Podcast appearances and mentions of sean gibbons

Subscribe to our channel: https://www.youtube.com/@optispanGet Our Newsletter (It's Free): https://www.optispan.life/Dr. Sean Gibbons, a leading microbiome expert, sits down with me to decode the complex world of your gut bacteria. Learn about good vs. bad bacteria, the impact of antibiotics and aging, and how diet and probiotics can influence your journey to better health.0:00 - Intro: What IS Your Microbiome?7:55 - Good vs. Bad Bacteria? The Real Story14:06 - Antibiotics & Your Gut's Rebound17:31 - Aging: Your Gut's Unique Journey26:36 - Diet: Can It Truly Change Your Gut?29:46 - Microbiome Tests: Useful or Just Hype?43:44 - Probiotics: Do They Actually Work?1:10:14 - Future of Gut Health (Bugs as Drugs, Smart Toilets)Production: Nicholas Arapis, https://videocastproductions.comDISCLAIMER: The information provided on the Optispan podcast is intended solely for general educational purposes and is not meant to be, nor should it be construed as, personalized medical advice. No doctor-patient relationship is established by your use of this channel. The information and materials presented are for informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. We strongly advise that you consult with a licensed healthcare professional for all matters concerning your health, especially before undertaking any changes based on content provided by this channel. The hosts and guests on this channel are not liable for any direct, indirect, or other damages or adverse effects that may arise from the application of the information discussed. Medical knowledge is constantly evolving; therefore, the information provided should be verified against current medical standards and practices.More places to find us:Twitter: https://twitter.com/optispanpodcastTwitter: https://twitter.com/optispanTwitter: https://twitter.com/mkaeberleinLinkedin: https://www.linkedin.com/company/optispanInstagram: https://www.instagram.com/optispanpodcast/TikTok: https://www.tiktok.com/@optispanhttps://www.optispan.life/Hi, I'm Matt Kaeberlein. I spent the first few decades of my career doing scientific research into the biology of aging, trying to understand the finer details of how humans age in order to facilitate translational interventions that promote healthspan and improve quality of life. Now I want to take some of that knowledge out of the lab and into the hands of people who can really use it.On this podcast I talk about all things aging and healthspan, from supplements and nutrition to the latest discoveries in longevity research. My goal is to lift the veil on the geroscience and longevity world and help you apply what we know to your own personal health trajectory. I care about quality science and will always be honest about what I don't know. I hope you'll find these episodes helpful!

We eat for a variety of reasons, most importantly to sustain life. Unsurprisingly, the decisions we make about what we consume can have a huge impact on our health. Equally important is how our bodies eliminate the waste created by what we ingest. After all, what goes in must come out. Are there hard and fast rules about what constitutes a healthy …let's just say it, poo? Sean Gibbons, a microbiologist at the Institute for Systems Biology in Seattle, joins The Excerpt to discuss what bowel movements, or a lack of them, reveal about our health. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Send us a textDr. Sean Gibbons, Ph.D. is Associate Professor at the Institute for Systems Biology ( ISB - https://isbscience.org/people/sean-gibbons-phd/?tab=biography ) where his lab investigates how the structure and composition of evolving ecological networks of microorganisms change across environmental gradients, with a specific focus on how ecological communities in the gut change and adapt to individual people over their lifespans (i.e. host genotype, host development and host behavior) and how these changes impact human health ( https://gibbons.isbscience.org/ ). His lab develops computational and experimental tools for investigating host-associated microbial communities to explore the interactions between ecology, evolution and ecosystem function, applying these insights to develop personalized interventions for improving human health and well-being.Dr. Gibbons received his PhD in biophysical sciences from the University of Chicago in 2015, dual-advised by Jack Gilbert and Maureen Coleman. His graduate work focused on using microbial communities as empirical models for testing ecological theory. Dr. Gibbons completed his postdoctoral training in Eric Alm's laboratory in the Department of Biological Engineering at MIT from 2015-2018. His postdoctoral work focused on developing techniques to quantify individual-specific eco-evolutionary dynamics within the human gut microbiome.Dr. Gibbons was awarded a Fulbright Graduate Fellowship to study microbiology and synthetic biology at Uppsala University in Sweden, where he earned a master's degree in 2010. His PhD work was supported by an EPA STAR Graduate Fellowship. Upon joining the ISB faculty in 2018, his startup package was supported, in part, by a Washington Research Foundation Distinguished Investigator Award.Important Episode Link - Metagenomic estimation of dietary intake from human stool - Nature Metabolism - https://www.nature.com/articles/s42255-025-01220-1#SeanGibbons #InstituteForSystemsBiology #ISB #Microbiome #Microbes #Ecology #Medicine #Dysbioses #EcologicalTherapeutics #Virome #PrecisionNutrition #GutDigitalTwin #FecalMicrobiotaTransplantation #Longevity #Aging #Healthspan  #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

THE TWO DAVIDS HEADLINE A FEB 1 PPV IN LAS VEGAS AND THE TWO CHAMPS ARE ALREADY HEATING THINGS UP IN TWO LANGUAGES! “Pitbull” Cruz's manager, Sean Gibbons, explained to BoxingScene why “Pitbull” is bypassing an automatic rematch with WBA champion Jose “Rayo” Valenzuela in favor of a likely slugfest scrap with fellow contender Angel Fierro Christian Mbilli's Canadian promoter tells BoxingScene his top-ranked WBC/WBA contender is in talks with No. 1-ranked WBO contender Diego Pacheco for a Jan. 25 super-middleweight fight that would leave the winner prominently positioned to meet Canelo Alvarez Learn more about your ad choices. Visit megaphone.fm/adchoices

