Podcasts about seasonal influenza

In this special episode of Diabetes Core Update, our host, Dr. Neil Skolnik, discusses with two expert guests the recommendations for respiratory vaccinations in people with diabetes, the rise in vaccine hesitancy and some of the possible reasons for this hesitancy, and several ways to address vaccine hesitancy in the office. This special edition is sponsored by Sanofi.  Presented by: Neil Skolnik, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington–Jefferson Health John J. Russell, MD, Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Chair, Department of Family Medicine, Abington–Jefferson Health Aaron Sutton, LCSW, BCD, CAADC, Behavioral Health Faculty at the Family Medicine Residency Program at Abington–Jefferson Health; Chief Wellness Officer for Graduate Medical Education at Abington–Jefferson Health Select references mentioned in the podcast: Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2024–25 Influenza Season. MMWR Recomm Rep 2024;73:1–25. DOI: 10.15585/mmwr.rr7305a1 Recombinant or Standard-Dose Influenza Vaccine in Adults Under 65 Years of Age. N Engl J Med 2023;389:2245–2255. DOI: 10.1056/NEJMoa2302099 Influenza Vaccine as a Coronary Intervention for Prevention of Myocardial Infarction. Heart 2016;102:1953–1956. DOI: 10.1136/heartjnl-2016-309983

In this podcast, Dr. Valentin Fuster discusses a study on the significant impact of seasonal influenza on mortality and hospitalizations among patients with heart failure. The research highlights that influenza is responsible for substantial excess deaths and hospitalizations in this vulnerable group, emphasizing the need for better vaccination uptake and preventive measures to reduce these risks.

Michelle Fiscus, MD, FAAP from the Association of Immunization Managers (AIM) joins host Chris Stallman, CGC to discuss respiratory virus season and what pregnant people can do to help protect their babies against RSV, COVID-19, Seasonal Influenza (flu) and whooping cough (pertussis).   Resources mentioned in this episode: Association of Immunization Managers: Immunizationmanagers.org BOOSTRIX Tdap Vaccine - MotherToBaby Pregnancy Study

The current H5N1 avian flu outbreak in poultry and dairy cows in the US has raised the alarm on bird flu and its transmission risk across species. At present, the virus has infected 100 million birds across 48 states and 196 dairy herds across 14 states. Luckily, the H5N1 avian flu, which is very lethal in birds, does not transmit easily into humans nor does it generally cause severe and systemic symptoms when humans are infected. Still, workers most exposed to these infected animals are testing positive with 14 human cases reported so far since 2022. In this Communicable episode, hosts Angela and Nav are joined by avian flu expert Ron Fouchier (Erasmus MC Rotterdam, Netherlands) to discuss the most recent developments of the outbreak in the US and the potential risks H5N1 virus poses to humans. Understanding of the virus from its first reported outbreak in Hong Kong in 1997 to its global prevalence today is reviewed. While H5N1 bird flu does not pose as a global human health concern at present, unchecked practices in the dairy, meat, and agricultural industry sectors, in which workers are exposed to the virus, threaten to change the status quo. Learn why the threat is even more paramount in fall when human influenza or seasonal flu is widespread, and to what extent the government should also be involved in prevention and containment measures before it becomes, in Ron's words, another “missed opportunity.”          This episode was edited by Kathryn Hostettler and peer-reviewed by Dr. Simon Galmiche of the Institut Pasteur, Université Paris Cité, Paris, France.LiteratureUS Centers for Disease Control and Prevention (CDC). H5 Bird Flu: Current Situation. 2024. https://www.cdc.gov/bird-flu/situation-summary 

This podcast is published open access in Infectious Diseases and Therapy and is fully citeable. You can access the original published podcast article through the Infectious Diseases and Therapy website and by using this link: https://link.springer.com/article/10.1007/s40121-024-00932-3. All conflicts of interest can be found online. This podcast is intended for medical professionals.  Open Access This podcast is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The material in this podcast is included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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"Seasonal Influenza" (Health Education) Nway Oo Naing.This item belongs to: audio/opensource_audio.This item has files of the following types: Archive BitTorrent, Item Tile, Metadata, PNG, Spectrogram, VBR MP3

