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In this episode, we discuss the anti-aging effects of therapeutic plasma exchange (TPE) with Dr. Irina Conboy, a professor in the Department of Bioengineering at UC Berkeley. Her current research focuses on unraveling the key signal transduction pathways that regulate adult stem cell behavior – and understanding how these pathways change with age… From synthetic biology to CRISPR technologies, Dr. Conboy has been working in the fields of aging and genetic diseases for decades. Is aging a disease that can be solved? If so, what role does TPE play in it? If you're interested in the mysterious topic of human aging, this podcast is undoubtedly for you! Jump in to find out: What TPE is, and what it's used for. The benefits of “rebooting” blood signal proteins. What blood plasma is, and how it is produced in the human body. How TPE is linked to anti-aging. You can follow along with Dr. Conboy and her lab's work here. Episode also available on Apple Podcasts: http://apple.co/30PvU9C
Leah Linder is a naturopathic physician with a focus on botanicals and nutrition, and expertise in natural supplement formulation and manufacture. She is also a Master Gardener. Pam Conboy is a doctoral student in naturopathic medicine. She has spent her professional years educating practitioners about nutritional supplementation. Both are ordained ministers and shamanic practitioners. Here they and Dawson discuss: Research on psilocybin for PTSD and addictions Microdosing Plant medicine for profound understanding of something beyond self Lifestyle management Serotonin receptors which synthesizes other neurotransmitters Transcendence of self Dopamine and oxytocin Failure to seek social support The many layers of trauma For more information about Leah and Pam: https://www.setasseminary.org/ View Dawson's work at: http://dawsongift.com/ And to preorder Dawson's next book, Spiritual Intelligence: https://www.amazon.com/Spiritual-Intelligence-Activating-Circuits-Awakened/dp/160415294X/ #mindtomatter #blissbrain #spiritualintelligence #eft #meditation #highenergyhealth #naturalsupplementation #trauma #psilocybin
Rob Conboy, CEO of Glavel, shares his journey from working at Burton to founding a company that transforms recycled glass into sustainable insulation. He reflects on how Vermont's emphasis on sustainability and innovation inspired him to bring foam glass technology from Europe to the U.S. Rob explains how Glavel's products reduce embodied carbon in construction, create green jobs, and help companies meet their sustainability goals. He also discusses local Vermont partnerships that will make Glavel 100% renewable next year. Rob's journey will encourage you to #starthere in beautiful Vermont! Hosted on Acast. See acast.com/privacy for more information.
This episode is sponsored by:INICIO Windows + Doorshttps://iniciowindows.com/Contact: Randy McMurrayThis episode is with Laura DuCharme Conboy, AIA of DuCharme ArchitectureLink to BL?OG with Images here: https://inmawomanarchitect.blogspot.com/2024/12/this-podcast-episode-is-sponsored-by.htmlLaura is a licensed architect, and principal of DuCharme Architecture, which she founded in 1992, specializing in custom residential design.Laura serves as vice-president of the La Jolla Historical Society, and annually conducts their Young Architect Summer Program for middle and high school students. She is also serves on the board of the San Diego Architectural Foundation, and co-chairs BEEP, their Built Environment Education Program, which is dedicated to introducing architecture, planning, and urban design to school-aged students. You can also find her online hosting monthly sketching sessions known as Crossing the Line – which are available on YouTube.Link to website: https://www.ducharmearch.com/contactLink to website: https://www.ducharmearch.com/This episode is sponsored by Link to MGHarchitect: MIchele Grace Hottel, Architect website for scheduling and podcast sponsorship opportunities:https://www.mgharchitect.com/
In this fascinating conversation for the MindHealth360 Show, Pam Conboy and Leia Linder discuss an imminent and radical approach to mental health treatment: psychedelic therapy. When combined with spirituality, community, and functional medicine, this approach can be incredibly powerful for brain restoration, neuroplasticity, and mental healing. Pam Conboy is a biologist and clinical laboratorian who has worked most of her life in medical marketing but has been working in Naturopathic Functional Medicine spheres for the last 7 years, transforming her approach and understanding of medicine. Leia Linder is a naturopathic physician. Following significant patient interest in the healing power of psychedelics, she was blown away by the wealth of research on the power of psilocybin to successfully address depression, anxiety, PTSD, and many other mental health conditions as a breakthrough therapy endorsed by the 2018/19 US Food and Drug Administration. Reconnecting a year ago, they discovered how psilocybin can be used legally and therapeutically in the context of a religious entity. Founders of the Setas Seminary Church of Spiritual Integration, the first legitimate non-profit church using psilocybin for therapeutic use under the Religious Freedom Act, their treatments sincerely incorporate elements of naturopathic medicine, holistic spirituality, and psychedelic-assisted therapy. In this groundbreaking interview, they explain the remarkable effects of psilocybin on our biochemistry to reveal why it can not only powerfully and sustainably address mental health issues such as depression, anxiety, and PTSD when used in an integrative and therapeutic way but can also be truly life-changing for those who use it. In this episode, learn about: How the Religious Freedom Act enables the use of psilocybin within the church setting. Ways psilocybin kickstarts the healing process, and why it works significantly more effectively than antidepressants via the 5-HT serotonin receptors. How microdosing can help individuals taper off SSRIs. Why the therapeutic space is key and the importance of the therapist witnessing/holding in the healing journey. How recreational use can go wrong, and why the Church hasn't seen a 'bad trip.' Why the psilocybin used in the Church is safer than SSRI medications, where their psilocybin is sourced, and the rigorous testing involved. The three therapeutic psilocybin dosing categories, and the circumstances in which they are applied: 1) micro-dosing 2) moderate dose 3) full dose Ways the full dose generates a significant psychedelic experience, why it is taken in ceremony and how it works long-term. How psilocybin can create neural pathways/connections, as shown in MRI scans, and how it can vastly increase neuroplasticity and the growth of brain cells quickly – giving sufferers a jump start into better mental health. Why whole mushrooms, rather than molecules, are used and ways they are anti-inflammatory. Why psilocybin is only one of many tools in the healing toolkit, and why the integration of community, naturopathic medicine, EMDR, light therapy, etc., is also vital, and how the Church facilitates this approach. The early research showing that psilocybin can prevent neurodegenerative diseases and stabilize the endocrine system, pointing toward its potential to treat many areas of poor health. Some incredible case stories from churchgoers, ways it can unexpectedly bring to the forefront and heal past traumas, and why psilocybin therapy can be life-changing. For further insights, visit www.mindhealth360.com – your comprehensive guide to mental well-being.
