tens of thousands of bodybuilders and athletes across the globe. The PRRS™ DVD was a best seller for well over five years, while the PRRS™ and FDFS™ E- books are still getting downloaded daily.Being featured on the cover of Iron Man in October 2008 fulfilled one of Eric's lifelong dreams. He has also appeared in the pages of just about every major fitness/bodybuilding magazine as a model, writer or subject of dozens of supplement company advertisements. In May 2010, and again in 2011, he was awarded the honor of being named the "Top Trainer/Author Combination" by Planet Muscle Magazine.
Send us a textEpisode Overview:In this special replay from The Real P3, celebrating #Porktober24, Coffee in the Barn brings you a unique episode featuring Philip and Dr. Andrew Tucker, a seasoned swine veterinarian from South Africa. As they travel through Zimbabwe, they discuss swine health and production across Africa, addressing the diverse challenges and opportunities faced by farmers on the continent.The conversation delves into essential topics such as biosecurity in pig farming, the need for stringent disease prevention measures, and the inspiring story of how pig carcasses are used to help feed endangered vultures in a conservation initiative known as "buzzard cafes." Dr. Tucker shares his insights into the practical realities of farming in Africa, the severe impact of power outages on agriculture, and the incredible resilience of farmers dealing with these issues.With over 20 years of experience in the field, Dr. Tucker's passion for pig farming began on his family's piggery in South Africa. Now working across the continent, he implements cutting-edge biosecurity protocols to prevent diseases like African Swine Fever (ASF). Dr. Tucker stresses the importance of strict "shower in, shower out" practices and pathogen-free farming in areas where diseases such as mycoplasma, PRRS, and ASF pose significant risks to pig health and production.Highlights from the conversation:Biosecurity: Dr. Tucker explains how farms in Zimbabwe and South Africa are SPF (Specific Pathogen-Free), and the strict protocols they follow to prevent diseases like ASF, mycoplasma, and swine dysentery.Innovative Waste Management: Dr. Tucker talks about "vulture restaurants," where pig mortalities are used to feed endangered vultures. This practice helps preserve the birds while preventing the spread of disease.African Pig Farming Challenges: From navigating dangerous roads in Nigeria to handling the economic impacts of power outages and rising grain prices, Dr. Tucker provides insight into the resilience and resourcefulness of African pig farmers.One of the most unique aspects of the episode is Dr. Tucker's work with vulture conservation. These “vulture restaurants” supply food to critically endangered birds while also addressing farm waste management. This innovative practice contributes to wildlife preservation and demonstrates how pig farming can positively impact the environment.Dr. Tucker also highlights African farmers' economic pressures, mainly due to rising grain prices and power cuts. Despite these challenges, his optimism about the future of African agriculture shines through, emphasizing how farmers adapt and find innovative solutions.Tune in to this #Porktober24 episode to explore how African pig farms embrace sustainability, strengthen biosecurity, and contribute to conservation efforts—all while navigating the complexities of modern pig farming.Support the showConnect with us on Facebook, Instagram and LinkedIn:@cofeeinthebarn
The last time the estimated economic impact of porcine reproductive and respiratory syndrome virus, or PRRS, was investigated was in 2013. What is the current impact of the disease on herd health and production? Feedstuffs Ann Hess caught up with Drs. Henry Osemeke and Derald Holtkamp of Iowa State University during this week's Iowa Swine Day to find out more.This episode of Feedstuffs in Focus is sponsored by United Animal Health, a leader in animal health and nutrition. You can learn more about United Animal Health and how they are working to advance animal science worldwide by visiting the website at UnitedANH.com
Join Dr. Spencer Wayne and Dr. Cameron Schmitt in a discussion of the ever-evolving landscape of swine diseases. In this episode, Dr. Schmitt, Executive Vice President of Pipestone Veterinary Services, delves deep into the nuances of various pathogens affecting swine health today. From the notorious PRRS virus to resilient strains of E. coli, they dissect the challenges and advancements in disease management strategies. The pair begin the discussion with the infamous diseases sharing insights and practical advice, then transition to a few emerging viruses. With their down-to-earth approach, you'll gain a clearer understanding of the ongoing battle to safeguard swine well-being.
