Podcasts about Ichikawa

Fixation on Histology Blog: Enhancing Organoid Research with Histogel-Based Embedding Techniques Based on an Article By: Havnar, C., Holokai, L., Ichikawa, R., Chen, W., Scherl, A., & Shamir, E. R. (2024) Click to read this post.

EPISODE #446-- We return from Spring Break and mark the end of Black History Month with a journey back into our BS. That's right, we're talking a Yukio Mishima adaptation from the Golden Age of Japanese Cinema. Today we're rapping about Kon Ichikawa's CONFLAGRATION (1958), a beautiful look into post-War masculinity, obsession, disability, and religion. Good episode of a great movie. We also talk about WALLACE & GROMIT: VENGEANCE MOST FOWL (2025), RUNAWAY JURY (RIP Gene Hackman), THE TERMINATOR, HBO's THE PITT, Amazon's REACHER, and another Ichikawa banger, FIRES ON THE PLAIN. Good stuff. Join the cause at Patreon.com/Quality. Follow the us on on Bluesky at kislingconnection and cruzflores, on Instagram @kislingwhatsit, and on Tiktok @kislingkino. You can watch Cruz and show favorite Alexis Simpson on You Tube in "They Live Together." Thanks to our artists Julius Tanag (http://www.juliustanag.com) and Sef Joosten (http://spexdoodles.tumblr.com). The theme music is "Eine Kleine Sheissemusik" by Drew Alexander. Also, I've got a newsletter, so maybe go check that one out, too. Listen to DRACULA: A RADIO PLAY on Apple Podcasts, at dracularadio.podbean.com, and at the Long Beach Playhouse at https://lbplayhouse.org/show/dracula And, as always, Support your local unions! UAW, SAG-AFTRA, and WGA strong and please leave us a review on iTunes or whatever podcatcher you listened to us on!

20250404 - TKS - Mandel, Ichikawa, Huckabee by That KEVIN Show

EPISODE #445-- Once more into the breech for Black History Month. Today Cruz and James attempt to understand the impressionistic, indie cult horror classic, GANJA & HESS from 1973.  We also mourn the passing of Gene Hackman, talking about THE FRENCH CONNECTION (1971), as well as Kon Ichikawa's THE BURMESE HARP (Cruz has been on an Ichikawa kick-- we can't blame him). This is also our last film fro Black History Month, so we hope we did okay by the films, if nothing else. Join the cause at Patreon.com/Quality. Follow the us on on Bluesky at kislingconnection and cruzflores, on Instagram @kislingwhatsit, and on Tiktok @kislingkino. You can watch Cruz and show favorite Alexis Simpson on You Tube in "They Live Together." Thanks to our artists Julius Tanag (http://www.juliustanag.com) and Sef Joosten (http://spexdoodles.tumblr.com). The theme music is "Eine Kleine Sheissemusik" by Drew Alexander. Also, I've got a newsletter, so maybe go check that one out, too. Listen to DRACULA: A RADIO PLAY on Apple Podcasts, at dracularadio.podbean.com, and at the Long Beach Playhouse at https://lbplayhouse.org/show/dracula And, as always, Support your local unions! UAW, SAG-AFTRA, and WGA strong and please leave us a review on iTunes or whatever podcatcher you listened to us on!

Barrier Free Japan found a copy of ‘Hunchback' by Saou Ichikawa in the Osaka Umeda branch of Kinokuniya. I have been looking forward to reading this. Saou Ichikawa's ‘Hunchback' won the Akutagawa Prize in 2023. I would love to meet Saou Ichikawa. As people with disabilities we are not meant to use terms like ‘inspires', but as a fellow person with disabilities, she 'inspires' me to write fiction about having a disability in Japan - Ichikawa has congenital myopathy. ‘Hunchback' (Amazon JP): https://www.amazon.co.jp/-/en/Saou-Ichikawa/dp/0241700787/ref=sr_1_1?crid=YWLMGXWX9HX0&dib=eyJ2IjoiMSJ9.tviLY6Hihc9Wld73kSNFDNgIMyu95jzmtY1FHVvoFbo.O-ev19sX2ziT9J5aBh6OU0KTipw5EKycw-KkJEItoZw&dib_tag=se&keywords=hunchback+saou+ichikawa&qid=1741701309&sprefix=%2Caps%2C187&sr=8-1

In this episode, I sit down with love attraction coach Shannon Ichikawa to explore the journey of finding lasting love at different life stages. We discuss how dating in your 30s, 40s, 50s, and beyond differs, along with the unique challenges faced by widows, divorced women, and those who have never been married. Shannon shares powerful insights on overcoming "love blocks," the role of self-love in attracting the right partner, and practical strategies for making meaningful connections. Whether you're re-entering the dating scene or looking to deepen your understanding of love attraction, this conversation will leave you feeling inspired and empowered to open your heart to new possibilities.   My NEW BOOK 'The Sprinkle Effect' is now available HEREJoin Debbie's free Maybe I Can Facebook Community HERE

The Flagship Podcast returns this week with a packed show covering a ton of news and notes across the world of wrestling, including news that WWE's Lee Fitting was dismissed from ESPN due to misconduct allegations, WWE's disappointing Saturday Night's Main Event rating, NJPW Strong Style Evolved, the retirement of Stalker Ichikawa, a preview of ROH Final Battle 2024 & more!WWE's Lee Fitting was dismissed from ESPN due to misconduct allegations & Janel Grant's reps responded.WWE's Saturday Night's Main Event had a disappointing rating & more importantly, some patented Legentil Activity.NJPW Strong Style Evolved reviewDragongate Final Gate 2024 + Stalker Ichikawa RetirementROH Final Battle 2024 Preview& more!Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The Flagship Podcast returns this week with a packed show covering a ton of news and notes across the world of wrestling, including news that WWE's Lee Fitting was dismissed from ESPN due to misconduct allegations, WWE's disappointing Saturday Night's Main Event rating, NJPW Strong Style Evolved, the retirement of Stalker Ichikawa, a preview of ROH Final Battle 2024 & more!WWE's Lee Fitting was dismissed from ESPN due to misconduct allegations & Janel Grant's reps responded.WWE's Saturday Night's Main Event had a disappointing rating & more importantly, some patented Legentil Activity.NJPW Strong Style Evolved reviewDragongate Final Gate 2024 + Stalker Ichikawa RetirementROH Final Battle 2024 Preview& more!Support this podcast at — https://redcircle.com/voices-of-wrestling-flagship/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Welcome back to Open The Voice Gate! Case (https://twitter.com/_inyourcase) and Mike (https://twitter.com/fujiiheya) are back with an update on the comings and goings of Dragongate.It's a big Open The Voice Gate this week as Case and Mike are back to talk Dragongate, The Final Gate, and Konomama Ichikawa's retirement. They lead off with the Shimizu situation, GLEAT's PR and Subscription strategy. Then it's time to talk The Final Gate, the YAMATO vs Dragon Dia Double Dream and Brave Gate matches, and the rest of Dragongate's final “big show of the year. After that, Case and Mike review today's Korakuen with Konomama Ichikawa vs Hiroshi Tanahashi, a 3 way 6 man tag and a lot of fun from Tokyo!Our podcast provider, Red Circle, offers the listeners the option to sponsor the show. Click on “Sponsor This Podcaster” at https://redcircle.com/shows/open-the-voice-gate and you can donate a single time, or set up a monthly donation to Open The Voice Gate!Please Rate and Review Open The Voice Gate on the podcast platform of your choice and follow us on twitter at https://twitter.com/openvoicegate.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

Welcome back to Open The Voice Gate! Case (https://twitter.com/_inyourcase) and Mike (https://twitter.com/fujiiheya) are back with an update on the comings and goings of Dragongate.Mike is back with a bit of a Voice Gate update on his lunch break! He discusses the Shimizu suspension, what is known, where things are, and what he expects to come from this. After that, he talks about the Final Gate card changes, the full card for 12/17's Ichikawa Retirement show and spends some time laying the argument on why Hollywood Stalker Ichikawa was the greatest comedy wrestler of all time.Our podcast provider, Red Circle, offers the listeners the option to sponsor the show. Click on “Sponsor This Podcaster” at https://redcircle.com/shows/open-the-voice-gate and you can donate a single time, or set up a monthly donation to Open The Voice Gate!Please Rate and Review Open The Voice Gate on the podcast platform of your choice and follow us on twitter at https://twitter.com/openvoicegate.Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

The woke agenda is being pushed into every aspect of society. Ridiculous programs are allowing criminals to essentially pick the gender of prison they want to go to. Male rapists and sex offenders can simply identify as a woman and be placed in a women's prison while the women inmates are being raped, beaten and have no privacy as they are placed in cells with men. Amie Ichikawa, formerly a woman inmate in California's penal system exposes the corruption from inside the walls and explains step by step what women prisoners are enduring in today's ‘clown world.'Follow Amie: https://www.womaniiwoman.org/----------------------------------SPONSORS FOR THIS VIDEO❤️ Cardio Miracle - Boost your energy, help support your immune system, and improve your mental clarity-plus use promo code GRIT and save 10% on your order https://cardiomiracle.myshopify.com/discount/GRIT

This week you get two episodes, apologies on this late upload! Short version, had some personal stuff pop up but we got it handled! On to the anime, Kaiju number 8! We follow mainly Hibino, Kafka, a 32 year old man who always wanted to join the Defense Force but never passed. Also, another major character is his trainee/partner from the cleaning job named Ichikawa, Reno. We follow them through trying to join the force while also hiding a major secret, that Kafka is a kaiju himself! Next episode we will be reviewing another recent one, Solo Leveling! Want to join us live? Head over to twitch.tv/crazyjam where we live record each episode Wednesday night at 8:30 pm EST! If you want to recommend an anime to us, please use the following linktree to see our “recommend us an anime!” page and also every other way to interact with us! https://linktr.ee/xAnimeAnonymousx Ratings: Artsy: 8/10 Cj: 7/10

This week, we are over the moon to share with you our very special guest: LEAH WILLIAMS! The iconic writer of X-Factor, Power Girl, and next week's Gotham City Sirens sat down with us to share one of her all time favorites: LAND OF THE LUSTROUS by Haruko Ichikawa! It's a genre-defying epic that is part magical girl, part coming-of-age, part body horror, and all heart. it has this expansive and ambitious worldbuilding, with a mythose that sucks you in and exponentially amps up the tension.  

