Podcasts about uroc

2025 marks the centenary year of Malcolm X's birth. For the occasion, Dr. Rose Brewer, Thandisizwe Jackson-Nisan and additional planners have organized an event uplifting the politics and vision of Malcolm X. The event is on Saturday, May 17 at UROC at Plymouth and Oliver. The event is described in the promotional materials as gathering of "conscious minds that will include panel discussion, break out groups and vegan food!"  Dr. Rose Brewer is a Morse Alumni Distinguished Teaching Professor and Past Chair Person of the Department of African American and African Studies at the University of Minnesota-Twin Cities. She took the time to hop on a ZOOM with Sean McPherson from Jazz88 to talk about the event, provide some modern context for X's impact and point listeners to some additional material if they want to learn more about Malcolm X. 

2025 marks the centenary year of Malcolm X's birth. For the occasion, Dr. Rose Brewer, Thandisizwe Jackson-Nisan and additional planners have organized an event uplifting the politics and vision of Malcolm X. The event is on Saturday, May 17 at UROC at Plymouth and Oliver. The event is described in the promotional materials as gathering of "conscious minds that will include panel discussion, break out groups and vegan food!"  Dr. Rose Brewer is a Morse Alumni Distinguished Teaching Professor and Past Chair Person of the Department of African American and African Studies at the University of Minnesota-Twin Cities. She took the time to hop on a ZOOM with Sean McPherson from Jazz88 to talk about the event, provide some modern context for X's impact and point listeners to some additional material if they want to learn more about Malcolm X. 

If it has an acronym, Chris May has probably raced there – KOH, ECORS, UROC, WE Rock, XRRA – it's been a long road and now he's started on the next generation of racers. Great stories of a couple of guys with high-budget dreams and low-budget pockets; it's a fun listen. Be sure to tune in on your favorite podcast app.5:52 – My dad was like, “you do not want to work on cars, that's a bad profession”12:08 – don't ever take your vehicle to a WalMart, we tore up so many vehicles goofing around                                19:52 – we entered Tuff Truck, our vehicles kind of sucked, but we entered anyway 24:16 – being in South Carolina, we didn't learn about a lot of stuff til later on32:15 – I got to do something easier so I have energy to go work after work50:08 – Drew got an invite to the OG race, be he was like, my dad's never going to pay for that much gas to go to California52:14 – When everybody went off the line, I just followed the last guy and took off59:28 – my daughter is racing the kids stuff, and it's kind of short course1:10:46 – Keep it real, it makes it less stressful and you can have more funSpecial thanks to 4low Magazine and Maxxis Tires for support and sponsorship of this podcast.Be sure to listen on your favorite podcast app.Support the show

Estos actores, autores y directores lo han sido todo en el teatro español. Juntos y separados. Juntos se iniciaron en el teatro independiente, con la Compañía UROC, y al bajarse de las tablas siguieron juntos, en matrimonio. Separados, Margallo formó parte de compañías históricas como la del Teatro Lope de Vega o el María Guerrero, y Martínez empezó a ampliar su traectoria en cine y televisión, obteniendo incluso en un Premio Feroz. El premio les ha cogido separados. A él rodando, con el teléfono apagado, a ella en tren y atendiendo la llamada del Ojo Crítico. Como un chute vitamínico en medio del bajón que todos estamos viviendo. Así le ha sentado a la escritora Liudmila Ulítskaya el Premio Formentor, que le será entregado en las Palmas de Gran Canaria. Un premio decidido antes de que empezara la guerra de Ucrania y que valora a esta escritora rusa, de orígenes judíos y también ucranianos, como una heredera de la gran tradición de narradores de su país y subraya su capacidad para crear personajes que superan la adversidad. Ángela Núñez ha hablado con él. Quizás podamos ser la misma persona después de ser padres. Sabemos que Jesús Marchamalo no lo es y que el escritor con el que ha dado su paseo literario de esta semana, tampoco. Vamos a hablar con Eduardo Halfón de 'Un hijo cualquiera', también de las fortalezas y vulnerabilidades de la paternidad. De infancia, muerte, desarraigo y búsqueda de identidad. Es una de las grandes pintoras españolas del siglo XX. No suficientemente reconocida. Parte de los realistas madrileños junto a Antonio López, Isabel Quintanilla, María Moreno o Lucio Muñoz, su marido. Aunque el de Amalia Avia era un realismo ensoñador. Una gran retrospectiva en Alcalá 31, en Madrid, recorre toda su carrera. Lo cuenta Sonia Castelani. Parecía que la discografía de La buena vida iba a estar, por fin, disponible en plataformas. Pero fue sólo un espejismo. Ni el sello ni la banda habían tomado la decisión de incorporarlo a plataformas por lo que, cuando apareció, denunciaron la subida. Leyre Guerrero nos enseña a bandas herederas de ese sonido Donostia.   Escuchar audio

If you have run an ultra/trail race in WV, VA, or Pennsylvania, you have likely run with a man named Brandon Perry. Brandon is one of the most fun loving, friendliest, hardest working, and all around greatest guys to be around. In this episode, we dive in to his little known backstory where he details the struggles of being overweight and his journey to transform himself both physically and mentally to be the ultrarunner he is today. Brandon has completed over 30 ultra races including Grindstone 100 mile, Hellgate 100k, UROC 100k, Ironstone 100k, Georgia Death Race, and so many more. Through ultrarunning, we all meet amazing people who give us wisdom and guidance and Brandon is certainly one of those people for me. It is awesome to see him accomplish some amazing feats but even more awesome to watch him become an inspiration for members of the black community who want to become runners. He is breaking barriers and constantly is showing that all people can enjoy the trails. This sport means so much to Brandon and he hopes that everyone finds the same joy that this sport has given him. I hope you guys enjoy this episode!

After a long break from racing, Aliza Lapierre won the UROC 100k in Virginia last weekend. In this interview, Aliza talks about what it was like to get back into racing after such a long break, if the competitive experience has evolved for her, and how she embraced adventure running with friends during the COVID-19 pandemic.

After a long break from racing, Aliza Lapierre won the UROC 100k in Virginia last weekend. In this interview, Aliza talks about what it was like to get back into racing after such a long break, if the competitive experience has evolved for her, and how she embraced adventure running with friends during the COVID-19 pandemic.

Paul J. Wang: Welcome to the monthly podcast! On the Beat for Circulation: Arrhythmia and Electrophysiology. I'm Dr. Paul Wang, Editor-in-Chief. With some of the key highlights from this month's issue. Paul J. Wang: In our first paper, Demilade Adedinsewo and associates assess the accuracy of an artificial intelligence-enabled electrocardiogram [AI-ECG] to identify patients presenting with dyspnea who have left ventricular LV systolic function (defined as LV ejection fraction ≤35%) in the emergency department [ED]. Patients were included if they had at least one standard 12-lead electrocardiogram [ECG] acquired on the date of the ED visit and an echocardiogram performed within 30 days of presentation. Patients with prior LV systolic dysfunction were excluded. A total of 1,606 patients were included. Meantime from ECG echocardiogram was one day. The AI-ECG algorithm identified LV systolic dysfunction with an area under the curve [AUC] of 0.89 and accuracy of 85.9%. Sensitivity was 74%, specificity 87%, negative predictive value 97%, and positive predictive value 40%. To identify an ejection fraction less than 50%, the AUC was 0.85, sensitivity 86%, sensitivity 63%, and specificity 91%. NT-proBNP alone with a cutoff greater than 800 identified LV systolic function with an AUC of 0.80 by comparison. Paul J. Wang: In our next paper, Mahmood Alhusseini and associates hypothesize that convolutional neural networks [CNN] may enable objective analysis of intracardiac activation in atrial fibrillation [AF]. They perform panoramic recording of bi-atrial electrical signals in AF and use the Hilbert-transform to produce 175,000 image grids in 35 patients labeled for a rotational activation by experts who showed consistency, but with variability (kappa [κ]=0.79). In each patient, ablation terminated atrial fibrillation. A CNN was developed and trained on 100,000 AF image grids validated on 25,000 grids, and then tested on a separate 50,000 grids. They found in a separate test cohort of 50,000 grids, CNN reproducibly classified AF image grids into those with or without rotational sites with 95.0% accuracy. This accuracy exceeded that of support vector machines, traditional linear discriminant, and k-nearest neighbor statistical analyses. To probe the CNN, they applied gradient weighted class activation mapping, which revealed that the decision logic closely mimicked rules used by experts (C statistic 0.96). The authors concluded that convolutional neural networks improve the classification of intercardiac AF maps compared to other analyses and agreed with expert evaluation. Paul J. Wang: In our next paper, Kenji Okubo and associates examined whether late potential LP, abolition and ventricular tachycardia [VT] non-inclusive ability predicted long-term outcomes in patients with non-ischemic cardiomyopathy [NICM] undergoing VT ablation. The total 403 patients with NICM (523 procedures) who underwent VT ablation from 2010 to 2016 were included. The underlying structural disease consists of dilated cardiomyopathy (DCM, 49%), arrhythmogenic right ventricular cardiomyopathy (ARVD 17%), postmyocarditis (14%), valvular heart disease (8%), congenital heart disease (2%), hypertrophic cardiomyopathy (2%), and others (5%). Epicardial access was performed in 57% of patients. At baseline, the LPs were present in 60% of patients, and a VT was either inducible or sustained/incessant in 85% of the cases. At the end of the procedure LP abolition was achieved in 79% of cases in VT noninducability in 80%. After a multivariate analysis, the combination of LP abolition and VT noninducibility was independently associated with free survival from VT (hazard ratio, 0.45, p = 0.0002) and cardiac death (hazard ratio 0.38, P = 0.005). The benefit of LP abolition of preventing the VT recurrence in ARVD and postmyocarditis appeared superior to that observed for DCM. Paul J. Wang: In our next paper, Domenico Corradi, Jeffrey Saffitz and associates hypothesize that structural molecular changes in atrial myocardium that correlate with myocardial injury and precede and predict postoperative atrial fibrillation [POAF] may identify new molecular pathways and targets for prevention of this common morbid complication. Right atrial appendage [RAA] samples were prospectively collected during cardiac surgery from 239 patients enrolled in the OPERA trial. 35.2% of patients experienced POAF compared to the non-POAF group. They were significantly older and more likely to have chronic obstructive pulmonary disease or heart failure. They had a higher Euro score and more often underwent valve surgery. No differences in atrial size were observed between POAF and non-POAF patients. The extent of atrial interstitial fibrosis, cardiomyocyte myocytolysis, cardiomyocyte diameter, glycogen storage, or connection 43 distribution at the time of surgery, was not significantly associated with the incidents of POAF. None of these histopathological abnormalities were correlated with level of NT pro-BNP, hs-cTnT, CRP, or oxidative stress biomarkers. The authors concluded that in sinus rhythm patients undergoing cardiac surgery, histopathological changes in RAA do not predict POAF. They did not also correlate with biomarkers of cardiac function, inflammation, and oxidative stress. Paul J. Wang: In our next paper, Mark McCauley, Liang Hong, Arvind Sridhar, and associates hypothesize that obesity decreases sodium channel NAF 1.5 expression via enhanced oxidative stress, thus reducing the sodium current and enhancing susceptibility to atrial fibrillation [AF]. They studied a diet induced obese [DIO] mouse model. Pacing induced AF in 100% of DIO mice versus 25% in controls (P 20 ms shorter than the other sites, and/or induction of AF/atrial tachycardia during measurements. LVA ablation was performed in the LA-LVA patients during the follow-up period of a mean of 62 weeks, the EP test-guided group had a significantly lower recurrence rate (19%,11/57 versus 41%, 22/54, P=0.012) and a higher Kaplan-Meier AF/AT-free survival curve compared with controls (P=0.01). No significant differences in the recurrence, and AF/AT-free survival curves between PWI (positive EP test) and non-PWI (negative EP test) subgroups were observed. Therefore, PWI for positive EP tests reduced the AF/AT recurrence in the EP test-guided group. A stepwise Cox proportional hazard analysis identified EP test-guided ablation as a factor, reducing recurrence rates. The recurrence rates in LA-LVA ablation group and EP test-guided group were similar. Paul J. Wang: In our next study, Jinxuan Lin and associates assess whether simultaneous pacing of the left and right bundle branch areas may achieve more synchronous ventricular activation than just bundle pacing alone. In symptomatic bradycardia patients, the distal electrode of the bipolar pacing lead was placed at the left bundle branch area via a transventricular-septal approach. This was used to pace the left bundle branch area, while the ring electrode was used to pace the right bundle branch area. Bilateral bundle branch area pacing [BBBP] was achieved by stimulating the cathode and anode in various configurations. BBBP was successfully performed in 22 out of 36 patients. Compared with LBBP, BBBP resulted in greater shortening of QRS duration (109.3 vs 118.4 ms, P < 0.001). LBBP resulted in paced RBBB configuration with a DRVAT of 115 ms and interventricular conduction delay of 34.0 ms. BBBP fully resolved the RBBB morphology in 18 patients. In the remaining 4 patients, RBBP pacing partially corrected the right bundle branch block. Paul J. Wang: In our next paper, Ramanathan Parameswaran, Jonathan Kalman, Geoffrey Lee and associates recorded 2-minute long segments of simultaneous inter-operative mapping of endo- and epicardial lateral right atrial [RA] wall in patients with persistent atrial fibrillation [AF] using 2 high-density grid catheters (16 electrodes, 3 mm spacing). Filtered unipolar and bipolar electrograms [EGMS] of continuous 2-minute AF recordings and electrodes locations were exported for phase analysis. They defined endocardial-epicardial dissociation [EED] as phase differences of ≥20 ms between paired endo- and epi electrodes. Wavefronts [WF] were classified as single rotations, that is single wavefront, focal waves, or disorganized activity as per standard criteria. Endo-Epi wave fronts were simultaneously compared on dynamic phase maps. Complex fractionated electrograms were defined as bipolar electrograms with directional changes occupying at least 70% of the sample area. 14 patients with persistent AF underwent cardiac surgery are included. EED was seen in 50.3% of phase maps with significant temporal heterogeneity. Disorganized activity (endo 41.3%, epi 46.8%, P = 0.0194) and single wave (endo 31.3 versus epi 28.1, P = 0.129) were the dominant patterns. Transient rotations (endo 22%, epi 19.2%, P = 0.169, mean duration 590 ms) and non-sustained focal waves (endo 1.2% and epi 1.6%, P = 0.669) were also observed. Apparent transmural migration of rotational activations (n=6) from the epi- to the endocardium was seen in 2 patients. EGM fractionation was significantly higher in the epicardium than endocardium (61.2% versus 51.6%, P < 0.0001). The authors concluded that simultaneous endo-epi phase mapping of prolonged human persistent AF recordings showed significant EED marked temporal heterogeneity, discordant and transitioning wavefronts patterns and complex fractionations. No sustained focal activity was observed. Such complex 3-dimensional interactions provide insights into why endocardial mapping alone may not fully characterize the AF mechanism and why endocardial ablation may not be sufficient. Paul J. Wang: In our next paper, Andrew Beaser and associates hypothesize that intravascular ultrasound [IVUS] could accurately visualize and quantify intravascular lead adherence and degree of intravascular lead adherence correlates with transvenous lead extraction difficulty. Serial imaging of leads occurred prior to transvenous lead extraction using IVUS. Intravascular lead adherence areas were classified as high or low grade. Degree of extraction difficulty was assessed using 2 metrics and correlated with intravascular lead adherence grade. Lead extraction difficulty was calculated for each patient and compared to IVUS findings. 158 vascular segments in 60 patients were analyzed: 141 (89%) low grade versus 17 (11%) high grade. Median extraction time (low = 0 versus high grade 97 seconds, P < 0.001) and median laser pulsations delivered (low = zero versus high grade 5,852, P < 0.001) were significantly higher in the high-grade segments. Most patients with low lead extraction difficulty score had low intravascular lead adherence grades. 86% of patients with high lead extraction difficulty score had low IVUS grade, and the degree of transvenous lead extraction difficulty was similar to patients with low IVUS grades and lead extraction difficulty scores. Paul J. Wang: In our next paper, András Bratincsák, and associates sought to create the foundation of normative ECG standards in the young using Z-scores. 102 ECG variables were collected from a retrospective cohort of 27,085 study subjects with no known heart conditions, age zero to 39 years. The cohort was divided into 16 age groups by gender. Median interquartile range and range were calculated for each variable adjusted to body surface area. Normative standards were developed for all 102 ECG variables, including heart rate; P, R, and T axis; R-T axis deviation; PR interval, QS duration, QT, and QTc interval; P, Q, R, S, and T amplitudes in 12 leads; as well as QRS and T wave integrals. Incremental Z-score values between negative 2.5 and 2.5 were calculated to establish the upper and lower limits of normal. Historical ECG interpretive concepts were reassessed and new concepts observed. The author summarized that electronically acquired ECG values based on the largest pediatric and young adult cohort ever compiled provide the first detailed, standardized, quantitative foundation of traditional and novel ECG variables. Paul J. Wang: In our next paper, Jungmin Hwang and associates hypothesize that suppressing the late sodium current may counterbalance the reduced repolarization reserve in long QT syndrome [LQTS] and prevent early depolarization [EAD] and polymorphic ventricular tachycardia [PVT]. They tested the effects of selective late sodium channel blocker GS967 on polymorphic ventricular tachycardia [PVT] induction in a transgenic rabbit model of type two using intact heart optical mapping, cellular electrophysiology, and confocal calcium imaging and computer modeling. They found that GS967 reduced ventricular fibrillation [VF] induction under a rapid pacing protocol (7 out of 14 hearts in control versus 1 out of 14 at 100 nanomolar) without altering action potential duration [APD] or restitution and dispersion. GS967 suppressed PVT incidents by reducing calcium mediated EADs and focal activity during isoproterenol perfusion (at 30 nanomolar, 7 out of 12 and a 100 nanomolar, 8 out of 12 without EADs and PVTs). Confocal calcium imaging of LQT myocytes revealed GS967 shortened calcium transient duration by accelerating sodium calcium exchanger mediated calcium efflux from cytosol, thereby reducing EADs. Computer modeling revealed the inward late sodium current potentiates EADs in the LQT setting through providing additional depolarizing currents through action potential plateau phase, and increasing intracellular sodium that decreases the depolarizing sodium calcium exchanger, thereby suppressing the action potential plateau and delaying the activation of slowly activating delayed rectifier current, IKS. Suggesting important roles in the late sodium current in regulating intracellular sodium. Thus, the authors concluded that selective late sodium channel blockade by GS967 prevents EADs and abolishes PVT in LQT rabbits by counterbalancing the reduced repolarization reserve and normalizing intracellular sodium. Paul J. Wang: In our next paper, Pietro Lazzerini, Mohamed Boutjdir and associates, hypothesize that systemic inflammation per se can significantly prolong QTc during infection via cytokine-mediated changes in potassium channel expression. They found in patients with acute infections, regardless of concomitant QT-prolonging anti-microbial therapy, QTc was significantly prolonged but rapidly normalized in parallel to C-reactive protein [CRP] and cytokine level reduction. Consistently, in Torsades de Pointes cohort, concomitant acute infections were prevalent 30% despite only a minority (25%) of these cases were treated with QT-prolonging anti-microbials. KCN J2, potassium channel expression in peripheral blood mononuclear cells was strongly correlated to that in ventricles, inversely associated to CRP and interleukin one changes in acute infection patients. The authors concluded that acute infection, systemic inflammation rapidly induces cytokine-mediated ventricular electrical remodeling and significant QTc prolongation, regardless of concomitant antimicrobial therapy. Paul J. Wang: In a research letter, Christophe Beyls and associates examined the risk of bradycardia and critically ill COVID-19 patients treated with Lopinavir [LPV], a protease inhibitor of HIV-1, and Ritonavir [RTV], another protease inhibitor that strongly inhibits hepatic cytochrome P 450 [CYP3A4] activity in order to increase the Lopinavir plasma concentration. During the first month of the outbreak, patients admitted to the ICU with positive PCR for COVID-19 received LPV (200 mg)/RVT (50 mg) twice daily for 10 days. Bradycardia was defined as heart rate below 60 for a period of more than 24 hours. All patients were monitored 24 hours a day for all hemodynamic parameters, including heart rate with a five-lead ECG. Monitors were linked to a computerized system allowing to extract hemodynamic data. LPV/RTV plasma concentration was monitored using analytic method, combining high propensity performance, liquid chromatography and tandem mass spectrometry at 72 hours and every 72 hours. They prospectively included 41 COVID-19 patients who received LPV/RTV treatment. Nine or 22% patients experienced bradycardia. No patients had a pre-existing nodal pathology on the ECG on admission. Among the 9 patients with bradycardia, 8 or 88% were sinus bradycardia and one (12%) third-degree AV block. Causality may be considered as bradycardia occurred at least 48 hours after LPV/RTV initiation, bradycardia resolved after discontinuation or dose reduction and no alternative cause was found. Patients who presented with bradycardia were older, had a higher RTV plasma concentration and a lower lymphocyte count. In our study, no correlation was found between RTV plasma concentration, LPV plasma concentration, and mean heart rate at day three. No patient had bradycardia in the first 48 hours after LPV/RTV administration. For patients with LPV RTV plasma level overdose, the dose of LPV RTV was divided by two until the next dose. For the patient with third degree AV block LPV/RTV was stopped. None of the patients had any known cytochrome CYP3A4-inhibiting drugs. The authors concluded that the results suggest that RTV plasma overdose in elderly critical ill patients may increase the risk of bradycardia. Paul J. Wang: In a research letter, Emily Zeitler and associates surveyed cardiac implantable device [CID] patients. A total of 109 patients were approached to participate, nine declined. Most respondents were white (79%), male (60%) with a mean age of 73 years. The median number of correct responses to the 11 factual questions was six. Respondents held some common misconceptions. For example, 25% of respondents believe that FDA determines the cost of the device. Trust in the FDA was high; 67% of respondents agreed "I trust the FDA". Respondents mostly agreed "the FDA would not approve my device unless it was a hundred percent safe". Only 6% of respondents agreed, "we would be better off if there was no FDA," and a similarly small fraction disagreed with "when it comes to medical devices, the U.S. does the best job in the world at keeping people safe". Most respondents, 69% demonstrated fear of device recalls by agreeing with "if there was a recall of all are part of my device, I think I would be worried or scared." On average, respondents were comfortable sacrificing some privacy for device surveillance, 75% agreed with "once the device has been approved, the FDA should continue to monitor for signs that there are problems with the device even if it means that private health information about me is collected". Respondents seemed to believe that the FDA was risk averse; 56% believed that the FDA does not approve devices unless they're a hundred percent safe. This is in contrast to trends shifting the demonstration of safety to post-approval settings and expanding acceptable forms of data for regulatory approval. Paul J. Wang: In a research letter, Laura Rottner, Christoph Sinning and associates examined novel high resolution imaging system based on a wide band dielectric technology, and reports the first clinical experience of feasibility and reliability of cryoballoon [CB] occlusion tool as compared to fluoroscopic and 3D transesophogeal [TEE] assessment during pulmonary vein isolation [PVI]. In consecutive patients with symptomatic atrial fibrillation [AF], cryoballoon-based ablation was performed with a novel 3D wide-band dielectric imaging system. Pulmonary vein [PV] occlusion was assessed with fluoroscopy in 3D-TEE and concomitantly correlated with the novel CB occlusion tool. The endpoint was defined as persistent PV isolation verified by spiral mapping catheter recordings 30 minutes after the last CB application. A total of 36 (90%) of PVs in 10 patients with paroxysmal (40%) and persistent (60%) were analyzed. In all patients, a normal PV anatomy with four separate PVs was documented. Visualization via 3D-TEE was feasible in 80% septal PVs and 100% of lateral PVs. In 67% of PVs, total PV occlusion was confirmed by all 3 imaging modalities. In 17% of PVs, incomplete PV occlusion was initially demonstrated by TEE and 3D dielectric imaging, whereas fluoroscopy suggested complete occlusion in initial analysis. After repositioning of the CB at 3 PVs, complete PV occlusion was verified by all three modalities. In 3 out of 36 (8%), no occlusion was initially seen by any imaging modality, for which the CB was repositioned resulting in total PV occlusion as confirmed by all three modalities. Two out of 36 PVs (6%) were confirmed to be occluded via fluoroscopy in 3D-TEE, but not by the CB occlusion tool. There was only one out of 36 PVs (3%), which were confirmed to be included by the CB tool and 3D-TEE, but not by fluoroscopy. A negative and positive predictive value of 1.0 and 0.6 was seen when comparing PV occlusion by the novel occlusion tool compared to PV collusion, verified by fluoroscopy and 3D-TEE. Paul J. Wang: In a special report, Jun Hirokami, and associates aim to clarify the spatial correlations between fractionated potential detected by Lumipoint with non-PV trigger. They enrolled 30 symptomatic atrial fibrillation [AF] patients who underwent non pulmonary vein [PV] foci ablation. 4 patients underwent the first procedure, 17 underwent second procedure and eight underwent third procedure, and one underwent a fourth procedure. They highlighted the fractionated signal area in atrial muscle [FAAM] during sinus rhythm and atrial pacing, thereby producing a digital FAAM map. They retrospectively applied Lumipoint to 30 patients in order to clarify the relationship between FAAM and non-pulmonary vein [PV] foci. Non-PV foci were successfully identified in all patients. They identified four patients with multiple non-PV foci. Of these four patients, one had non-PV foci at the superior vena cava and left arterial anterior wall. One had non-PV foci at the SVC and LA bottom wall. And two had non-PV foci at the SVC and interatrial septum. They only analyze 30 non-PV foci unrelated to SVC because the SVC isolation was routinely performed for non-PVC foci at the SVC. In order to analyze the correlation between FAAM and location of non-PV triggers, they determined the cutoff points of peaks slider, which non-PV triggers were completely located within the FAAM in. The accuracy of predicting location of the non-PV triggers was summarized using area under the receiver operating curve, a UROC curve. The optimal cutoff point of peak sliders to predict the location of non-PV was determined by the Youden Index. The Youden Index established the optimal cutoff point of the maximum peaks slider was 7; sensitivity was 0.906 and specificity 0.770. The peaks slider 7 was the most accurate predictor fractionated signals location area to the location of non-PV triggers. (area under the curve 0.902). The mean area of peaks slider 7 was six centimeters squared or 4.3% of the atrium. The authors concluded that the proof-of-concept observational study demonstrated that novel visualization tool of FAAM map successfully identified non-PV triggers that did not induce atrial fibrillation and/or non-PV foci, which potentially serve as substrates for AF maintenance. Paul J. Wang: In a special report, Leslie Saxon and associates update their prior publication providing further detail on mitigation adoption rates for the entirety of the U.S. patient population with implanted cardiac rhythm management devices falling under FDA cyber security advisories from any device manufacturer. They also provided limited data on known cybersecurity mitigation adoption outside the U.S. They report a unique complication resulting for introducing firmware to already implanted devices. Discuss how evolving FDA policies towards firmware mitigation adoption may increasingly determine how and when updates occur. They found that patients under 50 years of age and those over 80 years were less likely to receive the software upgrades, and male versus females had greater rates of upgrades. The upgrade rates varied according to U.S. Region and date of implant. Resynchronization devices were less likely to receive the upgrade, as were pacemaker dependent patient. Those ICD patients initially falling under the battery advisers were upgraded more frequently. The number of advisory patients followed in clinic was a significant predictor for firmware upgrade adoption, particularly for pacemakers that were often upgraded in smaller size clinics. Overall, only 24% of devices for all groups, and 22% of devices not impacted by the battery advisory were upgraded. For Abbott devices, the home communicator cyber security vulnerabilities were mitigated with an automatic software patch that was updated using the Merlin network, and adoption rates were nearly a hundred percent. For the entire patient cohort with impacted pacemaker and ICDs, U.S. and global adoption rates remain low at 24 to 35% with a low rate of complications. Most reported complications for pacemakers and ICD were symptoms (transient palpitations, dizziness, or syncope) that resulted from the temporary change in mode to VVI or transient loss of programmer telemetry while performing the upgrade (pacemaker 0.05%; ICD 0.01%). Globally, a total of 9 pacemakers and 8 ICDs required replacement, as a result of performing the firmware upgrade due to irreversible reversion to a backup pacing mode and loss of defibrillation therapy (ICDs). Analysis of the returned ICD pulse generaotrs found at 7 cases, the cause related to a capacitor bond failure that was exposed only when extended telemetry as required by the upgrade. The failure mechanism was an isolated component failure in the remaining ICD. The programmer based test has recently been FDA approved and can be performed prior to firmware upgrade to identify ICD patients at risk for capacitor bond failure. A total of 256 ICDs were susceptible to loss of RF telemetry after receiving a firmware update, and this has since been mitigated with a software patch. For Medtronic programmers, the initial mitigation responses of cybersecurity advisory was to take the programmers off the network. The network connection was enhanced with one or more security protections provided to the programmers using a flash drive, so the programmers can now be secured from potential cyber intrusion when connected to the network. Medtronic ICDs are currently being upgraded. The upgrade is being provided to impacted patients automatically when the device is interrogated with the programmer during follow-up. Metronic is introducing upgrades in phased approach with all expected to be completed by the beginning of 2021. There are 9% or 55,000 ICDs under this advisory that cannot receive the update due to design or safety constraints. Since the 2017 Abbott advisories identify cybersecurity vulnerabilities in pacemakers and ICDs with the potential for exploits have been increased, including 2 additional FDA advisories issued for another manufacturer. Medtronic's connected communication product and implantable defibrillators in the past 12 months. The authors comment that a recent report and a smaller number of Abbott impacted pacemaker and ICD patients from Canada reported marked differences in mitigation adoption rates between pacemakers and ICDs. This was due to an increase incremental clinical familiarity and comfort with performing the updates as experience and education surrounding these issues evolve. The authors indicate that automating cybersecurity updates without process in place for determining safety, for alerting patients or clinicians that have been delivered, may also be associated with yet unknown risks. Newer generation devices and communication protocols may render cyber security, advisories less frequent as cybersecurity integration is considered an essential aspect of device design. Paul J. Wang: In a review article, Albert Feeny and associates discuss the use of artificial intelligence [AI] and machine learning [ML] in medicine, which are currently areas of intense exploration showing potential to automate human tasks or even perform tasks beyond human capabilities. The first objective of this review is to provide the novice reader with a literacy of AI/ML methods, and to provide a foundation of how one may conduct an ML study. The review provides a technical overview of some of the most commonly used terms, challenges in AI/ML studies with reference to recent studies in cardiac electrophysiology to illustrate key points. The second objective of this review is to use examples from the recent literature to discuss how AI and ML are changing clinical practice and research in cardiac electrophysiology with emphasis on disease detection and diagnosis, prediction, and patient outcomes and novel characterization of disease. The final objective is to highlight important considerations and challenges for appropriate variation, adoption, and deployment of AI technologies and practice. Paul J. Wang: That's it for this month! We hope that you will find the journal to be the go-to place for everyone interested in the field! See you next time! This program is copyright American Heart Association 2020. Thank you.  

Sandra Shaw is a regular performer with some of Canberra’s best ukulele groups.  She plays a bit of flute as well!  I took a picture of her very pretty travel ukulele. In our chat, Sandra mentioned some regular URoC performances: Floriade Canberra National Multicultural Festival National Folk Festival Blue Mountains Ukulele Festival Groups Sandra plays with are: The Ukulele Republic of Canberra (URoC) Loud in the Library Wattas Go to the Ukulele Is The New Black YouTube channel for a playlist with all the songs mentioned in this episode. And don’t miss the Gang Gang Twang festival on 4th April 2019 in Canberra.  Sandra and I will be there! Songs played in this episode are: All About That Uke: lyrics by Mike Hayllor (aka Krabbers), a parody of All About That Bass by Meghan Trainor and Kevin Kadish Dragonfly: by A.J. Leonard Lost on You: written by LP, Michael Gonzales, Nate Campany and Erick Landero. Performed by Amber Shuhyta (vocals), Meredith Harper (vocals and percussion), Jasmine Fellows (cello), Sandra Shaw (flute), Jim Croft (ukulele) and Emma (vocals and ukulele). The music played in this episode is licenced under a Podcasts (Featured Music) agreement with APRA AMCOS.

Henry Howard joins me in studio to talk all things Road and Trail Ultrarunning, Health, Food, Coaching, and being an Ambassador. You can find Henry at https://www.runspirited.com/ IG: @run_spirited Twitter: @runspirited Facebook: @Runspirited Coaching Info: http://www.ryanclaytoncoaching.com Inside Tracker: https://www.insidetracker.com/ Thanks for listening! The best way to get a hold of me is on Twitter: https://twitter.com/runrunrc Say Hi!! My KIT http://geni.us/RyanClaytonKit YouTube https://www.youtube.com/c/RyanClaytonFilms Instagram https://www.instagram.com/ryanclayton Twitter https://twitter.com/runrunrc Facebook https://www.facebook.com/ryanclaytoncoaching

Today’s episode is with Andrew Rankine, a fellow member of the Ukulele Republic of Canberra.  This was recorded after URoC’s performance at the 2018 Shoalhaven Heads Ukulele Festival. Go to our YouTube channel for songs and artists mentioned in the episode.  If you want to listen to Andrew’s favourite radio station it’s QBN FM.  Also a shout-out to the Wattas for their rendition of Pachelbel’s Canon Want to support the podcast?  Donate or buy merch on our website, ukuleleisthenewblack.com. The music played in this episode is licenced under a Podcasts (Featured Music) agreement with APRA AMCOS.

I review UROC, the Ultra Race of Champions. Including an interview with finisher Ashley Blake. Click to Download RSS Feed You can also watch the YouTube version of the podcast! Same exact content, just put on YouTube for those who don't do podcasts. See the pictures while I talk. UROC Forever Trails water bottle I mentioned. With Ashley at the finish My run in Charleston West Virginia. Thomas "Stonewall" Jackson Union soldier Lincoln University of Charleston Course maps Shirt. SFuels. Medal. Packet pickup. Motel at Camp Blue Ridge. Race morning: Francesca Conte Anthony Kunkel Amanda Basham Michael Wardian First part of race Blue Ridge Parkway Whetstone Ridge Trail Back near 100K/50K split, around mile 32. That's the finish up there, but we won't approach it from here in the end. Going right past the eventual finish, around mile 34. Just past the finish, heading out with 30 miles to go. Up to Bald Mtn aid station. Sections of second part of course. More rocks. Ashley and Tim. Done! With RD James Gill.

This Hotwire we bring you an interview with an anarchist in Managua about the past few weeks of anti-government revolt in Nicaragua. We also report on the arrests of anti-fascists in Georgia, a school bus drivers' strike also in Georgia, a hunger strike in San Diego's jails, and community resistance to ICE raids in North Carolina. Next week we'll bring you our regular episode a day late, but look out for a May Day special we're releasing to tide you over—and don't forget to e-mail us your May Day action reports at podcast@crimethinc.com! {April 25, 2018}   -------SHOW NOTES------   Table of Contents: Introduction {0:00} Headlines {1:30} Interview: A Week of Revolt in Nicaragua {16:40} Repression Roundup {27:10} Next Week's News {32:55} Download 29:30 minutes long version Events this weekend: April 26–29: The Southeast Trans and/or Women Action Camp in the smoky mountains of western North Carolina. Find out more by e-mailing setwac@protonmail.com.   April 26–28: the Anarchist Black Cross solidarity festival at EKH in Vienna, Austria. April 28–29: The Revolutionary Organizing Against Racism Conference (ROAR) returns to Ohlone land, the so-called Bay Area, California, in both Oakland and San Francisco. April 29: MACC in NYC is hosting a pre-May Day gathering in Tompkins Square Park at 1 PM. MAY DAY! In Montreal, anarchists will gather at 6 PM on the corner of Amherst and Sherbrooke. New York City: anarchist contingent in the big May Day march. Durham, NC: autonomous actions and a march starting at the old Durham Police headquarters at 6 PM. Seattle, WA: decentralized, autonomous actions Olympia. WA: decentralized, autonomous actions Portland, OR: coordinated, decentralized actions Eugene, OR: a really free market at the First Christian Church on Oak Street. Los Angeles, CA: a disruptive march Make sure to e-mail your May Day action reports to podcast@CrimethInc.com by May 2 so we can include them in our May Day roundup. Fundraising: Donate to the anti-fascists arrested in Newnan, Georgia on Saturday while protesting against neo-Nazis. Donate to the legal support fund for the four people charged over last year's May Day actions in Olympia. Other podcasts mentioned on this Hotwire: Unicorn Riot and End of the Line podcast are keeping people up to date as the struggle against the Mountain Valley Pipeline unfolds. We sample Alanis' aetheistic rant from The Ex-Worker Holiday Special before we lambast The Church of Satan. Hotwire 19 describes the anti-ICE organizing going on in Koreatown, Los Angeles. Episode 50 of The Ex-Worker has an interview with about the Lucasville prison uprising and how it informs contemporary prison rebellion and organizing We sampled the 99% Invisible episode “Church (Sanctuary, Part 1)” when discussing the sanctuary movement of the 1980s. Part 2 is also great. Get inspired to do something AWESOME for May Day by listening to the very first episode of The Ex-Worker, which is all about Haymarket. Anarchist texts related to this Hotwire: From Confronting Fascists to Facing the Police State: Reflections on the Anti-Fascist Mobilization in Newnan, Georgia God and the State by Mikhail Bakunin June 11: The History of a Day of Anarchist Prisoner Solidarity The May Days: Snapshots from the History of May Day Start gearing up for a summer of anarchy in Quebec! The anarchist film festival (May 17–20 in Montreal) The Montreal International Anarchist Theatre Festival (May 22–23 in Montreal) The Montreal Anarchist Bookfair (May 26–27 in Montreal) The North American Anarchist Studies Network Conference (June 1–3 in Montreal) Anti-G7 mobilization (June 7–9 in Quebec City) Mutual Aid Disaster Relief tour April 25, 26, and 27 at 5:00 PM at Youth Initiative High School 500 East Jefferson St Viroqua, WI 54665 April 28 at 5:30 PM at Menomonie Market Food Co-op 814 Main Street E Menomonie, WI 54751 April 29 at 10:00 AM at Family & Learning Center 523 Cedar Ave. E. Menomonie, WI 54751 May 2 at 6:00 PM at Walker Community Church 3104 16th Ave S Minneapolis, MN 55407 May 3 at 6:00 PM at UROC 2001 Plymouth Avenue North Minneapolis, MN 55411 Use this straightforward guide to writing prisoners from New York City Anarchist Black Cross to write birthday greetings to political prisoner Janine Phillips Africa. Janine Phillips Africa #006309 SCI Cambridge Springs 451 Fullerton Avenue Cambridge Springs, Pennsylvania 16403 {Birthday: April 25} Also, please write a letter to Cedar, a comrade in Ontario who is in jail over conspiracy charges stemming from the March 5 anti-gentrification march in Hamilton, Ontario. Please address the envelope to Peter Hopperton and the letters to Cedar: Peter Hopperton Hamilton-Wentworth Detention Centre 165 Barton St East Hamilton ON L8L 2W6 Phone zaps: Call the warden of Central Ohio Correctional Facility at 330–743–0700 and use this script: “Hello, my name is _____. I'm calling to demand you reverse Friday's policy changes that imposed new restrictions on prisoners impacted by the Lucasville uprising. None of these prisoners violated any rules and there's no justification for rolling back important policies that help them survive the 25 years of solitary confinement the ODRC has cruelly subjected them to.” Support the 200+ hunger strikers in Santa Clara County Jails by calling the Sheriff Administration at 408–808–4900 or the Board of Supervisors at 408–299–5001 and demanding that they enter into negotiations with the hunger strikers. Call DeKalb County, GA School Superintendent Stephen Green at 678–676–1200 to demand immediate reinstatement, with no pay lost, of all fired drivers. You can use this script: “Hello, my name is ________. I would like to let you know that I support the school bus drivers. I think it is shameful that the immediate reaction in response to the sick- out was to fire drivers, rather than to negotiate with them. The drivers have a right to organize without fear of retaliation, including by withdrawing their labor. I support their efforts to improve their jobs, and demand that the district immediately reinstate all fired drivers, with no pay lost and no other kind of discipline. None of the drivers who participated should be retaliated against. I also demand that the district immediately recognize the drivers committee and begin negotiating with them. Will you agree to rehire the drivers and recognize their committee?” Call the City of Olympia prosecutor's office at 360–753–8449 to demand they drop the charges against the four May Day defendants. J20 support resources: POSTER: The J20 Prosecution—Trumped up Charges J20 Legal Defense Fund Twitter Fed book An Open Letter to Former J20 Defendants, with useful “do”s and “don't”s  Teen Vogue: The J20 Arrests and Trials, Explained Tell the prosecutor's boss to drop the charges by calling (202) 252–7566  

L-R: Rockin the track with some new Altra Escalantes; Broken Arrow Sky Race; Vegan Power!; Racing TNF San Fran; 2nd place (11:54) at UROC 100k 2017 Laura Kline is a multi-sport athlete visiting by way of Syracuse, NY. During our conversation, we talk a bit about traveling the world, racing at the front, having nobody to punch, gaining confidence and finding the line between competing as hard as possible while trying not to destroy yourself. From World Championship Triathlons and now to ultras, Laura has traveled around the country and the world racing at a very high level.Laura runs for Altra Footwear and is part of the MPF / RNR racing team, as well as frequently running as a member of Strong Hearts Vegan Power.  Episode LinksLaura on TwitterWe talked for an hour but we barely scratched the surface of Laura's extensive race historyBroken Arrow SkyRaceJason's Western States experience on Must Love JogsMintz On Running Inside OutTNF San FranciscoAltra Footwear 0 SPFTNF Ontario On the podium at The North Face Ontario 50 mile Strong Hearts Vegan PowerMountain Peak Fitness / Red Newt RacingRunners (mentioned) Jason Mintz Mike Welden Ian Golden Mark Monachino Sarah Keyes Kip Tisia Eric Eagan(mentioned) Special Guest: Laura Kline.

This should be a blast! We are joined by the kick-ass, Chris Mocko, to chat about his recent win at UROC, training for Western States 100 and more!

UROC 100k race report!  Honored to be an ambassador to this awesome event for the third year running!  Really love it's new home in the Blue Ridge Mountains!  Hope to see you there next year! http://victorysportdesign.com/ http://drymaxsports.com/ http://ultrarunningcompany.com/ https://sundogeyewear.com/ http://paradigmwellnessmed.com/ http://os1st.com/ http://www.biotropiclabs.com/ And https://guenergy.com/   All Day!

I ran the Grayson Highlands 50K in Virginia and talk about it and interview others who ran it. Also, my 50 mile weekend, the YMCA, and Five Chinese Brothers. Click to Download Listen to this episode on YouTube! Same content, just for those who don't do podcasts. Please donate to keep this show going! THANK YOU! This episode brought to you by: Spoken Bicycles of Middletown Ohio. Spoken Bicycles is a new bicycle shop in downtown Middletown that also features a craft beer taproom. They offer new road, hybrid and city bikes. They service all bikes, and have gear and accessories you can't find anywhere else in the Midwest. They also have group rides and runs that leave from the shop. Visit their website at www.spokenbicycles.com for more information about their store! I gave the WRONG TWITTER HANDLE: It's @RunSmithE (not @RunSmith) Donate to Shawn Bearden's 777 Marathon Challenge at the Science of Ultra. Do it in May and he'll match your donation! Grayson Highlands 50K I mentioned the Frozen Sasquatch Race. Some pics from when I did it in 2016: I mentioned UROC. And the Highlands Sky Trail Run. Barney mentioned the Barkley Fall Classic, ARFTA, and RUTS. Julie and Sandy (whom I interviewed) And Barney Pictures from the Grayson Highlands Race: Elevation chart: We crossed the Appalachian Trail many times: With race direction Sean "Run Bum" Blanton The Five Chinese Brothers

Diablo 50k race report!!  Make sure to get you predictions in for my upcoming UROC 100k finish time!  You could win some awesome gear from OS1st bracing, including the calf sleeves I love and a sweet trucker hat! Running Stupid is brought to you by: http://victorysportdesign.com/ http://drymaxsports.com/ http://ultrarunningcompany.com/ http://sundogeyewear.com/ http://paradigmwellnessmed.com/ http://os1st.com/ http://www.biotropiclabs.com/  And big thank you to: http://guenergy.com/ All Day!

UROC 100k DNF Report! http://ultraroc.com/ Running Stupid is brought to you by: http://victorysportdesign.com/ http://drymaxsports.com/ http://ultrarunningcompany.com/ http://sundogeyewear.com/ http://paradigmwellnessmed.com/ http://os1st.com/ And big thank you to: http://guenergy.com/   All Day!

I am joined by the incredible Magdalena Boulet to talk all about her stellar 2015 season where she hasn't finished below first place in every race she's ran. This one is going to be great!

The Ultra Race of Champions, UROC, is being held in Auburn, CA tomorrow.  This nomatic race is very unique.  We visit with race directors, Francesca Conte and James Gill, to find out more about this race and what they are creating. For other races by Francesca and James, visit Bad to the Bone Click here to register

Join me and Chris Vargo as we chat about his upcoming race, The Ultra Race Of Champions! It’s an epic race, with an even more epic line-up of runners. And we finally get another Just The Tip w/ Chris Vargo! For the full review, be sure to visit: http://GingerRunner.com For...

In two years, she will have been hit by a car, pulled a calf, been coached and coached others, won Speedgoat, placed at UROC,  trained for States, earned her Ph.D, and gotten married.  Wow! Listen as I pick Stephanie’s brain about training, nutrition, injury, coaching, and what the heck happened … The post Stephanie Howe Interview appeared first on Ultrarunnerpodcast.com.

We have an interview with Speedgoat 50k winner and 2nd place at UROC, Stephanie Howe. Brit fell running sensation, Ricky Lightfoot talks about his progression to ultra. Anthony Bethell provides an insight into his first year participating in the Skyrunning season from an everyday runners perspective. Marc Talks Training. Emelie Smiles and Miles. The news, a blog, up and coming races and Speedgoat is back!

Mountain running legend, Jono Wyatt tells us all about his incredible 25 years as a competetive athlete. We speak to man of the moment, Rob Krar after his impressive win at UROC. Emelie Forberg is back with Smiles and Miles. Marc Laithwaite talks altitude in Talk Training. The News, a Blog, Up and Coming Races and Stevie Kremer co-hosts the show.

Nu er det DIN tur til at komme i Trailcast! Er du trailløber og har du en interessant historie, som måske kan inspirere andre, så skriv til mig og fortæl lidt om, hvem du er. Adressen er redaktion@trailcast.dk. Du kan også høre om en ny podcast om ultraløb, og sidst i programmet tager jeg dig med til en hæsblæsende Salomon Trail Tour-finale i Rude Skov. Først skal du høre om Tracy Høeg, som efter et år hvor hun har givet den alt, hvad hun kunne, også må indse, at der er vigtigere ting end løb i verden. Lyden på det sidste indslag er ind i mellem ret dårlig og hvis du har problemer med at blive stønnet i øret, så skal du måske bare spole frem til denne episodes musikindslag, som er Stray Dogg med "Time (Feat. Devendra Bandhart).

We speak to man of the moment Max King after his incredible wins at UROC and JFK50. Oz fast man, Brendan Davies talks about the ultra scene down under and his win at GNW100. Pocket Rocket Stevie Kremer tells us what it's like to move from the US to Italy and race at the highest level. Talk Training is about run shoes. We have the news, a blog, up and coming races and of course Speedgoat Karl Meltzer.

Mike Wardian, ULTRArunnerThe Power Bar, Marathonguide.com & North Face Endurance Team’s Michael Wardian joins us just days after his second place finish at UROC. Michael had the lead with 7-8 miles to go and then he took a wrong turn. Hear what happened, what his thoughts were and how he … The post Mike Wardian, ULTRArunner appeared first on Ultrarunnerpodcast.com.