Your gut microbiome consists of trillions of microbiota and is a critical health determinant, affecting your immune system, mood, energy level, and much more. As a scientific field, microbiome research is new to the scene, but the intricate relationship between our gut and our overall health is clear – and getting clearer. In April, Netflix started streaming Hack Your Health, an informative documentary about the gut microbiome, gut health, and the science of eating. In this collaborative event between Town Hall Seattle and the Institute for Systems Biology, Hack Your Health Director Anjali Nayar will sit down with gut microbiome specialist Dr. Sean Gibbons, a scientific advisor on the film, to discuss the project, interesting developments in microbiome research, and much more. Anjali Nayar is an Indian-Canadian director, former climate scientist, and tech founder. Anjali's newest film, a Netflix Original called Hack Your Health: The Secrets of Your Gut is streaming on Netflix, and her fantasy short Closer has over 5 million views and won the 2022 Prism Prize Audience Award (Canada's top music video awards). As of 2024, she is developing a slew of scripted projects and a series with the Golden State Warriors. Her prior films have been supported by Cinereach, Sundance, and Tribeca, won countless awards, jury prizes, gone theatrical, and been acquired by Netflix and Amazon. Sean Gibbons, Ph.D., is associate professor at Institute for Systems Biology. He received his PhD in biophysical sciences from the University of Chicago in 2015, winning a prestigious EPA STAR Graduate Fellowship. He completed his postdoctoral training in the Department of Biological Engineering at MIT and The Broad Institute in 2018. He joined ISB as Washington Research Foundation Distinguished Investigator and assistant professor in 2018. His research on the human microbiome has been published in top scientific journals, including Nature, Science, and Cell. Presented by Town Hall Seattle and the Institute for Systems Biology.  

In this episode, Cynthia chats with a ton of guests during Gervonta Davis vs. Frank Martin fight week live from radio row. Sean Gibbons, President of Manny Pacquiao Promotions chats with me about Manny Pacquiao coming out of retirement to possibly fight Mario Barrios! We also talk about "The People's Champ" Isaac Cruz and his upcoming fight against Ray Valenzuela which is pure violence on the 5 vs. 5 card in Los Angeles. Stephen Espinoza, former President of Showtime Sports, chats with Cynthia about the possible boxing league, His Excellency Turki Alalsheik wants to create with all the promotors involved, an update on the FREE PBC on Prime boxing shows happening in a couple months and his Tank vs. Martin prediction. Gary Antuanne Russell's first time on the show to let us know he is READY to throw down with Alberto Puello, what it's like having his older brother, former world champion, Gary Russell Jr., be his head trainer since their father recently passed away and excellent break down and Tank vs. Davis prediction. Errol Spence Jr. stops by for a quick chat about being Frank Martin's promoter for Man Down Promotions and how he is helping Martin for his first massive PPV in Viva Las Vegas. David Benavidez, The Mexican Monster stops by to chat about Canelo, moving up in weight, and predicting he is knocking out Oleksandr Gvosdyk! Jose Benavidez Sr. comes and talks with Cynthia and talks about David moving up in weight to challenge himself and tired of waiting for the Canelo fight, thoughts on Bivol's most recent performance, will David get the winner of Beterbiev vs. Bivol even if they do have a rematch, Tank vs. Martin prediction and much more! **SORRY ABOUT THE AUDIO TOWARDS THE END! THE MIC UNPLUGGED ITSELF! Learn more about your ad choices. Visit podcastchoices.com/adchoices

Welcome to "Furniture Industry News," the podcast dedicated to professionals in the home furnishings sector. Today, we explore significant trends and strategic insights from industry leaders, diving into topics ranging from market dynamics at the Interwoven fabric market to Stickley Furniture's innovative retail strategies and significant policy changes affecting the sector.Key Topics Discussed:Interwoven Fabric Market Insights:A panel discussion featuring insights from executives like Brian Burke of Crypton Mills and Sean Gibbons of STI highlighted the importance of adaptability and quality in response to changing consumer tastes and pricing pressures.Focus on the role of bold and unique designs in differentiating brands, as discussed by Ann Reynolds of Valdese Weavers, and the necessity for diversification in product offerings to meet varied consumer needs, emphasized by Suzie Roberts of Sunbrella.Stickley Furniture's Retail Strategies:Discussion on how Stickley Furniture leverages its chain of showrooms to gain consumer insights, maintaining balance in sales strategies between quick ship programs and special orders to manage uneven retail traffic, as discussed by President Edward Audi.Exploration of Stickley's strategic responses to market fluctuations, including their store enhancement plans and the move during the April 2023 market which boosted traffic significantly.Impact of the FTC's Ban on Non-Compete Agreements:Analysis of the new FTC ruling disallowing most non-compete agreements, with perspectives from industry professionals like Pat Watson of Martin Svensson and Jeff Schwall of Porter Designs on how this could affect the industry's landscape.Macy's Privatization Efforts:A deep dive into the unfolding story of Macy's privatization bid by Arkhouse Partners and Brigade Capital Management, highlighting the strategic implications and future direction of the retailer.Financial Forecasts and Strategic Adjustments:Insights into Beyond Inc.'s revised revenue forecasts and strategic market positioning, as well as Arhaus's financial performance and strategic responses to current market challenges.A look at Leon's Furniture's successful quarter, attributed to strategic product mix and operational efficiencies.Notable Quotes:"Flexibility is key in maintaining relevance in a market where trends can change with the seasons." - Brian Burke, Crypton Mills."The future belongs to those who can diversify their offerings and cater to niche markets without diluting their brand identity." - Suzie Roberts, Sunbrella."We are taking nothing for granted." - Edward Audi, Stickley Furniture.Closing Thoughts:Today's discussions underline the continuous evolution within the furniture industry, emphasizing the need for adaptability, innovation, and strategic foresight. Join us next time as we continue to provide the latest updates and insightful discussions designed to keep you informed and ahead in the furniture industry.

