Podcasts about nck

Rob Armstrong, CEO of Artax Biopharma, highlights the basic mechanism of action of Nck modulators and how they differ from traditional immunosuppressant drugs to treat autoimmune diseases. Taking this adjustable thermostat approach aims to modulate the immune response rather than completely suppressing the response, potentially reducing side effects. The oral, small molecule drug is an advantage over injectable biologics currently dominating the automimmune disease treatment landscape. Rob explains, "Nck stands for non-catalytic kinase, and what Nck is is an adapter protein that interacts with the T cell receptor. Its role is basically to amplify any signals when an antigen is presented to the T cell receptor. It's really interesting because it's called signal one. In other words, it's the beginning of the immune cascade when an antigen is presented. And what's interesting is that it's upstream of what the target of most other drugs are, which are the cytokines that are the offending entities for many of the autoimmune diseases. So what Nck does basically is it amplifies different types of antigens that are bound to the T cell receptor." "So, T cell receptors are a fascinating construct of proteins because they need to address the binding of antigens that are across an incredibly different range of avidity. In other words, it has to be able to be activated by both very strong avidity antigens and weak antigens. So what Nck does is it amplifies the signal when the antigen is a weak antigen, but when it's a strong antigen, Nck is really not necessary at all. And that particular distinction is why we modulate the immune system instead of suppressing it."  #ArtaxPharma #AutoimmuneDiseases #AtopicDermatitis #immunomodulation #NckModulators #TCellActivation #psoriasis #Dermotology artaxbiopharma.com Download the transcript here

Rob Armstrong, CEO of Artax Biopharma, highlights the basic mechanism of action of Nck modulators and how they differ from traditional immunosuppressant drugs to treat autoimmune diseases. Taking this adjustable thermostat approach aims to modulate the immune response rather than completely suppressing the response, potentially reducing side effects. The oral, small molecule drug is an advantage over injectable biologics currently dominating the automimmune disease treatment landscape. Rob explains, "Nck stands for non-catalytic kinase, and what Nck is is an adapter protein that interacts with the T cell receptor. Its role is basically to amplify any signals when an antigen is presented to the T cell receptor. It's really interesting because it's called signal one. In other words, it's the beginning of the immune cascade when an antigen is presented. And what's interesting is that it's upstream of what the target of most other drugs are, which are the cytokines that are the offending entities for many of the autoimmune diseases. So what Nck does basically is it amplifies different types of antigens that are bound to the T cell receptor." "So, T cell receptors are a fascinating construct of proteins because they need to address the binding of antigens that are across an incredibly different range of avidity. In other words, it has to be able to be activated by both very strong avidity antigens and weak antigens. So what Nck does is it amplifies the signal when the antigen is a weak antigen, but when it's a strong antigen, Nck is really not necessary at all. And that particular distinction is why we modulate the immune system instead of suppressing it."  #ArtaxPharma #AutoimmuneDiseases #AtopicDermatitis #immunomodulation #NckModulators #TCellActivation #psoriasis #Dermotology artaxbiopharma.com Listen to the podcast here

The ASX 200 rose 6 points to 7937 (0.1%) in quiet trade ahead of the Budget. Banks were firm with the Big Bank Basket at $242.34 (+1.5%). Tariff proof fenced perhaps. CBA up 1.4% and insurers better too, QBE up 0.3%. REITs were a little mixed, GMG down 0.6% and SCG rising 0.6%. RPL was smashed 14.8% on news from OPT that it had missed Phase III end point. RPL owns 32% of the biotech. In the industrials, WOW and COL both giving back some of the optimism from Friday's ACCC report. Tech stocks also under pressure, WTC down 2.9% and 360 falling 4.4%. The All-Tech Index down 0.5%. Retail weaker, PMV down 2.9% with NCK off 2.0% and MYR down 2.1%. WES rose as did JBH.Resources were a mixed bag of lollies. BHP fell 0.6% with FMG up 3.2% on some broker upgrades. Gold miners were mixed, VAU down 3.2% with NST off 1.3% and BGL dropping 12.8% on change in substantial holding. MIN bounced 6.9% as the haul road reopened. Oil and gas flat, coal eased, NHC down 4.4% and WHC off with uranium sellers back. BOE down 3.5% and DYL falling 1.8%. In corporate news, JHX announced a huge US merger and dropped 14.5% on the news. HLI fell 25.6% as CBA said it may not renew its contract. SM1 curdled 12.0% on unimpressive results.Nothing on the economic front. Asian markets flat. 10-year yields back up to 4.42%.Want to invest with Marcus Today? The Managed Strategy Portfolio is designed for investors seeking exposure to our strategy while we do the hard work for you. If you're looking for personal financial advice, our friends at Clime Investment Management can help. Their team of licensed advisers operates across most states, offering tailored financial planning services.  Why not sign up for a free trial? Gain access to expert insights, research, and analysis to become a better investor.

