Podcast appearances and mentions of stephanie faubion

Send us a textIn this episode of the Hotflash inc Podcast, host Ann Marie McQueen sits down with fellow journalist and midlife advocate, Tamsen Fadal. A veteran Emmy Award-winning news anchor, Tamsen has transformed her career into a powerful force for women in midlife. From creating the groundbreaking PBS documentary The M Factor: Shredding the Silence on Menopause to her upcoming book How To Menopause (out March 2025), Tamsen is on a mission to change the conversation around menopause, confidence and aging.Connect with Tamsen Fadal:Website: www.tamsenfadal.comIG: @tamsenfadalTikTok: @tamsenfadalYouTube: Tamsen FadalThe M Factor Documentary: Watch hereThanks to our sponsor Timeline Nutrition Mitopure supports cellular energy and longevity—now available with a 10% discount! Visit timeline.com/HOTFLASH and use the code HOTFLASH to claim your offer!From The M Factor team: This partial statement is in response to Hotflash inc's request for comment in light of recent reports and fact-checking of the film by ob-gyn Dr Jen Gunter and published on her platform, The Vagenda. The M Factor: Shredding the Silence on Menopause” documentary earned continuing medical education (CME) Accreditation. On October 17, 2024 the Federation of State Medical Boards (FSMB) hosted a 90-minute live webinar offering continuing medical education (CME) credit for healthcare providers. The event featured the documentary “The (M) Factor: Shredding the Silence on Menopause,” which was followed by a moderated discussion with menopause experts Dr. Stephanie Faubion, Mayo Clinic and The Menopause Society and Dr. Wen Shen, Johns Hopkins Medical,  moderated by FSMB board members and one of the film producers. Due to the limited capacity FSMB had for live registrations, CME credit was extended to those on the waitlist who accessed the recorded webinar online. After the live event, FSMB provided access to the recorded webinar for a limited period, and that window closed as scheduled. Accreditation remains intact for all participants, whether live or virtual. The FSMB CME webinar and accreditation concluded on November 21, 2024. We stand by our film and the medical doctors who shared their expertise with us. We recognize that others have different viewpoints.  We respect them all and we look forward to working together to help women live longer healthier lives.  Join the Hotflash inc perimenoposse: Web: hotflashinc.comNewsletter: Hotflash inc. on SubstackTikTok: @hotflashincInstagram: @hotflashincX: @hotflashinc Episode website: Hotflashinc Listen on: Apple Podcasts | Spotify | Google Podcasts | YouTube | Substack See hotflashinc.com/privacy-policy for privacy information

Dr. Stephanie Faubion, MD, MBA from the Women's Health Clinic at Mayo Clinic joins AAOHN to discuss menopause for women in the workplace. Menopause is a universal experience impacting most women from physical symptoms to cognitive or mental health issues affecting both working life and personal life.  While menopause typically happens at the mean age of 52, nearly 8% of women under the age of 45 will enter menopause with a long working life yet ahead of them. Join this conversation to learn so much more from our expert, and increase your ability to have those culturally competent and sensitive conversations.

August 2, 2023 - Dr Stephanie Faubion

Welcome to the Feel Good Podcast with Kimberly Snyder. My goal is to help you develop a holistic lifestyle based on Four Cornerstone philosophy - food, body, emotional wellbeing and spiritual growth.  This holistic approach will help you feel good, which I define as being connected to your most authentic, highest self. And this is the place from which your energy, confidence, creativity, true power and true beauty will start to explode. Every week we provide you with interviews from top experts in their field or a solocast from yours truly to support you in living your most beautiful, healthy and joyful life.  I'm your host, Kimberly Snyder. Founder of Solluna, a multiple time New York Times bestselling author, spiritual and meditation teacher, nutritionist, and wellness expert.

**Disclaimer: This episode may be best listened to by listeners over the age of 13 as women's reproductive and menopausal health is discussed. Today on the podcast, we have renowned women's health expert Dr. Stephanie Faubion. We had the opportunity to chat about all things regarding menopause, including hormone therapy, non-hormonal therapy, timeline, and Dr. Faubion's newest book, The New Rules of Menopause.About the Guest:Stephanie S. Faubion, M.D., M.B.A., is the Penny and Bill George Director of Mayo Clinic's Center for Women's Health and is chair of the Department of Medicine at Mayo Clinic in Jacksonville, Florida. Dr. Faubion has been a physician in the Women's Health Clinic at Mayo Clinic for over 18 years. She also serves as medical director for The Menopause Society. She has a broad interest in women's health and has evaluated and treated women with menopausal, hormonal, and sexual health concerns. Her research encompasses sex and gender-based differences in disease, menopause, hormone therapy, healthy aging, and sexual health and dysfunction in women — addressing questions directly from the clinical dilemmas faced daily in medical practice. A leader in women's health, Dr. Faubion frequently lends her expertise to the New York Times, Washington Post, Wall Street Journal, CNN, NBC News, and other national media.https://www.amazon.com/New-Rules-Menopause-Clinic-perimenopause/dp/1945564113/ref=sr_1_1?gclid=Cj0KCQjw9MCnBhCYARIsAB1WQVUlLgyRyQI8F9gdzq02OqDOSkuTE0zCG1zQf3c8DzW6xN8LiUi5lFIaAnvsEALw_wcB&hvadid=662949874486&hvdev=c&hvlocphy=9013168&hvnetw=g&hvqmt=e&hvrand=18347884620562523662&hvtargid=kwd-2111071209560&hydadcr=22566_13493360&keywords=the+new+rules+of+menopause&qid=1693495624&sr=8-1https://www.mayo.edu/research/faculty/faubion-stephanie-s-m-d-m-b-a/bio-20199366https://twitter.com/i/flow/login?redirect_after_login=%2Fstephfaubionmdhttps://www.linkedin.com/in/stephanie-faubion-254307103www.menopause.orgwww.mayoclinic.orgAbout the Host: Following the crumbs in the chaos is a full-time job as a Productivity Coach. As a busy mom of three and the founder of Chaos N' Cookies, keeping moms from crumbling is my main objective. After gaining 10+ years of experience as a Director of Marketing helping build multiple 6 & 7-figure businesses for other women I've created the Chaos Control System to equip moms to overcome their own objections so they can live the life they want to live and start that business they have always wanted. The Family Playbook, or standard operating procedure, is the tool every mama needs to save time and stress-less when chaos ensues at home. For new biz owners, I also help simplify systems on social media and other business platforms to automate processes to get their business up and running quickly and efficiently with how-tos and hands-on...

My guest is a women's health expert from the Mayo Clinic, and author of the new book, “The New Rules of Menopause.” We enjoy the difference between menopause and perimenopause, the role of hormone therapy, myths about these topics, and much more.  

The conversation around menopause is moving at lightspeed these days, with a wave of misinformation following quickly in its wake. So this week we sat down with the medical director of The Menopause Society (formerly the North American Menopause Society), Dr. Stephanie Faubion, author of The New Rules of Menopause to catch up on where we are with our understanding of menopause, menopause therapies, hormone testing, and much more.Stephanie S. Faubion, M.D., M.B.A., is the Penny and Bill George Director of Mayo Clinic's Center for Women's Health and is chair of the Department of Medicine at Mayo Clinic in Jacksonville, Florida. Dr. Faubion has practiced as a physician in the Women's Health Clinic at Mayo Clinic for over 18 years. She also serves as medical director for The Menopause Society. She has a broad interest in women's health and has evaluated and treated women with menopausal, hormonal, and sexual health concerns. Her research encompasses sex and gender-based differences in disease, menopause, hormone therapy, healthy aging, and sexual health and dysfunction in women — addressing questions that come directly from the clinical dilemmas faced every day in medical practice. A leader in women's health, Dr. Faubion, frequently lends her expertise to the New York Times, Washington Post, Wall Street Journal, CNN, NBC News, and other national media. Follow Us on Instagram:Feisty Menopause: @feistymenopause Feisty Media: @feisty_media Selene: @fitchick3 Subscribe to the weekly Feisty Menopause blog: https://www.feistymenopause.com/feistyinbox Hit Play Not Pause Facebook Group: https://www.facebook.com/groups/807943973376099 Join Level Up - Our Community for Active Women Navigating the Menopause TransitionJoin: https://www.feistymenopause.com/monthly-membership-1 Leave your questions for Selene:https://www.speakpipe.com/hitplay Get the Free Feisty Women's Guide to Lifting Heavy Sh*t:https://www.feistymenopause.com/liftheavy Support our Partners:The Amino Co: Shop Feisty's Favorite 100% Science-Backed Amino Acid Supplements. Enter code HITPLAY at Aminoco.com/HITPLAY to Save 30% + receive a FREE gift for new purchasers! Previnex: Get 15% off your first order with code HITPLAY at https://www.previnex.com/ Cool-Jams: Use the code HITPLAY for 15% off all products at https://www.cool-jams.com/?utm_medium=podcast&utm_source=spotify&utm_campaign=hit-play-not-pause_20230802 Nutrisense: Go to nutrisense.io/hitplay and use the code HITPLAY30 for $30 off any subscription to the CGM program

