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July 16, 2025. Week 29. What is a natural history study (NHS)? And why do we care? We care because we haven't done this before, heal those born with disease. Natural history studies, which examine the progression of a disease over time, can be either retrospective or prospective. Retrospective studies analyze existing data, like medical records, while prospective studies collect new data over time. Both types are valuable for understanding a disease's course and informing research and treatment strategies. NHS are critical for clinical trial design. Size and Quality matter. Validated scales are better than PROs regardless of what the current rhetoric is. What's going on now? USA - https://curesyngap1.org/resources/studies/syngap1-ProMMiS/ - 135+ over three sites, some with FOUR visits, and counting - Adding GCP - Collaborating with world class institutions and excellent clinicians at Stanford, Children's Colorado and, of course, CHOP. USA - https://Citizen.Health/partners/srf has almost 300 patients! Retrospective Health Data. USA - https://rare-x.org/syngap1/ is where we collect PROs. Australia - Dr. Sheffer is running a study, talk to her or Dani. Latin America - SYNGAP1 Argentina with others joining. Europe - https://www.patre.info/syngap1/ Key takeaways for Industry SYNGAP1 is well positioned to work with… Vlasskamp and Wiltrout are published, Citizen Health is growing & ProMMiS is truly exceptional – and growing, and Rare-X is collecting eight key PROs. Additionally, there are significant international efforts in Australia, Latin America & Europe. Census: https://curesyngap1.org/blog/syngap1-census-2025-update-55-in-q2-2025-total-1636/ If you are in industry and thinking about starting another NHS for your asset, please don't. Please instead partner with existing PAGs and NHS studies in your key geographies to move faster, have bigger N and not waste precious patients time, we need to accelerate drug development not slow it down by diluting patients and clinicians between too many studies. Baseline papers on SYNGAP1: 1998 - Huganir - SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family - https://pubmed.ncbi.nlm.nih.gov/9581761/ 2009 - Michaud - Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation - https://pubmed.ncbi.nlm.nih.gov/19196676/ 2013 - Carvill - Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1 - https://pubmed.ncbi.nlm.nih.gov/23708187/ 2019 - Vlasskamp - SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy - https://pubmed.ncbi.nlm.nih.gov/30541864/ 2023 - Rong - Adult Phenotype of SYNGAP1-DEE - https://pubmed.ncbi.nlm.nih.gov/38045990/ 2024 - Wiltrout - Comprehensive phenotypes of patients with SYNGAP1-related disorder reveals high rates of epilepsy and autism - https://pubmed.ncbi.nlm.nih.gov/38470175/ Pubmed is at 28 (so less than one a week…) https://pubmed.ncbi.nlm.nih.gov/?term=syngap1&filter=years.2025-2025&timeline=expanded&sort=date&sort_order=asc CURE SYNGAP1 CONNECT https://curesyngap1.org/curesyngap1connect/ SHARE BLOOD TO THE SRF BIOBANK AT CB! Read here for more information: https://curesyngap1.org/blog/fueling-research-syngap1-combinedbrain-biorepository-roadshow/ VOLUNTEER Join us: https://curesyngap1.org/volunteer-with-srf/ SOCIAL MATTERS - 4,238 LinkedIn. https://www.linkedin.com/company/curesyngap1/ - 1,400 followers with 575 Videos on YouTube. https://www.youtube.com/@CureSYNGAP1 - 11,302 Twitter https://twitter.com/cureSYNGAP1 - 46k Insta https://www.instagram.com/curesyngap1/ NEWLY DIAGNOSED? New families have resources here! https://syngap.fund/Resources Podcasts, give all of these a five star review! https://cureSYNGAP1.org/SRFApple https://podcasts.apple.com/us/channel/syngap1-podcasts-by-srf/id6464522917 Episode 175 of #Syngap10 #RareDisease #PatientAdvocacy #SYNGAP1 #SynGAP #ProMMiS
Pags breaks down breaking news out of Alaska after a powerful earthquake shakes the state—what we know, what's still unfolding, and what officials are saying. Then, are paid protestors and actors finally being exposed? Pags dives into shocking new developments and evidence that might just prove the rumors true. PLUS—Senator James Lankford joins Pags for a deep dive into the Big Beautiful Bill, America's energy independence, and why reclaiming our own natural resources matters more than ever. Lankford also clears up major misconceptions about “rescission” and what it actually means for the budget and the American taxpayer. A packed, informative, and can't-miss episode! Learn more about your ad choices. Visit megaphone.fm/adchoices
