Podcasts about world first

Professor Aideen Ryan, Professor in Tumour Immunology at University of Galway's College of Medicine, Nursing and Health Sciences. Photo: Andrew Downes Researchers at the University of Galway have revealed the results of a world-first study into how bowel cancer shuts down the immune system, and how this can be reversed to improve treatment. The findings have been published in the Journal for ImmunoTherapy of Cancer (JITC). Breakthrough for bowel cancer immunotherapy The research team showed how structural stromal cells switch off the immune system and how the body's own killer cells can be switched back on, opening up the opportunity for a completely new approach to optimising immunotherapy for patients. Colorectal cancer - commonly referred to as bowel cancer - is one of the world's most common cancers and the second leading cause of cancer death worldwide. Diagnoses in people under 50 have been climbing in recent decades, with recent global analysis showing these early-onset cases have almost doubled since 1990. In Ireland, the disease affects more than 2,500 people a year. Professor Aideen Ryan, Professor in Tumour Immunology at University of Galway's College of Medicine, Nursing and Health Sciences, said: "While immunotherapy has revolutionised care in cancers such as melanoma and lung cancer, it has shown very limited benefit in bowel cancer, leaving patients with advanced disease with few treatment options and poor survival outcomes." The breakthrough research discovery is the first to demonstrate that tumour stromal cells - the structural cells that support cancer growth - are directly reprogramming the immune system. They do this by switching off, or hijacking, two of our body's most important tumour-fighting cells - the natural killers (NK) and macrophages - rendering them unable to attack the cancer. Professor Ryan said: "The interaction between the cancer, our body's healthy cells and our defence mechanism is a complex one, but our research shows that the cancer is essentially creating an immune brake - it is blocking the body's natural response and fight mechanism." What has been discovered in relation to how the cancer interacts with the human body? Tumour stromal cells are the structural cells which allow the cancer to grow. They are coated in sugars called sialoglycans. These interact with receptors on the body's immune cells called Siglecs. This interaction causes the body's natural defence response to be switched off and unresponsive when immunotherapy is used, and therefore unable to attack the cancer. The research identified a specific enzyme that drives this process of 'switching off', as it produces the Siglec-binding sugars on stromal cells. When the researchers blocked this pathway using drugs called sialidases, they could show that the body's most important tumour-fighting cells - the natural killers (NK) and macrophages - reactivated. It showed that the tumours shrank and the spread of cancer, known as metastasis, was prevented. The multidisciplinary research was conducted in collaboration with colorectal surgeons and pathologists at Galway University Hospital, led by Professor Aisling Hogan and Professor Sean Hynes; as well as experts in colorectal cancer - Dr Philip Dunne, Queen's University Belfast and experts in targeting sialoglycans at Palleon Pharmaceuticals, MA, USA, who have developed sialidase drugs that disrupt the sialoglycan-Siglec interaction. Professor Ryan added: "Our research is a clear breakthrough in our understanding of bowel cancer and how immunotherapy could be more successful. This world-first finding shows that some of the bowel cancer cells are not just passive bystanders, they are actively reprogramming the body's immune cells, preventing them from doing their job. We have uncovered an entirely new checkpoint and by focusing on it we can reactivate the immune system and improve our body's innate ability to fight the disease, and even target metastasis." Michael O'Dwyer, Pro...

Hello folks, we're back once again. This time Maximum & Dorki are joined by the legendary Meeres while Dratnos is locked away in a cellar somewhere. Meeres is here to give us some great insight on the future of WoW and his opinions on the upcoming changes to midnight. Hope you enjoy!For Business Inquiries:Poddymanagement@gmail.com

Thursday Headlines: Israel says one of four bodies handed over by Hamas is not a hostage, three Australian men accused of Bali villa shooting could face the death penalty, the world’s carbon dioxide levels have reached record highs, NRL players now face 10-year ban for joining rival competition, and Virgin Australia’s pets on flights trial is underway! Deep Dive: New research has revealed the worst offenders for image-based sexual abuse in Australia, including those who create deepfakes and revenge porn, or take photos and videos without consent. The Australian Institute of Criminology says such crimes are disproportionately carried out by young men, while the type of offending differs across age groups and genders. In this episode of The Briefing, Tara Cassidy speaks with AIC research manager Tom Sullivan about what's needed to address the growing problem, and how tech advancements are making it harder to stop. Follow The Briefing: TikTok: @thebriefingpodInstagram: @thebriefingpodcast YouTube: @TheBriefingPodcastFacebook: @LiSTNR Newsroom See omnystudio.com/listener for privacy information.

