Podcasts about world first

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Best podcasts about world first

Latest podcast episodes about world first

The Dance Of Life Podcast with Tudor Alexander
F.E.N.N.E.C. — The Ultimate (World First) Christian Learning Companion

The Dance Of Life Podcast with Tudor Alexander

Play Episode Listen Later Mar 18, 2026 68:14


F.E.N.N.E.C. is a world first in the Christian education space. He is trained on over 1000 hours of content and hundreds of questions, and he can help you study in several ways. Ask him any question on the bible, theology, health or any topic in between. Have fun taking quizzes on a variety of topics, or sit in the hot seat and take questions that listeners have sent me over the years and try to answer them yourself. Whatever you choose, F.E.N.N.E.C. is the ultimate learning companion that can take your learning to the next level and make knowledge an adventure. * 00:00 - Introduction* 02:19 - FENNEC's 3 Modes* 12:21 - Accessing FENNEC* 19:36 - Librarian Mode* 27:43 - Quiz Mode* 38:25 - Discussion Mode* 46:22 - Power User Commands* 49:59 - No Match* 51:39 - Foreign Language Mode* 1:03:15 - Voice Mode This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.danceoflife.com/subscribe

Screw it, Just Do it
How Piemonte Drinks Founders Nearly Lost Everything

Screw it, Just Do it

Play Episode Listen Later Mar 17, 2026 64:05


They didn't grow up in the drinks industry. They didn't have investors lined up. They had £12,000, two corporate jobs, and a spicy margarita made on a balcony during lockdown.In this episode of Screw It Just DO It, I sit down with Alice Parmiter and Wynter Karo, co-founders of Pimentae, to unpack how they turned a tequila knowledge gap into one of the UK's fastest-growing tequila cocktail brands.From discovering real tequila culture in Mexico to spotting a gap in UK supermarkets, they bootstrapped their first 1,400 bottles, hand-delivered influencer hampers, and then put £20,000 down to run a festival bar with no safety net.That decision funded their business.Since then, they've raised £2 million, scaled into grocery, travel and festival spaces, navigated a product recall, and built a brand rooted in community and authenticity.This is not a “glam startup” story. It's about blind optimism, operational mistakes, difficult fundraising conversations, and staying aligned as co-founders.Key Takeaways• Why blind optimism is often required at the start• How bootstrapping builds stronger commercial discipline• The risks of taking the wrong investor too early• Why festivals became their most powerful customer acquisition tool• How authenticity protects your brand as you scale

Screw it, Just Do it
The Future Of Alcohol Might Be No Alcohol | Claire Warner

Screw it, Just Do it

Play Episode Listen Later Mar 12, 2026 13:56


Claire Warner helped build Belvedere Vodka for 15 years.She created 13 expressions. She climbed the ranks inside LVMH. She understood how premium alcohol brands scale.Then she made a call most people would avoid.She decided the world did not need another vodka.In this Bite-Sized episode of Screw It Just DO It, Claire explains why she left a secure leadership position to build Æcorn Drinks, how a forgotten 16th century acorn wine recipe became the foundation of a modern aperitif, and why launching three complex products at once was a risk worth taking.We also unpack what it means to build your own identity as the sister brand to Seedlip, how Covid disrupted their first real summer, and why innovation in this space has to be flavour-led, not alcohol-led.This is not about sobriety. It is about redefining the ritual.Key Takeaways• Why experience in a category can become a reason to leave it• The strategic risk of launching multiple SKUs at once• How to build brand distinction when linked to a market pioneer• Why aperitif culture matters more than alcohol percentage

Screw it, Just Do it
We Spent 2.5 Years Developing Fabric Before Selling One Item | Rory MacFadyen of Reflo

Screw it, Just Do it

Play Episode Listen Later Mar 10, 2026 41:57


Rory MacFadyen never planned to run an apparel brand.He was on a solid corporate trajectory in sport. Middle East sponsorship deals. Major events. A comfortable path.Then he saw the scale of waste in sportswear.At the same time, his best friend Pete discovered how to turn unlimited plastic waste into performance fabric.That was the spark.In this episode of Screw It Just DO It, Rory shares how Reflo was born, why they spent two and a half years developing sustainable performance fabrics before launching, and how they went from being doubted to landing partnerships with the Australian Open and the WM Phoenix Open.We talk about rejection, tall poppy syndrome in the UK, raising growth capital, bringing Harry Kane in as an investor, and why entrepreneurship is far harder than people think.This is not a fast-fashion story.It's about long-term thinking, graft, resilience, and trying to flip an industry on its head.Key Takeaways• Why there is never a perfect time to launch• How to build credibility before you look big• Why founders must sell, not just manage• The truth about hustle culture and burnout• How to build a brand rooted in mission, not marketing