It's no secret that there is a connection between menopause and hot flashes, but there are many other symptoms that are consequences of a lack of estrogen beyond night sweats, vaginal dryness, and bone loss. And joint pain is definitely on that list. So, what is the impact of menopause on arthritis and joint pain? Is estrogen therapy the answer?  In this episode I am joined by Dr. Stephanie Faubion, the Director of Mayo Clinic's Center for Women's Health, chair of the Department of Medicine at Mayo Clinic in Jacksonville, Florida, the medical director for The Menopause Society, and the author of The New Rules of Menopause: A Mayo Clinic guide to perimenopause and beyond  We discuss: The relationship between JOINT ACHES and ESTROGEN If it is the CARTILEDGE, BONE, or BOTH that appears to be impacted by the loss of estrogen  Why so many women are diagnosed with FIBROMYALGIA at the time of menopause Why SLEEP APNEA also increases in Menopause and contributes to fatigue If HORMONE THERAPY should be prescribed to help achy joints and arthritis The increased prevalence of CARPAL TUNNEL SYNDROME and FROZEN SHOULDER If joint pain is an indication of OSTEOPOROSIS If most DOCTORS are aware of the relationship between joint aches and estrogen When joint aches are NOT RELATED to MENOPAUSE The impact of estrogen therapy and JOINT REPLACEMENT OTHER FACTORS that contribute to achy joints post-menopause and what can help The importance of ERGONOMICS and joint pain Why I do SQUATS while I brush my teeth Dr. Faubion's New Book: The New Rules of Menopause: A Mayo Clinic guide to perimenopause and beyond  To find a Menopause Society  certified menopause practitioner Other Related Episodes: Episode 22:  Dreaming of Sleep with Dr. Faubion  Episode 46 Finding a Menopause Clinician Who Will Listen  Episode 61 Boning Up on Bones: Part 2 with Dr. Kristi Tough DeSapri (Prevention and Treatment)  Episode 67- How Long Can You Safely Take Hormone Therapy? Lauren Streicher, MD is a clinical professor of obstetrics and gynecology at Northwestern University's Feinberg School of Medicine, and the founding medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause. She is a certified menopause practitioner of the North American Menopause Society.                           Sign up to receive DR. STREICHER'S FREE NEWSLETTER Dr. Streicher is the medical correspondent for Chicago's top-rated news program, the WGN Morning News, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr. Radio, Nightline, Fox and Friends, The Steve Harvey Show, CBS This Morning, ABC News Now, NBCNightlyNews,20/20, and World News Tonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine, and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine.  Subscribe and Follow Dr. Streicher on  DrStreicher.com Instagram @DrStreich Twitter @DrStreicher Facebook  @DrStreicher YouTube  DrStreicherTV Books by Lauren Streicher, MD  Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Sex Rx- Hormones, Health, and Your Best Sex Ever The Essential Guide to Hysterectomy

Are you a boomer who is concerned about maintaining your youth and vitality for years to come? If so… you will want to be sure to take a listen to what Dr. Stephanie Faubion has to say. Dr. Faubion is the Director of Mayo Clinic's Center for Women's Health and is chair of the Department of Medicine at the Mayo Clinic in Jacksonville, Florida. She has practiced at the Mayo Clinic's Women's Health Clinic at for over 18 years and also serves as the medical director for The North American Menopause Society. So, we are extremely fortunate to have such an expert share all about her just released book entitled, The New Rules of Menopause: A Mayo Clinic Guide to Perimenopause and Beyond. The book is filled with tips, strategies and more for successfully navigating later life while optimizing both your physical and mental health. If you want to make the most of your own golden years, you'll want to make sure you catch this show!

August 2, 2023 - Dr Stephanie Faubion

This triple-digit summer heat has only made it that much harder for those of us who suffer from hot flashes!A hot flash– for those lucky enough not to know– is a sudden warm feeling in your face, neck and chest. The skin gets flushed and you start to sweat. Some people also experience anxiety among other symptoms."These symptoms are manageable and women don't have to suffer. We know that the majority of women out there who are having hot flashes aren't getting treated for them," said Dr. Stephanie Faubion, director of Mayo Clinic's Women's Health. Her expertise on hot flashes is in relation to menopause–the time marking the end of a person's menstrual cycles.We discuss treatment options, the latest research and more!Support the show

09 May 2023: Julie Mallon is explaining how a lack of sleep can affect childrenCoach Rob Graham is turning kids into athletesA record breaking yoga event is taking place in DubaiShould new policies be in place for women in the workplace?Defense Mechanism Vs Coping mechanisms, what's the difference?See omnystudio.com/listener for privacy information.

The transition into menopause is an inevitable part of life. For many, it's accompanied by a range of symptoms including hot flashes, insomnia and weight gain. Ali Rogin speaks with Dr. Stephanie Faubion, director of the Mayo Clinic's Center for Women's Health and medical director of the North American Menopause Society, about why menopause continues to be understudied and undertreated. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

The transition into menopause is an inevitable part of life. For many, it's accompanied by a range of symptoms including hot flashes, insomnia and weight gain. Ali Rogin speaks with Dr. Stephanie Faubion, director of the Mayo Clinic's Center for Women's Health and medical director of the North American Menopause Society, about why menopause continues to be understudied and undertreated. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders

With so much hype surrounding menopause hormone therapy today, it's very hard to know what or who to believe. There is a big push to portray HRT not only as helpful for menopause symptoms, but also as a preventative for cardiovascular disease. But does this bear out in the research we have so far? That was the question of the latest literature review published  American Heart Association' journal Circulation this past Valentine's Day – Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long? – that looked at 96 papers, articles and studies. The authors included gynecologists, women's health internists, endocrinologists, as well as Stephanie Faubion, medical director for the North American Menopause Society, all members of the American College of Cardiology Cardiovascular Disease in Women Committee. Kathryn Lindley, an MD and clinical investigator in the Division of Cardiovascular Medicine at Vanderbilt University Medical Center and one of the authors of the paper is my guest on the podcast this week to break down these findings.Highlights: • why cardiologists have shied away from the topic of HRT• why HRT isn't recommended for prevention of cardiovascular disease (even if it seems like it should be)• the case for HRT to help symptoms• calculating the of using HRT for symptoms ("it's not zero but...")• why other health conditions matter• when it comes to vaginal estrogen...• respecting the HRT "the window of opportunity" • so, what can you do to prevent heart disease and stroke?• the case for assessing reproductive risk factors (and what you need to tell your doctors about your previous reproductive life – even if she doesn't ask)• the importance of taking in medical news in the media with "skepticism"• the case for keeping top of your health during perimenopause and taking action early for your future healthJoin the Hotflash Inc perimenoposse: Web: hotflashinc.comTikTok: @hotflashincInstagram: @hotflashincTwitter: @hotflashinc Episode website: Hotflashinc See hotflashinc.com/privacy-policy for privacy information