Another day, another drubbing as the ASX falls 104 points to 7786 (1.3%) with banks soggy again. The Big Bank Basket down to $236.66 (-1.7%) with NAB and WBC the worst affected. MQG dropped another 1.4% with ASX off 3.8% despite good volumes recently. GQG fell 2.4% and CGF off 1.5%. REITs also in the seller's sights, GMG bucked the trend, up 0.5% and SGP off 1.0% with healthcare under pressure as the holy trinity of CSL, RMD and COH all lost ground. Industrials found it tough going today, TCL fell 1.9% with WES off 2.6% and BXB down 2.6% with ALL slipping 1.6%. Retail once again saw selling, JBH off 1.0% and NCK down 3.5%. Travel stocks all fell, significantly as did gaming stocks, tech slipped with WTC down 1.7% and XRO off 1.1% as the All-Tech Index dropped 1.1%. Resources were again a mixed bag; gold miners rallied but somewhat muted, RMS fell 8.7% on a disappointing mine plan, EVN rose 0.8% and NEM was up 1.5%. BHP and RIO all fell 1.8% with FMG finding some friends up 1.5%. Lithium remains depressed and uranium stocks mixed. PDN up 2.7% and DYL up 3.2%. Oil and gas stocks eased back. In corporate news, IPH fell 10.0% as the CFO quit. Nothing on the economic front with US CPI due tonight. Asian markets eased slightly and 10-year yields rose to 4.43%. US Futures slightly positive.Want to invest with Marcus Today? The Managed Strategy Portfolio is designed for investors seeking exposure to our strategy while we do the hard work for you. If you're looking for personal financial advice, our friends at Clime Investment Management can help. Their team of licensed advisers operates across most states, offering tailored financial planning services.  Why not sign up for a free trial? Gain access to expert insights, research, and analysis to become a better investor.

ASX 200 falls 29 points to 8483(0.3%). Banks steady as she goes ahead of CBA results later this week. MQG fell 0.9% and PNI sliding 4.2% with GQG up 3.1% on FUM numbers. REITs mixed as GMG fell 0.9% and SCG rose 1.1%. Healthcare better, RMD up 0.6% and PME up 0.5% with CSL bucking the trend down %. Industrials flat as retail came under some pressure on JBH results, reversing early gains after conference call. LOV down 2.2% and NCK falling 3.7% despite brokers positive. Travel stocks better, WEB up 0.8% and LNW doing well up 7.9%. DMP steady after the big run Friday. Tech stocks dominated by front page headlines for WTC again, the All-Tech Index down 1.0% with WTC off 4.4%.  In resources, iron ore stocks fell, FMG off 1.5% and RIO fell 1.2% on proposed tariffs in the US on aluminum. Gold miners held up, NEM up 0.7% and EVN up 0.3%. LYC continued higher up 1.9% with PLS down slightly on an earnings update. BSL rose 1.8% on Trump steel tariffs. Energy stocks mixed, STO up 0.4% with BPT firming 4.0%. In corporate news, ANN rose 8.1% on better-than-expected numbers, CAR crashed 6.5% on some disappointment on growth and US price rises and JBH down on rethink. SGR rallied 13.6% on news of proposals for its Queen Street Wharf complex in Brisbane. Citi upgraded its gold price forecast to US$2900 this year. In Asian markets, Japan unchanged, HK up 1.4% and China unchanged. 10-year yields at 4.39%.Why not sign up for a free trial? Get access to expert market insights and manage your investments with confidence. Ready to invest in yourself? Join the Marcus Today community.

 A quiet cautious session as the ASX 200 gave back 9 points to 8411. Down 21 points for the week after a torrid start. Banks were solid ahead of CBA results next week. The Big Bank Basket rose to $268.42 +0.2%) MQG slipped slightly with GQG down 1.3% with insurers steady. REITs better on lower 10-year yields, GMG up 0.6% and CHC up 0.5%. Industrials were mixed, and REA kicked 2.8% on broker upgrades. WES slid 1.1% with retail firm, PMV up 1.2% and SUL up 2.6%. Travel stocks also in demand, WEB up 2.6% and CTD rising 3.3%. DMP rose 21.3% like a cheesy crust as store closures were announced in Japan. Finally. Healthcare on the nose as RMD continues to stagger around after quarterly, down another 2.6%. CSL off 1.1% and PME falling 1.5%. Resources were generally weaker, though iron ore miners rose, BHP up 0.6% and FMG up 1.9%. Gold miners saw some profit taking, NST down 2.4% and WGX off 2.0%. Rare earths LYC up 6.1% on Chinese fears, and lithium stocks walloped as CATL rumoured to be reopening a lepidolite mine. PLS down 4.3% and LTR off 4.4%. Energy stocks fell, STO down 0.9% and WHC down 3.9% with uranium under pressure. In corporate news, MMS fell 10.4% on a broker downgrade, and NCK rose 10.5% on better-than-expected results. SIG guided up and rose 3.2%. Nothing locally on the economic front. Asian markets mixed, Japan down 0.6% and HK up 1.5% and China up 1.7%. 10-year yields slightly higher at 4.36%.Why not sign up for a free trial? Get access to expert market insights and manage your investments with confidence. Ready to invest in yourself? Join the Marcus Today community.