In the first episode of season four of Life at ADP the Podcast, Kate and Ingrid interview Sean Gibbons, the Director of Leadership Development at ADP. During the interview, Sean discusses his career journey of 23 years at ADP, his passion for developing and facilitating programs to help leaders become more effective, and ADP's implementation of a strength-based approach, explaining the positive impact it had on the company's associates and culture. To discover your strengths, please visit: https://www.tmbc.com/standout-assessment/

Today Dr. Sean Gibbons, Associate Professor at the Institute for Systems Biology, will chat with us about how the study of host-associated microbial communities can give us insights into evolution, ecology, and even human health. Host: Mark O. Martin Guest: Dr. Sean Gibbons Subscribe: Apple Podcasts, Spotify Become a patron of Matters Microbial! Links for this episode A wonderful overview of ammonites, extinct so long ago. A short biography of the late great Abigail Salyers, and another biography. My blogpost remembering Abigail and her fine mentorship of yours truly. A surprisingly solid overview of the microbiome. A fine video introducing the human microbiome. An article describing myths and misconceptions about the microbiome. The wood rat - creosote - microbiome study discussed in today's session. An introduction to the question, “What is systems biology?” The Institute for Systems Biology website. Sean Gibbons' faculty page at the Institute for Systems Biology. Sean Gibbons' laboratory webpage. Intro music is by Reber Clark Send your questions and comments to mattersmicrobial@gmail.com

Dr Sean Gibbons is an associate professor at The Institute for Systems Biology, specialising in how microbial communities in the gut evolve and adapt to individuals over their lifespans. Find out more about Sean here: https://isbscience.org/bio/sean-gibbons/ ------------------------------------------ References: https://doi.org/10.1128/mSystems.00964-21 https://www.washingtonpost.com/wellness/2023/06/13/weight-loss-calories-fiber-microbiome/ https://rdcu.be/cfslJ https://www.nytimes.com/2021/03/18/well/eat/microbiome-aging.html https://rdcu.be/cZpgI https://doi.org/10.1093/advances/nmac075 ------------------------------------------ Follow Gutology on: Youtube  Instagram  Facebook TikTok Need help with your own symptoms? Chat to one of our experts Learn more about your ad choices. Visit megaphone.fm/adchoices

My husband, Sean, is an incredible leader of our family and works tirelessly to serve his clients as a behavior analyst in the Nashville area.  Join us as we chat all about positive behavior tips, faith, parenting, and more.We also tease each other quite a bit!  Sean owns his own behavior analyst business in the Nashville area.  He will be back on the show again soon!Support the showResources at The Whole Mama: Grab your copy of 60 Tips and Tricks to Get Your Child Into Bed and Happy HERE Join the email list and grab your copy of my FREE Homeschool Like a Pro PDF HERE Join the email list and grab your copy of my FREE Whole Mama Survival Guide HERE Join our Whole Mamas Facebook Group of 500+ mamas HERE Follow me on Insta HERE Raise a "whole reader" through my online course HERE Our goal this year at The Whole Mama is to help 100 mamas start homeschooling in 2022! Will you join our movement of mamas ready to make powerful and positive changes for their children? Support the show

Sean Gibbons is the CEO of the Communications Network, a D.C.-based organization that connects, gathers, and supports leaders working in communications for good. Sean describes how he and his colleagues empower philanthropic organizations, like the Rockefeller and Ford Foundations, with strong communication tools to advance their missions. In an endless matrix of narratives and stories, Sean shares how to break through the noise with smart communications that can transform lives.