I en nylig publisert studie har forskerne sammenlignet dødeligheten ved covid-19 og sesonginfluensa. Covid-19-infeksjon gir en kjent økt risiko for facialisparese – men gir også covid-19-vaksinasjon økt risiko? BCG-vaksinen er kjent for å gi såkalt «off target»-effekter, altså at den beskytter mot flere infeksjonssykdommer enn tuberkulose. Nå er det forsket på om den også kan beskytte mot covid-19. Under pandemien tok likestillingen mellom kjønnene innen forskning et stort steg tilbake, da bare 11 % av de mest aktive forskerne i det første pandemiåret var kvinner. Hvorfor var det slik? Og har du hørt om Rosalind Franklin, kvinnen som var helt instrumentell for oppdagelsen av DNA-ets heliksstruktur? Ikke det? Sjefredaktør Are Brean forteller blant annet også om ny forskning på prostatakreft hos transkvinner, på om det er bedre å operere eller ikke operere pasienter med isjias, og om den dødelige hetebølgen i Europa i fjor.Tilbakemeldinger kan sendes til stetoskopet@tidsskriftet.no.    Stetoskopet produseres av Synne Muggerud Sørensen, Are Brean og Julie Didriksen ved Tidsskrift for Den norske legeforening. Ansvarlig redaktør er Are Brean.    Jingle og lydteknikk: Håkon Braaten / Moderne media Coverillustrasjon: Stephen Lee Artikler nevnt:Risk of Death in Patients Hospitalized for COVID-19 vs Seasonal Influenza in Fall-Winter 2022-2023 Association of SARS-CoV-2 Vaccination or Infection With Bell Palsy: A Systematic Review and Meta-analysis Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers Assessing COVID-19 pandemic policies and behaviours and their economic and educational trade-offs across US states from Jan 1, 2020, to July 31, 2022: an observational analysis Seven days in medicine: 19-25 April 2023 The State of the World's Children 2023 How pandemic publishing struck a blow to the visibility of women's expertise How Rosalind Franklin was let down by DNA's dysfunctional team Prostate Cancer in Transgender Women in the Veterans Affairs Health System, 2000-2022 Prenatal Exposure to Antiseizure Medication and Incidence of Childhood- and Adolescence-Onset Psychiatric Disorders Surgical versus non-surgical treatment for sciatica: systematic review and meta-analysis of randomised controlled trials Early surgery for sciatica Europe's record heatwave in 2022 caused many health harms, report finds

Episode 27 - December 2022 Topic: Flu Vaccination: Navigating Clinical Guidance and Addressing Hesitancy Host: James Millward, DMSc, PA-C Guests: Felicia Gutierrez, PA-C; Sarah McQueen, DMS, PA-C; Justin Wolfe MHS, PA-C Resources: AAPA/PA Foundation animated video - "Flu Vaccine: The More You Know" "In the Words of PAs" blog post - "Flu Vaccination: Using the Health Belief Model to Increase Vaccine Uptake" JAAPA: October 2022 - "Using the Health Belief Model to improve influenza vaccination rates" CDC - Influenza (Flu) CDC - Key Facts About Influenza (Flu) CDC - Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2022–23 Influenza Season CDC - Adjuvanted Flu Vaccine AAPA/PA Foundation animated video - "Flu Vaccine: The More You Know" Sanofi - Flu Shot Importance Flash Card Sanofi - Myth Busters Flash Card

Many people get sick with influenza in winter time, especially the elderly and children. It is recommended that people get their influenza vaccines, but many people are hesitant about the vaccination. We speak to Dr Ali Ziabari from Melbourne about the subject. - Di demsala zivistanê de gelek kes bi nixweşiya girîpê dikevin bi taybetî yên temen mezin û zarok ku di heman demê de derziya vaksînlêdanê heye. Lê gelek kes derbarê vakisînkirinê dudilin. Em derbarê vê mijarê bi Dr Elî Zêbarî re ji Melbourne diaxifîn.

Sam Lee, interim Co-CEO and President, and Jim Martin, interim Co-CEO and CFO of Cocrystal Pharma. They're a clinical stage biotech company using their proprietary drug development platform to create novel antiviral therapeutics to treat seasonal influenza and pandemic viral infections like COVID-19. Jim explains, "There are vaccines, and then there are therapeutics. We are a therapeutic company. We don't produce vaccines. Vaccines are more preventative. What we do is, once you get the illness, we stop the illness through our compounds. So as a therapeutic, you do need that one-two punch of both vaccines and therapeutics. And in the case of influenza, we have every year people getting vaccines, which are good. But the therapeutics that are necessary are far and few between." Sam elaborates, "So our compounds, the compound IDs of CC-42344, we're currently doing phase one study in Australia, this compound has an outstanding drug-resistant profile. We have not been able to isolate the drug-resistance strains from in vitro test-tube experiments. So we believe this compound is really designed for the pandemic as well as a seasonal treatment, particularly targeting for influenza A infection. And also, because of the excellent drug resistance profile, we believe this would be a real breakthrough influenza treatment for pandemic as well as seasonal infection." @CocrystalPharma #Flu #Influenza #Pandemic #SeasonalFlu #COVID #Vaccines #COVIDTreatments #FluTreatments cocrystalpharma.com Download the transcript here