Why does everyone online act like the world revolves around them? Pags tackles the rise of “Keyboard Kenny”—those overly sensitive, chronically online users who insert themselves into every conversation. It's a wild social media shift you've probably seen firsthand. Then, Pags is joined by the incredible Ali Bradley for a must-hear update on the southern border. What's really happening on the ground? Who's coming in—and what's being done about it? From digital drama to real-world consequences, this hour delivers the commentary and clarity you need. Learn more about your ad choices. Visit megaphone.fm/adchoices
Who's really on the Epstein client list—and is there even an official list? Pags dives deep into the latest revelations, breaks down what we do and don'tknow, and explains what President Trump just said on the record about the Epstein situation. With headlines swirling and misinformation spreading fast, Pags lays out the facts, the speculation, and the silence from legacy media. If you're confused, curious, or just want the truth—this is the segment you need to hear. Full breakdown, no fluff. Learn more about your ad choices. Visit megaphone.fm/adchoices
Is AOC about to face a defamation lawsuit? Pags breaks down the stunning details in a fiery segment that could have major legal consequences. Then, Rep. Lisa McClain joins to discuss the Big Beautiful Bill, the rising attacks on ICE agents, and the chilling one-year anniversary of the Trump assassination attempt. What questions remain unanswered — and why isn't the media asking them? Don't miss this explosive conversation packed with truth, accountability, and big takeaways. Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump shocks reporters on his way to Pennsylvania with an off-the-cuff comment about Vladimir Putin that has everyone talking—Pags breaks it down with full context and a side of jaw-dropping reaction. Plus, where does Ukraine stand nearly four years into the war? And don't miss the exclusive conversation with Jewish News Syndicate Editor-in-Chief Jonathan Tobin as he unpacks the fragile ceasefire between Israel and Iran, what led to it, and what could come next. This hour is packed with breaking takes and must-hear analysis! Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags unloads on the stunning hypocrisy of Democrat leaders who skipped town during the worst of the Texas flood disaster—only to show up weeks later crying racism. When President Trump visited Kerrville, Texas, Republican leaders were there immediately—offering help and showing unity. But where were the Democrats? Pags isn't holding back as he lays out the timeline, the facts, and the double standards in this fiery segment you don't want to miss. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags lightens things up with a fun dive into the new Superman movie and the backlash it's getting from MAGA voices calling it “woke.” But hold on—Pags and Polo say not so fast! They break down why this film might not deserve the hate, and you'll want to hear their laid-back, entertaining take on it all. PLUS—Kay Hill joins the conversation and things get fiery! From LA's homeless crisis and Mayor Karen Bass funneling cash to illegal immigrants, to whether pastors should endorse political candidates—Pags and Kay go there. You won't want to miss this bold, engaging hour! Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump lays out a bold plan to sell weapons through NATO to support Ukraine—finally, a pro-America way to aid our allies without draining our own resources. Pags dives in full force, breaking down why this strategy might just flip the narrative. AND—Dr. Simone Gold joins to expose how government overreach during the pandemic crushed medical freedom. Her new tell-all book pulls no punches, and this conversation reveals just how far the authorities went to control what we put in our bodies. You need to hear this. Learn more about your ad choices. Visit megaphone.fm/adchoices
Nearly a year since the attempted assassination of Donald Trump in Butler, PA, the now-President breaks his silence in a raw, emotional speech at a prayer lunch with business leaders. Pags brings you every must-hear clip—plus his full breakdown of what Trump said, how the country responded, and why this moment matters more than ever in 2025. From media coverups to public awakening, this is a powerful hour you won't forget. Learn more about your ad choices. Visit megaphone.fm/adchoices