Sean Gibbons is the CEO of the Communications Network, a D.C.-based organization that connects, gathers, and supports leaders working in communications for good. Sean describes how he and his colleagues empower philanthropic organizations, like the Rockefeller and Ford Foundations, with strong communication tools to advance their missions. In an endless matrix of narratives and stories, Sean shares how to break through the noise with smart communications that can transform lives. Learn more about your ad choices. Visit podcastchoices.com/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Gut health has become such a popular topic for aging and solving many of the mysteries surrounding all kinds of diseases. We're diving into the gut microbiome to unpack this complex community of bacteria and get a better understanding of how it impacts literally every inch of our body's function and health.  Dr. Sean Gibbons is joining us for this episode to share his specialized knowledge and insights of how the gut microbiome impacts our daily activity, what we can do to better care for it, and how we can optimize our microbiomes to age better. His postdoctoral work focused on developing techniques to quantify individual-specific eco-evolutionary dynamics within the human gut microbiome.  As Dr. Gibbons simplifies these complex systems and functions for us, he reveals how much more unique we actually are thanks to our microbiomes. First, we get a GruffTalk special Masterclass on Gut Microbiome function and connections to overall health, then we answer listener questions that you submitted.  The Gut Microbiome Masterclass  Fun Fact: We have more microbes in our gut than we have human cells in our body.   Dr. Gibbons explains how we are covered in these tiny microorganisms inside and out, and how we literally have over 30 trillion bacterial cells in the first part. The second part is understanding that these bacterial cells impact our health for better or worse and the majority of these bacteria reside in our gut, which is why gut health is such a critical topic to health and better aging.  “Being an omnivore is okay as long as the vast majority of your diet is plant-based.” -Dr. Sean Gibbons  When it comes to aging and the gut microbiome, Dr. Gibbons explains the research and implications of some shocking results that were found in a study of a healthy and unhealthy older population. You won't believe how unique microbiomes correlate to the older healthy population of participants.  Lastly, this masterclass wouldn't be complete without Dr. Gibbons breaking down how microbes affect your immune system and the ways you can leverage and manipulate inflammation through your microbiome.  Listener Questions Dr. Gibbons Answers for You  Listeners of GruffTalk send in some of the best questions and we're so thankful for that. If you'd like to send any questions you want to have answered for future episodes you can send an email to grufftalkpodcast@gmail.com. Here are the topics and concerns that Dr. Gibbons gave detailed explanations for:  Things we can do throughout our lifetimes to manipulate our microbiomes  How to positively change your gut microbiome later in life  Are probiotic supplements good for you?  Which diet is best for your gut? Plant-based? Mediterranean? Carnivore?  Linking gut microbiome to disease and the impact on cancer  Should you be concerned about taking statins for gut health  Weight loss, weight gain and lifestyle choices for a healthy microbiome    Dr. Gibbons 3 Takeaways for Gut Health and Better Aging:  You're not alone. We're made of trillions of bacteria  Eat a diverse array of whole foods, mostly plant-based  Turning back the clock may not be best when it comes to your gut microbiome    “If you could do one thing, just exercise. That's probably the one single best intervention you can do for your health.” -Dr. Sean Gibbons  Connect with Dr. Gibbons  Website: https://gibbons.isbscience.org/bio/sean-gibbons-phd/   Twitter: https://twitter.com/ibbological   Connect with Barbara:   Love Your Age: The Small-Step Solution to a Better, Longer, Happier Life  Barbara Hannah Grufferman website  Instagram @Barbara Hannah Grufferman  Facebook @BarbaraHannahGruffermanAuthor  Learn more about your ad choices. Visit megaphone.fm/adchoices

Prebiotics and probiotics. Fecal microbiota transplants. Optimizing a diet personalized to you. These microbiome-themed topics are all around us in the media, but microbiome research remains a fairly nascent field of study and wasn't on many people's radars even 10 years ago. UCSD Professor Dr. Jack Gilbert and Institute for Systems Biology (ISB) Assistant Professor Dr. Sean Gibbons came together to tackle this exciting area of research. What have we learned over the past few years? What has gone well, and what could we do better? The two discussed some exciting developments on the horizon and share when they think people might see microbiome-based technologies in their daily lives. Dr. Jack A. Gilbert is a Professor of Microbial Oceanography in the Center for Marine Biotechnology and Biomedicine at Scripps Institute of Oceanography, and holds a joint appointment in the Department of Pediatrics in UCSD School of Medicine. Dr. Gilbert is also cofounder of the Earth Microbiome Project and American Gut Project, has authored more than 350 peer-reviewed publications and book chapters on microbial ecology, and is the founding Editor in Chief of mSystems journal. He has been recognized on Crain's Business Chicago's “40 Under 40 List,” listed as one of the 50 most influential scientists by Business Insider, and was named as one of the “Brilliant Ten” by Popular Scientist. He is the co-author of Dirt is Good, a popular science guide to the microbiome and children's health. Dr. Sean Gibbons is Assistant Professor at ISB. He holds a Ph.D. in biophysical sciences from the University of Chicago; his graduate work focused on using microbial communities as empirical models for testing ecological theory. Gibbons completed his postdoctoral training in Eric Alm's laboratory in the Department of Biological Engineering at MIT, where his work focused on developing techniques to quantify individual-specific eco-evolutionary dynamics within the human gut microbiome. He is particularly interested in learning how organisms in the human gut change and adapt to individual people over their lifespans, and how those changes impact health. Presented by the Institute for Systems Biology and Town Hall Seattle.