When New York Times Magazine staff writer Susan Dominus began reporting her cover story on menopause, she was surprised by the number of women she met who had resigned themselves to a life of hot flashes, poor sleep, brain fog and depression, all of which are common symptoms of menopause. There was a near universal acceptance that this was their new reality. But in fact, there are medically accepted therapies, like hormone treatment, to address these symptoms. Yet few women seem to be offered this relief. Why is menopause, a normal biological condition that over a million women in the U.S. will enter each year, so misunderstood? And are women conditioned to tolerate suffering such that they don't seek help for menopausal symptoms? We'll talk to Dominus and experts about menopause and hear from you: What have you been told about menopause that you have come to question? Guests: Susan Dominus, staff writer, New York Times Magazine - Dominus wrote the recent New York Times Magazine article "Women Have Been Misled About Menopause" Dr. Stephanie Faubion, medical director, North American Menopause Society; director of the Center for Women's Health, Mayo Clinic Omisade Burney-Scott, creator of the "Black Girls Guide to Surviving Menopause"

The good news: we are finally talking about menopause! The not so good news: we still have a long way to go, especially in the realm of research, says this week's guest Dr. Stephanie Faubion, who is on the tip of the spear leading the way forward as the Medical Director of The North American Menopause Society (NAMS). When it comes to dealing with menopause openly in our culture, especially in the workplace, Dr. Faubion believes we are where we were with pregnancy 30 years ago. And she has some ideas on how we can all help accelerate progress and bring our doctors and culture up to speed. Along with her role as Medical Director of NAMS, Dr. Faubion is Professor and Chair of the Department of Medicine at Mayo Clinic in Jacksonville, Florida, and Director of the Mayo Clinic Center for Women's Health. Her expertise is in women's health, clinical research, education, and clinical practice. You can learn more about her and her work at mayo.edu.**Support the Podcast** InsideTracker: Get 20% off at insidetracker.com/feistyPrevinex: Get 15% off your first order with code HITPLAY at https://www.previnex.com/ Bonafide: Get 20% off your first purchase when you subscribe to any product with code HITPLAY at hellobonafide.com/hitplayThis podcast uses the following third-party services for analysis: Podsights - https://podsights.com/privacyChartable - https://chartable.com/privacy

This is a special episode of Hot Flashes & Cool Topics because we have two amazing women who are on the forefront of modern menopause technology and research. Dr. Stephanie Faubion is Director for Mayo Clinic's Center for Women's Health and medical director for The North American Menopause Society.  She is one of the most educated and experienced menopause clinicians in the U.S.  We also have Ann Garnier who has spent decades in the women's health community, CEO and founder of Lisa Health and co-founder of Midday Health. We spoke with both directly after the 2022 North American Menopause Society Forum where the latest research for menopause is shared.  You will learn about the updated statement on hormonal therapy, nonhormonal alternatives and more. We also discuss Mayo's collaboration with Lisa's Health for the new app Midday Health.  This app is a science-backed and evidence-based app that uses data to illuminate what is happening physically and emotionally during menopause.  It also uses AI and digital alternative like your fitbit to track symptoms. Listen and subscribe to Hot Flashes & Cool Topics on any podcast platform and find links in our Show Notes on our website. www.hotflashescooltopics.com Want to Leave a Review for Hot Flashes and Cool Topics? Here's How: For Apple Podcasts on an iPhone or iOS device: Open the Apple Podcast App on your device. Click on the “search” icon Type into the search bar “Hot Flashes and Cool Topics” and click on the show Towards the bottom, look for “Ratings and Reviews” Click on “Write a Review” and leave us your thoughts and comments! For Apple Podcasts on a computer: On the Apple Podcasts website, go to the search bar and type “Hot Flashes and Cool Topics” After clicking on the show, find the “Listen on Apple Podcasts” button and click on it The “Hot Flashes and Cool Topics” podcast should open on the Apple Podcasts application Keep scrolling on the page until you see “Ratings and Reviews” Click on “See All” If you want to give us a five-star rating, hover over the empty stars! If you want to leave your thoughts and comments, click on “Write a Review”!  

