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Andrew Maclean is joined by Brian Graham as they take more of your calls on Lawrence Shankland signing for Rangers, Celtic's managerial search and Brian's departure from Falkirk to rejoin Ross County.Plus, the Beat The Pundit Summer League continues and we give away another pair of tickets to Superscoreboard Off-Air.
Gordon Duncan, Gordon Dalziel & Brian Graham are live at Hampden and Andrew MacLean, Hugh Keevins and Cammy Bell are in the studio to bring you coverage of the 2026 Scottish Cup Final between Celtic and Dunfermline
Gordon Duncan, Gordon Dalziel & Brian Graham are live at Hampden and Andrew MacLean, Hugh Keevins and Cammy Bell take your calls as we react to Celtic securing the double and winning the Scottish Cup Final
Gordon Duncan, Marvin Bartley and Brian Graham are in the studio on the day Hearts released a statement saying they're concerned with the "troubling precedent whereby a pitch invasion can determine the duration of a football match" after their last-day title loss to Celtic.Meanwhile, a Rangers fan says the Jambos weren't "robbed" of the title, they were "MUGGED".Plus, there's reaction to Motherwell being approached by Toulouse looking to appoint Jens Berthel Askou and we look ahead to Partick Thistle's play-off final first leg with St Mirren on Thursday.
Andrew Maclean, Brian Graham and Alex Rae are in the studio following Celtic ending Rangers' title hopes after coming from behind to win at Parkhead on Sunday.On the phones, Gers fans vent their frustrations with their team, manager and the referees; Hoops fans say they're favourites for the title; and Hearts fans slam their denial of a penalty against Motherwell on Saturday night as they chase the Scottish Premiership title.
Gordon Duncan, Brian Graham and Gordon Dalziel are in the studio, as we react to news linking the Rangers manager to Germany's 18th-ranked Bundesliga side. Plus, thoughts on Motherwell's game plan against Hearts, and Lawrence Shankland's chances of starting for Scotland at the World Cup.We'll have a Full-Time Teaser and Beat The Pundit after 7pm.
Gordon Duncan, Brian Graham and Gordon Dalziel are in the studio, as we react to comments from Hibs' captain Joe Newell saying his side won't "lie down" to Celtic. Plus, we're hearing from Kilmarnock boss Neil McCann, who says his side are in positive mood as they look to escape the relegation play-off spot.We'll also have Beat The Pundit, and the Full-Time Teaser after 7pm.
Andrew Maclean is joined by Brian Graham and Jim Duffy in the studio as they bring you coverage of Ranger v Motherwell's second half and the game between Hibs and Hearts. After Celtic winning the day before could both Ranger and Hearts follow?The Lines light up with fans reactions after the full time whistle goes in the earlier kick off at Ibrox. Beat the Pundit as well as Jim Duffy takes on Jordon from Dalkieth.
Gordon Duncan is joined by Brian Graham and Gordon Dalziel as they discuss Rangers' captain James Tavernier's future with news breaking that he has not been offered a new deal yet, There's talk on Celtic's title chances and a rogue shout for who should replace Martin O'Neill next season.Plus Beat The Pundit & The Full Time Teaser
Gordon Duncan, Brian Graham and Gordon Dalziel take your calls!Three out of the four semi-finalists were on media duties...Neil Lennon slams SPFL over Dunfermline fixture pile-up, a cup final would be the 'icing on cake' for John McGlynn and can St Mirren upset Celtic again? Craig McLeish thinks so!
Brian Graham and Gordon Dalziel join Gordon Duncan on tonight's Clyde 1 Superscoreboard, as we react to comments from Motherwell manager Jens Berthel Askou calling for a clamp down on players acting "cynically or dishonestly". We're also reflecting on both of Scotland's recent friendly fixtures in preparation for the World Cup, and we're back to domestic football with a look ahead to this weekend's fixtures.Plus, your chance to win a signed ball after 7pm, and a Scotland-themed Full-Time Teaser.
Gordon Duncan, Brian Graham and Gordon Dalziel are in the studio as we react to Steve Clarke's Scotland squad announcement, and if he'll stay past the World Cup. Also, Raymond Mearns joins us on the show ahead of his Glasgow International Comedy Festival performance.Plus, Beat The Pundit and the Full Time Teaser. after 7.