 The Nasdaq popped 1.04% to finish at 18,987.47, while the S&P 500 gained 0.4% to end at 5,916.98. The Dow Jones Industrial Average dipped 120.66 points, or 0.28%, to settle at 43,268.94. ASX SPI down 6. AMC in focus on huge merger deal. NCK warns on delays - Boss Energy, Charter Hall, Downer EDI, Mount Gibson Iron and Pacific Smiles all host AGMs. COMMODITIESGold hits 1-week high as Russia-Ukraine tensions boost rush to safety.Oil steadies as Sverdrup field restart counters geopolitical concerns.Iron ore at one-week high on softer dollar, pre-holiday stocking.Peru copper output edges down 1% in September.Norway's Sverdrup oil output rises to two-thirds of capacity.LME aluminium up as market adjusts to China's plan to end tax rebate.LME lead stocks jump to highest level in 11-1/2 years after inflows.Why not sign up for a free trial? Get access to expert market insights and manage your investments with confidence. Ready to invest in yourself? Join the Marcus Today community. 

Wykład Piotra Kubkowskiego w ramach projektu "Bioróżnorodność i woda w wiejskim dziedzictwie" realizowanego w ramach grantu „KPO dla Kultury”, sfinansowanego przez Unię Europejską NextGenerationEU [17 października 2024 r.] https://wszechnica.org.pl/wyklad/ochroniarze-wies-przyroda-w-oczach-krajoznawcow/ Co o wrażliwości ekologicznej początku XX wieku wyczytać można z tekstów krajoznawczych? Kiedy na przełomie XIX i XX wieku powstawał, a w dwudziestoleciu międzywojennym umacniał się ruch krajoznawczy, jednym z jego głównych zadań stało się „ochroniarstwo", które dziś nazwalibyśmy aktywizmem ekologicznym. Działalność w zakresie ochrony przyrody była solidnie zakorzeniona w ideologii krajoznawstwa - tę panoramę przekonań postaram się w wykładzie pokrótce przedstawić. W swoich wyprawach krajoznawcy kierowali kroki nie tylko ku „starożytnym" polskim miastom i niezamieszkałym leśnym głuszom, lecz także ku wiejskiej prowincji – stąd i stosunek chłopów wobec przyrody stawał się niejednokrotnie tematem artykułów i publikacji. Są to co prawda (najczęściej) relacje sporządzane „z zewnątrz", bywają więc protekcjonalne, a czasami wręcz pogardliwe, kiedy indziej zaś sentymentalne i romantyzowane. Wspólnie przyjrzymy się wybranym opowieściom o relacjach mieszkańców wsi i wiejskiej przyrody, co pozwoli nam lepiej zrozumieć fundamenty polskiej refleksji ekologicznej. Piotr Kubkowski jest adiunktem w Instytucie Kultury Polskiej UW. Zajmuje się kulturową historią turystyki, sportu i ciała, kulturą miejską (głównie w ujęciach historycznych), nowoczesną architekturą osiedlową. Autor książki "Sprężyści. Kulturowa historia warszawskich cyklistów". Współredaktor i współautor czterech książek o relacjach literatury z przestrzenią Warszawy (seria "Topo-Grafie") oraz wydawca wspomnień Marii Jadwigi Strumff, jednego z pierwszych queerowych tekstów polskich. Kurator i organizator wystaw w stołecznych muzeach. Wyróżniony stypendium MNiSW, Nagrodą Rektora UW i nagrodą NCK za najlepszy doktorat z zakresu nauk o kulturze, finalista Nagrody Literackiej Warszawy, laureat nagrody im. H. Szwankowskiej. Członek Stowarzyszenia Katedra Kultury, Pracowni Studiów Miejskich UW i Towarzystwa Krajoznawczego Krajobraz. Nagranie w ramach projektu "Bioróżnorodność i woda w wiejskim dziedzictwie" realizowanego w ramach grantu KPO dla Kultury sfinansowanego przez Unię Europejską NextGenerationEU Zapraszamy również do obejrzenia pozostałych nagrań z tego cyklu: Po co nam miedze, drzewa i krzaki? - Paweł Średziński - https://youtube.com/live/Mpc8jUXzA4k O stawie i angażowaniu mieszkańców - Maciej Jędrzejczak - https://youtube.com/live/QwdOWvFFC1s Znajdź nas: https://www.youtube.com/c/WszechnicaFWW/ https://www.facebook.com/WszechnicaFWW1/ https://anchor.fm/wszechnicaorgpl---historia https://anchor.fm/wszechnica-fww-nauka https://wszechnica.org.pl/ #nextgenerationeu #kpodlakultury #bioróżnorodność #kultura #dziedzictwo #wieś #polskawieś #przyroda #KPOdlakultury #KPO #krajoznawcy #krajoznawstwo

