Podcasts about new treatments

Episode 316 hosts Meg McNeil (Director & Registered Nurse from Brisbane, Australia) & Bek McNeil (Director & Business Manager from Brisbane, Australia) In 'The Business of Injecting' episodes we host injectors and clinic owners to discuss all aspects of the business side of their clinic. We analyse their financial struggles and challenges, difficult decisions, friction points, staffing, hiring, firing and other topics relevant for aesthetic business owners. In Chapter 20 we discuss the success, challenges and future with two of the founders of Derm Haus. Our guests discuss their journey into the aesthetics industry, starting as a side hustle and growing it into a thriving business with two clinic locations and a team of 11.  They share how they created a supportive work culture, handling the financials and logistics of a growing business, and the importance of using each team member's strengths. We also cover their strategies for marketing, patient retention, and the impact of word-of-mouth referrals. Our discussion wraps with insights into future plans for Derm Haus, including a focus on women's health and regenerative medicine, and the challenges of maintaining a successful business in a rapidly changing industry.  00:00 Introduction 01:20 Business of Injecting: Episode Overview 02:26 Meet the Derm Haus Team 03:38 Starting the Business: Challenges and Growth 10:20 Bringing Bek Onboard  17:46 Client Selection and Business Strategies 20:42 Managing Stock and Team Consistency 26:59 Creating an Employee-Centric Workplace 28:05 Deciding on New Treatments and Devices 32:05 Pricing Strategies and Financial Management 37:15 Staff Retention and Incentives  41:09 Marketing and Brand Strategy 45:08 Future Plans and Business Growth  49:26 Reflecting on the Journey and Final Thoughts SUBSCRIBE TO OUR PATREON FOR EXCLUSIVE PODCASTS, WEEKLY EDUCATIONAL CONTENT & JOIN OUR WHATSAPP COMMUNITY CLICK HERE TO BROWSE OUR IA OFFERS FOR DISCOUNTS & SPECIALS CLICK HERE IF YOU'RE A BRAND OR COMPANY & WANT TO WORK WITH US CLICK HERE TO APPLY TO BE A GUEST ON OUR PODCAST CONTACT US

The rationale, design, and mechanism of GABA aminotransferase and ornithine aminotransferase inactivators will be presented as well as in vitro and in vivo efficacy and pharmacokinetic results, toxicology studies, and a clinical trial with one of the inactivators.

Welcome back to the Oncology Brothers podcast! In this episode, we continue the three-part CME series on small cell lung cancer, focusing on adverse events and management strategies for extensive stage small cell lung cancer treatments. We are thrilled to have Dr. Misty Shields from the Indiana University join us to discuss the latest advancements in treatment options following the exciting data presented at ASCO 2025. We dived into the treatment algorithm for patients with good performance status, including the use of chemoimmunotherapy, lurbinectedin, and tarlatamab. Key topics covered in this episode: •⁠  ⁠Overview of the current treatment landscape and new data from ASCO 2025 •⁠  ⁠Common side effects associated with lurbinectedin and immunotherapy •⁠  ⁠Strategies for managing adverse events, including hematologic toxicities and liver function monitoring •⁠  ⁠The role of supportive care and palliative care in enhancing patient quality of life •⁠  ⁠Collaboration between community oncologists and academic centers for optimal patient care Join us as we explore the challenges and opportunities in managing extensive stage small cell lung cancer, and learn how to provide the best care for patients facing this devastating disease. Accreditation/Credit Designation Physicians' Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Physicians' Education Resource®, LLC designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Acknowledgment of Commercial Support This activity is supported by an educational grant from Jazz Pharmaceuticals, Inc. Link to gain CME credits from this activity: https://www.gotoper.com/courses/practical-considerations-and-future-directions-for-new-treatment-strategies-in-sclc Follow us on social media: •⁠  ⁠X/Twitter: https://twitter.com/oncbrothers •⁠  ⁠Instagram: https://www.instagram.com/oncbrothers •⁠  Website: https://oncbrothers.com/ #SCLCtoxicity #Lurbinectedin #Tarlatamab #SupportiveOncology #CMEoncology

Dr Bill Nelson and Dr Michael Pishvaian discuss the targeting of KRAS mutations in pancreatic cancer to develop new treatment options for a disease that has been historically difficult to care for.