Video: No, this intensely aggressive AI isn't fake (details in comment), w Elon Musk. (13:44) PEOPLE FOR PEOPLE RADIO - DR ANA MIHALCEA MD PhD AND GUEST SASHA LATYPOVA 11TH SEPTEMBER 2022  Neil Oliver - '...digital enslavement is coming...'  New Rule: A Unified Theory of Wokeness | Real Time with Bill Maher (HBO)   Omega-3 fatty acid stops known trigger of lupus Michigan State University, September 29, 2022    A team of Michigan State University researchers has found that consuming an omega-3 fatty acid called DHA, or docosahexaenoic acid, can stop a known trigger of lupus and potentially other autoimmune disorders.   "What we discovered was when lupus was triggered by crystalline silica, a toxic mineral also known as quartz that's linked to human autoimmunity, DHA blocked the activation of the disease," said Melissa Bates, one of the study's lead authors in MSU's Department of Food Science and Human Nutrition and the Institute of Integrative Toxicology.   The preclinical study looked at the effect of DHA on lupus lesions in the lungs and kidneys of female mice that were already genetically predisposed to the disease. Their results were overwhelmingly positive.   "Ninety-six percent of the lung lesions were stopped with DHA after being triggered by the silica," said Jack Harkema, another study author and pulmonary pathologist. "I've never seen such a dramatic protective response in the lung before."   Lupus is considered a genetic disease and is triggered not only by inhaling crystalline silica toxicants, but also by other environmental factors such as sun exposure. Quartz is the most common, and most dangerous, form of crystalline silica and is often found in the agriculture, construction and mining industries where workers can breathe in the mineral dust. Lupus is the body's immune system attacking itself and it can damage any part of the body including skin, joints and organs.   Although it's still unknown exactly why DHA is able to prevent the onset of lupus, the researchers said this study provides scientists with a better model for looking at just how much DHA is needed to ward off the environmental trigger of the disease.   According to Harkema, the DHA could be changing the way cells, also known as macrophages, react to the silica in the lungs and somehow alter the immune system's response.   "What we do know is this study is a clear indication that eating DHA can prevent this one type of environmental triggering of lupus," Pestka said. "It can suppress many of the disease's signaling pathways, which current drugs on the market now try to target and treat."     Study offers real-world evidence of vitamin D's protective effects German Cancer Research Center, October 12 2022.  A study reported in the Journal of Internal Medicine provides “real-world” evidence of the benefits of vitamin D supplementation.  “Given the increasing importance of real-world evidence in determining the drug effectiveness outside of the strictly defined and controlled situations of randomized controlled trials, it is of great interest how the efficacy data of vitamin D3 supplementation obtained from well-defined and well-controlled clinical trial populations translate into effectiveness in real-world practice,” the authors remarked. “The primary objective of this study was to investigate whether the intake of vitamin D supplements (in the form of a vitamin D preparation or as part of a multivitamin product) is associated with reduced all-cause and cause-specific mortality including cancer mortality, cardiovascular disease mortality and respiratory disease mortality in the large UK Biobank, a nationwide, population-based cohort from the United Kingdom.” The researchers analyzed information from 445,601 UK Biobank participants. Regular vitamin D supplement use was reported by 4.3% of the participants and multivitamin use was reported by 20.4%.  Vitamin D and multivitamin supplement users had higher median 25-hydroxyvitamin D levels than nonusers. Multivitamin users experienced a 74% reduction in the risk of vitamin D deficiency and users of over-the-counter vitamin D supplements had an 84% lower risk. During the 11.8-year median follow-up, individuals who used multivitamins had a 5% lower risk of mortality and those who used vitamin D had a 10% lower risk compared to nonusers. Regular vitamin D use was associated with 11% lower risk of dying from cancer and a 29% lower risk of mortality from respiratory disease.  “This large study suggests that in the real world, the efficacy of vitamin D supplements in reducing mortality may be at least as good as observed in randomized clinical trials,” the authors concluded.   What you eat could contribute to your menstrual cramps North American Menopause Society, October 12, 2022 Despite the fact that menstrual pain (dysmenorrhea) is the leading cause of school absences for adolescent girls, few girls seek treatment. An analysis of relevant studies suggests that diet may be a key contributor, specifically diets high in meat, oil, sugar, salt, and coffee, which have been shown to cause inflammation. Results will be presented during The North American Menopause Society (NAMS) Annual Meeting in Atlanta. Roughly 90% of adolescent girls experience menstrual pain. Most use over-the-counter medicine to manage the pain but with limited positive results. Evidence has highlighted that diets high in omega-3 fatty acids and low in processed foods, oil, and sugar reduce inflammation, a key contributor to menstrual pain. This analysis was designed to study the effect of diet on menstrual pain and identify which foods contribute to it and which can reduce it. Research was conducted through a literature review that found multiple studies that examined dietary patterns that resulted in menstrual pain. In general terms, these studies found that diets high in omega-6 fatty acids promote inflammation and foods high in omega-3 fatty acids reduce it. The muscles in the uterus contract because of prostaglandins, which are active in inflammatory responses. When measuring the Dietary Inflammatory Index, it was found that those on a vegan diet (that excluded animal fat) had the lowest rates of inflammation. “Researching the effects of diet on menstrual pain started as a search to remedy the pain I personally experienced; I wanted to understand the science behind the association. Learning about different foods that increase and decrease inflammation, which subsequently increase or reduce menstrual pain, revealed that diet is one of the many contributors to health outcomes that is often overlooked. I am hopeful that this research can help those who menstruate reduce the pain they experience and shed light on the importance of holistic treatment options,” says Serah Sannoh, lead author of the poster presentation from Rutgers University. “Since menstrual pain is a leading cause of school absenteeism for adolescent girls, it's important to explore options that can minimize the pain. Something like diet modification could be a relatively simple solution that could provide substantial relief for them,” said Dr. Stephanie Faubion, NAMS medical director.   Free radicals blamed for toxic buildup in Alzheimer's brains Rutgers University, October 10, 2022.  A study reported in Cell Death & Disease revealed a previously unknown mechanism that may contribute to traumatic brain injury and Alzheimer's disease. While a buildup of the protein amyloid-beta has been hypothesized to be the major driver of Alzheimer's disease, the study suggests that another protein, after undergoing oxidation by free radicals, could be a causative factor. "Indeed, scientists have known for a long time that during aging or in neurodegenerative disease cells produce free radicals," explained lead researcher Federico Sesti, who is a professor of neuroscience and cell biology at Rutgers Robert Wood Johnson Medical School. "Free radicals are toxic molecules that can cause a reaction that results in lost electrons in important cellular components, including the channels." Dr Sesti and colleagues determined that oxidation of a potassium channel known as KCNB1 results in a toxic buildup of this protein, leading to increased amyloid-beta production and damage to brain function. "The discovery of KCNB1's oxidation/build-up was found through observation of both mouse and human brains, which is significant as most scientific studies do not usually go beyond observing animals," Dr Sesti reported. "Further, KCBB1 channels may not only contribute to Alzheimer's but also to other conditions of stress as it was found in a recent study that they are formed following brain trauma."     How much radioactivity is in infant formula?  University of Malaya & University of Surrey (UK), October 10, 2022   Based on measurements of radioactivity in samples of infant formula manufactured and sold around the world, researchers estimate that infants 1 year of age or younger who consume these formulas would ingest a significantly higher radioactivity dose than reported levels, but lower than internationally recommended limits. The researchers report the radioactivity levels for each brand of formula in an article published in Environmental Engineering Science, a peer-reviewed journal.   Onoshohwo Bemigho Uwatse and coauthors, University of Malaya (Kuala Lumpur, Malaysia), University of Surrey (U.K.), and King Saud University (Riyadh, Saudi Arabia), determined the levels of radioactive radium, potassium, radium, and thorium in 14 brands of powdered infant milk prepared and sold in various regions around the world. Levels of radioactivity in the formula may vary depending on several factors including radioactivity in the soil, grass, or hay from which the cows were fed, in other raw materials used in processing the formula, or due to processing conditions.   "This paper focuses on a topic that has not drawn significant attention but, nonetheless, has important health implications," says Domenico Grasso, PhD, Editor-in-Chief of Environmental Engineering Science and Provost, University of Delaware.   Using more social media increases depression risk for all personality types, study says University of Arkansas, October 11, 2022 Public policy and education researchers found that higher social media exposure may contribute to depression, regardless of personality traits. In their recent study, high neuroticism was associated with an increased risk of developing depression within six months. On the other hand, low agreeableness was associated with a greater depression risk within that period. The study's authors suggest that interventions should encourage reduced social media use for all personality types, especially high neuroticism, and low agreeableness. Experts have found evidence that suggests that increased social media use (SMU) may increase the risk of developing depression for certain personality characteristics, as the study showed that people low in conscientiousness with high SMU were more likely to perceive social isolation. A new study led by University of Arkansas researchers further explores how personality traits may influence the development of SMU-related depression. The findings appear in the Journal of Affective Disorders Reports.  Merrill and co-authors used data collected over six months by researchers, using a national sample of 978 people aged 18–30.  Merrill explained that her team used the Patient Health Questionnaire to assess depression at baseline and follow-up. The participants in this study reported how much time they spent on 10 leading social media platforms. The researchers assessed personality traits. They examined data for associations between personality characteristics (neuroticism, agreeableness, openness, conscientiousness, and extraversion), social media use, and the development of depression over 6 months. The team found that participants with high agreeableness were 49% less likely to develop depression than those with low agreeableness. However, individuals with high neuroticism were more than twice as likely to develop depression as people with low neuroticism.

The good news: we are finally talking about menopause! The not so good news: we still have a long way to go, especially in the realm of research, says this week's guest Dr. Stephanie Faubion, who is on the tip of the spear leading the way forward as the Medical Director of The North American Menopause Society (NAMS). When it comes to dealing with menopause openly in our culture, especially in the workplace, Dr. Faubion believes we are where we were with pregnancy 30 years ago. And she has some ideas on how we can all help accelerate progress and bring our doctors and culture up to speed.  Along with her role as Medical Director of NAMS, Dr. Faubion is Professor and Chair of the Department of Medicine at Mayo Clinic in Jacksonville, Florida, and Director of the Mayo Clinic Center for Women's Health. Her expertise is in women's health, clinical research, education, and clinical practice. You can learn more about her and her work at https://www.mayo.edu/research/faculty/faubion-stephanie-s-m-d-m-b-a/bio-20199366 (mayo.edu). Get your tickets to the Hit Play Not Pause Summit at https://www.feistymenopause.com/hit-play-not-pause-summit (feistymenopause.com/hit-play-not-pause-summit) Tickets are just $20! First 100 registrants get $10 off with the code HITPLAY.  **Support the Podcast**  InsideTracker: 20% off at http://insidetracker.com/feisty (insidetracker.com/feisty) Previnex: 15% off your first order with code HITPLAY at https://www.previnex.com/ (https://www.previnex.com/)  Bonafide: 20% off your first purchase when you subscribe to any product with code HITPLAY at  http://hellobonafide.com/hitplay (hellobonafide.com/hitplay) Nutrisense: Go to http://nutrisense.io/hitplay (nutrisense.io/hitplay) for $30 off any subscription to the CGM program This podcast uses the following third-party services for analysis: Podsights - https://podsights.com/privacy Chartable - https://chartable.com/privacy

Dr. Stephanie Faubion, medical director of the North American Menopause Society (NAMS), joins Lisa Dent on Chicago’s Afternoon News to explain a study done by the organization that suggests doctors will soon be able to predict when a woman will enter menopause. Follow Your Favorite Chicago’s Afternoon News Personalities on Twitter:Follow @LisaDentSpeaksFollow @SteveBertrand Follow @kpowell720 […]

In this episode we interview Dr. Stephanie Faubion about hormone therapy for the treatment of menopause symptoms.  We cover the new position statement released by NAMS about hormone therapy, what changed since the last position statement, how clinicians can frame conversations about hormone therapy, and where clinicians can learn more about providing hormone therapy. You can also still register for the NAMS Conference that is being held in Atlanta October 12-15, 2022. The post EP 61: Hormone Therapy with Dr. Stephanie Faubion appeared first on Woman Centered Health.