Sam Lee, interim Co-CEO and President, and Jim Martin, interim Co-CEO and CFO of Cocrystal Pharma. They're a clinical stage biotech company using their proprietary drug development platform to create novel antiviral therapeutics to treat seasonal influenza and pandemic viral infections like COVID-19. Jim explains, "There are vaccines, and then there are therapeutics. We are a therapeutic company. We don't produce vaccines. Vaccines are more preventative. What we do is, once you get the illness, we stop the illness through our compounds. So as a therapeutic, you do need that one-two punch of both vaccines and therapeutics. And in the case of influenza, we have every year people getting vaccines, which are good. But the therapeutics that are necessary are far and few between." Sam elaborates, "So our compounds, the compound IDs of CC-42344, we're currently doing phase one study in Australia, this compound has an outstanding drug-resistant profile. We have not been able to isolate the drug-resistance strains from in vitro test-tube experiments. So we believe this compound is really designed for the pandemic as well as a seasonal treatment, particularly targeting for influenza A infection. And also, because of the excellent drug resistance profile, we believe this would be a real breakthrough influenza treatment for pandemic as well as seasonal infection." @CocrystalPharma #Flu #Influenza #Pandemic #SeasonalFlu #COVID #Vaccines #COVIDTreatments #FluTreatments cocrystalpharma.com Listen to the podcast here

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Donald Middleton, MD Influenza causes considerable morbidity and mortality in children. In fact, the CDC estimates that from the 2010-2011 season to the 2019-2020 season, seasonal flu-related hospitalizations among children younger than 5 years old have ranged from 7,000 to as high as 26,000 every year.1 This is a sobering reminder of the pivotal role vaccination plays in preventing influenza disease, and now, recent safety and immunogenicity data has led to the expanded age indication for the cell-based vaccine FLUCELVAX QUADRIVALENT. Explore that data and what this approval means for patients 6 months of age and older with Drs. Charles Turck and Donald Middleton. Centers for Disease Control and Prevention. Flu and young children. https://www.cdc.gov/flu/highrisk/children.htm. Accessed December 22, 2021 USA-QIVc-21-0169 December 2021

Host: Charles Turck, PharmD, BCPS, BCCCP Guest: Mark Blatter, MD Despite their crucial role in preventing seasonal influenza, traditional influenza vaccines may not be providing as much protection as we thought, leading researchers to take a look at different methods of vaccine production, specifically cell-based flu vaccine production. Here with Dr. Charles Turck to discuss influenza prevention and the latest evidence supporting a cell-based vaccine option is Dr. Mark Blatter. USA-QIVc-21-0146 November 2021

To meet the growing needs of the Long-Term Care community, NETEC has developed a Personal Protective Equipment educational resource for Long-Term Care Facilities. Targeted toward all professionals in Long-Term Care, from administration to frontline workers, this resource will allow facilities to learn or refresh their knowledge on critical concepts of PPE management and use. Join NETEC host Jill Morgan, RN, Emory Healthcare, and special guest, Carly Snider, LPN, of House of Hope Alzheimer's Care, in Omaha, Nebraska, as they discuss the timeliness and importance of this PPE resource and its impact on the LTC communities Carly represents.Questions or comments for NETEC? Contact us: info@netec.orgFind us on the web: netec.orgGuestCarly Snider, LPN, House of Hope Alzheimer's CareCarly is the Community Nurse at House of Hope Alzheimer's Care in Omaha, Nebraska. There she directs and oversees daily operations encompassing resident care, health, and well-being, as well as care staff management, training, education, and scheduling.HostJill Morgan, RNJill Morgan is an RN and subject matter expert in PPE for NETEC. Member APIC, ASTM, AAMI. For 35 years Jill has been an emergency department and critical care nurse, and now splits her time between education for NETEC and clinical research, most of it centering around Infection Prevention and Personal Protective Equipment.ResourcesNETEC: Long-Term Care: Personal Protective Equipment (PPE) Education: https://repository.netecweb.org/exhibits/show/ncov/item/1617Evaluating the national PPE guidance for NHS healthcare workers during the COVID-19 pandemic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354042/Personal protective equipment (PPE) and infection among healthcare workers – What is the evidence?: https://onlinelibrary.wiley.com/doi/full/10.1111/ijcp.13617?casa_token=f6BkRzYA1YAAAAAA%3AQxATzu-MQdGzNUGacsnFE_RqcEFJ19UodAIYlrpfU_WlXJJDxWIu9S8P6CLV-qSV5mhhkjvX2RNonABurden of Occupationally Acquired Pulmonary Tuberculosis among Healthcare Workers in the USA: A Risk Analysis: https://academic.oup.com/annweh/article/61/2/141/2765104Health Care–Acquired Viral Respiratory Diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170875/(PDF) Prevention and Control of Outbreaks of Seasonal Influenza in Long-Term Care Facilities: A Review of the Evidence and Best Practice Guidance: https://www.euro.who.int/__data/assets/pdf_file/0015/330225/LTCF-best-practice-guidance.pdfRespiratory viruses on personal protective equipment and bodies of healthcare workers:

Dr. Jonathan Edelman, MD, Vice President, Clinical Development at Seqirus discusses the Phase 3 clinical data presented at the 2021 Pediatric Academic Societies (PAS) virtual conference that supports the use of cell-based quadrivalent influenza vaccine (QIVc) in children 6 months to

Host: Jennifer Caudle, DO Guest: Lauren Angelo, PharmD, MBA Egg-based manufacturing methods for influenza vaccines have been a mainstay of production. But the recent emergence of a cell based manufacturing method changes our approach entirely. What will this paradigm shift look like? Are there new opportunities and challenges to address along the way? Here to answer that and other practical questions is Dr. Lauren Angelo, Associate Dean for Academic Affairs and an Associate Professor of Pharmacy Practice at Rosalind Franklin University of Medicine and Science College of Pharmacy. USA-CRP-21-0030 May 2021