Kristy and Tiff discuss the new treatments they're seeing practices adopt these days and how to successfully start the process (if you want to). They touch on the best ways to gauge interest, training and implementation tips to start off, how to track results, and more. Episode resources: Subscribe to The Dental A-Team podcast Schedule a Practice Assessment Leave us a review Transcript The Dental A Team (00:01) Hello, Dental A Team listeners. We are so happy to be back here with you. We are recording today from the comfort of our own homes with the ACs blasting. I am about to bust out my fan. is on the charger right now. I don't know if you know this or not, but Kristy and I come to you from the sweltering desert of Phoenix, Arizona. And I have to say, I'm crazy. My boyfriend is like, it is hot. We're getting out of here. We're moving to Prescott. And one day I'm sure we will, but.   I love where I live and every time I go travel to an office and I'm gone for like a week, I'll see two, three offices at a time. I come back in and just coming into Tempe on that plane over in the mountains, you can see the Buttes, you can see South Mountain, you can see the city and just like the buzz of it all makes me so incredibly happy every single time. I love where I live. I cannot at this point in my life imagine living anywhere else. So when I say that out loud,   People think I'm crazy. And I'm like, listen, it's beautiful here. My best friend, bless her heart, she's like, Tiff, it's brown. It's all desert. And I'm like, it's not. Do you see these colors, like the saguaros and the pink flowers that bloom and the yellows? And like, I don't know, Kristy, am I crazy? Or what are your thoughts? You came back to Arizona. So obviously, there's something to be told about that.   DAT Kristy (01:25) It's too funny that you say that because it's so true. I'm you know when I moved to Idaho everybody's like Arizona it's a desert and I'm like but there's desert here. I have to agree the Arizona desert is much prettier. ⁓ Southwestern Idaho is very deserty and we're talking brown. There's where the brown is but Arizona desert is very beautiful. Even this time of year like come on Palo Verde's aren't brown they're green.   The Dental A Team (01:35) Yeah.   Yeah.   Bye.   Right? Literally   in their name, right? Palo Verde. My boyfriend always says, yeah, Arizona is like so inventive, the green stick. And I'm like, well, it's green. It is green, okay? That's our state tree and it's green. Yeah, I agree. I agree. I just think it's beautiful. And there's nothing like a desert rain. I know that sounds so cliche. Everyone says it, everyone hears it, but I swear to you, the smell in the desert after a good rain or even a light sprinkling is magical.   There is something about it that just changes the composition of your body and you become a much happier individual. just, can't be, you can't be angry in the desert rain. So.   DAT Kristy (02:33) agree with you Tiff   and if you and I can figure out a way to bottle that stuff I've always said we'd be millionaires.   The Dental A Team (02:39) Yeah, well, you know,   I just, my friend just told me this a couple months ago. There's actually a bush out there. I need to just take a picture of it and figure out what it is. We were hiking one day. There's a bush out there that you, when you pick the leaf and you like put it between your fingers, it smells like the desert rain. I'll find it. Yeah, I'll find it and take a picture. I don't know what the bush is, but I'll find it and take a picture and Google it so that we can, we could bottle it. My point there. Yeah. I actually had a friend in town.   DAT Kristy (03:02) Yeah.   The Dental A Team (03:06) Um, he lives in North Carolina and he was visiting and he was like, I'm taking some of this home so that other people can smell it. Cause it is incredible. And I'm like, yep, that's what Arizona desert rain smells like. So anyways, everybody who wants to come visit, we are here for it. We aren't taking any new visitors like to stay. I'm just kidding. You can move here. It's just, it's just getting crowded, you know, but visitors are welcome. Come.   share in the heat. I know most people come in the month of February for the Waste Management Open and you just let us know when we're here and Kristy and I will pop over and say a little hello to you. So Kristy, getting on to business, I love talking about Arizona and I would do it forever, ⁓ but we're kind of rounding out the year right now. We're heading into quarter four. This is the time of year I'm like, well,   we can still make massive movements, we can still make massive changes and hit those goals, but really we need to start thinking about what are we doing ⁓ after these goals are hit. So lot of people don't think about the next year, which is 2026 until December, but I'd like to start talking about it here in August. So one of those pieces, Kristy, I really wanted to chat today about offices that we've seen implement new treatment. And I know right now, ⁓ fillers, Botox, I've seen   a ton of practices doing like facial aesthetics and the lasers and I don't even know what they're called the ones and like all of these amazing things and takes me back to when I was ⁓ working in office gosh when I first started I was like 19 and my doctor's like where are those paraffin wax things can we get those and I was like you're crazy we are not a spa like we're not doing paraffin wax for our patients I have enough to do   chair side, have enough to clean up, we're not doing this, right? But he really wanted it and so we did at least, we did warm towels. So it's like, I can handle warm towels, it's all you got. But now, there is really like this spa aesthetic feel to a lot of dental practices. And I know there's plenty of us out there that are like, no, not doing that. I am a dig my heels in kind of girl. So I dig my heels in until the very end. But I'm kind of getting on board with it. I kind of like it. And it's adding a different sense and a different value.   And honestly, I love marketing and it's adding a different marketing avenue because it's a different demographic of people who can come for the aesthetic side and see, I love these people. Let me switch my dental as well. They may not, that's okay. They may love their dentist. But if you can come to one place and get multiple things, that's kind of cool. So, Kristy, I just wanted to chat a little bit about some of the things that we've seen. We've worked, you guys, just so you know, we worked with a ton of practices on adding aesthetics.   Botox fillers, ⁓ implants, just like simple single tooth implants, multi-tooth implants, all on fours. Gosh, what else? Orthodontics, making sure that the marketing is there, making sure that the treatment coordinating aspect is there, making sure that case acceptance is working, the schedule is working, the block scheduling. We have helped implement this in so many practices. So as we're talking today, just know we're speaking from that implementation experience and what we've seen really work for practices.   from our experience working one-on-one with doctors. If you're someone who's looking to implement new products or new services in your practice and you're not really sure on the how-to, please reach out. We would love to help you on a one-on-one basis. Hello@TheDentalATeam.com. Again, we have a ton of experience in this. have five experienced consultants ready to work one-on-one with you. ⁓ Kristy, Monica, and Trish are...   freaking incredible you guys. I have just seen them move mountains for clients in very short amount of time. if you are ready to take that step, let us know. Hello@TheDentalATeam.com. But Kristy, I know you've had a lot of clients. You've actually had, you've had some fun clients that I can think of off the top of my head that are kind of fresh and new and starting out. And I know one in particular I can think.   probably is this like go-getter wants to add everything, wants to take all the CE, wants to implement everything and wants to just run with it. And then you've got some others that are like, I'm going to like take my time. I'm going to buy it my time. I'm to take the CE. Maybe in a couple of years, we'll be able to implement it. Like there's like such drastic differences there, but what kind of ⁓ procedures have you seen implemented recently? And what do you feel like your clients are doing really well?   to implement them within their practice with your support.   DAT Kristy (07:45) Well.   like you, the med spa thing has really taken off in dentistry. So adding in the Botox, the laser ⁓ and sleep, even for little kiddos, the tongue ties has been an area of exploration. with that being said, Tiff, think first and foremost, yes, you're right. I have one client that's kind of a go getter and and honestly him bringing the energy has worked really well for him because his excitement is   driving it, right? But one thing that I would say in the very beginning, if you're exploring this and you aren't that go getter, energetic, I'm going to do this attitude and you're kind of thinking about it, start to take a pulse with your patients. know, explore, hey, if we offered this service, is this something you'd be interested in? See if people are interested in it because you may be leaving room on the table, right?   And maybe you'll find out they're not interested and it will drive you in a different direction But with that being said, like I said take a pulse of your own patients, but I also doctors recommend that you ⁓ Get your admin team ⁓ Keeping a list of things that patients are calling in and asking for and they have to say no we don't do that because that's an area of opportunity that perhaps if you have a hundred people calling and asking   The Dental A Team (09:10) That's a great idea.   Yeah.   That's a great idea. I have never in my life thought of that. That's beautiful. I love that you said to ask the patients themselves as well. If I started offering this, is this something you'd be interested in? And that one's kind of an easy one when it comes to like Botox and things like that, because you can tell when someone has utilized that procedure before. So I've even had doctors say, where are you going for your Botox? Like, do you like where you go? Are you happy there? What are they doing well that keeps you coming back? even as far   is   to ask what they're paying because it really helps them to figure out.   how they can generate that within their own practice based on a scale of like, know, chatting with a couple of different patients, because you really can tell fillers as well. And all of that stuff, you guys, to be redone at some point. So I think that's a great idea. apnea is huge. I think the kiddo stuff is massive. I have a couple of doctors, couple of doctors, but then also I have a GP doctor that does a ton within the lip tie, the sleep apnea, all of those pieces for the toddlers and children.   She's so passionate about it that her team is behind her as well on it. So I think that's a really good point. And I think, Kristy, something you touched on was that passion and how excited that specific doctor we're thinking of is about everything he does, everything he does he's excited for. And so I just feel like walking into his practice, you're just amped up. Like the energy's got to be so high. But for...   everyone no matter what anytime you go take a CE, anytime you have an idea, anytime you're like I want to implement this and you go get trained on it, I think the biggest missing piece that I've always seen myself as a consultant and then myself even as a dental assistant or for an office is that information lapse between you taking the course and coming back with the information and that ⁓   I get from a business standpoint and a doctor's standpoint, it's hard to take your team to the CE with you. And sometimes it's not even offered to bring your team. So I get that, but that's where training comes into play. And I think that's where having someone on your side, a coach and a consultant, someone who's working hand in hand with the team who really can help create protocols, who can help with the verbiage because you're over there implementing. And I don't know, Kristy, if you've ever experienced this, I remember my doctor, he would get so deflated.   because he'd go do this thing, he'd be rammed up sleep. He wanted to sleep so badly and I hope to this day that he's doing it, but it was so difficult and we didn't get the training, we didn't get the courses, he was training us which was great, but it was like also we are doing everything we were doing before you took this course. So the space for me to learn how to add this, for me to take the time out of my day,   to implement this just isn't always there. And so the space to do the training is sometimes lacking if you can't take your team with you. So I know I've got a practice that I've helped a ton with sleep just in general at their practice because they needed the protocols put in place, but they didn't have the time to even sit down and type them. So it was like,   We're going to do this together real quick. Our tips got these ideas. We've got templates that we utilize with our clients that we're like, hey, these are my ideas. And we go back and forth. And we figure out what's working, what's not working. And Kristy, I know you've done that too. What have you seen work really well with practices for that training and implementation?   DAT Kristy (12:57) It's kind of funny because the ways you're talking I'm thinking of a client right now that literally just went she did take her team to Vegas for clear liner course and Thank goodness. were blessed to go right because you're you're right getting the whole team behind them and the energy coming back in is huge the energy really does propel the momentum as you're Trying to ramp up and to your point not everybody can take the whole team So so I get that yet if you can get one or two chances   to go and help you wonderful. If not, would definitely recommend coming back and having the conversation and have doctors speak to their why. You know, why do they want to implement this? What is their vision for it? And then create benchmarks. Like how will we implement this and what can we do? So if we want to do more clear aligners, what is   The Dental A Team (13:37) Yeah.   video.   DAT Kristy (13:56) something we can do every day to help that outcome, right? Is it add one more scan to a patient? You know, get those commitments from team and buy in and then have fun with it. We're always talking about the sprinkles and adding the fun. So find a way to gamify it. And if I do this action every day, it's going to create a better chance of my outcome, right?   The Dental A Team (14:00) Yeah.   Mm-hmm.   Yeah,   yeah, and to that point, you're then tracking your results, right? Which is something that we have all of our practices tracking their results consistently for that reason, because we want to see the things that you're doing every day. Are they creating the result that you wanted? Are we moving closer to the goal that you were set after? Or are we moving further away from it? Because then we can see what we want to tweak or change or what needs to be added. And then again, to your point as well, what's one thing that we can add?   A lot of times we come in with all of the things and it's like, that's too much and we can't process it all. So if you do that, like one thing, so for sleep apnea or Botox or any of those spaces or though it's like, what's one thing you would change aesthetically if you had the opportunity? Like what's one question? You can start asking every patient that walks through your door. Do you find yourself waking up a lot at night? Do you find yourself, know, do your partner say that you're snoring?   Do you have a hard time falling asleep? Do you have a hard time waking up? What are the key factors? What's one question, two questions you add onto it? How can we layer this and stack to get things done? And like you said, maybe we're taking one more scan today than we took yesterday. We're gamifying it, we're tracking the results, and we're making sure that it's fitting. And that's something that I think as consultants, we've been able to really help teams get excited about.   and really be able to help them break it down because for doctors, for our visionaries, it's sometimes difficult for a visionary to see the path. They see the end result. They see what it is that they're after. They see the dream and the finality. We have to take it layers backwards and say, how do we get there?   The visionaries have a hard time figuring out how we're going to get there. And when they're the only ones who are trying to figure that out or there's no one on the team that's like, okay, I got it. I will figure it out from here. That's where the consultants come into play or training office managers to see that space to say, okay, what are the steps it's going to take to get there? And how do we incrementally layer and add onto those steps to ensure that we do? So, Kristy, I think you're hitting some massive spaces there.   with the tracking the results, the just one thing and making sure that we are training the team as we can. I also think don't wait too long.   If you've gone to a course and you've learned something, you need to start practicing it because you learned it. And then if you're waiting a year to implement it, you're going to need to go back for a refresher course because you haven't been doing it. And I've seen that happen. I don't know if you have. I've seen that happen, especially with like Botox, where they go get the training, but they're just like dragging their feet, probably out of fear and actually implementing it. And then they're like, well, shoot, I need to go get a refresher course because I haven't done it since I did it at   my training. Have you seen that too, Kristy?   DAT Kristy (17:27) Absolutely.   I love that you mentioned that because I think one realm where we're really good at this if you think about it is ⁓ Milling same-day crowns because they force you to find patients, right? They're like, okay have your patients lined up because we're gonna do it in those other realms We don't necessarily do that. So a component that I think we miss a lot is we plan the CE we schedule it we go the course But we didn't block out time to meet with team coming back, right?   The Dental A Team (17:36) Yeah. ⁓   Yeah.   DAT Kristy (17:57) So make sure that time dedicate the time to make sure it happens and Hey, let's line up the patients. Let's get them in the chair and start because you're right Otherwise, we just get back into routine and it's gone to the wayside and you know See is wonderful and it's all knowledge. But unless we're interpreting it into something It's just money spent right? Yeah   The Dental A Team (18:22) Agreed. Yeah, agreed.   And it makes me think of two of ⁓   Like you said, they tell you to have patients ready for the crowns, but same thing for implants, right? Same thing for Botox, same thing for any of those, but implants especially. I always tell doctors, before you go to the course, I say take inventory, look at how many outgoing referrals you had to oral surgeons. How much revenue did you feed oral surgeons in your area of that thing that you're going for? Because they have had practices in areas of their city   that it was like it didn't make sense financially to implement the thing because they weren't getting it in their doors, right? They were a younger demographic, they were college demographic, and they really just weren't getting a lot of need for the implants or for whatever it was that they were looking at. And so they actually decided, you know what, like that was just, there's so much that we see that we're supposed to do. ⁓   like all on four, all on X. Like there's so many GP dentists that are like, well, I just felt like I heard that that was what was going to change my life forever. And I'm like, yes, in a lot of ways, it's really hard. So don't do things just because it's what you're supposed to do. And it's like the next best up and coming thing. Cause I have seen doctors who have taken inventory and they're like, actually, like I was going to do it because I thought I needed to, but I don't think my patient demographic shows me that I need to. I may actually focus   in on this and they switched their CE focus completely because they saw the need wasn't there and for me that's massive because now you're you are getting an ROI on what you're doing. Now for a lot of dentists they want to learn the thing because they want to know it and that's totally cool. don't I don't I have no ifs, ands, or buts about it but just make sure you know what you're getting into and then like Kristy just said I love that idea of making sure you've got people lined up to get the service.   once you come back. And it's an easy conversation. It's not, I'm going to go get trained on implants. And so when I come back, I'd love for you to be one of the first people I place an implant on. That's uncomfortable, right? But it's just like, hey, I don't have the tools for this right this second. ⁓ You can go to an oral surgeon if you want it sooner, but I am going to be equipped with those tools here in the next six months. I'd be happy to revisit this with you at your next re-care or call you as soon as I get the stuff in.   Same statement, different words. so vulnerability on one hand. If it's family, like shoot, I've had plenty of doctors that's like, hey, I'm testing this on you and you're getting it for free. Or I'm testing it on you and you're gonna pay for the lab fee, like fine.   whatever, but patients maybe be a little bit more tactful with. But Kristy, I think those were some great points. Those are all wonderful things that I've seen you help doctors implement. I've seen Dana, Kristy, or Trish. I've seen all of you guys. Monica, know she's done it too. We've all implemented on some level some of these systems and protocols with practices for things that feel really hard when you're in it. The great part about consultants,   I'm not attached to it, you guys. Kristy's not attached to it. We're attached to you seeing results and we're going to bird's eye view it and see where the missteps are happening, where the gaps are that can be filled to create a different result because Kristy's not emotionally attached to it. So they do really, really well. Kristy, Trish, Monica, Dana, all of them do really well at being able to see those gaps and see how you as a team can fill them and then train you guys on how to fill them. Our job is not to do   it for you because then I'm not teaching you anything, right? Kristy is not, she becomes your regional manager and that's not what we signed up for. But what her job is to do is to show you the path, train you how to do it, watch those benefits, you reap those benefits at the end. So we're excited to help you guys. Kristy, I know you're excited. You love implementing and Kristy loves nothing more than finding the money, finding the money, finding the production and helping you implement structures that really work to make a difference in your practice.   Kristy, thank you for your words of wisdom today. Those were fantastic. think my biggest nugget today is the idea of duh.   have people lined up and ready to go for whatever it is prior to you ever going and getting the course. And I think as I say that, Kristy, there's a lot of protocols and a lot of training that can be done prior to the CE to get your team ready too. Because otherwise the team's just upside down trying to figure it out. But those protocols and things can be put into place before you actually get trained to place and plan. So Kristy, thank you for being here with me today. ⁓   Everyone, I hope you took some solid nuggets from this and you can see how beneficial this can be. Drop us a five star review below. We'd love to help you. Hello@TheDentalATeam.com. We can't wait to hear from you guys. Thanks.  