Dr. Kim and Dr. Conboy discussed parenting challenges and personal growth, emphasizing the need for a balance between parental involvement and individual agency. They explored the impact of overly controlling or harsh parenting styles on adult children and the importance of learning to fail gracefully. The speakers also grappled with the challenges of balancing love and freedom in parenting and emphasized the importance of empathy, self-awareness, and unconditional support for children's personal growth. They concluded by acknowledging the complexities of parenthood and the need to navigate the transition from being a parent to a coach or friend.Sign up for a newsletter: http://eepurl.com/iSnP_EDr. Kim's private practice: www.restorepsych.comFind this podcast in your favorite Podcast Platform**Disclaimer: This site's content is not intended to diagnose or treat any disorders but rather for informational, educational, and empowerment purposes. Please consult with your physician or mental health provider for specific medical and mental health needs. Our connection via social media platforms does not constitute a patient-physician relationship.**Dr. Kim's private practiceSpeakpipe to send Dr. Kim your questions
The Ilumed team is noted for their expertise in risk management and a deep commitment to putting patients first, which is evident throughout the company. In this episode, Melissa Conboy, Marketing Director at Ilumed, discusses how the company partners with physicians and health systems to transition patients to value-based care. She highlights CMMI's temporary but promising program, which aims to improve patient health outcomes and reduce Medicare spending. Mel shares a recent case study from a rural health clinic in West Virginia that saw increased annual wellness visits and better patient outcomes. She also explains why the illumed team is praised for their expertise in risk management and their deep commitment to patient care. Join us and discover the growing importance of value-based care in healthcare's future! Resources: Watch the entire interview here. Connect and follow Melissa Conboy on LinkedIn. Learn more about Ilumed on their LinkedIn and website.
Graymoor farm grows produce, sobriety Bounty is everywhere on the grounds of San Damiano Farm at Graymoor, the Philipstown home of the Franciscan Friars of the Atonement. Vegetables and flowers sprout from an array of raised garden beds, the progeny of a wet winter and spring, and the sweat of Derek Fox and other men. Fox is also blooming. He first entered St. Christopher's Inn, the friar's treatment program for men, in 2007, and achieved five years of sobriety before relapsing. He returned in August 2023 and, after graduating, moved on May 1 into San Damiano House, a transitional program just a short walk from St. Christopher's. "I wasn't even sure I wanted to do this," he said of returning to St. Christopher's. "But after a couple of weeks, the thirst came back of wanting to stay sober." St. Christopher's graduates sharing the same desire have planted, weeded and harvested at San Damiano since 2017, when the Franciscan Friars rescued an itinerant farming program for homeless men that a New York City nonprofit, Project Renewal, once operated on a plot at the Garrison Golf Course. Men who choose San Damiano over returning home or entering other transitional programs are required to work the farm for three hours each morning during a three-month waiting period before they can look for jobs in the community. Bob Conboy, a Garrison resident and the farm's longtime manager, imparts lessons in planting and growing the basil, carrots, eggplant, lettuce, sunflowers, tomatoes and other herbs, vegetables and flowers sold at the San Damiano farmers market on Fridays. Three restaurants - Riverview in Cold Spring, the Valley Restaurant in Garrison and the Farm to Table Bistro in Fishkill - also buy produce, said Conboy. Other lessons come from toiling outdoors on hot days and collaborating in the arduous work of farming, challenges that inculcate traits - a willingness to learn and take direction, patience and perseverance - needed to stay sober. An added reward, said the men, is seeing the seeds they plant and nurture flourish. "We spend a lot of time in the brutal heat, getting the beds ready, and it's just a pile of dirt," said Greg Miller. "Then, a few weeks later, you have these beautiful sunflowers." On a recent Wednesday, Miller and the other men listened as Conboy prepped them before they began planting bush beans, carrots and string beans in several of the farm's 245 raised beds. He told the men they needed to space the pelleted carrot seeds between 1 and 1 inches apart in the 10-inch-deep beds. San Damiano's farm has its roots in Renewal Farm, which launched at Camp LaGuardia, a homeless shelter that New York City opened in Chester. When Camp LaGuardia closed in 2007, the farm moved to The Garrison on Route 9. Two dozen men who stayed in dormitories at St. Christopher's planted and harvested produce, selling part of their yield from a roadside stand on Route 9. Graymoor began hosting the farm in 2011, repurposing badminton, basketball, handball and tennis courts built for a once-planned seminary. Facing financial difficulties, Project Renewal pulled out in 2017 but Graymoor decided to continue the program. Conboy, a former English teacher who retired nearly 20 years ago as chief financial officer for the Edgemont School District, began his journey to farm manager by volunteering with Renewal Farm when it moved to The Garrison. His farming lessons came from Brian Bergen, who grew organic produce at The Garrison's farm for the Valley Restaurant, as well as trial and error. His students have raised herbs such as oregano, thyme and sage, which Conboy highlighted as he walked rows of beds. Conboy pointed out Badger flame beets that look like sweet potatoes, eggplants, Swiss chard and Tuscan kale, all grown without pesticides and using compost from two piles stored at a former handball court. He pulled at some plants to uproot a handful of baby potatoes and passed beds with butternut squash, white onions. coleus and dahlias, all fl...