Hospice New Zealand have launched a world-first project inviting people who are dying and their caregivers to review the everyday services around them. Hospice NZ Chief Executive Wayne Naylor spoke to Ingrid Hipkiss.

In La Chaux-de-Fonds, Switzerland, recycling just got a major upgrade

Ever wondered what it really costs to turn a light-bulb moment into something real? This week’s Money Diarist is a mum of two who did exactly that. She created a world-first product that launched just two weeks ago, and now she’s here to do what most founders wouldn’t: spill on every dollar it took to make it happen. From losing out to a dodgy sourcing agency to somehow pulling together $200K through pure determination, she’s laying it all out... the risks and the real-world chaos of betting on yourself. Inside the ep, we what it actual costs to get a product made, and how she’s juggling start-up life, toddler meltdowns, and a mortgage. It’s messy, bold, and so unbelievably relatable. GET VICTORIA'S BUDGETING SYSTEM: Master your cashflow here.Ready to binge more relatable, inspiring, and downright juicy money stories? Check out our ultimate Money Diaries playlist. Listen now Join our Facebook Group AKA the ultimate support network for money advice and inspiration. Ask questions, share tips, and celebrate your wins with a like-minded crew of 300,000+. And follow us on Instagram for Q&As, bite-sized tips, daily money inspo... and relatable money memes that just get you. Acknowledgement of Country By Nartarsha Bamblett aka Queen Acknowledgements. The advice shared on She's On The Money is general in nature and does not consider your individual circumstances. She's On The Money exists purely for educational purposes and should not be relied upon to make an investment or financial decision. If you do choose to buy a financial product, read the PDS, TMD and obtain appropriate financial advice tailored towards your needs. Victoria Devine and She's On The Money are authorised representatives of Money Sherpa PTY LTD ABN - 321649 27708, AFSL - 4See omnystudio.com/listener for privacy information.

If you are a Disney World newbie, don't make these mistakes! Today I'll share 10 problems new Walt Disney World guests tend to have, and how you can avoid them. Follow along for my favorite Walt Disney World tips, and don't miss future episodes for those new to Walt Disney World. I hope you enjoyed today's show. I'd love to connect with you over on Instagram @mountains_of_magic or Facebook at Fantastical Vacations by Daniele. If you would like help in planning an upcoming Disney or Universal vacation, email me at danielerobbins@fantasticalvacations.com or fill out a quote form to get started planning the magic Get A Quote Want the latest travel deals and all my tips for Disney, Universal and Cruising?Join my email newsletter  Want to try fetch rewards and get free gift cards by scanning receipts? Use my code 8G48W to get 2000 points at sign up. FETCH REWARDSMy Website mountainsofmagic.square.siteMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/andrey-rossi/bring-the-funLicense code: E9BZCTS1O3JRPERX This podcast is not sponsored or supported by Fetch Rewards. Views of the host are her own. 

New Zealanders will be part of a world-first clinical trial into how to treat a dangerous condition that causes heart attacks in young women - including new mothers. Grant recipient and senior researcher, Caroline Alsweiler spoke to Corin Dann.

Your morning briefing, the business news you need in just 15 minutes. On today's podcast: (1) HSBC Holdings said it’s achieved a world-first breakthrough in deploying quantum computing in financial markets, as a race intensifies among some of Wall Street’s biggest firms to embed the cutting-edge technology in their daily operations. (2) Intel has approached Apple about securing an investment in the ailing chipmaker, according to people familiar with the matter, part of efforts to bolster a business that’s now partially owned by the US government. (3) US stocks are screamingly expensive when viewed from a historical perspective. But dig into the details, and the sky-high valuations may well be warranted, say strategists at Bank of America (4) The US lowered tariffs on auto imports from the European Union to 15% retroactive to Aug. 1, cementing terms of the framework trade agreement the two sides struck almost two months ago (5) Splits on the Bank of England policymaking committee were on full display on Wednesday after Governor Andrew Bailey said there was further to go on interest-rate cuts just hours before external member Megan Greene proposed “skipping” a cut in November. (6) Russia plans to run a budget deficit for a fifth year as declining revenue and increased spending continue to put pressure on the government’s finances amid the Kremlin’s war on Ukraine. (7) Global drugmakers including Merck, Eli Lilly and AstraZeneca are pausing or canceling investments in the UK while throwing barbs at the lack of competitiveness of its business environment Podcast Conversation: Bob Iger Just Learned a Hard Lesson: Beth KowittSee omnystudio.com/listener for privacy information.