Jen talks to Dr. Stephanie Faubion, M.D., M.B.A, author of "The Menopause Solution" and Penny and Bill George Director for Mayo Clinic's Center for Women's Health and medical director for The North American Menopause Society - about how anxiety, stress & worry can spike during the 7-10 year perimenopause period and what to do about it. For more information on Jen Kirkman, the host of Anxiety Bites, please go here: https://jenkirkman.bio.link and to get the takeaways for this episode please visit: http://www.jenkirkman.com/anxietybitespodcast To send an email to the show write to anxietybitesweekly at gmail dot com Anxiety Bites is distributed by the iHeartPodcast Network and co-produced by Dylan Fagan and JJ Posway. See omnystudio.com/listener for privacy information.

Overall, women are 40% more likely to experience insomnia than men and the numbers are even higher during perimenopause and menopause. There are many reasons for sleepless nights mid-life (beyond hot flashes!) that often go undiagnosed. In this segment, I am joined by Dr. Stephanie Faubion, the Director for Mayo Clinic's Center for Women's Health, and the medical director for The North American Menopause Society.  Dr. Streicher and Dr. Faubion cover: If FRAGMENTED sleep is restorative sleep MEDICAL CONDITIONS that can occur because of chronic insomnia The impact of mid-life STRESS on sleep The role of ALCOHOL and CANNABIS on the ability to sleep OBSTRUCTIVE SLEEP APNEA What it is Atypical symptoms that occur in women Risk factors How it is diagnosed Treatment options  RESTLESS LEG SYNDROME What it is  Risk factors  How it is diagnosed  Treatment options  The pros and cons of various SLEEPING AIDS How an OVERACTIVE BLADDER contributes to insomnia Tips to improve your SLEEP HYGIENE How to find an expert in MENOPAUSE and WHY so many doctors are not trained in menopause Stephanie Faubion, MD Professor of Medicine, The Mayo Clinic Director of the Mayo Center for Women's Health Twitter: @StephFaubionMD North American Menopause Society (NAMS)  Menopause.org To find a certified menopause practitioner: https://portal.menopause.org/NAMS/NAMS/Directory/Menopause-Practitioner.aspx For more information on this topic:   Episode 2:Think Your Hot Flashes Can't Kill You? Think Again!  Episode 3: What's Up Down There? Genital Dryness & Misbehaving Bladders   Episode 5: Vaginal Estrogen- Rings, Creams, and Other Things   Episode 6: Your Post Menopause Urethra and Why You Should  Care- with Dr. Kelly Casperson Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Lauren Streicher, MD is a clinical professor of obstetrics and gynecology at Northwestern University's Feinberg School of Medicine, and the medical director of the Northwestern Medicine Center for Sexual Medicine and Menopause. She is a certified menopause practitioner of the North American Menopause Society.  Dr. Streicher is the medical correspondent for Chicago's top-rated news program, the WGNMorningNews, and has been seen on The Today Show, Good Morning America, The Oprah Winfrey Show, CNN, NPR, Dr.Radio,Nightline,Fox and Friends, The Steve Harvey Show, CBS ThisMorning,ABCNewsNow,NBCNightlyNews,20/20, and WorldNewsTonight. She is an expert source for many magazines and serves on the medical advisory board of The Kinsey Institute, Self Magazine and Prevention Magazine. She writes a regular column for The Ethel by AARP and Prevention Magazine.  Subscribe and Follow Dr. Streicher on  DrStreicher.com Instagram @DrStreich Twitter @DrStreicher Facebook  @DrStreicher YouTube  DrStreicherTV Books by Lauren Streicher, MD  Slip Sliding Away: Turning Back the Clock on Your Vagina-A gynecologist's guide to eliminating post-menopause dryness and pain Hot Flash Hell: A Gynecologist's Guide to Turning Down the Heat Sex Rx- Hormones , Health, and Your Best Sex Ever The Essential Guide to Hysterectomy

SHR # 2780:: HRT Gets The Green Light plus The Sex Factor in Blood Pressure Regulation - Dr. Stephanie Faubion, MD - Dr. Mykola Memenko, Ph.D. - Although hormone therapy (HT) remains the most effective treatment for menopause symptoms, some women have hesitated to use it because of concerns about various adverse health effects. A new study, however, is reducing some of those concerns, showing no increased risk of heart disease or type 2 diabetes relative to HT use. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS). PLUS - Another difference between females and males appears to be a key mechanism in how they become hypertensive, scientists say, and consequently which antihypertensives should be most effective for them. “There is cumulative evidence that while the fundamental system for blood pressure control is the same, blood pressure regulation in males and females is somewhat different,”

Mediterranean-style diets linked to better brain function in older adults American Geriatrics Society, July 26, 2021 Eating foods included in two healthy diets--the Mediterranean or the MIND diet--is linked to a lower risk for memory difficulties in older adults, according to a study published in the Journal of the American Geriatrics Society. The Mediterranean diet is rich in fruits, vegetables, whole grains, beans, potatoes, nuts, olive oil and fish. Processed foods, fried and fast foods, snack foods, red meat, poultry and whole-fat dairy foods are infrequently eaten on the Mediterranean diet. The MIND diet is a version of the Mediterranean diet that includes 15 types of foods. Ten are considered "brain-healthy:" green leafy vegetables, other vegetables, nuts, berries, beans, whole grains, seafood, poultry, olive oil, and wine. Five are considered unhealthy: red meat, butter and stick margarine, cheese, pastries, sweets and fried/fast foods. Researchers examined information from 5,907 older adults who participated in the Health and Retirement Study. The participants filled out questionnaires about their eating habits. Researchers then measured the participants' cognitive abilities--mostly on their memory and attention skills. The researchers compared the diets of participants to their performance on the cognitive tests. They found that older people who ate Mediterranean and MIND-style diets scored significantly better on the cognitive function tests than those who ate less healthy diets. In fact, older people who ate a Mediterranean-style diet had 35% lower risk of scoring poorly on cognitive tests. Even those who ate a moderate Mediterranean-style diet had 15% lower risk of doing poorly on cognitive tests. The researchers noted similar results for people who ate MIND-style diets. This study suggests that eating Mediterranean and MIND-style diets is linked to better overall cognitive function in older adults, said the researchers. What's more, older adults who followed these healthy diets had lower risks for having cognitive impairment in later life, noted the researchers.     Postmenopausal women can dance their way to better health New study suggests that dancing improves cholesterol levels, physical fitness, self-image, and self-esteem in postmenopausal women North American Menopause Society, July 28, 2021 Women often struggle with managing their weight and other health risk factors, such as high cholesterol, once they transition through menopause. A new study suggests that dancing may effectively lower cholesterol levels, improve fitness and body composition and in the process, improve self-esteem. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). After menopause, women are more likely to experience weight gain, overall/central body adiposity increases, and metabolic disturbances, such as increases in triglycerides and bad cholesterol. Together, these changes ultimately increase cardiovascular risk. Around this same time, women often are less physically active, which translates into reductions in lean mass and an increased risk of falls and fractures. As a result of all these changes, postmenopausal women often suffer from decreased self-image and self-esteem, which are directly related to overall mental health. Physical activity has been shown to minimize some of the many health problems associated with menopause. The effect of dancing, specifically, has already been investigated with regard to how it improves body composition and functional fitness. Few studies, however, have investigated the effects of dance on body image, self-esteem, and physical fitness together in postmenopausal women. This new study was designed to analyze the effects of dance practice on body composition, metabolic profile, functional fitness, and self-image/self-esteem in postmenopausal women. Although the sample size was small, the study suggested some credible benefits of a three-times-weekly dance regimen in improving not only the lipid profile and functional fitness of postmenopausal women but also self-image and self-esteem. Dance therapy is seen as an attractive option because it is a pleasant activity with low associated costs and low risk of injury for its practitioners. Additional confirmed benefits of regular dancing include improvement in balance, postural control, gait, strength, and overall physical performance. All of these benefits may contribute to a woman's ability to maintain an independent, high-quality lifestyle throughout her lifespan. Study results are published in the article “Dance practice modifies functional fitness, lipid profile, and self-image in postmenopausal women.” “This study highlights the feasibility of a simple intervention, such as a dance class three times weekly, for improving not only fitness and metabolic profile but also self-image and self-esteem in postmenopausal women. In addition to these benefits, women also probably enjoyed a sense of comradery from the shared experience of learning something new,” says Dr. Stephanie Faubion, NAMS medical director.     Impact of vitamin D on response to anti-tumor necrosis factor-alpha therapy in children with inflammatory bowel disease Massachusetts General Hospital for Children, July 20, 2021 According to news reporting originating in Boston, Massachusetts, research stated, “Experimental studies have shown that vitamin D has an immunomodulatory effect on the innate and adaptive immune systems. Associations between vitamin D deficiency and development or progression of inflammatory bowel diseases (IBDs) are reported, but a cause-and-effect relationship between pretreatment 25 hydroxyvitamin D [25(OH)D] levels and response to anti-tumor necrosis factor-alpha (anti-TNF) therapy is not established.” The news reporters obtained a quote from the research from MassGeneral Hospital for Children, “This retrospective study evaluated pediatric IBD patients who had 25(OH)D levels drawn within 3 months of initiating infliximab and/or adalimumab treatment. Demographic features, Paris classification, baseline 25(OH)D levels, disease activity, and laboratory results before and after 3 months of anti-TNF therapy were collected. The interaction between vitamin D insufficiency at induction and lack of response to anti-TNF therapy at 3 months was determined. Of the 383 patients, 76 met inclusion criteria. Sixty-five patients (85.5%) had Crohn disease (CD) and 11 (14.5%) had ulcerative colitis. Seven patients had 25(OH)D levels obtained during both infliximab and adalimumab induction; hence 83 subjects were evaluated (infliximab: 70 patients, adalimumab: 13 patients). 25(OH)D