Talking about chapter 17 to 58 in this episode! Next week, we'll be catching up to the rest of the series and talking about where the story is currently. 

Irene o Irene Saki, nació en Japón, concretamente en Ichikawa de donde también es su madre. Allí pasó los primeros años de su vida hasta que, llegada la adolescencia, su familia se trasladó a la capital aragonesa, lugar natal de su padre. Desde entonces y de manera natural, Irene ha vivido entre estos dos mundos tan dispares, entendiendo e interiorizando de forma natural dos culturas totalmente diferentes. Y es por ello que es sin duda una de las mejores personas para acompañarnos en llevar a cabo una verdadera inmersión en el país nipón. No sólo nos ayudará con el idioma, a leer el jeroglífico que supone el plano del metro de Tokio o saber qué te estás llevando a la boca, sino a entender el choque cultural tan tremendo al que nos vamos a enfrentar. Además, Irene también es una amante de la Naturaleza y de las actividades al aire y por eso con ella no sólo recorreremos el Japón más icónico, sino también esos rincones de naturaleza alejados de turismo. La encontraremos sumergiéndonos en el Japón más rural y salvaje pero también será nuestro refugio en las grandes ciudades adentrándonos en bellos jardines o bosques de bambú. Y lo haremos de forma activa, sin palizas, pero sí en movimiento, con caminatas fáciles de un día, paseos urbanos en bici o rutas de cicloturismo asequibles para todas y con la facilidad de disponer de bicicletas eléctricas. Una no se puede ir de Japón sin experimentar ese Pulchrum es Sacrum (lo bello es sagrado) y es que el culto a la belleza de la naturaleza es pieza clave para entender el país nipón. Además para asegurarnos de que sí o sí lo vas a experimentar nos vamos en dos momentos clave: La Primavera y el Otoño. Pero no te cuento más, dale al play y que te lo cuente Irene, tu guía para visitar Japón con Hacia lo Salvaje. Más información en: http://hacialosalvaje.net/

Watch now | A discussion with Amie Ichikawa, incarcerated women's rights advocate. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit allenwest.substack.com/subscribe

How the f are their MEN in WOMEN'S prisons!??! In this episode, we sit down with Amie Ichikawa about her organization Woman II Woman, California Women's Prisons, and Keeping Prisons Single Sex. HONORABLE MENTIONS FOR THIS EPISODE: Mel @thatsfunnymel https://linktr.ee/ThatsFunnyMel K @authenticTERF linktr.ee/k_carnelian AMY ICHIKAWA @ichinita310 linktr.ee/ichix310 https://www.womaniiwoman.org/ @womaniiwomaninc https://linktr.ee/womaniiwoman https://iwforum.org/ @IWF DISHONORABLE MENTIONS: Ellen/Elliott Page at the JUNO Awards https://youtu.be/y_gfIxmaMLw?si=PegvUNixmc7l-e4L --- Send in a voice message: https://podcasters.spotify.com/pod/show/itismaam/message Support this podcast: https://podcasters.spotify.com/pod/show/itismaam/support

How the f are their MEN in WOMEN'S prisons!??! In this episode, we sit down with Amie Ichikawa about her organization Woman II Woman, California Women's Prisons, and Keeping Prisons Single Sex. HONORABLE MENTIONS FOR THIS EPISODE: Mel @thatsfunnymel https://linktr.ee/ThatsFunnyMel K @authenticTERF linktr.ee/k_carnelian AMY ICHIKAWA @ichinita310 linktr.ee/ichix310 https://www.womaniiwoman.org/ @womaniiwomaninc https://linktr.ee/womaniiwoman https://iwforum.org/ @IWF DISHONORABLE MENTIONS: Ellen/Elliott Page at the JUNO Awards https://youtu.be/y_gfIxmaMLw?si=PegvUNixmc7l-e4L --- Send in a voice message: https://podcasters.spotify.com/pod/show/itismaam/message Support this podcast: https://podcasters.spotify.com/pod/show/itismaam/support

Etes-vous satisfait du niveau d'investigation des déviations sur votre site ? Si c'est non, sachez que c'est un mal récurent sur les sites.  On a évoqué de multiples raisons ces dernières semaines (manque de temps, processus trop compliqué, rôle et responsabilité, pas de pilotage..) et aujourd'hui on va parler de la plus évidente de toute : La méthode d'investigation. Quand on n'en a pas, ça prend tout de suite beaucoup plus de temps de commencer et les investigations ne sont pas homogènes. Quand on a que des outils on n'obtient pas une histoire cohérente (5m/Ichikawa) ou on se focalise sur une seule partie du problème (5M) et dans tous les cas le niveau de l'investigation est difficile à adapter au niveau de criticité. Dans l'épisode d'aujourd'hui on vous parle d'une technique qui va fonctionner dans 80% des cas, qui raconte l'histoire et qui va vous donner des causes primaires suffisantes pour mettre des CAPA intéressantes si on veut s'arrêter là. Je vous laisse découvrir ça. Mes plus plates excuses pour mon son à faire saigner les oreilles les plus endurcies... un conflit de pilotes entre mon casque et ma platine m'a empêché d'utiliser mon micro... je suis dégoûté mais c'est comme ça. On réenregistrera peut-être plus tard. Bonne écoute quand même ! Retrouver notre site : https://academiedelaqualiteefficace.lpages.co/home/ C'est marqué dans les BPF : https://www.podcastics.com/podcast/4330/link/ La chaîne Youtube pour les lives et les redifs : https://www.youtube.com/channel/UC3_l-vgXrXIucvv99bYdYrw  

Megyn Kelly is joined by Jesse Kelly, host of TheFirst TV's "I'm Right,” to discuss the slimy corruption exposed in the Fani Willis story, Terrance Bradley possibly telling more lies on the stand about his relationship with Nathan Wade, “crooked politics” in small towns, details about a potential start date for the Trump Florida classified documents case, Jack Smith pushing for trials before the election, MSNBC's Rachel Maddow predicting Trump will try to stay president “for life,” whether people like her really believe what she says on-air about Trump, how Trump is really a moderate politically, Democrats finally beginning to wake up to the danger of illegal immigration in America, the White House refusing to discuss the details about the illegal migrant charged with murdering Laken Riley, and more. Then Kelsey Bolar and Amie Ichikawa, of the Independent Women's Forum, join to discuss the new documentary "Cruel & Unusual Punishment: The Male Takeover of Women's Prisons," about the danger of biological males in women's prisons, Amie's personal experience, the issues in California, and more.Kelly- https://www.jessekellyshow.com/Ichikawa & Bolar- https://www.iwf.org/ Follow The Megyn Kelly Show on all social platforms: YouTube: https://www.youtube.com/MegynKellyTwitter: http://Twitter.com/MegynKellyShowInstagram: http://Instagram.com/MegynKellyShowFacebook: http://Facebook.com/MegynKellyShow Find out more information at: https://www.devilmaycaremedia.com/megynkellyshow

On this week of This is a Woman, Host Sophia Lorey sits down with Amie Ichiwaka to discuss men (who are "identifying" as women) are being put in women only prisons. Amie Ichiwaka is the Founder, Executive Director, of Woman ii Woman, a community of previously incarcerated women providing resources, education, and support services for system-impacted women. They stand in solidarity with our sisters, being a voice for the voiceless and ensuring them that they are not forgotten.Tune in to learn about...- Are men really in women only prisons? - The stats of what type of incarcerated men are going into women only prisons. - Tax payer $$$ going to trans-surgeries in prison.- The erasure of women from sports, to language, prisons.You can learn more about this as womaniiwoman.orgor follow along on their instagram @womaniiwomaninc

It's Review Season, and in 13th place, we've positioned several of Japan's most renowned creative houses, with both film adaptations of ‘The Inugami Clan'. Author Seishi Yokomizo continues to haunt japanese mystery fiction, with spinoffs and adaptations of his leading detective, Kosuke Kindaichi, continuing production over forty years after his passing. Kon Ichikawa was perhaps more prolific, even if his comparisons to other contemporaneous Japanese directors are less universal.

Researchers define a protocol for narrow nanoneedle fabrication and high-resolution imaging of living cells using AFM  Transcript of this podcastHello and welcome to the NanoLSI podcast. Thank you for joining us today. In this episode we feature the latest research by Takehiko Ichikawa and Takeshi Fukuma at the Kanazawa University NanoLSI.The research described in this podcast was published in STAR Protocols in September 2023 Kanazawa University NanoLSI websitehttps://nanolsi.kanazawa-u.ac.jp/en/Researchers define a protocol for narrow nanoneedle fabrication and high-resolution imaging of living cells using AFM Researchers at Kanazawa University report in STAR Protocols procedural details and tips for nanoendoscopy-AFM, for capturing images of nanoscale structures inside living cells. Images of nanoscale structures inside living cells are in increasing demand for the insights into cellular structure and function they can reveal. So far, the tools for capturing such images have been limited in various ways, but researchers led by Takeshi Fukuma and Takehiko Ichikawa at Kanazawa University have now devised and reported a full protocol for using atomic force microscopy (AFM) to image inside living cells. AFM was first developed in the 1980s and uses the changes in the forces between a sample surface and a nanoscale tip attached to a cantilever to “feel” surfaces and produce images of the topography with nanoscale resolution. The technique has grown increasingly sophisticated for extracting information about samples and at speeds sufficient for the tool to capture moving images of dynamics at the nanoscale. However, so far, it has been limited to surfaces. Other techniques exist that can provide a view of the inside of a cell but with limitations. For instance, there is electron microscopy, which is capable of resolving details at the nanoscale and smaller, but the required operating conditions are not compatible with living cells. Alternatively, fluorescence microscopy is regularly used on living cells, but while fluorescence techniques exist to increase the resolution, there are practical challenges that inhibit fluorescence imaging at the nanoscale. AFM suffers from neither limitation and by embellishing the tool with a nanoneedle to penetrate cells, Fukuma, Ichikawa and their collaborators have recently demonstrated the capability to image inside cells at the nanoscale, which they describe as nanoendoscopy-AFM.So how does it work?In their protocol, the researchers break down the method for nanoendoscopy-AFM into 4 stages. The first few steps involve cell preparation and staining with a fluorescent dye and checking the fluorescence, which is used to identify the imaging area quickly. Next is the fabrication of the nanoneedles themselves, for which there are two options – either etching away a nanoneedle structure with a focused ion beam or building one up with electron beam deposition. Then comes the nanoendoscopy stage itself, and in the report, the researchers describe the approach for both 2D  and 3D nanoendoscopy. There are even details outlined to describe the best way to clean up after the nanoendoscopy images are captured before finally outlining the data processing needed to visualize the measured data. The method is replete with tips for successfully accomplishing each stage, as well as a guide for troubleshooting when things are not quite working out. This technique should be suitable for the observation of intact intracellular structures, including mitochondria, focal adhesions, endoplasmic reticulum, lysosomes, Golgi apparatus, organelle connections, and liquid-liquid phase-separated structures. They conclude, “This protocol can NanoLSI Podcast website

On this week's episode of TheFallenState TV, host Jesse Lee Peterson is joined by Amie Ichikawa—She is a former inmate, and executive director and founder of Woman II Woman, a nonprofit organization dedicated to supporting formerly incarcerated women through resources, education, and vital support services. In this heartfelt conversation, Jesse and Amie discuss her personal journey, the challenges of reintegration into society after incarceration, and the critical role organizations like Woman II Woman play in helping women rebuild their lives. Prepare to be inspired as they explore themes of redemption, resilience, and the importance of extending a helping hand to those seeking a fresh start. Don't miss this touching episode as Jesse and Amie shed light on the path to recovery, healing, and hope for formerly incarcerated women.