OneLegUpAlex Previews MLB All Star Game With Pags Perspective Host Ryan Pagano 7-15-25You can find Pags Perspective's episodes HERE: https://www.spreaker.com/podcast/pags-perspective--6149401
OneLegUpAlex Previews MLB All Star Game With Pags Perspective Host Ryan Pagano 7-15-25You can find Pags Perspective's episodes HERE: https://www.spreaker.com/podcast/pags-perspective--6149401
Pags digs deep into the 14th Amendment and what it really says about birthright citizenship. He cuts through the noise to arm you with the truth—perfect for sharing with friends and family who've been misled. Then, expert on China Gordon Chang joins Pags to reveal what he believes are China's dangerous, long-term plans for America and the world. You don't want to miss this powerful, eye-opening interview! Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags covers it all— DHS Secretary Kristi Noem calls out CNN for their blatant bias and “fake news” spin, and you won't believe what she said. Then, Congresswoman Beth Van Duyne joins Pags to address the devastating Texas flooding in the Hill Country. From emergency response to what happens next for families in crisis, this conversation is full of raw truth and leadership in action. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags delivers the must-hear breakdown of the deadly flooding in Kerrville, Texas—with harrowing updates, rescue details, and firsthand reports. Plus, Texas Rep. Tony Gonzales drops breaking news as he moves to officially honor a flood hero who saved nearly 200 lives. And don't miss the eye-opening contrast Pags reveals between states that support ICE and those that shield criminal illegal aliens through sanctuary policies. This hour is packed with truth, drama, and the kind of bold reporting you won't get anywhere else. Learn more about your ad choices. Visit megaphone.fm/adchoices
Dr. Kevin O'Connor, President Biden's longtime physician, pleaded the Fifth and cited HIPAA protections during a closed-door House hearing—refusing to answer questions about Biden's cognitive health and who's really making decisions behind the scenes. Pags dives in: should a sitting president even have HIPAA protections? Shouldn't Americans know the truth about their leader's health? Pags asks the questions legacy media won't touch. Plus—Rep. Dale Strong joins the show to talk about the Texas flood disaster, what he's seen on the ground, and how Congress plans to respond to this ongoing crisis. A must-hear episode filled with hard questions, urgent updates, and real answers. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags reports on the devastating flooding up near Kerr County: over 109 confirmed dead and more than 150 still missing, with rescue teams battling dangerous conditions to find survivors. Then, President Trump hosted a multilateral lunch in DC with five West and Central African leaders—Senegal, Liberia, Guinea-Bissau, Mauritania, and Gabon—to shift U.S. policy from aid to mutual trade and investment. In a candid press moment, Trump even questioned whether recent attacks on ICE and CBP agents might be part of an “organized threat.” Pags breaks down both the human tragedy in Texas and the high-stakes diplomatic shift—and he's got the clips you need to hear. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags dives into reports that former intel heads John Brennan and James Comey are now under investigation—but he's not jumping on the bandwagon just yet. With his trademark skepticism, Pags breaks down what we know, what we don't, and why timing matters. Plus, shocking accusations are surfacing against Austin's fire chief in the wake of the devastating Texas floods—you won't believe what he's being blamed for. And finally, “America's Pastor” Max Lucado joins Pags to offer a powerful message of hope, healing, and faith as Texans begin to pick up the pieces. Learn more about your ad choices. Visit megaphone.fm/adchoices
ICE raids are ramping up across the U.S., targeting violent offenders—but some of the arrests are raising questions. Tom Homan joins Pags live to reveal the truth: many of these so-called “casualty arrests” are the direct result of sanctuary cities refusing to cooperate with ICE. Homan pulls no punches, naming names, exposing failures, and laying out why these cities are putting Americans at risk. If you want the real story—not the headlines—this is it. Learn more about your ad choices. Visit megaphone.fm/adchoices