Hot flashes. Night sweats. Mood swings. We're talking menopause with Dr. Stephanie Faubion, one the nation's top experts and the Director for Mayo Clinic's Center for Women's Health. Dr. Faubion shares some of her most recent findings from her research and how we can ameliorate some of the symptoms we face from menopause.

The Gary Null Show is here to inform you on the best news in health, healing, the environment. Intense light may boost heart health A novel use of intense light therapy may help decrease the tissue damage experienced during heart attacks, reveals new research in mice.  University of Colorado, August 19, 2020 The study, out of the University of Colorado and appearing in the journal Cell Reports, shows that exposing lab mice to intense light for a week improved their outcomes after heart attacks. The research also suggests that this procedure could benefit humans, and the researchers outline the reason why. “We already knew that intense light can protect against heart attacks, but now we have found the mechanism behind it,” says the study's senior author Dr. Tobias Eckle, professor of anesthesiology at the University of Colorado School of Medicine in Aurora. Boosting specific gene protects heart In the study, the researchers discovered that intense light influences the functions of the PER2gene, which is expressed by a part of the brain that controls circadian rhythms. By boosting this gene through intense light therapy, the researchers discovered that the mice's heart tissue received extra protection when it experienced issues with oxygen, such as during a heart attack. Additionally, this intense light also heightened cardiac adenosine, which is a specialized chemical that helps with blood flow regulation. In concert, both benefits helped protect heart health. Also, when they studied the mice, the researchers found that being able to physically perceive light was vital, as blind mice experienced no benefits from the intense light. Humans had similar benefits The next step was to see if humans could benefit from light therapy. The researchers worked with healthy human volunteers and exposed them to 30 minutes of intense light. On five consecutive mornings, the researchers exposed the participants to 10,000 lumens of light and drew blood several times. The researchers found that PER2 levels increased in response to light therapy in the human participants as it did in the mice. They also reported that the human volunteers saw a decreased level of plasma triglycerides and improved metabolism.  Dr. Eckle explained that light plays an essential part in human health, not only in regulating the circadian rhythm but in cardiovascular health as well. He adds that according to prior studies, more people throughout the U.S. experience heart attacks during the darker months of winter, even in states that traditionally get more sunshine, such as Hawaii and Arizona.   Study: Supplementation with curcumin offers benefits for patients with metabolic syndrome Coventry University (UK) and Tehran University of Medical Sciences (Iran), August 19, 2020   A study published in the journal Diabetes and Metabolic Syndrome: Clinical Research and Review found that curcumin supplementation can help increase adiponectin levels. Adiponectin is said to help reduce the risk of cardiometabolic disease. According to researchers from the United Kingdom and Iran, people with metabolic syndrome and metabolic disorders can benefit from taking curcumin supplements regularly. Curcumin is the main active component of turmeric, an herb that offers plenty of health benefits. Increased levels of adiponectin through curcumin supplementation Adiponectin is a hormone produced exclusively by adipocytes, or fat cells. It plays a role in insulin response and has anti-inflammatory effects. In fact, low blood levels of adiponectin are linked to cardiovascular diseases, insulin resistance, obesity and dyslipidemia — a condition characterized by abnormal levels of lipids in the blood. In the study, the researchers examined the effect of curcumin on blood adiponectin levels. They reviewed six randomized clinical trials on curcumin, in which 652 participants were included. Data analysis revealed that, compared with a placebo, curcumin supplementation significantly raised adiponectin levels. In trials that lasted longer, the researchers observed greater effects on adiponectin. “We were able to confirm the veracity of a number of independent studies, highlighting that curcumin supplementation, particularly when consumed for less than 10 weeks, may significantly increase adiponectin levels, even when controlling for numerous biological and sociological variables,” wrote the researchers. People with metabolic syndrome, in particular, will find curcumin supplementation useful. Metabolic syndrome refers to a cluster of diseases such as diabetes, hypertension and obesity.      Study finds physical activity is beneficial for health, and more intense activity is better Cambridge University, August 18, 2020 Physical activity of any intensity is beneficial for health, but more intense activity has greater benefits, according to a new study published today in Nature Medicine. In the largest study to date of accelerometer-measured physical activity, a team led by researchers at the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge analyzed data from more than 96,000 UK Biobank participants. Current physical activity guidelines from the UK Chief Medical Officers recommend that adults should aim to be active every day, and also that adults should undertake 150 minutes of moderate intensity activity (equivalent to a brisk walk) or 75 minutes of vigorous intensity activity (such as running) every week. Previous research has shown that moderate and vigorous intensity activity confers greater health benefits than light intensity activity, but it has not been clear if this is because it makes a greater contribution to the total amount of physical activity, or if it has additional health benefits beyond this. A challenge facing researchers has been that the low intensity, incidental movement that accumulates in the course of everyday activities is very hard to recall accurately, and consequently difficult to measure using questionnaires. Wearable devices have enabled better detection of this type of movement that makes up the majority of our daily physical activity, but until now have not been used on a large enough scale to determine if more intense activity makes a contribution to health, distinct from increasing total volume.  The researchers used data from 96,476 middle-aged adults in Great Britain to investigate whether activity of moderate intensity or above contributed to a lower risk of death over and above its contribution to total volume of activity. These individuals wore a research-grade activity tracker on their dominant wrist for a week as part of their participation in the UK Biobank study. The researchers used the data on the duration and intensity of movement collected to calculate the total volume of activity, expressed as physical activity energy expenditure (PAEE). The researchers also determined the percentage of that volume that was achieved through moderate and vigorous intensity activity. The UK Biobank participants had an average PAEE of 40 kJ/kg/day, a third of which was from activity of at least moderate intensity, again on average. Owing to the large scale of the study, there was much variation in the underlying intensity contributions to similar volume levels. The researchers examined if physical activity levels were associated with the risk of death in the follow-up period of on average 3.1 years. During this time 732 of the 96, 476 participants died, though the researchers excluded those who died within the first year from their analysis, and took existing conditions such diabetes, heart disease, and cancer into account as these might reduce physical activity. Expending more energy of any intensity was strongly associated with a lower risk of death over the following three years. Participants who accumulated 20 kJ/kg/day through physical activity were a third less likely to die compared to those who accumulated 15 kJ/kg/day, when the proportion from at least moderate intensity activity was 10% in both cases. The additional activity is the equivalent to a 35-minute stroll, with an extra two minutes at a brisker pace. Those who accumulated 30 kJ/kg/day were about half as likely to die in the follow-up period compared to those who accumulated 15 kJ/kg/day, when the proportion from at least moderate intensity activity was 10% in both cases. However, if this volume of 30 kJ/kg/day included 30% from at least moderate intensity activity, then they were only about a quarter as likely to die. The difference between this scenario and the reference of 15 kJ/kg/day and 10% is equivalent to an hour's stroll plus 35 minutes at a brisker pace. Dr. Tessa Strain of the MRC Epidemiology Unit, and lead author on the paper, said: "Our results show that doing more activity of any intensity is beneficial, but that expending those calories in more intense activity is better still. By gradually building up the intensity of physical activity we do each day we can improve our future health." Dr. Søren Brage, also at the MRC Epidemiology Unit and senior author on the paper, added: "Our research shows how the use of wearable devices capable of measuring physical activity in large cohorts can help disentangle the roles of volume and intensity of activity in influencing future health. The availability of data from nearly 100,000 participants in UK Biobank, backed up by a series of validation studies, allowed us to compare the impact of activity intensity in groups with similar overall volumes of physical activity, and demonstrate that more intense physical activity has health benefits beyond just contributing to total activity volume. Our results also show that activity volumes accumulated almost exclusively through light activity could still halve the mortality risk. Taken together, this means that there are several different pathways to maintain good health and people can choose the path that works best for them."   High blood pressure during pregnancy may mean worse hot flashes during menopause Mayo Clinic, August 19, 2020   Women with a history of high blood pressure disorders during pregnancy are more likely to experience bothersome menopausal symptoms such as hot flashes and night sweats, according to a study published Wednesday, Aug. 19, in Menopause: The Journal of the North American Menopause Society. "We already know that women with high blood pressure during pregnancy or those who experience menopause symptoms such as hot flashes and night sweats have a higher risk of developing heart disease. Our research discovered that women who experienced high blood pressure during pregnancy were much more likely to experience bothersome menopausal symptoms, including hot flashes and night sweats during menopause," says Stephanie Faubion, M.D., the study's lead author. Dr. Faubion is the Penny and Bill George Director for Mayo Clinic's Center for Women's Health. Researchers analyzed the medical records of 2,684 women ages 40 to 65 who were seen for specialty menopause or sexual health consultations at women's health clinics at Mayo Clinic in Rochester, Minnesota, and Mayo Clinic in Scottsdale, Arizona, between May 2015 and September 2019. All study participants completed a questionnaire in which they self-reported their menopause symptoms and effects of these symptoms on their quality of life. Study participants also completed questionnaires that documented whether they experienced high blood pressure disorders during pregnancy, such as preeclampsia or gestational hypertension. Researchers discovered a significant association between women with a history of high blood pressure disorders during pregnancy who reported more bothersome menopausal symptoms. Women with this high blood pressure history using hormone therapy also reported more menopausal symptoms, compared to women with no history of high blood pressure disorders during pregnancy. Dr. Faubion says more research is needed to understand why there is a link between high blood pressure disorders during pregnancy and more severe menopausal symptoms. But one thing is clear: Physicians need to do a better job monitoring women who experience high blood pressuring during pregnancy after they give birth. "We know medical providers have historically done a lousy job identifying and following women with histories of high blood pressure disorders during pregnancy, despite knowing that they have a higher heart disease risk," says Dr. Faubion. "This study is another reminder that these women are different. It is important that they not only receive education with regard to what they may experience during menopause, but also that they undergo routine screenings and counseling on how they can reduce their risk for heart disease."   