In this episode, we discuss the anti-aging effects of therapeutic plasma exchange (TPE) with Dr. Irina Conboy, a professor in the Department of Bioengineering at UC Berkeley. Her current research focuses on unraveling the key signal transduction pathways that regulate adult stem cell behavior – and understanding how these pathways change with age… From synthetic biology to CRISPR technologies, Dr. Conboy has been working in the fields of aging and genetic diseases for decades. Is aging a disease that can be solved? If so, what role does TPE play in it? If you're interested in the mysterious topic of human aging, this podcast is undoubtedly for you! Jump in to find out: What TPE is, and what it's used for. The benefits of “rebooting” blood signal proteins. What blood plasma is, and how it is produced in the human body. How TPE is linked to anti-aging. You can follow along with Dr. Conboy and her lab's work here. Take advantage of a 5% discount on Ekster accessories by using the code FINDINGGENIUS. Enhance your style and functionality with premium accessories. Visit bit.ly/3uiVX9R to explore latest collection. Episode also available on Apple Podcasts: http://apple.co/30PvU9C
In this episode, Dr. Inna Conboy and I have an open dialogue about the impossible standards of perfectionism in parentinghow social media expediated parenting burdenhow to embrace the concept of "Good enough mom"the benefits of not being perfecthow to find your "style" in parentingwhat to do when you mess up in your familyThis episode is a perfect example of the vulnerable human connection... which is what we all need and want! I hope you find some encouragement today that you are not alone! Inna Conboy, M.D. (she/her/hers) is a Board Certified Psychiatrist who specializesin psychoanalytic psychotherapy and medication management. Dr. Conboy'streatment philosophy centers around an empathic view of the person as a whole andexplores the patient's past and present to understand his/her/their currentthoughts and feelings. As a person attains a deeper understanding of self, thisawareness may help with his/her/their life struggles. Dr. Conboy graduated from New Jersey Medical School, NJ, and completedpsychiatry residency at Temple University, PA. In addition, she was trained inpsychodynamic psychotherapy at the Psychoanalytic Center of Philadelphia. Dr.Conboy was a recipient of various teaching awards and certificates and has beenteaching psychiatry to La Salle University and Philadelphia College of OsteopathicMedicine medical, nurse practitioner, and physician assistant students. She has givenlectures to psychiatry and psychology professionals in various topics, includingpsychotherapy, psychopharmacology, emotional intelligence, and the use ofmindfulness meditation in psychiatry. Dr. Conboy's greatest love is her family. She resides in Pennsylvania with her husband, two young daughters, two dogs, and a cat.https://www.conboypsychiatryllc.com/#parenting #perfectionism #authentic #humanconnection #mentalhealth #freedomFind this podcast in your favorite Podcast Platform**Disclaimer: This site's content is not intended to diagnose or treat any disorders but rather for informational, educational, and empowerment purposes. Please consult with your physician or mental health provider for specific medical and mental health needs. Our connection via social media platforms does not constitute a patient-physician relationship.**Dr. Kim's private practiceSpeakpipe to send Dr. Kim your questions
Join host Rick Thomas as he dives into the world of yacht building with industry veteran Thom Conboy of Heesen Yachts. From Conboy's early days aboard the SY Raglin to his contributions to cutting-edge projects, explore the evolution of yacht construction and the rise of larger, technologically advanced vessels. Discover the significance of the Tampa Bay area in yacht building and gain insights into the industry's current state in the U.S. versus Holland. Stay tuned for a glimpse into Heesen Yachts' legacy of innovation and an upcoming segment featuring Niels Vaessen, Heesen's new CEO, discussing the future of yacht building. Don't miss this engaging conversation on Yachting USA Podcast! For Heesen Yachts: heesenyachts.com @heesenyachts - Instagram/Facebook/LinkedIn/YouTube For Rick Thomas: Email: Rick@rt-yd.com LinkedIn: https://www.linkedin.com/in/rick-thomas-51909821/ #Yachting #YachtBuilding #HeesenYachts #TomConboy #NielsVlasen #YachtConstruction #Innovation #TampaBay #IndustryInsights #Podcast
In the season 2 premiere episode of the Longevity & Aging Series, Dr. Irina Conboy and Xiaoyue (Serafina) Mei from the Department of Bioengineering and QB3 at the University of California, discuss a research paper they co-authored that was published in Volume 15, Issue 17, of Aging (Aging-US), entitled, “Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease.” DOI - https://doi.org/10.18632/aging.205046 Corresponding Author - Irina M. Conboy - iconboy@berkeley.edu Video interview - https://www.youtube.com/watch?v=aYhUPpEPVv4 Transcript - https://aging-us.net/2024/04/22/longevity-aging-series-s2-e1-dr-irina-conboy-and-xiaoyue-serafina-mei/ Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.205046 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, DNA methylation, epigenetics, clocks' fail-test, biological noise About Longevity & Aging Series In its second season, the Longevity & Aging Series is a monthly video series that features esteemed researchers discussing the latest in aging research with a focus on their studies published by Aging (Aging-US). Learn more - https://www.aging-us.com/longevity About Aging-US Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer's diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan. The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases. Aging is indexed by PubMed/Medline (abbreviated as “Aging (Albany NY)”), PubMed Central, Web of Science: Science Citation Index Expanded (abbreviated as “Aging‐US” and listed in the Cell Biology and Geriatrics & Gerontology categories), Scopus (abbreviated as “Aging” and listed in the Cell Biology and Aging categories), Biological Abstracts, BIOSIS Previews, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM
BUFFALO, NY - April 22, 2024 – The Longevity & Aging Series is an enlightening and progressive video interview series presented by Aging, featuring esteemed researchers discussing the latest in aging research, with a focus on their studies published by Aging. In the premiere episode of the second season of the Longevity & Aging Series, Dr. Irina Conboy and Xiaoyue (Serafina) Mei from the Department of Bioengineering and QB3 at the University of California, Berkeley, discuss a priority research paper they co-authored and published in Aging's Volume 15, Issue 17, entitled, “Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease.” DOI - https://doi.org/10.18632/aging.205046 Corresponding Author - Irina M. Conboy - iconboy@berkeley.edu Video - https://www.youtube.com/watch?v=aYhUPpEPVv4 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.205046 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, DNA methylation, epigenetics, clocks' fail-test, biological noise About Aging-US Aging publishes research papers in all fields of aging research including but not limited, aging from yeast to mammals, cellular senescence, age-related diseases such as cancer and Alzheimer's diseases and their prevention and treatment, anti-aging strategies and drug development and especially the role of signal transduction pathways such as mTOR in aging and potential approaches to modulate these signaling pathways to extend lifespan. The journal aims to promote treatment of age-related diseases by slowing down aging, validation of anti-aging drugs by treating age-related diseases, prevention of cancer by inhibiting aging. Cancer and COVID-19 are age-related diseases. Aging is indexed by PubMed/Medline (abbreviated as “Aging (Albany NY)”), PubMed Central, Web of Science: Science Citation Index Expanded (abbreviated as “Aging‐US” and listed in the Cell Biology and Geriatrics & Gerontology categories), Scopus (abbreviated as “Aging” and listed in the Cell Biology and Aging categories), Biological Abstracts, BIOSIS Previews, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). Please visit our website at https://www.Aging-US.com and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM
Episode 438 - Ian Conboy, Lucky Hare Brewing Happy Monday, Thieves! We spent St. Patrick's Day catching up with Ian Conboy of Lucky Hare Brewing in the Finger Lakes. We have a great discussion about brewing in NY State and have some fun in the black glasses, to boot. Tune in and let us know what you think!***As always, you can email your questions, complaints, whimpers, or whines to us at stealthisbeerpodcast@gmail.com. We read everything we get and we'll try to respond as quickly as we can. If not online, then on air. And THANKS! You can subscribe to STB on iTunes and PLEASE LEAVE US A REVIEW!!! Co-hosts: Augie Carton & John Holl Producer: Justin Kennedy Engineer: Brian Casse Music: "Abstract Concepts - What Up in the Streets" by Black Ant.