For more information regarding this CME/CE activity and to complete the CME/CE requirements and claim credit for this activity, visit:https://www.mycme.com/courses/personalizing-care-identifying-the-right-patients-for-new-treatments-10268SummaryDr. Genevieve Neal-Perry and Dr. Andrea Singer focus on practical strategies in the personalized management of menopausal vasomotor symptoms (VMS). The discussion covers the importance of routine and individualized screening for VMS, with attention to healthcare disparities and the diverse ways menopause is discussed and experienced across populations, before covering patient selection criteria for newer non-hormonal treatments.This podcast was recorded and is being used with permission of the presenters.Learning ObjectivesIntegrate routine and individualized screening methods to identify patients with menopausal VMS, with attention to healthcare disparitiesIntegrate new and emerging agents into the treatment of women with menopausal VMS, based on patient characteristics and preferenceThis activity is accredited for CME/CE CreditThe National Association for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.The National Association for Continuing Education designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.The National Association for Continuing Education is accredited by the American Association of Nurse Practitioners as an approved provider of nurse practitioner continuing education. Provider number: 121222. This activity is approved for 0.25 contact hours (which includes 0 hours of pharmacology).For additional information about the accreditation of this program, please contact NACE at info@naceonline.com.Summary of Individual DisclosuresPlease review faculty and planner disclosures here.Disclosure of Commercial SupportThis educational activity is supported in part by an educational grant from Bayer HealthCare Pharmaceuticals Inc.Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

With BCG in short supply and recurrence rates still high, the race is on for better intravesical options. In this episode of BackTable Tumor Board, Dr. Lindsey Herrel, urologic oncologist at the University of Michigan, joins Dr. Ruchika Talwar to explore the evolving landscape of intravesical therapy for intermediate risk bladder cancer. --- This podcast is supported by an educational grant from UroGen Pharma. --- SYNPOSIS The doctors break down the nuances of defining this risk category and the clinical gray zones that complicate treatment decisions. Dr. Herrell shares her patient-centered approach to surveillance and therapy, and introduces promising new agents, including Anktiva, UGN-102, and the gemcitabine-releasing TAR-200 "pretzel" device. The discussion also highlights how advances in molecular profiling are reshaping care strategies.This episode underscores the urgent need for clearer guidelines and continued innovation to improve outcomes and quality of life for patients with this nuanced disease subtype. --- TIMESTAMPS 00:00 - Introduction02:03 - Defining Intermediate Risk Bladder Cancer06:12 - Intravesical Therapy Options08:47 - Quality of Life and Patient Counseling10:18 - New Treatments on the Horizon12:56 - Practical Tips for TURBT Recovery17:03 - In-Office Procedure Management21:38 - Managing Symptoms and Quality of Life31:50 - A Note on Smoking Cessation33:37 - Conclusion and Future Directions

Dr. Mitch Shulman can be heard every weekday morning at 7:50 on The Andrew Carter Morning Show.