Gordon Duncan, Brian Graham and Gordon Dalziel are here for night two of Old Firm fallout following Celtic's Scottish Cup win on Sunday.A Rangers fan fears he will never return to Ibrox after his daughter was almost hit by a bottle, with Brian sharing an anecdote about the trouble he witnessed.Meanwhile, a Celtic fan is full of praise for "character" Julián Araujo, and a St Mirren fan talks their progression to the semi-finals.
Gordon Duncan is joined by Brian Graham & Gordon Dalziel as there's more fallout from Sunday's dramatic Old Firm clash, There's talk about Kasper Schmeichel's future, Rangers title chances and we look ahead to Celtic's game with Aberdeen tomorrow.Plus Full Time Teaser & Beat The Pundit
Gordon Duncan, Gordon Dalziel and Falkirk striker Brian Graham are in the studio reacting to the decision to uphold the red card as well as all the big talking points left over from the weekend.Celtic supporters David and Jamie agree the decision was never going to be overturned but disagree with the red card, St Mirren supporter Ian wasn't happy with Callum Slattery and Chris was concerned about recent Heart's performances.
Gordon Duncan, Brian Graham and Simon Donnelly are in the studio as Martin O'Neill prepares for his 1,000th game in management.Derek McInnes says people wrong to dismiss Hearts' title chances and Motherwell travel to Aberdeen in Scottish Cup.
Andrew Maclean, Brian Graham & Jim Duffy are in the studio as the bring you reactions to Kilmarnock v Celtic. With Celtic coming back from two goals down to win it the listeners call in with their reactions to game. The panel brings you live action from Ibrox as Hearts travel to Govan for a top of the table clash. Gabriel Antoniazzi brings you the starting line ups along with the Half-time and full-time reports.All of that and more. Plus Beat The Pundit as well.
Andrew Maclean, Brian Graham & Alex Rae take your calls as we react live to Hearts and Celtic playing out a 2-2 draw and Rangers sealing a 3-0 victory at home to Dundee to close the gap on the leaders to 4 points
I believe Brian Graham scored from 5 yards out as the Bairns went to Rugby Park and returned with three points. Ross and John are here to talk about the 1-0 win against Kilmarnock in the company of former FTV commentator Lewis Connolly. Plus looking ahead to Dundee, talking transfers and there is rage quit on Falkirk Daft versus! Expect the unexpected! Behind the Wall – Behind the Bairns since 1985 Falkirk's best selection of fine wines lagers, craft and cask ales, fantastic value food and great service. Check out what's on www.behindthewall.co.uk Join the FFIT T8s https://www.facebook.com/groups/1803421196843918 Get the new Falkirk Daft t-shirt's: https://pintsnprints.co.uk/collections/falkirk-collection And Remember sign up for our Discord and Social Media: Discord - https://discord.com/invite/sVYbRzzusK Twitter/Insta/Facebook - @Falkirkdaft Get Merch: merch.falkirkdaft.co.uk For any sponsorship enquiries email sales@falkirkdaft.co.uk Subscribe to our YouTube channel and remember to leave a review where you get your podcasts. youtube.com/@falkirkdaft
We're delighted to welcome back old friend of the show Mark Wilson, in a different capacity to usual on Open Goal! Si Ferry sits down with the new Partick Thistle Manager to celebrate his Glen's Vodka SPFL Championship Manager Of The Month victory for October!We discuss Mark's whirlwind few months at Thistle, going from temporary co-Manager with Brian Graham last season to being appointed in the position on his own and now challenging for the top spot in the Championship!He talks us through the process of his appointment, the start to the season, giving up his media duties including Clyde 1 Superscoreboard with Gordon Dalziel to take the role, player recruitment including his old Celtic teammate, Tony Watt and building his backroom staff with recent Rangers coach Alex Rae joining as his assistant!A great and enjoyable insight and reunion with Mark Wilson in this one! Hosted on Acast. See acast.com/privacy for more information.