Roy's poem Tia Mary combines playfulness and poignancy in one beautiful punch. Roy Conboy is a Mixed Blood Latino/Irish/Indigenous writer and teacher who's poetic plays have been seen in the struggling black boxes on the edges of the mainstream theatre in Los Angeles, Santa Ana, San Francisco, San Antonio, Denver, and more; and whose musical plays for young people have toured extensively in California. His poetry has been seen in Green Hills Literary Lantern, Orphic Lute, Third Estate's Quaranzine, Freshwater Literary Journal, New American Writing, and featured on the Latinx Lit podcast. His poetic radio drama Hue can be heard online at Barewire Theatre Company. As an educator he taught for 35 years, including three decades as the head of the San Francisco State University playwrighting program where he created multiple programs that gave thousands of students of diverse ethnicities, genders, and backgrounds a place to find and raise their voices. You can catch his work at royconboy.net
If you write about family that's still living, do you still get to go to the family reunions? Can you really put pomegranate seeds in tacos and retain your Mexican license? Get the answer to these hard-hitting questions in this episode of Latinx Lit Audio Mag. Roy Conboy is a Mixed Blood Latino/Irish/Indigenous writer and teacher who's poetic plays have been seen in the struggling black boxes on the edges of the mainstream theatre in Los Angeles, Santa Ana, San Francisco, San Antonio, Denver, and more; and whose musical plays for young people have toured extensively in California. His poetry has been seen in Green Hills Literary Lantern, Orphic Lute, Third Estate's Quaranzine, Freshwater Literary Journal, New American Writing, and featured on Latinx Lit Magazine's podcast. His poetic radio drama Hue can be heard online at Barewire Theatre Company. As an educator he taught for 35 years, including three decades as the head of the San Francisco State University playwrighting program where he created multiple programs that gave thousands of students of diverse ethnicities, genders, and backgrounds a place to find and raise their voices. Check out his work at royconboy.net.
Rob Conboy from Glavel, a foam glass gravel manufacturer out of Burlington VT, talks about the versatile and lightweight building material.
A new priority research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, “Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease.” In this new study, researchers Xiaoyue Mei, Joshua Blanchard, Connor Luellen, Michael J. Conboy, and Irina M. Conboy from the University of California, Berkeley, show that Elastic Net (EN) DNA methylation (DNAme) clocks have low accuracy of predictions for individuals of the same age and a low resolution between healthy and disease cohorts; caveats inherent in applying linear model to non-linear processes. “We found that change in methylation of cytosines with age is, interestingly, not the determinant for their selection into the clocks.” Moreover, an EN clock's selected cytosines change when non-clock cytosines are removed from the training data; as expected from optimization in a machine learning (ML) context, but inconsistently with the identification of health markers in a biological context. To address these limitations, the researchers moved from predictions to measurement of biological age, focusing on the cytosines that on average remain invariable in their methylation through lifespan, postulated to be homeostatically vital. They established that dysregulation of such cytosines, measured as the sums of standard deviations of their methylation values, quantifies biological noise, which in their hypothesis is a biomarker of aging and disease. “We term this approach a ‘noise barometer' - the pressure of aging and disease on an organism.” These noise-detecting cytosines are particularly important as sums of SD on the entire 450K DNAme array data yield a random pattern through chronology. Testing how many cytosines of the 450K arrays become noisier with age, the team found that the paradigm of DNAme noise as a biomarker of aging and disease remarkably manifests in ~1/4 of the total. In that large set even the cytosines that have on average constant methylation through age show increased SDs and can be used as noise detectors of the barometer. DOI - https://doi.org/10.18632/aging.205046 Corresponding author - Irina M. Conboy - iconboy@berkeley.edu Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.205046 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, DNA methylation, epigenetics, clocks' fail-test, biological noise About Aging-US Launched in 2009, Aging-US publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging-US go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways. Please visit our website at https://www.Aging-US.com and connect with us: SoundCloud - https://soundcloud.com/Aging-Us Facebook - https://www.facebook.com/AgingUS/ Twitter - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Media Contact 18009220957 MEDIA@IMPACTJOURNALS.COM
Andrew Conboy enjoys sharing his passion for trees and their many benefits with anyone who will listen. He is an ISA-certified arborist who most recently worked on the Urban Forestry team at the Morris Arboretum in Philadelphia. In 2020, he created Colonial Canopy Trees, a non-profit organization that leads ecological restoration efforts in the greater Philadelphia area. In his free time, Andrew creates videos about environmental topics and shares them on social media. Through his work, he hopes to inspire people and change the way we view and value our natural lands, native plants, and wildlife. He studied Environmental Science at Chestnut Hill College and Evolutionary Biology in graduate school at Lehigh University. After retiring in 2020, Karen Kabnick wanted to do everything she could to help mitigate the damages of climate change and habitat destruction. Karen met Andrew at a volunteer event and was thrilled to learn he, too, loved to rescue and nurture seedlings of native trees. They shared that hobby. She learned all about the countless benefits of trees and how to plant them from Andrew, friends, courses and reading, and wanted to use her new-found knowledge to help Andrew with Colonial Canopy Trees to restore our local canopy and re-establish wildlife habitats. --- Send in a voice message: https://podcasters.spotify.com/pod/show/plantatrilliontrees/message Support this podcast: https://podcasters.spotify.com/pod/show/plantatrilliontrees/support
The Keep Henrico Beautiful Committee recently selected the winners of its annual awards program that recognizes properties that are beautifully landscaped and highlight best practices for soil and water conservation and garden habitats. In its 28th year, the program is honoring each magisterial district's recipient of the Land Lover Award and a countywide winner of the Clean Business Award. Winners were recognized at the Henrico Board of Supervisors meeting June 28. The winners of the Land Lover award for residential properties are: • J.T. and Betty Millard, of the Brookland District; • the Conboy family, of the Fairfield District; •...Article LinkSupport the show
Today, we get to explore the fascinating area of parabiosis transfusions and how these deal with longevity. And we're fortunate to have a world expert on the area, Dr. Irina Conboy.LINK:The Conboy Laboratory - Websiteiconboy@berkeley.eduIrina Conboy - Faculty at UC BerkeleyTIMESTAMPS:00:47 - Parabiosis02:58 - Antagonistic Pleiotropic08:08 - DNA12:52 - Senescence13:53 - Blood Transfusion14:55 - Rejuvenate15:15 - Conboy Laboratories16:14 - Plasmapheresis16:22 - Toxins18:29 - Senolytics----------#IrinaConboy #antibodies #parabiosis #neurogenesis #albumin #methylationclocks #hippocampus #BDNF #plasma #TheConboyLaboratory #robertlufkinmd #drlufkin #robertlufkin #stephensideroff #drsideroff #stephensideroffphd #healthlongevitysecrets #pathlongevity*** CHECK OUT ROB AND STEVE'S MASTERCLASSES ***Rob's MasterclassesSteve's Masterclasses*** CONNECT WITH ROBERT LUFKIN MD ON SOCIAL MEDIA ***Web: https://robertlufkinmd.com/Twitter: https://twitter.com/robertlufkinmdYoutube: https://www.youtube.com/RobertLufkinMDInstagram: https://www.instagram.com/robertlufkinmd/*** CONNECT WITH STEPHEN SIDEROFF PHD ON SOCIAL MEDIA ***Facebook: https://www.facebook.com/stephen.sideroffTwitter: https://twitter.com/DrSideroffInstagram: https://www.instagram.com/drstephensideroff/LinkedIn: https://www.linkedin.com/in/drstephensideroff/*** SPONSORSHIPS & BRANDS ***We do work with sponsors and brands. If you are interested in working with us for your health industry product or service, please contact us at:https://pathlongevity.com/contact-us/ NOTE: This is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have. Never disregard professional medical advice or delay in seeking it because of something you have seen here. Robert Lufkin MD may at any time and at its sole discretion change or replace the information available on this channel. To the extent permitted by mandatory law, Robert Lufkin MD shall not be liable for any direct, incidental, consequential, indirect or punitive damages arising out of access to or use of any content available on this channel, including viruses, regardless of the accuracy or completeness of any such content.