FBI whistleblower Kyle Seraphin joins Pags in “rare full rabbit-hole mode” to tear into the Jeffrey Epstein saga—covering the murky client list, the prison suicide, and that missing minute of jail footage that has everyone freaking out. Seraphin, a former FBI agent turned civil‑liberties crusader, says the public release of this data isn't adding up and raises tough questions: why now? What are they hiding? Why are files being deleted? Pags and Seraphin dig into every dark corner—from conspiracy to cover-up—in a must-hear, fact‑filled breakdown that cuts through the spin. Don't miss the truth you can't get anywhere else. Learn more about your ad choices. Visit megaphone.fm/adchoices
Historic flooding in Central Texas has devastated communities, with over 109 confirmed dead and more than 160 still missing. Kerr, Travis, and Kendall counties remain in crisis as rescue crews, the Texas National Guard, FEMA, and volunteers from across the U.S. and Mexico work around the clock to find survivors. Listeners call in with emotional first-hand accounts from the ground in Kerrville, describing rising waters and desperate rescue efforts. Lt. Gov. Dan Patrick joins Pags to share his personal experience—he was acting governor when the storm hit and arrived in Kerr County within hours. Patrick breaks down the state's rapid coordination with the Trump administration, how FEMA responded immediately, and the critical need for permanent flood warning systems moving forward. It's a sobering look at leadership, resilience, and what must change before the next disaster strikes. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags reports live on catastrophic flash flooding less than an hour from his studio—rivers surged 26 feet in under an hour, leaving more than 100 dead and numerous missing across Kerr and Travis Counties. Joining him, meteorologist Chris Wartz breaks down how a stalled storm system created a deadly downpour early Friday morning—drop ins so rapid they overwhelmed highways, homes, and camps in South and Central Texas. This weekend's weather is critical for continued rescue efforts and safety warnings. Tune in as they unpack what Texas is facing now and why residents must stay alert. Learn more about your ad choices. Visit megaphone.fm/adchoices
As misinformation spreads like wildfire in the wake of Texas' devastating floods, White House Press Secretary Karoline Leavitt takes the podium andtorches the fake narratives. She dismantles media lies that blamed the Trump administration for the disaster response and backs it up with receipts—timelines, alerts, and proof the warnings were there. Pags breaks it all down, clip by clip, showing exactly who's twisting the truth and why. Then, disaster expert and columnist Kay Smythe joins the show for a deep dive into FEMA's limitations, funding shortfalls, and what really needs to change to prevent tragedies like this in the future. From outdated infrastructure to broken alert systems and ignored policy recommendations, she and Pags dig into the hard questions: who dropped the ball, who's underfunded, and what can actually be done to protect Americans next time. It's a gripping, no-fluff conversation packed with facts, frustration, and solutions. Learn more about your ad choices. Visit megaphone.fm/adchoices
An armed man ambushed a Border Patrol annex in McAllen, Texas—firing dozens of rounds in tactical gear—before federal agents killed him. One police officer and a Border Patrol employee were injured in the early-morning attack. Pags gives you the full picture, including updates from Karoline Leavitt and border czar Tom Homan blasting Democrats over their anti-ICE rhetoric fueling violence. Then, General Mike Flynn joins Pags to break down international hotspots: fallout from the Iran-Israel ceasefire, how to contain Iran's regime, and the secret moves shaping global strategy. You've got to hear this hard-hitting, beyond-the-headlines scoop. Learn more about your ad choices. Visit megaphone.fm/adchoices
With the Big Beautiful Bill now passed, Pags breaks down the biggest wins for conservatives—from stronger border security funding to tighter spending caps and critical reforms on immigration enforcement. He also takes live calls from listeners to answer America's burning questions about what's really in the bill and what it means for everyday families. Plus, Rep. Buddy Carter joins Pags to share his take on the bill's impact and what happens next in Congress. Learn more about your ad choices. Visit megaphone.fm/adchoices