We're delighted to welcome back old friend of the show Mark Wilson, in a different capacity to usual on Open Goal! Si Ferry sits down with the new Partick Thistle Manager to celebrate his Glen's Vodka SPFL Championship Manager Of The Month victory for October!We discuss Mark's whirlwind few months at Thistle, going from temporary co-Manager with Brian Graham last season to being appointed in the position on his own and now challenging for the top spot in the Championship!He talks us through the process of his appointment, the start to the season, giving up his media duties including Clyde 1 Superscoreboard with Gordon Dalziel to take the role, player recruitment including his old Celtic teammate, Tony Watt and building his backroom staff with recent Rangers coach Alex Rae joining as his assistant!A great and enjoyable insight and reunion with Mark Wilson in this one! Hosted on Acast. See acast.com/privacy for more information.
Alison McConnell is joined by Alan Rough and Falkirk striker Brian Graham as he throws his support behind Rangers boss Russell Martin, questions the decision of Celtic fans to host silent protests and he looks ahead to this weekend when he will face off against the Ibrox side in the Scottish Premiership.
Heather Holloway, David Forrest, Jamie McDonald and Aaron Richardson are here to discuss our 3-0 win over Ayr United, Stuart Bannigan's booking, and of course, the Taylor Swift podcast that dropped. Also, Matt Greer speaks to Tom Hosie and Kieran Tuohy about Partick Thistle Women's start to life after Brian Graham.
Grand Island Superintendent Brian Graham on allowing a student's "God is Love" design for her student parking space full 155 Wed, 20 Aug 2025 19:58:05 +0000 2HRU02JKHOQsHuiPaCiUwjNrtBdd8bLX news & politics,news WBEN Extras news & politics,news Grand Island Superintendent Brian Graham on allowing a student's "God is Love" design for her student parking space Archive of various reports and news events 2024 © 2021 Audacy, Inc. News & Politics News False
Grand Island Superintendent Brian Graham on student fighting to put a religious message on her student parking space full 90 Fri, 15 Aug 2025 08:40:00 +0000 RnX8k4gGEfns3WvsBQZ4wFCYL8BQ0ABw news & politics,news WBEN Extras news & politics,news Grand Island Superintendent Brian Graham on student fighting to put a religious message on her student parking space Archive of various reports and news events 2024 © 2021 Audacy, Inc. News & Politics News False
On the show today we welcome Falkirk striker Brian Graham! We discuss Falkirk's start to the season and find out how Brian has adapted to being back in the Scottish Premiership. We also talk about the reaction Russell Martin will get from his Rangers playing following his comments at the weekend, and also discuss Tony Bloom's investment and his vow to split the Old Firm. Join PLZ Premium TODAY! You will receive exclusive benefits via PLZ Soccer YouTube - including member only video content, access to ask questions on our special live stream and special features before anyone else. Plus much more!
Gordon Duncan is joined by Brian Graham & Gordon Dalziel as they react to Rangers victory in Athens, breakdown Celtic closing in on Manchester City's Jahmai Simpson-Pusey, Brian give's us an insight into Falkirk preparation for the new season and Partick Thistle's Mark Wilson re-joins the panel..sort of
We are back, kind of...It's a one off mid close season podcast as Ross and John speak to Brad Spencer's Dad, former Scotland and Chelsea striker John Spencer. He gives us an insight into his career, his views on the team and what we can expect in the Premiership. That and the guys discuss the signings of Scott Bain and Brian Graham, season ticket sales and the return of the academy. Plus news on Falkirk Daft Live V and the boys big charity football match. Expect the Unexpected! Behind the Wall – Behind the Bairns since 1985 Falkirk's best selection of fine wines lagers, craft and cask ales, fantastic value food and great service. Check out what's on www.behindthewall.co.uk Join the FFIT T8s / 1803421196843918 Get the new Falkirk Daft t-shirt's: https://pintsnprints.co.uk/collection... And Remember sign up for our Discord and Social Media: Discord - / discord Twitter/Insta/Facebook - @Falkirkdaft Get Merch: merch.falkirkdaft.co.uk For any sponsorship enquiries email sales@falkirkdaft.co.uk Subscribe to our YouTube channel and remember to leave a review where you get your podcasts. / @falkirkdaft
Kevin Comer and Brian Graham are both frequent travelers on group trips organized by Agents of Innovation podcast host Francisco Gonzalez, who is also the founder & CEO of Fearless Journeys. In this unique podcast episode, the three recount personal and group trips and offer lots of great travel advice while recounting amusing stories -- some of which are almost hard to believe! You can also watch this episode on YouTube here: https://youtu.be/zGZWcKE1WAg Follow the Agents of Innovation podcast on: Instagram: www.instagram.com/innovationradio/ Twitter: twitter.com/agentinnovation Facebook: www.facebook.com/AgentsOfInnovationPodcast You can support this podcast and our Fearless Journeys community on our Patreon account: www.patreon.com/fearlessjourneys You can also join our network through the Fearless Journeys community at: www.fearlessjourneys.org Find Brian Graham on Instagram at @brianhgraham Find Kevin Comer on Instagram at @kevininFlorida