Host: Jennifer Caudle, DO Guest: Archana Chatterjee, MD, PhD Since adults 65 years and older bear the greatest burden of severe disease from influenza, it’s critically important to ask ourselves the following question: what can we do to better prevent seasonal influenza infections in older adults? Here to answer that and other practical questions is Dr. Archana Chatterjee, MD, PhD, Dean of the Chicago Medical School and Vice President for Medical Affairs at Rosalind Franklin University in Chicago, IL. USA-CRP-21-0004 January 2021

Au Pharmascope, on constate que nos formations pour traiter l’influenza seront vraisemblablement peu utiles cette année, mais bon...vous pourrez les écouter à nouveau l’an prochain! Dans ce 68ème épisode, Nicolas, Sébastien et Isabelle discutent du traitement préventif de l’influenza et de tout ce que ça implique. Les objectifs pour cet épisode sont: Identifier les patients qui peuvent bénéficier d’un traitement préventif de l’influenzaExpliquer les bénéfices et les risques des traitements préventifs contre l’influenza Ressources pertinentes en lien avec l’épisode Études portant sur la prophylaxie de gens habitant au même domicileIkematsu H et coll. Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts. N Engl J Med. 2020;383:309-20. Kaiser L et coll. Short-term treatment with zanamivir to prevent influenza: results of a placebo-controlled study. Clin Infect Dis. 2000;30:587-9. Hayden FG et coll. Inhaled zanamivir for the prevention of influenza in families. Zanamivir Family Study Group. N Engl J Med. 2000;343:1282-9. Monto AS et coll. Zanamivir prophylaxis: an effective strategy for the prevention of influenza types A and B within households. J Infect Dis. 2002;186;1582-8. Welliver R et coll. Effectiveness of oseltamivir in preventing influenza in household contacts: a randomized controlled trial. JAMA. 2001;285:748-54. Études portant sur la prophylaxie en continu en saison grippaleHayden FG et coll. Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza. N Engl J Med. 1999;341:1336-43. Monto AS et coll. Zanamivir in the prevention of influenza among healthy adults: a randomized controlled trial. JAMA. 1999;282:31-5. LaForce C et coll. Efficacy and safety of inhaled zanamivir in the prevention of influenza in community-dwelling, high-risk adult and adolescent subjects: a 28-day, multicenter, randomized, double-blind, placebo-controlled trial. Clin Ther. 2007;29:1579-90. Études portant sur la prophylaxie dans les unités en éclosionBooy R et coll. Treating and preventing influenza in aged care facilities: a cluster randomised controlled trial. PLoS One. 2012;7:e46509. Gravenstein S et coll. Inhaled zanamivir versus rimantadine for the control of influenza in a highly vaccinated long-term care population. J Am Med Dir Assoc. 2005;6:359-66. Lepen L et coll. Five-Day vs 10-Day Postexposure Chemoprophylaxis With Oseltamivir to Prevent Hospital Transmission of Influenza: A Noninferiority Randomized Open-Label Study. Open Forum Infect Dis. 2020;7:ofaa240. Guide de l’INESSSInstitut national d’excellence en santé et en services sociaux. Guide d’usage optimal -  Traitement et prophylaxie de l’influenza chez l’enfant et l’adulte dans le contexte de la covid-19. Décembre 2020. Lignes directrices de l’IDSAUyeki TM et coll. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis. 2019;68:e1-47. Lignes directrices canadiennesAoki FY et coll. Use of antiviral drugs for seasonal influenza: Foundation document for practitioners - Update 2019. JAMMI. 2019;4:60-82. Rapports d’activité grippale au Canada (ÉpiGrippe)Gouvernement du Canada. Grippe (influenza): Surveillance ÉpiGrippe. 2020. Tableau comparatif des symptômes de l’influenza, de la COVID-19 et du rhumeAlberta Health Services. Disponible en ligne.

