Podcasts about Glioblastoma

My guest is Dr. David Fajgenbaum, MD, professor of translational medicine and human genetics at the University of Pennsylvania. He explains how, unbeknownst to most doctors, many approved medications can successfully treat or even cure diseases other than the ones they are typically used to treat. He shares his story of escaping death from Castleman's disease by discovering a life-saving treatment using repurposed drugs that were approved for other purposes. Our conversation explores how researchers, physicians, and you—the general public—can explore novel treatments and cures to conditions the medical profession has deemed untreatable, including cancers. We also discuss the crucial role of mindset in battling diseases and the lesser-known use of compounds to promote health and longevity. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AGZ by AG1: https://drinkagz.com/huberman Eight Sleep: https://eightsleep.com/huberman Rorra: https://rorra.com/huberman David: https://davidprotein.com/huberman Function: https://functionhealth.com/huberman Timestamps (0:00) David Fajgenbaum (4:06) Self-Agency in Healthcare; New Uses for Old Medicines (6:44) Other Uses of Aspirin & Viagra; Drug Development & Approved Use (8:53) Lidocaine & Breast Cancer; Pharmaceutical Companies & Incentives (11:36) Sponsors: Eight Sleep & Rorra (14:16) Pharmaceutical Companies, Patents & New Uses; Lithium (18:40) Tools: Finding Reliable Health Sources, Asking Questions & Disease Organizations; DADA2 Treatment (21:53) Medical Community & Connections; Integrated Medical Databases (24:36) Drug Repurposing, Thalidomide, Pembrolizumab (28:45) Medical Research Databases, Mapping Disease Connections (33:51) Every Cure Database & Programs, Bachmann-Bupp Syndrome; Colchicine & Heart Disease (37:57) Sponsors: AGZ by AG1 & David (40:41) David's Medical & Career Journey, Glioblastoma, Castleman Disease (49:10) Autoimmune Disease, Driven Personality, Stress & Immune System (52:52) Castleman Disease, Treatment, Chemotherapy (55:54) Physician Continuing Education, Santa Claus Theory of Civilization; Science Collaboration (1:03:32) Medical School, Relapse & “Overtime”, Finding a New Treatment, Rapamycin (1:12:46) Sport, Football & Resilience; Challenge & Personal Growth, Family (1:18:41) Sponsor: Function (1:20:29) Social Support; “Overtime”, Gratitude (1:23:19) Business School, Castleman Disease Treatment; Repurposing Drugs & AI (1:28:29) Drug Repurposing, POEMS Syndrome; Mitigating Risk (1:35:32) Nicotine, Compounds for Preventive Health; GLP-1 Agonists (1:40:51) Bioprospecting, Drug Development; AI, Prioritization & Novel Connections (1:46:18) Healthcare & Children; Hope, Action & Impact Circuit; Challenge & Super-Agers (1:52:50) Get Involved with Every Cure (1:56:20) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Curing with Sound, we explore a groundbreaking approach to one of medicine's toughest cancers, glioblastoma (GBM), with Michael Canney, PhD, Chief Scientific Officer at Carthera. GBM is the most aggressive form of brain cancer, notoriously hard to treat because the blood-brain barrier (BBB) blocks many life-saving drugs from reaching tumor cells. With survival rates of just one to two years, new approaches are urgently needed. Dr. Canney shares how Carthera's SonoCloud-9, an implantable, therapeutic ultrasound device, temporarily opens the BBB and enhances the delivery of circulating drugs to the brain. He also discusses the SONOBIRD clinical trial, comparing the use of Carthera's SonoCloud-9 device combined with chemotherapy to standard-of-care therapies in patients with recurrent GBM. Discussion highlights: Phase III SONOBIRD Trial: The largest clinical trial in Carthera's history, enrolling 560 patients across the United States and Europe. The trial's goal is to demonstrate a survival advantage for patients with recurrent GBM when BBB opening is combined with the delivery of carboplatin chemotherapy, as compared with standard of care. Revolutionizing Drug Delivery: How SonoCloud-9 opens the BBB to increase carboplatin concentrations five- to seven-fold, potentially unlocking the full potential of existing cancer drugs that previously couldn't reach brain tumors. EPISODE TRANSCRIPT ---------------------------- QUESTIONS? Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances.  Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation.  FUSF SOCIAL MEDIA LinkedIn X Facebook Instagram TikTok YouTube FUSF WEBSITE https://www.fusfoundation.org SIGN UP FOR OUR FREE NEWSLETTER https://www.fusfoundation.org/newsletter-signup/ READ THE LATEST NEWSLETTER https://www.fusfoundation.org/the-foundation/news-media/newsletter/ DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK) https://www.fusfoundation.org/read-the-tumor-by-john-grisham/

Evening Prayer (people with Glio Blastoma, people recovering from accidents) #prayer #pray #eveningprayer #jesus #god #holyspirit #aimingforjesus #healing #bible #love #peace #glioblastoma #accident #recovering #recoveringfromtrauma Thank you for listening, our heart's prayer is for you and I to walk daily with Jesus, our joy and peace aimingforjesus.com YouTube Channel https://www.youtube.com/@aimingforjesus5346 Instagram https://www.instagram.com/aiming_for_jesus/ Threads https://www.threads.com/@aiming_for_jesus X https://x.com/AimingForJesus Tik Tok https://www.tiktok.com/@aiming.for.jesus

BUFFALO, NY – October 14, 2025 – A new #research paper was #published in Volume 16 of Oncotarget on October 13, 2025, titled “Treatment of glioblastoma with tumor-specific amplitude-modulated radiofrequency electromagnetic fields.” The study, led by Hugo Jimenez from Wayne State University School of Medicine, Karmanos Cancer Institute, introduces a novel treatment approach for glioblastoma, an aggressive and often treatment-resistant brain cancer. The findings open a new potential path for patients who currently have limited therapeutic options. The approach uses a device developed by TheraBionic that delivers extremely low levels of radiofrequency electromagnetic fields, tuned to frequencies associated with glioblastoma. In laboratory experiments, this therapy significantly slowed the growth of multiple glioblastoma cell lines. It was especially effective against tumor stem cells, which are known to resist standard treatments and drive cancer reappearance. Researchers also found that the treatment's effects depend on a calcium channel in tumor cells known as Cav3.2 (CACNA1H). When this channel was blocked, the therapy lost its effectiveness, highlighting the channel's essential role in how tumor cells respond to the signal. The therapy also disrupted the process of cell division by interfering with the mitotic spindle, a structure critical for cell replication. This disruption was associated with changes in the expression of genes that regulate cell division, particularly those involved in the “Mitotic Roles of Polo-Like Kinase” pathway. These effects were specific to tumor-targeted frequencies, as non-matching signals had no measurable impact. The study also includes data from two patients with difficult-to-treat brain tumors who received the therapy through compassionate use. One patient with recurrent glioblastoma showed signs of clinical and radiographic improvement after one month of treatment. Another patient with oligodendroglioma tolerated the therapy well and had stable disease during follow-up imaging. Neither patient experienced serious side effects, further supporting the safety of the therapy. “There was evidence of clinical and radiological benefit in a 38-year-old patient with recurrent GB and evidence of safety and feasibility in a 47-year-old patient with oligodendroglioma.” This is the first study to demonstrate that tumor-specific radiofrequency therapy can suppress both tumor growth and cancer stem cells in glioblastoma. Similar results had previously been observed in liver and breast cancers. These findings contribute to the growing body of evidence supporting a new class of systemic, non-toxic cancer therapies. Further clinical trials will be crucial to confirm these results and fully assess the potential of this approach for treating brain cancer. DOI - https://doi.org/10.18632/oncotarget.28770 Correspondence to - Hugo Jimenez - hugo.jimenez@wayne.edu Abstract video - https://www.youtube.com/watch?v=uxYnWcNKYfg Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28770 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, oncology, amplitude-modulated radiofrequency electromagnetic fields, glioblastoma, TheraBionic, CACNA1H, Cav3.2 To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