Have the FA Cup quarter-finals shown the importance of the competition? Mark Chapman is joined by Rory Smith, Chris Sutton and Monday Night Club debutant Joe Hart to discuss the weekend's FA Cup action. They look at why the FA Cup is so important for so many teams, and discuss the benefits of a range of teams lifting the trophy. Former Crystal Palace player and coach Shaun Derry drops by to discuss his former club's remarkable run to the semi final as they reach their second FA Cup semi final in four years. Arsenal's new sporting director is also a topic of conversation – how does the dynamic of the manager having a say in their appointment work? Hear from Mikel Arteta on his appointment. Joe also gives a masterclass in goalkeeping and the work goalkeepers put into preparing for a penalty shootout, and he remembers saving a penalty from Lionel Messi! Plus, after Brian Graham was appointed interim manager of Partick Thistle men (alongside Mark Wilson) until the end of the season, he joins the podcast to explain how he balances that with being the captain, leading goalscorer and women's team manager!TIME CODES:02:20 – The excitement of cup football 12:35 – Former Crystal Palace player and coach Shaun Derry 26:10 – Arsenal's new sporting director, Andrea Berta 36:45 – Joe's goalkeeping masterclass 45:20 – Football's busiest man, Brian GrahamBBC Sounds / 5 Live midweek Premier League commentaries:Tue 1 Apr 1945 Arsenal v Fulham on 5 Live, Tue 1 Apr 2000 Nottingham Forest v Man Utd on 5 Sports Extra, Tue 1 Apr 1945 Wolves v West Ham on BBC Sport website, Wed 2 Apr 2000 Liverpool v Everton on 5 Live, Wed 2 Apr 1945 Newcastle v Brentford on 5 Sports Extra, Wed 2 Apr 1945 Bournemouth v Ipswich on BBC Sport website.
Gordon Duncan is joined by Brian Graham & Roger Hannah as they take your calls and speak about the weekends action
Gordon Duncan is joined by Roger Hannah and Brian Graham as they build up to Scotland's crucial Nation's League tie with Poland and discuss the rumours of Philippe Clement being linked with the Belgium national team.
Gordon Duncan is joined by Gordon Dalziel & Brian Graham to look forward to Celtics away trip to Atalanta and Rangers home game against FCSB...
Gordon Duncan is joined by Hugh Keevins & Brian Graham to look forward to the weekends top flight action and discuss Ryan Kent being linked with a return to Rangers...
In this episode of School Business Insider, we take a deep dive into the evolving landscape of school security. Joining us are Dr. Brian Graham, Superintendent of Grand Island Central School District, and Brett Handell, Vice President of Sales at ZeroEyes, a company specializing in AI-driven weapon detection technology. Dr. Graham and Brett discuss how Grand Island has integrated advanced technologies like ZeroEyes to enhance school safety and the importance of balancing security measures with maintaining a welcoming environment for students. They also explore key trends in school security, including the use of artificial intelligence, proactive security measures, and fostering partnerships with law enforcement. If you're interested in how technology can transform the safety of school environments, this episode offers valuable insights into both the practical and technological advancements shaping the future of school security.Contact School Business Insider: Check us out on social media: LinkedIn Twitter (X) Website: https://asbointl.org/SBI Email: podcast@asbointl.org Make sure to like, subscribe and share for more great insider episodes!Disclaimer:The views, thoughts, and opinions expressed are the speaker's own and do not represent the views, thoughts, and opinions of the Association of School Business Officials International. The material and information presented here is for general information purposes only. The "ASBO International" name and all forms and abbreviations are the property of its owner and its use does not imply endorsement of or opposition to any specific organization, product, or service. The presence of any advertising does not endorse, or imply endorsement of, any products or services by ASBO International.ASBO International is a 501(c)3 nonprofit, nonpartisan organization and does not participate or intervene in any political campaign on behalf of, or in opposition to, any candidate for elective public office. The sharing of news or information concerning public policy issues or political campaigns and candidates are not, and should not be construed as, endorsements by ASBO Internatio...