Gary takes on the real issues that the mainstream media is afraid to tackle. Tune in to find out the latest about health news, healing, politics, and the economy.  Gut microbiome implicated in healthy aging and longevity Data from over 9,000 people reveal a distinct gut microbiome signature that is associated with healthy aging and survival in the latest decades of life Institute for Systems Biology (Seattle), February 18, 2021 The gut microbiome is an integral component of the body, but its importance in the human aging process is unclear. ISB researchers and their collaborators have identified distinct signatures in the gut microbiome that are associated with either healthy or unhealthy aging trajectories, which in turn predict survival in a population of older individuals. The work is set to be published in the journal Nature Metabolism. The research team analyzed gut microbiome, phenotypic and clinical data from over 9,000 people - between the ages of 18 and 101 years old - across three independent cohorts. The team focused, in particular, on longitudinal data from a cohort of over 900 community-dwelling older individuals (78-98 years old), allowing them to track health and survival outcomes.  The data showed that gut microbiomes became increasingly unique (i.e. increasingly divergent from others) as individuals aged, starting in mid-to-late adulthood, which corresponded with a steady decline in the abundance of core bacterial genera (e.g. Bacteroides) that tend to be shared across humans. Strikingly, while microbiomes became increasingly unique to each individual in healthy aging, the metabolic functions the microbiomes were carrying out shared common traits. This gut uniqueness signature was highly correlated with several microbially-derived metabolites in blood plasma, including one - tryptophan-derived indole - that has previously been shown to extend lifespan in mice. Blood levels of another metabolite - phenylacetylglutamine - showed the strongest association with uniqueness, and prior work has shown that this metabolite is indeed highly elevated in the blood of centenarians. "This uniqueness signature can predict patient survival in the latest decades of life," said ISB Research Scientist Dr. Tomasz Wilmanski, who led the study. Healthy individuals around 80 years of age showed continued microbial drift toward a unique compositional state, but this drift was absent in less healthy individuals.  "Interestingly, this uniqueness pattern appears to start in mid-life - 40-50 years old - and is associated with a clear blood metabolomic signature, suggesting that these microbiome changes may not simply be diagnostic of healthy aging, but that they may also contribute directly to health as we age," Wilmanski said. For example, indoles are known to reduce inflammation in the gut, and chronic inflammation is thought to be a major driver in the progression of aging-related morbidities. "Prior results in microbiome-aging research appear inconsistent, with some reports showing a decline in core gut genera in centenarian populations, while others show relative stability of the microbiome up until the onset of aging-related declines in health," said microbiome specialist Dr. Sean Gibbons, co-corresponding author of the paper. "Our work, which is the first to incorporate a detailed analysis of health and survival, may resolve these inconsistencies. Specifically, we show two distinct aging trajectories: 1) a decline in core microbes and an accompanying rise in uniqueness in healthier individuals, consistent with prior results in community-dwelling centenarians, and 2) the maintenance of core microbes in less healthy individuals." This analysis highlights the fact that the adult gut microbiome continues to develop with advanced age in healthy individuals, but not in unhealthy ones, and that microbiome compositions associated with health in early-to-mid adulthood may not be compatible with health in late adulthood. "This is exciting work that we think will have major clinical implications for monitoring and modifying gut microbiome health throughout a person's life," said ISB Professor Dr. Nathan Price, co-corresponding author of the paper.      Rosmarinic acid suppresses cognitive decline in Alzheimer disease mouse model University of Tokyo (Japan), February 15, 2021   According to news originating from the University of Tokyo , research stated, “Rosmarinic acid (RA), a polyphenol found in Lamiaceae herbs, is a candidate of preventive ingredients against Alzheimer’s disease (AD) as it potently suppresses the aggregation of amyloid b (Ab); however, the effect of RA on tau phosphorylation and cognitive dysfunction remains unclear.” Financial supporters for this research include Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development; Cross-Ministerial Strategic Innovation Promotion Program. The news editors obtained a quote from the research from University of Tokyo: “The present study revealed that RA intake inhibited the pathological hallmarks of AD, including Ab and phosphorylated tau accumulation, and improved cognitive function in the 3 x Tg-AD mouse model. Additionally, RA intake suppressed hippocampal inflammation and led to the downregulation of the JNK signaling pathway that induces tau phosphorylation. Feeding with RA exerted an anti-inflammatory effect not only in the central nervous system but also in the periphery.” According to the news editors, the research concluded: “Downregulation of the JNK signaling pathway in hippocampus may be a potential mechanism underlying the inhibition of progression of pathology and cognitive deficit by RA feeding.”       Excess fatty tissue accumulated in the neck increases the chances of suffering heart problems, according to a new study University of Granada (Spain), February 15, 2021 Researchers from the University of Granada warn that an accumulation of fatty tissue in the neck (both the double chin and the deeper deposits, located between muscles and around the cervical vertebrae) is a predictor of central and overall adiposity, cardiometabolic risk, and a pro-inflammatory profile in sedentary young adults. Traditionally, the accumulation of visceral adipose tissue has been considered one of the factors most strongly related to cardiometabolic risk and chronic (low-grade) inflammation in humans. However, this well-established association has led researchers to neglect, to some degree, the study of other fatty deposits and their clinical/biological relevance. "Curiously, several studies have demonstrated that the accumulation of fat in the neck (both superficial deposits such as the double chin or jowls and the deeper deposits, located between the muscles and around the cervical vertebrae) increases in direct proportion to the weight or adiposity of the individual and that it follows specific accumulation patterns, according to gender," explains María José Arias Téllez, a researcher at the UGR and one of the main authors of this work.  In fact, a greater accumulation of fat in certain neck tissue compartments, particularly the deeper ones, is linked to a greater likelihood of cardiometabolic risk. Arias Téllez says, "However, the evidence accumulated to date has been based on experiments performed on patients with benign/malignant tumors or other chronic conditions, and it remains to be seen whether it can be generalized to relatively healthy adults." The study carried out at the UGR is part of the ACTIBATE project (Activating Brown Adipose Tissue through Exercise—seeprofith.ugr.es/actibate). The research was led by Jonatan Ruiz Ruiz and its results have been published in the International Journal of Obesity. The study shows that the accumulation of fat in the neck—measured with computed tomography scanning—as well as its distribution in different compartments, is associated with greater overall and central adiposity, greater cardiometabolic risk, and a greater inflammatory status among healthy young adults, regardless of the amount of total and visceral fat. In addition, among the most relevant findings, the researchers observed that this accumulation of fat in the neck was as powerful a factor (in terms of direction and magnitude) as the accumulation of visceral fat in the prediction of cardiometabolic risk and inflammatory status, especially in men. "Therefore, these results underline the need for further research in this new direction, to better understand the effect of fat accumulation in the upper part of the trunk (including the neck) and its clinical repercussions, especially in cardiometabolic riskand inflammation," explains Francisco Miguel Acosta Manzano, one of the main authors of the research. "We still have much work to do. We need to investigate the adipose tissue of the neck in greater depth, to understand its pathogenic role in obesity and associated comorbidities, as well as its biological importance. Furthermore, we only have scant knowledge about the morphological or molecular characteristics of the adipocytes in these deposits, and here basic studies are required. As we increase our knowledge of this deposit, we can also determine whether specific interventions (for example, physical exercise and/or restricted calorie intake) could help reduce the accumulation of fat in the neck (as well as total fat) and implement them clinically," explain Arias Téllez and Francisco Miguel Acosta Manzano, both Ph.D.s students on the Biomedicine program of the UGR's International School for Postgraduate Studies    Effects of saffron extract