In this inspiring episode, Dr. Felipe Gálvez-Cancino, group leader at Oxford's Center for Immuno-Oncology, walks us through his team's groundbreaking research on macrophages, T cells, and immune regulation in solid tumors. Tracing his path from early cancer vaccine work to advanced antibody-dependent cellular phagocytosis (ADCP), Felipe shares how his team is working to reprogram tumor-associated macrophages to more efficiently eliminate cancer cells.He explains how regulatory CD4+ T cells suppress both T cell and macrophage responses within tumors and how removing that suppression can supercharge phagocytic function. We also hear how his lab is leveraging mouse models of hepatocellular carcinoma, clinical samples, and modern molecular biology techniques (like in vivo liver transfection and CRISPR-ready plasmid engineering) to study intratumor heterogeneity and antigen spreading.Felipe also reflects on the value of early molecular biology training—like mastering gigapreps—and emphasizes the importance of curiosity, persistence, and collaboration in scientific careers. Whether you're interested in cancer biology, immunotherapy, or just passionate about translating discoveries into new therapies, this episode offers both technical depth and motivational insight. Subscribe to get future episodes as they drop and if you like what you're hearing we hope you'll share a review or recommend the series to a colleague.  Visit the Invitrogen School of Molecular Biology to access helpful molecular biology resources and educational content, and please share this resource with anyone you know working in molecular biology. For Research Use Only. Not for use in diagnostic procedures.

Heal The Soul, Heal The Body: Immersive Reality For Interfaith Rooms Many interfaith rooms in hospitals are either too specific to one religion or not specific enough to feel sacred. Our experts this week discuss how immersive reality and Disney technology can help give patients the religious rooms they crave while fighting for their lives. Glioblastoma: The Aggressive Brain Cancer That Has A Sweet Tooth Glioblastomais an aggressive form of brain cancer that leaves many patients withonly tw years to live, if they're lucky. One obstacle researcherface is understanding how the tumors grow so fast. Our expert explains his breakthrough research on the cancer's metabolic habits and how it'll help increase life expectancy for patients. Medical Notes: Binge-Watching Is Good For Your Brain, How To Detect Cancer At Home, And Breaking Bad Fitness Habits Learn more about your ad choices. Visit megaphone.fm/adchoices

Glioblastoma is an aggressive form of brain cancer that leaves many patients with only two years to live, if they're lucky. One obstacle researchers face is understanding how the tumors grow so fast. Roger Holzberg explains his breakthrough research on the cancer's metabolic habits and how it'll help increase life expectancy for patients. Learn More: https://radiohealthjournal.org/glioblastoma-the-aggressive-brain-cancer-that-has-a-sweet-tooth Learn more about your ad choices. Visit megaphone.fm/adchoices

Summary of the YouTube Video Featuring Brandon McBee on the Strong Dad's PodcastIntroduction and ContextThe video begins with a brief introduction by the Merrill, who reflects on his recent diagnosis of cancer, Glioblastoma. Merrill expresses gratitude for the audience's continued supportand an explanation for the delay in this particular episode. The show features Brandon McBee, an experienced educator and assistant principal at Harrison Junior School in Harrison, Ohio, who shares insights into the importance of father involvement in children's education.Importance of Father's RoleBrandon emphasizes that the presence of a father figure or a positive male role model significantly influences a child's development. He references statistics to underline the negative outcomes for children when fathers are absent, such as increased behavioral problems and lower academic performance. He notes that the role of dads in education is crucial, and their active engagement can make a significant difference in a child's life.Changes in Education Over TimeBrandon discusses how his role in education has evolved over his 15 years in the field, particularly due to the COVID-19 pandemic, which transformed the educational landscape. He shares experiences from his first year in administration when he had to manage contact tracing and other pandemic-related challenges. The conversation touches on the cyclical nature of educational trends, where old strategies re-emerge under new names.Technology in EducationThe discussion highlights the impact of technology on students' learning experiences. Brandon notes that while technology has benefits, over-reliance on it can lead to challenges like cyberbullying and diminished social skills. He advocates for more face-to-face interaction and physical activity, encouraging parents to limit access to devices for young children.The Evolving Role of SchoolsBrandon indicates that while schools have adapted by integrating technology, there is a growing conversation about the need to return to more traditional teaching methods. Educational PhilosophyBrandon reflects on educational reforms, cautioning against the constant changes driven by political agendas. He stresses that while teaching methods may change, the fundamentals of education and human interaction remain constant.Engaging with ChildrenThe discussion pivots towards how fathers can actively engage with their children. Brandon offers practical advice for dads, encouraging them to start small and find common interests to connect with their kids. Navigating ExpectationsBrandon discusses the balance of setting expectations for children. He advocates for clear communication and consistency regarding what is expected from kids in terms of behavior and academic performance, emphasizing the need for flexibility based on individual strengths and weaknesses.Challenges of ParentingThe video addresses the pressures parents face in raising children amidst societal expectations. Brandon reflects on the importance of resilience and teaching children how to handle failure. The Role of LeadershipBrandon shares insights into leadership, both in education and parenting. He encourages dads to model good leadership qualities, such as empathy, understanding, and teamwork. rocksolidfamilies.orgSupport the show#Rocksolidfamilies,#familytherapy,#marriagecounseling,#parenting,#faithbasedcounseling,#counseling,#Strongdads,#coaching,#lifecoach,#lifecoaching,#marriagecoaching,#marriageandfamily,#control,#security,#respect,#affection,#love,#purpose,#faith,#mastersofdisaster,#storms,#disasterrelief,#tornados,#hurricanes,#floods

SOURCES: The Female Family Annihilator - Hannah Scott, Katie Fleming, 2014Why did this TikTok influencer kill her husband and two children? | The IndependentAutopsy Results in Madbury, New Hampshire Deaths Investigation

UK glioblastoma patients face stark choices: NHS treatments or advanced private therapies. Learn more about emerging treatments for this aggressive cancer, the cost of treatment, waiting times, and the outlook for patients. Visit https://gofund.me/c11576b0 to learn about one family's battle for a cure. Asta Pratapaviciene City: Basildon Address: 28 Gilbert Drive Website: https://gofund.me/c11576b0 Email: asta72922@gmail.com