Ross catches up with Interior Photographer Sean Conboy. We delve into the mind of a world class interior photographer and discuss the changes over the years from film to digital. Both Sean and I were late adopters of digital captures and this is a great listen for any photographer.Recorded at The Societies Convention 2022.A bit about Sean : An internationally renowned photographer, Sean Conboy provides architects, construction companies, designers and the world of advertising and marketing with a standard of work that only leaves you questioning the standards of others.With projects ranging from giant multiplex cinemas to multi-storey structures, Sean Conboy is often challenged with complex mixed lighting and atmospheric surroundings. A keen visual awareness, extensive technical experience and the finest large format equipment ensure you a result that simply can't be found anywhere else.Sean Conboy uses a variety of camera systems and equipment that enables him to consistently produce the some of the best architectural, industrial and commercial photography in the world.Sean is a Hasselblad AmbassadorCheck out more about Seans work at his website and for his workshops: https://seanconboy.com
I'm honored to share this throwback episode with a mentor and coach who has had a tremendous impact on the person and parent I am today, Leslie Medine. I released this episode on December 21st, 2020, on the winter solstice, the darkest day of the year in the northern hemisphere, in honor of a great coach Leslie and I had in common, Edd Conboy, who passed away in March of the same year. You'll notice it's longer than my usual ones and I also hope you'll find tremendous value in listening. Find a cozy spot and a cup of tea and settle in. Or if you are more limited in your time, listen for some while, and then press pause and come back when you're ready. Make sure not to listen with your little ones present as there is some colorful language. Seize the time and space for yourself. And let the light in. Much appreciation, — Full Episode Show Notes Check out the full show notes from the original episode here: www.mothersquest.com/80 Mother's Quest is a podcast for moms who are ready to live a truly E.P.I.C. life. Join in for intimate conversations with a diverse group of inspiring mothers as they share how they are living an E.P.I.C. life, Engaging mindfully with their children (E), Passionately and Purposefully making a difference beyond their family (P), Investing in themselves (I), and Connecting to a strong support network (C). Join our community of mothers to light the wAay and sustain you on your quest at https://www.facebook.com/groups/mothersquest/
Ep 10---Welcome to our latest episode, where we will be sharing our recent chat featuring a special guest from the town of Boyle: Tony Conboy.Tony is a longtime resident of Boyle, arriving in 1972 to take up a teaching position in St. Mary's College.In this episode, I had a great chat with Tony about his experiences growing up in Castlecoote, his memories, and his insights on life in Boyle.Since coming to Boyle in the early 1970's, Tony has been a prominent member of the community, serving as a teacher for 29 years as well as been involved in a number of different groups and organisations. He has also written a number of booklets on local history and about the history of Roscommon GAA.We hope that you will join us for this fascinating conversation with a true Boyle local. Check out the full blog post that accompanies this episode by clicking the following link:https://www.voicesofboyle.com/tonyconboy/Join us on:( Facebook ) ( Instagram ) You can support the Voices of Boyle Podcast by clicking here. If you'd like to be on the show or if you know someone who would like to chat with us, then drop us an email at ( info@voicesofboyle.com ) Thanks to Brendan O' Dowd for creating and recording the musical piece for the podcast.
We talked to the amazing (now purple belt) Dr. Erin Conboy! We talked about her then first, NOW SECOND, Masters World Blue Belt Champion title as well as her amazing carrier in Pediatric Genetic Biology! What can this woman not do? Bonus content at the very end (trigger warning for mouth chewing sounds). ENJOY!
Passive House Podcast cohost Zack Semke catches up with co-founder and CEO of Glavel, Rob Conboy. The two discuss the new production facility for the foam glass gravel manufacturer, based in Vermont, and the steps Glavel has taken to produce its product with clean energy, dramatically reducing the embodied carbon of the material. Rob shares what advice he would give his past self as he was just getting started with building Glavel, as well as Glavel's work in progressive hiring practices. He also discusses Glavel's plans for future expansion out west. https://www.glavel.com/ To learn more and to request product samples, visit: https://www.glavel.com/learn/ Thank you for listening to the Passive House Podcast! To learn more about Passive House and to stay abreast of our latest programming, visit passivehouseaccelerator.com. And please join us at one of our Passive House Accelerator LIVE! zoom gatherings on Wednesdays.
Welcome back and thank you for joining us for another episode of Don't Know Her? As we enter spooky season, we simply had to turn our attention to a Halloween favourite and Christina Ricci was one of the first that sprang to mind. We were delighted to also be accompanied by our special guest, Kate Conboy-Fischer to chat all things Christina. Forever seared into our heads as Wednesday Addams in The Addams Family and Addams Family Values (Barry Sonnenfeld, 1991 and 1993), she has become a Halloween staple in many households. Couple this with her work in Casper (Brad Silberling, 1995) and Sleepy Hollow (Tim Burton, 1999) and you have all the spooky season delights you could need. Alongside some of these seasonal classics, we delve into some of Christina's other career highlights, such as Buffalo ‘66 (Vincent Gallo, 1998), Black Snake Moan (Craig Brewer, 2006), Mermaids (Richard Benjamin, 1990), Monster (Patty Jenkins, 2003), Penelope (Mark Palansky, 2006) and 10 Things We Should Do Before We Break Up (Galt Niederhoffer, 2020). This episode's quiz pits Kate against Michael as we determine who has the better ear for witches on film. There were also cackles galore. NOTE: This episode was recorded on the 3rd of October and mentions the iconic Angela Lansbury, in a celebration of one of cinema's greatest witches, ahead of her passing on the 11th of October. We were truly spoiled for choice in what to talk about for Christina, but we wish she was getting film opportunities as exciting as we got in the 90s and 00s, so the three of us submit some fantasy film roles we'd love to see in her future to wrap up the episode. Please join us, enjoy this episode and follow us on social media to stay updated! We're @dontknow_her on Twitter and Instagram. And you can support us here. --- Send in a voice message: https://anchor.fm/dontknowherpod/message
In this very special episode we say goodbye to a dear friend, and bring you TWO MID world exclusives, live tattooing and an episode where the main point of the podcast is forgotten! Jordan and Aisling discuss confirmation names, Aisling's departure to Manchester, and the medical condition known as 'bollock tongue'. We also hear about Jordan's campaign to have the Pope bless Shrek's swamp. Join us as we take an in depth and unqualified look into the google searches of our guests. Each episode we click the 'I'm Feeling Lucky' button of their minds to find the sometimes weird, but always wonderful, reasons behind each search.