Gordon Duncan is joined by Marvin Bartley, Brian Graham & SFA Head Of Referee Operations Willie Collum as they answer your questions.
Gordon Duncan is joined by Gordon Dalziel and Superscoreboard debutant Brian Graham.Rangers and Celtic both announce signings this evening. Plus we build up to the huge European games for St Mirren and Kilmarnock
Is the private office taking on a new and important role? Is it time for the private office to be reimagined? In this special episode, Doug shares part of a conversation we captured between designer Brian Graham and our very own, Molly Prior. Together, Brian and Molly chat about the rapid shift in management styles that might challenge the traditional use of the private office - from a more hierarchical environment to a more inclusive and flexible space that can encourage open dialogue and create a sense of equality. But, what might that look like for the future of private offices and workspaces in general? Hear more from Brian Graham on this new take on the private office. Watch here. Follow Doug on LinkedIn.Click here to get your copy of Doug's children's book—Design Your World.Follow Imagine a Place on LinkedIn.
Alison McConnell and Kerry Pollock are joined by Partick Thistle Women's coach Brian Graham as they discuss the weekend's Old Firm derby, which saw Celtic fans shut out of SWPL clash
It's Australia Day so Jane Lewis welcomes St Johnstone's Aussie defender Ryan McGowan onto the podcast along with Brian Graham – manager of Partick Thistle's women's team and striker for the Firhill outfit's men's side. They preview the weekend's fixtures including a make-or-break clash between Hearts and Aberdeen and discuss Steve Davis's retirement. Ryan fills us in on how the Scotland-based contingent are doing at the Asian Cup and Brian discusses leading his side to the SWPL Cup final.
Ben Haines and England Women's record goal scorer Ellen White are joined by Liverpool captain Taylor Hinds. The team reflect on the WSL weekend results, Liverpool's season so far and the psychology within the squad, plus Taylor's England aspirations. Partick Thistle manager Brian Graham also drops by to talk about his team who are part-time and have reached the SWPL Cup final, the first time in 53 years. Brian also plays for the men's side and discusses the dilemma he has with the women's final currently clashing with the men's match against Arbroath.Timecodes: 0:10 Intro 02:10 Lauren James show 06:20 More pressure on United 10:40 Arsenal 12:55 Brian Graham Partick Thistle 21:30 Liverpool season 29:40 Psychology sessions
Partick Thistle Women's manager and first-team striker Brian Graham joins the Women's Football Show this week to discuss what life is like as both player and manager. The Women's Football Show Highlights: 00:00 Intro - Partick Thistle WFC 01:14 Being a women's football coach 06:00 Women's Premier League results (SWPL) 08:55 Partick Thistle WFC training 11:31 Women's Soccer Coach 12:53 Women's football fixtures 17:48 Sky Sports Cup Quarter Finals 20:24 Pedro Martínez Losa interview 22:20 SWPL 1 professional teams Love Scottish women's football? Subscribe now @PLZSoccer #womensfootball #womenssoccer #football
Brian Graham Four Day Ray Brewery by The Donaide Podcast
We brought furniture designer Brian Graham back on the show for a laughter-filled and insightful bonus episode! Together we review a handful of powerful quotes from previous episodes."It's not your job's job to make you happy." —Cheryl Durst"If you are waiting for regulations to change the way we design it will be far too late." —Jane Hallinan"If everyone is doing neutral, then of course, we'll continue to do neutral, but who's going to be the brave one that steps out?" —Laura Guido Clark"If you're struggling with self worth, there have been more of us out there than you realize that have been very successful and had that exact same amount of self doubt." —Edward Wagoner"A single, full understanding of someone's complete experience and existence can generate so much inclusivity." —Angie LeeClick here to get your FREE copy of the Imagine a Place journalFollow Imagine a Place on LinkedInConnect with Doug Shapiro on LinkedIn
In today's episode, we welcome back Brian Graham, a fan favorite who always brings his unique blend of humor, thoughtfulness, and insight to our discussions.After our previous episode with Brian, we received an overwhelming response from listeners who wanted to hear more from him. So, we invited him back to chat about his recent trip to the IIDA Industry Roundtable in Santa Fe, New Mexico. Brian and Doug share their biggest takeaways from the event (including their take on the 2022 Oxford Dictionary word of the year....Goblin Mode).Join Doug and Brian as they explore the significance of placing trust in the universe, embracing risks as a designer, and the crucial role of robust leadership and mentorship in the design industry.Click here to get your FREE copy of the Imagine a Place journalFollow Imagine a Place on LinkedInConnect with Doug Shapiro on LinkedIn
Our first ever joint podcast! Today we're teaming up with Dr. Brian Graham, Superintendent of Grand Island Central School District and host of “Achieving Joy and Mastery in Public Schools” podcast and Rubie Harris, Assistant Superintendent for Business and Finance to discuss the importance of the Superintendent and SBO relationship. We also explore the transition back to normal operating budgets as the federal funds come to a close.