supplementation on mood, well-being and response to a psychosocial stressor in healthy adults Northumbria University (UK), February 16, 2021 According to news reporting originating from Newcastle upon Tyne, United Kingdom, research stated, “Anxiety, stress, and low mood are closely related and may contribute to depressive symptoms. Among non-pharmacological solutions to improve subclinical mood symptoms and resilience to stress, natural products such as saffron-identified as promising following preliminary beneficial effects in major depressive disorder-represent a relevant strategy.” Our news reporters obtained a quote from the research from Northumbria University: “This study aimed to assess the efficacy of 8 weeks’ supplementation with 30 mg standardized saffron extract on emotional well-being in healthy adults with subclinical feelings of low mood and anxiety and/or stress and evaluate the acute effect of saffron in response to a lab-based psychosocial stressor. The study adopted a double-blind, randomized, parallel groups design in which 56 healthy male and female individuals (18-54 years) received either a saffron extract or a placebo for 8 weeks. Chronic effects of saffron on subjective anxiety, stress, and depressive feelings were assessed using a questionnaire battery [including Profile of Mood State-2, (POMS)] and acute effects in response to a lab-based psychosocial stressor were measured through psychological and physiological parameters. Urinary crocetin levels were quantified. Participants who received the saffron extract reported reduced depression scores and improved social relationships at the end of the study. Urinary crocetin levels increased significantly with saffron supplementation and were correlated with change in depression scores. The typical stress-induced decrease in heart rate variability (HRV) during exposure to the stressor was attenuated following acute saffron intake.” According to the news editors, the research concluded: “Saffron extract appears to improve subclinical depressive symptoms in healthy individuals and may contribute to increased resilience against the development of stress-related psychiatric disorders. Clinical trials number: NCT03639831.”     The science of siestas: New research reveals the genetic basis for daytime napping Massachusetts General Hospital and University of Murcia (Spain), February 13, 2021   How often a person takes daytime naps, if at all, is partly regulated by their genes, according to new research led by investigators at Massachusetts General Hospital (MGH) and published in Nature Communications. In this study, the largest of its kind ever conducted, the MGH team collaborated with colleagues at the University of Murcia in Spain and several other institutions to identify dozens of gene regions that govern the tendency to take naps during the day. They also uncovered preliminary evidence linking napping habits to cardiometabolic health Napping is somewhat controversial,” says Hassan Saeed Dashti, Ph.D., RD, of the MGH Center for Genomic Medicine, co-lead author of the report with Iyas Daghlas, a medical student at Harvard Medical School (HMS). Dashti notes that some countries where daytime naps have long been part of the culture (such as Spain) now discourage the habit. Meanwhile, some companies in the United States now promote napping as a way to boost productivity. “It was important to try to disentangle the biological pathways that contribute to why we nap,” says Dashti.    Previously, co-senior author Richa Saxena, Ph.D., principal investigator at the Saxena Lab at MGH, and her colleagues used massive databases of genetic and lifestyle information to study other aspects of sleep. Notably, the team has identified genes associated with sleep duration, insomnia, and the tendency to be an early riser or “night owl.” To gain a better understanding of the genetics of napping, Saxena’s team and co-senior author Marta Garaulet, Ph.D., of the Department of Physiology at the University of Murcia, performed a genome-wide association study (GWAS), which involves rapid scanning of complete sets of DNA, or genomes, of a large number of people. The goal of a GWAS is to identify genetic variations that are associated with a specific disease or, in this case, habit.   For this study, the MGH researchers and their colleagues used data from the UK Biobank, which includes genetic information from 452,633 people. All participants were asked whether they nap during the day “never/rarely,” “sometimes” or “usually.” The GWAS identified 123 regions in the human genome that are associated with daytime napping. A subset of participants wore activity monitors called accelerometers, which provide data about daytime sedentary behavior, which can be an indicator of napping. This objective data indicated that the self-reports about napping were accurate. “That gave an extra layer of confidence that what we found is real and not an artifact,” says Dashti.   Several other features of the study bolster its results. For example, the researchers independently replicated their findings in an analysis of the genomes of 541,333 people collected by 23andMe, the consumer genetic-testing company. Also, a significant number of the genes near or at regions identified by the GWAS are already known to play a role in sleep. One example is KSR2, a gene that the MGH team and collaborators had previously found plays a role in sleep regulation.   Digging deeper into the data, the team identified at least three potential mechanisms that promote napping: Sleep propensity: Some people need more shut-eye than others. Disrupted sleep: A daytime nap can help make up for poor quality slumber the night before. Early morning awakening: People who rise early may “catch up” on sleep with a nap.   “This tells us that daytime napping is biologically driven and not just an environmental or behavioral choice,” says Dashti. Some of these subtypes were linked to cardiometabolic health concerns, such as large waist circumference and elevated blood pressure, though more research on those associations is needed. “Future work may help to develop personalized recommendations for siesta,” says Garaulet.  Furthermore, several gene variants linked to napping were already associated with signaling by a neuropeptide called orexin, which plays a role in wakefulness. “This pathway is known to be involved in rare sleep disorders like narcolepsy, but our findings show that smaller perturbations in the pathway can explain why some people nap more than others,” says Daghlas.   One or more soda a day could decrease chances of getting pregnant Boston University School of Public Health,  February 13, 2021 The amount of added sugar in the American diet has increased dramatically over the last 50 years. Much of that increase comes from higher intake of sugar-sweetened beverages, which constitute approximately one-third of the total added sugar consumption in the American diet. While consumption of these beverages has been linked to weight gain, type 2diabetes, early menstruation, and poor semen quality, few studies have directly investigated the relationship between sugary drinks and fertility. Now, a new study led by Boston University School of Public Health (BUSPH) researchers has found that the intake of one or more sugar-sweetened beverages per day—by either partner—is associated with a decreased chance of getting pregnant. The study was published in Epidemiology. "We found positive associations between intake of sugar-sweetened beverages and lower fertility, which were consistent after controlling for many other factors, including obesity, caffeine intake, alcohol, smoking, and overall diet quality," says lead author Elizabeth Hatch, professor of epidemiology. "Couples planning a pregnancy might consider limiting their consumption of these beverages, especially because they are also related to other adverse health effects." About 15 percent of couples in North America experience infertility. Identifying modifiable risk factors for infertility, including diet, could help couples conceive more quickly and reduce the psychological stress and financial hardship related to fertility treatments, which are associated with more than $5 billion in annual US healthcare costs. Through the Pregnancy Study Online (PRESTO), an ongoing web-based prospective cohort study of North American couples, the researchers surveyed 3,828 women aged 21 to 45 living in the United States or Canada and 1,045 of their male partners. Participants completed a comprehensive baseline survey on medical history, lifestyle factors, and diet, including their intake of sugar-sweetened beverages. Female participants then completed a follow-up questionnaire every two months for up to 12 months or until pregnancy occurred. Both female and male intake of sugar-sweetened beverages was associated with 20 percent reduced fecundability, the average monthly probability of conception. Females who consumed at least one soda per day had 25 percent lower fecundability; male consumption was associated with 33 percent lower fecundability. Intake of energy drinks was related to even larger reductions in fertility, although the results were based on small numbers of consumers. Little association was found between intake of fruit juices or diet sodas and fertility. "Given the high levels of sugar-sweetened beverages consumed by reproductive-aged couples in North America, these findings could have important public healthimplications," the authors concluded.