This episode of the OnBase Podcast features a compelling discussion with Nick Webb on the power of a modern go-to-market strategy. Host Paul Gibson and Nick explore the challenges of navigating organizational change and the critical shift from high-volume, low-quality lead generation to a targeted ABM/ABX approach. Nick shares the story of how CloudPay transformed its pipeline by moving from "net fishing" to "spear fishing," a move that quadrupled its sales pipeline.The conversation reveals why sales and marketing alignment is non-negotiable and how data-driven decisions provide the confidence needed to make bold changes. Nick details the hurdles, the mindset shifts, and the specific KPIs that were essential to driving this monumental transformation. This episode is a masterclass for any B2B leader looking to build a scalable and effective growth engine.Key TakeawaysQuality Over QuantityGenerating thousands of leads is meaningless if it doesn't translate to pipeline. Focusing on an agreed-upon ICP is the foundation of a successful GTM strategy.Shared KPIs Drive AlignmentShifting marketing's core KPI from lead volume to dollar-value pipeline ensures both sales and marketing are working toward the same goal.Data is Your Ally in ChangeUse data to prove the need for change and validate new strategies. Data-backed insights overcome resistance and build trust across teamsIt's a Partnership Not a HandoffThe old model of marketing throwing leads over the fence is broken. A modern GTM requires genuine collaboration where sales and marketing are fully integrated.Rethink Your TerminologyCalling leads "signals" reframes the follow-up process, shifting focus from pursuing an individual to understanding account-level interest.Quotes"Gone are the days where marketing people could get away with not knowing their numbers. We have to carry a number just like sales people do."Best Moments (07:22) – The Damascene Moment Nick details the realization that generating 3x more leads was actually causing the sales pipeline to fall.(09:38) – From Net Fishing to Spear Fishing The core analogy that drove CloudPay's strategic shift to a targeted ABM/ABX model.(14:25) – The New Playbook How CloudPay revolutionized its operations by changing KPIs, moving BDRs into marketing, and renaming leads to "signals."(20:00) – Overcoming Resistance Nick outlines the three groups of people in any change scenario and how to build momentum with advocates and data.(33:27) – Stopping the Attribution Wars The decision to stop attributing leads to specific departments and why it immediately ended internal friction.Shout-OutsKate Cox - CEO, Bray Leino.Tim Johnson - Field CTO, Gaming, Databricks.Andy McFarlane - VP of Marketing, Morse Micro.About the GuestNick Webb has more than 25 years of Marketing experience in world-class technology and fintech organisations, including Vodafone, Microsoft and WorldFirst. Now, as Chief Marketing Officer of CloudPay, Nick leads the Marketing team to build market awareness and drive business growth through the creation of a pipeline of leads and prospects for the Sales teams.Connect with Nick.

AuxBrief to launch world-first digital legal brief in SA by Radio Islam

Shesha, a world-first beverage created by SA Canegrowers and produced in Zinkwazi, is a refreshing, natural drink with a unique boost, proudly owned by sugarcane growers. It supports over 65,000 jobs and 1 million livelihoods in rural KZN and Mpumalanga, symbolizing local empowerment and innovation. Radio Life & Style on Facebook · The Morning Show Sponsor: Excellerate Security

Indonesian student has developed an interactive online map that accurately measures soil moisture levels at very high resolution, almost in real time. - Mahasiswa asal Indonesia berhasil mengembangkan peta daring interaktif yang mengukur tingkat kelembapan tanah secara akurat dengan resolusi sangat tinggi, hampir dalam waktu nyata.

Tuesday Headlines: Aussie kids will be banned from having violent, harmful and sexual conversations with AI chatbots, Victorian Premier’s orders crisis talks with a South Sudanese community after double stabbing, man accused of trying to assassinate Donald Trump faces trial, search for Dezi Freeman enters third week as officer laid to rest, and Mary Fowler hits the catwalk. Deep Dive: After nearly four years on the run, New Zealand fugitive Tom Phillips was shot dead following an armed standoff with police on Monday. Phillips had been in hiding with his three children since 2021, prompting one of the country’s most high-profile missing persons investigations. In this episode of The Briefing, Natarsha Belling speaks with private investigator Chris Budge about the final moments of Tom Phillips’ life, the years he spent in hiding, and what the future holds for the children at the centre of it all. Follow The Briefing: TikTok: @thebriefingpodInstagram: @thebriefingpodcast YouTube: @LiSTNRnewsroom Facebook: @LiSTNR NewsroomSee omnystudio.com/listener for privacy information.