Oxidative stress a significant contributor to COPD and idiopathic pulmonary fibrosis Justus-Liebig University (Germany), August 17, 2020   According to news reporting originating from Giessen, Germany, research stated, “Healthy ageing of the lung involves structural changes but also numerous cell-intrinsic and cell-extrinsic alterations. Among them are the age-related decline in central cellular quality control mechanisms such as redox and protein homeostasis.” Our news editors obtained a quote from the research from Justus-Liebig-University Giessen, “In this review, we would like to provide a conceptual framework of how impaired stress responses in the ageing lung, as exemplified by dysfunctional redox and protein homeostasis, may contribute to onset and progression of COPD and idiopathic pulmonary fibrosis (IPF). We propose that age-related imbalanced redox and protein homeostasis acts, amongst others (e.g. cellular senescence), as a ‘first hit' that challenges the adaptive stress-response pathways of the cell, increases the level of oxidative stress and renders the lung susceptible to subsequent injury and disease. In both COPD and IPF, additional environmental insults such as smoking, air pollution and/or infections then serve as ‘second hits' which contribute to persistently elevated oxidative stress that overwhelms the already weakened adaptive defence and repair pathways in the elderly towards non-adaptive, irremediable stress thereby promoting development and progression of respiratory diseases.” According to the news editors, the research concluded: “COPD and IPF are thus distinct horns of the same devil, ‘lung ageing.”     Citrus fruits could help prevent obesity-related heart disease, liver disease, diabetes Universidade Estadual Paulista  (Brazil), August 11, 2020    Oranges and other citrus fruits are good for you—they contain plenty of vitamins and substances, such as antioxidants, that can help keep you healthy. Now a group of researchers reports that these fruits also help prevent harmful effects of obesity in mice fed a Western-style, high-fat diet.   The researchers are presenting their work today at the 252nd National Meeting & Exposition of the American Chemical Society (ACS). ACS, the world's largest scientific society, is holding the meeting here through Thursday. It features more than 9,000 presentations on a wide range of science topics.   "Our results indicate that in the future we can use citrus flavanones, a class of antioxidants, to prevent or delay chronic diseases caused by obesity in humans," says Paula S. Ferreira, a graduate student with the research team.   More than one-third of all adults in the U.S. are obese, according to the U.S. Centers for Disease Control and Prevention. Being obese increases the risk of developing heart disease, liver disease and diabetes, most likely because of oxidative stress and inflammation, Ferreira says. When humans consume a high-fat diet, they accumulate fat in their bodies. Fat cells produce excessive reactive oxygen species, which can damage cells in a process called oxidative stress. The body can usually fight off the molecules with antioxidants. But obese patients have very enlarged fat cells, which can lead to even higher levels of reactive oxygen species that overwhelm the body's ability to counteract them.   Citrus fruits contain large amounts of antioxidants, a class of which are called flavanones. Previous studies linked citrus flavanones to lowering oxidative stress in vitro and in animal models. These researchers wanted to observe the effects of citrus flavanones for the first time on mice with no genetic modifications and that were fed a high-fat diet.   The team, at Universidade Estadual Paulista (UNESP) in Brazil, conducted an experiment with 50 mice, treating them with flavanones found in oranges, limes and lemons. The flavanones they focused on were hesperidin, eriocitrin and eriodictyol. For one month, researchers gave groups either a standard diet, a high-fat diet, a high-fat diet plus hesperidin, a high-fat diet plus eriocitrin or a high-fat diet plus eriodictyol.   The high-fat diet without the flavanones increased the levels of cell-damage markers called thiobarbituric acid reactive substances (TBARS) by 80 percent in the blood and 57 percent in the liver compared to mice on a standard diet. But hesperidin, eriocitrin and eriodictyol decreased the TBARS levels in the liver by 50 percent, 57 percent and 64 percent, respectively, compared with mice fed a high-fat diet but not given flavanones. Eriocitrin and eriodictyol also reduced TBARS levels in the blood by 48 percent and 47 percent, respectively, in these mice. In addition, mice treated with hesperidin and eriodictyol had reduced fat accumulation and damage in the liver.   "Our studies did not show any weight loss due to the citrus flavanones," says Thais B. Cesar, Ph.D., who leads the team. "However, even without helping the mice lose weight, they made them healthier with lower oxidative stress, less liver damage, lower blood lipids and lower blood glucose." Ferreira adds, "This study also suggests that consuming citrus fruits probably could have beneficial effects for people who are not obese, but have diets rich in fats, putting them at risk of developing cardiovascular disease, insulin resistance and abdominal obesity."   Next, the team will explore how best to administer these flavanones, whether in citrus juice, by consuming the fruit or developing a pill with these antioxidants. In addition, the team plans to conduct studies involving humans, Cesar says.     Researchers find link between gut microbiome and cancer treatment outcomes Study highlights positive impact of microbial diversity on immunotherapy response and suggests that cancer patients should eat a high-fiber diet with fruits, vegetables and grains with resistant starches. City of Hope Hospital, August 19, 2020   Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens. Their findings are outlined in a study published today in the journal European Urology. "We also reported the changes over time in the gut microbiome that occur during the course of therapy -- the cumulative findings from our report open the door to therapies directed at the microbiome," said Sumanta Pal, M.D., one of the study's senior authors and co-director of the Kidney Cancer Program at City of Hope, a world-renowned independent research and treatment center for cancer, diabetes and other life-threatening diseases. The gut microbiome is composed of microbes like bacteria and viruses that reside in the gastrointestinal tract. In recent years, an increase in knowledge about the microbiome in relation to general health has led to deeper explorations of its role in disease states, as well as how the organisms may interact with treatments.  "Previous studies have suggested a relationship between the gut microbiome and response to immunotherapy in solid tumors, including metastatic kidney cancer," said Nicholas Salgia, B.Sc., a clinical research assistant at City of Hope and the paper's lead author. "The results from our study build on earlier findings and reaffirm that the diversity and composition of patients' microbiomes are associated with clinical responses to anti-cancer therapies."  The study, which collected data from 31 people with metastatic kidney cancer, features the first reports of comparing microbiome sequencing at different time points in cancer patients. Participants were asked to provide up to three stool samples: at baseline, four weeks into therapy and 12 weeks into therapy.  Using the clinical trial results, the team was able to identify changes in the microbiome over time in kidney cancer patients receiving immunotherapy. The findings found that a greater variety of organisms was associated with a benefit to the patients, and also suggested that modulating the gut microbiome during the course of treatment may impact responses to therapy.  "The patients with the highest benefit from cancer treatment were those with more microbial diversity, but also those with a higher abundance of a specific bacterium known as Akkermansia muciniphila," said Sarah Highlander, Ph.D., a research professor in TGen's Pathogen and Microbiome Division and one of the study's senior authors. "This organism has been associated with benefit in other immunotherapy studies."  Highlander says one potential takeaway is that oncologists might encourage patients to pay attention to their gut microbiome by eating a high-fiber diet, including fruits and vegetables high in fructo-oligosaccharides such as bananas, dried fruit, onions, leeks, garlic, asparagus and artichokes, as well as grains with resistant starches such as barley or uncooked potato starch, for example. Highlander says that next steps should include expanding the relatively small study to a much larger group of patients that are followed over a longer time period. At City of Hope, researchers have already embarked on a clinical trial to further explore the idea that modulating the microbiome during therapy could have an impact on clinical outcomes.  "We have randomized patients with metastatic kidney cancer to receive a probiotic supplement in addition to an FDA-approved immunotherapy regimen or the immunotherapy alone," explained Salgia. "This work provided a strong framework for such a study."  The collaborations between clinical experts at City of Hope and basic science colleagues at TGen have contributed to advancements in the understanding of not just the microbiome, but also in cancer biology and clinical outcomes at large.  "Our strong relationship with the microbiome team at TGen has fruitfully produced novel insights into the clinical implications of the microbiome in kidney cancer, among other cancer types," said Pal, who is an internationally recognized leader in the area of genitourinary cancers.  Just last month, City of Hope and TGen launched a project to use one of the world's most comprehensive genomic analysis tools to map out personalized treatment plans for metastatic kidney cancer patients. "This current study is a further testament to the collaborative research structure we've developed between the affiliate institutions," said Pal. "Through these collaborations we can implement both a bench-to-bedside and bedside-to-bench research model that will lead to better patient care at City of Hope through access to clinical trials and precision medicine approaches."     Antiapoptotic effects of carotenoids in neurodegeneration University of Alabama, August 17, 2020 According to news reporting out of the University of Alabama research stated, “Apoptosis, programmed cell death type I, is a critical part of neurodegeneration in cerebral ischemia, Parkinson's, and Alzheimer's disease.” Our news journalists obtained a quote from the research from University of Alabama: “Apoptosis begins with activation of pro-death proteins Bax and Bak, release of cytochrome c and activation of caspases, loss of membrane integrity of intracellular organelles, and ultimately cell death. Approaches that block apoptotic pathways may prevent or delay neurodegenerative processes. Carotenoids are a group of pigments found in fruits, vegetables, and seaweeds that possess antioxidant properties. Over the last several decades, an increasing number of studies have demonstrated a protective role of carotenoids in neurodegenerative disease. In this review, we describe functions of commonly consumed carotenoids including lycopene, b-carotene, lutein, astaxanthin, and fucoxanthin and their roles in neurodegenerative disease models.” According to the news reporters, the research concluded: “We also discuss the underlying cellular mechanisms of carotenoid-mediated neuroprotection, including their antioxidant properties, role as signaling molecules, and as gene regulators that alleviate apoptosis-associated brain cell death.”