ASX 200 jumped 61 points to 8344 (+0.7%) as resources back in vogue. China cut rates today, iron ore futures rallied slightly. BHP up 1.4% on Samarco update, RIO up 1.9% and FMG rallying 1.5%. Gold miners in demand again, NST up 1.9% and EVN shooting higher, up 5.2%. Lithium stocks also seeing short covering, PLS up 3.4% and MIN suffering badly on CEO and tax issue news, down 13.8%. Oil and gas stocks better with WDS up 1.3% and STO rallying 1.5% with uranium stocks glowing, BOE up 6.2% and PDN up 4.2%. Industrials firmed, WES up 1.4% and ALL up 1.5% with retail under some pressure, LOV down 6.4% and SUL off 1.5%. A slight recovery in Travel stocks, FLT up 0.6% and WEB rallying 2.1%. Banks were solid again with the Big Bank Basket up to $247.89 (0.8%). Insurers better, QBE up 1.2% and MQG doing well today. Healthcare and REITs also doing well. In corporate news, WTC dominated as the CEO issues spread from the front page to the business page. It fell hard by 14.6%. NCK warned on freight costs dropping 4.1%. Quarterlies continue to drop with S32 down 0.3% on manganese shortfall. Nothing locally on the economic front, China saw some rate cuts to prime lending rates. Asian markets mixed, HK down 0.6%, China up 0.9% and Japan up 0.3%. 10-year yields 4.28% easing slightly. Why not sign up for a free trial? Get access to expert market insights and manage your investments with confidence. Ready to invest in yourself? Join the Marcus Today community. 

S&P 500 rose 0.25%, closing the session with its 41st record close for the year. The Dow too notched a record close, up 84 points (+0.20%). Up 156 points at best. Down 68 points at worst. NASDAQ advanced 0.56%, while mega-cap tech stocks were mixed. Nvidia jumped 4.0%, while Microsoft and Meta eased 1.0% and 0.2% respectively. Markets shrugged off US consumer confidence data, despite falling to 98.7 in September dropping the most in three years from an upwardly revised 105.6 in August. Treasury yields slipped in choppy trading. 2Y yield fell 4.7bps pressured by a 2Y auction, and the 10Y yield fell 1.9bps to 3.732%. Steep Yuan inflows have pushed the Chinese Yuan to hit a 16-month high, resulting in broad USD selling USD Index down 0.48%, while also propping up HK +4.13% and Chinese +4.15% equity markets.ASX to rise. SPI Futures up 25 points (+0.30%). On the calendar today, Australian CPI data at 11:30am. AGL and RED hosting AGM's. SIG, SOL and PMV releasing earnings reports and CWP, IMD and NCK are trading ex-dividend today.Why not sign up for a free trial? Get access to expert market insights and manage your investments with confidence. Ready to invest in yourself? Join the Marcus Today community. 

ASX 200 closes up 96 points to 7777 (+1.2%) still down 2% for the week. Resources took up the baton in the ‘repechage'. Gains in iron ore in Singapore brought buyers back in. BHP up 1.6%, and RIO up 2.0%. Lithium stocks also bounced, with PLS doing well, up 3.0%, as MIN rallied 1.5% and S32 up 3.9%. Gold miners bounced back, NST up 1.2%, and WAF up 6.8% after a baton drop yesterday. Oil and gas better too as WDS bounced 2.3%, with uranium stocks slightly firmer, clean out of the blocks this morning. Banks ran a solid race through to the semis, with ANZ up 1.1% and WBC up 0.7%, with the Big Bank Basket up to $221.19 (+0.6%). Insurers firmed, with the exception of QBE, which had a false start and disappointed selectors. Other financials pushed higher, with MQG up 1.0% and ASX up %. REITS on the podium, GMG up 3.2%, and GPT pushing 1.8% ahead. Good moves from REA and CAR, results from NWS too helping, tech better, WTC up 2.7% and XRO running a PB up 2.6%. The All-Tech Index up 3.2%. Retailers were mixed as NCK rose 0.1% on results, and Travel stocks failed at the new height losing a little. Healthcare stocks rose to the challenge and hopped skipped, and jumped higher, COH up 2.4% and SHL ahead by 0.7%. In corporate news, QBE fell 1.7% on results, NWS and REA delivered. NEU failed a drug test and slipped 5.5% on trial results. Nothing locally on the economic front, Chinese CPI rose. A promising sign for consumerism. Asian markets settled mixed, with Japan up 0.9%, HK up 1.4% and China unchanged. 10-year yields steady at 4.07%. Why not sign up for a free trial? Get access to expert market insights and manage your investments with confidence. Ready to invest in yourself? Join the Marcus Today community.