View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter's Weekly Newsletter Edward Chang is a neurosurgeon, scientist, and a pioneering leader in functional neurosurgery and brain-computer interface technology, whose work spans the operating room, the research lab, and the engineering bench to restore speech and movement for patients who have lost these capabilities. In this episode, Edward explains the evolution of modern neurosurgery and its dramatic reduction in collateral damage, the experience of awake brain surgery, real-time mapping to protect critical functions, and the split-second decisions surgeons make. He also discusses breakthroughs in brain-computer interfaces and functional electrical stimulation systems, strategies for improving outcomes in glioblastoma, and his vision for slimmer, safer implants that could turn devastating conditions like ALS, spinal cord injury, and aggressive brain tumors into more manageable chronic illnesses. We discuss: The evolution of neurosurgery and the shift toward minimally invasive techniques [2:30]; Glioblastomas: biology, current treatments, and emerging strategies to overcome its challenges [10:45]; How brain mapping has advanced from preserving function during surgery to revealing how neurons encode language and cognition [16:30]; How awake brain surgery is performed [22:00]; How brain redundancy and plasticity allow some regions to be safely resected, the role of the corpus callosum in epilepsy surgery, and the clinical and philosophical implications of disconnecting the hemispheres [26:15]; How neural engineering may restore lost functions in neurodegenerative disease, how thought mapping varies across individuals, and how sensory decline contributes to cognitive aging [39:15]; Brain–computer interfaces explained: EEG vs. ECoG vs. single-cell electrodes and their trade-offs [48:30]; Edward's clinical trial using ECoG to restore speech to a stroke patient [1:01:00]; How a stroke patient regained speech through brain–computer interfaces: training, AI decoding, and the path to scalable technology [1:10:45]; Using brain-computer interfaces to restore breathing, movement, and broader function in ALS patients [1:28:15]; The 2030 outlook for brain–computer interfaces [1:34:00]; The potential of stem cell and cell-based therapies for regenerating lost brain function [1:38:00]; Edward's vision for how neurosurgery and treatments for glioblastoma, Parkinson's disease, and Alzheimer's disease may evolve by 2040 [1:42:15]; The rare but dangerous risk of vertebral artery dissections from chiropractic neck adjustments and high-velocity movements [1:44:45]; How Harvey Cushing might view modern neurosurgery, and how the field has shifted from damage avoidance to unlocking the brain's functions [1:46:15]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube

Summary of the YouTube Video Featuring Merrill and Andy from Strong Dads and Rock Solid FamiliesIntroduction Update on Merrill's Health•Diagnosis Announcement: Merrill shares that he was diagnosed with glioblastoma on July 23rd, describing it as a severe case with three tumors. The prognosis is uncertain, with varying survival rates depending on treatment efficacy.•Community Support: Merrill expresses deep gratitude for the overwhelming support from the community, including meals, prayers, and financial assistance. He emphasizes the importance of community and church as pillars of support during crises.•Treatment Regimen: Currently undergoing radiation therapy and taking chemotherapy pills, Merrill describes the physical and emotional toll of the treatment, including low energy levels and cognitive challenges.Personal Reflections on Life and Priorities •Emotional Impact: The diagnosis has led Merrill to reassess what is important in life. He stresses the importance of prioritizing relationships, particularly with God, family, and community.•Perspective Shift: Merrill discusses how facing a life-threatening illness has prompted him to reflect deeply on his priorities and what truly matters. He mentions upcoming family events, such as his daughter's wedding, emphasizing the need to cherish these moments.•Faith and Peace: Merrill shares that despite the challenges, he feels a profound sense of peace rooted in his faith. He encourages the audience to consider their relationship with God as a foundational aspect of handling crises.Navigating Relationships and Community •Importance of Relationships: The conversation touches on the significance of nurturing relationships, with God at the center. Merrill highlights how a strong faith can enhance other relationships, particularly with one's spouse.•Joint Efforts in Communication: Merrill and Andy emphasize the need for couples to pray together and communicate effectively, which fosters unity and alignment in facing challenges.Living with Purpose and Prioritizing Faith•Facing Mortality: Merrill reflects on the idea of death and his acceptance of it, grounded in his Christian faith. He expresses anticipation for what lies beyond this life, revealing a lack of fear associated with dying.•Bucket List and Regrets: The discussion shifts towards pursuing dreams and aspirations without fear of failure. Merrill encourages taking risks and being obedient to God's calling, further illustrating this point by discussing his decision to start Rock Solid Families.•Prayer as Communication: Merrill discusses how prayer is not merely about asking for things but about building a relationship with God. He encourages wrestling with God in prayer as a means to deepen that relationship.Conclusion and Call to Action •Final Thoughts: Merrill ends with an encouragement to prioritize faith and community, urging listeners to not take their relationships for granted. He expresses hope that his experience can inspire others to live intentionally.Support the show#Rocksolidfamilies,#familytherapy,#marriagecounseling,#parenting,#faithbasedcounseling,#counseling,#Strongdads,#coaching,#lifecoach,#lifecoaching,#marriagecoaching,#marriageandfamily,#control,#security,#respect,#affection,#love,#purpose,#faith,#mastersofdisaster,#storms,#disasterrelief,#tornados,#hurricanes,#floods

Duke University's Preston Robert Tisch Brain Tumor Center will soon offer new mental and emotional support for its patients, their families and their caregivers, all thanks to the donation of a former patient's daughter. Durham native Rebecca Feinglos donated $250,000 to create the Susan & Mark Feinglos Grief initiative in honor of her parents. Her mother died after being diagnosed with Glioblastoma, the most deadly for of brain cancer when she was 13 years old. Her father died from a sudden illness in 2020. WRAL news reporter Grace Holland shares how Feinglos hopes the new program can help all those impacted by the cancer - from patients to family and even medical professionals. 

In this episode, editor in chief Joseph E. Safdieh, MD, FAAN, highlights articles about a promising blood test to distinguish Parkinson's disease from dementia with Lewy bodies, how CAR T-cell therapies are showing potential for patients with glioblastoma, and a new wireless electroencephalogram device that can even monitor young children with epilepsy.

Glioblastoma diagnoses affect thousands of UK families annually, but many don't realise the full spectrum of support resources available beyond standard NHS care. From specialised treatments to community fundraising, families are discovering new pathways to hope and healing. To learn more, visit: https://gofund.me/c11576b0 Asta Pratapaviciene City: Basildon Address: 28 Gilbert Drive Website: https://gofund.me/c11576b0 Email: asta72922@gmail.com

My World Just Flipped  - Glioblastoma - Ep 329In this heartfelt YouTube video, Merrill Hutchinson, the host of RockSolid Families and Strong Dads, shares a personal update about his health journey. The video serves as both an introduction to his current situation and a reflection on life's deeper meanings amidst adversity.Key Points and Flow:1. Introduction and Context:• Merrill welcomes viewers and explains why he is combining two shows into one episode. He mentions feeling unwell for the past month and hints at a significant life change.2. Health Concerns:• He recounts how in mid-July, he began experiencing unusual symptoms like confusion and impaired balance. Despite initially dismissing these signs, he eventually consulted his doctor.3. Diagnosis:• On July 23rd, Merrill received a troubling diagnosis: glioblastoma, a severe and terminal brain cancer. He shares the stark reality of his prognosis, facing multiple brain surgeries and the emotional turmoil that has ensued.4. Emotional Response:• Merrill discusses the emotional rollercoaster he experienced following the diagnosis, feeling overwhelmed yet determined to use his situation for a greater purpose. He emphasizes the importance of sharing his story, not for sympathy but to inspire and encourage others.5. Surgery and Treatment:• He details his surgeries, noting their success while acknowledging the aggressive nature of the cancer. Merrill prepares to begin chemotherapy and radiation, hoping for stabilization of his condition.6. Spiritual Reflection:• Merrill reflects on his faith, quoting John 14:6, which has influenced his understanding of control and surrender to God. He expresses the importance of humility in facing life's challenges and encourages viewers to seek a godly perspective over a self-centered one.7. Family and Celebrations:• He shares personal anecdotes about his family, highlighting both the struggles and joys, like an upcoming wedding in the family, which he views as a blessing and a reason to celebrate life.8. Encouragement for Viewers:• Merrill concludes with a message to viewers about the significance of community support and the need to prioritize relationships and kindness in difficult times. He expresses gratitude for the support he and his family have received.9. Closing Thoughts:• He wraps up by thanking his sponsors and the community for their support, reiterating his intent to share updates and insights as he navigates this challenging journey.Support the show#Rocksolidfamilies, #familytherapy, #marriagecounseling, #parenting, #faithbasedcounseling, #counseling, #Strongdads, #coaching, #lifecoach, #lifecoaching, #marriagecoaching, #marriageandfamily, #control, #security, #respect, #affection, #love, #purpose, #faith, #affairs, #infidelity