On this week's episode of TheFallenState TV, host Jesse Lee Peterson is joined by Amie Ichikawa—She is a former inmate, and executive director and founder of Woman II Woman, a nonprofit organization dedicated to supporting formerly incarcerated women through resources, education, and vital support services. In this heartfelt conversation, Jesse and Amie discuss her personal journey, the challenges of reintegration into society after incarceration, and the critical role organizations like Woman II Woman play in helping women rebuild their lives. Prepare to be inspired as they explore themes of redemption, resilience, and the importance of extending a helping hand to those seeking a fresh start. Don't miss this touching episode as Jesse and Amie shed light on the path to recovery, healing, and hope for formerly incarcerated women.

Amie was incarcerated for 5 years at the Central California Women's Facility in Chowchilla. She is one of the founding members of "Woman II Woman", an organization empowering incarcerated women. We talk about biological men being placed in women's prisons, who profits off of inmates and how, and what you can do to help. This is a very important episode - please stream & share it.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.08.03.551778v1?rss=1 Authors: Ohno, Y., Nakamura, T., Iwasaki, T., Katsuyama, A., Ichikawa, S., Kihara, A. Abstract: Protein-bound ceramides, specialized ceramides covalently bound to corneocyte surface proteins, are essential for skin permeability barrier function. However, their exact structure and target amino acid residues are unknown. Here, we found that epoxy-enone (EE) ceramides, precursors of protein-bound ceramides, as well as their synthetic analog, formed stable conjugates only with Cys among nucleophilic amino acids. NMR spectroscopy revealed that the beta-carbon of the enone was attached by the thiol group of Cys via a Michael addition reaction. We confirmed the presence of Cys-bound EE ceramides in mouse epidermis by mass spectrometry analysis of protease-digested epidermis samples. EE-ceramides were reversibly released from protein-bound ceramides via sulfoxide elimination. We found that protein-bound ceramides with reversible release properties accounted for approximately 60% of total protein-bound ceramides, indicating that Cys-bound EE ceramides are the predominant protein-bound ceramides. Our findings provide clues to the molecular mechanism of skin barrier formation by protein-bound ceramides. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

We discuss two films adapted from Seishi Yokomizo's 'The Inugami Curse', both made by Kon Ichikawa, both starring Kōji Ishizaka as Kosuke Kindaichi. Originally adapted in 1976, then remade in 2006, the film follows the inheritance dispute of the powerful Inugami pharmaceutical family. The patriarch passes, and his various wives and their children have their claim to wealth upended by the return of Sukekiyo, a grandson scarred unrecognisable in the second world war. The death of a legal representative draws the attention of the enigmatic Kosuke Kindaichi, who finds both allies and enemies as he tries to prevent the police from imprisoning the wrong person. What changed between the two versions of the film, and how does this Japanese classic hold up?

Sao Ichikawa, the winner of the Akutagawa Prize, is a 43-year-old resident of Kanagawa Prefecture. She was diagnosed with congenital myopathy, a muscle disease, one of the most intractable diseases, when she was 10 years old, began using a ventilator at the age of 14, uses an electric wheelchair for transportation, and writes using a tablet device. Episode Notes: https://barrierfreejapan.com/2023/07/19/sao-ichikawa-woman-with-congenital-myopathy-wins-japans-akutagawa-prize/ https://barrierfreejapan.com/2023/07/20/i-wrote-this-with-the-mind-that-there-are-not-many-authors-like-me-says-sao-ichikawa-woman-with-a-disability-on-winning-the-akutagawa-prize/

Amie Ichikawa is an ex-convict who now works to help women in and out of prison. In this calmvo we talk about the situation in California, wherein male criminals are given a free pass to be locked up with women. https://www.womaniiwoman.org https://linktr.ee/ichix310 Support this channel:  https://www.paypal.me/benjaminboyce https://cash.app/$benjaminaboyce https://www.buymeacoffee.com/benjaminaboyce --- Send in a voice message: https://podcasters.spotify.com/pod/show/calmversations/message Support this podcast: https://podcasters.spotify.com/pod/show/calmversations/support

Dans ce premier épisode de Plan Tatamix, Corentin vous propose de plonger les deux oreilles en avant dans la filmographie de Kon Ichikawa.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.26.534053v1?rss=1 Authors: Itahashi, T., Yamashita, A., Takahara, Y., Yahata, N., Aoki, Y. Y., Fujino, J., Yoshihara, Y., Nakamura, M., Aoki, R., Ohta, H., Sakai, Y., Takamura, M., Ichikawa, N., Okada, G., Okada, N., Kasai, K., Tanaka, S. C., Imamizu, H., Kato, N., Okamoto, Y., Takahashi, H., Kawato, M., Yamashita, O., Hashimoto, R.-i. Abstract: Autism spectrum disorder (ASD) is a lifelong condition, and its underlying biological mechanisms remain elusive. The complexity of various factors, including inter-site and development-related differences, makes it challenging to develop generalizable neuroimaging-based biomarkers for ASD. This study used a large-scale, multi-site dataset of 730 Japanese adults to develop a generalizable neuromarker for ASD across independent sites (U.S., Belgium, and Japan) and different developmental stages (children and adolescents). Our adult ASD neuromarker achieved successful generalization for the US and Belgium adults (area under the curve [AUC] = 0.70) and Japanese adults (AUC = 0.81). The neuromarker demonstrated significant generalization for children (AUC = 0.66) and adolescents (AUC = 0.71; all P less than 0.05, family-wise-error corrected). We identified 141 functional connections (FCs) important for discriminating individuals with ASD from TDCs. These FCs largely centered on social brain regions such as the amygdala, hippocampus, dorsomedial and ventromedial prefrontal cortices, and temporal cortices. Finally, we mapped schizophrenia (SCZ) and major depressive disorder (MDD) onto the biological axis defined by the neuromarker and explored the biological continuity of ASD with SCZ and MDD. We observed that SCZ, but not MDD, was located proximate to ASD on the biological dimension defined by the ASD neuromarker. The successful generalization in multifarious datasets and the observed relations of ASD with SCZ on the biological dimensions provide new insights for a deeper understanding of ASD. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

It's been a busy month! Welcome to Edition 82 wherein the WLRN Collective, along with Amie Ichikawa, joey brite, Thistle Pettersen, and Sekhmet SheOwl, explores the story and implications of the ongoing "Dana Rivers" #DanaRiversisaMan Case in California. It is a gruesome subject that is paired with aurora linnea's chilling written piece about the murders committed by trans-identified individuals over the years. https://wlrnmedia.com/2023/02/02/femicide-unmentionable-crimes/ On a more cheerful note, WLRN is starting a new merch line featuring the beautiful artwork and design of Margaret Vaek. Margaret greets the listener in this February's show describing the WLRN logo she lovingly designed. To see our new merch line, click here: https://wlrnmedia.com/merch/ Of note, Margaret also designed the front cover for this month's podcast. It represents Charlotte Reed, Patricia Wright and Benny Diambu-Wright, along with the colors of the suffragist flag (USA), as the fight for women's rights continues. In this month's edition, Emily Faye delivers WLRN's world news segment updating the listener on April Morrow's case involving a man who crushed her hand at a Women's Speak Out event last Fall, amongst other stories. After the world news, hear the song 'Women's Prison' by Loretta Lynn before jumping into a conversation Thistle had with Amie Ichikawa and joey brite about the David Warfield case. This excerpt is from the livestreamed conversation that happened last month with a live interactive audience. Click the "Live" tab on our YouTube channel to find the entire unedited livestream recording in our archive. Finally, Sekhmet SheOwl rounds off the hour with her punchy commentary on the subject in her usual to-the-point fashion that hits the nail on the proverbial head of patriarchy. Thank you, Sekhmet, for your years of service to our collective and for broaching this gruesome topic with precision. The logic you present is crystal clear. and your anger is wielded like a knife. This brings us to the subject of March's show which will focus on women's self-defense. As always, thank you, dear listeners, for supporting feminist community-powered media, WLRN. Let's make it through 2023 together in our worldwide women's network and community. In solidarity! Again, that new merch page is accessible here: https://wlrnmedia.com/merch/ We hope you enjoy browsing our new store!

There's a new California law that everyone should know about. We bring on former inmate Amie Ichikawa for an in-depth discussion.

Nick meets Georgie Ichikawa. Georgie was born 1982 in Tokyo,  and moved to UK when he was 16.He later graduated from University of Arts London ( London College of Fashion ) MA Fashion Design Technology with scholarship. At age of 25 he became head designer for PUMA x Alexander McQueen .In 2018 he was a founding member to start MR GAY JAPAN in which he became chair person for the organization for activism for the LGBTQ community in Japan. He is currently working at PUMA JAPAN as Head of Creative and Design.