The Ireland Boys discuss the Trump Rally, Country Music, and Trump Vs. Biden! Special Guest IBD brings up his opinion on the boy's new country song and the political state of the United States. NCK has also dropped a new song, "After. You won't want to miss this pod! OUR NEW COUNTRY SONG

The Ireland Boys discuss Sketch and his secret, N3on getting Jumped, and the White Party! Matthew JGL brings up the past drama with Jack Doherty and The Jeff Whiteck controversy. NCK has recently released a new song called "Halo." Don't miss out on this podcast! NCK's New Song

The Ireland Boys discuss Neon Vs. Jack, Ryan Garcia's Ban, and the impact of social media on society! Ricky, Nick, and Leo discuss the hawk tua incident and why social media hurts the younger generation. NCK has recently released a new song called "Halo." Don't miss out on this podcast! NCK's New Song

Ireland Boys discuss their video ideas, new music, and the contrast between country and rap songs! Mason Lamb mentions the "Mr. Beast effect," highlighting new creators. NCK has recently released a new song called "Halo." Don't miss out on this podcast! #itiswhatitis #itiswhatitispodcast #irelandboys #podcast NCK's New Song

The Ireland Boys discuss Logan Paul Vs. Bradley Martin, exposing NASA & SpaceX, and expecting the unexpected! Ricky and Nick expose the Hollywood film industry mentioning how they are trying to control society. NCK has recently released a new song called "Halo." Don't miss out on this podcast! #itiswhatitis #itiswhatitispodcast #irelandboys #podcast NCK's New Song

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This week we're talking to Matt Walker about his regression testing system, Stock Doctor's continuing data quality issues, NCK's UK expansion, HMC Capital takes aim at GNC, fudging DUR and LAU, and get some insider information about Austal Ships.

USE CODE IBP for 40% off your 1st Order at https://https://www.flexpromeals.com/menu/?coupon_code=IBP (https://www.flexpromeals.com/menu/?coupon_code=IBP) The Ireland Boys discuss Red Flags in relationships, Haney Vs. Garcia and The Word Of God! DJ Faboloso brings up the Tupac X Drake X Snoop Dog beef with Kendrick. NCK has also dropped a new song, "Bad Bluffing". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link WATCH ON: YOUTUBE: https://youtu.be/wT5F3C__cIw An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss how they got fined $10,000, what parent they feel connected to the most and answer fan questions! DJ Faboloso brings up how he almost went to jail pt - 15. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! USE CODE IBP for 40% off your 1st Order at https://https://www.flexpromeals.com/menu/?coupon_code=IBP (https://www.flexpromeals.com/menu/?coupon_code=IBP) OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: SPOTIFY: https://open.spotify.com/show/6og3T6xtDQnAksZzIxJNoI?si=KxC1f4J_SFa0h5vkhYJYZw An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss hitting 200,000 subscribers, Ricky and DJ Faboloso's internal beef, and Drake's rap scene beef! DJ Faboloso brings up his ideology on having multiple wives. NCK has also dropped a new song, "Bad Bluffing". You won't want to miss this pod! USE CODE IBP for 40% off your 1st Order at https://https://www.flexpromeals.com/menu/?coupon_code=IBP (https://www.flexpromeals.com/menu/?coupon_code=IBP) OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link BAD BLUFFING ► https://lnkfi.re/BadBluffing LISTEN ON: SPOTIFY: https://open.spotify.com/show/6og3T6xtDQnAksZzIxJNoI?si=KxC1f4J_SFa0h5vkhYJYZw An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

#itiswhatitis #itiswhatitispodcast #irelandboys #irelandboysproductions In this podcast, the Ireland Boys share their thoughts on Sketch and Jynxzi, We Don't Trust Your Beef, and How to Rizz! Ricky talks about feeling more present after taking a trip and taking on more adult responsibilities. Meanwhile, NCK talks about the difference between friendships and relationships while explaining how to "rizz." Make sure to tune in and don't miss out! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link WATCH ON: YOUTUBE: https://youtu.be/UGNVq8qW8js An inside look into the behind-the-scenes life of the Ireland Boys, Ricky and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

#itiswhatitis #itiswhatitispodcast #irelandboys #IBP #RickyIreland #NickIreland #DJFAB #DJFaboloso The Ireland Boys discuss Mr. Beast's $100 million game show, the Jack Doherty allegations, and Miami's nightlife. DJ Fab mentioned his recent flight experience in which the plane had to make an emergency landing during the journey You won't want to miss this pod! NCK will be releasing his new song titled "Bad Bluffing" on April 5th. OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link Watch ON: YOUTUBE: https://www.youtube.com/@itiswhatitispodcast1 An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before…