My World Just Flipped  - Glioblastoma - Ep 329In this heartfelt YouTube video, Merrill Hutchinson, the host of RockSolid Families and Strong Dads, shares a personal update about his health journey. The video serves as both an introduction to his current situation and a reflection on life's deeper meanings amidst adversity.Key Points and Flow:1. Introduction and Context:• Merrill welcomes viewers and explains why he is combining two shows into one episode. He mentions feeling unwell for the past month and hints at a significant life change.2. Health Concerns:• He recounts how in mid-July, he began experiencing unusual symptoms like confusion and impaired balance. Despite initially dismissing these signs, he eventually consulted his doctor.3. Diagnosis:• On July 23rd, Merrill received a troubling diagnosis: glioblastoma, a severe and terminal brain cancer. He shares the stark reality of his prognosis, facing multiple brain surgeries and the emotional turmoil that has ensued.4. Emotional Response:• Merrill discusses the emotional rollercoaster he experienced following the diagnosis, feeling overwhelmed yet determined to use his situation for a greater purpose. He emphasizes the importance of sharing his story, not for sympathy but to inspire and encourage others.5. Surgery and Treatment:• He details his surgeries, noting their success while acknowledging the aggressive nature of the cancer. Merrill prepares to begin chemotherapy and radiation, hoping for stabilization of his condition.6. Spiritual Reflection:• Merrill reflects on his faith, quoting John 14:6, which has influenced his understanding of control and surrender to God. He expresses the importance of humility in facing life's challenges and encourages viewers to seek a godly perspective over a self-centered one.7. Family and Celebrations:• He shares personal anecdotes about his family, highlighting both the struggles and joys, like an upcoming wedding in the family, which he views as a blessing and a reason to celebrate life.8. Encouragement for Viewers:• Merrill concludes with a message to viewers about the significance of community support and the need to prioritize relationships and kindness in difficult times. He expresses gratitude for the support he and his family have received.9. Closing Thoughts:• He wraps up by thanking his sponsors and the community for their support, reiterating his intent to share updates and insights as he navigates this challenging journey.Support the show#Rocksolidfamilies,#familytherapy,#marriagecounseling,#parenting,#faithbasedcounseling,#counseling,#Strongdads,#coaching,#lifecoach,#lifecoaching,#marriagecoaching,#marriageandfamily,#control,#security,#respect,#affection,#love,#purpose,#faith,#mastersofdisaster,#storms,#disasterrelief,#tornados,#hurricanes,#floods

Neurologist Michelle Monje studies the close relationship between cancer and the nervous system, particularly in an aggressive brain cancer that often strikes in childhood. Her research shows that the cancer cells are electrically integrated into the brain itself and these connections actually help the cancer to grow. Monje and collaborators have now developed an immunotherapy that has shown great promise in mice and early human trials. One patient had a “complete response” and is cancer-free four years after treatment, Monje tells host Russ Altman on this episode of Stanford Engineering's The Future of Everything podcast.Have a question for Russ? Send it our way in writing or via voice memo, and it might be featured on an upcoming episode. Please introduce yourself, let us know where you're listening from, and share your question. You can send questions to thefutureofeverything@stanford.edu.Episode Reference Links:Stanford Profile: Michelle MonjeConnect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>> Twitter/X / Instagram / LinkedIn / FacebookChapters:(00:00:00) IntroductionRuss Altman introduces guest Michelle Monje, a professor of pediatric neurology at Stanford University.(00:03:39) Focus on Cancer ResearchMonje's clinical observations led to exploring cancer-neuron interactions.(00:05:28) Neurons and Glial CellsThe role of neurons and glial cells in brain function and disease.(00:08:32) Gliomas in ChildrenAn overview of gliomas and their origins in glial precursor cells.(00:10:12) Rethinking Brain Cancer BehaviorHow gliomas don't just grow—they integrate with brain circuits.(00:14:49) Mechanisms of Tumor GrowthTwo primary mechanisms by which cancer exploits the nervous system.(00:16:32) Synaptic Integration of Cancer CellsThe discovery that glioma cells form synapses with neurons.(00:20:06) CAR T-Cell TherapyAdapting CAR T-cell immunotherapy to target brain tumors.(00:22:52) Targeting GD2 AntigenIdentification of a surface marker enables precision CAR T-cell therapy.(00:24:35) Immune Access to the BrainThe ability of CAR T-cells to reach the brain, despite prior understanding.(00:26:16) First Clinical Trial ResultsThe significant tumor reduction and response from CAR T-cell therapy.(00:28:21) Combined TherapiesPairing immune therapy with neural signaling blockers for better outcomes.(00:30:35) Conclusion Connect With Us:Episode Transcripts >>> The Future of Everything WebsiteConnect with Russ >>> Threads / Bluesky / MastodonConnect with School of Engineering >>>Twitter/X / Instagram / LinkedIn / Facebook

September 2025 Journal Club Podcast Title: Ventricular Entry During Glioblastoma Resection is Associated With Reduced Survival and Increased Risk of Distant Recurrence To read journal article: https://journals.lww.com/neurosurgery/fulltext/2025/09000/ventricular_entry_during_glioblastoma_resection_is.10.aspx Author: Neslihan Gecici and Pascal Zinn Guest Faculty: Bryan Choi Moderator: Alexander Himstead Committee Co-Chair: Kimberly Hoang

Medical fundraising has become essential for UK glioblastoma patients seeking private treatment beyond NHS options. Specialized therapies cost £50,000-£150,000, driving families to crowdfunding platforms for life-saving care access. To learn more, visit: https://gofund.me/c11576b0 Asta Pratapaviciene City: Basildon Address: 28 Gilbert Drive Website: https://gofund.me/c11576b0 Email: asta72922@gmail.com

The role of neuronal influences on cancer pathogenesis and progression is increasingly appreciated in the nervous system. Neurons have been shown to enhance the proliferation and migration of gliomas, a glial-derived tumor of the CNS, via diffusible paracrine factors or synaptic inputs onto tumor cells. In glioblastomas, a highly aggressive glioma, mostly glutamatergic inputs have been identified. While the potential for glioblastomas to receive projections from neurons of other neurotransmitter subtypes, such as from cholinergic neurons, has recently been discovered in xenotransplantation models, whether synapses can form between human cholinergic neurons and glioblastoma cells and consequences of these inputs and other non-synaptic mechanisms are still unknown.   Human induced pluripotent stem cell-based models have been emerging as a powerful platform for studying human-specific disease mechanisms. Today's guests developed a co-culture model for the study of neuron-tumor interactions by combining patient derived glioblastoma organoids and hiPSC-derived cholinergic neurons. They will discuss their recent findings and what it means for understanding and potentially treating a tumor for which there is no known cure. GuestsGuo-li Ming, MD, PhD, Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of PennsylvaniaHongjun Song, PhD, Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, University of Pennsylvania Yusha Sun, Neuroscience Graduate Group, Perelman School of Medicine, University of PennsylvaniaHostJanet Rossant, Editor-in-Chief, Stem Cell Reports and The Gairdner FoundationSupporting ContentPaper link:  Cholinergic neuron-to-glioblastoma synapses in a human iPSC-derived co-culture model, Stem Cell ReportsAbout Stem Cell ReportsStem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.X: @StemCellReportsAbout ISSCRWith nearly 5,000 members from more than 80 countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.ISSCR StaffKeith Alm, Chief Executive OfficerYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsMegan Koch, Senior Marketing ManagerJack Mosher, Scientific DirectorHunter Reed, Senior Marketing Coordinator