In this episode of the Cancer Assist Podcast, Dr. Bill Evans sits down with Dr. Peter Ellis, medical oncologist at the Juravinski Cancer Centre, to talk about the incredible changes in lung cancer care. Once considered one of the most hopeless diagnoses, lung cancer treatment has drastically changed, with targeted therapies, immunotherapy, and personalized care offering patients more options and longer lives than ever before. Dr. Ellis shares what patients need to know about diagnosis, treatment choices, and why there's real reason to feel hopeful.----DisclaimerThe Cancer Assist Show is hosted by Dr. Bill Evans, MD, FRCP, Past President of the Juravinski Hospital and Cancer Centre at HHS. Brought to you by the Cancer Assistance Program—an organization lending support to cancer patients and families of those affected by cancer. --- The Cancer Assist Show and its content represent the opinions of Dr. Bill Evans and guests to the podcast. Any views and opinions expressed by Dr. Bill Evans and guests are their own and do not represent those of their places of work. The content of The Cancer Assist Show is provided for informational, educational and entertainment purposes only, and is not intended as professional medical, legal or any other advice, or as a substitute or replacement for any such advice. The Cancer Assist Program, Dr. Bill Evans and guests make no representations or warranties with respect to the accuracy or validity of any information or content offered or provided by The Cancer Assist Show. For any medical needs or concerns, please consult a qualified medical professional. No part of The Cancer Assist Show or its content is intended to establish a doctor-patient or any other professional relationship. This podcast is owned and produced by the Cancer Assistance Program.

Dr. Theodore Henderson is an MD. PhD, Founder, CEO and Medical Director of Neuro-Luminance, who brings decades of clinical experience in psychopharmacology, neurobiology, infrared light therapy, and neuroimaging to the successful treatment of brain disorders.   Dr. Henderson and his team specialize in treating patients with depression, concussion, brain injury, PTSD, Chronic Fatigue Syndrome, Parkinson's Alzheimer's, and ADHD. He is also the author of the recently published book titled “Brighter Days Ahead: Leaving Depression Behind Through Innovative New Treatments” which is an excellent and easily readable introduction for people of every walk of life to understand the concepts as well as the benefits and healing power of infrared light therapy.  In this informative, positive, hopeful, and also entertaining episode, Dr, Henderson skillfully explains exactly how the brain changes as a result of depression, traumatic brain injury, Long COVID, chronic fatigue syndrome, and other brain disorders. He describes the revolutionary new treatments that activate the brain's own ability to repair itself. He has a knack for describing complex brain conditions and neurological function in great detail and in terms that are easy to understand, and he does it with a sense of humor as well.   Download this fascinating episode to hear Dr. Henderson's story and discover how these groundbreaking new treatments can give hope and healing to people suffering from brain disorders and neurological dysfunction, and please share this positive message of hope and healing with your friends, family, and anyone you know who can benefit from this remarkable technology.   Connect with Dr. Henderson: https://neuro-luminance.com/ https://www.facebook.com/LuminanceBrainHealth https://x.com/neuroluminance?lang=en&mx=2 https://www.youtube.com/@NeuroLuminance?app=desktop https://www.linkedin.com/in/theodore-henderson-md-phd-98201318/ https://www.youtube.com/watch?v=zdFstQSR_A4

In this episode of The Egg Whisperer Show, Dr. Jenna Turocy is joining me to talk about new treatment options for recurrent implantation failure. Recurrent implantation failure (RIF) is determined when embryos of good quality fail to implant following several in vitro fertilization (IVF) treatment cycles. The good news is that there is treatment for this, and Dr. Turocy has been researching it. The types of treatments that Dr. Jenna has studied include:

Mandy talks about how expensive it is to replace the Ford F-150 Lightning truck battery is, she spoke with a young man with a fatal disease who is advocating for Right to Try new meds, Rich Guggenheim with Gays Against Groomers pops on for an update, Hamas wants Palestinians to starve rather than take aid from a group that MAY be associated with Israel, and the Plum Creek Garden Market team visited to talk about glow in the dark petunias. 

Dr. Andreas Walther is a senior researcher for science and teaching at the Department of Clinical Psychology and Psychotherapy of the University of Zurich and clinical psychotherapist with the outpatient clinic for Cognitive Behavioral Therapy and Behavioral Medicine of the Psychotherapeutic Centre of the University of Zurich. Andreas discussed the journey to his work focused on developing a treatment for men experiencing masculine or masked depression. He mentioned his father's struggle with depression and a serendipitous meeting with a graduate school advisor who needed a student to conduct research on men. Andreas' initial work was focused more on the effects of testosterone on mood in men, but increasingly his work led him to also integrate the investigation of masculinities into his research. He is currently conducting a clinical trial that involves the investigation of gendered depression in men. We discussed what this treatment looks like compared to a standard treatment for depression.   D83

There's a care model for schizophrenia that actually works—why isn't it everywhere? On this episode, W. Gordon Frankle, MD, MBA, Vice Chair of Psychiatry at NYU Langone Health, shares how his team in Brooklyn is building a new model for treating serious mental illness—one rooted in long-term, relationship-driven, team-based care. From wraparound services to precision psychiatry, this conversation explores what happens when you bring humanity, structure, and innovation to a population too often left behind.Also discussed:The first novel schizophrenia drug in over 50 years (Cobenfy)Why clozapine is underused—and how that may finally changeThe potential of brain imaging and biomarkers in psychiatric treatmentWhat a real community mental health system looks likeWhy trust, not just treatment, is essential for recovery

TODAY ON THE ROBERT SCOTT BELL SHOW: Universe 25 Experiment, David Rasnick, Kala Mandrake, Caltha Palustris, Realtime Vax Injury Tracking, New Treatments for Measles, Gold for Groceries, Bayer Glyphosate Immunity, Real Dino-Skin Purses, Question of the Day, and MORE! https://robertscottbell.com/universe-25-experiment-david-rasnick-caltha-palustris-digital-vax-injury-tracking-new-treatments-for-measles-gold-for-groceries-bayer-seeks-glyphosate-immunity-real-dino-skin-purses-question/

TakeawaysMASH is a significant obesity-related complication.Semaglutide shows promise in treating MASH.Weight loss is crucial for improving liver health.Bariatric surgery remains the most effective treatment.The Essence trial indicates a 63% resolution of NASH.New medications are being developed for obesity treatment.Early intervention is key to preventing severe liver damage.Accessibility of medications is a major concern.Comparative studies are essential for evaluating new treatments.Future treatments may include innovative delivery methods.Chapters00:00 Introduction to MASH and Semaglutide Study04:29 Understanding Metabolic Dysfunction and Its Implications08:02 Essence Trial: Semaglutide's Impact on MASH12:58 Comparative Analysis of New Treatments for MASH17:30 The Future of Obesity Treatment and Drug AccessibilityJoin Vineyard - Dr. Spencer's online clinicSee the study

In this episode, Monique Blanchard, a Clinical Nurse Consultant in Radiation Oncology at Austin Health in Melbourne, poses a series of questions to Associate Professor Sweet Ping Ng and Dr Ee Sian Choong, Radiation Oncologists also from the Austin Radiation Oncology Centre, Melbourne. You'll learn about the significant advancements in improving imaging and radiation delivery techniques, including improvements in delivery design and stereotactic radiotherapy; how these new techniques are improving patient experiences; and the challenges and future of radiation oncology.

Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma and Biotech world.##Title: Pfizer and BioNTech seek FDA approval for COVID-19 vaccine boosterPfizer and BioNTech have announced that they are seeking authorization from the FDA for a booster dose of their COVID-19 vaccine. The companies have presented data showing that a third dose of the vaccine can significantly increase protection against the Delta variant.##Title: Moderna to supply 100 million more doses of COVID-19 vaccine to the USModerna has reached an agreement with the US government to supply an additional 100 million doses of its COVID-19 vaccine. The company will deliver the doses by the end of the year, helping to boost vaccination efforts across the country.##Title: AstraZeneca's COVID-19 antibody treatment shows promising results in clinical trialsAstraZeneca has announced that its COVID-19 antibody treatment has shown promising results in clinical trials. The treatment, which is designed to prevent severe disease and hospitalization, could provide an important new tool in the fight against the virus.##Title: Novartis receives FDA approval for new treatment for advanced breast cancerNovartis has received FDA approval for a new treatment for advanced breast cancer. The drug, which targets a specific genetic mutation, has been shown to significantly improve progression-free survival in patients with the disease.##Title: Roche announces positive results from phase 3 trial of Alzheimer's drugRoche has announced positive results from a phase 3 trial of its Alzheimer's drug. The drug, which is designed to target the underlying cause of the disease, showed significant improvement in cognitive function and daily living activities in patients with early-stage Alzheimer's.##Title: Johnson & Johnson to invest $6.5 billion in expanding vaccine production capacityJohnson & Johnson has announced plans to invest $6.5 billion in expanding its vaccine production capacity. The company aims to increase production of its COVID-19 vaccine as well as other vaccines in its portfolio, helping to address global supply shortages.##Title: Merck receives FDA approval for new treatment for certain types of lung cancerMerck has received FDA approval for a new treatment for certain types of lung cancer. The drug, which targets a specific genetic mutation, has been shown to improve overall survival in patients with advanced disease.##Title: Gilead Sciences announces collaboration with Novartis on HIV researchGilead Sciences has announced a collaboration with Novartis on HIV research. The companies will work together to develop new treatments for HIV, with a focus on addressing drug resistance and improving outcomes for patients with the virus.## Title: Eli Lilly receives FDA approval for new treatment for migraineEli Lilly has received FDA approval for a new treatment for migraine. The drug, which is administered through an injection, has been shown to provide rapid relief from migraine symptoms and reduce the frequency of attacks in patients with the condition.

In today's episode, I was very excited to sit down with Dr. Ilana Gurevich to discuss the latest, most effective approaches to GI conditions. We explore the usage of sulfur for the gut, the role of the mitochondria in the body's overall health, treating parasites, as well as SIBO and Candida. We'll also share recommended protocols for each condition. Listen now!   

In this episode of It Happened To Me, we dive into the world of Niemann-Pick Type C (NPC), a rare genetic condition that affects fewer than 1,000 people in the United States. NPC is a progressive disorder impacting the brain, nerves, and major organs, often referred to as "childhood Alzheimer's" due to its neurological effects. Our guests bring both personal and professional expertise to the conversation: Barbara Lazarus is the mother of two adult sons (now in their 30s), who have Niemann-Pick Type C disease.  David is taking Myplyffa, through an expanded access program.  Both David and her brother Daniel have been seen at UCSF Benioff Oakland Children's Hospital in the Bay Area of California.  She is a knowledgeable patient advocate of NPC.  Dr. Caroline Hastings is a Pediatric Hematologist Oncologist and Professor of Pediatrics at UCSF Benioff Children's Hospital Oakland. In addition to her specialization in pediatric cancer and blood diseases, including a focus on tumors of the brain and spinal cord, her clinical and academic interests have focused on children and adults with rare lysosomal storage diseases. Her particular area of expertise and interest is in Niemann-Pick Type C disease, a rare debilitating genetic disease that until now has been elusive to a therapeutic intervention. She has been involved in developing new drugs and treatment strategies with the hope to improve quality of life and longevity for these patients.C. Together, they provide a comprehensive look at NPC, from its symptoms and genetic causes to the challenges of diagnosis and the hope brought by new FDA-approved treatments like Miplyffa. Topics Discussed: How Niemann-Pick Type C affects the body. Early signs, symptoms, and progression of NPC in children and adults. The genetics of NPC and its inheritance patterns. The challenges of diagnosing such a rare condition and the role of genetic counseling. Insights into the newly FDA-approved treatment, Miplyffa, and its impact on patients like Barbara's son David. The importance of specialized medical centers for NPC care and the role of advocacy and community support. Key Takeaways: NPC is caused by mutations in the NPC1 and NPC2 genes, leading to the buildup of cholesterol and lipids in cells. Early diagnosis and specialized care are crucial for managing the condition and accessing treatments. The approval of Miplyffa marks a significant milestone, offering new hope for families affected by NPC. Resources Mentioned: UCSF Benioff Oakland Children's Hospital Neurology Center National Niemann Pick Disease Foundation Information on FDA-approved treatments like Miplyffa Connect with Us: Stay tuned for the next new episode of “It Happened To Me”! In the meantime, you can listen to our previous episodes on Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “It Happened To Me”.    “It Happened To Me” is created and hosted by Cathy Gildenhorn and Beth Glassman. DNA Today's Kira Dineen is our executive producer and marketing lead. Amanda Andreoli is our associate producer. Ashlyn Enokian is our graphic designer.   See what else we are up to on Twitter, Instagram, Facebook, YouTube and our website, ItHappenedToMePod.com. Questions/inquiries can be sent to ItHappenedToMePod@gmail.com.   

Welcome to the Evidence-Based Hair Podcast, hosted by dermatologist and hair loss specialist Dr. Jeff Donovan. In this episode, Dr. Donovan explores a groundbreaking study published in the journal Curious, highlighting the effectiveness of the JAK1 inhibitor, upadacitinib, in treating recalcitrant dissecting cellulitis of the scalp. Dissecting cellulitis, a challenging form of scarring alopecia, often affects males and presents with debilitating symptoms. While traditional treatments like isotretinoin and antibiotics offer relief for some, they aren't always effective. The study discusses a case where upadacitinib brought significant improvement after conventional options were exhausted. Dr. Donovan provides a comprehensive overview of the study, emphasizing the potential of JAK inhibitors as third-line treatments in managing persistent dissecting cellulitis. He also shares insights on the broader implications for future research and treatment strategies. Join Dr. Donovan next week for an analysis of a study on alopecia areata and cardiovascular comorbidities, and don't miss the annual "Top 20 of 2024" event on December 30th. For more information about the Donovan Hair Academy's programs, visit their website.     STUDY REFERENCED IN THIS EPISODE Zahidul Islam, Michelle Toker, Isha M Gandhi, Ariel Sher, Kristina Campto. Improvement of Recalcitrant Dissecting Cellulitis of the Scalp After a Trial of Upadacitinib. Cureus . 2024 Jan 16;16(1):e52377. doi: 10.7759/cureus.52377. eCollection 2024 Jan.  

Guest: Michele Lambert, MD, MSTR New treatments are on the horizon for patients with immune thrombocytopenia (ITP). Dr. Michele Lambert shares insights on how BTK inhibitors and immune-targeting drugs aim to address the root causes of ITP and offer more personalized care for patients. Dr. Lambert, the Medical Director of the Special Coagulation Laboratory and a physician in the Division of Hematology at Children's Hospital of Philadelphia, presented on this topic at the 2024 American Society of Hematology Annual Meeting.

Guest: Michele Lambert, MD, MSTR New treatments are on the horizon for patients with immune thrombocytopenia (ITP). Dr. Michele Lambert shares insights on how BTK inhibitors and immune-targeting drugs aim to address the root causes of ITP and offer more personalized care for patients. Dr. Lambert, the Medical Director of the Special Coagulation Laboratory and a physician in the Division of Hematology at Children's Hospital of Philadelphia, presented on this topic at the 2024 American Society of Hematology Annual Meeting.

It's World Antimicrobial Resistance Awareness Week (WAAW) and the theme is "Educate. Advocate. Act now". It's a yearly global campaign, raising awareness of antimicrobial resistance (AMR) and promoting ways to reduce the spread of drug-resistant infections. To mark the occasion, MTPConnect's Andrew Bowskill, Co-chair of the Australian Antimicrobial Resistance Network, AAMRNet, and Anne Harris, Managing Director of Pfizer Australia and New Zealand join host Caroline Duell to discuss new approaches to fighting superbugs. Why it needs to be tackled holistically with a ‘One Health' approach across all sectors, including the environment, animal health and agriculture. They discuss the role of vaccines as the first line of defence, and why a new subscription-style reimbursement model in Australia will help support equitable access to new treatments and restimulate investment in antibiotics R&D to meet future needs. We also find out how the recent upgrade to Pfizer's manufacturing facility in Melbourne is an important development in the fight against AMR.

Current strategies to manage Erectile dysfunction (ED) and what can be improved History of ED, including duration; understanding if it's organic or psychogenic key to treating it Relationship of ED with underlying vascular comorbidities What investigations can help diagnosis for targeted treatment Overview of treatments available, including upcoming new ones   Host: Dr David Lim | Total Time: 32 mins Facilitator: Dr David Lim, General Practitioner Expert: Dr Michael Gillman, General Practitioner Register for our fortnightly FREE WEBCASTSEvery second Tuesday | 7:00pm-9:00pm AEDT Click here to register for the next oneSee omnystudio.com/listener for privacy information.