Au Pharmascope, on est de plus en plus confiant que l’influenza ne se pointera pas le bout du nez cette année, mais on ne prend aucune chance! Dans ce 67ème épisode, Nicolas, Sébastien et Isabelle discutent du traitement de l’influenza. Les objectifs pour cet épisode sont: Décrire les objectifs de traitement de l’influenzaIdentifier les patients qui peuvent bénéficier d’un traitement de l’influenzaExpliquer les bénéfices et les risques des traitements antiviraux contre l’influenza Ressources pertinentes en lien avec l’épisode Revue systématique et méta-analyse portant sur les traitements antivirauxJefferson T et coll. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev. 2014;2014:CD008965. Étude portant sur l’oseltamivirButler CC et coll. Oseltamivir plus usual care versus usual care for influenza-like illness in primary care: an open-label, pragmatic, randomised controlled trial. Lancet. 2020;395:42-52. Études CAPSTONE-1 et 2 portant sur le baloxavirHayden FG et coll. Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018;379:913-23. Ison MG et coll. Early treatment with baloxavir marboxil in high-risk adolescent and adult outpatients with uncomplicated influenza (CAPSTONE-2): a randomised, placebo-controlled, phase 3 trial. Lancet Infect Dis. 2020; 20:1204-14. Guide de l’INESSSInstitut national d’excellence en santé et en services sociaux. Guide d’usage optimal -  Traitement et prophylaxie de l’influenza chez l’enfant et l’adulte dans le contexte de la covid-19. Décembre 2020. Lignes directrices de l’IDSAUyeki TM et coll. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis. 2019;68:e1-47. Lignes directrices canadiennesAoki FY et coll. Use of antiviral drugs for seasonal influenza: Foundation document for practitioners - Update 2019. JAMMI. 2019;4:60-82. Rapports d’activité grippale au Canada (ÉpiGrippe)Gouvernement du Canada. Grippe (influenza): Surveillance ÉpiGrippe. 2020. Tableau comparatif des symptômes de l’influenza, de la COVID-19 et du rhumeAlberta Health Services. Disponible en ligne.

A cohort study done to comparatively examine differences in risk of clinical manifestations and death among people admitted to hospital with coronavirus disease 2019 (COVID-19) and seasonal influenza.

Au Pharmascope, on ne sait pas encore si l’influenza se pointera le bout du nez cette année, mais on ne prend aucune chance! Dans ce 65ème épisode, Nicolas, Sébastien et Isabelle discutent de l’épidémiologie, de la transmission, de la présentation clinique et du diagnostic de l’influenza. Les objectifs pour cet épisode sont: Décrire les méthodes de transmission de l’influenzaDistinguer la présentation clinique de l’influenza de celle de la COVID-19 et du rhumeÉvaluer le patient présentant un syndrome d’allure grippale Ressources pertinentes en lien avec l’épisode Guide de l’INESSSInstitut national d’excellence en santé et en services sociaux. Guide d’usage optimal -  Traitement et prophylaxie de l’influenza chez l’enfant et l’adulte dans le contexte de la covid-19. Décembre 2020. Lignes directrices de l’IDSAUyeki TM et coll. Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis. 2019;68:e1-47. Lignes directrices canadiennesAoki FY et coll. Use of antiviral drugs for seasonal influenza: Foundation document for practitioners - Update 2019. JAMMI. 2019;4:60-82. Rapports d’activité grippale au Canada (ÉpiGrippe)Gouvernement du Canada. Grippe (influenza): Surveillance ÉpiGrippe. 2020. Tableau comparatif des symptômes de l’influenza, de la COVID-19 et du rhumeAlberta Health Services