Designer. Advocate. Advisor. Humorist - Brian Graham's talent extends far beyond furniture design. For nearly 25 years, Brian has been turning out award-winning and internationally recognized work, but it's his ability to connect and communicate with people that just might be his greatest skill and a not-so-secret to success.In the wee hours before NeoCon, we sat down together in the OFS showroom to discuss what drives his creativity, how design is a "team sport," and the critical skills needed to be successful that might not be taught in design school. Click here to get your FREE copy of the Imagine a Place journalFollow Imagine a Place on Instagram: @imagineaplaceFollow Imagine a Place on LinkedIn
Taylor English's passion for disc golf has taken him around the world, from Halifax, Canada to Kurland, South Africa. Brian Graham is the Director of Membership and Growth for the PDGA. Together, they'll convince you that being bitten by the disc golf bug is a bite like no other.Follow IRB on InstagramShow notes and episode transcript at idratherbepodcast.com
Whichever stage of life you might be in, you'll want to live it to the fullest. You'll want mental clarity to perform at your best, energy to spend time with your loved ones, and a strong metabolism to maintain your ideal body weight. Using peptides is a great and effective way to remain healthy so you can make the most out of your life. In this episode, Brian Graham discusses the functions and benefits of different peptides. He also shares some exciting developments in the peptide space. Peptides come with amazing effects — but they can also come with unpleasant side effects when not used with caution. If you want to learn more about how peptides can power your body and enhance your quality of life, then this episode is for you! Here are three reasons why you should listen to the full episode: Learn how peptides work on your body. Discover the latest developments in the peptide space. Find out the numerous benefits of peptides. Get Customised Guidance for Your Genetic Make-Up For our epigenetics health programme, all about optimising your fitness, lifestyle, nutrition and mind performance to your particular genes, go to https://www.lisatamati.com/page/epigenetics-and-health-coaching/. Customised Online Coaching for Runners CUSTOMISED RUN COACHING PLANS — How to Run Faster, Be Stronger, Run Longer Without Burnout & Injuries Have you struggled to fit in training in your busy life? Maybe you don't know where to start, or perhaps you have done a few races but keep having motivation or injury troubles? Do you want to beat last year's time or finish at the front of the pack? Want to run your first 5-km or run a 100-miler? Do you want a holistic programme that is personalised & customised to your ability, goals, and lifestyle? Go to www.runninghotcoaching.com for our online run training coaching. Health Optimisation and Life Coaching Are you struggling with a health issue and need people who look outside the square and are connected to some of the greatest science and health minds in the world? Then reach out to us at support@lisatamati.com, we can jump on a call to see if we are a good fit for you. If you have a big challenge ahead, are dealing with adversity or want to take your performance to the next level and want to learn how to increase your mental toughness, emotional resilience, foundational health, and more, contact us at support@lisatamati.com. Order My Books My latest book Relentless chronicles the inspiring journey about how my mother and I defied the odds after an aneurysm left my mum Isobel with massive brain damage at age 74. The medical professionals told me there was absolutely no hope of any quality of life again. Still, I used every mindset tool, years of research and incredible tenacity to prove them wrong and bring my mother back to full health within three years. Get your copy here: https://shop.lisatamati.com/collections/books/products/relentless. For my other two best-selling books Running Hot and Running to Extremes, chronicling my ultrarunning adventures and expeditions all around the world, go to https://shop.lisatamati.com/collections/books. Lisa's Anti-Ageing and Longevity Supplements NMN: Nicotinamide Mononucleotide, an NAD+ precursor Feel Healthier and Younger* Researchers have found that Nicotinamide Adenine Dinucleotide or NAD+, a master regulator of metabolism and a molecule essential for the functionality of all human cells, is being dramatically decreased over time. What is NMN? NMN Bio offers a cutting edge Vitamin B3 derivative named NMN (beta Nicotinamide