Gulvan and Joe discuss Race for World First and the War Within, Layoffs at Firaxis and Dreamhaven, Helldivers Crossover and AI in Roblox. Continue reading →

Hello friends and enemies of the PoddyC Podcast. In this weeks episode we are talking about Liquid Sweeping the war within, boss tuning, everything that's happened since 11.2 came out, and so many more things it's kinda crazy. This episode is stacked and you better enjoy it.For Business Inquiries: Poddymanagement@gmail.com

This week our host is our special guest, Liz Patt, who has a lot of opinions on Diablo, but she's also here for a discussion of patch 11.2. The team love Tazavesh, 10/10 city, no notes, though they remain a little skeptical of Broker culinary pursuits. We also looked at the Race to World First, which is underway as raid guilds contend to see who can get the first Mythic kill of Dimensius. Plus, General Manager Rod Fergusson has left Diablo, and we aren't quite sure what that means for the series. And in a segue which is no way jarring, we turn from Diablo to the Wholesome Games Festival on Steam, and some of the cute and cozy titles we enjoyed from that showcase.If you have a few minutes, please fill out our survey to tell us what you think about the podcast. This data is collected by our podcast host, Acast, and will be used to help us improve the show as well as attract potential sponsors. Your answers are completely anonymous. We appreciate your help!If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.

Sean, Lex, and Manny discuss the official reveal of Legion Remix, the slow start to Manaforge: Omega's Race to World First, and the wealth of content coming in the World of Warcraft.

Hello friends and enemies of the PoddyC Podcast. In this weeks episode we are discussing all things Race to World First, 11.2 being launched and a bunch of Drama - because that's important! hope you enjoy!For Business Inquiries:Poddymanagement@gmail.com

Smartphones are out and cameras are in - at least, that's our verdict for this early World Photography Day special episode! We're joined by camera fanatics and experts this week to discuss the biggest headlines from 2025, including recent developments from Insta360 and DJI that sees the two brands crossing party lines into each others markets. From unique mirrorless cameras like the Sigma BF to the nostalgic Fujifilm Instax Wide Evo, we've got plenty of snappers to chat about.Join Josephine Watson, Hamish Hector and Lance Ulanoff as well as special guests Tim Coleman and Amelia Schwanke as we talk about the latest and greatest in tech - and yep, that includes more AI antics.

A world-first m-R-N-A vaccine has been developed to protect cattle from foot and mouth disease. An outbreak on the disease would devastate cattle production and trade and wipe an estimated 80 billion dollars from the economy. Rural Reporter Katie Fuller spoke with Meat and Livestock Australia's animal wellbeing program manager Michael Lawrence about the research program.See omnystudio.com/listener for privacy information.

Cory joined us for this week's show, and by coincidence there was also a Heroes of the Storm patch the day they recorded. What are the odds? Not very good, if you ask Cory. There was also a new Hearthstone Battlegrounds season to discuss. We're all very much looking forward to next week, when patch 11.2 finally releases, and we learn more about what Xal'atath has cooking. The Race for World First also already has our attention. We'll miss Void Storage, though.Plus, this week we had a lot of time for listener questions, so don't forget to send those in. Sometimes we have a ton going on so we don't get to them, but they're always fun to answer. You can address them to podcast@blizzardwatch.com or ask them in the #queue-and-podcast-questions channel on our Discord server.If you have a few minutes, please fill out our survey to tell us what you think about the podcast. This data is collected by our podcast host, Acast, and will be used to help us improve the show as well as attract potential sponsors. Your answers are completely anonymous. We appreciate your help!If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.

The government has stepped up its crackdown on anyone involved in assisting illegal migration in the UK. Foreign secretary David Lammy described the new sanctions, which will be implemented tomorrow, as ‘world first' measures to tackle people smuggling. The Standard's Chief Political Correspondent Rachael Burford joins us with the latest. And in part two, John Darlington, director of the World Monuments Fund, explores the history of the Ragged School Museum in the capital's East End, which is this week's Hidden London feature. Hosted on Acast. See acast.com/privacy for more information.

Scientists are unveiling a world-first mobile greenhouse gas lab to gather data for the country to meet its net-zero climate targets. GNS Principal Scientist and CarbonWatch-Urban Programme Lead Dr Jocelyn Turnbull spoke to Ingrid Hipkiss.

It's been said that First John "is a masterpiece in the art of edification" (George Findley, 1909).In this series, we will see how the Apostle John exhibits tender, pastoral care as he calls the church back to the three basics of Christian life: true doctrine, obedient living, and fervent devotion.This week's message, OVERCOMING THE WORLD, comes out of 1 JOHN 5:1-5.Website: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.rittmangrace.org⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Rittman Grace Brethren Church⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠rittmangrace⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠RittmanGrace⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠YouTube: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCaXPiaa4z3iZMA4DkCihtHg⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠rittmangbc⁠