This week our guest, Aisling Conboy, dishes the dirtiest of dirt on the worst and best celebrity interviews she has done, and also tells of how she discovered a gruesome murder plot in her own backyard! Join us as we take an in depth and unqualified look into the internet searches of our guests. Each week we click the 'I'm Feeling Lucky' button of their minds to find the sometimes weird, but always wonderful, reasons behind each search.
Roy talks about the way he crafts his poetry to showcase the layers of his identity--Indigenous/Latino/Irish. He says (to paraphrase) that we're often like a car speeding down the road, dropping things to lighten the load. Often, one of the things we drop is culture. His job as a writer and a teacher involves stopping the car and picking up the things that shouldn't have been dropped. Roy Conboy is a Latino/Irish/Indigenous writer and teacher whose poetic plays have been seen in the struggling black boxes on the edges of the mainstream theatre in Los Angeles, Santa Ana, San Francisco, San Antonio, Denver, and more; and whose musical plays for young people have toured extensively in California. His poetry has been seen in Green Hills Literary Lantern, Orphic Lute, Third Estate's Quaranzine, and Freshwater Literary Journal. His poetic radio drama Hue can be heard online at Barewire Theatre Company. He recently retired from 35 years of teaching, including three decades as the head of the San Francisco State University playwrighting program, where he created multiple programs that gave thousands of students a place to find and raise their voices.
'“Who are you?” she cried, voice cracking and shrieking. “Where is the river, the night sky?"' Roy Conboy is a Latino/Irish/Indigenous writer and teacher whose poetic plays have been seen in the struggling black boxes on the edges of the mainstream theatre in Los Angeles, Santa Ana, San Francisco, San Antonio, Denver, and more; and whose musical plays for young people have toured extensively in California. His poetry has been seen in Green Hills Literary Lantern, Orphic Lute, Third Estate's Quaranzine, and Freshwater Literary Journal. His poetic radio drama Hue can be heard online at Barewire Theatre Company. He recently retired from 35 years of teaching, including three decades as the head of the San Francisco State University playwrighting program, where he created multiple programs that gave thousands of students a place to find and raise their voices.
Patrick Conboy comes on to talk about creative processes and finding inspiration through art. He is a filmmaker and most recently released his film called The Bug. Follow Patrick Conboy: https://www.instagram.com/ol_pat/ follow Brenden Pachniak: : https://www.instagram.com/brenden_pac/https://twitter.com/brendenpac
Abbot Charles ni jina maarufu kwa wanaoijua historia na wana zuoni, pengine umaarufu wa jina ndo sababu ya Baba yake kuamua kumpa mtoto wake wa kiume akitegemea na kijana wake atakua na ukubwa huo kwa lolote ambalo ataamua kufanya kwenye maisha yake, unaujua ule usemi kwa kiswahili kwamba maneno huumba? Mwenzangu, hata majina huumba, tena sana tu kwahiyo wakati mwengine utakapokua unafikiria jina la mwanao ni vyema kujiridhisha kwanza, unafanya kazi flani ya kipolisi ya kuchunguza ili mwanao asije akawa mtu fulani asiye na dira. Quick Rocka aka Switcher aka Baba aka Kaka Fule ni mdogo wangu, hizo aka alozojipa ni maana halisi ya uwezo wa kuishi kwenye kila character ambayo anayo na ameamua kuiishi. Ni Quick na anaweza kuku rock wakati ana rap, na anaweza ku switch na kuwa singer na mambo yakaenda vizuri tu, au aka switch na kuwa Kaka Fule, aka kufanya utake kuendelea kumuangalia tu kwenye Jua Kali au filamu ambazo amekua akifanya. Switcher pia ni producer mzuri tu wa muziki ambao anaufanya. Katika vijana wa kuwaangalia jinsi wanavyoelekea kwenye mafanikio yao yeye pia anafaa kuangaliwa na hii naamini inatoka kwenye kampani ambayo amekua nayo tokea siku ya kwanza alipojua anataka kufanya mziki, group aliyokua nayo kwenye Rockers ilikua imesheheni mafundi ambao pengine focus yao haikua kama ambayo Switcher amekua nayo au pengine walikua na vitu vyengine ambavyo ni vizuri pia vya kufanya na kuamua kuachana na muziki, pengine kufanya muziki haikua priority yao ila kwa Quick mambo yalikua tofauti. Ukaribu wake na Master Jay kwa kiasi kikubwa umemsaidia kuweza kuwa focused na mambo yake ya msingi na pia alikiri kwenye maongezi yetu haya kwamba kuna kipindi baada ya msiba wa Marehemu Kaka yake, alikua sehemu mbaya sana kifikra ila Master Jay alimsaidia kwa kiasi kikubwa kurudi kwenye mstari. Na kuanzia hapo sasa focus ya vitu ilianza kuwa 100% na ukiachana na kwamba Master Jay ndiye alimchomoa Quick kutoka kwenye kundi na kutaka asimame mwenyewe kama Solo Artist. Pia Marco Chali ndiye aliyekua anamtengezea muziki wake wote, na kamsoto flani ambako alikapitia ili kumfanye awe huyu ambaye yuko leo chini ya uangalizi wake kwa kiasi kikubwa pia yalimfanya asogee ki maisha, mambo yote ambayo tunakutana nayo kwenye njia ya kuelekea kwenye mafanikio ni lazima ilikua tuyapitie ili kutufanya tuwe bora kwenye haya maisha tunayoishi sasa. Ambacho hakiku uwi kinakufanya uwe jasiri tu. Na jasiri Quick alikua. Aliweza kufungua studio yake mwenyewe ambayo alimfanya awe huru zaidi na kujijenga zaidi, hapo studio pia alitoa nafasi kwa wenzake ambao nao pia walikua wanatafuta sehemu ya kutokea. Kwenye studio ya Switcher ndiko ambako OMG ya Salmin Swaggz, ConBoy na YoungLunya ilizaliwa, tuseme kwa Quick Rocka kuliwapa tafu ya kufika mjini. Ma producer mbali mbali pia walianzia pale na kupata nafasi ya kufanya mambo makubwa zaidi kwenye sehemu nyengine. Mimi na enjoy kumuona Abbot anavyokua na kujielewa na kujithamini, anavyo jibeba na kusogeza mambo yake kwa spidi nzuri. Kama kijana nna hakika ana mapungufu yake na kuna makosa alishawahi kufanya huko nyuma na probably hata mbeleni kwenye maisha, ila huwa hatumhukumu mtu kwa makosa aliyowahi kuyafanya bali kwa jinsi ambavyo alitoka kwenye hayo makosa na kuwa mtu bora zaidi. Yangu matumaini uta enjoy story hizi ambazo zilikua zinapigwa kwa uhuru wa iana yake. Love, Salama --- Support this podcast: https://anchor.fm/yahstonetown/support