In this episode, we explore the transformative advancements in pork production with Banks Baker of PIC. Consumer expectations for high animal care standards, antimicrobial stewardship, and sustainable practices are reshaping the food industry. Innovative solutions and technologies are emerging to meet these demands, fostering sustainable food production. Gene editing plays a pivotal role in enhancing animal health and aligns with antibiotic stewardship goals in pork production. Baker discusses the potential impact of gene editing on preventing diseases like PRRS and how it parallels successful applications in human healthcare. Challenges and considerations in applying this technology to animal agriculture, particularly in protecting pigs from diseases, are also explored. PIC's groundbreaking development of a PRRS-resistant pig through gene editing is highlighted, offering broader implications for pig herd health and the significant reduction of antibiotic use. Navigating global regulatory systems presents challenges and opportunities for PIC, and Baker sheds light on the company's approach to gaining approvals worldwide. Join us in this episode as we delve into the future of pork production, where cutting-edge technologies and sustainable practices are reshaping the industry landscape.
Porcine reproductive and respiratory syndrome (PRRS) is a significant disease and cost the swine industry some $660 million annually. For multiple decades, the industry has had its hands tied when it comes to PRRS but new research out of Pipestone shows that may no longer be the case, and in fact, producers may now the ones in charge of the virusJoining us to share newly released details on a study looking at whether the application of a comprehensive, science-based approach to breeding herd biosecurity, known as next-generation biosecurity, could reduce the PRRS risk across a large commercial production company is Dr. Scott Dee.For more information: javma-javma.23.08.0437.pdfThis episode of Feedstuffs in Focus is sponsored by United Animal Health, a leader in animal health and nutrition. You can learn more about United Animal Health and how they are working to advance animal science worldwide by visiting the website at UnitedANH.com
In the podcast, Swine Extension Educator Sarah Schieck Boelke speaks with Ph.D. student Marcello Melini about his research on environmental sampling of farm surfaces to assess contamination of PRRS (Porcine Reproductive and Respiratory Syndrome) virus at various places both in and outside the barn.
SwineCast 1254 Show Notes: U.S. swine producers will face continued economic challenges for the first portion of 2024, with a reduction in feed costs arriving by summer. But producers will still need to improve herd health and make their production systems more efficient if they are to survive. The At The Meeting team welcomes back …
SwineCast 1254 Show Notes: U.S. swine producers will face continued economic challenges for the first portion of 2024, with a reduction in feed costs arriving by summer. But producers will still need to improve herd health and make their production systems more efficient if they are to survive. The At The Meeting team welcomes back …
SwineCast 1253 Show Notes: The US Swine Health Improvement Plan (US-SHIP), with its House of Delegates and recently elected General Conference Committee (GCC), provides an action-oriented structure to safeguard and improve the health of the U.S. swine herd. The At The Meeting team talks with US-SHIP senior coordinator Dr. Tyler Holck (Iowa State University), and …
SwineCast 1253 Show Notes: The US Swine Health Improvement Plan (US-SHIP), with its House of Delegates and recently elected General Conference Committee (GCC), provides an action-oriented structure to safeguard and improve the health of the U.S. swine herd. The At The Meeting team talks with US-SHIP senior coordinator Dr. Tyler Holck (Iowa State University), and …
SwineCast 1252 Show Notes: The absence of improved standards for tracing the movement of pigs in the U.S. is producing unnecessary risk for producers and the industry. While an estimated 70 percent of producers favor improved traceability, near unanimous adoption is needed to reassure U.S. trade partners and protect producer income in the event of …
SwineCast 1252 Show Notes: The absence of improved standards for tracing the movement of pigs in the U.S. is producing unnecessary risk for producers and the industry. While an estimated 70 percent of producers favor improved traceability, near unanimous adoption is needed to reassure U.S. trade partners and protect producer income in the event of …
There is no right answer when it comes to porcine reproductive and respiratory syndrome, but controlling the virus in the early days requires PRRSv herd stabilization and herd closure to be part of the conversation. In this episode, Dr. Paul Yeske, Swine Vet Center, walks us through different strategies producers can use in the field to control and eliminate PRRS L1C. Our Ann Hess sat down with Dr. Yeske at this past weekend's PRRS conference in Chicago, IL.This episode is sponsored by United Animal Health, a leader in animal health and nutrition. You can learn more about United Animal Health and how they are working to advance animal science worldwide by visiting the website at UnitedANH.comFor more information on this and other topics, we invite you to visit our websites - www.beefmagazine.com, www.Feedstuffs.com, and www.NationalHogFarmer.com.