Afternoon Headlines: Iran's supreme leader vowed to show “no mercy”, third Australian arrested in Bali over the alleged targeted shooting of two Melbourne men and Optus facing $100 million fine for inappropriate sales practices and misconduct Deep Dive: Lifeblood has announced a major overhaul of restrictions that prevent gay and bisexual men and transgender women from donating plasma and blood. It will allow an estimated 600,000 thousand more Australians to help save and change lives through generous donations. In this episode of The Briefing Natarsha Belling is joined by Member for Sydney MP Alex Greenwich and blood donation advocate Kate Fisher from Milkshakes for Marleigh to unpack these new changes and the difference they will make for millions of Australians. Follow The Briefing: TikTok: @listnrnewsroom Instagram: @listnrnewsroom @thebriefingpodcast YouTube: @LiSTNRnewsroom Facebook: @LiSTNR NewsroomSee omnystudio.com/listener for privacy information.

Mario Kart World kicks off a new era for both Nintendo and the DKU, but does it also kick ass? Hyle and Dustin go on a rambling Free Roam discussion about the big launch title, with a special emphasis (as always) on Donkey Kong!

Join global leaders in investment migration—Bob Kraft, Dan Wycklendt, Aaron Grau, and Bruno L'ecuyer— in our next episode of the Investing in the American Dream Podcast, as they unpack the future of the EB-5 program and international trends in the post-RIA era. Gain valuable insights into rural visa set-asides, key legislative updates, and project success stories like KAIA, which recently received its first I-526E approval in just six months.IMC: https://investmentmigration.org/IIUSA: https://iiusa.org/FPP: https://www.firstpathway.com/

After a long and turbulent road to get here, Nintendo's latest console is finally here! We talk about our first impressions for the Nintendo Switch 2, how picking it up went, our thoughts on the screen, how the Joy-Con 2's feel, express disappointment in the eShop being a disaster still, what we think of Mario Kart World, and some of of the performance boosts from other games, and our thoughts on the next big game to come! Come and hang out with us and let us know your thoughts for the Nintendo Switch successor so far! Don't forget - Middle-Earth: The Podcast, a new show featuring Andy, Al, and Corey as they talk about the books, movies, games, and everything in-between relating to J.R.R. Tolkien's incredible legendarium! Catch the first episode when it drops later this month on Patreon.com/SPNet!   Visit OmegaMetroid.com!   Subscribe! Podbean x iTunes x Spotify x YouTube Support us on Patreon! Omega Metroid Patreon Buy Omega Metroid Merch! Check out our Etsy merch shop! Download the Omega Metroid Theme Song! Get the Single for Free on Bandcamp! Follow us! @OmegaMetroid x @Spiteri316 x @DoominalCross x Omega Metroid Team Member Starter Pack Chat with us in Discord! Omega Metroid Discord Advertise on the Omega Metroid Podcast!

Interesting news coming out of China's Ant International, a global digital payments and fin tech provider. They have launched a new AI play with Alipay+ GenAI Cockpit. This will be an AI-as-a-Service (AIaaS) platform. The strategy is to support fintech companies and nudge super apps to build AI driven financial services with the goal of better security, flexibility and seamless experiences. Making AI work for finance remains the key goal for fin tech companies. Alipay+ GenAI Cockpit is a platform to help entrepreneurs create effective AI-native financial services. These tools will combine automated workflows and task orchestration with a dynamic enterprise context. Key tasks include payment orchestration, customer onboarding, compliance checks, fraud detection, dispute resolution, and evaluation and performance optimisation. New AI Platform for Fintechs launched by Ant International Three-pronged AI strategy focuses on AI security, Vertical Fintech Expertise, and Full-stack AI platform support First fintech clients begin official integration in June 2025 in Southeast Asia and South Asia "The future of finance will be shaped by agentic AI that not only carry out tasks autonomously in real automated workflows and sophisticated financial business and compliance context with reliability, but also interact, evolve and learn rapidly in orchestration with ever-growing precision," said Jiangming Yang, Chief Innovation Officer of Ant International. Alipay+ GenAI Cockpit has been honed on Ant International's four key business units: wallet gateway service (Alipay+), merchant payment service (Antom), cross-border business account service (WorldFirst), and embedded finance service (global treasury management, digital lending and credit tech solutions). Upon successful completion of trial runs, the first external clients in Southeast Asia and South Asia will start officially deploying the Cockpit in June 2025. Three-Pronged AI Strategy: Security, Vertical Fintech Expertise, and Platform-level Support for Agentic FinAI Combining a fintech-specific toolbox and dynamic industry knowledge base alongside business-ready AI innovations, the Cockpit embodies three key directions of Ant International's AI strategy. Security Shield for Trusted AI AI scamming threats using deepfake and other technologies have been growing over 10 folds by the year, with grave implications especially in the financial sector. Statistics show 22% of businesses have encountered AI-generated payment fraud. Ant International invests heavily in AI security solutions to combat external AI scamming attacks and eliminate internal model security risks such as model hallucination or bias. Its AI SHIELD framework manages risks across system architecture designing, data processing, model training, and inferencing. It offers real-time dynamic risk assessment, including detecting adversarial prompts and sensitive data leakage through over 100 recognition models and 600,000 risk lexicons. Today, fraud loss rate in Ant International's merchant payment service is 5% of industry average. Deep Vertical Financial Expertise Alipay+ GenAI Cockpit leverages over 20 leading LLMs, including Ant International's own Falcon Time-Series Transformer FX Model. However, it has focused on integrating fintech knowledge bases, such as bank transfer rules and dispute resolution policies, to help businesses build specialized fintech agents. The Cockpit toolbox supports retrieval-augmented generation (RAG), post-training, evaluation, and benchmarking, taking the combination of general-purpose datasets with industry-specific benchmarks developed from Ant International's financial expertise to help improve model precision. Built on the Cockpit, Antom Copilot is the world's first AI agent designed to help merchants boost conversion by streamlining the process of payment method integration, recommending optimal payment channels, and resolving common tasks like code correction and the auto-completion of merc...