The Big Beautiful Bill has officially cleared both the Senate and the House, setting the stage for a huge policy shift. Pags breaks down exactly what happens next as the legislation heads to President Trump's desk, plus shares reactions from Speaker Johnson, AOC, Hakeem Jeffries, and Trump himself. Get the inside scoop on what this means for border security, spending, and the political fireworks still to come! Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags lays out what could happen next with Trump's Big Beautiful Bill as it hits the House, explaining the path forward and what's at stake if the left's spin takes hold. He tears apart their wild claims with jaw-dropping clips that show exactly how far they'll go to twist the narrative—this is a difference you have to hear. Plus, Mike Davis from the Article III Project joins to break down the latest SCOTUS decisions, including a huge win for the Trump administration on deportations and a key ruling tied to birthright citizenship. Don't miss this power-packed hour! Learn more about your ad choices. Visit megaphone.fm/adchoices
Waffle House just dropped its 50-cent egg surcharge—no more global bird-flu tax at the griddle. Pags says this signals egg prices are finally cooling and he's breaking down why this matters for your breakfast tab. Meanwhile, independent journalist Breanna Morello joins Pags to dissect the explosive Diddy verdict—what charges are sticking, what's deadlocked, and why this celebutante case is more than just gossip Learn more about your ad choices. Visit megaphone.fm/adchoices
CBS's parent, Paramount, just agreed to pay over eight figures—$16 million upfront, possibly more—to settle Trump's defamation lawsuit over a“60 Minutes” Kamala Harris interview. Pags unpacks what that really means for press freedom and meets the new “Trump Rule” requiring full interview transcripts. Meanwhile, ICE is delivering on federal promises by detaining the most dangerous illegal entrants—but Pags digs into what happens when normal people who broke immigration laws get picked up, questioning whether special circumstances should apply. It's a hard-hitting look at accountability, law, and media—all in one episode. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags dives into the grand opening of “Alligator Alcatraz” — jokingly dubbing it “Try to Leave, They'll Bite Your Ass!” — and explains why this creative, tough-on-crime idea is exactly what America needs right now. But of course, a far-left activist had to ruin the moment with a truly disgusting hot take you have to hear to believe. Pags unpacks every angle, with facts, fun, and a laugh along the way. Learn more about your ad choices. Visit megaphone.fm/adchoices
There's a harrowing update in the Idaho student murder case: Bryan Kohberger has reportedly accepted a plea deal for four consecutive life sentences, avoiding the death penalty, but the victims' families are furious—Pags shares their powerful voices demanding justice. Plus, Rep. Tony Gonzales joins to briefly outline his new PEARL Act and weigh in on what's next for Trump's Big Beautiful Bill. Learn more about your ad choices. Visit megaphone.fm/adchoices
Breaking news: Bryan Kohberger, the suspect in the University of Idaho student murders, has accepted a plea deal—he'll plead guilty to all counts, avoiding the death penalty but facing multiple life sentences. Pags rolls out the BOMBSHELL live—don't miss his take on what this means for justice. Meanwhile, President Trump weighs in on the new NYC Democratic mayoral nominee—calling him a “100% Communist Lunatic” and urging New Yorkers to wake up or risk losing federal support. Pags breaks down what President Trump really means and why this could shake things up in the Big Apple. Learn more about your ad choices. Visit megaphone.fm/adchoices
Karoline Leavitt tore into reporters at today's White House briefing, blasting them for fueling “Leak-Gate” and pushing a misleading Pentagon assessment—plus, she revealed Trump's handwritten jab at Jerome Powell for choking the economy with sky-high rates, setting off a political firestorm. Pags breaks it all down and promises the receipts! And don't miss Senator Ron Johnson joining the show to tease exactly what he likes—and seriously dislikes—about Trump's Big Beautiful Bill, with no filter. Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump is set to attend the grand opening of “Alligator Alcatraz” tomorrow, and Pags breaks down why this tough-on-crime move is a win for Americans who are sick of soft justice. Plus, Pags gets personal—sharing memories of cruising down Alligator Alley with his family and telling a hilarious story about trying an alligator burger (yes, really!). Then, Kay Hill jumps in to talk about Gavin Newsom—is he a polished Hollywood actor or an actual governor? And brace yourself—Kay even wonders if the world is on the brink of a cataclysmic event. Buckle up for this one! Learn more about your ad choices. Visit megaphone.fm/adchoices