Over the last year, we've heard growing demand across the planet to change the narrative on issues from racism, poverty and capitalism - to climate change, health care and biodiversity. But what, exactly, does that mean? What are narratives? How do they influence the way we live and work? And how the heck do you change one?That's what we discuss in this episode, with Sean Gibbons, CEO of The Communications Network. His organization connects, gathers, and informs leaders working in communications for good in order to advance the missions and impact of foundations and nonprofits. Before joining the Network, Sean held senior positions at several policy think tanks in Washington and worked as an award-winning news producer for CNN. If you have any interest in social change, you need to hear what Sean has to say. Not only does he share some incredible resources with us, including the strategic toolkit Storytelling for Good (developed with the Rockefeller Foundation and Hattaway Communications), and a brand new platform for diversity, equity and inclusion – but he also tells an amazing story of how - exactly - social change leaders used stories to change the narrative on a global human rights issue - marriage. The Communications Network has some terrific resources - it's definitely worth checking out. And, if you know of any social good organizations who did amazing work to make a difference this year, Sean invites you to nominate them for the Clarence B. Jones award.

Institute for Systems Biology (ISB) is a collaborative cross-disciplinary nonprofit biomedical research organization based in Seattle. In 2020, ISB is celebrating its 20th anniversary with a four-part virtual speaker series highlighting some of the most important topics in science and health care. ISB and Town Hall proudly present microbiome researcher and professor Dr. Eric Alm. Following Dr. Alm’s talk on low-cost pandemic tracking efforts in hundreds of cities, using data collected from sewage, he’ll be joined in conversation by ISB Assistant Professor Dr. Sean Gibbons for an in-depth discussion and audience questions. Dr. Eric Alm is a professor of biological engineering at MIT. He earned his PhD from the University of Washington, and then completed postdoctoral work at UC Berkeley and Lawrence Berkeley National Lab before joining the MIT faculty. His research focuses on non-invasive monitoring of human health, environmental surveillance, sewage epidemiology, and more. Presented by Town Hall Seattle and Institute for Systems Biology.  To make a donation or become a Town Hall Seattle member click here or text TOWN HALL to 44321. 

Sean is the 2020 SRO GT4 SprintX Champion. Sean gives great insight into his career and how he is successful with obtaining sponsorships. I always enjoying talking with Sean. He has a great passion for the sport and the industry. Dont forget to visit our partners www.intrinsicproducts.com and use the cod uber to the pits at checkout for 10% off. Please to announce our new partner The Racers Safety Source. www.theracerssafetysource.com

There are no excuses not to make it to ComNet this year – it’s free and it’s virtual. So you don’t have to leave the house and you can attend in your pajamas. Eric speaks with the Communications Network’s CEO Sean Gibbons about all the amazing keynotes, breakouts, and the annual Day of Service, which will give participants the opportunity to support a fair count of the US Census. And if you haven’t signed up yet, it’s not too late – go to comnetworkvirtual.org until September 21. Did we mention that it’s free?

There are no excuses not to make it to ComNet this year – it’s free and it’s virtual. So you don’t have to leave the house and you can attend in your pajamas. Eric speaks with the Communications Network’s CEO Sean Gibbons about all the amazing keynotes, breakouts, and the annual Day of Service, which will give participants the opportunity to support a fair count of the US Census. And if you haven’t signed up yet, it’s not too late – go to comnetworkvirtual.org until September 21. Did we mention that it’s free?