Screw it, Just Do it
Winning The Apprentice Was Just the Start

Screw it, Just Do it

Play Episode Listen Later Mar 6, 2026 12:12


When Dr Leah Totton applied for The Apprentice, she was a full-time NHS doctor with no business experience and a clear career path ahead in Obstetrics and Gynaecology.She didn't expect to win.But winning meant walking away from certainty and stepping into the unknown with Lord Alan Sugar as her business partner.In this episode, I sit down with Leah to unpack what really happened after the cameras stopped rolling. The cash flow stress. The competitor who copied her business model before she even opened. The shock of realising that even after national TV exposure, nobody was queuing outside the clinic.This is the reality of building a service-based business.Leah shares the mindset shift from doctor to entrepreneur, the discipline of sector expertise, and why quality control matters more than rapid scale. We also dive into her seven-year journey to launch a skincare line that she refused to rush, despite pressure to “just put something out”.If you are thinking of starting a clinic, a product brand, or any service-led business, this conversation is a masterclass in resilience and execution.Key TakeawaysGetting customers is harder than launching: Opening the doors is easy. Building trust takes years. Especially in health and aesthetics.Sector expertise protects your business: If you cannot deliver the core service yourself, scaling becomes fragile.Thick skin is not optional: Business is not personal. The sooner you understand that, the faster you grow.Quality compounds: Short-term speed can damage long-term trust. Leah chose slower growth with stronger foundations.

Contrabass Conversations double bass life
1135: John Mietus and the World-First "Butterfly Lovers" on Double Bass

Contrabass Conversations double bass life

Play Episode Listen Later Mar 5, 2026 47:21


John Mietus is a composer, double bassist, and conductor, currently Associate Principal Bass with the Auckland Philharmonia. Born in Hong Kong and raised in Ohio, John started playing bass at age four and went on to study with some legendary teachers while building a career that spans orchestral playing, chamber music, teaching, and composition. In this episode, John and Jason dig into John's world-premiere performance of the "Butterfly Lovers Violin Concerto" (He Zhanhao and Chen Gang) on double bass with orchestra in Changsha, China, on January 1, 2026, and what it took to make a faithful transcription of such an iconic work. John shares how he approached the arranging process, why he ultimately chose fifths tuning, the practical realities of living in that tuning for months, and the string setup that helped him pull it off. They also discuss expanding the bass repertoire through transcription, the ways conducting and composing enhance a bassist's musicianship, and John's work as a teacher. Enjoy, and follow John on his website, Instagram, and YouTube!   Connect with DBHQ Join Our Newsletter Double Bass Resources Double Bass Sheet Music Double Bass Merch Gear used to record this podcast Zoom H6 studio 8-Track 32-Bit Float Handy Recorder Rode Podmic Sony Alpha 7 IV Full-frame Mirrorless Interchangeable Lens Camera Sony FE 16-35mm F2.8 GM Lens Sony FE 24-70mm F2.8 GM Lens   When you buy a product using a link on this page, we may receive a commission at no additional cost to you. Thank you for supporting DBHQ.   Theme music by Eric Hochberg

Screw it, Just Do it
Robert Hanna: I Didn't Want The Wage To Be The Cage

Screw it, Just Do it

Play Episode Listen Later Mar 3, 2026 65:22


When I sat down with Robert Hanna, I did not hear a story about failure. I heard a story about comfort.He was a director at a legal recruitment firm. Well paid. Progressing. Respected. By most standards, successful.But approaching his 30th birthday, he realised something uncomfortable. He was building someone else's legacy, not his own.That realisation led to a decision. Start his own legal recruitment agency. Then take a bigger risk. Launch The Legally Speaking Podcast, not as a hobby, but as a long-term personal branding strategy.Today, that podcast is a global legal careers platform. It attracts high-quality clients, builds community in the legal industry, and has secured sponsorship from a $5bn legal tech unicorn.In this episode, we break down how personal branding, niche community building, strategic partnerships and content repurposing can transform a professional services business.If you are a founder thinking about building authority, launching a podcast, or turning content into commercial leverage, this conversation is practical and direct.Key TakeawaysComfort can quietly limit ambition. Ownership changes everything.Personal branding is not vanity. It is commercial leverage.Niche communities outperform broad audiences in professional services.Evergreen content becomes an asset when treated strategically.Strategic partnerships accelerate growth faster than going alone.