In a world first, Stacey Wales used AI to bring her brother back to life so he could face his killer and deliver his own victim impact statement from beyond the grave. In this powerful episode, Stacey shares the emotional journey behind that decision and what it meant to give her brother a voice one last time. Xanthe and Tim also speak with Duke Law Professor Paul Grimm, who unpacks the ethical and legal implications. Together, they explore how grief, justice and technology are colliding in ways we've never seen before. Watch the AI victim impact statement HERE. Watch the judge's reaction HERE.See omnystudio.com/listener for privacy information.

This one's a conversation with a new friend. My guest hails from Florida, USA, and this is probably the beginning of a sequence of chats I'd like to have with him.Our focus was on what my guest calls, "world first" play and we specifically take his currently running Twilight 2000 campaign as an example. Yes, we talk GURPS and we talk modern post-apoc but that's not quite the point: this is about methodology.Big thanks up front to Patrick for coming to talk!Game on!Pat's T2K blog: t2kcampaigns.comRoleplay Rescue Details:Voice Message:speakpipe.com/roleplayrescuePatreon:patreon.com/rpgrescue Email:roleplayrescue@pm.meBlogroleplayrescue.com Bluesky Social:https://bsky.app/profile/ubiquitousrat.bsky.socialMeWe:https://mewe.com/p/roleplayrescueLogo and artwork by MJ Hiblen:https://www.patreon.com/MJHiblenART/ Hosted on Acast. See acast.com/privacy for more information.

This one's a conversation with a new friend. My guest hails from Florida, USA, and this is probably the beginning of a sequence of chats I'd like to have with him.Our focus was on what my guest calls, "world first" play and we specifically take his currently running Twilight 2000 campaign as an example. Yes, we talk GURPS and we talk modern post-apoc but that's not quite the point: this is about methodology.Big thanks up front to Patrick for coming to talk!Game on!Pat's T2K blog: t2kcampaigns.comRoleplay Rescue Details:Voice Message:speakpipe.com/roleplayrescuePatreon:patreon.com/rpgrescue Email:roleplayrescue@pm.meBlogroleplayrescue.com Bluesky Social:https://bsky.app/profile/ubiquitousrat.bsky.socialMeWe:https://mewe.com/p/roleplayrescueLogo and artwork by MJ Hiblen:https://www.patreon.com/MJHiblenART/ Hosted on Acast. See acast.com/privacy for more information.

In this edition of Willie's World, Willie P talks about Charlotte FC surging to the top of the Eastern Conference table, after a dominant home win last weekend, he tells you what he wants the Panthers to do tomorrow night in the NFL Draft, and hands out his Swine of the Week award See omnystudio.com/listener for privacy information.

It's been a very exciting week for squid expert Dr Kat Bolstad, who was called on to verify the sighting of a baby colossal squid in its natural habitat hundreds of metres under the sea.

Feel yourself getting sick at Disney World? I hope not, but if you find yourself under the weather at the most Magical Place on Earth, here are the things you'll want to know. First and foremost ask for help, but this episode has other resources and tips for your if you find yourself ill. Join my email newsletterI hope you enjoyed today's show. I'd love to connect with you over on Instagram @mountains_of_magic or Facebook at Fantastical Vacations by Daniele. If you would like help in planning an upcoming Disney or Universal vacation, email me at danielerobbins@fantasticalvacations.com or fill out a quote form to get started planning the magic Get A Quote Want to try fetch rewards and get free gift cards by scanning receipts? Use my code 8G48W to get 2000 points at sign up. FETCH REWARDSMy Website mountainsofmagic.square.siteMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/andrey-rossi/bring-the-funLicense code: E9BZCTS1O3JRPERX This podcast is not sponsored or supported by Fetch Rewards. Views of the host are her own. 