In the podcast Swine Extension Educator Sarah Schieck Boelke speaks with PhD student Marcello Melini about his research on the infectivity of PRRS virus variant 1-4-4 as it comparies to other PRRS virus variants. The podcast was recorded on October 20, 2023.
SwineCast 1251 Show Notes: Recruiting the next generation of swine veterinarians is challenging, which puts the future of swine health at risk. The At The Meeting team talks with Dr. Chris Richards (Managing Director, Apiam Animal Health) about how Apiam has successfully used mentorships, career planning, flexible workplace practices, student debt reduction, and other tools …
SwineCast 1251 Show Notes: Recruiting the next generation of swine veterinarians is challenging, which puts the future of swine health at risk. The At The Meeting team talks with Dr. Chris Richards (Managing Director, Apiam Animal Health) about how Apiam has successfully used mentorships, career planning, flexible workplace practices, student debt reduction, and other tools …
Joining the PigX Podcast this month are Dr. Chris Rademacher, a Swine Extension Veterinarian and the AssociateDirector for the Iowa Pork Industry Center, and Dr. Daniel Linhares, an Associate Professor and theDirector of Graduate Education for Iowa State University's College of Veterinary Medicine. Take a listen to hear Chris and Daniel discussing past outbreak management programs for the PRRS virus.
SwineCast 1250 Show Notes: The Swine Disease Reporting System (SDRS) invited Dr. Gustavo Silva (Iowa State University) to discuss the importance of disease diagnostics for production management and the cost of Mycoplasma hyopneumoniae elimination. This SwineCast episode shares the most recent report number 68, that can also be found at https://fieldepi.research.cvm.iastate.edu/sdrs/.
PRRS is currently the most economically debilitating disease in the swine industry costing hundreds of millions of dollars in losses each year. Due to this impact, multiple organizations are working toward a gene-edited PRRS resistant pig. We're joined by Dr. Chris Rademacher from Iowa State University and the Iowa Pork Industry Center to discuss the path forward for this technology.
Production costs continue to climb across the swine industry, and the health costs associated with porcine reproductive and respiratory syndrome only make it worse. PRRS is estimated to cost the industry $1.8 million per day.Host Sarah Muirhead talks with Dr. Katie Coleman from Iowa Select Farms to discuss how Iowa Select reduced PRRS incidence by more than 90% in affected barns, without building new barns in a swine-dense area. They discuss: Costs of PRRS to a systemA specific type of filtration addition that didn't require a new barn buildTimeline necessary for modifications and culture shiftHow improved herd health benefits employeesTools they used and lessons learnedThis podcast is one of a four-part series on controlling costs with herd health, which is brought to you by Pharmgate Animal Health. Check out the other three episodes for discussions on Mycoplasma hyopneumoniae, Lawsonia and porcine sapovirus. Call your Pharmgate representative or visit pharmgate.com to learn about their broad portfolio of options to support your protocols.