#itiswhatitis #itiswhatitispodcast #irelandboys #IBP #RickyIreland #NickIreland #DJFAB #DJFaboloso The Ireland Boys discuss the social media industry, Jack Doherty, and how money and fame can lead to greed. Matthewjgl exposes the life bad business that Austing Mcbroom does and exposes Jack Doherty's lifestyle. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link Watch ON: YOUTUBE: hhttps://youtu.be/WdkcLeIbth0 An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before…

#itiswhatitis #itiswhatitispodcast #irelandboys #IBP #RickyIreland #NickIreland #DJFAB #DJFaboloso The Ireland Boys discuss Jake Pauls's next opponent, Mr.Beast selling his channel to Disney, and Ryan Garcia spiraling out of control. DJ Fab brings up how he almost got arrested last week and was wanted by the police. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link Watch ON: YOUTUBE: https://www.youtube.com/@itiswhatitispodcast1 An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before…

#itiswhatitis #itiswhatitispodcast #irelandboys #IBP #RickyIreland #NickIreland #DJFAB #DJFaboloso The Ireland Boys discuss the importance of loyalty in relationships, the popularity of The Weekend's music, and the controversy surrounding Brawadis. DJ Fab encourages you to pursue your dreams without allowing anyone to discourage you. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link Watch ON: YOUTUBE: https://youtu.be/Jla1RB2mkcQ An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

#itiswhatitis #itiswhatitispodcast #irelandboys #IBP #RickyIreland #NickIreland #DJFAB #DJFaboloso The Ireland Boys discuss Ricky getting JUMPED, going to the club, and NCK's Valentine's Day. DJ Fab brings up the reality of being with a good crowd. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link Watch ON: YOUTUBE: https://youtu.be/Jla1RB2mkcQ An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

#itiswhatitis #itiswhatitispodcast #irelandboys #vitaly #Nick Nayersina #adinross #santi #howtocatchapredator #predator #chrishansen The Ireland Boys discuss the Chief's Super Bowl win, finding a girlfriend, and special guest Mehdi's advice on self-improvement. DJ Fab brings up the reality of finding your true love and his dating horror stories. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link Watch ON: YOUTUBE: https://youtu.be/Jla1RB2mkcQ An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

#itiswhatitis #itiswhatitispodcast #irelandboys #vitaly #Nick Nayersina #adinross #santi #howtocatchapredator #predator #chrishansen The Ireland Boys discuss Adian Ross, Vitaly, and special guest SANTI catching predators on YouTube and Kick. DJ Fab and Santi bring up the harsh reality of the world and why people need to be stopped. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: SPOTIFY: https://open.spotify.com/show/6og3T6xtDQnAksZzIxJNoI?si=KxC1f4J_SFa0h5vkhYJYZw An inside look into the behind the scenes life of the Ireland Boys, Ricky and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss N3on's breakup, and Sam Frankin's relationship, and break down how Mr.Health Benefits is doing. DJ Faboloso and Mason Lamb cook up a crazy new Hide and Seek idea never seen before. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! http://Sleeper.com/promo/IBP CODE - IBP & DEPOSIT $10 NCK - New Years Freestyle ► https://lnkfi.re/NewYearsFreestyle OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link WATCH ON: YOUTUBE: https://youtu.be/oi83GO52bVE An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss Jack Doherty being Fake, Neon and Sam Frankin's relationship, and the entire social media industry is FAKE! DJ Faboloso brings up the Mr.Beast formula which brings new creators to the spotlight. NCK has also dropped a new song, "New Year's Freestyle". You won't want to miss this pod! NCK - New Years Freestyle ► https://lnkfi.re/NewYearsFreestyle NCK - Cold Again (Official Music Video) ► https://youtu.be/sQ4JMtyOrlo?si=qcWcCYt0s1h484dX OUR MERCH ► https://ibpmerch.com/products/24-hr-overnight-szn-2 SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link WATCH ON: YOUTUBE: https://youtu.be/vqussGqPXXs An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss Neon and Sam, Austin McBroom's Divorce, and why Vitaly is heading down a bad path. DJ Faboloso calls out King Vitaly to box and mentions he would knock him out cold. NCK has also dropped a new song, "New Years Freestyle". You won't want to miss this pod! NCK - New Years Freestyle ► https://lnkfi.re/NewYearsFreestyle NCK - Cold Again (Official Music Video) ► https://youtu.be/sQ4JMtyOrlo?si=qcWcCYt0s1h484dX OUR MERCH ► https://ibpmerch.com/products/24-hr-overnight-szn-2 SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: SPOTIFY: https://open.spotify.com/show/6og3T6xtDQnAksZzIxJNoI?si=KxC1f4J_SFa0h5vkhYJYZw An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss Overnight in an Underwater Hotel, their Overnight Marathon, and eating a 24-carat burger. DJFaboloso brings two special guests onto the podcast and talks about fighting Jake Paul for his first pro boxing match. NCK has also dropped a new music video, "Cold Again". You won't want to miss this pod! NCK - Cold Again (Official Music Video) ► https://youtu.be/sQ4JMtyOrlo?si=qcWcCYt0s1h484dX OUR MERCH ► https://ibpmerch.com/products/24-hr-overnight-szn-2 SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: SPOTIFY: https://open.spotify.com/show/6og3T6xtDQnAksZzIxJNoI?si=KxC1f4J_SFa0h5vkhYJYZw An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss Fousey's return to streaming, Mr. Beast being canceled, and their next overnight video. NCK brings up the Jack Doherty Halloween fight and how a ghost follows him. Ireland Boys Have also dropped a new "NCK - EMBROIDERED Heavyweight Cotton Hoodie". You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: YOUTUBE: https://youtu.be/sqIhLwyejf8 An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before…

OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link The Ireland Boys discusses how NCK got catfished, Taylor Swift dating Travis Kelce and Dating. DJ Fabolous brings up why Rick looked at him when he said "BIG BOYS", his old club life stories, and having meat and greets. Ireland Boys Have also dropped a new "NCK - EMBROIDERED Heavyweight Cotton Hoodie". You won't want to miss this pod! WATCH ON: YOUTUBE: https://www.youtube.com/@itiswhatitispodcast1/videos An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before…

Fitch downgrades the US, Lowe has new ideas about the RBA, NCK beats the pulled pork curse, MYR rebounds, iron ore falls (every October?), Baby Bunting pulled pork, and problems with Updater's delisting.

The market's had a rough week, MYR collapses on good results, business confidence is up while consumer confidence is down, coking coal isn't a sell after all, pulled pork on NCK, possible changes to Rule 1, BBN's performance, and adding buybacks to the checklist.

The Ireland Boys talk about Elon Musk vs. Mark Zuckerberg, the submarine that imploded, and hitting their first 100K scribers. Ricky and NCK also brought on some special guests to test them for the third co-host spot. You won't want to miss this pod! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: SPOTIFY: https://open.spotify.com/show/6og3T6xtDQnAksZzIxJNoI?si=KxC1f4J_SFa0h5vkhYJYZw An inside look into the behind the scenes life of the Ireland Boys, Ricky and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys talk about firing D JFaboloso, Al Pacino, and the new third Co-Host. Ricky and NCK drop a few fun facts of the week, new laws in Japan, and a man who faked his death. You won't want to miss this podcast episode! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: https://youtu.be/LS1dmUGwpLQ An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys talk about UFOs, Apple Vision Pro, and the Apple Vision Pro. Ricky, Dj Fabolouso, and NCK get into a head argument leading to them getting canceled. You won't want to miss this podcast episode! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: https://youtu.be/TBnNyFiNhZs An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

Ça y est : voici venu le moment que vous attendiez toustes ! On va enfin parler d'Hugo Clément et poser les termes du débat : était-ce une bonne idée d'aller à Valeurs actuelles au nom de l'animalisme et de l'écologie ?  On n'a pas voulu prétendre clore le débat avec mon invité, mais plutôt envisager les différents arguments en informant sur les risques et les implications de la présence d'une figure médiatique écologiste dans un tel événement, et les éléments qu'il est bon de prendre en compte lorsqu'on est invité-e par des médias d'extrême-droite.  Je pense qu'une grande partie des réflexions de cet épisode vis-à-vis de l'écologie peuvent aussi s'appliquer à l'animalisme, car il y a des enjeux communs. Notamment faut-il formuler le sujet de société de l'écologie ou de l'animalisme de façon transpartisane, voire apolitique, pour s'adresser à davantage de personnes, ou plutôt rechercher la clarification idéologique d'un projet de société articulé aux autres enjeux contemporains et s'inscrivant sans ambiguïté du côté des luttes d'émancipation ?  ________________________________ Références et sources citées dans l'entretien :  - La série de podcast en 3 parties "La banalisation médiatique de l'extrême droite" sur la plateforme Spectre : https://spectremedia.org/podcast/la-banalisation-mediatique-de-lextreme-droite-partie-1/?episode=716 - L'article "Médias et extrême droite : la grande banalisation" sur le site d'Acrimed : https://www.acrimed.org/Medias-et-extreme-droite-la-grande-banalisation?recherche=dédiabolisation - « La décroissance, ce journal que nous n'achèterons pas » sur RebelLyon : https://rebellyon.info/La-decroissance-ce-journal-que-nous-n-20957 - Le collectif Cabrioles (Carnet de recherche pour l'Autodéfense Sanitaire face au Covid-19) : https://cabrioles.noblogs.org - L'article "La naturalisation comme dépolitisation de la pandémie" sur le blog d'Antoine Dubiau Perspectives printanières : https://perspectives-printanieres.info/la-naturalisation-comme-depolitisation-de-la-pandemie/ - La tentation écofasciste - Pierre Madelin Recommandations d'Antoine Dubiau : - Le podcast Minuit dans le siècle, animé par le sociologue Ugo Palheta et diffusé sur la plateforme spectre : https://spectremedia.org/minuit-dans-le-siecle/ - La chaîne Youtube @GameOfHearth, qui parle d'écologie politique et de féminisme : https://www.youtube.com/@GameOfHearth/featured - Les écrits d'écologie politique de Murray Bookchin ________________________________ SOUTENIR : https://linktr.ee/poissonpodcast Comme un poisson dans l'eau est un podcast indépendant et sans publicité : votre soutien est indispensable pour qu'il puisse continuer à exister. Merci d'avance ! Les comptes Instagram, Twitter, Facebook et Mastodon du podcast sont également à retrouver dans le link tree ! ________________________________ CRÉDITS Comme un poisson dans l'eau est un podcast indépendant créé et animé par Victor Duran-Le Peuch. Charte graphique : Ivan Ocaña Générique : Synthwave Vibe par Meydän Musique :  To Be Free par Nck