GUEST OVERVIEW: Steve Conboy is Founder and President of M Fire Holdings LLC, operating as Mighty Fire Breaker. Under Steven's direction spanning a career of decades of Preventative Fire technology and chemistry, the organization has created proven property, raw material, and forest or vegetation protective systems receiving many third party accreditation and outstanding customer growth. Mighty Fire is a fire suppression company dedicated to serving homeowners, communities, Architects and reducing the risk of fire events affecting the Insurance industry and all stakeholders with an interest in saving property, human lives, mammals and reducing damage to the environment. At Mighty Fire Breaker It's our mission to protect property, the environment and communities from the costly or devastating effects and preventable damage from fires of any scale. The core of the Mighty Fire technology CITROTECH™ is Underwriters Laboratories, Greengard Gold Certified CitroTech has defended over 20 million square feet of structures to date and makes framing lumber Class A, when applied with an airless sprayer. CitroTech™ is plant-based, safe and effective for fire inhibition, without harmful effects to humans, animal life or vegetation or water supplies and protect structures, all building materials and even forests or mulch Mr. Conboy is author of a Carbon Tax Credit Bill and inventor of the most cost effective fire protection for framed wood structures which makes all Mass Timber safer in fire. M-Fire Holdings LLC supports all wood type structures, whether Stick Built or CLT for making buildings safer. With more than 40 years of experience in Raw Materials for the construction industry, advanced Research and Development of Proactive Fire Defense and multifaceted community protection development, Mighty Fire Breakers has amassed industry-leading, accredited and proven technology to now help improve fire safety in all industries and communities worldwide.
Watch out for the Vodcast with The Grand Theatre Operations Manager Shaun Gorringe and Theatre Photographer Sean Conboy . In this episode hear Sean and Shaun talk about the theatre photography workshops and the tours the Grand Theatre does for the community locally and from afar.Co-hosts, Ged Mills and Hayley Kay of local Breakfast radio fame, are back, and thrilled to be partnering with Blackpool Grand Theatre on a fantastic new Theatre Podcast (and Vodcast) Eat. THEATRE. Sleep. Repeat.Access Blackpool Grand's new theatre podcast Eat. THEATRE. Sleep. Repeat. hosted by breakfast radio legends Ged and Hayley, featuring everything from star interviews, theatre history, West End creatives, and world-renowned choreographers and puppeteers.Eat. THEATRE. Sleep. Repeat. will not only be available as a Podcast but as a Vodcast on a brand new YouTube channel at www.eattheatresleeprepeat.co.ukwith episodes accessible to its thousands of subscribers!Sign up today and access the latest theatre news, hear from award-winning artists and your local community groups, and of course, backstage exclusive gossip!Search nowEat THEATRE Sleep Repeaton your favourite podcast provider platform.
Watch out for the Vodcast with The Grand Theatre Operations Manager Shaun Gorringe and Theatre Photographer Sean Conboy . In this episode hear Sean and Shaun talk about the theatre photography workshops and the tours the Grand Theatre does for the community locally and from afar.Co-hosts, Ged Mills and Hayley Kay of local Breakfast radio fame, are back, and thrilled to be partnering with Blackpool Grand Theatre on a fantastic new Theatre Podcast (and Vodcast) Eat. THEATRE. Sleep. Repeat.Access Blackpool Grand's new theatre podcast Eat. THEATRE. Sleep. Repeat. hosted by breakfast radio legends Ged and Hayley, featuring everything from star interviews, theatre history, West End creatives, and world-renowned choreographers and puppeteers.Eat. THEATRE. Sleep. Repeat. will not only be available as a Podcast but as a Vodcast on a brand new YouTube channel at www.eattheatresleeprepeat.co.ukwith episodes accessible to its thousands of subscribers!Sign up today and access the latest theatre news, hear from award-winning artists and your local community groups, and of course, backstage exclusive gossip!Search nowEat THEATRE Sleep Repeaton your favourite podcast provider platform.
[*NOTE: Due to tech issues with Apple they couldn't resolve, we've had to take down and republish the episodes. Sorry for the inconvenience.] Trooper Mark Conboy, Kansas Highway Patrol, helped stop a multi-state crime spree that left five people dead and three critically wounded, including a deputy sheriff. His split-second decision to continue the pursuit, even though he was dangerously low on fuel, saved lives and brought an end to a violent rampage.Join us at Patreon.com/gameofcrimes for great content you won't hear anywhere elseDonate at paypal.me/gameofcrimes or go to paypal.com and use our email: gameofcrimespodcast@gmail.comGo to GameOfCrimesPodcast.com for more info and NEW MERCH!Follow us on...TwitterFacebookInstagramSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
[*NOTE: Due to tech issues with Apple they couldn't resolve, we've had to take down and republish the episodes. Sorry for the inconvenience.] Trooper Mark Conboy, Kansas Highway Patrol, helped stop a multi-state crime spree that left five people dead and three critically wounded, including a deputy sheriff. His split-second decision to continue the pursuit, even though he was dangerously low on fuel, saved lives and brought an end to a violent rampage.Join us at Patreon.com/gameofcrimes for great content you won't hear anywhere elseDonate at paypal.me/gameofcrimes or go to paypal.com and use our email: gameofcrimespodcast@gmail.comGo to GameOfCrimesPodcast.com for more info and NEW MERCH!Follow us on...TwitterFacebookInstagramSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Trooper Mark Conboy, Kansas Highway Patrol, helped stop a multi-state crime spree that left five people dead and three critically wounded, including a deputy sheriff. His split-second decision to continue the pursuit, even though he was dangerously low on fuel, saved lives and brought an end to a violent rampage.Join us at Patreon.com/gameofcrimes for great content you won't hear anywhere elseDonate at paypal.me/gameofcrimes or go to paypal.com and use our email: gameofcrimespodcast@gmail.comGo to GameOfCrimesPodcast.com for more info and NEW MERCH!Follow us on...TwitterFacebookInstagramSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Trooper Mark Conboy, Kansas Highway Patrol, helped stop a multi-state crime spree that left five people dead and three critically wounded, including a deputy sheriff. His split-second decision to continue the pursuit, even though he was dangerously low on fuel, saved lives and brought an end to a violent rampage.Join us at Patreon.com/gameofcrimes for great content you won't hear anywhere elseDonate at paypal.me/gameofcrimes or go to paypal.com and use our email: gameofcrimespodcast@gmail.comGo to GameOfCrimesPodcast.com for more info and NEW MERCH!Follow us on...TwitterFacebookInstagramSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
EfB skal have hentet 4 point på Fremad Amager i de sidste 4 kampe – hvis den også skal stå på 1.divisionsfodbold i næste sæson. Vi har taget en snak med EfBs rutinerede forsvarsspiller Kevin Conboy - om den opgave der nu venter – og med første kamp på søndag hjemme mod Vendsyssel.