In this episode of The Round Barn Podcast, Dr. Jim Lowe and Kaylee Hillinger discuss gene editing and its potential to revolutionize animal welfare and agriculture. The hosts explain the difference between gene editing and genetic modification and explore the recent advancements in CRISPR technology. They highlight the progress made in creating disease-resistant animals, such as PRRS-resistant pigs and BVD-resistant cattle, and the potential to enhance animal welfare by reducing the incidence of diseases that cause suffering and mortality. Additionally, the conversation touches on the environmental advantages of gene editing, including reduced antibiotic use and carbon consumption, as well as the potential to enhance sustainability in the food system. They also chat about the commercialization and scaling challenges faced by gene editing technology and the importance of transparency and consumer education. After the podcast, connect with us on LinkedIn by following: The Round Barn at Illinois or visit online at vetmed.illinois.edu/ope2 to discover additional learning opportunities!
There are plenty of diseases that can affect a production system, but what happens when the standard culprits don't show up on a diagnostics test? Host Sarah Muirhead sits down with Dr. Tom Petznick of ArkCare to discuss lessons learned in uncovering and controlling porcine sapovirus.They discuss: Realizing he was dealing with a new challengeNext generation gene sequencingTreatments for a little known virusThe costs of sapovirus to a systemLessons learned from a sneaky virusDr. Petznick, veterinarian at ArkCare, has been practicing swine veterinary medicine for 25 years and is this year's Allen D. Leman Science in Practice Award winner. His expertise in managing purebred sows has made him an in-demand consulting swine veterinarian.This podcast is one of a four-part series on controlling costs with herd health brought to you by Pharmgate Animal Health. Check out the other three episodes for discussions on PRRS, Mycoplasma hyopneumoniae and Lawsonia. Call your Pharmgate representative or visit pharmgate.com to learn about their broad portfolio options to support your protocols.
SwineCast 1249 Show Notes: Decreases in pork production in other EU countries have created growth opportunities for Spanish pork producers, but the potential for increasing regulation and declining consumption of pork are causing concern. Both threats could drive significant declines in EU pork production in the years ahead. The ATM team discusses the situation with …
SwineCast 1249 Show Notes: Decreases in pork production in other EU countries have created growth opportunities for Spanish pork producers, but the potential for increasing regulation and declining consumption of pork are causing concern. Both threats could drive significant declines in EU pork production in the years ahead. The ATM team discusses the situation with …
SwineCast 1248 Show Notes: Tim Heiller with PIC shares how the DISC Personality Test can help teams work better together.
Dr. Spencer Wayne welcomes Dr. Adam Schelkopf, Health Director for Pipestone Management, for a discussion on the overall health status of PIPESTONE-managed farms. Historically, this time of year brings an increase in illness, especially PRRS infections. Dr. Schelkopf reports less than 10% of PIPESTONE-managed farms breaking with PRRS over the last two years, which is far better than in the past. He attributes the improvement to compounding interventions over time. Feed mitigation is the most recent strategy implemented at PIPESTONE, having been in place for 2-3 years it correlates well to the reduction in PRRS over the last two years. Over the last 15 years air filtration has been implemented in nearly 70% of farms. And lastly, location selection. The good health reported from an isolated sow farm pays dividends. In regard to the wean-to-finish side, Dr. Schelkopf stresses the importance of alternatives to antibiotics – management, environment, sanitation, and biosecurity. Though the availability of generic drugs may be greater, the introduction of new antibiotics is not expected. Dr. Schelkopf recommends this recipe for success: “Start with a high-health pig and protect it through the wean-to-market phase with biosecurity.” PIPESTONE's mission is "Helping Farmers Today Create the Farms of Tomorrow." The SwineTime podcast was created for pig farmers and individual pork producers around the country. Hosted by Dr. Wayne, the podcast contains pork industry news, advancements in animal care, and how to enhance your productivity. Monthly podcasts are available on Spotify, Google Music, iTunes, and on Pipestone.com.