Tariq and Jim have a talk about slapstick comedy in wrestling. We talk about our favorite workers in this genre and promotions that you should absolutely check out. This week's match features one of the funniest slapstick comedians in wrestling that most North American fans have no idea about. This week's match is over in 23 seconds but don't worry, Stalker gets an immediate re-match that unfortunately also doesn't work out in his favor. Both matches were outstanding from a comedy perspective. --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/sixmantagpodcast/support

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.08.29.505635v1?rss=1 Authors: Han, L. K., Dinga, R., Leenings, R., Hahn, T., Cole, J., Aftanas, L., Amod, A., Besteher, B., Colle, R., Corruble, E., Couvy-Duchesne, B., Danilenko, K., Fuentes-Claramonte, P., Saffet Gonul, A., Gotlib, I., Goya-Maldonado, R., Groenewold, N., Hamilton, P., Ichikawa, N., Ipser, J., Itai, E., Koopowitz, S.-M., Li, M., Okada, G., Okamoto, Y., Olga, C., Osipov, E., Penninx, B., Pomarol-Clotet, E., Rogriguez-Cano, E., Sacchet, M., Shinzato, H., Sim, K., Stein, D., Uyar-Demir, A., Veltman, D., Schmaal, L. Abstract: Background: Several studies have evaluated whether depressed persons have older appearing brains than their nondepressed peers. However, the estimated neuroimaging derived brain age gap has varied from study to study, likely driven by differences in training and testing sample (size), age range, and used modality/features. To validate our previously developed ENIGMA brain age model and the identified brain age gap, we aim to replicate the presence and effect size estimate previously found in the largest study in depression to date (N=2,126 controls & N=2,675 cases; +1.08 years [SE 0.22], Cohen's d=0.14, 95% CI: 0.08 to 0.20), in independent cohorts that were not part of the original study. Methods: A previously trained brain age model (www.photon-ai.com/enigma_brainage) based on 77 FreeSurfer brain regions of interest was used to obtain unbiased brain age predictions in 751 controls and 766 persons with depression (18-75 years) from 13 new cohorts collected from 20 different scanners. Results: Our ENIGMA MDD brain age model generalized reasonably well to controls from the new cohorts (predicted age vs. age: r = 0.73, R2=0.47, MAE=7.50 years), although the performance varied from cohort to cohort. In these new cohorts, on average, depressed persons showed a significantly higher brain age gap of +1 year (SE 0.35) (Cohen's d=0.15, 95% CI: 0.05 to 0.25) compared with controls, highly similar to our previous finding. Conclusions: This study further validates our previously developed ENIGMA brain age algorithm. Importantly, we replicated the brain age gap in depression with a comparable effect size. Thus, two large-scale independent mega-analyses across in total 32 cohorts and >3,400 patients and >2,800 controls worldwide show reliable but subtle effects of brain aging in adult depression. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

durée : 00:49:59 - Les Nuits de France Culture - Connaître le cinéma - Le cinéma japonais : "Feux dans la plaine" de Kon Ichikawa (1ère diffusion : 21/03/1964 France III Nationale)

In a small clear box, Etsuko Ichikawa keeps a small piece of vitrified glass that was given to her on a tour of the Hanford nuclear site. This vitrified glass encases radioactive material before it is disposed of through burial. As an artist trained in making glass, this object becomes something of a totem for Ichikawa, who turns her eye towards nuclear legacies,environmental degradation, and human impacts on the environment.Related Links: Etsuko Ichikawa's websiteBroken Poems of Fireflies exhibitEtsuko introduces the exhibitDo you have a special object that you hold close? Share it with us on Instagram. Tag @KUOW and use the hashtag: #bluesuitpod.Your feedback matters to us. Submit your comments and questions to www.kuow.org/feedback 

Jen has taken a break from the podcast, and today she joins as a guest to talk about it.  This episode is powered by Gordon FoodService, Charpiers Bakery, GoTab, and Maintain IQ --- Send in a voice message: https://anchor.fm/brandon-styll/message

Jack Straw Artist Etsuko Ichikawa has launched her new podcast Traveling Clouds, produced in part through the Jack Straw Artist Support Program. The first episode is about Tutu Pele, the goddess of volcanoes and fire and the creator of the Hawaiian islands. Learn more and subscribe to Traveling Clouds at anchor.fm/etsuko-ichikawa9. The post Etsuko Ichikawa – Traveling Clouds Podcast Episode 1 appeared first on Jack Straw Cultural Center.

To celebrate the start of season 2, we chat with real life Cobra Kai Karate; Justin Ichikawa of American Tang Soo Do.Justin shares what it was like growing up in the martial arts with his father (Dennis Ichikawa ) as his sensei. How his father started with Chuck Norris and eventually went on to own his own Karate school. Justin's journey as a martial artist is fascinating. Please enjoy!https://www.towestlakekarate.com/http://www.facebook.com/towestlakekarate/https://www.instagram.com/towestlake_karate/https://www.youtube.com/senseiichi

This episode of Big Blend Radio's 1st Friday "Toast to The Arts & Parks" Show features multimedia artist Etsuko Ichikawa who talks about her month-long Hawai'i Volcanoes National Park experience as the Fall 2021 National Parks Arts Foundation artist-in-residence. More about Etsuko's art and career: http://www.etsukoichikawa.com/More about the National Parks Arts Foundation: https://www.nationalparksartsfoundation.org/

This episode of Big Blend Radio's 1st Friday "Toast to The Arts & Parks" Show features multimedia artist Etsuko Ichikawa who talks about her month-long Hawai'i Volcanoes National Park experience as the Fall 2021 National Parks Arts Foundation artist-in-residence. More about Etsuko's art and career: http://www.etsukoichikawa.com/ More about the National Parks Arts Foundation: https://www.nationalparksartsfoundation.org/

Amie Ichikawa is one the founders of WomanIIWoman, a non-profit organization providing re-entry services, parole hearing prep, and advocacy for the safety and dignity of incarcerated women in California. She serves as an advocate for women in the Central California Women's Facility and the California Institution for Women, standing for justice for victims of State abuse. Amie shares her eye-opening experience being incarcerated for five years and re-integrating back into society after enduring incredible amounts of abuse and harassment by correctional officers. She discusses the cultural differences between men's and women's prisons, the numerous dangers of SB132 (also known as The Transgender Respect, Agency and Dignity Act), and how her coercion to get vaccinated in prison is emblematic of the current global situation. Amie encourages others to have one-on-one, intimate conversations about these issues not only for the sake of incarcerated women but also for the protection of women everywhere against impending erasure and further dehumanization. Donate to WomanIIWoman: https://www.paypal.com/paypalme/womaniiwoman Open letter to stop SB132: https://www.womaniiwoman.org/open-letter-stop-sb132 WomanIIWoman: https://www.womaniiwoman.org/ ➢➢➢ SUPPORT THE PODCAST | https://www.paypal.com/paypalme/whosebodyisit?locale.x=en_US 1:1 COACHING SOVEREIGN WOMEN | https://www.whosebodyisit.com/coaching-for-sovereign-women HYPNOSIS FOR HEALING & RADICAL CHANGE | https://www.whosebodyisit.com/hypnosis SHOP ACTIVIST STICKERS | https://www.whosebodyisit.com/shop INSTAGRAM | https://www.instagram.com/whosebodyisit/

Support the show! http://patreon.com/magicmics Visit our sponsor: http://www.coolstuffinc.com/ Check out the twitch channel: http://twitch.tv/magicmics Visit our subreddit: http://www.reddit.com/r/magicmics Follow us on Twitter: http://twitter.com/magicmicscast Like us on Facebook: http://facebook.com/magicmics Co-Sponsors: http://www.cardhoarder.com/ http://www.alteredsleeves.com/ (use code MAGICMICS ) http://www.cubeks.com/ AirDate - 10/7/2021 First Pick   Worlds Championship Roundup Ikawa Mistaken for Ichikawa: https://twitter.com/fireshoes/status/1443975790064963587 Fixed: https://magic.gg/news/insider-picks-for-magic-world-championship-xxvii Misspelled Hashtag: https://twitter.com/MagicEsports/status/1445071317242466306?s=20 https://cdn.discordapp.com/attachments/410942703623208960/894639258952958012/unknown.png Fixed: https://twitter.com/MagicEsports/status/1445079869155680259?s=20 Wrong Author: https://twitter.com/MagicEsports/status/1445161812530503683?s=20 https://twitter.com/nicknprince/status/1445176659988996096?s=20 https://twitter.com/ellieoftheveil/status/1445177643675045919?s=20 Decklists Posted Early: https://twitter.com/fireshoes/status/1445380154633728019 https://www.reddit.com/r/magicTCG/comments/q1xxvp/worlds_metagame_and_decklists_leaked/ https://twitter.com/MagicEsports/status/1445442979846520833 https://twitter.com/MTGMelee/status/1445432662508941314?s=20 https://twitter.com/crokeyz/status/1445458073187848192?t=828OrUXUk8jdS0ZoN-cV7A&s=19 Wrong Formats: https://twitter.com/yoman_5/status/1445442038376411136?s=20 Metagame: https://magic.gg/news/magic-world-championship-xxvii-metagame-breakdown   Gather the Townsfolk   APAC Promos Moved From Play Rewards to Buy-a-Box: https://cdn.discordapp.com/attachments/410942703623208960/893521222472728616/242387762_4381289955282486_1147765779787088359_n.jpg https://wpn.wizards.com/en/article/additional-apac-exclusive-return-store-play-promos-and-events   Pithing Needle Banned in Brawl: https://twitter.com/wizards_help/status/1443994094200623122?s=21   BDM's First Pitch: https://twitter.com/top8games/status/1445803157208985602?s=21   Standard: Through the Ages: https://magic.wizards.com/en/articles/archive/magic-online/standard-through-ages-2021-10-05   Extra Life: https://magic.wizards.com/en/articles/archive/news/join-wizards-coast-extra-life-2021-10-06   Desperate Ravings   Judge Academy 2022: https://judgeacademy.com/judge-academy-2022-announcements/ https://cdn.discordapp.com/attachments/410942703623208960/895023351444160542/image0.png   CFB Updates Judge Pay for MTG Vegas: https://judgeacademy.com/events/mtg-las-vegas/   More Legends Than Ever: https://twitter.com/sheepycutie/status/1445734836984074240?s=20 Twitch Leaked: https://www.videogameschronicle.com/news/the-entirety-of-twitch-has-reportedly-been-leaked/ https://www.theverge.com/2021/10/6/22712250/twitch-hack-leak-data-streamer-revenue-steam-competitor https://twitter.com/Twitch/status/1445770441176469512?s=20 https://twitter.com/twitch/status/1446033897234513920?s=21   GIVEAWAY & THANKS https://streamlabs.com/dashboard#/subscribers

Our Co-Host on the Podcast and her husband own a restaurant, and today they join the show with their partner Michael Kaplan to talk about their recent filming for Diners, Drive-in's, and Dives. We also just goof off and have some fun. Please go watch the video on our YouTube Channel. This episode sponsored by Complete Health Partners, Supersource, What Chef's Want, and Sitex. To Donate to the Tennessee Breast Cancer Coalition, Venmo- @nashvilleRR or visit www.tbcc.org --- Send in a voice message: https://anchor.fm/brandon-styll/message Support this podcast: https://anchor.fm/brandon-styll/support

Amie Ichikawa was formerly incarcerated in California. She recently founded the nonprofit organization Woman II Woman inc. This organization was originally created as a resource hub for reentry services but has become much more after California's SB132 “The Transgender Respect, Agency and Dignity Act” which has allowed gender self ID in prisons creating an unbelievable violation of human rights.