Mononucleotide) that can boost the levels of NAD+ in muscle tissue and liver. Take charge of your energy levels, focus, metabolism and overall health so you can live a happy, fulfilling life. Founded by scientists, NMN Bio offers supplements of the highest purity and rigorously tested by an independent, third-party lab. Start your cellular rejuvenation journey today. Support Your Healthy Ageing We offer powerful third-party tested NAD+ boosting supplements so you can start your healthy ageing journey today. Shop now: https://nmnbio.nz/collections/all NMN (beta Nicotinamide Mononucleotide) 250mg | 30 capsules NMN (beta Nicotinamide Mononucleotide) 500mg | 30 capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 250mg | 30 Capsules 6 Bottles | NMN (beta Nicotinamide Mononucleotide) 500mg | 30 Capsules Quality You Can Trust — NMN Our premium range of anti-ageing nutraceuticals (supplements that combine Mother Nature with cutting edge science) combats the effects of aging while designed to boost NAD+ levels. Manufactured in an ISO9001 certified facility Boost Your NAD+ Levels — Healthy Ageing: Redefined Cellular Health Energy & Focus Bone Density Skin Elasticity DNA Repair Cardiovascular Health Brain Health Metabolic Health My ‘Fierce' Sports Jewellery Collection For my gorgeous and inspiring sports jewellery collection, ‘Fierce', go to https://shop.lisatamati.com/collections/lisa-tamati-bespoke-jewellery-collection. Episode Highlights [04:20] Entering The Peptide Space Brian is a peptide specialist at Boulder Longevity Institute. When he first entered the peptide space, he worked more on performance optimization. He underwent educational training at the American Academy for Anti-Aging and Regenerative Medicine and earned a formal certification. He met Dr. Yurth while she was working at an orthopedic practice. They focused on bringing medical innovation to clinical relevance through collaboration. [06:48] What Are Peptides? Peptides have been around for some time, even in traditional medicine. They are naturally-occurring products that help regulate or stimulate a given process. For example, insulin is a peptide that regulates blood glucose to prevent neuropathic pain and other complications. Many things can be targeted on a cellular level with a given peptide. [09:07] Proteins vs. Peptides A protein that's a large peptide has more binding sites or activity. Smaller sequences of amino acids become more specific for a given cellular target. When chopped up, large proteins are basically made up of peptides. Many environmental factors inhibit your body's ability to make a given peptide, such as prioritization and accumulation of stressors. The aging process is associated with a decreased ability to make certain peptides. [12:05] BPC-157 BPC-157 is a gastric-derived peptide that naturally occurs in the digestive system and helps support the cells and makeup of the digestive system. It increases blood flow, thus helping modulate healing and recovery processes, especially in the musculoskeletal system. It also helps with neuron regeneration and improves the integrity of the blood-brain barrier. It's an F-actin sequestering peptide that dampens the effects of scarring. [17:00] What's Happening in the Peptide Space The peptide space is incredibly dynamic with lots of innovative research and people working hard to get it to clinical relevance. While much of it is on the bench, there are many strides in the peptide space. There are many factors affecting the accessibility of peptides, such as market exclusivity. [19:42] Increasing Accessibility Brian has been advocating and informing his patients of what's available to them and gives them access if possible. Peptides that are in clinical development and have gone through safety trials require an API. Unfortunately, there are still some inconsistencies in products with company pharmacies that they partner with. It's important to assess what's going to be effective for you. [23:24] SS-31 SS-31 is a mitochondrial peptide that has market exclusivity. It targets the inner mitochondrial membrane and buffers lipid peroxidation, improving the overall system. Brian and his team are working on enhancing its effects by adding other synergistic materials to it. [27:33] GHK-Cu GHK-Cu is widely known in the aesthetic space for collagen deposition and reduction of fine lines and wrinkles. Peptides should be used with caution because taking too much might compromise your health. It's also being used for postoperative recovery and it could potentially help reorient genetic issues and damage. [31:15] Ta1 