In an industry where health challenges can determine the difference between profitability and loss, why not eliminate a challenge when you can? Host Sarah Muirhead sits down with Dr. Amy Maschhoff from The Maschhoffs LLC System to discuss practical strategies, lessons and benefits seen from eliminating M. Hyo, a common cause of coinfections.They discuss: Costs of mycoplasma to a systemLessons learned from eliminating the diseaseBenefits to the production system as a wholeBackup plans if the original elimination plan doesn't workFuture opportunitiesDr. Amy Maschhoff is the director of health and animal care for The Maschhoffs, LLC. She earned her veterinary degree from the University of Illinois Urbana-Champaign and began her career as herd veterinarian for The Maschhoffs. Now she serves in a more central role for the Maschhoff system.This podcast is one of a four-part series on controlling costs with herd health brought to you by Pharmgate Animal Health. Check out the other three episodes for discussions on PRRS, Lawsonia and porcine sapovirus. Call your Pharmgate representative or visit pharmgate.com to learn about their broad portfolio of options to support your protocols.
SwineCast 1247 Show Notes: Dr. Dusty Oedekoven (Chief Veterinarian, National Pork Board) toured the European Union and surrounding countries to learn more about how African Swine Fever (ASF) is managed. Key takeaway: The EU has zone standardization language and practices in place for regions with ASF. This standard helps provide bio-containment, bio-exclusion, and supports business …
SwineCast 1246 Show Notes: Dr. Meredith Petersen (Iowa State University Swine Medicine Education Center) shares a research update on veterinary telehealth and telemedicine. Key message is telehealth offers an opportunity for improving veterinary efficiency but the current telehealth equipment needs improvement.
SwineCast 1245 Show Notes: The Swine Disease Reporting System (SDRS) invited Dr. Craig Bowen (Purdue University) to discuss Purdue’s Animal Disease Diagnostic Laboratory contributions, motivations to join the SDRS project, and the expected benefits for swine stakeholders. This SwineCast episode shares the most recent report number 67, that can also be found at https://fieldepi.research.cvm.iastate.edu/sdrs/.
SwineCast 1244 Show Notes: The Swine Disease Reporting System shares aggregate data from participating veterinary diagnostic laboratories (VDLs) in the United States of America. Plus Dr. Thomas Petznick (ArkCare) joins the conversation on the PRRSV scenario in Nebraska, enteric coronavirus biosecurity strategies, and Sapovirus epidemiology. This SwineCast episode shares the most recent report number 66, …
SwineCast 1243 Show Notes: With several successful California Prop 12 certifications behind her, Dr. Cara Haden from Pipestone Veterinary Services has important insights about the compliance process. She shares with the At The Meeting team how important detailed documentation is to the Prop 12 certification process. On ‘At the Meeting’, Honoring Dr. Bob Morrison are …
SwineCast 1242 Show Notes: The Swine Disease Reporting System team discusses the project’s new developments funded from the USDA’s National Institute of Food and Agriculture (NIFA). New developments include monitoring new PRRSV variants, traceability of pathogen co-detections, and SDRS representativeness. This SwineCast episode shares the most recent report number 65, that can also be found …
SwineCast 1241 Show Notes: The European Union swine producers are facing challenging headwinds related to economics, environmental concerns, and perceptions of livestock conditions. Is this an opportunity for U.S. producers or a foreshadowing of the future? The At The Meeting team talks with Dr. Oliver Duran (Boehringer Ingelheim Leader for the Swine Technical Services Team) …
SwineCast 1240 Show Notes: Dr. Rodger Main (Professor & Director, Iowa State University Veterinary Diagnostic Laboratory) shares updates on Iowa State University Veterinary Diagnostic Laboratory and what it will do to help food animal health monitoring in Iowa and across the U.S.
SwineCast 1239 Show Notes: The Swine Disease Reporting System team features special guest Dr. Pablo Pineyro (Iowa State University) to discuss discusses PCV2 monitoring strategies. This SwineCast episode shares the most recent report number 64, that can also be found at https://fieldepi.research.cvm.iastate.edu/sdrs/.