In today's episode, Dr. Addison Killeen answers a listener's question about expanding their practice beyond routine hygiene appointments. After acquiring their office in 2021, they've seen consistent growth, but now face the challenge of maintaining a healthy patient base. Dr. Killeen shares strategies like building stronger relationships with patients to introduce aesthetic treatments, clear aligners, and reengaging those on the "watch" list. Tune in for practical advice on how to elevate your surface offerings and grow your practice. For more information about Dr. Addison Killeen, visit: www.addisonkilleen.com or interact with him on a daily basis at www.DentalSuccessNetwork.com

Dr. Philip Gold is one of the world's leading researchers of depressive illness. He is here today to discuss the correlation and body's response to depression and stress, the role of inflammation in depression and how anti-inflammatory agents can help. Research notes Depression represents a dysregulation of the brain's stress response system that we depend upon for survival - why it is so critical to address stress and tips for doing it. Dr. Gold discusses data revealing depression is a total body disease that shortens life by 7 - 10 years, and that it brings increased risk of premature onset of coronary artery disease, stroke, diabetes and osteoporosis. He also discusses a new science of gene therapy including a treatment overcoming the gene mutation that interferes with resiliency, promotes vulnerability to depression, and inhibits the capacity of antidepressants to work effectively Get his new book here: https://www.amazon.com/Breaking-Through-Depression-Generation-Revolutionary/dp/1538724618/ref=tmm_hrd_swatch_0?_encoding=UTF8&qid=&sr=

Dr. Linda McAllister-Lucas is an NIH-funded physician-scientist who investigates how dysregulated intracellular signaling contributes to inflammatory disease and cancer. She co-directs a research laboratory with her husband Dr. Peter Lucas, a member of the faculty in the Department of Pathology. Their joint Lucas / McAllister Laboratory comprises ten scientists at varying stages of training. Learn more about Dr. McAllister's research.

First up this week, Staff Writer Adrian Cho talks with host Sarah Crespi about a fusion company that isn't aiming for net energy. Instead, it's looking to sell off the high-energy neutrons from its fusion reactors for different purposes, such as imaging machine parts and generating medical isotopes. In the long run, the company hopes to use money from these neutron-based enterprises for bigger, more energetic reactors that may someday make fusion energy. Next, we hear from Tian Du, a Ph.D. candidate in the Dr John and Anne Chong Lab for Functional Genomics at the University of Sydney. She talks about finding antivenom treatments by screening all the genes in the human genome. Her Science Translational Medicine paper focuses on a strong candidate for treating spitting cobra bites, but the technique may prove useful for many other venomous animal bites and stings, from jellyfish to spiders. This week's episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi, Adrian Cho Learn more about your ad choices. Visit megaphone.fm/adchoices

First up this week, Staff Writer Adrian Cho talks with host Sarah Crespi about a fusion company that isn't aiming for net energy. Instead, it's looking to sell off the high-energy neutrons from its fusion reactors for different purposes, such as imaging machine parts and generating medical isotopes. In the long run, the company hopes to use money from these neutron-based enterprises for bigger, more energetic reactors that may someday make fusion energy. Next, we hear from Tian Du, a Ph.D. candidate in the Dr John and Anne Chong Lab for Functional Genomics at the University of Sydney. She talks about finding antivenom treatments by screening all the genes in the human genome. Her Science Translational Medicine paper focuses on a strong candidate for treating spitting cobra bites, but the technique may prove useful for many other venomous animal bites and stings, from jellyfish to spiders. This week's episode was produced with help from Podigy. About the Science Podcast Authors: Sarah Crespi, Adrian Cho Learn more about your ad choices. Visit megaphone.fm/adchoices

Join Dr. Szot, Dr. Larson, Dr. Shim, and Dr. Reist as they discuss new therapeutic agents for the treatment of Alzheimer's disease and their role in management of the disease. CME Credit Available:  https://uiowa.cloud-cme.com/course/courseoverview?P=0&EID=66930  Resources:  Lecanemab in Early Alzheimer's Disease. New England Journal of Medicine. DOI: 10.1056/NEJMoa2212948. PMID: 36449413 Lecanemab: Looking Before We Leap. Neurology. DOI: 10.1212/WNL.0000000000207505. PMID: 37479527 Host: Joseph Szot, MD Associate Dean for Continuing and Integrated Medical Education Clinical Professor of Internal Medicine University of Iowa Carver College of Medicine Guests: Scott Larson, MD Clinical Assistant Professor of Family Medicine University of Iowa Department of Family Medicine Jeff Reist, PharmD Clinical Associate Professor of Pharmacy Practice and Science Director, Pharmacy Practice Learning Center University of Iowa College of Pharmacy HyungSub Shim, MD of Neurology and Psychiatry Clinical Assistant Professor Medical Director of the Memory Disorders Clinic University of Iowa Department of Neurology and Psychiatry Financial Disclosures:  Dr. Joseph Szot, his guests and the members of the planning committee for Rounding@IOWA have no relevant financial relationships to disclose. CME Credit Designation: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this enduring material for a maximum of 0.5 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurses: The University of Iowa Roy J. and Lucille A. Carver College of Medicine designates this activity for a maximum of 0.5 ANCC contact hour. Other Health Care Providers: A certificate of completion will be available after successful completion of the course. (It is the responsibility of licensees to determine if this continuing education activity meets the requirements of their professional licensure board.)  

As part of the 2024 Prostate Cancer Patient Conference, Dr. Rahul Aggarwal reviews emerging treatment approaches for advanced prostate cancer, including developments for antibody-drug conjugates, immunotherapy (T cell engagers), targeted radiation, and targeting Androgen Receptor Signaling. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39772]

As part of the 2024 Prostate Cancer Patient Conference, Dr. Rahul Aggarwal reviews emerging treatment approaches for advanced prostate cancer, including developments for antibody-drug conjugates, immunotherapy (T cell engagers), targeted radiation, and targeting Androgen Receptor Signaling. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39772]

As part of the 2024 Prostate Cancer Patient Conference, Dr. Rahul Aggarwal reviews emerging treatment approaches for advanced prostate cancer, including developments for antibody-drug conjugates, immunotherapy (T cell engagers), targeted radiation, and targeting Androgen Receptor Signaling. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39772]

As part of the 2024 Prostate Cancer Patient Conference, Dr. Rahul Aggarwal reviews emerging treatment approaches for advanced prostate cancer, including developments for antibody-drug conjugates, immunotherapy (T cell engagers), targeted radiation, and targeting Androgen Receptor Signaling. Series: "Prostate Cancer Patient Conference" [Health and Medicine] [Show ID: 39772]

More clinical pearls from ACP #IM2024, including emerging infectious diseases in the US (malaria, dengue, super gonorrhea, and a resurgence of syphilis), new C. diff treatments, coagulopathy and cirrhosis, fatty liver disease, HFpEF, peripheral arterial disease, Lp(a) and ApoB, CAR T-cells for autoimmune disease, SGLT2i for gout, and hematology updates. Paul and Watto are joined by Drs. Nora Taranto, Beth Garbitelli, and of course Chris “The Chiu Man” Chiu. Claim CME for this episode at curbsiders.vcuhealth.org! Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME Show Segments 00:00 Tropical Diseases: Resurgence of Malaria and Dengue Fever 03:44 Infectious Diseases: Syphilis Rates and New Treatments for C. diff 08:28 Coagulopathy and Cirrhosis: Managing Hemostasis and Portal Vein Thrombosis 11:34 Fatty Liver Disease: Risk Stratification and Treatment 14:59 Cardiology Updates: Cardiovascular Kidney Metabolic Syndrome 31:03 New Medications for Hypertension 32:54 Renal Denervation and Hypertension 33:51 Lp(a) Drugs and Their Potential 36:01 Peripheral Arterial Disease and Claudication 38:10 SGLT2 Inhibitors and Gout 41:50 APO-B and LDL Cholesterol 42:45 Secondary Hypogonadism and Head and Neck Radiation 45:30 VEXAS: A Genetic Autoimmune Condition 49:08 Obesity-Induced Leukocytosis 52:49 CAR T-Cell Therapy in Rheumatologic Diseases Credits Producers/Writers/Show Notes: Matthew Watto MD, FACP; Paul Williams MD, FACP, Nora Taranto MD, Chris Chiu MD, Beth Garbitelli MD CME, Cover Art: Beth Garbitelli MD Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP    Reviewer: Nora Taranto MD Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP Technical Production: PodPaste Sponsor: Litter Robot Go to stopscooping.com/CURB and enter promocode CURB to save an EXTRA $50 on any Litter-Robot bundle. Sponsor: Freed You can try Freed for free right now by going to freed.ai. And listeners of Curbsiders can use code CURB50 for $50 off their first month. Sponsor: Beginly Visit beginlyhealth.com/curbsiders for the job matching platform for every Physician and Advanced Practice Clinician, from training to practice

Food allergies are a major problem – common, potentially deadly, and without effective medicines to prevent them from occurring. But earlier this year, researchers and doctors published a clinical trial reporting an effective new treatment for preventing allergic food reactions. In today's episode of Beyond the Abstract, Derek and Dan dive into the science behind the new treatment and what it might mean for the future of combating a deadly disease. Article discussedWood et al., Omalizumab for the Treatment of Multiple Food Allergies. New England Journal of Medicine. 2024 (https://www.nejm.org/doi/full/10.1056/NEJMoa2312382)The information presented here is not medical advice. Consult your physician for any questions regarding your personal health.