The Ireland Boys discuss getting back from Miami, new pranks, and stealing another man's WIFE. The boys give their fans insight into their favorite videos and NCK gives an update on his weekly dates. You won't want to miss this podcast episode! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: YOUTUBE: https://youtu.be/sj_FqLDHfbA An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

The Ireland Boys discuss getting ROBBED IN MIAMI and at the same time, losing Computers, and Cameras. NCK talks about his upcoming date and how to be yourself so that you won't care about the negativity others speak about you. You won't want to miss this podcast episode! OUR MERCH ► https://ibpmerch.com/ SUBSCRIBE TO THE CLIPS CHANNEL ► https://www.youtube.com/channel/UClrqvGRTrRh0D-z83dO3C_g FOLLOW ON INSTAGRAM ► https://www.instagram.com/itiswhatitis._podcast/?utm_medium=copy_link LISTEN ON: YOUTUBE: https://youtu.be/BfOo6KyP6aY An inside look into the behind-the-scenes life of the Ireland Boys, Ricky, and Nick Ireland, and their CRAZY stories, experiences, and adventures that have never been told on camera before… Business Inquiries: IrelandBoysPodcast@gmail.com

After a deadly fight in a back alley of The Bureau, the Meatsacks set their sights on Bonerland. Without a heading, they make their way to Substance, a popular nightclub in the city where they might get information about the next finger. From there, it's a wild series of unfortunate events in the most pleasurable part of the Wen. Lord Wolf dances it out, Rat Duke misreads a situation, and The King Brothers feel the heat, this week on The Rolled Standard. Check out our various socials and whatnot at: https://linktr.ee/therolledstandard We have a Patreon. Check it out here: https://www.patreon.com/therolledstandard The Rolled Standard is: Christopher Heinrich as Mayor King @7CannibalChris7 Levi Brusacoram as Lord Wolf @LeviBoozy Jake Vaughn as Rat Duke @vaughnhaus Nate Seibert as King Mutt @TheRolledNate And featuring Walton Wood as the Game Master @LiberLudorum Pieces of Eden was written by Walton Wood. Episode edited by Jake Vaughn and Nate Seibert. Cover art by Cannibal Chris. Theme music: Machine Gun by Infraction Substance background music: The Rooftop Club by Le Gang, Replicant World by Mike Chino, To Be Free by NCK, Hustle by Peyruis, and Rogue by Sybranax. Huge thanks to Walton Wood, Strega Wolf van den Berg @strega_flora, The Bogfolk Cafe, and Derek Gustafson @DeGustafson. --- Support this podcast: https://anchor.fm/therolledstandard/support

Portfolio Updates, commodity updates , NCM takeover, WHC coal breakdown, RBA to lift rates, the FOMO rally, Pulled Pork on NCK, R1 trigger on commodities, a tighter sell line for MYR, What time of day does TK buy and sell, fudging AMP's sell line, penny stocks and Rule 1, WDS commodity breakdown, and After Hours (which you don't have to listen to if you don't want to!).

SponsorsGorilla BBQ - http://www.gorillabbq.comExtra Kart Parts - https://ebay.us/RDIEVGThank the clubs and promoters who support Norcal Karters and the Promotion of KartingChallenge of the AmericasSonoma Rok CupNCK Road RacersPrairie City KartingSponsorsGorilla BBQExtra Kart Parts“If we all bring 1 person into the sport this year, we will double our size”Quick Links Norcal Karters on Youtube - https://www.youtube.com/c/NorcalKarters/featuredNorcal Karters on Facebook - https://www.facebook.com/norcalkartersNorcal Karters on Instagram - https://www.instagram.com/norcalkarters/Donate to Norcal Karters - https://www.paypal.com/paypalme/norcalkarters

NCK got a tattoo and had a predicament with some girls.