Senator Ron Johnson sent letters to the CDC three times in 2022, seeking clarity on the agency's monitoring of COVID-19 vaccine adverse events. In a June 2022 reply, the CDC claimed not to have conducted a Proportional Reporting Ratio analysis. However, a CDC official from the agency's Vaccine Safety Team contradicted this in July 2022, saying the CDC had been performing PRRs since Feb 2021 and continues to do so. If the science is on their side, why is the CDC working so hard to hide mRNA vaccine injury data? ABOUT SENATOR RON JOHNSON Senator Ron Johnson from Wisconsin was elected in 2010. He served as the Chairman of the Homeland Security and Governmental Affairs Committee from 2015-2021 and is now the ranking member for the Permanent Subcommittee on Investigations. He also serves on the Budget, Foreign Relations, and Commerce, Science and Transportation committees. Follow him at https://Twitter.com/RonJohnsonWI or his official government account at https://Twitter.com/SenRonJohnson. 「 SPONSORED BY 」 • BIRCH GOLD - Don't let your savings lose value. You can own physical gold and silver in a tax-sheltered retirement account, and Birch Gold will help you do it. Claim your free, no obligation info kit from Birch Gold at https://birchgold.com/drew • GENUCEL - Using a proprietary base formulated by a pharmacist, Genucel has created skincare that can dramatically improve the appearance of facial redness and under-eye puffiness. Genucel uses clinical levels of botanical extracts in their cruelty-free, natural, made-in-the-USA line of products. Get 10% off with promo code DREW at https://genucel.com/drew 「 MEDICAL NOTE 」 The CDC states that COVID-19 vaccines are safe, effective, and reduce your risk of severe illness. Hundreds of millions of people have received a COVID-19 vaccine, and serious adverse reactions are uncommon. Dr. Drew is a board-certified physician and Dr. Kelly Victory is a board-certified emergency specialist. Portions of this program will examine countervailing views on important medical issues. You should always consult your personal physician before making any decisions about your health. 「 ABOUT the SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (https://kalebnation.com) and Susan Pinsky (https://twitter.com/firstladyoflove). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. 「 GEAR PROVIDED BY 」 • BLUE MICS - Find your best sound at https://drdrew.com/blue • ELGATO - See how Elgato's lights transformed Dr. Drew's set: https://drdrew.com/sponsors/elgato/ 「 ABOUT DR. DREW 」 For over 30 years, Dr. Drew has answered questions and offered guidance to millions through popular shows like Celebrity Rehab (VH1), Dr. Drew On Call (HLN), Teen Mom OG (MTV), and the iconic radio show Loveline. Now, Dr. Drew is opening his phone lines to the world by streaming LIVE from his home studio. Watch all of Dr. Drew's latest shows at https://drdrew.tv Learn more about your ad choices. Visit megaphone.fm/adchoices
Videos: 6ft Social Distancing "Made Up": HHS Insider Dr. Paul Alexander w/ Dr. Kelly Victory – Ask Dr. Drew (13:00) Lara Logan & Sasha Latypova on DoD VAXX Coverup /w FDA Theater (START @ 1:12) CDC Finally Released Its VAERS Safety Monitoring Analyses for COVID Vaccines via FOIA And now it's clear why they tried to hide them. Josh Guetzkow Jan 4, 2023 SUMMARY CDC's VAERS safety signal analysis based on reports from Dec. 14, 2020 – July 29, 2022 for mRNA COVID-19 vaccines shows clear safety signals for death and a range of highly concerning thrombo-embolic, cardiac, neurological, hemorrhagic, hematological, immune-system and menstrual adverse events (AEs) among U.S. adults. There were 770 different types of adverse events that showed safety signals in ages 18+, of which over 500 (or 2/3) had a larger safety signal than myocarditis/pericarditis. The CDC analysis shows that the number of serious adverse events reported in less than two years for mRNA COVID-19 vaccines is 5.5 times larger than all serious reports for vaccines given to adults in the US since 2009 (~73,000 vs. ~13,000). Twice as many mRNA COVID-19 vaccine reports were classified as serious compared to all other vaccines given to adults (11% vs. 5.5%). This meets the CDC definition of a safety signal. There are 96 safety signals for 12-17 year-olds, which include: myocarditis, pericarditis, Bell's Palsy, genital ulcerations, high blood pressure and heartrate, menstrual irregularities, cardiac valve incompetencies, pulmonary embolism, cardiac