Why talk to a hematologist about mast cell disease and systemic mastocytosis treatment? Dr. Douglas Tremblay, a leading hematologist, joins Dr. G and Kortney to discuss the role of a hematologist-oncologist in diagnosing and treating mastocytosis. We discuss bone marrow's vital role in diagnosing and treating systemic mastocytosis.  Dr. Tremblay discusses the latest KIT inhibitors, a promising group of medications, and explains the difference between indolent and advanced systemic mastocytosis. He clarifies how KIT inhibitors work and emphasizes the importance of managing side effects. Finally, Dr. Tremblay provides insights into the future of KIT inhibitor approval and explores the possibility of participating in a clinical trial for Bezulastinib.  What we cover in this episode about treating systemic mastocytosis: What is a hematologist looking at with mast cell disease patients? Mast cell diseases and the role of bone marrow Bone marrow biopsy for systemic mastocytosis  What is a bone marrow biopsy? Information bone marrow biopsy provides for diagnosis KIT mutation  KIT mutation testing in bone marrow and blood (digital droplet PCR) Indolent Mastocytosis versus Advanced Mastocytosis Current research for treating mast cell disease How KIT inhibitors work Do KIT inhibitors weaken the immune system? KIT Inhibitors discussed in this episode: Avapritinib Bezulastinib Elenestinib Are KIT inhibitors a cure for mast cell disease? Determining the tolerance for side effects of medications when researching and adding new medicines for diseases  The meaning of ‘NIB' in the medication names The timeline for the new KIT inhibitors approval The type of patient that can participate in the clinical trials for Bezulastinib Resources about mast cell disease: Dr. Tremblay: https://profiles.mountsinai.org/douglas-a-tremblay Dr. Tremblay's email: douglas.tremblay@mssm.edu  Mast Cell Disease Overview: https://allergyasthmanetwork.org/health-a-z/mast-cell-diseases/ What is Anaphylaxis? https://allergyasthmanetwork.org/anaphylaxis/ What is Epinephrine? https://allergyasthmanetwork.org/anaphylaxis/what-is-epinephrine/ The Mast Cell Disease Society: https://tmsforacure.org/ Current studies enrolling patients: https://tmsforacure.org/clinical-trials/

Dr. Lauren Zimski brings expert dry eye care to the Denver area. She and Dr. Amigues treat many of the same patients! Tune in to learn all about dry eye syndrome. The discussion dives into the innovative treatments provided by Dr. Zimksi, which go beyond the limited options provided by most ophthalmologists: artificial tears and punctal plugs. You'll also learn about the causes of dry eye when it comes to rheumatologic conditions. This is the first episode in a two part series.  Next week, we'll discuss in more detail the correlations between rheumatologic conditions and dry eye. As a board-certified ophthalmologist with a special interest in ocular surface disease, Dr. Zimski spent many years in private practice where she saw an increasing number of patients struggling with eye discomfort, redness and fluctuating vision. Finding that common recommendations such as artificial tears were rarely effective, Dr. Zimski decided to seek out better solutions through research studies, conferences, and engaging thought leaders in the ocular surface disease space. With various treatment options available in the market, she wanted to bring the best new technology into her practice and to integrate it in a stepwise approach to achieve the best results for her patients. You can find lauren at https://www.laurenzimskimd.com, and be sure to give her a follow on social media for dry eye tips and insights:Instagram: @lauren_zimskimdFacebook: dryeyedenverEpisode Content ____________________________________________________--- 00:01 - Introduction--- 00:26 - Introducing Dr. Lauren Zimski--- 01:11 - Dr. Zimski's Journey into Ophthalmology and Dry Eyes--- 02:17 - Concerns about Younger Patients with Severe Dry Eye--- 03:40 - Definition of Dry Eyes in Ophthalmology--- 04:50 - Approach to Diagnosing Dry Eyes--- 06:40 - Connection Between Dry Eyes and Skin Conditions--- 08:44 - Treatment of Dry Eyes: Dermatologist's Involvement--- 09:12 - Traditional Treatments: Artificial Tears and Lacrimal Plugs--- 10:00 - New Tools and Imaging Systems in Diagnosis--- 11:00 - Importance of Evaluating Eyelid Conditions and a Thorough Diagnostics Process--- 15:12 - Stepwise Treatment Process for Dry Eyes--- 15:40 - Inflammadry Test--- 16:37 - Explanation of Puctal Plugs--- 18:00 - IPL (Intense Pulse Light Therapy) for Dry Eyes--- 21:25 - Fish Oil and Other Home Care Regimens--- 26:06 - Hope for Patients and New Treatments in Dry Eye Care--- 28:38 - How to Contact Dr. Lauren Zimski____________________________________________________________________Learn more about Rheumatology on Dr. Amigues' education focused channel, @Rheumatology101  And give us a follow on social media! We greatly appreciate your support. https://www.instagram.com/unabridgedmd/https://www.facebook.com/UnabridgedMDhttps://www.tiktok.com/@unabridgedmdAre you, or someone you love, looking for a rheumatologist near you? Maybe you queried Google for the “best rheumatologist in Denver” and felt that no other arthritis clinic in Denver really seemed personable? Or maybe you are simply looking for a doctor who will listen to you and work with you to achieve disease remission? Well, you have come to the right place. UnabridgedMD has the best rheumatologist in Denver, Colorado and we cannot wait to work with you.Click here to get in touch: https://www.unabridgedmd.com Or give us a call: 303-731-4006#rheumatologist #unabridgedmd #dryeyesyndrome #denver #drIf you live in Colorado and are looking for a rheumatologist to help you achieve disease remission, email or contact us at UnabridgedMD.com. We are the first direct care rheumatology in Colorado and can see you within a week!

Today's podcast guest is the remarkable Doctor Cudkowicz, a neurologist and neuroscientist renowned for her work on amyotrophic lateral sclerosis (ALS). A Julieanne Dorn Professor of Neurology at Harvard Medical School and director of the Sean Healey ALS clinic at Massachusetts General Hospital, Merit has been pivotal in leading collaborative research and clinical trials for ALS. With an impressive academic journey from MIT to Harvard, her passion for neuroscience and patient care is evident. Merit's work brings hope to countless individuals affected by this condition. Get ready to be inspired by her groundbreaking contributions and insights into the world of neurology and neuroscience!   Tim Green's "Nothing Left Unsaid" is a weekly podcast hosted by Tim and Troy Green. Tim is a former first round NFL draft pick, member of the College Football Hall of Fame, New York Times #1 Bestselling Author, former Fox broadcaster, NPR contributor, family man, ALS advocate, and so much more. Each week, Tim and Troy will sit down with interesting people to have thoughtful conversations. The guests will range from celebrities, athletes, academics, doctors, authors, and more. As Tim battles his ALS diagnosis, nothing is out of bounds and there will be nothing left unsaid. #NothingLeftUnsaid #TimGreen #podcast   SPONSORS  ElevenLabs: Thanks to ElevenLabs (https://elevenlabs.io/) for supporting this episode and powering Tim's voice.  Barclay Damon: Thank you to my law firm, for supporting this episode (https://www.barclaydamon.com/).    SOCIAL Twitter: https://twitter.com/nlutimgreen  Facebook: https://www.facebook.com/TGNothingLeftUnsaid  Instagram: https://www.instagram.com/tgnlu/  TikTok: https://www.tiktok.com/@tgnothingleftunsaid    AUDIO ONLY  Spotify: https://open.spotify.com/show/5fhcANt7CSnYvgBlgxpVVa  Apple Podcasts:https://podcasts.apple.com/us/podcast/nothing-left-unsaid/id1734094890    PERSONAL  Tackle ALS: https://www.tackleals.com/ Tim Green Books: https://authortimgreen.com/