Episode 33: The Flu. Saba and Dr Arreaza gave us a brief review on the flu shot. Influenza vaccination starts at 6 months of age. Vaccinate everyone including pregnant women. Pectoriloquy is basically being able to understand the voice of a patient with a stethoscope placed on their chest. We learned the Spanish word gripe (gree-pay) which means cold and flu in Spanish. The sun rises over the San Joaquin Valley, California, today in October 30, 2020.Halloween is just around the corner! Today we will talk about vaccines because the new influenza season just started. If you have not realized it yet, this podcast is a strong defender of vaccines. So today we bring you what you need to know about the feared flu shot.Some fun facts about cold and flu symptoms. A cough can travel as fast as 50 mph and expel almost 3,000 droplets in just one go. Sneezes can travel up to 100 mph and create about 100,000 droplets. Yikes![1] During a pandemic, coughing or sneezing in public may even be more embarrassing than farting. Did you know that the average adult produces about 1.5 quarts of mucus a day, that’s 48 ounces! and we swallow most of it. As a reference, a Big Gulp has about 30 ounces. The amount of mucus can double or triple during infections. That’s a lot to swallow!This is Rio Bravo qWeek, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program, from Bakersfield, California. Sponsored by Clinica Sierra Vista, Providing compassionate and affordable care since 1971. “If you are neutral in situations of injustice, you have chosen the side of the oppressor. If an elephant has its foot on the tail of a mouse and you say that you are neutral, the mouse will not appreciate your neutrality.” — Desmond Tutu.This is not a podcast about politics, but with elections coming soon, we remind everyone to vote for the candidate who represents their values and beliefs. The two big contenders, Donald Trump and Joe Biden, have their own opinions and two different visions of what they want to do in the following 4 years in America. So, go and vote! You can decide who is the oppressor and who is the oppressed, based on your own judgement.Here we have Saba Ali, a fourth-year medical student who will talk about influenza vaccine.Timing of vaccineSaba: Remember to start influenza vaccination at 6 months of age. Any patient who has not received any influenza vaccine before age 8 should receive 2 doses 1 month apart. Vaccination is most effective if received by the end of October, although a vaccine administered in December or later is likely still beneficial. Intranasal vaccineArreaza: And for those who are scared of needles, we have good news: The “intranasal vaccine” or live attenuated influenza vaccine (LAIV4) is approved for use in healthy non-pregnant individuals, 2 years through 49 years of age. Saba: Don’t use LAIV4 in younger than 2 years or older than 50 years, pregnant women, patients with severe allergies to previous flu vaccines, patients younger than 18 receiving aspirin or salicylate-containing medications, immunosuppressed patients, caregiver of immunosuppressed patients, children younger than 5-year-old with asthma, people on antiviral medications, patients with active communication between the CSF and oropharynx, nasal pharynx, nose, or ear, or any other cranial CSF leak, and patients with cochlear implants, asplenia or persistent complement component deficiencies.Types of vaccinesArreaza: CDC recommends using any age-appropriate influenza vaccine: 1. inactivated influenza vaccine [IIV], 2.  recombinant influenza vaccine [RIV], or 3. live attenuated influenza vaccine (LAIV). No preference is expressed for any influenza vaccine over another. Egg AllergySaba: A common question we have from patients is “I have egg allergy; can I still get the flu shot?”Arreaza: The answer is: The influenza vaccine contains potential allergic components that may cause an anaphylactic reaction. One such allergen is egg proteins. Currently, all vaccines except for (Flublok (RIV4) quadrivalent for ≥18yo, and Flucelvax (IIV4) quadrivalent for ≥4yo) may contain trace amounts of egg proteins such as ovalbumin. Healthcare providers should be aware that allergic reactions, although rare, can occur at any time, even in the absence of a history of previous allergic reactions to vaccines. Therefore, providers giving the vaccination should have a plan for emergencies and be trained in cardiopulmonary resuscitation. Saba: The following are recommendations for patients with a history of egg allergies:Patients with only urticaria after exposure to egg should receive an influenza vaccine appropriate for their age and health status. Patients that report having more severe reactions to egg and required epinephrine or other emergency intervention can also get any vaccine appropriate for age and health status. If a vaccine other than CCIIV4 or RIV4 is given, it should be given in an inpatient or outpatient setting supervision of a healthcare provider who can manage and identify severe allergic reactions. No post-vaccination observation is recommended; however, providers are advised to observe patients for 15 minutes after administering the vaccine for concern of injury secondary to syncope. ContraindicationsArreaza: When is the flu shot contraindicated? The only true contraindication to the influenza vaccine is a severe allergic reaction to a previous influenza vaccination regardless of the suspected allergen responsible for the reaction. Gillian-Barre SyndromeSaba: Let’s talk briefly about Guillain-Barre Syndrome (GBS). GBS is a rare autoimmune disorder which causes muscle weakness and paralysis. GBS can last a few weeks or longer. Most people recover fully, but some people have long-term nerve damage. GBS can be deadly if the respiratory muscles are affected. In the United States, an estimated 3,000 to 6,000 people develop GBS each year, about 80 to 160 cases each week, regardless of vaccination. Arreaza: Since 1973, the data about increased risk associated with influenza vaccines is variable and inconsistent across flu seasons. When there has been an increased risk, it has consistently been in the range of 1-2 additional GBS cases per million flu vaccine doses administered.Saba: Anyone can develop GBS; however, it is more common among older adults. The incidence of GBS increases with age, and people older than 50 years are at greatest risk for developing GBS. What if the patient has history of GBS? Should they get vaccinated? Arreaza: A history of GBS within 6 weeks of a previous dose of any type of influenza