Glioblastoma affects around 3,000 people in the UK each year. Here's what you need to know about treatment options, costs, and what families are doing when the NHS can't cover their treatment. Visit https://gofund.me/c11576b0 to learn how one family is funding their battle against cancer. Asta Pratapaviciene City: Basildon Address: 28 Gilbert Drive Website: https://gofund.me/c11576b0 Email: asta72922@gmail.com

Good morning from Pharma and Biotech Daily: the podcast that gives you only what's important to hear in Pharma and Biotech world. BioNTech is focusing on infectious diseases as vaccine rates drop, with expectations that the US COVID-19 vaccination rate will decrease slightly. Glioblastoma research is seeing increased funding and interest from companies like Merck and Jazz Pharmaceuticals. The FDA's rejection of Replimmune's melanoma drug, despite staff consensus, has caused a drop in the company's stock. Sarepta and Capricor learned of regulatory decisions through media leaks, causing confusion for patients and families. Trilink Biotechnologies offers process development services for nucleic acid therapeutic development. Lotte Biologics is expanding globally, Allogene is discontinuing an immunosuppressive antibody after a patient death, and NIH funding cuts are impacting biotech. Pharmas are increasing investment in AI despite challenges in the industry. Trump urges pharma companies to address drug pricing, while Merck plans to cut 6,000 jobs to save $3 billion.

Until only recently, treating Glioblastoma brain cancer with chemotherapy has not been achievable due to the blood brain barrier.  In today's Bindwaves episode, Dr. Michael Canney walks us through how Carthera developed a revolutionary method to deliver therapeutics to the brain utilizing an ultrasound system.  It is well known that the survival rate for Glioblastoma is 1 to 2 years.  Surgery tends to be the primary means to combat this horrible disease.  To improve these odds, an ultrasound implant is placed in the brain after the surgeon removes the tumor.  This implant, or mesh, contains an ultrasound transducer, which when activated during chemo treatments, disrupts the blood brain barrier thus allowing therapeutics to attach to the cancer cells.   Join us as Dr. Canney eloquently discusses the history of this treatment, Phase 1 and Phase 2 results, and their hopes for the Phase 3 trial. Support the showNew episodes drop every other Thursday everywhere you listen to podcasts.

Anuschka was reborn August 23, 2017 when she was diagnosed with Glioblastoma (GBM) Grade 4 Brain Cancer. After a year and a half of conventional treatments including radiation, chemotherapy, and Novocure Optune, along with a ton of simultaneous non-conventional treatments, including energy healing, subconscious mind reprogramming, radically changing her diet to organic vegan, following her intuition, deepening her spiritual connection, and more, Anuschka is now healed, cancer free, and pregnant with one of the frozen embryos before she started radiation!  Anuschka believes everyone has the ability to heal from within when they find a strong reason to live, balance their MIND BODY SPIRIT, and specifically release suppressed emotions. Connect with Anushka: - Facebook: https://www.facebook.com/HealingWithAnuschka - Instagram: https://www.instagram.com/healing.with.anuschka - LinkedIn: https://www.linkedin.com/in/anuschka - Linktree: https://linktr.ee/healingwithanuschka - YouTube: https://www.youtube.com/healingwithanuschka _____________ To learn more about the 10 Radical Remission Healing Factors, connect with a certified RR coach or join a virtual or in-person workshop visit www.radicalremission.com. To watch Episode 1 of the Radical Remission Docuseries for free, visit our YouTube channel here.  To purchase the full 10-episode Radical Remission Docuseries visit Hay House Online Learning. To learn more about Radical Remission health coaching with Liz or Karla, Click Here Follow us on Social Media: Facebook  Instagram YouTube ____________ Thank you to our friends from The Healing Oasis for sponsoring this episode of the podcast.  The Healing Oasis is a first of its kind in beautiful British Columbia, Canada where we encourage the body to heal from cancer using alternative therapies & cancer fighting meals at a wellness retreat center in nature. Our top naturopathic cancer doctor will prescribe a protocol tailored specifically for you. There's no place quite like it. Start your healing journey today! Learn More about The Healing Oasis by visiting these links: Website   Testimonials Video Overview

For many families facing glioblastoma, the limited NHS options prompt a search beyond conventional care. Private clinics offering experimental treatments can bring hope, but also hefty costs and tough decisions. Learn more about what you should know before going down that road. Visit https://gofund.me/c11576b0 Asta Pratapaviciene City: Basildon Address: 28 Gilbert Drive Website: https://gofund.me/c11576b0 Email: asta72922@gmail.com

Dr. Sandra Silberman, Chief Medical Officer at CNS Pharmaceuticals, has developed new therapies for glioblastoma that can cross the blood-brain barrier to reach brain tumors. Their lead drug candidates have been modified to slip into the membranes to inhibit tumor growth and attack the cancer cells. The anthracycline-based and taxane-based drugs are showing efficacy in clinical trials and are not showing the cardiotoxicity associated with anthracyclines. Sandra explains, "Anthracyclines are characteristically cardiotoxic. And we have just conducted a study of over 160 patients who have received this, and some of them for quite a long period of time. And we have not seen any cardiotoxicity. So we have one of the anthracyclines that is the first to actually cross the blood-brain barrier without any help from other mechanisms, and it also doesn't cause cardiotoxicity. So we have a really open field to be able to further develop this drug. And we know that this drug, based on all of our preclinical studies, is very effective against glioma cells." "This is to the great credit of the chemists that we've been working with. Can I develop a compound that can not be a substrate for this, so it can't even bind to this efflux transporter and can slip by? But not only that, can it be lipophilic, meaning it can get through all those membranes, and it can be something that leaks into the brain itself. So the two molecules that we have are not substrates for these multidrug-resistant transporters. They're also very highly lipophilic, meaning they're very oily. And so I guess this has two meanings to it, but they're oily and then they slip into the brain and are able to do what they're supposed to be doing, which is the inhibition of tumor growth and killing the tumor cells." #CNSPharma #Glioblastoma ##BrainCancer #BloodBrainBarrier #NeuroOncology #CancerResearch #DrugDevelopment #BrainTumor cnspharma.com  Download the transcript here

Dr. Sandra Silberman, Chief Medical Officer at CNS Pharmaceuticals, has developed new therapies for glioblastoma that can cross the blood-brain barrier to reach brain tumors. Their lead drug candidates have been modified to slip into the membranes to inhibit tumor growth and attack the cancer cells. The anthracycline-based and taxane-based drugs are showing efficacy in clinical trials and are not showing the cardiotoxicity associated with anthracyclines. Sandra explains, "Anthracyclines are characteristically cardiotoxic. And we have just conducted a study of over 160 patients who have received this, and some of them for quite a long period of time. And we have not seen any cardiotoxicity. So we have one of the anthracyclines that is the first to actually cross the blood-brain barrier without any help from other mechanisms, and it also doesn't cause cardiotoxicity. So we have a really open field to be able to further develop this drug. And we know that this drug, based on all of our preclinical studies, is very effective against glioma cells." "This is to the great credit of the chemists that we've been working with. Can I develop a compound that can not be a substrate for this, so it can't even bind to this efflux transporter and can slip by? But not only that, can it be lipophilic, meaning it can get through all those membranes, and it can be something that leaks into the brain itself. So the two molecules that we have are not substrates for these multidrug-resistant transporters. They're also very highly lipophilic, meaning they're very oily. And so I guess this has two meanings to it, but they're oily and then they slip into the brain and are able to do what they're supposed to be doing, which is the inhibition of tumor growth and killing the tumor cells." #CNSPharma #Glioblastoma ##BrainCancer #BloodBrainBarrier #NeuroOncology #CancerResearch #DrugDevelopment #BrainTumor cnspharma.com Listen to the podcast here  

Grammy-nominated singer, songwriter and pianist Regina Spektor grew up in Soviet Russia, so when she moved to the Bronx with her family in 1990, American food was a bit of a culture shock. Cereal! Oranges! Chocolate pudding cups! It was all brand-new! Regina shares a handful of her family’s immigration eating stories. When in doubt, order the soup! That’s what Regina does. She tells host Rachel Belle about her (nearly) lifelong love of soup, what caused her to rebel against it in high school and why the simplest of broths would be her last meal. Cookbook author Caroline Wright never set out to have a career in soup, but a terminal cancer diagnosis resulted in a soup club, two vegan soup cookbooks and the title of Seattle Soup Lady. She tells Rachel her story. Watch Rachel’s Cascade PBS TV show The Nosh with Rachel Belle! Season 2 out now! Sign up for Rachel’s new (free!) Cascade PBS newsletter for more food musings! Follow along on Instagram! Order Rachel’s cookbook Open Sesame. Support the show: http://rachelbelle.substack.com/See omnystudio.com/listener for privacy information.

In this episode, we visit KU Leuven in Belgium to explore GLIOMATCH, a groundbreaking European research initiative working to improve outcomes for adults and children with glioblastoma through collaboration across neurosurgery, oncology, immunology, and spatial omics. We speak with the experts leading this innovative work. Frederik De Smet, Professor and GLIOMATCH Project Coordinator at KU Leuven, outlines the vision for the project and how it brings together multiple disciplines to tackle one of the most challenging forms of cancer. Steven De Vleeschouwer, MD, PhD, Neurosurgeon and expert in immunotherapy trials, shares how surgical intervention plays a key role not only in treatment but also in advancing research. Paul M. Clement, MD, Medical Oncologist specializing in adult neuro-oncology, discusses the complexities of post-surgical care and how GLIOMATCH is helping improve decision-making. Sandra Jacobs, MD, Pediatric Neuro-Oncologist, highlights the unique challenges in treating children and the need for tailored research approaches. Thierry Voet, PhD, Chair of the Leuven Institute for Single-Cell Omics, explains how cutting-edge spatial omics is transforming our understanding of glioblastoma biology. Abhishek D. Garg, PhD, Tumor Immunology Specialist, shares how data science and deep immune profiling are driving new insights into overcoming immunotherapy resistance. GLIOMATCH is a testament to the power of collaboration in pushing the boundaries of glioblastoma research and offering hope for patients and families worldwide. This work is funded by the European Union. Views and opinions expressed are those of the author(s) only and do not necessarily reflect those of the European Union or the European Health and Digital Executive Agency (HaDEA). Neither the European Union nor the granting authority can be held responsible for them. This work is also supported by Innovate UK [grant number 10113516] and the Swiss State Secretariat for Education, Research and Innovation (SERI) under the contract number 23.00607. Learn more at www.gliomatch.eu This episode is intended for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for guidance specific to your health or treatment plan.

When Rebecca was 27 years old, her mom was diagnosed with glioblastoma. It turned her life upside down. And it wasn't until 15 years and 4 kids later that it righted itself. She herself was diagnosed with glioblastoma, given the same bleak prognosis as her mother of 12-15 months and limited treatment options.  Rebecca's entire adult life had been ruled by anxiety but something happened during her surgery that changed her perspective. She felt an overwhelming sense of peace and deep knowing that she was on the path she was meant to take. This experience had a huge impact. Rebecca bravely tried a new treatment in Germany, threw away her chemo and used food, fitness and mindset to save her life. Since then, Rebecca has tried to raise her children with the empowering message that you can control your own health by making good choices. Rebecca has had no evidence of disease for over 7 years. www.rebeccadevine.com instagram: @thatbrainyblonde podcast: The Brainy Blonde Podcast ____________________ To learn more about the 10 Radical Remission Healing Factors, connect with a certified RR coach or join a virtual or in-person workshop visit www.radicalremission.com. To watch Episode 1 of the Radical Remission Docuseries for free, visit our YouTube channel here.  To purchase the full 10-episode Radical Remission Docuseries visit Hay House Online Learning. To learn more about Radical Remission health coaching with Liz or Karla, Click Here Follow us on Social Media: Facebook  Instagram YouTube ________________________ Thank you to our friends from The Healing Oasis for sponsoring this episode of the podcast.  The Healing Oasis is a first of its kind in beautiful British Columbia, Canada where we encourage the body to heal from cancer using alternative therapies & cancer fighting meals at a wellness retreat center in nature. Our top naturopathic cancer doctor will prescribe a protocol tailored specifically for you. There's no place quite like it. Start your healing journey today! Learn More about The Healing Oasis by visiting these links: Website   Testimonials Video Overview

Join Michael and mom Ashlee as they talk to Michael Canney, Ph.D., who is leading an exciting Phase 3 clinical trial that holds the promise of reshaping brain cancer treatment in particular in glioblastoma. This trial is testing a new surgical implant using ultrasound to enhance chemotherapy effectiveness against brain tumors, in particular because of the blood/brain barrier. Mike is at the forefront of efforts at 40 clinical sites worldwide, 20 in the US, working to push the boundaries in brain cancer treatments. The conversation takes a personal turn, as always with Michael and mom :)find out more about this phase 3 clinical trial for Glioblastoma:https://sonobird.eu/More info about Carthera:https://carthera.eu/More about Michael Canney on Linked In:https://www.linkedin.com/in/michael-canney-ph-d-42457b5/

Researchers at Brown University have developed a combination treatment that significantly increases survival in mice with glioblastoma (GBM), a highly aggressive and treatment-resistant brain cancer. The approach uses a new class of drugs called imipridones along with radiation therapy and standard chemotherapy. This triple therapy, known as IRT, was recently detailed in a study published in Oncotarget. Understanding Glioblastoma and the Need for Better Therapies Glioblastoma is the most common and aggressive malignant brain tumor in adults. It grows quickly and is difficult to treat, often leading to poor outcomes. Most patients survive less than 15 months after diagnosis, even when treated with surgery, radiation, and the chemotherapy drug temozolomide (TMZ). This treatment may slow the disease, but it does not typically stop it. Full blog - https://www.oncotarget.org/2025/06/04/experimental-triple-therapy-improves-survival-in-glioblastoma-mouse-model/ Paper DOI - https://doi.org/10.18632/oncotarget.28707 Correspondence to - Wafik S. El-Deiry - wafik@brown.edu Video short - https://www.youtube.com/watch?v=Q_mXy8mana0 Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28707 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, glioblastoma multiforme, IDH, ONC201, ONC206, MGMT, temozolomide, radiotherapy To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

In this episode of the Osteopathic Manipulative Medicine Podcast, we discuss the metabolic approach to treating cancer with Alicia Hickson, a physician assistant and certified functional medicine provider and Founder of Rayma Health.  The conversation emphasizes the significance of addressing the root causes of chronic illnesses and the relationship between lifestyle choices and cancer development. In this conversation, Alicia   emphasizes the synergy between different treatment modalities, particularly the role of nutrition and the ketogenic diet in managing cancer. Alicia also highlights the significance of patient advocacy and collaboration among healthcare providers to improve patient outcomes and quality of life during treatment.Resources: --> Suboccipital Release and Cortisol Levels--> Clinical Research Framework Proposal for Ketogenic Metabolic Therapy in Glioblastoma--> A Parent's Guide to Childhood Cancer: Supporting Your Child with Integrative Therapies Based on a Metabolic ApproachAlicia Hickson PA-C: info@raymahealth.comONMM Podcast: onmmpodcast@gmail.com

Being a caregiver for someone with brain cancer is emotionally and physically exhausting, but you don't have to navigate it alone. In this episode of Caregiver 101, we sit down with Sylvia's husband as he opens up about what it's really like to support a loved one through a brain cancer diagnosis. From planning future trips to leaning on faith and community, this conversation is filled with hope, resilience, and practical advice.   What you'll learn:• How to maintain normalcy after a brain cancer diagnosis• The importance of community, faith, and medical teams• Tips for emotional well-being, for both patients and caregivers• Real stories from families walking this path Host:Johanna GomezAward-Winning Host & Journalist Expert:Yazmin Odia, M.D.Chief of Neuro-OncologyBaptist Health Miami Cancer Institute Caregiver: Martin Hiriart (Husband of Silvia Fajardo-Hiriart)

Broadcast from KSQD, Santa Cruz on 5-22-2025: Dr. Dawn explores groundbreaking cancer research using high-throughput "digital twin" analysis to reverse colon cancer cells back to normal states, identifying three master molecular switches that can induce normal cell differentiation without killing the cancer cells, thus avoiding traditional chemotherapy side effects. She discusses remarkable results from Memorial Sloan Kettering showing 80% of patients with mismatch repair deficient tumors, including all 49 rectal cancer patients, saw complete tumor disappearance after six months of dostarlimab immunotherapy, with no recurrence at five years and minimal side effects. The program covers innovative CRISPR applications, including targeting previously "undruggable" cancer mutations like KRAS and BRAF by selectively degrading mutant RNA messages while preserving healthy genes, offering unprecedented precision in cancer treatment. Dr. Dawn explains a clever immunotherapy approach that disguises tumors as pig organs using Newcastle disease virus carrying alpha-gal enzyme, tricking the immune system into mounting fierce attacks against cancer cells, showing promising results in both monkey and human trials. She describes fascinating research using cryoshocked tumor cells as Trojan horses, where liquid nitrogen-treated cancer cells carrying CRISPR gene editing tools directly seek out tumors, offering superior targeting compared to injecting CRISPR. The show reveals how cancers create protective acid walls around themselves to repel immune cells, with individual cancer cells pumping lactic acid away from the tumor center to form pH 5.3 barriers that kill attacking CD8 T cells within hours. Dr. Dawn discusses breakthrough mRNA cancer vaccines for glioblastoma using patients' own tumor cells, showing rapid immune system activation within 48 hours and extending survival in both dogs and humans with this aggressive brain cancer. She explores the "flower code" mechanism where cancer cells gaslight healthy cells through epigenetic manipulation, expressing dominant "flower win" codes to overpower normal cells expressing "flower lose" codes in biological turf wars. The program addresses systemic problems in cancer classification, explaining how organ-based categorization delays access to effective treatments, with patients waiting years for drugs that could help based on molecular profiles rather than tumor location. Dr. Dawn concludes by highlighting medical discrimination against people with Duffy null phenotype, primarily affecting African Americans, whose naturally lower neutrophil counts lead to reduced chemotherapy doses and excluded clinical trial participation despite no increased infection risk.

Broadcast from KSQD, Santa Cruz on 5-22-2025: Dr. Dawn explores groundbreaking cancer research using high-throughput "digital twin" analysis to reverse colon cancer cells back to normal states, identifying three master molecular switches that can induce normal cell differentiation without killing the cancer cells, thus avoiding traditional chemotherapy side effects. She discusses remarkable results from Memorial Sloan Kettering showing 80% of patients with mismatch repair deficient tumors, including all 49 rectal cancer patients, saw complete tumor disappearance after six months of dostarlimab immunotherapy, with no recurrence at five years and minimal side effects. The program covers innovative CRISPR applications, including targeting previously "undruggable" cancer mutations like KRAS and BRAF by selectively degrading mutant RNA messages while preserving healthy genes, offering unprecedented precision in cancer treatment. Dr. Dawn explains a clever immunotherapy approach that disguises tumors as pig organs using Newcastle disease virus carrying alpha-gal enzyme, tricking the immune system into mounting fierce attacks against cancer cells, showing promising results in both monkey and human trials. She describes fascinating research using cryoshocked tumor cells as Trojan horses, where liquid nitrogen-treated cancer cells carrying CRISPR gene editing tools directly seek out tumors, offering superior targeting compared to injecting CRISPR. The show reveals how cancers create protective acid walls around themselves to repel immune cells, with individual cancer cells pumping lactic acid away from the tumor center to form pH 5.3 barriers that kill attacking CD8 T cells within hours. Dr. Dawn discusses breakthrough mRNA cancer vaccines for glioblastoma using patients' own tumor cells, showing rapid immune system activation within 48 hours and extending survival in both dogs and humans with this aggressive brain cancer. She explores the "flower code" mechanism where cancer cells gaslight healthy cells through epigenetic manipulation, expressing dominant "flower win" codes to overpower normal cells expressing "flower lose" codes in biological turf wars. The program addresses systemic problems in cancer classification, explaining how organ-based categorization delays access to effective treatments, with patients waiting years for drugs that could help based on molecular profiles rather than tumor location. Dr. Dawn concludes by highlighting medical discrimination against people with Duffy null phenotype, primarily affecting African Americans, whose naturally lower neutrophil counts lead to reduced chemotherapy doses and excluded clinical trial participation despite no increased infection risk.

Scientists have engineered small, targeted proteins that can penetrate brain cancer cells and prevent them from invading healthy tissue, offering a promising new approach to treating glioblastoma multiforme (GBM), one of the deadliest forms of brain cancer. This strategy was developed by researchers at the University of Nevada, Reno, and published recently in Oncotarget. The Challenge of Treating Glioblastoma Multiforme Glioblastoma is an aggressive and fast-growing brain tumor that infiltrates healthy brain tissue, making complete surgical removal nearly impossible. Standard treatments like chemotherapy and radiation can slow its growth but rarely prevent it from returning. One major reason for this invasiveness is a group of enzymes known as matrix metalloproteinases (MMPs), which break down surrounding tissue to allow cancer cells to spread. Among these, MMP-9 plays a particularly important role in driving tumor progression and resisting existing therapies. Attempts to block MMPs using small-molecule drugs have failed in clinical trials due to problems like poor selectivity and harmful side effects. Researchers have been searching for safer, more targeted methods to interfere with these enzymes and limit glioblastoma's spread. The Study: Engineered Proteins to Inhibit Tumor Invasion In the study called “Effect of TIMPs and their minimally engineered variants in blocking invasion and migration of brain cancer cells,” researchers Elham Taheri and Maryam Raeeszadeh-Sarmazdeh investigated tissue inhibitors of metalloproteinases (TIMPs), which are natural blockers of MMPs, and their engineered modified versions made to work better. Specifically, the team studied TIMP-1, TIMP-3, along with two engineered molecules, mTC1 and mTC3, in laboratory cell models of GBM. Full blog - https://www.oncotarget.org/2025/05/21/engineered-proteins-show-promise-in-stopping-glioblastoma-invasion/ Paper DOI - https://doi.org/10.18632/oncotarget.28691 Correspondence to - Maryam Raeeszadeh-Sarmazdeh - maryamr@unr.edu Video short - https://www.youtube.com/watch?v=tdBlkOX50D8 Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28691 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, TIMP minimal variants, glioblastoma multiforme (GBM), brain cancer, MMP inhibitors To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM

From Brain Tumor to Bold Faith: Karen's Journey Through Surgery, Glioblastoma & God's Grace In this moving episode of the Fast to Faith Podcast, Karen Bartram shares her unbelievable story—from a small limp and fine motor issues to a devastating diagnosis of a grade 4 glioblastoma. What began as a suspicion of a pinched nerve turned into an emergency room visit, brain surgery, and a life-changing faith journey.Karen walks us through her awake craniotomy, the moments of fear and surrender, and how years of prioritizing her health and spiritual growth prepared her for this unexpected battle. She opens up about combining conventional treatment with holistic healing, and the role prayer, perseverance, and community have played in her resilience. If you've ever wondered where God is in your pain, Karen's story is proof He's been preparing you all along.If you liked this episode, watch it on YouTube!

Dr. Doug Burton refuses to let brain cancer define his days. With unwavering courage, he's embracing every moment, determined to make the most of his time. Now, he's opening up about the groundbreaking treatments that are giving him more chances to laugh, love, and create lasting memories with his family.

Season 4 of Glioblastoma aka GBM kicks off Brain Tumor Awareness Month with a closer look at CeGaT, a genetic diagnostics company based in Tübingen, Germany. Founded in 2009 by Dr. Saskia Biskup and Dirk Biskup, CeGaT focuses on identifying rare diseases and tumor-specific mutations through advanced sequencing technologies. In this episode, we speak with Dr. Biskup and Florian Battke, Head of Research & Development, about what genetic sequencing is, how it's used in the context of brain tumors, and what they see as the next frontier for diagnosing and treating diseases like glioblastoma. We discuss how long-read sequencing may offer greater accuracy in identifying genetic changes and what that could mean for patients navigating difficult diagnoses. This episode explores the broader role that genomics can play in brain cancer research and the questions still left to answer as science continues to evolve. To learn more about the work CeGaT is doing, visit them online at https://cegat.com/ This episode is intended for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider for guidance specific to your health or treatment plan.

Thank you for joining me for the final bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  I'll be completing the series today with a wrap-up about the ministry which developed out of Hannah's homegoing.   As always, my desire is to give glory to God and point listeners to hope in Jesus along the way.  I'm so grateful you've joined me over this past year … Your listens and your kind comments have been a blessing to my heart. Click HERE for more information about the While We're Waiting ministry or to register for one of our free retreats.  We'd love to have the opportunity to serve you at an event!I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

A friend of ours got us connected with an architect who donated his time and drew up a plan for our dream retreat center.  The facility would incorporate the existing house, adding a large dining room, a commercial kitchen, and ten private guest rooms, each with its own bathroom.  No more bunk beds with creaky plastic mattresses or shared bathrooms!  This gentleman created a beautiful concept drawing and presented it to us one snowy Sunday afternoon.  Then he told us the estimated cost ... One MILLION dollars!  We had $3,000 in our While We're Waiting bank account.  Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way.  I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

For three years, we had wonderful bereaved-parent retreats at Family Farm.  As awareness began to grow about the ministry via word-of-mouth, internet searches, and our Facebook presence, our waiting lists also began to grow.  Even with adding more retreat dates at other locations, we could no longer keep up with the demand for these events.And as wonderful as Family Farm is, it was not an ideal location for the types of retreats we were hosting.  After all, it was a children's camp ... complete with bunk rooms filled with bunk beds.  Definitely not ideal for a grieving parent retreat.  Family Farm is also a very busy place, and was only available to us twice a year.So we began to consider some other options.  The ultimate solution would be to have our own retreat facility ... a place where we could host as many events as we needed to, where our attendees could enjoy the privacy of their own rooms and feel comfortable and at home from the moment they walked in the door.Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way.  I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

That first bereaved-parent retreat in April of 2011 turned out to be above and beyond all we could have ever asked or imagined.  We knew from our experience at the Respite Retreat what God could do when a group of like-minded bereaved parents got together ... but this first While We're Waiting Weekend was such a sweet confirmation of what we believed God was calling us to do.Buoyed by the success of this first event, we quickly scheduled our next retreat for November of 2011.  And you know what?  That retreat almost didn't "make." Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way.  I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

Over the next few months, we met frequently to discuss plans and pray about our upcoming retreat for bereaved parents.  Several times we drove out to Family Farm and included Stan and Donna May in our planning meetings.Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way. I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

Brad and I returned home from the Respite Retreat still basking in the glow of the new relationships we'd formed, the things we'd learned from spending time with other bereaved parents, and a renewed hope that it was still possible to have joy in life in spite of our great loss. We had a strong sense that God was calling us into a similar type ministry for those who had lost children, but we had no idea how to move forward with it.  We talked about it a lot, and we sought God's direction, but we just didn't have any kind of catalyst to push us forward. Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way. I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

Even though I didn't really want to go, and this thing was way outside my comfort zone, Brad and I signed up for the Respite Retreat scheduled for Labor Day Weekend in September of 2010.  We couldn't have known at the time what a profound impact it would have on our lives.  Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way. I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

During the final days of Hannah's life, many people dropped by the hospice center and left books, gifts, food, and other items for our family.  These kindnesses were so greatly appreciated.Most of these gifts were accompanied by a card indicating who had given them.  But one gift, a book called "Holding On To Hope" by Nancy Guthrie, was accompanied by a card signed only with the initials "plc".  The anonymous person who brought that gift could not have foreseen what an impact it would have in our lives. Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way.  I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org

Thank you for joining me for another bonus episode in this series in which I've been sharing our family's experiences in the last year of our daughter Hannah's life, which spanned from February 2008 through February 2009.  This series would not be complete without a discussion of the ministry which developed out of Hannah's homegoing.  If you'll indulge me for a few more bonus episodes, I'd like to share how God used Hannah's storm to birth the While We're Waiting ministry to bereaved parents.  As always, my desire is to give glory to God and point listeners to hope in Jesus along the way.  I would love to hear your thoughts on the show. Click here to send me a message!** IMPORTANT** - All views expressed by guests on this podcast are theirs alone, and may not represent the Statement of Faith and Statement of Beliefs of the While We're Waiting ministry. We'd love for you to connect with us here at While We're Waiting! Click HERE to visit our website and learn about our free While We're Waiting Weekends for bereaved parentsClick HERE to learn more about our network of While We're Waiting support groups all across the country. Click HERE to subscribe to our YouTube channelClick HERE to follow our public Facebook pageClick HERE to follow us on Instagram Click HERE to follow us on Twitter Click HERE to make a tax-deductible donation to the While We're Waiting ministryContact Jill by email at: jill@whilewerewaiting.org