Morgana is out on vacation but she left the guys a reading list for some Yen Press books! We're checking out Yama Wayama's pleasant collection of high school slice-of-life stories, Captivated, by You! Also, Seamus spoils Land of the Lustrous volume 11 and dakazu talks about humans turned into plants with Fool Night!!! Save 20% off Manscaped products by using our discount code: MANGAMAC Send us emails! mangamachinations@gmail.com  Follow us on Twitter! @mangamacpodcast Check out our website! https://mangamachinations.com Check out our YouTube channel! https://www.youtube.com/mangamactv Check out our tumblr! http://mangamachinations.tumblr.com Join our Discord! https://discord.me/mangamac Buy us a Ko-fi! https://ko-fi.com/mangamac   Timestamps: 00:00:00 - Intro Song: “Are You Ready For Me Baby” by Funky Giraffe, Opening, Introductions 00:01:17 - Listener Mail: Good manga with bad endings 00:16:31 - Whatchu Been Reading: Transition Song: "Funkymania" by The Original Orchestra, *SPOILERS* Seamus and dakazu discuss all the literal changes to Phosphorite in Land of the Lustrous volume 11 00:34:17 - Fool Night follows a man crushed by poverty in a world without sunlight where humans are implanted with seeds to grow plants 00:40:04 - Next Episode Preview and Rundown: Triple Dip, We will read the beginning of three different Yen Press manga to pick our favorite, Including: Mieruko-chan by Tomoki Izumi, Eniale & Dewiela by Kamome Shirahama, and Uncle from Another World by Hotondoshindeiru 00:41:36 - MANSCAPED ad break 00:43:39 - Main Segment One Shot: Captivated, by You, Transition Song: “It's Over” by Generation Lost, we review Yama Wayama's collection of slice-of-life stories revolving around the eccentric Hayashi and the gloomy Nikaido 01:07:15 - Next Week's Topic: Mieruko-chan/Eniale & Dewiela/Uncle from Another World, Social Media Rundown, Sign Off Song: “Crazy for Your Love” by Orkas

I have recorded 175 episodes of Nashville Restaurant Radio in the past 16 months. I have had some pretty awesome co hosts on the show when we were doing the Music City Roundup. (Hey, it's coming back!!) Today I am going to introduce you to a new Co-Host, Jen Ichikawa. I like to look back on interviews and think about anything that could have made them better, and think some of our best shows were with Delia Jo Ramsey and Kelly Sutton. I wanted to bring some of that back on an every show basis, so Jen agreed to come on and give it a shot. (Our first interview airs this Friday with Jordan Williams) This episode is an introduction to my new Co-Host, please welcome her to the show! Brandon --- Send in a voice message: https://anchor.fm/brandon-styll/message Support this podcast: https://anchor.fm/brandon-styll/support

"Starring Sally J. Freedman as Herself," the appendix! Dedicated to all things Sally: a brief history of baton twirling, sex ed in the 1940s, child psychology, Howard Hughes' cantilevered bra design, everything you wanted to know about Creme de Cacao, and Esther Williams' dalliance with LSD. Esme and Anne from the Stuck in Stoneybrook podcast join Alison and Jody for Judy Blume deep cuts and chat about animal sex. We also read two wonderful listener letters (thank you Sherie and Dustin!). AND there's a bonus hidden track – keep listening for a Special Report on water bugs from a 7-year-old Blume Head, Lucy! It's a Judy Blume book club. Join us every week! PS: be sure to follow Blume Saloon social media for our next book announcement.

UKPラジオの第40回は、UK.PROJECTの歴史 vol.4！ 先月よりUK.PROJECTの歴史をテーマに、お届けしているUKPラジオ！ 今回はゲストにフリーライターの兵庫慎司さんをお迎えし、1990年代後半の音楽シーンとLibra recordsを振り返っていきます。 音楽を中心に演劇やお笑いなど、フリーライターとして幅広く活躍されている兵庫さん。 UK.PROJECTのアーティストのライブレポートはもちろん、夏に開催しているUK.PROJECTのフェスイベント「UKFC on the Road」のライブレポートも毎年書いていただいています。 UK.PROJECTが設立した1991年。同年、兵庫さんは株式会社ロッキング・オンに入社。 UK.PROJECTがレーベルとして波に乗りはじめ、多忙な日々を過ごしていた1990年代後半には、兵庫さんもロッキング・オン・ジャパンやBUZZなどの音楽雑誌で活躍！ その当時からUK.PROJECTに関する記事を書いていただいており、兵庫さんとUK.PROJECTは音楽シーンをともに駆け抜けてきた盟友でもあります。 CDもよく売れ、盛り上がっていた90年代後半。 UK.PROJECTはレーベルとして、兵庫さんは音楽雑誌の編集者として駆け抜けた当時の音楽シーンをお互いの視点から深掘りしていきます。 洋楽も邦楽も隔たりなく盛り上がり、ロックもダンスミュージックも流行り始めていた1999年頃。 演奏に打ち込みを取り入れるアーティストも増え始め、その先頭を走っていたのがPOLYSICSだと語る兵庫さん。 初ワンマンライブも観に行き、自身が担当していたロッキング・オンのライブイベントにもPOLYSICSを何度もブッキングするなど、当時からPOLYSICSをよく知る兵庫さんが感じていた、1999年頃の音楽シーンとPOLYSICSの印象とは？ 同じ頃の1999年5月には、UK.PROJECT内にLibra recordsが設立。 当時から、個性的なレーベルの集合体でありたいという思いがあったUK.PROJECT。 色々なアーティスト、プロデューサーがそれぞれの個性やカラーを大事にし、1組につき1レーベルを作ろうという考えのもと、それまではTV-FREAK RECORDSからリリースしていたYOUNG PUNCHを中心に設立されたのがLibra recordsでした。 そして、Libra recordsからGOING STEADYのリリースへ！ “大変なことになっている！お客さんがみんな泣いている！今度代々木公園で野外ライブやるから観に来て！！” と言われてGOING STEADYを観に行ったという兵庫さん。 かなり熱狂的なライブで今までにはない大きな衝撃を受けたと語る、GOING STEADY 野外ライブについても振り返っていきます。 パンクシーンも熱く盛り上がっていた当時、突如現れたGOING STEADYの影響で音楽雑誌界にも変化が！？ 音楽雑誌の中心にいた兵庫さんだからこそ語られるエピソードがたっぷりと登場します。 そして現在のコロナ禍における音楽シーンについても、番組ホスト・遠藤、兵庫さんが各々の視点で語り合います。 コロナ禍を逆手にとり、今だからこそできる表現方法によって多様化している配信ライブや楽しみ方などについても。 多くのライブを観ている兵庫さんが、アイデアに驚かされた配信ライブとは？ その他、UKPラジオだから聴くことのできるエピソードも続々と登場！ かつてはTHE STREET BEATS、GEENAのベースとして活動し、現在はPOTSHOTのベースであるICHIKAWAと同郷の兵庫さん。 同じ場所で青春時代を過ごした2人の思い出話や学生時代の話、当時の裏話などここだけの話を存分とお楽しみください。 番組を聴いた感想や質問は、#UKPラジオ​ をつけてツイートしてください！ ▼UKPラジオ・プレイリスト：https://spoti.fi/2NKXxsy​ ▼UKPラジオ・Twitterアカウント：https://twitter.com/ukp_radio​​​

A classic interview with my Tang Soo Do instructor Mr. Dennis Ichikawa... Enjoy

Welcome back to Open the Voice Gate! Case (https://twitter.com/_inyourcase) and Mike (https://twitter.com/fujiiheya) are back with an update on the comings and goings of Dragongate. Dragongate has come up on the beginning of March and their first big events of the year! Before Case and Mike get to that, they review the 2/26 debut in Kobe Tokiwa Arena including K-1 participation, a Dr. Muscle appearance, and we try to answer the question if someone can stop the Ichikawa. After that, they look ahead to the 3/4 Korakuen Hall show with the debut of YAMATO & Dragon Kid's new unit. Concluding the show, the preview the four title matches across the two nights of Champion Gate on 3/6 and 3/7! Our podcast provider, RedCircle, offers the listeners the option to sponsor the show. Click on “Sponsor This Podcaster” at https://redcircle.com/shows/open-the-voice-gate and you can donate a single time, or set up a monthly donation to Open the Voice Gate! Please Rate and Review Open the Voice Gate on the podcast platform of your choice and follow us on twitter at https://twitter.com/openvoicegate. Advertising Inquiries: https://redcircle.com/brands Privacy & Opt-Out: https://redcircle.com/privacy

This podcast episode explores the foundational concepts of finding a sense of self and place as the cornerstone of participating more fully in environmental activism.

In this episode Jack Mattingly follows up on The Landing, the Boeing Employees Occult Affinity Group's ritual and the heroics of derby regular Bud Ichikawa. He also answers a *very* important question about Somnos! Sponsored by the John Jay and Catherine T. MacArthur Foundation.