Screw it, Just Do it
From SAS To Everest: The Decision That Shifted Everything

Screw it, Just Do it

Play Episode Listen Later Feb 26, 2026 11:48


Jay Morton spent 14 years in the British military, including 10 Jay Morton spent 14 years in the British military, including 10 years in the SAS Special Air Service.Then one quiet moment in the Alps changed everything.In this Thursday Bite-Sized episode of Screw It Just DO It, Jay shares the exact moment he realised there was more to life than chasing promotion inside the Special Forces.Standing on a mountain ridge, eating a sandwich, he made a decision that would take him from elite military operator to two-time Mount Everest summitier and high performance expedition leader.We talk about:Leaving a high-status career without a rigid planWhy Everest became the next proving groundThe difference between physical toughness and mental resilienceWhy growth only happens when you deliberately make life hardJay reflects on summiting Everest twice, guiding clients through extreme pressure, and why he refuses to reach the end of life with regret.

Catholic Preaching
Becoming People of Prayer Inspiring People All Across the World, First Thursday of Lent, February 26, 2026

Catholic Preaching

Play Episode Listen Later Feb 26, 2026 21:56


Msgr. Roger J. Landry St. Francis Xavier Parish, Owo, Nigeria Site of the Massacre of 41 Christians on June 5, 2022 Thursday of the First Week of Lent February 26, 2026 Esther 12.14-16, 23-25, Ps 138, Mt 7:7-12   To listen to an audio recording of today’s homily, please click below:  https://traffic.libsyn.com/secure/catholicpreaching/2.26.26_Homily_St._Francis_Xavier_Owo.mp3   The outline […] The post Becoming People of Prayer Inspiring People All Across the World, First Thursday of Lent, February 26, 2026 appeared first on Catholic Preaching.

Screw it, Just Do it
Do It Before Someone Else Does | From 500 to 16,000 with Dr. Raphael Sofoluke

Screw it, Just Do it

Play Episode Listen Later Feb 24, 2026 47:51


In this episode of Screw It Just DO It, I sit down with Dr. Raphael Sofoluke, founder and CEO of the UK Black Business Show.Raphael didn't start with funding.He didn't start with a team.He didn't even start full-time.He had an idea, six months, and a belief that representation mattered.From a 500-person event at the QE2 Centre to a week-long series attracting 16,000 attendees, Raphael shares the real story behind building one of the UK's most impactful business platforms.We talk about speed over perfection, juggling a full-time job while building something bigger, why being audacious matters, and how the new partnership with Stephen Bartlett and Flight Story aims to drive £100 billion in economic impact over the next decade.This conversation is about execution, ambition, and refusing to think small.Key TakeawaysSpeed beats perfection. First to market with strong execution wins.Learn and earn before you leap. Industry experience compounds.Longevity matters more than hype. Execute with excellence consistently.Impact is the real metric. Revenue follows vision and representation.

Screw it, Just Do it
The Day Redundancy Forced A Decision with Timo Mullen

Screw it, Just Do it

Play Episode Listen Later Feb 19, 2026 6:38


Timo Mullen is the co-founder of Foam Life, a sustainable flip flop brand built after he and his co-founder lost their six-figure jobs during the pandemic.In this Bite-Sized episode of Screw It Just DO It, Timo shares the moment they stopped waiting for certainty and chose action instead. From designing their first product in a week to securing pre-orders, raising investment, and expanding into international markets, this conversation breaks down what really happens when founders remove the safety net.Timo also explains why regret became a bigger risk than failure, how accountability drives momentum, and why word of mouth matters more than paid marketing when you are building something real.Key TakeawaysRegret is heavier than failure when you do not actRemoving the safety net forces clarityMomentum comes from action, not planningSustainability works when it is built in from day one

Screw it, Just Do it
She Walked Away From Law And Built Coffee Republic

Screw it, Just Do it

Play Episode Listen Later Feb 17, 2026 49:25


In this episode of Screw It Just DO It, I sit down with Sahar Hashemi OBE, co-founder of Coffee Republic and the force behind Buy Women Built.Sahar shares the moment that changed everything. Trapped in a legal career that did not fit, she was forced to confront how short life really is. Instead of waiting for clarity, confidence, or permission, she acted.We talk about why most founders overthink instead of starting, why customer experience always wins, and why small, doable steps matter more than perfect plans. Sahar also explains why female entrepreneurship in the UK still lags behind other developed countries and what Buy Women Built is doing to change that.This conversation is for anyone sitting on an idea, feeling restless, or waiting for the right moment.Key TakeawaysWhy waiting is often riskier than taking actionHow starting small creates momentum and clarityWhy customer obsession builds resilient businessesHow visibility and role models change belief and behaviour

Screw it, Just Do it
What Elite Sport Teaches You About Building a Business with Matt Richards MBE