vaccine is considered a precaution to vaccination. Persons who are not at higher risk for severe influenza complications and who are known to have experienced GBS within 6 weeks of a previous influenza vaccination generally should not be vaccinated. As an alternative to vaccination, providers might consider using influenza antiviral chemoprophylaxis for these persons. Influenza and COVID-19Saba: And what about COVID-19 patients? Visits for routine vaccination should be deferred for asymptomatic and pre-symptomatic persons who have tested positive for SARS-CoV-2, the virus that causes Influenza vaccine should be postpone in patient with asymptomatic COVID-19 for 10 days from their positive test result. Arreaza: For symptomatic persons with suspected or confirmed COVID-19, visits for routine vaccination should be deferred until criteria have been met for them to discontinue isolation: at least 10 days after symptom onset AND 24 hours with no fever without the use of fever-reducing medications AND COVID-19 symptoms are improving, AND the person is no longer moderately to severely ill. Moderate to severe illness with or without fever is a precaution to vaccination for all vaccines. Saba: If a patient has been exposed to a person with COVID-19, wait until their 14-day quarantine period has ended. For additional considerations regarding influenza vaccination of persons who are already in healthcare or congregate settings, we invite you to review the most current information from the CDC and ACIP websites.____________________________Speaking Medical: Pectoriloquyby Levi Shen, MS3The word for today is pectoriloquy.Normally, you should not be able to understand the words “One-two-three” when you auscultate the lungs. Pectoriloquy refers to the increased resonance of the voice through lung structures so that it is intelligible during auscultation. It is a useful tool that clinicians may employ to identify areas of consolidation in a patient’s lung, which may indicate pneumonia, fibrosis or even cancer. Types of pectoriloquy include: Egophony: It is a result of enhanced transmission of high-frequency sound across fluid or solid, with lower frequencies filtered out. In practice, this would involve a patient making a long E sound which is then heard as an A sound by the physician; this is known as the E to A transition.Bronchophony: Normally, the sound of a patient's voice is less clear in peripheral airways as compared to the larger airways. In bronchophony however, the patient's voice remains loud at the periphery, indicating possible consolidation. Whispered pectoriloquy: It is similar to bronchophony, except that in this test, the patient is told to whisper. If there is consolidation, the physician should be able to hear the patient clearly during auscultation. Bronchophony and whispered pectoriloquy take advantage of the fact that sound travels faster through fluid and solid, resulting in decreased loss of volume. Common words that physicians ask patients to repeat are “one-two-three”, "toy boat”, "Scooby Doo", and “blue balloons”. Another common word used is “ninety-nine.” There is historical significance to this. When the test was originally described by a German physician, he used the phrase "neunundneunzig”, which he found would cause maximum vibration of the chest. And what does that word mean in English? Ninety-nine.When physicians find pectoriloquy during physical, they may confirm diagnosis with labs and imaging.Remember the word of this week, pectoriloquy.____________________________Espanish Por Favor: Gripeby Anabell Lorenzo, MD“Doctora, tengo gripe”. The Spanish word of the week is gripe. When you see the spelling of the Spanish word gripe, in English you may think the patient has a colic. That’s why you can find “gripe water” which is a non-prescription medication for colicky in babies. But gripe (gree-pay) means having a cold or the flu. People may use the word gripe for any runny nose, cough, sneezing… or any upper respiratory symptoms. Your job is to determine what is causing the gripe based on your clinical judgment, and use additional studies as needed. Most gripes are viral colds, and most of them need only conservative management (rest, fluids, acetaminophen), but don’t forget to rule out other serious causes, including COVID-19 and influenza. During this flu season, remember the Spanish word gripe.____________________________For your Sanity: Skeletonsby Tana Parker, MD, and Steven Saito, MDWhere do you send a patient injured in a Peek-a-Boo accident? Straight to the I.C.U.Why don’t skeletons ever go trick-or-treat? Because they have no body to go with.Why didn’t the skeleton cross the road? Because it did not have the guts to do it.Within minutes the detectives knew what the murder weapon was. It was a brief case. Conclusion: Now we conclude our episode number 33: “Flu”. Saba and Dr Arreaza gave us a brief review on the flu shot. Remember to start influenza vaccination at 6 months of age, and vaccinate everyone including pregnant women. Then we learned the word pectoriloquy, which is basically being able to understand the voice of a patient with a stethoscope placed on the chest. And to finish up our episode, we learned the Spanish word gripe (gree-pay) which means cold and flu. Thanks for listening to Rio Bravo qWeek. If you have any feedback about this podcast, contact us by email RBresidency@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. This podcast was created with educational purposes only. Visit your primary care physician for additional medical advice. This week we thank Hector Arreaza, Saba Ali, Anabell Lorenzo, and Levi Shen. Audio edition: Suraj Amrutia. See you next week! _____________________References:“How Fast Is a Sneeze Versus a Cough? Cover Your Mouth Either Way!”, May 12, 2016, American Lung Association, https://www.lung.org/blog/sneeze-versus-cough#:~:text=Sneezes%20win%20though%E2%80%94they%20can,create%20upwards%20of%20100%2C000%20droplets, accessed on October 29, 2020.  “Mucus is gross. But here are 9 things you should know about it.”, VOX, https://www.vox.com/2015/2/11/8013065/mucus-snot-boogers, accessed on October 29, 2020.  Grohskopf LA, Alyanak E, Broder KR, et al. Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices — United States, 2020–21 Influenza Season. MMWR Recom Rep 2020;69(No. RR-8):1–24. DOI: http://dx.doi.org/10.15585/mmwr.rr6908a1 Influenza Vaccination: Updated 2020–2021 Recommendations from ACIP, Am Fam Physician. 2020 Oct 15;102(8):505-507. https://www.aafp.org/afp/2020/1015/p505.html 

Bill Spadea of New Jersey 101.5 reads from an article by a Swedish doctor about coronavirus stats.

This week's Addicted to Fitness debates whether the media coverage of the most recent viral outbreak is warranted. Nick and Shannon compare statistics of the coronavirus and seasonal influenzas to determine which virus Americans should be more concerned with. Give it a listen and let us know what you think by leaving a rating & review in Apple Podcasts.  Check out addictedtofitnesspodcast.com for additional information on the topics discussed in this week's episode. Like & Follow the Addicted to Fitness Podcast Facebook page (Facebook.com/addictedtofitnesspodcast). Make sure to check out our Shop page on addictedtofitnesspodcast.com to view ATF approved products from The Hemp & Coffee Exchange, Stick Mobility, and Gainful Protein (gainful.com/addicted). 

Dr. Gregg Sylvester, Vice President of Medical Affairs at Seqirus discusses their portfolio of influenza vaccines with the majority of doses coming from its adjuvanted and cell-based technology platforms. There is a range of options for children aged six months and older and the first-and-only adjuvanted seasonal influenza vaccine developed for people aged 65 and older.

Overview: FAQ for Seasonal Influenza: When, Who, and How to Manage? (Not for CME)   Guest: Robert H. Hopkins, Jr, MD, MACP, FAAP &  Charles Vega, MD, FAAFP

The Infectious Diseases Society of America'sGuideline Update: Concise summaries of the most important IDSA guidelines. This episode discusses the 2018 Update of the Clinical Practice Guidelines on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. For the full version of the guidelines presented, please go to www.idsociety.org or see the full article in Clinical Infectious Diseases 2018. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Associate Director, Family Medicine Residency Program, Abington Jefferson Health Andrew T. Pavia, M.D. The George and Esther Gross Presidential Professor at the University of Utah, Chief of the Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City.

En el episodio final de esta miniserie de virus respiratorios asociados a la temporada invernal, hablamos de los virus de influenza.    Referencias: Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenza. Clin Infect Dis . Dec 19, 2018. Florian Kramer y colaboradores. Influenza. Nature Review Disease Primer. ID: (2018) 4:3   Frase de la Semana:  Esta semana los dejo no con una, pero con dos frases breves de Honore de Balzac. Escritor francés y una de las grandes figuras fundamentales del realismo europeo, a menudo considerado como el fundador de la novela moderna y uno de los principales representantes de la novela realista francesa.  La primera dice: “Existen en nosotros varias memorias. El cuerpo y el espíritu tienen cada una la suya” la segunda:  “El amor no es solo un sentimiento. Es también un arte”    

Ya nos adentramos en la temporada de influenza del 2018-2019 en el hemisferio norte y estamos empezando a ver casos aislados de la enfermedad. Así que el programa de esta semana hablamos de influenza y sobre todo de la vacuna contra esta infección viral.  Referencia: Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices—United States, 2018–19 Influenza Season. James G. Donahue y colaboradores. Association of spontaneous abortion with receipt of inactivated influenza vaccine containing H1N1pdm09 in 2010–11 and 2011–12. Vaccine, Sep 25, 2017.   Frase de la Semana: La tomamos de la escritora chilena Isabel Allende.  Nacida en Lima Perú el 2 de agosto de 1942. Está considerada la más popular novelista iberoamericana actual habiendo vendido más de 51 millones de ejemplares y su trabajo ha sido traducido a más de 27 idiomas. Entre sus libros más celebrados encontramos “El plan infinito”, “La casa de los espíritus” y “Eva Luna”. La frase la encontramos en su libro “La suma de los días” y dice: “Memoria selectiva para recordar lo bueno, prudencia lógica para no arruinar el presente, y optimismo desafiante para encarar el futuro”  

Author: Sam Killian, MD Educational Pearls:   Japan recently approved baloxavir marboxil (Xofluza), which may potentially "kill" Flu A/B within 24 hours Recent RCT trial showed superiority over oseltamavir (Tamiflu) in cessation of viral shedding (24 vs 72 hours) Compared to placebo, superior in time to symptom resolution (53.7 vs 80.7  hours) Administered as single dose Yet to be considered for FDA approval   References Portsmouth S, Kawaguchi K, Arai M, Tsuchiya K, Uehara T. Cap-dependent Endonuclease Inhibitor S-033188 for the Treatment of Influenza: Results from a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study in Otherwise Healthy Adolescents and Adults with Seasonal Influenza. Open Forum Infectious Diseases. 2017;4(Suppl 1):S734. doi:10.1093/ofid/ofx180.001.  

This podcast discusses the recently released research report, Seasonal Influenza in the United States 2016‐2017.

Reading by Arthur Caplan, PhD, author of Managing the Human Toll Caused by Seasonal Influenza

Margaret Parker, MD, FCCM, speaks with Carl O. Eriksson, MD, MPH, lead author on an article published in the November Pediatric Critical Care Medicine

Margaret Parker, MD, FCCM, speaks with Carl O. Eriksson, MD, MPH, lead author on an article published in the November Pediatric Critical Care Medicine

Guest: Norman Edelman, MD Host: Matt Birnholz, MD Host: Michael Greenberg, MD We are moving closer to the height of what many feel will be an extraordinarily busy flu season, with H1N1 and the seasonal flu both central parts of the discussion. We don't know exactly how serious H1N1 will be, but we do know that it's here, that many more people could get sick, and that we have to be prepared to deal with it. Hosts Dr. Michael Greenberg and Dr. Matt Birnholz speak with Dr. Norman Edelman, chief medical officer for the American Lung Association and a professor of preventive medicine and internal medicine at the State University of New York at Stony Brook. Dr. Birnholz and Dr. Greenberg will also give you their take on an amusing recitation of the health reform bill in the House known as HR 3200. They will also play back the winning entry in an entertaining yet informative contest to create a public service announcement on H1N1, co-sponsored by the U.S. Department of Health and Human Services. You won't want to miss it!