Thymosin alpha 1 modulates the immune system. It protects immunocompromised people who are more vulnerable to viral bacteria. It's used for vaccines against viral hepatitis, certain types of cancer, and autoimmune diseases. Essentially, it helps with immunosurveillance by identifying foreign invaders, such as viruses and bacteria, and removing them. Though it has an incredible safety record, it's under scrutiny and there is limited access to it. [31:15] Semaglutide and GLP-RA Semaglutide and GLP-RA are synthetic peptides that regulate metabolism, increasing energy utilization and decreasing fat storage. It's commonly used for glucose control. It also regulates metabolic processes in the brain, potentially reversing cognitive issues. However, it might also lead to nausea, vomiting, distension, and other issues because it slows down stomach emptying. [43:42] MOD GRF 1-29 Overstimulation of CJC-1295, which upregulates growth hormones, can lead to a host of issues, such as fluid retention and neuropathic pain. MOD GRF 1-29 promotes more robust growth hormone production. Using growth hormone-stimulating hormones might cause dependence because it will shut down your ability to produce growth hormones. Abusing growth hormones can shut down your body's abilities. Growth hormones are released robustly at night and put you in a position to recover. [49:23] Other Peptides Brian is only familiar with Epithalamin with regards to pineal gland-derived peptides. Cerebral lysine supports the nervous system and can potentially treat Alzheimer's disease, brain injury, stroke, etc. MOTS-c is a mitochondrial-derived peptide that's associated with longevity. Humanin is used with MOTS-c, due to its synergistic effects, to encourage greater levels of mitochondria and metabolic flexibility. Metabolic flexibility translates to overall system integrity, resiliency, and performance. [57:24] Supersapiens Supersapiens sensors track glucose, ketones, and lactate in real-time. It helps enhance your performance and guides you in knowing what you need. It's best to seek guidance when you start getting into the peptide space so you'll be able to do things effectively and safely. 7 Powerful Quotes “... essentially, what it does is it helps to regulate a given process. And that's what peptides do, they are essentially a key to a door or an opportunity to either lock a door of a given process or open it up…” “[Peptides] could be analogous to a dimmer switch on the wall: you're turning up the light or turning down the light, but that's going to correspond with the given physiologic mechanism.” “Just because this stuff looks good on paper doesn't necessarily mean it's going to be good for everyone. It's really important to distil down what is going to be effective for you so you're not wasting your time and your money doing a treatment that you don't necessarily need.” “If you're in a chronic deteriorative state where your body's sort of ill-equipped to address that need, then you're going to chronically upregulate inflammation and essentially chronically deteriorate, unfortunately.” “More is not always better.” “Everything happens in a rhythm. Everything has its own clock.” “It's important [...] to have guidance, whether that's with me or someone else that is skilled and understands this constantly evolving field to really do things effectively.” Resources Gain exclusive access and bonuses to Pushing the Limits Podcast by becoming a patron! Peptide Therapy and Caring for Our Cells with Dr William Seeds Supersapiens Biosensors Connect with Brian: LinkedIn About Brian Brian Graham is the Program Director at Boulder Longevity Institute. He's a certified peptide specialist through the International Peptide Society and American Academy for Anti-Aging and Regenerative Medicine. Brian is an industrious health and wellness professional with a thorough understanding of clinical peptide modalities. Through his work, he provides high-level concierge health services to patients and is well-versed in peptide sales. If you want to know more about Brian, you can connect with him on LinkedIn. Enjoyed This Podcast? If you did, be sure to subscribe and share it with your friends! Post a review and share it! If you enjoyed tuning in, then leave us a review. You can also share this with your family and friends so they can know how to optimise sleep. Have any questions? You can contact me through email (support@lisatamati.com) or find me on Facebook, Twitter, Instagram, and YouTube. For more episode updates, visit my website. You may also tune in on Apple Podcasts. To pushing the limits, Lisa