Sean Gibbons, PhD, is a distinguished investigator at the Washington Research Foundation and assistant professor at the Institute for Systems Biology. He joins the show today to discuss the work being done in his lab. Tune in to learn the following: How species diversity in the human gut microbiome may lend itself to health and disease states of the host, patterns seen at the high and low ends of diversity, and how to qualify the meaning of “diversity” What findings Gibbons' work has shown, including the importance and implications of the intimate connection between the metabolites produced in the gut and the metabolites circulating in the bloodstream What patterns and characteristics are found in the microbiome during aging, and how analysis in this regard could provide predictive information about mortality Gibbons has a background and long-standing interest in the ecology, microbiology, and evolutionary biology of microbial communities, and for the past several years, he's been studying the human body through this lens. His lab is focused on trying to understand the variation in the ecology and evolutionary dynamics of the microbial communities that drive changes in the molecular phenotypes of host organisms. Gibbons and his team are accomplishing this by looking at the microbiome of healthy and sick individuals, as well as detailed molecular phenotypic data on the metabolome, proteome, human genome sequence, and dietary and lifestyle measurements. The ultimate goal is to understand what amount of variation in the ecology of microbial communities in the human body is coherent with variation in disease states. By doing this, the hope is to determine where the microbiome is involved in the etiology of disease. Gibbons discusses a number of fascinating topics, including the significance of low versus high species diversity in the gut microbiome, how bacteria in the gut compete and interact with one another, patterns found in the relationship between ageing and the gut microbiome, how information about the structure of someone's microbiome can be obtained by analyzing the metabolites in a sample of their blood, why a reliance on mouse models in the study of the human microbiome is not ideal, how Gibbons' team is trying to develop methods that will bring research findings closer to showing causality as opposed to just correlation, the importance of longitudinal data and interventional studies for moving the microbiome into clinical medicine, and so much more. Check out https://gibbons.isbscience.org/ to learn more.

Sean Gibbons is CEO of the Communications Network, a professional network of foundation and nonprofit leaders that improve lives through smart communication.  Sean is also living proof that in today’s dynamic economy, it is becoming more and more common for professionals to change jobs almost a dozen times between the ages of 18-48!  During his successful career, Sean has worked in journalism as well as in communication strategy in think tanks, and nonprofits. The post 188: How to Break Into Communications in the Social Good Space w/ Sean Gibbons, The Communications Network [Espresso Shots] appeared first on Time4Coffee.

Sean Gibbons is CEO of the Communications Network, a professional network of foundation and nonprofit leaders that improve lives through smart communication.  Sean is also living proof that in today’s dynamic economy, it is becoming more and more common for professionals to change jobs almost a dozen times between the ages of 18-48! During his career,  Sean has worked in journalism, communication strategy in think tanks, and nonprofits. Before he worked in communications, Sean built a career in journalism as an award-winning producer at CNN. He served as the Washington producer for shows like American Morning, News Night with Aaron Brown, and Anderson Cooper 360.   The post 140: What It’s Like to Build a Career in Communications w/ Sean Gibbons, The Communications Network [Main T4C episode] appeared first on Time4Coffee.

Every Thursday night at 6:00pm PST, LIITR host and founder Dave (@LIITRBOXING) Duenez and co-host Gabriel Montoya talk all the latest boxing news on Leave it in the RinG. Dave and Gabriel give a fresh and unfiltered take on the world of boxing with fan interactive debates, breaking news, and in-depth interviews with the top names in the sport. Tonight, Dave and Gabriel review and preview the weekend's boxing action, discuss the fallout from Eddie Hearn's DAZN deal and they welcome guest Sean Gibbon to the show. And the LIITR crew takes fight fans' calls from our hotline 347-215-7598. Support independent #boxing media like @LIITRBoxing by pledging it on @Patreon: https://www.patreon.com/LIITRBOXING

Episode 20, Sean Gibbons, Communications Network by Hattaway Communciations

ComNet16: The Communications Network CEO Sean Gibbons In Conversation With Professor Aaron Belkin by The Communications Network

This week we speak with Sean Gibbons, CEO of the The Communications Network, an organization that connects leaders seeking to elevate and advance communications for good. As 2017 comes into focus, foundations and nonprofits are trying to find their way in a crowded communications landscape. We discuss the relationship between good communications and good strategy, ways to create a communicating organization, and the importance of research and data that gets beyond demographics. We look forward to any feedback. You can hit us up anytime at podcast@hattaway.com. You can check for updates on our podcast on our website, hattaway.com.

Sean Gibbons explains why organizations that do communications well are smarter, stronger, and vastly more effective than those that don't.

Sean Gibbons explains why organizations that do communications well are smarter, stronger, and vastly more effective than those that don't.

Sean Gibbons explains why organizations that do communications well are smarter, stronger, and vastly more effective than those that don’t. The post Ep 13: Extraordinary Nonprofit Communications – with guest Sean Gibbons appeared first on Joan Garry Nonprofit Leadership.

Josh and Jimmy report in on just exactly how exhausted they are from GP Vegas with fun interviews with some friends at the event - Jason Alt & Corbin Hosler from Brainstorm Brewery, Sean Gibbons from Wizards of the Coast, Magic's greatest cosplayer Christine Sprankle, and flavor expert AEMarling. Learn more about your ad choices. Visit megaphone.fm/adchoices