Screw it, Just Do it

Play Episode Listen Later Feb 10, 2026 61:19


Matt Richards MBE is a two time Olympic champion who understands pressure at the highest level. In this episode of Screw It Just DO It, Matt shares how self belief was built early, tested at the 2024 Olympics, and later applied to building a business while still competing at an elite level.We talk about dealing with doubt, staying consistent when outcomes are uncertain, and why feedback and focus matter when you are building something new.Key TakeawaysHow Matt rebuilt belief under Olympic pressureWhy consistency beats confidence during uncertain momentsWhat elite sport teaches you about execution and focusHow feedback shaped Matt's move into business

Addicted to the Mouse: Planning Disney World, Disneyland, and All Things Disney
Answering the 50 Most Asked Questions From Disney World First Time Visitors

Addicted to the Mouse: Planning Disney World, Disneyland, and All Things Disney

Play Episode Listen Later Feb 2, 2026 59:49


On today's Disney Podcast, we are answering the 50 most asked questions online from guests who are planning a Disney World vacation and have never been before. From what is Lightning Lane to whether you should stay on property or not, we’re getting into all of them. Enjoy! This episode is sponsored by Fantastical Vacations. For free concierge vacation planning, specializing in Disney and Universal Vacations, visit https://www.fantasticalvacations.com We would love you to join us on Patreon! Thanks so much for supporting the show. We also have Addicted to the Mouse Merchandise! You can check it out at https://addictedtothemerch.com Thanks so much for listening! If you like what you hear, please subscribe and catch us every Sunday for the podcast. Join us every Sunday and Wednesday evening as we take you to Walt Disney World, Disneyland, on Disney Cruise Line, Universal Studios and everywhere in between! We can be found at www.addictedtothemouse.com and be reached at danandleslie@addictedtothemouse.com Please also connect with us here: Patreon – https://www.patreon.com/addictedtothemouse Youtube – https://www.youtube.com/@AddictedtotheMouse Facebook – https://www.facebook.com/AddictedtotheMouse/ Instagram – https://instagram.com/addictedtothemouse/ The post Answering the 50 Most Asked Questions From Disney World First Time Visitors appeared first on Addicted to the Mouse.

The Daily Aus
The world-first social media court case

The Daily Aus

Play Episode Listen Later Feb 2, 2026 14:33 Transcription Available


This week, some of the world's biggest tech companies are facing a landmark trial in the U.S. Meta, which owns Instagram and Facebook, along with YouTube, are being sued over claims that their platforms are designed to be addictive to children and harm their mental health. The first in a series of trials will take place in LA, but could reshape how social media works worldwide. Today, we’ll explain what's happening, how we got here, and what it could mean for young people everywhere, including here in Australia. Hosts: Emma Gillespie and Billi FitzSimonsProducer: Orla Maher Want to support The Daily Aus? That's so kind! The best way to do that is to click ‘follow’ on Spotify or Apple and to leave us a five-star review. We would be so grateful. The Daily Aus is a media company focused on delivering accessible and digestible news to young people. We are completely independent. Want more from TDA?Subscribe to The Daily Aus newsletterSubscribe to The Daily Aus’ YouTube Channel Have feedback for us?We’re always looking for new ways to improve what we do. If you’ve got feedback, we’re all ears. Tell us here.See omnystudio.com/listener for privacy information.

Highlights from The Pat Kenny Show
We hear about the world first AI i tool kit!

Highlights from The Pat Kenny Show

Play Episode Listen Later Jan 16, 2026 11:18


World's first research-backed intervention reduces harmful engagement with AI-generated explicit imagery. As the Grok AI-undressing controversy grows, researchers say user education must complement regulation and legislation. All to discuss with Dr Gillian Murphy, UCC School of Applied Psychology and research project Principal Investigator.

Gamereactor TV - English
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - English

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Italiano
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Italiano

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Norge
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Norge

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Español
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Español

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Inglês
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Inglês

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Suomi
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Suomi

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Sverige
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Sverige

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - France
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - France

Play Episode Listen Later Jan 15, 2026 33:49


Gamereactor TV - Germany
Wario World - First 30 minutes on Nintendo Switch 2 (NSO Gamecube)

Gamereactor TV - Germany

Play Episode Listen Later Jan 15, 2026 33:49


Netiv.net - Weekly Torah Class
When_the_World_First_Tilted__The_Mystical_Roots_of_Idolatry

Netiv.net - Weekly Torah Class

Play Episode Listen Later Dec 13, 2025 60:29


When_the_World_First_Tilted__The_Mystical_Roots_of_Idolatry

Amanda Joy's Podcast
HypnoGeeks Podcast Episode 24 with Cormac Colleran & Dr. Jodie Solberg SFTI Hypnosis Academy