Mariko Ichikawa, a sustainable fashion designer living in New York City

Taichi Ichikawa is the co-founder of World Road Inc. and the director of World Dream Project, based in Japan. “Building the world into a single school” is the vision of himself and the company. To achieve the vision, he is currently working on a worldwide education book project called World Dream Project, which gathers 196 dreams with stories from 196 countries into one book promoting SDGs. The book will be published in 2021 and it's planned to distribute schools all over Japan and also launch worldwide to become a next-gen's textbook. Read his story here: https://the-nwg.com/2020/09/13/taichi-ichikawa/

Salve, rapaziada! Quando falamos em ciência, os primeiros nomes que vêm a mente, quase sempre, são de homens. Einstein, Lavosier, Alexander Fleming, Lewis entre diversos outros. Mas quais são as principais mulheres? Neste episódio vamos debater nomes tão importantes quanto Marie Curie. Vamos falar sobre as principais dificuldades da mulher nesse ambiente, e trazer alguns dados que podem indicar que estamos vivendo uma época de transição. Siga a gente em nossas redes sociais! @linumpaper no intagram e no twitter. Referências [1] As cientistas: 50 mulheres que mulheres mudaram o mundo. Rachel Ignotofsky. Blucher (2017); [2] Breve história de quase tudo. Bill Bryson. Companhia das letras (2017); [3] J. Huang, A. J. Gates, R. Sinatra, and A. L. Barabási, “Historical comparison of gender inequality in scientific careers across countries and disciplines,” Proc. Natl. Acad. Sci. U. S. A., vol. 117, no. 9, pp. 4609–4616, 2020, doi: 10.1073/pnas.1914221117; [4] L. Massarani, A. E. Pedreira, and Y. Castelfranchi, “Cientistas na TV: como homens e mulheres são representados no Jornal Nacional e no Fantástico,” Cad. Pagu, vol. 56, pp. 1–34, 2019; [5] E. Y. Ichikawa, J. M. Yamamoto, and M. C. Bonilha, “Ciência, Tecnologia e Gênero: Desvelando o Significado de Ser Mulher e Cientista,” Serviço Soc. em Rev., vol. 11, no. 1, pp. 1–15, 2008; [6] F. F. da Silva and P. R. C. Ribeiro, “Trajetórias de mulheres na ciência: ‘ser cientista' e ‘ser mulher,'” Ciência Educ., vol. 20, no. 2, pp. 449–466, 2014, doi: 10.1590/1516-73132014000200012.

On this week's episode, Jules and Madi chat with the fabulous Mariko Ichikawa, buyer-turned-designer. Mariko graduated from Penn and began her career in product development at Macy's (sound familiar?), soon becoming a buyer in the home department at Bergdorf Goodman. Feeling the need to spice things up, Mariko picked up and moved to Dubai, where she familiarized herself with a whole new international market, collaborating with colleagues from England, France, Lebanon, and Egypt, amongst others. Back in NYC, Mariko worked as a buyer for designer RTW at Barneys before creating her own line of beautiful, repurposed, authentic Japanese kimonos. Her designs have been seen on celebs like Karamo Brown of Queer Eye. Tune in to hear Mariko share how she continues to go after it through career ups and downs and her insanely contagious laugh. Follow her on Instagram @marikoichikawanyc and shop or browse her amazing designs at marikoichikawa.com.

Dr. Barnes spotlights 63 year-old Lona Ichikawa and her Ideal protein Journey to Life Possible! Talk about "It's never too late!" She is probably running circles around many people half her age! And her big dream that is now pursuing will knock your socks off and inspire you to greater things!In this episode we discuss how the Ideal Protein protocol, more than any other weight loss program has the ability to "Reset" your metabolism and this can have beneficial effects on so many common health conditions. If you are interested in pursuing this topic further, please click this link to an IP Health talk I gave with Dr. Dolores Zumbado about "The Power of the Protocol.

On March 26th 2007 the body of Lindsay Hawker was found in a bathtub filled with soil on the balcony of a fourth floor apartment in Ichikawa, a suburb near Tokyo. Lindsay had moved to Japan five months earlier to teach English. Despite almost 10 police officers at the scene the killer managed to escape and evade police for the next 2 and a half years. SPONSORS: Hero Cosmetics - use code CRIMELAPSE15 for 15% off on herocosmetics.comBest Fiends mobile puzzle game available on apple app store and google play store. PROMO:True Crime? NHOI https://open.spotify.com/show/5JmYa70Mq92R4B4DsiOiRn?si=G8l0HWcnRyS0w5-EEkDNGASOCIAL MEDIA: Twitter: https://twitter.com/crimelapsepod Facebook: https://facebook.com/crimelapsepodcast Instagram: https://instagram.com/crimelapsepodcast Sources: http://news.bbc.co.uk/2/hi/uk_news/6502219.stm https://web.archive.org/web/20070515040153/http://news.sky.com/skynews/article/0%2C%2C30000-1257881%2C00.html https://www.smh.com.au/world/bath-of-sand-murder-it-was-suffocation-20070330-gdpsos.html https://www.dailymail.co.uk/news/article-476722/British-teacher-buried-bath-sand-tortured-hours-sadistic-killer.html Tokyo Hostess: Inside the shocking world of Tokyo nightclub hostessing By Clare Campbell https://www.dailymail.co.uk/news/article-2011006/Lindsay-Hawker-trial-Tatsuya-Ichihashi-admits-raping-suffocating-British-teacher.html https://japantoday.com/category/crime/ichihashi-gets-life-for-murder-of-british-woman https://www.japantimes.co.jp/news/2013/11/02/national/crime-legal/tatsuya-ichihashi-killer-on-the-run/#.XmUglxP7RN0 https://www.theguardian.com/uk/2011/jul/04/japanese-man-lindsay-ann-hawker-murder https://www.japantimes.co.jp/news/2013/11/02/national/crime-legal/crime-and-punishment/#.XmYlLRP7SqA https://www.dailymail.co.uk/news/article-2013608/Lindsay-Hawker-murder-Mother-reveals-bath-2-years-after.html https://www.coventrytelegraph.net/news/coventry-news/lindsay-hawker-dad-visits-murder-3092563 Bodies in the Back Garden - True Stories of Brutal Murders Close to Home By Nigel Cawthorne https://www.theguardian.com/world/2009/nov/10/japan-murder-plastic-surgery-hawker https://www.dailymail.co.uk/news/article-450899/Parents-release-dove-funeral-murdered-teacher-Lindsay-Hawker.html https://www.dailymail.co.uk/news/article-1226599/Japanese-police-arrest-prime-suspect-Tatsuya-Ichihashi-murder-British-teacher-Lindsay-Hawker-years-run.html https://www.theaustralian.com.au/news/world/japanese-killer-tatsuya-ichihashi-makes-plea-to-british-victim-lindsay-hawkers-family/news-story/c27367291fece0920bfeb001da347d23 https://www.dailymail.co.uk/news/article-2010855/Tatsuya-Ichihashi-murder-trial-Lindsay-Hawkers-parents-arrive-Japan.html https://www.independent.co.uk/news/world/asia/im-sorry-says-body-in-bathtub-killer-tatsuya-ichihashi-as-he-faces-family-in-court-2306994.html https://www.theguardian.com/world/2011/jul/21/lindsay-hawker-killer-jailed-life https://www.dailymail.co.uk/news/article-2013013/Lindsay-Hawkers-killer-Tatsuya-Ichihashi-sentenced-life-guilty-murder-verdict.html https://theseoultimes.com/ST/?url=/ST/db/read.php%3fidx=10849 https://www.japantimes.co.jp/news/2011/07/22/national/ichihashi-gets-life-for-hawker-rape-murder/#.XmqyeRP7Su4 https://www.bbc.com/news/uk-england-coventry-warwickshire-17673492 https://www.standard.co.uk/news/on-cctv-the-japanese-killer-of-lindsay-hawker-days-before-murder-7253837.html https://www.theguardian.com/world/2011/jul/21/lindsay-hawker-killer-jailed-life https://www.telegraph.co.uk/news/worldnews/asia/japan/8651279/Tatsuya-Ichihashi-profile.html https://www.independent.ie/world-news/asia-pacific/father-wont-rest-until-daughters-killer-caught-26272822.html https://www.theguardian.com/world/2009/nov/10/japan-murder-plastic-surgery-hawker https://www.youtube.com/watch?v=IymApHDhkYI https://www.youtube.com/watch?v=tQOu-zg1Hj0 https://reuters.screenocean.com/record/461622 https://www.youtube.com/watch?v=C_p2oiSckNs https://www.youtube.com/watch?v=uFdUmsJg9AA https://www.youtube.com/watch?v=Ugg6sNKPekw https://www.youtube.com/watch?v=0xjnI1sd7X0

This week we wrap this series up with a look at the changes in the feminist movement during the US Occupation of Japan, and with a look at the postwar careers of Ichikawa Fusae and Hiratsuka Raicho.  Show notes here.

This week, we continue our exploration of the life of Hiratsuka Raicho, and add a new character to our cast: Ichikawa Fusae. How did these two women navigate the tricky waters of 1920s and 1930s Japanese politics, and what obstacles did they encounter along the way?  Show notes here.

In this episode, I'm meeting with Nina Ichikawa, Executive Director at the interdisciplinary research, action and education institute The Berkeley Food Institute. They seek to transform food systems to expand access to healthy, affordable food and promote sustainable and equitable food production. Berkeley Food Institute empowers new leaders with capacities to cultivate diverse, just, resilient, and healthy food systems. We're talking about how to work with food policy to change the public health crisis caused in part by unhealthy diets, why soil health is so important, the different food activities on the UC Berkeley campus and what every single person can do to contribute to a better food system. Host is Elise Johanson. For updates follow Elise Vega.

Nina Ichikawa is shaping the conversation about the future of California farming in many different ways. She's the Interim Executive Director at the Berkeley Food Institute, a member of the Farmer Justice Collaborative, the great grand-daughter of influential Japanese American flower growers, as well as a writer about Asian-American food histories. And she’s one of the most insightful thinkers about current issues in California food and farming. Tune in to this Cal Ag Roots episode to find out why Nina wants us all to be telling many more stories about California.

Fumiko Ichikawa is Co-Founder and Managing Director at Re:public, think and do tank. She has studied human-computer interaction, and she has been the practitioner of ethnographic research in Japan and around the world. After the financial crisis and great earthquake that took place in Northern Japan in 2011, Fumiko co-founded Re:public. The company extensively work with cities and regional governments, where conducting research together with people are the critical part of developing an ecosystem of people driving change, innovation, and quality of life. In today's episode we talk to Fumiko about how a natural disaster in Japan was her catalyst for a career transition from a researcher in the technology space to a facilitator of urban innovation with her own company Re-public; her involvement with the Fukuoka innovation studio; the type of relationships people build with cities, citizenship, identity and craftsmanship. Mentioned in Podcast: Things That Make Us Smart: Defending Human Attributes in the Age of the Machine, Don Norman 2011 earthquake in Japan The Modernist City: An Anthropological Critique of Brasilia, James Holston The Craftsman, Richard Sennett Fumiko's work: https://re-public.jp/ http://new-normal.life/ (Translation available) Social media and other links: https://www.linkedin.com/in/fumikoichikawa/ https://www.instagram.com/furbiko/ https://www.epicpeople.org/article_author/fumiko-ichikawa/

Martin is joined by master poster designer and dilm enthusiast Tony Stella to discuss Kon Ichikawa 1963 film, Revenge of a Kabuki Actor. They cover the film's unexpectedly pulp serial roots, talk about unlikely heroes and archetypical villains, and look at how the film fits into Kon Ichikawa's long and varied career.