200 million women worldwide battle endometriosis, a condition with no cure and limited treatment options for decades – until now. Discover the latest breakthroughs in treatment and womb transplant successes in today's episode.  Subscribe to podcast updates: https://form.jotform.com/223614751580152 Ask Ric: https://www.thetayf.com/pages/ask-ric ----- Follow Ric on social media: Facebook: https://www.facebook.com/RicEdelman Instagram: https://www.instagram.com/ric_edelman/ LinkedIn: https://www.linkedin.com/in/ricedelman/ X: https://twitter.com/ricedelman YouTube: https://www.youtube.com/@RicEdelman ----- Brought to you by: Invesco QQQ: https://www.invesco.com/qqq-etf/en/home.html Schwab: https://www.schwab.com/ Bitwise: https://www.bitwise.com Disclosure page: https://www.thetayf.com/pages/sponsorship-disclosure-fee -----

As researchers push to find a cure for Alzheimer's disease, there are lots of new and exciting discoveries and drug approvals being made. We enlisted Dr. Parichita Choudhury, a cognitive neurologist at Banner Sun Health Research Institute, to answer some of our most-requested questions about what all of this means. She untangles the latest drug trial results, what the names of these drugs mean, and how healthcare systems implement the use of these breakthrough treatments. 

In this episode, I have the pleasure of sitting down with Dr. Troy Spurrill to delve into the complexities of Lyme disease and mold toxicity. We explore their causes, symptoms, and treatments, and I emphasize the holistic nature of health, which includes emotional, physical, mental, and spiritual aspects. Dr. Spurrill shares an inspiring story of one of his patients, highlighting the incredible power of mindset in the healing process. We also touch on the spiritual aspects of health, discussing the importance of forgiveness and vulnerability. Throughout our conversation, we underscore the interconnectedness of emotional well-being and physical health.Chapters(00:00) Podcast Introduction(02:22) Guest Introduction(04:39) Discussion on Lyme Disease(07:51) Increase in Lyme Disease Cases(10:33) Symptoms of Lyme Disease(13:26) Impact of Lifestyle and Emotional Well-being(16:58) Forgiveness and Healing(19:09) The Mind of Christ(20:22) Receiving God's Love and Healing(24:13) New Treatments for Lyme disease(27:04) Mold Toxicity and its Effects(30:51) Addressing Emotional Health in Healthcare(34:42) Emotional and Physical Healing(35:36) Closing Remarks and PrayerResources mentioned:Synapse Website Green DrinkConnect with today's guest:InstagramFacebookDr. Troy Spurrill is the CEO and founder of Synapse: A Center For Health and Healing. He received a Bachelor of Science in Molecular Biology from the University of Manitoba and a Doctor of Chiropractic from Northwestern Health Sciences University, and has extensive training in Functional Neurology, Functional medicine, Nutrition, and Applied Kinesiology.Dr. Spurrill travels extensively conducting seminars on the subjects of disease prevention and healing through a faith-filled healthy lifestyle. He has authored the book Formula For Life and is credited with the development of a brain-body technique to reverse the cycles of post-traumatic stress disorder and cumulative stress syndromes. Dr. Spurrill's next book will be coming out later this year.His mission is to impact the well-being of people around the world by providing solutions to complicated life issues, and to create sanctuaries that promote the restoration and perpetuation of health, happiness, and prosperity! Dr. Spurrill's company can be found in Eagan, Minnesota.P.S. If you're just checking out the show to see if it's a good fit for you, welcome!If you're really serious about becoming Visibly Fit, you'll get the best experience if you download the worksheets available at https://wendiepett.com/visiblyfitpodcast.

Akrivia Health provides research data, clinical trial optimization, and molecular characterization for mental health and dementia. We speak with David Newton, COO & Co-Founder of Akrivia Health, about how they use AI to process free text notes into structured data, all while safeguarding patient privacy.

Last week, the Food and Drug Administration approved two new gene therapies to treat sickle cell disease. Roughly 100,000 people in the U.S. live with the debilitating and painful blood disorder, most of whom are African American. One of these “milestone treatments'' is a drug using powerful gene-editing technology never before approved for human use. It can repair a mutation that produces sickle-shaped red blood cells that can lead to stroke, organ damage and premature death.  But the millions of dollars the treatments cost is just one of the barriers facing patients like Jayla Eddins, a high school senior in Salem, and her mother, Jamie Eddins, who helps manage her daughter’s illness. Dr. Trisha Wong is an associate professor of pediatrics in the division of hematology and oncology at Oregon Health & Science University. They join us to talk about the physical and emotional toll of the disease as new breakthroughs emerge to treat it. 

Ep. 73 - New treatments for arthritic pets - Show NotesOur pets can suffer from arthritis, just like their human owners. For years, the only treatment has been non-steroidal anti-inflammatory drugs (NSAIDS.) However, two drugs have recently been approved by the FDA for our pets.Dr. Tamara Grubb returns to the podcast to explain how these new drugs, utilizing the science of monoclonal antibodies, are revolutionizing the treatment of osteoarthritis for our pets.Here are links to information we talked about today:Listen to Dr. Tamara Grubb's first visit to The Family Pet Podcast in Episode 35This explainer from the Cleveland Clinic explains monoclonal antibodies in human medicine and is a good insight into what the future might hold for pet medicineDog owners can learn about LibrelaCat owners can learn about SolensiaZoetis announced the U.S. commercial launch of Librela (bedinvetmab injection), which the company says is the first and only anti-NGF monoclonal antibody treatment to control canine osteoarthritis pain. The product in May received approval from the FDA. Got a question for Michael and Stephen? Run across something interesting you want to share with the show? Do you have a topic idea for a future episode? Send it to us at thefamilypetpodcast@gmail.com. 

The National Security Hour with LTC Sargis Sangari USA (Ret.) – Dr. Robert Beckman, C-Founder, Executive Director of TreatNOW.org, and Chief Knowledge Officer at the Foundation for the Study of Inflammatory Disease (foundsid.org), joins me to discuss the lingering effects of Traumatic Brain Injury (TBI) & Post-traumatic stress disorder (PTSD) and the means and the multiple ways of new treatments to address them.

On this summer episode, we discuss some of the latest news topic on the docket! Information about new treatments for Erectile dysfunction recently announced that has many people intrigued. New data on Testosterone replacement in men. Maybe its safer than initially thought? New data on hysterectomies performed on women younger than 50 may lead to concerning side effects. We discuss these topics and many more on this weeks episode of the Health and Wellness Connection. Donate to the show via cash app via $drbarryhealth.

IN THIS EPISODE OF THE HUMAN UPGRADE™… Vincent Pedre, M.D., explains how consuming too much sugar can lead to insulin resistance and diabetes by causing shifts in the microbiome that reduce insulin signaling. He also highlights how omega-6 fats found in processed foods contribute to inflammation and chronic disease by carrying lipopolysaccharide toxins through cell membranes. For over a decade, board-certified internist and Functional Medicine certified practitioner, Dr. Pedre, founder of Happy Gut Life, has helped people improve their well-being and quality of life by building the foundation of gut health that supports total physical and mental wellness. He believes that healing begins in the kitchen through the foods we eat. He brings together years of research and clinical experience to offer you real solutions in his newest book, “The GutSMART Protocol: Revitalize Your Health, Boost Your Energy, and Lose Weight in Just 14 Days with Your Personalized Gut-Healing Plan.”The balance between good and bad bacteria is both important and nuanced—more microbial diversity in the gut is not always better. "The focus should be on metabolomics, not just diversity when it comes to gut bacteria,” Dr. Pedre says. Another focus includes gut interrelationships and the seven big systems in your body affected by leaky gut: skin, airway, brain, joints, energy, metabolism, and immune system.Watch this episode on YouTube!Find all the links and resources in the show notes.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Anti-aging Powerhouse: https://spermidinelife.us/dave , use code DAVE25 to save 25% on your first purchaseMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountDave Asprey's NEW Book! “Smarter Not Harder: The Biohacker's Guide to Getting the Body and Mind You Want” is out now. https://daveasprey.com/books/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.