Amanda Joy's Podcast

Play Episode Listen Later Dec 12, 2025 90:23


Addiction isn't the problem; it's a solution the subconscious found to deal with something deeper. But what if there was a way to address that deep-seated need, creating permanent freedom instead of temporary fixes?Welcome back to HypnoGeeks! We're diving into the cutting-edge of healing, where solution-focused techniques meet trauma-informed care to redefine transformation.In this truly inspiring episode, we sit down with Cormac Colleran (Creator of the powerful ICAAN Method from Ireland) and Dr. Jodie Solberg (International best-selling author and founder of the RESTORE Process for Trauma from the US). Together, they are the co-founders of the SFTI Hypnosis Academy and share over 40 years of combined experience helping thousands heal from trauma, anxiety, addiction, and unwanted patterns.This conversation is close to the host's heart, and you'll discover the World-First protocol they've created that is empowering practitioners to create lasting change at the subconscious level.In this transformative episode, you will learn: The Core Driver: Why Dr. Jodie says, "Trauma is often the hidden driver behind addictive patterns," and how their approach helps clients finally release what's been holding them back. The Solution, Not the Problem: How Cormac's perspective "Addiction isn't the problem, it's the solution," opens the door to authentic, sustainable freedom. The SFTI Difference: A breakdown of how the blend of Solution-Focused and Trauma-Informed care makes change not just possible, but inevitable. Identity Over Habit: Why helping a client shift their core identity is infinitely more powerful than simply addressing a behaviour or habit. Language of Healing: The critical distinction between "temptation" and "craving," and the protocol they use for "washing away temptation."This is essential listening for hypnotherapists, coaches, or anyone looking to understand the deepest roots of addiction and anxiety. Get ready for a conversation that's not only informative but truly transformational.Join the movement to empower practitioners with confidence.Let's welcome Cormac and Jodie to the show!Support the showThis podcast is sponsored by The Northern College of Clinical Hypnotherapywww.thenortherncollegeofclinicalhypnotherapy.com

WSJ What’s News
Australia Bans Under-16s From Social Media in World First

WSJ What’s News

Play Episode Listen Later Dec 10, 2025 13:55


A.M. Edition for Dec. 10. In a move being watched by governments around the world, Australia implements a landmark law banning children under 16 years old from popular social-media platforms. Listen to our Sunday episode on the growing push to ban social media for kids. Plus, with the Federal Reserve expected to cut interest rates today, WSJ deputy finance editor Quentin Webb breaks down the growing divide among policymakers about the road ahead. And Miami swings Democratic for the first time in decades, the latest in a recent string of party victories. Luke Vargas hosts. Sign up for the WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today in Focus
The social media ban for kids: Australia's world-first experiment – podcast

Today in Focus

Play Episode Listen Later Dec 10, 2025 28:31


Today in Focus talks to three teenagers, and technology reporter Josh Taylor, about Australia's world-first legislation: a social media ban for under-16s. Help support our independent journalism at theguardian.com/infocus

Capital FM
China Launches World-First Technical Validation System for New Energy Vehicle Safety and Standards

Capital FM

Play Episode Listen Later Dec 9, 2025 7:23


China Launches World-First Technical Validation System for New Energy Vehicle Safety and Standards by Capital FM

Full Story
'No playbook for this': the eSafety commissioner on her world-first social media ban

Full Story

Play Episode Listen Later Dec 9, 2025 18:01


Today more than a million teenagers will wake up to find they have been locked out of social media sites such as Instagram and TikTok as Australia's world-first social media ban for under-16s comes into force. Guardian Australia technology reporter Josh Taylor speaks to Julie Inman Grant about how she plans to enforce the move, why it could fail and how taking on the tech giants has come at a personal cost

Insiders
Australian kids brace for a world-first experiment as they're booted off social media

Insiders

Play Episode Listen Later Dec 6, 2025 50:36


Australian kids are bracing for a world-first experiment as they're booted off social media, while the parliament winds up after a huge year. 

Basically Minimal - Minimalist
23: Solo Travel | Nintendo World | First Solo Trip

Basically Minimal - Minimalist

Play Episode Listen Later Nov 26, 2025 33:25


On today's episode we are going to talk about my solo girl traveling. First stop: Nintendo World!  Follow on Instagram: @thebeachclassroomWelcome to basically minimal where we'll talk about all things cleaning, being lucky, and living an intentional life. 

AM full episode
World-first deal for delivery drivers

AM full episode

Play Episode Listen Later Nov 24, 2025 20:10


Better pay and protections for delivery drivers in a world-first deal.

AM
World-first deal for delivery drivers

AM

Play Episode Listen Later Nov 24, 2025 20:10


Better pay and protections for delivery drivers in a world-first deal.