IN THIS EPISODE WE (MAX) WON THE RACE TO WORLD FIRST AGAIN WOOO!!!we also discuss the general state of the tier, how the raid is and many more things - hope you enjoy!For business inquiries: Poddymanagement@gmail.com

It probably isn't a huge surprise that our hottest topic this week was the World of Warcraft player housing preview. We also discussed how the Race to World First played out, and how this Race differed from past races. Plus, WoW Classic is getting its own new content in the form of the Scarlet Enclave, which seems cool -- if a little outside the scope of what you'd think for WoW Classic. And since Cory joined us this week, we got a healthy dose of copium as always with Warcraft Rumble updates and Heroes of the Storm, uh, news.If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.

Sean is sick but the show must go on! Lex and Manny discuss 11.1 in the aftermath of the Race to World First, more Delve and Brann tuning changes, and if the end game is heading in a healthy direction.

Garda numbers - crime writer Paul Williams has no doubt about who's to blame....Would you discipline someone else's child - when is it appropriate - or is it ever... Dulcie is a first - not in Cork, not in Ireland - in history…& lots more Hosted on Acast. See acast.com/privacy for more information.

We're experimenting and would love to hear from you!In this episode of 'Discover Daily', we explore a groundbreaking medical achievement: an Australian man who survived 100 days with a BiVACOR titanium heart before successfully receiving a donor heart transplant. This world-first procedure marks a significant milestone in artificial heart technology, potentially revolutionizing treatment options for millions of heart failure patients globally. The BiVACOR device, featuring magnetic levitation technology and a single moving part, represents a major advancement in addressing the critical shortage of donor hearts.We also examine Meta's upcoming launch of Community Notes across Facebook, Instagram, and Threads—a crowd-sourced content moderation system designed to replace third-party fact-checking with a less biased approach to information quality. The feature will enter public beta on March 18, 2025, with Meta building upon X's open-source algorithm while implementing careful monitoring systems during the initial rollout phase.Additionally, we discuss Anthropic CEO Dario Amodei's thought-provoking proposal to give AI models an "I quit this job" button, raising profound questions about AI autonomy, ethics, and potential machine consciousness. This controversial idea suggests implementing a preference framework that would allow advanced AI systems to opt out of tasks they find unpleasant, challenging traditional views of AI as mere tools without agency and potentially necessitating a reevaluation of how we treat these increasingly sophisticated systems.From Perplexity's Discover Feed:https://www.perplexity.ai/page/meta-launching-community-notes-zW.K9fx0S9eAcLwAin8LXw https://www.perplexity.ai/page/anthropic-ceo-floats-ai-quit-b-BotCYKfST6GePBfE_Psp6whttps://www.perplexity.ai/page/man-survives-with-titanium-hea-y6lkRQKXSNyztF.8dQL1uQ**Introducing Perplexity Deep Research:**https://www.perplexity.ai/hub/blog/introducing-perplexity-deep-research Perplexity is the fastest and most powerful way to search the web. Perplexity crawls the web and curates the most relevant and up-to-date sources (from academic papers to Reddit threads) to create the perfect response to any question or topic you're interested in. Take the world's knowledge with you anywhere. Available on iOS and Android Join our growing Discord community for the latest updates and exclusive content. Follow us on: Instagram Threads X (Twitter) YouTube Linkedin

Joe started off the podcast this week eating crow as he reflected on his prior assertion that BlizzCon would never happen again. But, Blizzard announced that BlizzCon returns September 12-13 2026. He's not mad at all, just surprised -- as all our hosts were.After that, it's a little tough to focus on everything else that happened this week. The Race to World First is still on in Liberation of Undermine, Brann getting a nerf in Delves -- but, come on, BlizzCon! The chat about Diablo 4's announced difficulty boost to Torment brought us back into gory reality a bit.Plus, we discuss the BAFTAs survey on the most influential game of all time, and what our picks might be. Hosted on Acast. See acast.com/privacy for more information.