arrhythmias, thromboses, pericardial and pleural effusion, appendicitis and perforated appendix, immune thrombocytopenia, chest pain, increased troponin levels, being in intensive care, and having anticoagulant therapy. There are 66 safety signals for 5-11 year-olds, which include: myocarditis, pericarditis, ventricular dysfunction and cardiac valve incompetencies, pericardial and pleural effusion, chest pain, appendicitis & appendectomies, Kawasaki's disease, menstrual irregularities, vitiligo, and vaccine breakthrough infection. The safety signals cannot be dismissed as due to “stimulated,” exaggerated, fraudulent or otherwise artificially inflated reporting, nor can they be dismissed due to the huge number of COVID vaccines administered. There are several reasons why, but the simplest one is this: the safety signal analysis does not depend on the number of reports, but whether or not some AEs are reported at a higher rate for these vaccines than for other non-COVID vaccines. Other reasons are discussed in the full post below. In August, 2022, the CDC told the Epoch Times that the results of their safety signal analysis “were generally consistent with EB [Empirical Bayesian] data mining [conducted by the FDA], revealing no additional unexpected safety signals.” So either the FDA's data mining was consistent with the CDC's method—meaning they “generally” found the same large number of highly alarming safety signals—or the signals they did find were expected. Or they were lying. We may never know because the FDA has refused to release their data mining results. INTRODUCTION Finally! Zachary Stieber at the Epoch Times managed to get the CDC to release the results of its VAERS safety signal monitoring for COVID-19 vaccines, and they paint a very alarming picture (see his reporting and the data files here, or if that is behind a paywall then here). The analyses cover VAERS reports for mRNA COVID vaccines from the period from the vaccine rollout on December 14, 2020 through to the end of July, 2022. The CDC admitted to only having started its safety signal analysis on March 25, 2022 (coincidentally 3 days after a lawyer at Children's Health Defense wrote to them reminding them about our FOIA request for it). [UPDATE: T Coddington left a link in comments to a website where he made the data in the Excel files more accessible.] Like me, you might be wondering why the CDC waited over 15 months before doing its first safety signal analysis of VAERS, despite having said in a document posted to its website that it would begin in early 2021—especially since VAERS is touted as our early warning vaccine safety system. You might also wonder how they could insist all the while that the COVID-19 vaccines are being subjected to the most rigorous safety monitoring the world has ever known. I'll come back to that later. First I'm going to give a little background information on the analysis they did (which you can skip if you're up to speed) and then describe what they found. BACKGROUND ON SAFETY SIGNAL ANALYSIS Back in June 2022, the CDC replied to a Freedom of Information Act (FOIA) request for the safety signal monitoring of the Vaccine Adverse Events Reporting System (VAERS)—the one it had said it was going to do weekly beginning in early 2021. Their response was: we never did it. Then a little later they said they had been doing it from early on. But by August, 2022, they had finally gotten their story straight, saying that they actually did do it, but only from March 25, 2022 through end of July. The analysis they were supposed to do uses what's called proportional reporting ratios (PRRs). This is a type of disproportionality analysis commonly used in pharmacovigilance (meaning the monitoring of adverse events after drugs/vaccines go to market). The basic idea of disproportionality analysis is to take a new drug and compare it to one or more existing drugs generally considered safe. We look for disproportionality in the number of adverse events (AEs) reported for a specific AE out of the total number of AEs reported (since we generally don't know how many people take a given drug). We then compare to existing drugs considered safe to see if there is a higher proportion of particular adverse events reported for the new drug compared to existing ones. (In this case they are looking at vaccines, but they still use PRR even though they generally have a much better sense of how many vaccines were administered.)
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