Karoline Leavitt launches a full takedown of the far-left legacy media, accusing CNN and others of spreading misinformation about the Iran strike and demanding they “please retract” their false claims—it's a no-nonsense press briefing you've gotta hear. Then, Defense Secretary Pete Hegseth teams up with Joint Chiefs Chair Lt. Gen. Dan “Razin” Caine in a joint presser to silence the “Leak‑Gate” drama—calling the leaker politically motivated and warning they may face federal charges, as they defend a flawless Operation Midnight Hammer against false intel leaks. Pags lays out why this checks all the boxes: media mess, national security, and high-level accountability. Learn more about your ad choices. Visit megaphone.fm/adchoices
Senators were briefed on the high-stakes military mission that reportedly “obliterated” Iran's nuclear facilities—a word the media just can't stop repeating. Pags shares their reactions and cuts through the hype. Then, when a caller accuses Pags of going too hard on the left-wing media, he fires back with facts—breaking down why holding the press accountable is essential to protecting the truth. Plus, Daniel Turner joins the show to deliver exclusive insight into the future of nuclear energy in Iran vs America—this is info you won't get anywhere else. Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump takes the spotlight in the East Wing, rallying hard for his Big Beautiful Bill with powerful moments and full-throated support from Tom Homan on border security. But the headlines don't stop there—Justice Ketanji Brown Jackson is big mad, and Pags exposes exactly why. You'll want to hear this breakdown. Then—Nicole Sadighi joins Pags to uncover the truth the media ignores: the Iranian people are not their regime. She lays out the real story from the inside, and it's a game-changer. Learn more about your ad choices. Visit megaphone.fm/adchoices
(0:00) Felger, Mazz, and McCarthy open the show discussing the Celtics and the first round of last night’s NBA draft. (13:58) Would the Celtics be selling pieces off if Pags had bought the team? (27:02) The guys react to Brad Stevens’ post-draft press conference last night. (39:26) The guys discuss Brad Stevens’ comments on Joe Mazzulla’s coaching contract.
President Trump slammed New York's Democratic mayoral nominee Zohran Mamdani as a “100% Communist lunatic” after his shocking primary win—a brutal Truth Social blast that Pags, a former New Yorker himself, breaks down from the inside, including the city's culture and eats. Then, former judge and ex-Rep. Ted Poe joins the show to weigh in on the Iran–Israel ceasefire: Will we see Iranian regime change? What's next for the Iranian people? Pags and Poe dive deep on both explosive stories—you'll want this one. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags dives into the bizarre arrest of the Liver King after reports he threatened Joe Rogan—yeah, it's as wild as it sounds. Then, NATO gets awkwardly hilarious as Mark Rutte jokingly calls Trump “Daddy” during a press gaggle—Trump laughs it off, and so do we. Plus, Josh Hammer joins Pags to break down rogue judges, his recent trip to Israel, and what's really going on behind the headlines. Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump just visited NATO and doubled down on support for the U.S. military—right in the middle of “Leak‑Gate,” where a secret Pentagon intelligence assessment of recent Iran strikes was leaked to CNN. Pags explains why this leak isn't just stunning—it may be illegal, potentially exposing the leaker to federal charges. We'll hear the most explosive clips: Pete Hegseth demanding a full-on FBI probe, Karoline Leavitt defending the administration, and President Trump calling out fake news. This hour cuts through the drama and reveals what's truly at risk. Learn more about your ad choices. Visit megaphone.fm/adchoices