The Agenda
"Another Pointless World First"

The Agenda

Play Episode Listen Later Nov 24, 2025 30:28


On today's episode of The Agenda, it's another pointless world first for the ACC as Finn Caddie joins ACC Head G Lane on the road to Whangarei (00:00)! While the fellas head up to join Lou Vincent, Joey Yovich and Davey as they attempt a new Guinness World Record for farthest catch of a hit golf ball, they recap a massive weekend of sport, including the All Blacks beating Wales to end the 2025 season on a win (06:10).Then, they cross to the Cricket Desk to recap the 1st Ashes Test (10:00), and the Black Caps sweeping the Windies (13:30)...Finally, they chat about the drama in the Vegas Grand Prix (17:55) and brainstorm what Dan Hooker's next 1 Minute Scrap should be (22:10)... Did you know that we've launched a new Facebook Group called 'The Caravan' JOIN HERE! Brought to you by Export Ultra! Follow The ACC on Instagram or Facebook or TikTok Subscribe to The Agenda Podcast now on iHeartRadio, YouTube, or wherever you get your podcasts! iHeartRadio Apple Spotify YouTube THANKS MATE! See omnystudio.com/listener for privacy information.

Tasmanian Country Hour
World first at Tasmanian shearing shed

Tasmanian Country Hour

Play Episode Listen Later Nov 14, 2025 8:56


Tasmania's newest shearing shed with a world first inclusion has passed its first ever test by shearers with a big tick of approval.

Tasmanian Country Hour
World first at new Tasmanian shearing shed

Tasmanian Country Hour

Play Episode Listen Later Nov 14, 2025 52:08


Rural news and events from Tasmania and the nation.

Irish Tech News Audio Articles
Research shows world-first breakthrough for bowel cancer immunotherapy

Irish Tech News Audio Articles

Play Episode Listen Later Oct 29, 2025 6:45


Professor Aideen Ryan, Professor in Tumour Immunology at University of Galway's College of Medicine, Nursing and Health Sciences. Photo: Andrew Downes Researchers at the University of Galway have revealed the results of a world-first study into how bowel cancer shuts down the immune system, and how this can be reversed to improve treatment. The findings have been published in the Journal for ImmunoTherapy of Cancer (JITC). Breakthrough for bowel cancer immunotherapy The research team showed how structural stromal cells switch off the immune system and how the body's own killer cells can be switched back on, opening up the opportunity for a completely new approach to optimising immunotherapy for patients. Colorectal cancer - commonly referred to as bowel cancer - is one of the world's most common cancers and the second leading cause of cancer death worldwide. Diagnoses in people under 50 have been climbing in recent decades, with recent global analysis showing these early-onset cases have almost doubled since 1990. In Ireland, the disease affects more than 2,500 people a year. Professor Aideen Ryan, Professor in Tumour Immunology at University of Galway's College of Medicine, Nursing and Health Sciences, said: "While immunotherapy has revolutionised care in cancers such as melanoma and lung cancer, it has shown very limited benefit in bowel cancer, leaving patients with advanced disease with few treatment options and poor survival outcomes." The breakthrough research discovery is the first to demonstrate that tumour stromal cells - the structural cells that support cancer growth - are directly reprogramming the immune system. They do this by switching off, or hijacking, two of our body's most important tumour-fighting cells - the natural killers (NK) and macrophages - rendering them unable to attack the cancer. Professor Ryan said: "The interaction between the cancer, our body's healthy cells and our defence mechanism is a complex one, but our research shows that the cancer is essentially creating an immune brake - it is blocking the body's natural response and fight mechanism." What has been discovered in relation to how the cancer interacts with the human body? Tumour stromal cells are the structural cells which allow the cancer to grow. They are coated in sugars called sialoglycans. These interact with receptors on the body's immune cells called Siglecs. This interaction causes the body's natural defence response to be switched off and unresponsive when immunotherapy is used, and therefore unable to attack the cancer. The research identified a specific enzyme that drives this process of 'switching off', as it produces the Siglec-binding sugars on stromal cells. When the researchers blocked this pathway using drugs called sialidases, they could show that the body's most important tumour-fighting cells - the natural killers (NK) and macrophages - reactivated. It showed that the tumours shrank and the spread of cancer, known as metastasis, was prevented. The multidisciplinary research was conducted in collaboration with colorectal surgeons and pathologists at Galway University Hospital, led by Professor Aisling Hogan and Professor Sean Hynes; as well as experts in colorectal cancer - Dr Philip Dunne, Queen's University Belfast and experts in targeting sialoglycans at Palleon Pharmaceuticals, MA, USA, who have developed sialidase drugs that disrupt the sialoglycan-Siglec interaction. Professor Ryan added: "Our research is a clear breakthrough in our understanding of bowel cancer and how immunotherapy could be more successful. This world-first finding shows that some of the bowel cancer cells are not just passive bystanders, they are actively reprogramming the body's immune cells, preventing them from doing their job. We have uncovered an entirely new checkpoint and by focusing on it we can reactivate the immune system and improve our body's innate ability to fight the disease, and even target metastasis." Michael O'Dwyer, Pro...