Kathryn interview science journalist Kayt Sukel, author of “The Art of Risk: The New Science of Courage, Caution and Chance”. Are risk-takers born or made? This is the question that set Sukel on a quest to find the answers, blending case studies and hard-hitting science to explore risk-taking in work, play, love and life and showing readers how understanding their own behavior can further their personal success. Sukel's work appears in the Atlantic Monthly, New Scientist, USA Today, The Washington Post and Parenting. Kathryn also interviews women's health expert Dr. Stephanie Faubion, author of “Mayo Clinic's The Menopause Solution: A Doctor's Guide to Relieving Hot Flashes, Enjoying Better Sex, Sleeping Well, Controlling Your Weight, and Being Happy!” Dr. Faubion presents a balanced, unbiased overview of what to expect in midlife and beyond. Dr. Faubion is an Assistant Professor of Medicine and director of the Office of Women's Health and the Women's Health Clinic at the Mayo Clinic.

Kathryn interview science journalist Kayt Sukel, author of “The Art of Risk: The New Science of Courage, Caution and Chance”. Are risk-takers born or made? This is the question that set Sukel on a quest to find the answers, blending case studies and hard-hitting science to explore risk-taking in work, play, love and life and showing readers how understanding their own behavior can further their personal success. Sukel's work appears in the Atlantic Monthly, New Scientist, USA Today, The Washington Post and Parenting. Kathryn also interviews women's health expert Dr. Stephanie Faubion, author of “Mayo Clinic's The Menopause Solution: A Doctor's Guide to Relieving Hot Flashes, Enjoying Better Sex, Sleeping Well, Controlling Your Weight, and Being Happy!” Dr. Faubion presents a balanced, unbiased overview of what to expect in midlife and beyond. Dr. Faubion is an Assistant Professor of Medicine and director of the Office of Women's Health and the Women's Health Clinic at the Mayo Clinic.

A study recently conducted at Mayo Clinic found that women who had high blood pressure during pregnancy were more likely to experience bothersome menopausal symptoms like hot flashes and night sweats. Hypertensive disorders in pregnancy and hot flashes are both linked to heart disease risk. On the Mayo Clinic Q&A podcast, Dr. Stephanie Faubion, the study's lead author, will discuss the key takeaways from the study and explain where more research is needed. Dr. Faubion is the Penny and Bill George Director for Mayo Clinic's Center for Women's Health. Advertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy