POPULARITY
Categories
The Koh-i-Noor is perhaps the world's most controversial diamond.
Tim Stracke, Gründer von Chrono24, und sein Bruder Philipp Stracke, Markenexperte, geben dir Einblicke in den strategischen Aufbau einer globalen Marke. Mit mehr als 60 Milliarden Euro Marktvolumen teilen die beiden, wie sie Chrono24 zur weltweit führenden Plattform für Luxusuhren entwickelt haben, warum Markenführung Chefsache ist und wie man eine nachhaltige Markenstrategie entwickelt. Was du lernst: Markenname & Positionierung: Warum sie bei "Chrono24" geblieben sind Die Balance zwischen deskriptiven und emotionalen Markennamen Wie man internationale Markennamen entwickelt Markenstrategie entwickeln: Die drei Säulen erfolgreicher Markenentwicklung Wann du externe Hilfe brauchst Warum Markenführung Chefsache ist Internationalisierung: Herausforderungen bei mehrsprachiger Kommunikation Lokale vs. globale Markenführung Kulturelle Unterschiede in der Markenwahrnehmung Prominente Investoren & Markenbotschafter: Der Cristiano Ronaldo Deal Unterschied zwischen Investor und Markenbotschafter Messung von Markeneffekten Do's & Don'ts: Warum Marke mehr als Marketing ist Die Bedeutung von Kohärenz Wie du nachhaltige Marken aufbaust ALLES ZU UNICORN BAKERY: https://zez.am/unicornbakery Mehr zu Philipp und Tim: LinkedIn: https://www.linkedin.com/in/timstracke/ , https://www.linkedin.com/in/philipp-stracke/ Website: https://www.chrono24.de/ Join our Founder Tactics Newsletter: 2x die Woche bekommst du die Taktiken der besten Gründer der Welt direkt ins Postfach: https://www.tactics.unicornbakery.de/ Kapitel: (00:00:00) Die Bewertung von Chrono24 (00:08:31) Was macht einen guten Markennamen? (00:14:17) How to: Marke aufladen (00:18:37) Markenkern festigen bei Chrono24 (00:32:55) Wie wichtig ist die Darstellung der Marke? (00:42:35) Ist es problematisch, eine Marke länderspezifisch zu denken? (00:50:48) Was hat alles Einfluss auf die Wahrnehmung der Marke durch den Endkunden? (00:58:37) Dos & Dont's Markenaufbau (01:04:17) Auswirkungen des Cristiano Ronaldo Deals (01:12:11) Markenbotschafter: Clever oder Risiko?
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Croesus, the king of Lydia, who reigned for 14 years in the 6th century BCE, was legendary for his wealth. You might wonder what the man did to protect his treasures. Well, rumor has it that he used to put curses on his most valuable belongings, including the infamous King Croesus's golden brooch, one of the most precious items in his jewelry collection. For hundreds of years, the treasure of King Croesus lay underground, lost but not forgotten. But one day in 1965, several men came across the ancient burial mound of a Lydian princess. The men didn't excavate all the treasure at once. They returned once again in 1968 but didn't find anything but wall paintings. Among the artifacts they'd stolen, there was a beautiful golden brooch in the shape of a winged seahorse... Other videos you might like: The Story of the Hope Diamond Which Ruined Its Owners' Lives • The Story of the Hope Diamond Which R... 4 Mystery Doors That Should Never Be Opened • 4 Mystery Doors That Should Never Be ... The Truth About the Titanic Has Been Revealed • The Truth About the Titanic Has Been ... TIMESTAMPS: Terrible things that happened to the thieves 1:30 Why the treasure had to be returned to Turkey 2:53 Where the real brooch?! 3:41 Other jewelry items that destroyed its owners: Black Orlov Diamond 4:31 Koh-i-Noor Diamond 5:24 Delhi Purple Sapphire 6:31 The Star of India 7:55 #cursedthings #legends #brightdise Star of Asia Sapphire 330 carats Burma Rumored to have once belonged to India's Maharajah of Jodhpur: By thisisbossi from Washington, DC, USA - 2009 04 19 - 4697 - Washington DC - Natural History Museum - Star of Asia Sapphire Uploaded by PDTillman, CC BY-SA 2.0 https://creativecommons.org/licenses/..., https://commons.wikimedia.org/w/index... Animation is created by Bright Side. Music by Epidemic Sound https://www.epidemicsound.com/ Subscribe to Bright Side : https://goo.gl/rQTJZz ---------------------------------------------------------------------------------------- Our Social Media: Facebook: / brightside Instagram: / brightgram 5-Minute Crafts Youtube: https://www.goo.gl/8JVmuC Stock materials (photos, footages and other): https://www.depositphotos.com https://www.shutterstock.com https://www.eastnews.ru ---------------------------------------------------------------------------------------- For more videos and articles visit: http://www.brightside.me/ Learn more about your ad choices. Visit megaphone.fm/adchoices
Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPSES conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control. Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPS conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control. Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
Podcast Summary This episode of the Pain Exam Podcast, hosted by Dr. David Rosenblum, discusses an interesting article about Ketorolac injections for musculoskeletal conditions. The podcast covers: Ketorolac is an NSAID that provides analgesic and anti-inflammatory effects through inhibition of prostaglandin synthesis Multiple studies comparing Ketorolac injections to corticosteroids and hyaluronic acid for various conditions Research shows Ketorolac injections are equally effective as corticosteroids for subacromial conditions, adhesive capsulitis, carpal-metacarpal joint issues, and hip/knee osteoarthritis Ketorolac may be a safer alternative to steroids for certain patients, though it has its own contraindications for those with renal, gastrointestinal, or cardiovascular disease Dr. Rosenblum considers the potential of using Ketorolac injections directly at pain sites rather than intramuscularly Upcoming Courses and Conferences Ultrasound courses in New York and Costa Rica (check unwrappedpain.org) Private ultrasound sessions available Dr. Rosenblum will be speaking at Pain Week about ultrasound in pain practice and PRP Presenting at a primary care conference in London Teaching ultrasound at ISPN LAPSES conference in Chile (Dr. Rosenblum won't attend this year) Ketorolac Injections: An Effective Alternative for Musculoskeletal Pain Management Musculoskeletal conditions such as bursitis, adhesive capsulitis, and osteoarthritis affect millions and often require injectable therapies to reduce pain and inflammation. Traditionally, corticosteroid injections have been the mainstay treatment. However, concerns over side effects like tendon rupture, cartilage damage, and systemic hyperglycemia have prompted exploration of alternatives. A recent narrative review by Kiel et al. (2024) highlights ketorolac—a parenteral nonsteroidal anti-inflammatory drug (NSAID)—as a promising substitute for corticosteroids in musculoskeletal injections. Warning: OFF Label use of Ketorolac discussed. Please consult your physician. See full article for details. Subacromial Ketorolac Injections for Shoulder Pain Subacromial bursitis and impingement syndrome are common causes of shoulder pain and disability. Several randomized controlled trials have shown that subacromial ketorolac injections provide pain relief and functional improvement comparable to corticosteroids: Goyal et al. demonstrated significant reductions in pain scores after subacromial injection of 60 mg ketorolac versus 40 mg methylprednisolone, with no difference in outcomes between groups. Taheri et al. found similar short-term pain relief at 1 and 3 months with either ketorolac or corticosteroid subacromial injections. Kim et al. reported equivalent clinical improvement in rotator cuff syndrome patients receiving ketorolac or triamcinolone injections. Min et al. noted ketorolac led to better forward flexion and patient satisfaction at 4 weeks compared to corticosteroids. These studies support ketorolac as an effective agent for subacromial injection, offering an alternative for patients where corticosteroid use is limited. Intra-articular Ketorolac Injections for Adhesive Capsulitis and Osteoarthritis Adhesive capsulitis (frozen shoulder) and osteoarthritis of the hip, knee, and carpometacarpal joint are often treated with intra-articular corticosteroids. Ketorolac injections have shown comparable efficacy in these conditions: Akhtar et al. found intra-articular ketorolac significantly reduced shoulder pain at 4 weeks in adhesive capsulitis compared to hyaluronic acid. Ahn et al. reported similar pain relief between intra-articular ketorolac and corticosteroid injections in adhesive capsulitis, with ketorolac providing superior shoulder mobility at 3 and 6 months. Koh et al. showed that adding ketorolac to hyaluronic acid injections in carpometacarpal osteoarthritis resulted in faster onset of pain relief compared to hyaluronic acid alone. Park et al. observed equivalent functional improvements with intra-articular ketorolac or corticosteroids in hip osteoarthritis. Jurgensmeier et al. demonstrated similar symptom improvement at 1 and 3 months post-injection for ketorolac and triamcinolone in hip and knee osteoarthritis. Xu et al. and Bellamy et al. confirmed ketorolac's comparable pain relief and functional benefits to corticosteroids for knee osteoarthritis, with ketorolac being more cost-effective. Lee et al. noted quicker pain reduction with intra-articular ketorolac combined with hyaluronic acid versus hyaluronic acid alone in knee osteoarthritis. aSafety and Pharmacologic Considerations Ketorolac's anti-inflammatory action stems from cyclooxygenase inhibition, reducing prostaglandin synthesis. Its half-life is approximately 5.2–5.6 hours, and it is metabolized in the liver. Unlike corticosteroids, ketorolac avoids systemic hyperglycemia and cartilage damage risks. Animal and in vitro studies suggest ketorolac may protect cartilage by inhibiting inflammatory cytokines. While gastrointestinal, renal, and cardiovascular risks associated with NSAIDs remain considerations, localized intra-articular and subacromial ketorolac injections may limit systemic exposure and adverse effects. Mild, transient post-injection pain has been reported but resolves without intervention. Conclusion Ketorolac injections, administered intra-articularly or subacromially, are a safe, effective, and economical alternative to corticosteroids for managing common musculoskeletal conditions. Their comparable efficacy in reducing pain and improving function, combined with a more favorable side effect profile, makes ketorolac an appealing option for clinicians and patients alike. Further research is warranted to fully elucidate long-term safety and optimal dosing strategies. FAQS Ketorolac Injections for Musculoskeletal Conditions: Frequently Asked Questions Musculoskeletal pain from conditions like bursitis, adhesive capsulitis, and osteoarthritis often requires injectable treatments. Ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), is emerging as a promising alternative to corticosteroids. Below are common questions and answers based on a recent narrative review by Kiel et al. (2024). 1. What is ketorolac and how does it work? Ketorolac is a parenteral NSAID that reduces pain and inflammation by inhibiting cyclooxygenase enzymes, which decreases prostaglandin synthesis. It can be administered orally, intramuscularly, intravenously, or by injection directly into joints or around bursae. 2. How effective is ketorolac for musculoskeletal conditions? Studies show ketorolac injections provide significant pain relief and functional improvement comparable to corticosteroids in conditions like: Subacromial bursitis and shoulder impingement (subacromial injections) Adhesive capsulitis (frozen shoulder) (intra-articular injections) Osteoarthritis of the hip, knee, and thumb carpometacarpal joint (intra-articular injections) 3. What evidence supports subacromial ketorolac injections? Randomized controlled trials found: Goyal et al. and Taheri et al. reported similar pain reduction and functional outcomes between ketorolac and corticosteroids for subacromial injections. Kim et al. and Min et al. observed comparable or better patient satisfaction and shoulder mobility with ketorolac versus corticosteroids. 4. How does intra-articular ketorolac compare to corticosteroids for adhesive capsulitis? Akhtar et al. showed ketorolac reduced shoulder pain more than hyaluronic acid. Ahn et al. found ketorolac and corticosteroids equally effective for pain relief, with ketorolac providing better shoulder mobility at 3 and 6 months. 5. What about ketorolac for osteoarthritis? Ketorolac combined with hyaluronic acid provided faster pain relief than hyaluronic acid alone in thumb carpometacarpal joint osteoarthritis (Koh et al.). Intra-articular ketorolac had similar efficacy to corticosteroids in hip (Park et al., Jurgensmeier et al.) and knee osteoarthritis (Bellamy et al., Xu et al.). Ketorolac injections were more cost-effective compared to corticosteroids (Bellamy et al.). 6. Are ketorolac injections safe? Ketorolac's side effects are similar to other NSAIDs, mainly involving gastrointestinal, renal, and cardiovascular risks. However, localized intra-articular and subacromial injections may reduce systemic exposure. Animal studies suggest ketorolac does not harm cartilage and may protect against inflammatory damage. Mild, transient local pain post-injection is possible but usually resolves without treatment. 7. What are the limitations of ketorolac use? Ketorolac is not suitable for patients with: Renal impairment Gastrointestinal ulcers or bleeding risk Cardiovascular disease or hypertension NSAID hypersensitivity, especially in asthma or chronic urticaria patients Clinicians should assess individual risks before choosing ketorolac injections. 8. How does ketorolac's pharmacokinetics affect its use? Ketorolac has a plasma half-life of about 5.2 to 5.6 hours and is metabolized in the liver. Pharmacokinetics for subcutaneous or intra-articular administration are less defined but systemic absorption occurs. Its relatively short half-life supports repeated dosing if needed. 9. Why consider ketorolac over corticosteroids? Ketorolac avoids corticosteroid-associated risks such as tendon rupture, cartilage damage, and steroid-induced hyperglycemia. It is also more cost-effective, making it a favorable option for patients and healthcare systems. 10. What further research is needed? More large-scale, long-term studies are needed to fully understand ketorolac's intra-articular effects, optimal dosing, and safety profile compared to corticosteroids and other treatments. Summary: Ketorolac injections, whether intra-articular or subacromial, offer a safe, effective, and economical alternative to corticosteroids for managing various musculoskeletal conditions. This makes ketorolac an important option in pain management and inflammation control. Reference: Kiel J, Applewhite AI, Bertasi TGO, Bertasi RAO, Seemann LL, Costa LMC, Helmi H, Pujalte GGA. Ketorolac Injections for Musculoskeletal Conditions: A Narrative Review. Clinical Medicine & Research. 2024;22(1):19-27. DOI: https://doi.org/10.3121/cmr.2024.1847 Disclaimer: This Podcast, website and any content from NRAP Academy (PMRexam.com) otherwise known as Qbazaar.com, LLC is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user's own risk. Professionals should conduct their own fact finding, research, and due diligence to come to their own conclusions for treating patients. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
Koviubi és csíkos keksz gluténmentesen Kohári Évától a Kanapéban.
Some Christians in Malaysia—ethnically Chinese or Indian believers—have freedom to practice their faith in Christ. But if an ethnic Malay person becomes a believer in Jesus, he or she will face intense Christian persecution. The Malaysian government sees ethnic Malay people as off limits for evangelism and holds them subject to Islamic Shariah law. “To be Malay is to be Muslim,” says Carter Gates, leader of VOM's international ministry work in Asia/Pacific. “Ethnic Malay's can't even [openly] say they are interested in learning more about Jesus.” As Carter meets with VOM's ministry partners, one shared key hindrances that keep Malays from following Christ and the questions he uses as he engages them in gospel conversation. One of those questions: are you ready to die for Jesus? Gates says he was challenged as he thought about evangelism in free nations versus in Malaysia, Laos, Vietnam, China and other restricted areas and hostile nations. “This pastor is in a context where he knows what [sacrifice] means,” Carter says. “We should consider these costs in America too.” We'll also share an update on the court case over the forced disappearance of Pastor Raymond Koh in 2017. A verdict is expected in the case in November. Listen to what Susanna Koh shared during her first visit with VOM Radio about how she and her family struggled after her husband's abduction. She also shares how the Lord helped her to forgive those who persecuted her husband. Please pray for truth to be revealed through this legal process and pray for the Koh family as they await the verdict. The VOM App for your smartphone or tablet will help you pray daily for persecuted Christians—in Iran and other nations—throughout the year, as well as provide free access to e-books, audiobooks, video content and feature films. Download the VOM App for your iOS or Android device today.
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Achtzehnter Sonntag im Jahreskreis Lesung aus dem Buch Kohélet (Koh 1, 2; 2, 21–23) Psalm 90 Lesung aus dem Brief des Apostels Paulus an die Kolósser (Kol 3, 1–5.9–11) Aus dem heiligen Evangelium nach Lukas (Lk 12, 13–21) Erschaff mir ein reines Herz Sonntag, 3. August 2025 ________________________ Lesejahr: C I Sprecher: Marek Gierszał, Thomas Kycia Gesang: Anna Diouf (Psalm 90 & Halleluja); Dominikanerschola Ave Florum Flos (Erschaff mir ein reines Herz) Musik: Szymon Jakubowski; Jacek Sykulski & Traditional (Erschaff mir ein reines Herz) Jingle: Haroun Sweis Foto: P. Adam Rokosz OP Grafik: Danuta Mikeska-Kycia Projektbetreuung: Thomas Kycia Kontakt: info@bibeltogo.de Mehr auf: https://bibeltogo.de oder https://bibeltogo.podbean.com Instagram: https://www.instagram.com/bibel_to_go/ Facebook: https://www.facebook.com/BibeltogoPodcast Hat dir dieser Podcast gefallen? Bitte bewerte ihn und schreib uns einen Kommentar auf der Plattform, auf der du ihn gerade gehört hast oder schreib uns eine Mail an info@bibeltogo.de. Erzähle von diesem Podcast deiner Familie, Freunden und Verwandten! So werden noch mehr Menschen Gottes Wort hören können. _________________ Die biblischen Texte sind Bestandteil der von den Bischofskonferenzen des deutschen Sprachgebietes approbierten (revidierten) Einheitsübersetzung der Heiligen Schrift (1980/2016). Rechte: Ständige Kommission für die Herausgabe der gemeinsamen liturgischen Bücher im deutschen Sprachgebiet. Bibel to go. Die Lesungen des Tages Die Lesungen und das Tagesevangelium Das heutige Evangelium vorgelesen Evangelium Tag für Tag Bibel zum Hören Tageslesungen Bibel online Jahreskreis
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
In dieser Atemübung praktizieren wir die Kohärenzatmung und die Triangel Atmung. Beide Atemtechniken regulieren das Nervensystem bei regelmäßiger Praxis. Die Atemübung eignet sich bei Stress, Anspannung, Angststörungen und Mental Load. Durch die Atemübung wird das parasympathische Nervensystem stimuliert und der Vagusnerv wird aktiviert, wodurch der Körper in einen Zustand der Ruhe und Entspannung versetzt wird. Bei Bluthochdruck und in der Schwangerschaft wird empfohlen, keine Atempausen zu machen. Breathwork Ausbildung, Somatic Breathwork Coaching, körpertherapeutisches Coaching: www.geetaghosh.com Geeta auf Instagram: @geeta.ghosh.breathwork Atem-Coaching, Atemkurse, Kooperationen: hi@geetaghosh.com Medizinischer Disclaimer: Sämtliche im Podcast, auf meiner Website sowie auf meinen Social Media Profilen wie Instagram enthaltenen Informationen und Übungen stellen keinen Ersatz für eine professionelle ärztliche oder psychotherapeutische Beratung, Diagnose oder Behandlung dar. Die Inhalte des Podcasts sind nicht dazu bestimmt, Krankheiten zu diagnostizieren oder zu behandeln. Im Rahmen des Podcasts werden keinerlei medizinische oder gesundheitliche Heilversprechen oder Handlungsempfehlungen zu Medikation und Ähnlichem abgegeben. Alle Inhalte, einschließlich Atem- und Körperübungen, Literatur und sonstige Informationen in diesem Podcast und auf meinen übrigen Kanälen wurden mit größter Sorgfalt recherchiert und ausgewählt, erheben jedoch keinerlei Anspruch auf Vollständigkeit, Aktualität, Richtigkeit und Ausgewogenheit. Insbesondere sind sie in keiner Weise ein Ersatz für professionelle Diagnosen, Beratungen und Behandlungen durch ausgebildete und anerkannte Ärzt:innen, Heilpraktiker:innen und Psychotherapeut:innen. Ebensowenig dienen die Inhalte dieses Podcasts als Grundlage für eigenständige Diagnosen sowie Behandlungen oder Änderungen an einer durch Fachärzt:innen bereits empfohlene Behandlung und Medikation. Der Podcast dient ausschließlich der neutralen Information und allgemeinen Weiterbildung. Für die Vollständigkweit und Richtigkeit der Angaben sowie Schäden und Unannehmlichkeiten, die sich durch die Nichtbeachtung dieser Hinweise ergeben, wird - weder direkt noch indirekt - keine Haftung durch Geetashri Ghosh übernommen. Es wird empfohlen, alle Informationen von entsprechenden Fachärzt:innen überprüfen zu lassen.
In dieser Atemübung praktizieren wir die Kohärenzatmung und die Triangel Atmung. Beide Atemtechniken regulieren das Nervensystem bei regelmäßiger Praxis. Die Atemübung eignet sich bei Stress, Anspannung, Angststörungen und Mental Load. Durch die Atemübung wird das parasympathische Nervensystem stimuliert und der Vagusnerv wird aktiviert, wodurch der Körper in einen Zustand der Ruhe und Entspannung versetzt wird. Bei Bluthochdruck und in der Schwangerschaft wird empfohlen, keine Atempausen zu machen. Breathwork Ausbildung, Somatic Breathwork Coaching, körpertherapeutisches Coaching: www.geetaghosh.com Geeta auf Instagram: @geeta.ghosh.breathwork Atem-Coaching, Atemkurse, Kooperationen: hi@geetaghosh.com Medizinischer Disclaimer: Sämtliche im Podcast, auf meiner Website sowie auf meinen Social Media Profilen wie Instagram enthaltenen Informationen und Übungen stellen keinen Ersatz für eine professionelle ärztliche oder psychotherapeutische Beratung, Diagnose oder Behandlung dar. Die Inhalte des Podcasts sind nicht dazu bestimmt, Krankheiten zu diagnostizieren oder zu behandeln. Im Rahmen des Podcasts werden keinerlei medizinische oder gesundheitliche Heilversprechen oder Handlungsempfehlungen zu Medikation und Ähnlichem abgegeben. Alle Inhalte, einschließlich Atem- und Körperübungen, Literatur und sonstige Informationen in diesem Podcast und auf meinen übrigen Kanälen wurden mit größter Sorgfalt recherchiert und ausgewählt, erheben jedoch keinerlei Anspruch auf Vollständigkeit, Aktualität, Richtigkeit und Ausgewogenheit. Insbesondere sind sie in keiner Weise ein Ersatz für professionelle Diagnosen, Beratungen und Behandlungen durch ausgebildete und anerkannte Ärzt:innen, Heilpraktiker:innen und Psychotherapeut:innen. Ebensowenig dienen die Inhalte dieses Podcasts als Grundlage für eigenständige Diagnosen sowie Behandlungen oder Änderungen an einer durch Fachärzt:innen bereits empfohlene Behandlung und Medikation. Der Podcast dient ausschließlich der neutralen Information und allgemeinen Weiterbildung. Für die Vollständigkweit und Richtigkeit der Angaben sowie Schäden und Unannehmlichkeiten, die sich durch die Nichtbeachtung dieser Hinweise ergeben, wird - weder direkt noch indirekt - keine Haftung durch Geetashri Ghosh übernommen. Es wird empfohlen, alle Informationen von entsprechenden Fachärzt:innen überprüfen zu lassen.
The fog of uncertainty isn't a weakness in our religious experience—it's the proving ground of our most profound faith. Moses spoke to the tribal leaders with a unique clarity of prophecy, using the phrase "Zeh hadavar" (this is precisely what God said). But as Rashi teaches us, this perfect clarity was reserved only for Moshe. All other prophets received divine messages with some ambiguity, expressed as "Koh amar Hashem" (thus says the Lord). This distinction reveals a profound spiritual truth that transforms our understanding of faith itself.Rabbi Yosef Shlomo Kahaneman, the Ponevich Rav, found strength in this teaching after losing his family in the Holocaust. He pointed to Abraham's binding of Isaac as the ultimate example of faith, not because Abraham was willing to sacrifice his son, but because he proceeded despite overwhelming confusion. Nothing made sense. How could God promise Abraham descendants through Isaac, then command him to sacrifice that very son? Yet Abraham's response was, "Neilcha ad koh" (let us go to koh). This "koh" represents not just a physical place but a spiritual state of uncertainty where faith thrives without understanding.While we often celebrate stories where everything "works out" and makes sense in retrospect, the highest level of faith is found in continuing to trust God when Nothing seems to add up. When faced with inexplicable suffering—children dying young, righteous people suffering, evil seemingly triumphant—we don't need to torture ourselves seeking explanations. True spiritual maturity means acknowledging the limits of our understanding while maintaining unshakable trust. Perhaps this is what God meant when promising Abraham "Koh yihyeh zarecha" (so shall your offspring be)—that his descendants would inherit not just numbers matching the stars, but this profound capacity for faith amid uncertainty. Embrace the holy haze, walk toward "koh," and discover the most profound connection with the divine precisely where understanding ends.Support the showJoin The Motivation Congregation WhatsApp community for daily motivational Torah content!------------------Check out our other Torah Podcasts and content! SUBSCRIBE to The Motivation Congregation Podcast for daily motivational Mussar! Listen on Spotify or 24six! Find all Torah talks and listen to featured episodes on our website, themotivationcongregation.org Questions or Comments? Please email me @ michaelbrooke97@gmail.com
Zöldséges fasírt és málnás fagyi, ezekkel érkezik Kohári Éva gasztroblogger.
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Kacsoh Dániel, Gulyás Virág és Kohán Mátyás Nashville-ből jelentkeznek, és belecsapnak a legforróbb témákba. Szó esik az amerikai illegális migrációról, az iskolákba beszivárgó ideológiákról, Trump politikai lépéseiről, az orosz–ukrán háború jövőjéről és az EU ukrán csatlakozási terveiről.De nem marad ki Magyarország sem: kárpátaljai magyarok tragédiája, Magyar Péter politikai szerepjátéka és az európai kettős mérce is terítékre kerül.A műsor vendége: Gulyás Virág, Kohán MátyásMűsorvezető: Kacsoh DánielFelelős szerkesztő: Masszi-Rigó Tamás
“If you want to go fast, go alone. If you want to go far, go together.”This week marks a major milestone for Kreatures of Habit—we're launching our crowdfunding campaign and inviting YOU, our community, to become owners in the mission.KOH has always been built on the belief that habits create freedom and transformation—but it's the people behind those habits that create lasting change. This brand was built by the community, for the community, and now, it's time to take that to the next level.In today's Monday Moments episode, Michael gets real about what it means to join our mission, why now is the time to open the doors to investors, and how you can play a part in shaping the future of KOH.Whether you're a long-time supporter or brand new to Kreatures of Habit, this is your chance to join the movement.Learn more about becoming an owner here: https://kreaturesofhabit.com/pages/crowd
In dieser Episode des INNOQ Podcasts sprechen Michael Plöd und Sven Johann über ein Prinzip, das in der Softwarearchitektur oft genannt, aber selten genauer betrachtet wird: Kohäsion. Ausgehend von den sieben Kohäsionsarten nach Stevens, Myers und Constantine geht es um die Frage, was Module inhaltlich zusammenhält – und wie sich sinnvolle Grenzen ziehen lassen. Im Mittelpunkt steht der fachliche Zweck als Orientierung für Strukturentscheidungen. Sie sprechen über praktische Beispiele, über Methoden wie Domain-driven Design, Event Storming und die Bounded Context Canvas – und über die Möglichkeiten und Grenzen von Metriken wie LCOM.
Hey HouseHeadZ..My Guest appearance on KOH....EnJoooooY!!!!
This series celebrity historical brings us Queen Victoria as played by a previous Doscar winner. We talk the Koh-i-Noor and Balamory, but will Sarah be amused?
Dr. Harish Kinni, a triple-board-certified emergency medicine and critical care physician and assistant professor at the Mayo Clinic, provides an overview of the fundamentals of ventilator care for emergency department professionals. We will review key modes that we should know, the variables to set, how to adjust them for your patient's needs, and provide troubleshooting tips and tricks for when things suddenly go awry. This is sure to be one of the most helpful chapters of Always on EM, but don't let it take your breath away! CONTACTS X - @AlwaysOnEM; @VenkBellamkonda YouTube - @AlwaysOnEM; @VenkBellamkonda Instagram – @AlwaysOnEM; @Venk_like_vancomycin; @ASFinch Email - AlwaysOnEM@gmail.com REFERENCES & LINKS Swart P, Nijbroek SGLH, Paulus F, Neto AS, Schultz MJ. Sex Differences in Use of Low Tidal Volume Ventilation in COVID-19-Insights From the PRoVENT-COVID Study. Front Med (Lausanne). 2022 Jan 3;8:780005. doi: 10.3389/fmed.2021.780005. PMID: 35300177; PMCID: PMC8923734. McNicholas BA, Madotto F, Pham T, Rezoagli E, Masterson CH, Horie S, Bellani G, Brochard L, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group. Demographics, management and outcome of females and males with acute respiratory distress syndrome in the LUNG SAFE prospective cohort study. Eur Respir J. 2019 Oct 17;54(4):1900609. doi: 10.1183/13993003.00609-2019. PMID: 31346004. Swart P, Deliberato RO, Johnson AEW, Pollard TJ, Bulgarelli L, Pelosi P, de Abreu MG, Schultz MJ, Neto AS. Impact of sex on use of low tidal volume ventilation in invasively ventilated ICU patients-A mediation analysis using two observational cohorts. PLoS One. 2021 Jul 14;16(7):e0253933. doi: 10.1371/journal.pone.0253933. PMID: 34260619; PMCID: PMC8279424. Evans, Laura1; Rhodes, Andrew2; Alhazzani, Waleed3; Antonelli, Massimo4; Coopersmith, Craig M.5; French, Craig6; Machado, Flávia R.7; Mcintyre, Lauralyn8; Ostermann, Marlies9; Prescott, Hallie C.10; Schorr, Christa11; Simpson, Steven12; Wiersinga, W. Joost13; Alshamsi, Fayez14; Angus, Derek C.15; Arabi, Yaseen16; Azevedo, Luciano17; Beale, Richard18; Beilman, Gregory19; Belley-Cote, Emilie20; Burry, Lisa21; Cecconi, Maurizio22; Centofanti, John23; Coz Yataco, Angel24; De Waele, Jan25; Dellinger, R. Phillip26; Doi, Kent27; Du, Bin28; Estenssoro, Elisa29; Ferrer, Ricard30; Gomersall, Charles31; Hodgson, Carol32; Hylander Møller, Morten33; Iwashyna, Theodore34; Jacob, Shevin35; Kleinpell, Ruth36; Klompas, Michael37; Koh, Younsuck38; Kumar, Anand39; Kwizera, Arthur40; Lobo, Suzana41; Masur, Henry42; McGloughlin, Steven43; Mehta, Sangeeta44; Mehta, Yatin45; Mer, Mervyn46; Nunnally, Mark47; Oczkowski, Simon48; Osborn, Tiffany49; Papathanassoglou, Elizabeth50; Perner, Anders51; Puskarich, Michael52; Roberts, Jason53; Schweickert, William54; Seckel, Maureen55; Sevransky, Jonathan56; Sprung, Charles L.57; Welte, Tobias58; Zimmerman, Janice59; Levy, Mitchell60. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021. Critical Care Medicine 49(11):p e1063-e1143, November 2021. | DOI: 10.1097/CCM.0000000000005337 Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine. An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome. Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Erratum in: Am J Respir Crit Care Med. 2017 Jun 1;195(11):1540. doi: 10.1164/rccm.19511erratum. PMID: 28459336. Alhazzani W, Møller MH, Arabi YM, Loeb M, Gong MN, Fan E, Oczkowski S, Levy MM, Derde L, Dzierba A, Du B, Aboodi M, Wunsch H, Cecconi M, Koh Y, Chertow DS, Maitland K, Alshamsi F, Belley-Cote E, Greco M, Laundy M, Morgan JS, Kesecioglu J, McGeer A, Mermel L, Mammen MJ, Alexander PE, Arrington A, Centofanti JE, Citerio G, Baw B, Memish ZA, Hammond N, Hayden FG, Evans L, Rhodes A. Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19). Crit Care Med. 2020 Jun;48(6):e440-e469. doi: 10.1097/CCM.0000000000004363. PMID: 32224769; PMCID: PMC7176264. Wang W, Scharfstein D, Wang C, Daniels C, Needham D, Brower R, NHLBI ARDS Clinical Network. Estimating the Causal Effect of Low Tidal Volume Ventilation on Survival in Patients with Acute Lung Injury. J R Stat Soc Ser C Appl Stat. 2011. PMC: PMC3197806 Brower RG, Thompson BT, NIH/NHLBI/ARDSNetwork. Tidal volumes in acute respiratory distress syndrome--one size does not fit all. Crit Care Med. 2006. Hager DN, Krishman JA, Hayden D, Brower RG, ARDSNet NIH / NHLBI. Tidal Volume Reduction in Patients with acute Lung Injury When Plateau Pressures Are Not High. Am J Resp Crit Care Med. 2005. Rubenfeld GD, Cooper C, Carter G, Thompson BT, Hudson LD. Barriers to providing lung protective ventilation to patients with acute lung injury. Crit Care Med. 2004. Chatburn RL, El-Khatib M, Mireles-Cabodevila E. A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care. 2014 Nov;59(11):1747-63. doi: 10.4187/respcare.03057. Epub 2014 Aug 12. PMID: 25118309. Guo L, Wang W, Zhao N, Guo L, Chi C, Hou W, Wu A, Tong H, Wang Y, Wang C, Li E. Mechanical ventilation strategies for intensive care unit patients without acute lung injury or acute respiratory distress syndrome: a systematic review and network meta-analysis. Crit Care. 2016 Jul 22;20(1):226. doi: 10.1186/s13054-016-1396-0. PMID: 27448995; PMCID: PMC4957383. Rice TW, Wheeler AP, Bernard GR, Hayden DL, Schoenfeld DA, Ware LB, NIH NHLBI ARDS Network. Comparison of the Sp02/FI02 Ratio and the PaO 2/FI02 in Patients with Acute Lung Injury or ARDS. Chest. 2007. Zhang G, Burla MJ, Caesar BB, Falank CR, Kyros P, Zucco VC, Strumilowska A, Cullinane DC, Sheppard FR. Emergency Department SpO2/FiO2 Ratios Correlate with Mechanical Ventilation and Intensive Care Unit Requirements in COVID-19 Patients. West J Emerg Med. 2024 May;25(3):325-331. doi: 10.5811/westjem.17975. PMID: 38801037; PMCID: PMC11112664. WANT TO WORK AT MAYO? EM Physicians: https://jobs.mayoclinic.org/emergencymedicine EM NP PAs: https://jobs.mayoclinic.org/em-nppa-jobs Nursing/Techs/PAC: https://jobs.mayoclinic.org/Nursing-Emergency-Medicine EMTs/Paramedics: https://jobs.mayoclinic.org/ambulanceservice All groups above combined into one link: https://jobs.mayoclinic.org/EM-Jobs
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Jak nastavit firemní komunikaci, když firma rychle roste a má lidi navíc na různých místech? Ukážeme si to na případové studii Skladonu, který nabízí firmám fulfillment, svou centrálu a sklad má v Mošnově a kanceláře i v Praze a Ostravě. Jak to u něj funguje, si budu povídat se šéfem marketingu Tomášem Kohútem a produkťačkou Terezou Tománkovou. Tato epizoda je součástí podcastu, který pro vás od roku 2015 připravuje Jiří Rostecký. Videa k podcastům najdete na jeho webu: www.rostecky.cz (Sponzorováno) Veškerá doporučení, informace, data, služby, reklamy nebo jakékoliv jiné sdělení zveřejněné na našich stránkách je pouze nezávazného charakteru a nejedná se o odborné rady nebo doporučení z naší strany. Podrobnosti na odkazu https://rostecky.cz/upozorneni.
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Want to learn the secrets to business success from company owners who are not only surviving but thriving in this difficult economy? Then join award-winning entrepreneur Mike Bosma and his guests as they provide you with the insight and expertise you need to start a new business or to take your company to a whole new level. In between jobs? Why work for the boss when you can be the boss? With Bosma On Business you can be in conversation with the area’s top corporate executives, community leaders and movers and shakers. The show is the ultimate business networking event and entrepreneurial incubator wrapped up in one and it’s brought to you live weekly over the airwaves and through the Internet. You’ll tap into a wealth of wisdom from top experts in the fields of accounting, marketing, sales, information technology, business law, human resources, corporate real estate, banking and so much more. If you’re doing business in Northern Nevada or have the entrepreneurial itch, then plan on joining us on News Talk 780 KOH every Saturday morning at 10 a.m. With Mike Bosma, the Pied Piper of entrepreneurial excellence leading the way, we’re Getting Northern Nevada…Back to Business.See omnystudio.com/listener for privacy information.
Send us a textEpisode Summary: Join host Big Rich as he dives into the exhilarating world of off-road sports with the legendary Shannon Campbell. In this episode, Shannon shares his journey from a rural upbringing in Arizona to becoming a renowned figure in the off-road industry. From racing at Top Truck Challenge to making a mark at King of the Hammers, Shannon's stories are as thrilling as they are inspiring.Key Moments:Early Life and Influences: Shannon talks about his upbringing in Gilbert, Arizona, and how his family's involvement in racing influenced his passion for off-road sports.Breaking into Off-Road Racing: Hear about Shannon's first major competition at Top Truck Challenge in 1996 and how it set the stage for his future success.Innovations and Challenges: Discover the journey of transitioning to independent front suspension and the challenges Shannon faced in desert racing.Memorable Moments: Laugh along with tales of close calls, wild races, and the camaraderie of the off-road community, including epic stories with his long-time friend Randy Ellis.Future Plans: Shannon shares his aspirations to balance big races with a return to grassroots wheeling adventures and his enthusiasm for upcoming events like Trail Hero and the Rubicon.Guest Bio: Shannon Campbell is a celebrated figure in the off-road racing world, known for his innovative spirit and competitive drive. As a member of the Off-Road Motorsports Hall of Fame, Shannon continues to inspire with his dedication to the sport and his passion for life. Support the show
Natural disasters lead to damaged property, loss of life, psychological trauma, displaced individuals and families, among other consequences. According to the World Meteorological Organisation, the number of natural disasters has increased five times since 1970. Researchers from all over the whole world have dedicated their careers to studying natural disasters. And they all agree on one thing. The poorer people are, the more likely they are to suffer the consequences. There's a bitter irony to the fact that countries that have contributed the least to climate change are being hit the hardest by climate-related events. Are there any figures to back that up? Are there differences within a single country? What about other forms of inequality? In under 3 minutes, we answer your questions! To listen to the latest episodes, click here: What is the Koh-i-noor diamond and why is it causing so many problems for the Queen consort? What is Truth Social? What is the Karpman drama triangle? A Bababam Originals podcast written and produced by Joseph Chance. In partnership with upday UK. First broadcast : November 9, 2022 Learn more about your ad choices. Visit megaphone.fm/adchoices
Hello. → Zdravo!(ZDRAH-vo)What is your name? → Kako se zoveš?(KAH-ko seh ZO-vesh)My name is...? → Zovem se...?(ZO-vem seh...?)Where are you from? → Odakle si?(OH-dah-kleh see?)I am from Morocco. → Ja sam iz Maroka.(YAH sahm eez MAH-roh-kah)What are you doing in Sarajevo? → Šta radiš u Sarajevu?(SHTAH RAH-deesh oo SAH-rah-yeh-voo?)I am studying psychology. → Studiram psihologiju.(STOO-dee-rahm psee-HO-loh-gee-yoo)How old are you? → Koliko imaš godina?(KOH-lee-koh EE-mahsh GOH-dee-nah?)I am 75. → Imam sedamdeset pet godina.(EE-mahm SEH-dahm-deh-set peht GOH-dee-nah)Are you not too old to be studying? → Zar nisi prestar dastudiraš?(ZAHR NEE-see PREH-star dah STOO-deer-ash?)You are never too old to study. → Nikada nisi prestar daučiš.(NEE-kah-dah NEE-see PREH-star dah OO-cheesh)I love exploring Sarajevo and trying new food. → Volimistraživati Sarajevo i probavati novu hranu.(VOH-leem eess-trah-ZHEE-vah-tee SAH-rah-yeh-voh ee proh-BAH-vah-tee NOH-vooHRAH-noo)
featuring Kari and Koh! I cover Marvel's Amazing Spider-Man/Ultimate and Fantastic Four issues, DC's ALL in Special, Street Fighter x Rival Schools, Megaman, the Energon Universe and Godzilla: the New Heroes. Facebook: https://www.facebook.com/comicbookbre... Insta: https://www.instagram.com/cbbreakdown...
On the night of October 23, 1989, Charles and Carol Stuart were returning home from a childbirth class and drove through the Roxbury neighborhood of Boston. According to Charles Stuart, they were stopped at a red light when a black teenager forced the driver's door open and robbed the couple, then shot Charles and Carol before running off. Charles managed to call 911 from his car phone, but by the time emergency responders arrived, Carol was in a very bad state and would die a few hours later at a nearby hospital.The murder of Carol Stuart captured the attention of residents in and around Boston, and the story remained on the front pages in the weeks that followed. On one hand, it was a tragic story of a young couple on the verge of starting a family who were robbed of a future. On the other hand, it shined a bright spotlight on the city's long-simmer racial tensions and the unequal treatment and application of law enforcement with regard to race. And those tensions would be significantly exacerbated when the truth about Carol Stuart's murder was finally discovered.Thank you to the Incredible Dave White of Bring Me the Axe Podcast for research and Writing support!ReferencesBrelis, Matthew. 1989. "Stuart suspect held on charges." Boston Globe, November 12: 1.Canellos, Peter. 1989. "Roxbury probe is criticized." Boston Globe, November 1: 29.Canellos, Peter, and Irene Sege. 1989. "Couple shot after leaving hospital; baby delivered." Boston Globe, October 24.Cullen, Kevin. 1989. "Stuart suspect linked to Brookline case." Boston Globe, November 13: 1.Hayes, Constance L. 1990. "Illusion and tragedy coexist after a couple dies." New York Times, January 7.Howe, Peter, and Jerry Thomas. 1989. "Reading woman dies after shooting in car." Boston Globe, October 25.Howe, Peter, Kevin Cullen, and Anthony Flint. 1990. "Police focus on brother, woman." Boston Globe, January 8: 1.Jacobs, Sally. 1989. "Stuart is said to pick out suspect." Boston Globe, December 29: 1.—. 1989. "Stuart reportedly reacted physically to suspect's picture." Boston Globe, November 23: 93.Jacobs, Sally, and Diego Ribadeneira. 1989. "No wallet, so killer opened fire." Boston Globe, October 26: 1.Koh, Elizabeth. 2023. "Stuart shooting timeline." Boston Globe, December 1.Kong, Dolores, and Sally Jacobs. 1989. "Infant of shooting victims dies of respiratory failure." Boston Globe, November 10: 1.Murphy, Sean. 1989. "Man questioned in shooting still held." Boston Globe, November 7: 17.New York Times. 1991. "U.S. won't indict Boston policemen." New York Times, July 5: D7.Rollins, Rachel. 2019. "30 years after Stuart case, Boston still healing." Commonwealth Beacon, November 9.Sharkey, Joe. 2015. Deadly Greed: The Riveting True Story of the Stuart Murder Case. New York, NY: Simon and Schuster.Walker, Adrian, Evan Allen, Elizabeth Koh, Andrew Ryan, Kristin Nelson, and Brendan McCarthy. 2023. "The untold story of the Charles and Carol Stuart shooting." Boston Globe, December 1.Stay in the know - wondery.fm/morbid-wondery.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Michael Chernow has lived a few different lives—bartender, restaurant owner, wellness junkie, and now founder of Kreatures of Habit, a CPG (consumer packaged goods) brand built around healthy routines and real-life lessons. In this episode, Michael gets real about the highs and lows: growing up in NYC, getting sober, building restaurants, and starting over in a completely different industry.We talk about the messy stuff—mistakes, mindset shifts, burnout—and how those tough moments actually laid the groundwork for what he's doing now. If you're building a business, changing careers, or just trying to get your habits on track, this one's full of gold.Hit play, and maybe grab a notebook, as Michael shares about:Growing up in NYC: Michael's early influencesGetting sober: The turning point that changed everythingEntering the restaurant world: From vision to reality, and the beginning of Michael's entrepreneurial journeyLaunching Kreatures of Habit: The series of events that led KOH to being a CPG brandIf you loved today's show, please spread the love by leaving the show a 5-star rating and review. And if you really really loved it, share it with a friend that would enjoy following along on our journey as well! Until next week, Kreatures. Let's do this thing!TIMESTAMPS:2:06 Growing up in NYC10:14 Getting sober16:49 Entering the restaurant world21:28 Launching Kreatures of Habit