My guests in today's episode are Dr. Irina and Michael Conboy of the Department of Bioengineering at the University of California Berkeley. Their groundbreaking research focuses on tissue rejuvenation via plasma dilution and heterochronic parabiosis, where the Conboys took a young mouse and an older mouse and sutured them together, such that the animals shared blood and environment. The old mice became rejuvenated & younger. They've also pioneered a process called the Neutral Blood Exchange or Therapeutic Blood Exchange, through which dilution of old blood plasma can lead to true rejuvenation in the brain & other tissues of mice to a younger state!! Further, we touch upon Irina's work showing how decreased Oxytocin levels with age contributes to poor muscle function. Their research is incredibly exciting and we discuss all about it in today's episode. Episode Show Notes: https://livelongerworld.substack.com/p/rejuvenation-via-plasma-dilution Sign up for Premium Subscriber Extensive Show Notes & Transcripts: https://www.livelongerworld.com/premium Find the previous podcast episodes & subscribe to be notified: https://www.livelongerworld.com/podcast DR. CONBOY LINKS: Berkeley Lab: https://conboylab.berkeley.edu/ 2021 Paper Plasma Dilution Improves Cognition and attenuates neuroinflammation in old mice: https://pubmed.ncbi.nlm.nih.gov/33191466/ 2020 Paper Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288913/ 2014 Paper Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration: https://www.nature.com/articles/ncomms5082 LIVE LONGER WORLD LINKS: Website: https://www.livelongerworld.com/ Twitter: https://twitter.com/livelongerworld Newsletter: https://livelongerworld.substack.com/ Instagram: https://www.instagram.com/longevityfuture/ Podcast All Platforms: https://anchor.fm/livelongerworld Patreon: https://www.patreon.com/livelongerworld YouTube: https://www.youtube.com/c/LiveLongerWorld Apple Podcasts: https://apple.co/3eZAoAp Spotify: https://spoti.fi/3eZB6O5 Google Podcasts: https://bit.ly/3HN0keG TIMESTAMPS: 00:00 Live Longer World Intro 00:35 Irina & Michael Conboy Intro 1:08 Aging is slowdown in our repair machinery 2:55 Naked Mole Rats not extreme model for longevity 5:37 Heterochronic Parabiosis 16:00 Young Blood to Old Blood Exchange 19:19 Rejuvenation via Neutral Blood Exchange (NBE) 22:56 Old Blood Degenerates Young Mice 25:29 Rejuvenation Effects on Brain, Liver, Muscle through NBE 27:16 How long do effects of NBE last? 30:15 How is NBE working mechanistically? 2 waves of rejuvenation 33:38 Inhibiting TGF-beta & Increasing Oxytocin is rejuvenative 38:12 NBE vs. Senolytics 40:53 Unanswered Questions on NBE 43:13 Oxytocin & Muscle Functioning; Notch Signaling 48:12 Chickens & Ravens as Pets! Thanks for listening & if you enjoy the episode, please like, subscribe & share! Stay in good health - Aastha.
Hør denne uges podcast ”Vi taler om EfB”, hvor JydskeVestkystens Ole Bruun fortæller om, hvorfor man ikke skal overvurdere præstationen i storsejren i Hobro, EfB's spillere ikke får lov til at miste jordforbindelsen og hvorfor det bør ende med en hjemmesejr over Jammerbugt FC. Studievært: Chris Uldahl Pedersen
This week we hear from Sean Conboy, Executive Editor at The Players' Tribune; a sports-focused site that publishes first-person stories from professional athletes. He talks about the process they use to get content from elite athletes, and why the site doesn't shy away from difficult stories and human rights issues, like the ones around the Qatar World Cup. In the news roundup Chris and Peter take a look at a grab bag of media stories from the Financial Times reporting a loss, through the reinvention of Rolling Stone, to the hypocritical hiring practices of the BBC's director general. Video podcasting killed the podcasting stars.
The original broadcast date for this episode of the Leadership Under Fire Optimizing Human Performance Podcast was January 10, 2019. In 2018, Lieutenant Conboy was recognized with the FDNY's highest annual award (James Gordon Bennett) for valor he displayed in the rescue of occupants at a fire in the South Bronx. He recently received the FDNY's most prestigious award for valor – the Dr. Harry Archer Medal. Lieutenant Conboy has more than 35 years with the FDNY. He is presently assigned to Rescue Co. 3 in the Bronx and previously served as a Lieutenant in Squad Co. 41 and a firefighter in Engine Co. 79, Ladder Co. 37 and Rescue Co. 3. Lieutenant Conboy is an Adjunct Instructor at the FDNY Fire Academy and the FDNY's Technical Rescue School. He was instrumental in the development of the course curriculum for Advanced Firefighter Victim Removal training for FDNY Special Operations Command firefighters and officers. External recognition aside, he's also experienced quiet moments of accomplishment and fulfillment in the fire service and in his personal life as a father and grandfather.
Can we stave off the aging process by transfusing young blood into old people? The idea that youthful blood might have rejuvenating properties has lingered in popular imagination for centuries. In this episode of humanOS Radio, Dan speaks with Drs. Michael and Irina Conboy of the Department of Engineering at UC Berkeley. Their lab investigates the process of tissue repair throughout the body, and is trying to determine why damaged tissue is not productively repaired as the body ages.