The PoddyC
Ep. 85 - The Future of The Race to World First w/ Meeres

The PoddyC

Play Episode Listen Later Oct 21, 2025 113:22


Hello folks, we're back once again. This time Maximum & Dorki are joined by the legendary Meeres while Dratnos is locked away in a cellar somewhere. Meeres is here to give us some great insight on the future of WoW and his opinions on the upcoming changes to midnight. Hope you enjoy!For Business Inquiries:Poddymanagement@gmail.com

The Briefing
Australia's world-first climate shift + Our phone-fueled sex criminals

The Briefing

Play Episode Listen Later Oct 15, 2025 19:55


Thursday Headlines: Israel says one of four bodies handed over by Hamas is not a hostage, three Australian men accused of Bali villa shooting could face the death penalty, the world’s carbon dioxide levels have reached record highs, NRL players now face 10-year ban for joining rival competition, and Virgin Australia’s pets on flights trial is underway! Deep Dive: New research has revealed the worst offenders for image-based sexual abuse in Australia, including those who create deepfakes and revenge porn, or take photos and videos without consent. The Australian Institute of Criminology says such crimes are disproportionately carried out by young men, while the type of offending differs across age groups and genders. In this episode of The Briefing, Tara Cassidy speaks with AIC research manager Tom Sullivan about what's needed to address the growing problem, and how tech advancements are making it harder to stop. Follow The Briefing: TikTok: @thebriefingpodInstagram: @thebriefingpodcast YouTube: @TheBriefingPodcastFacebook: @LiSTNR Newsroom See omnystudio.com/listener for privacy information.

RNZ: Morning Report
Hospice New Zealand launches world-first review

RNZ: Morning Report

Play Episode Listen Later Oct 13, 2025 3:55


Hospice New Zealand have launched a world-first project inviting people who are dying and their caregivers to review the everyday services around them. Hospice NZ Chief Executive Wayne Naylor spoke to Ingrid Hipkiss.

She's On The Money
Money Confessions: What It Actually Costs to Launch a World-First Product (While Juggling 2 Kids and a Mortgage)

She's On The Money

Play Episode Listen Later Oct 5, 2025 32:24 Transcription Available


Ever wondered what it really costs to turn a light-bulb moment into something real? This week’s Money Diarist is a mum of two who did exactly that. She created a world-first product that launched just two weeks ago, and now she’s here to do what most founders wouldn’t: spill on every dollar it took to make it happen. From losing out to a dodgy sourcing agency to somehow pulling together $200K through pure determination, she’s laying it all out... the risks and the real-world chaos of betting on yourself. Inside the ep, we what it actual costs to get a product made, and how she’s juggling start-up life, toddler meltdowns, and a mortgage. It’s messy, bold, and so unbelievably relatable. GET VICTORIA'S BUDGETING SYSTEM: Master your cashflow here.Ready to binge more relatable, inspiring, and downright juicy money stories? Check out our ultimate Money Diaries playlist. Listen now Join our Facebook Group AKA the ultimate support network for money advice and inspiration. Ask questions, share tips, and celebrate your wins with a like-minded crew of 300,000+. And follow us on Instagram for Q&As, bite-sized tips, daily money inspo... and relatable money memes that just get you. Acknowledgement of Country By Nartarsha Bamblett aka Queen Acknowledgements. The advice shared on She's On The Money is general in nature and does not consider your individual circumstances. She's On The Money exists purely for educational purposes and should not be relied upon to make an investment or financial decision. If you do choose to buy a financial product, read the PDS, TMD and obtain appropriate financial advice tailored towards your needs. Victoria Devine and She's On The Money are authorised representatives of Money Sherpa PTY LTD ABN - 321649 27708, AFSL - 4See omnystudio.com/listener for privacy information.