Afternoon headlines: Former Australian cricketing great Stuart MacGill found guilty over facilitating a cocaine deal, power bills to increase again and an American influencer's visa under review after a disturbing online video Deep dive: Hear from the Australian professor who was part of the team behind a world first that is set to revolutionise how we treat heart failure and transplants. Professor Chris Hayward gives the inside story into how an Australian man became the first person in the world to be discharged from hospital with a high-tech titanium artificial heart. In this episode of The Briefing Natarsha Belling is joined by Professor Hayward, a cardiologist at St Vincent's Hospital Sydney, to explain why this major breakthrough is being hailed around the world. Follow The Briefing: TikTok: @listnrnewsroom Instagram: @listnrnewsroom @thebriefingpodcast YouTube: @LiSTNRnewsroom Facebook: @LiSTNR NewsroomSee omnystudio.com/listener for privacy information.

Should celebrities watch what they say? The latest controversy has come out after Emilia Perez was torpedoed by a castmember's comments. And why not hold them to the same standards most of us are?Urban Dead, one of the longest running zombie MMOs, is being shut down due to the new Online Safety Act in the UK. While it's sad to see something with such a cult following go, you can't run a product like that without the right loicence mate.The first computer made with human brain neurons has been created. Let's hope they can't feel pain.We're supported by Rez. Get 15% off with code “NERDS15” at www.drinkrez.com Scrub your history– Following 'Emilia Pérez' Oscar Controversy, Hollywood Reportedly Moves To Make Social Media Scrubbing "An Essential Component" Of Every Awards Campaign Urban dead vs UK government – Free-to-play browser game Urban Dead taken offline by UK's online safety law Bio computer made of brain cells now in Melbourne – Melbourne start-up launches 'biological computer' made of human brain cells - ABC News Full Show Notes : https://docs.google.com/document/d/1B-vX370-LB9fJ5kVsPcXlNkoe_g5tq5XlFdnMF46nmQ/edit?usp=sharing Follow us onFacebook Page - https://www.facebook.com/NerdsAmalgamated/Twitter - https://twitter.com/NAmalgamatedSpotify - https://open.spotify.com/show/6Nux69rftdBeeEXwD8GXrSiTunes - https://itunes.apple.com/au/podcast/top-shelf-nerds/id1347661094Instagram - https://www.instagram.com/nerds_amalgamated/Youtube - https://www.youtube.com/@nerdsamalgamatedTikTok - https://www.tiktok.com/@nerdsamalgamated Hosted on Acast. See acast.com/privacy for more information.

An inside look into how the iconic hit, “We are the World,” came to be. Also, new details on groundbreaking research that's being done to help find cancer before it spreads. And, Regé-Jean Page talks being a secret agent in his new thriller, “Black Bag.” 

This week's show started off with The War Within season 2. We discussed how we feel about Undermine now that we've had a week in the zone, though Liz noted the patch added a ton to do outside the zone, too. All the co-hosts are now on the record as emphatically pro jazz, and also pro Race to World First, which officially kicked off as the season did. Diablo events and why they're too short (maybe to even bother with them at all) were a hot topic this week, with the week-long Gilded Goblins event going on now, but blink and you've probably already missed it.Also, some of us are really pumped for the Visual Novel Fest on Steam this week. Guest host Phil Ulrich named off some of his favorites, which led Liz down a rabbit hole. Everything from Hatoful Boyfriend to Coffee Talk to Boyfriend Dungeon to Monster Prom was mentioned, and lots of other titles in between. Plus, some of us have a bone to pick with a particular BAFTA nominee short list.If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.

The shield is back in action! I just walked out of Captain America: Brave New World, and I'm bringing you my full reaction! From thrilling action to powerful performances, this movie delivers a bold new chapter for the MCU. Let's break down what makes this film a must-watch and why Sam Wilson is the perfect hero for this moment.

Emmanuel and Sofia talk about Sam Wilson in the latest Captain America sequel! Thadeus Ross is back and redder than ever!

Join Ron and Chris as they give their initial *spoiler filled* thoughts on Captain America: Brave New World, in addition to announcing some exciting news regarding the future of the show!Supes and Sabers announcement videohttps://youtu.be/cLeDsEHfvh8?si=AqI0-way_c5xWKw-Also We have a discord now! Join it here: https://discord.gg/QfDYKZSUKGEmail: Marvelplusrecaps@gmail.comTwitter: @toinfinitysagaFacebook: Facebook.com/infinitysagabeyondAnchor: https://anchor.fm/infinitysagabeyondBlog: https://infinitysagabeyond.wordpress.com/LinkTree: https://linktr.ee/toinfinitysagaandbeyond

Following the swift completion of the recent Futures Rewritten Ultimate Race to World First, we have assembled a crack team of panalists to discuss the raid and the drama that followed. Mr Happy is fresh off his completion of the Ultimate. Llamatodd joins the show for the first time after casting the first clear moments. Okaymage is still in the Echo studio! So add-us-on to your schedule, plugin your headphones and listen to these tools.