Goffredo Fofi racconta "L'arpa birmana" (1956) di Kon Ichikawa, un film unico nella storia del cinema che esprime una filosofia non violenta nei confronti della guerra. "L'arpa birmana" narra la storia di un soldato, unico sopravvissuto del suo...

BBC News menu Valentine's Day: Japan falling out of love with 'obligation chocolates' By Tim McDonaldBBC News  13 February 2019   Business Share this with Email Share this with Facebook Share this with Twitter Share this with Whatsapp Image copyrightGETTY IMAGES Around the world, people use chocolate treats to express sweet nothings on Valentine's Day. But in Japan, it's a little more complicated. On Valentine's Day, only women give chocolate, and not just to their partners, but to their male colleagues too. Critics say the practice sucks all the fun out of Valentine's Day and instead turns it into a dreary duty where women risk offending co-workers if they leave someone out. Others say "giri choco", which translates to "obligation chocolate" is a little misunderstood, and besides, it's slowly fading as women opt to give chocolate to their friends instead. 'Obligation chocolate' Of course, giving chocolate on Valentine's Day can also be a romantic gesture. Women will often give "honmei choco" or "true feelings chocolate" to their partners. But giri choco is more about expressing appreciation to male colleagues. A 2017 survey by multinational firm 3M found that nearly 40% of female respondents planned to give giri choco to a co-worker. Image copyrightGETTY IMAGES For most, it was a simple thank you "for general help and support". Others felt it helped promote a smoother workplace, while a small minority felt it would be awkward not to take part. Not so sweet Chocolate journalist Ayumi Ichikawa says many women have no problem with giri choco. After all, Japan has a gift-giving culture, so it doesn't seem out of place. "It's part of our tradition to give presents to people who 'help us'... and we have a habit of giving friends and acquaintances gifts every now and then to show our gratitude for 'looking after us'... without any sense of romantic love." But others are troubled by the custom. "Some consider the ritual burdensome, feeling you must do this, so the chocolate becomes a duty," Ms Ichikawa says. Women 'victims in 63% of romance scams' - BBC News Valentine's Day revenge for ex-lovers Still, University of Shizuoka professor Sejiro Takeshita says the tradition isn't as "unfair as it looks". On 14 March Japan celebrates White Day, when men give chocolates to women and, Prof Takeshita says, "ladies can get their vengeance". Image copyrightGETTY IMAGES Power dynamics In a 1996 study of "office women" sociologist Ogasawa Yuko argued giri choco is a way for women to exercise power over men by ranking them. The ones they admire would get chocolate, while the incompetent ones could buy their own treats. "In other words, it could be seen as one of the few opportunities for women to exercise power over men, resisting prevailing gendered norms," says Sachiko Horiguchi, an anthropologist at Temple University Japan. More than two decades later, this might seem a little less appealing to Japanese working women. "I am not sure if these professional women feel obliged to 'exercise their power' through giri choco gift giving," says Ms Horiguchi. Chocolate battle Last year the practice attracted an unexpected critic in the form of Belgian chocolatier Godiva. The company took out a full page ad calling for an end to giri choco. "Valentine's Day is supposed to be a day when you tell someone your pure feelings. It's not a day on which you're supposed to do something extra for the sake of smooth relations at work," the ad said. They followed up this year with a tweet to Yuraku Confectionery, the makers of Black Thunder, a low-cost chocolate and self-styled "king of giri choco". Image copyrightGETTY IMAGES The tweet encouraged employees of Yuraku to buy Godiva to give to someone they loved, prompting Yuraku to add "officially recognized by Godiva as obligation chocolate" to its Twitter description. Chocolate makers have an obvious stake in the discussion and it was commercial interests - initially depa --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/wwn/message

Do you take the time to really reflect on your work and consciously think if the things you're doing are impactful? I guess we all recognise this to a certain degree: When you're caught up with the day to day operational stuff you rarely of (or rather take) the time to think critically about what you're doing. And we all know where that sometimes leads to... So in this episode Fumiko Ichikawa talks about ways to find more balance between thinking and doing as a design practitioner. We also look at another very interesting topic in this episode... A common challenge in a lot of service design projects is that as soon as the external agency leaves, the project loses most of it's momentum. Fumiko shares, from her own experience, a very effective way to increase the chance that the solution you're working on actually stays alive once you're gone. The answer to this will likely give you a different perspective on what a deliverable of a service design project might be. And finally we talk about the tendency of stakeholders to jump from research mode into ideation / solution mode. What can you do to allow for more time and deeper reflection? This episode is filled with great practical insights so I really hope you enjoy it! ---------------------------------------- EPISODE GUIDE 05:00 - The first encounter with Service Design. 06:20 - How can we balance thinking and doing? 13:20 - What if we can establish community through the design process? 20:35 - Why do we need to reframe? 28:35 - Big Question: How do YOU balance thinking and doing? ---------------------------------------- LINKS FROM THE EPISODE Fumiko on LinkedIn ➜ https://go.servicedesignshow.com/llac1 Re:public ➜ http://re-public.jp/ Reach Network ➜ https://go.servicedesignshow.com/r-io_ MORE EPISODES Enjoyed the show? Take a look at some of the other episodes. https://go.servicedesignshow.com/podcast YOUTUBE Every episode of the Service Design Show is also available as via the official YouTube channel. https://go.servicedesignshow.com/youtube FACEBOOK Check the Facebook page where you'll find more content and can discuss the episodes. https://go.servicedesignshow.com/facebook INSTAGRAM Get an exclusive behind the scenes look of the Show. https://go.servicedesignshow.com/instagram ---------------------------------------- [FREE COURSE] HOW TO EXPLAIN SERVICE DESIGN Learn what it takes to get your clients, colleagues, managers, CEOs and even grandmas as excited about service design as you are! https://servicedesignshow.com/free-course

Etsuko's interview offers an insightful look into public art commissions, the importance of vetting galleries before you work with them, and how to tackle brand management even as your career evolves. The post Maintaining Momentum in an Evolving Art Career – Etsuko Ichikawa appeared first on Clark Hulings Fund.

Dove si parla della condanna per furto degli animalisti che liberarono alcuni Cani dell'allevamento Gren Hill, di Seaworld che nel 2017 elimina gli spettacoli con le Orche a San Diego, con MARIA PEREGO, cretrice di Topo Gigio, del suo libro IO e Topo Gigio, Vita artistica e privata di una donna straordinaria, Marsilio Editori, di Topi, di Gatti, di Gatti, di Michael Jackson, di Louis Armstrong, di Ed Sullivan, di Ichikawa e scopriamo che Maria ama i Cani ma avrebbe voluto essere un Topo col carattere di Gigio

Dove si parla della condanna per furto degli animalisti che liberarono alcuni Cani dell'allevamento Gren Hill, di Seaworld che nel 2017 elimina gli spettacoli con le Orche a San Diego, con MARIA PEREGO, cretrice di Topo Gigio, del suo libro IO e Topo Gigio, Vita artistica e privata di una donna straordinaria, Marsilio Editori, di Topi, di Gatti, di Gatti, di Michael Jackson, di Louis Armstrong, di Ed Sullivan, di Ichikawa e scopriamo che Maria ama i Cani ma avrebbe voluto essere un Topo col carattere di Gigio

Dove si parla della condanna per furto degli animalisti che liberarono alcuni Cani dell'allevamento Gren Hill, di Seaworld che nel 2017 elimina gli spettacoli con le Orche a San Diego, con MARIA PEREGO, cretrice di Topo Gigio, del suo libro IO e Topo Gigio, Vita artistica e privata di una donna straordinaria, Marsilio Editori, di Topi, di Gatti, di Gatti, di Michael Jackson, di Louis Armstrong, di Ed Sullivan, di Ichikawa e scopriamo che Maria ama i Cani ma avrebbe voluto essere un Topo col carattere di Gigio

This week we are joined by a guest co-host in Shannon’s absence. Matt Herman talks to us about the recent earthquake in Nepal. We had to record in an empty classroom, so sorry about the audio quality. We’ll be back to our normal location and setup next week! Earthquake USGS Event Page Plate Map PAGER Report John’s Ground Motion Movie Everest Avalanche Movie Matt uses INSAR and GPS to look at static displacements. USArray Ground Motion Visualizations Coulomb Stress Geologic Cross-section Rayleigh-Benard Convection Fun Paper Friday This week we read about a mysterious mist above your coffee and tea. This is a great reason to film your coffee cup! Umeki, T., Ohata, M., Nakanishi, H., & Ichikawa, M. (2015, January 2). Dynamics of microdroplets over the surface of hot water. arXiv.org. http://doi.org/10.1038/srep08046 Contact us: Show - www.dontpanicgeocast.com - @dontpanicgeo - show@dontpanicgeocast.com John Leeman - www.johnrleeman.com - @geo_leeman Shannon Dulin - @ShannonDulin

Jack Straw resident artist Etsuko Ichikawa discusses her residency project, the film and Jack Straw New Media Gallery installation Echo at Satsop.

Jack Straw resident artist Etsuko Ichikawa discusses her residency project, the film and Jack Straw New Media Gallery installation Echo at Satsop.

Jack Straw resident artist Etsuko Ichikawa discusses her residency project, the film and Jack Straw New Media Gallery installation Echo at Satsop. The post Jack Straw New Media Gallery Interview : Etsuko Ichikawa appeared first on Jack Straw Cultural Center.

Jack Straw resident artist Etsuko Ichikawa discusses her residency project, the film and Jack Straw New Media Gallery installation Echo at Satsop.

Curatorial assistant Noriko Sanefuji interviews Grant Ichikawa, a US veteran who enlisted after being relocated to a Japanese American internment camp with his family in 1942. Allowed to join the army after a need for interpreters, Mr. Ichikawa served proudly and in 2011, he and other veterans were awarded the Congressional Gold Medal for his service.