Mountains of Magic
Ep 318 - 10 Mistakes Walt Disney World first timers make

Mountains of Magic

Play Episode Listen Later Oct 3, 2025 21:41


If you are a Disney World newbie, don't make these mistakes! Today I'll share 10 problems new Walt Disney World guests tend to have, and how you can avoid them. Follow along for my favorite Walt Disney World tips, and don't miss future episodes for those new to Walt Disney World. I hope you enjoyed today's show. I'd love to connect with you over on Instagram @mountains_of_magic or Facebook at Fantastical Vacations by Daniele. If you would like help in planning an upcoming Disney or Universal vacation, email me at danielerobbins@fantasticalvacations.com or fill out a quote form to get started planning the magic Get A Quote Want the latest travel deals and all my tips for Disney, Universal and Cruising?Join my email newsletter  Want to try fetch rewards and get free gift cards by scanning receipts? Use my code 8G48W to get 2000 points at sign up. FETCH REWARDSMy Website mountainsofmagic.square.siteMusic from Uppbeat (free for Creators!):https://uppbeat.io/t/andrey-rossi/bring-the-funLicense code: E9BZCTS1O3JRPERX This podcast is not sponsored or supported by Fetch Rewards. Views of the host are her own. 

RNZ: Morning Report
Kiwi women join world-first heart attack trial

RNZ: Morning Report

Play Episode Listen Later Sep 28, 2025 4:50


New Zealanders will be part of a world-first clinical trial into how to treat a dangerous condition that causes heart attacks in young women - including new mothers. Grant recipient and senior researcher, Caroline Alsweiler spoke to Corin Dann.

The PoddyC
Ep. 80 - WINNING THE RACE TO WORLD FIRST (AGAIN, AGAIN)

The PoddyC

Play Episode Listen Later Sep 1, 2025 111:58 Transcription Available


Hello friends and enemies of the PoddyC Podcast. In this weeks episode we are talking about Liquid Sweeping the war within, boss tuning, everything that's happened since 11.2 came out, and so many more things it's kinda crazy. This episode is stacked and you better enjoy it.For Business Inquiries: Poddymanagement@gmail.com

Blizzard Watch
Tazavesh is the best city ever, and more WoW patch 11.2 observations

Blizzard Watch

Play Episode Listen Later Aug 15, 2025 66:57


This week our host is our special guest, Liz Patt, who has a lot of opinions on Diablo, but she's also here for a discussion of patch 11.2. The team love Tazavesh, 10/10 city, no notes, though they remain a little skeptical of Broker culinary pursuits. We also looked at the Race to World First, which is underway as raid guilds contend to see who can get the first Mythic kill of Dimensius. Plus, General Manager Rod Fergusson has left Diablo, and we aren't quite sure what that means for the series. And in a segue which is no way jarring, we turn from Diablo to the Wholesome Games Festival on Steam, and some of the cute and cozy titles we enjoyed from that showcase.If you have a few minutes, please fill out our survey to tell us what you think about the podcast. This data is collected by our podcast host, Acast, and will be used to help us improve the show as well as attract potential sponsors. Your answers are completely anonymous. We appreciate your help!If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.

For Azeroth!
#341 - For Azeroth!: "You Can't Have It All"

For Azeroth!

Play Episode Listen Later Aug 14, 2025 67:53


Sean, Lex, and Manny discuss the official reveal of Legion Remix, the slow start to Manaforge: Omega's Race to World First, and the wealth of content coming in the World of Warcraft.

The PoddyC
Ep. 79 - Drama, The Race to World First & 11.2

The PoddyC

Play Episode Listen Later Aug 9, 2025 82:40 Transcription Available


Hello friends and enemies of the PoddyC Podcast. In this weeks episode we are discussing all things Race to World First, 11.2 being launched and a bunch of Drama - because that's important! hope you enjoy!For Business Inquiries:Poddymanagement@gmail.com

Blizzard Watch
The waiting room for patch 11.2

Blizzard Watch

Play Episode Listen Later Aug 1, 2025 62:12


Cory joined us for this week's show, and by coincidence there was also a Heroes of the Storm patch the day they recorded. What are the odds? Not very good, if you ask Cory. There was also a new Hearthstone Battlegrounds season to discuss. We're all very much looking forward to next week, when patch 11.2 finally releases, and we learn more about what Xal'atath has cooking. The Race for World First also already has our attention. We'll miss Void Storage, though.Plus, this week we had a lot of time for listener questions, so don't forget to send those in. Sometimes we have a ton going on so we don't get to them, but they're always fun to answer. You can address them to podcast@blizzardwatch.com or ask them in the #queue-and-podcast-questions channel on our Discord server.If you have a few minutes, please fill out our survey to tell us what you think about the podcast. This data is collected by our podcast host, Acast, and will be used to help us improve the show as well as attract potential sponsors. Your answers are completely anonymous. We appreciate your help!If you enjoy the show, please support us on Patreon, where you can get these episodes early and ad-free! Hosted on Acast. See acast.com/privacy for more information.