Rep. Alexandria Ocasio‑Cortez calls for Trump's impeachment over the Iran strikes—calling him out for allegedly violating the Constitution's War Powers—but Trump responds by mocking her as “stupid AOC” and daring Democrats to try again. Meanwhile, Kansas Sen. Roger Marshall—also an MD and U.S. Army Reserve vet—joins Pags to unpack the transparency in the administration, offer his expert take on Middle East dynamics, discuss Trump's Big Beautiful Bill (including his SHORT Act on gun rights), and preview his new gun legislation. It's a high-stakes mix of legal drama, foreign policy, and bold legislative action. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags dives into what a sleeper cell really is—a terrorist cell “lying dormant until activated” —and addresses the big question: Are there sleeper cells in America right now? With recent arrests across nine U.S. cities and DHS warnings over possible Iran-linked sleeper cells, Pags plays back clips from former ICE boss Tom Homan to cut through the panic and get to the facts. Plus—Stephen Miller goes scorched-earth on a Boston judge allegedly defying a SCOTUS order on deportations. And JNS's Ruthie Blum joins to clarify every twist and turn of the Iran-Israel ceasefire—unpacking the timeline, motives, and flashpoints you NEED to know! Learn more about your ad choices. Visit megaphone.fm/adchoices
We're witnessing a level of transparency from the White House we haven't seen in decades—so much so that cameras caught President Trumpliterally and figuratively dropping bombs. Pags unpacks the high-pressure spotlight the president lives under every day. Meanwhile, Democrat Rep. Al Green tries (and fails) to impeach Trump over the Iran strikes—only to get steamrolled by his own party. It's political drama at its finest—and Pags breaks it all down. Learn more about your ad choices. Visit megaphone.fm/adchoices
Vice President JD Vance told Fox News the Iran–Israel ceasefire marks a “reset moment” and credits Trump's diplomacy and military strength—“working the phones constantly” and targeting Iran's nuclear program while avoiding regime change. Meanwhile, Pags calls out mainstream outlets twisting the story, and brings clarity to the actual deal structure. Plus—Rep. Andy Biggs joins to unpack the BBB, weigh in on weekend strikes in Iran, and dig into what these developments mean for U.S. and Middle East strategy. Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump shocks the world with news of a ceasefire between Iran and Israel, ending what he calls the “12-Day War.” Pags breaks down this massive development and what it means for global stability. Lt Col (Ret) Jeffrey Addicott joins the show with expert insight on the Middle East, the strikes, and what happens next. Learn more about your ad choices. Visit megaphone.fm/adchoices
Pags takes aim at Hakeem Jeffries for accusing President Trump of breaking the law over a missile strike—calling out Jeffries' bizarre delivery and weak argument. Karoline Leavitt fires back with facts, blasting the left's false narrative and setting the record straight. Then, Kay Hill joins the show to unpack Gov. Greg Abbott's major veto—and why it's sending shockwaves through Texas politics. Learn more about your ad choices. Visit megaphone.fm/adchoices
President Trump speaks out on the Israel-Iran conflict with clarity, while the administration issues a firm warning to Tehran. Meanwhile, the fallout from the LA riots intensifies. VP JD Vance makes a bold statement, and DHS officials Kristi Noem and Tricia McLaughlin weigh in on what comes next. Are federal laws finally being enforced? Pags breaks it all down. Learn more about your ad choices. Visit megaphone.fm/adchoices
Michelle Obama hits the podcast circuit to complain about life—while one of her daughters reportedly ditches the Obama last name. Pags reacts to the stunning drama. AND – Rep. Troy Nehls joins the show to expose the truth about uranium enrichment, the chaos in LA, and what the Senate may do with the BBB. This interview is packed with real talk you won't hear anywhere else. Learn more about your ad choices. Visit megaphone.fm/adchoices
A shocking RAWSALERT notification sparks the question—can we trust online sources anymore? Pags breaks it all down and exposes how the left uses disinfo to stir division. Then, in a jaw-dropping move, BLM demands “white folk” pay reparations during Juneteenth events. Seriously? Pags dismantles the insanity with facts. AND—Chloe Cole joins Pags for an emotional in-person interview on her de-transition journey and why she's fighting to protect minors from gender ideology. Learn more about your ad choices. Visit megaphone.fm/adchoices