This Japanese film directed by Jun Ichikawa is based on the short story by Haruki Murakami. In it a reclusive illustrator (Issei Ogata) falls in love with a young woman (Rie Miyazawa) who addictively shops for clothing. Haruki Murakami was intrigued by the name Tony Takitani when, at a garage sale on Maui, he found a yellow T-shirt that said, "Tony Takitani, House (D)." At the time, Takitani was running for office. Murakami decided to write the man's life story as this novel. Stream online: https://amzn.to/2XHMxlW Become a Patron: https://www.patreon.com/mfrbooksandfilm?fan_landing=true

This Japanese film directed by Jun Ichikawa is based on the short story by Haruki Murakami. In it a reclusive illustrator (Issei Ogata) falls in love with a young woman (Rie Miyazawa) who addictively shops for clothing. Haruki Murakami was intrigued by the name Tony Takitani when, at a garage sale on Maui, he found a yellow T-shirt that said, "Tony Takitani, House (D)." At the time, Takitani was running for office. Murakami decided to write the man's life story as this novel. Stream online: https://amzn.to/2XHMxlW

Das Endothel dient im ruhenden Zustand dem Gefäß als Barriere, die jedoch durch lokale Schädigung wie Trauma, Entzündung oder Ischämie aufgelöst werden kann (Klinke, 1996; Ley, 1996). Dieses Phänomen wird auch im Zusammenhang mit der Reperfusion zuvor ischämischer Myokardareale als so genannter Reperfusionsschaden beobachtet (Jennings, 1985; Schurmann, 1997). Erst das aktivierte Endothel ermöglicht Prozesse wie das Rolling, Sticking und die Migration zuvor frei fließender PMN und Thrombozyten, die über eine Reihe von Adhäsionsmolekülen wie u.a. E-Selektin und ICAM-1 vermittelt werden (Adhäsionskaskade, Sluiter, 1993; Froese, 1994; Fuster, 1996). Vorausgehende Untersuchungen konnten zeigen, dass die Endothelaktivierung in zwei Phasen verläuft, einer akuten nach Sekunden bis Minuten (Typ I) und einer subakuten nach Stunden bis Tagen (Typ II, Pober, 1990; Ichikawa, 1997). Akute Mechanismen verwenden die Freisetzung bereits bestehender Mediatoren wie PAF, Leukotriene, H2O2 und posttranslationale Modifikationen, für die subakuten Effekte ist jedoch eine Neusynthese von Zytokinen und Adhäsionsmolekülen erforderlich (Nawroth, 1993; Kukielka, 1994). Dabei spielen Transkriptionsfaktoren wie NFκB eine bedeutende Rolle (Chen, 1998; Karin, 1999). In der vorliegenden Arbeit wurde zunächst ein Zellkulturmodell mit neonatalen Rattenendothelzellen und humanen Umbilkalvenenzellen bzw. einer humanen Endothelzelllinie etabliert, womit auch Mechanismen der Hypoxie und Reoxygenierung (Reperfusionssituation) simuliert werden konnten (vgl. Material und Methoden 3.1 und 3.2). Eigens hergestellte HVJ-Liposomen (Dzau, 1996; Morishita, 1997) zeigten im Vergleich zu kommerziellen Reagenzien (Effectene, Qiagen) keine befriedigende Transfektionseffizienz, weshalb das Modell mit letzteren umgesetzt wurde (vgl. Ergebnisse 4.1 und 4.2). Nach Transfektion von Reportergenkonstrukten für ICAM-1 wurde die Expression dieser Adhäsionsmoleküle nach unterschiedlicher Zellstimulation beobachtet und mittels einer Renilla- bzw. Firefly-Luciferasemarkierung luminometrisch gemessen (vgl. Material und Methoden 3.3 und 3.7). Auf die Stimulation mit TNFα, PMN, Thrombozyten und/oder Hypoxie bzw. Reoxygenierung reagierten diejenigen ICAM-1-Reportergenkonstrukte in signifikantem Ausmaß, die eine entsprechende Bindungsdomäne für den Transkriptionsfaktor NFκB enthielten. Dort kam es regelmäßig zu einer Hochregulation der ICAM-1-Expression als Parameter einer Mehrsynthese dieser Adhäsionsmoleküle (vgl. Ergebnisse 4.3). Mittels Myeloperoxidase-Messungen (leukozytenspezifisches Enzym) konnten insbesondere adhärente PMN für diese Prozesse verantwortlich gemacht werden (vgl. Ergebnisse Abb. 4.10). Zur Beeinflussung dieser subakuten Endothelaktivierung wurden so genannte NFκB-Decoy-Oligodinukleotide eingesetzt (vgl. Material und Methoden 3.6), die teilweise die DNA-Bindungssequenz des intrazellulären NFκB-Komplex besetzten. Dadurch kam es zwar noch zu einer Translokation des NFκB-Komplex in den Zellkern, die konsekutive ICAM-1-Transkription und Proteinsynthese wurde jedoch verhindert (Tomita, 2003; Morishita, 2004). Diese NFκB-Decoy-ODN bewirkten nach Transfektion in zuvor mit TNFα, PMN, Thrombozyten und/oder Hypoxie bzw. Reoxygenierung aktivierte Endothelzellen eine signifikante Reduktion der ICAM-1 Reportergenexpression. Noch deutlichere Effekte wurden durch eine Veresterung der NFκB-Decoy-ODN (Phosphothioat als Proteinaseinhibitor) oder eine entsprechend frühere Transfektion (bis 48h vor Zellstimulation) gemessen (vgl. Ergebnisse 4.4). Der akuten Interaktion zwischen Endothel und PMN bzw. Thrombozyten wird im klinischen Alltag u.a. mit GpIIb/IIIa-Rezeptorantagonisten (Tirofiban und Abciximab) begegnet (Nigam, 2002; Schwarz, 2002). In unserem in vitro-Zellkulturmodell bewirkten diese Substanzen nach Endothelstimulation eine (in unterschiedlichem Ausmaß) verringerte Adhäsion von PMN und Thrombozyten am Endothel (vgl. Ergebnisse 4.5). Zudem zeigten sie überraschender Weise auch einen inhibitorischen Effekt auf die ICAM-1-Reportergenexpression und damit auf die subakute Endothelaktivierung (vgl. Ergebnisse 4.6). Abciximab war dabei Tirofiban und einem CD18-Antikörper (IB4) signifikant überlegen (vgl. Ergebnisse Abb. 4.19). Diese Daten legten die Überlegung nahe, beiden Strategien (Adhäsionshemmer vs. NFκB-Decoy-ODN) bezüglich ihres ICAM-1-inhibitorischen Potentials am Endothel zu vergleichen: in unseren Untersuchungen war die Transfektion von NFκB-Decoy-ODN der Gabe von Adhäsionshemmern (Abciximab, Tirofiban oder CD18-Antikörper) überlegen (vgl. Ergebnisse Abb. 4.20). Die Kombination beider Strategien (Adhäsionshemmer und NFκB-Decoy-ODN) zeigte geringe, zusätzliche, ICAM-1-inhibitorische Effekte (vgl. Ergebnisse Abb. 4.21). Die Applikation von Oligodinukleotiden wird inzwischen als eine viel versprechende Therapie insbesondere ischämiebedingter, kardiovaskulärer Erkrankungen gesehen: nach Transfektion von NFκB-Decoy-ODN wurden bislang bereits positive Effekte auf die Myokardfunktion (Sakaguchi, 2001), koronare Restenoserate (Rutanen, 2002) und den Myokardinfarkt selbst (Morishita, 1997) gezeigt. Eine aktuelle Patientenanwendung nach koronarer Stentimplantation (Jun-Ichi, 2004) ergab bei zusätzlicher Transfektion von NFκB-Decoy-ODN gegenüber dem konventionell versorgten Myokardareal geringere Restenoseraten.

My Father's Shop by Satomi Ichikawa

Welcome back to Open the Voice Gate! Case (https://twitter.com/_inyourcase) and Mike (https://twitter.com/fujiiheya) are back with an update on the comings and goings of Dragongate. Dragongate has come up on the beginning of March and their first big events of the year! Before Case and Mike get to that, they review the 2/26 debut in Kobe Tokiwa Arena including K-1 participation, a Dr. Muscle appearance, and we try to answer the question if someone can stop the Ichikawa. After that, they look ahead to the 3/4 Korakuen Hall show with the debut of YAMATO & Dragon Kid’s new unit. Concluding the show, the preview the four title matches across the two nights of Champion Gate on 3/6 and 3/7! Our podcast provider, RedCircle, offers the listeners the option to sponsor the show. Click on “Sponsor This Podcaster” at https://redcircle.com/shows/open-the-voice-gate and you can donate a single time, or set up a monthly donation to Open the Voice Gate! Please Rate and Review Open the Voice Gate on the podcast platform of your choice and follow us on twitter at https://twitter.com/openvoicegate. Support this podcast at — https://redcircle.com/open-the-voice-gate/donations

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.22.056432v1?rss=1 Authors: Yamashita, A., Sakai, Y., Yamada, T., Yahata, N., Kunimatsu, A., Okada, N., Itahashi, T., Hashimoto, R.-i., Mizuta, H., Ichikawa, N., Takamura, M., Okada, G., Yamagata, H., Harada, K., Matsuo, K., Tanaka, S., Kawato, M., Kasai, K., Kato, N., Takahashi, H., Okamoto, Y., Yamashita, O., Imamizu, H. Abstract: Many studies have highlighted the difficulty inherent to the clinical application of fundamental neuroscience knowledge based on machine learning techniques. It is difficult to generalize machine learning brain markers to the data acquired from independent imaging sites, mainly due to large site differences in functional magnetic resonance imaging. We address the difficulty of finding a generalizable major depressive disorder (MDD) brain network markers which would distinguish patients from healthy controls (a classifier) or would predict symptom severity (a prediction model) based on resting state functional connectivity patterns. For the discovery dataset with 713 participants from 4 imaging sites, we removed site differences using our recently developed harmonization method and developed a machine learning MDD brain network markers. The classifier achieved 70% generalization accuracy, and the prediction model moderately well predicted symptom severity for an independent validation dataset with 449 participants from 4 different imaging sites. Finally, we found common 2 functional connections between those related to MDD diagnosis and those related to depression symptoms. The successful generalization to the perfectly independent dataset acquired from multiple imaging sites is novel and ensures scientific reproducibility and clinical applicability. Copy rights belong to original authors. Visit the link for more info