Podcasts about ubx

This week, we were all over the place with a bunch of different designs and experiments. After last week's analysis of the TLV320DAC3100, we made some updates to the design and re-booked prototype PCBs. We also designed a triple-matrix bonnet: with our latest work on getting HUB75 RGB matrices working on the Raspberry Pi 5, we can now do matrix control on the latest Pi 5 chip. But we're limited by the RP1 chip, so to get big displays going, we'll need multiple strands—these don't use significantly more bandwidth because half of the pins are shared. Finally, we ended the week by getting another older prototype working: the SAM-M8Q is an entry-level all-in-one GPS from u-blox. It comes with both UART and I2C interfaces, plus a built-in antenna, so it's ready to go out of the box. The NMEA interface is trivial, but we also wanted to try out the UBX interface, and thankfully, Claude 3.7 was able to vibe-code it for us in a jiffy.

Heeeey, we're just having a super chill vibe here at the desk of Ladyada—writing a driver for the uBlox M8Q https://blog.adafruit.com/2024/09/10/a-mini-gps-from-ublox-with-i2c-and-uart/ which has both I2C and UART interfaces. As expected, it can do everyday NMEA output, but it can also do UBX, a "compressed" protocol for advanced data reads and writes over I2C/UART—or even SPI on some other chips. However, the UBX protocol is a hugely complex driver to implement, with dozens of commands and hundreds of flags. But why stress when you can viiiibe? We're using this beast of a spec as an excuse to try out the new Claude 3.7, which is doing great at chomping through the UBX documentation roughage and giving us some nice code on the other side. Within an hour, we're able to connect and switch to UBX mode by sending a well-formed message and receiving an ACK. What we like about coding with a good LLM is that it does the work we sometimes get lazy over, like handling various error conditions, timeouts, and verbose error messages. Visit the Adafruit shop online - http://www.adafruit.com ----------------------------------------- LIVE CHAT IS HERE! http://adafru.it/discord Subscribe to Adafruit on YouTube: http://adafru.it/subscribe New tutorials on the Adafruit Learning System: http://learn.adafruit.com/ ----------------------------------------- #ai #gps #coding

You've heard me speak about her on the pod before…  Today I'm sitting down with Liv, the owner of the FASTEST growing UBX in New Zealand. From running three studios, leaving home at 3 am to drive to her third studio (without taking away from her working hours), and feeling burnt out… Liv shares how she went from “winging it” to becoming a thriving multi-studio owner, who now brings in over $240k in additional profit annually. On today's episode, Liv is walking us through her game-changing strategies including how she hired the team member who completely turned her business around, and how she has staff thanking her for her leadership decisions. Tune in to find out: The steps Liv took to add 150+ members to her studio in 6 months! How Liv built a strong, aligned team that actually looks out for each other The change that stopped Liv from having to micromanage her team Strategies to managing multiple studios while maintaining balance in her work life and personal life Prefer watching to listening? Check out the video version of the podcast here. Check out Liv's studios on IG @ubxormiston @ubxmteden or at @oliviaashbys Liv's Studio Websites: www.ubxtraining.com/gym/Ormiston www.ubxtraining.com/gym/MountEden WANT MORE: To say thank you for listening to the pod we'd like to gift you a FREE session to brainstorm a 3 Step Action Plan for your gym or fitness studio so you know EXACTLY what step you need to take to grow. Book in yours here Find out more about working with Geronimo at thegeronimoacademy.com Want to follow along behind the scenes? Check out @thegeronimoacademy and @hey.doza

What new car in 2024 would you drive forever? Would it be the same car if you had no budget?   Hey if you have any suggestions or want some good and bad advice about what you should buy next. email us at thebscarguys@gmail.com   Anna backup: https://shop.ford.com/configure/bronco/config/paint/Config[%7CFord%7CBronco%7C2024%7C1%7C1.%7C...PS6...A6UAC.ABAAQ.C1XAC.2DR.FHIAE.77H.]   Anna Pick: https://www.jeep.com/bmo.wrangler.html#/build/interior/27205/CUJ202410JLJS72B/2TY/APA,PBJ,X9,ERC,DEM,DMF,Z1E,TXA,WFV,VL,SDD,UBX,XE5,CWA,LFR,MMU,23Y   Charger Build and Price a Charger | Dodge Charger for Sale Stelvio Q4 Build & Price a Alfa Romeo Stelvio Today! | Alfa Romeo USA Macan GTS Macan GTS | Porsche Car Configurator GT-R GT-R Configurator | Summary | Nissan USA CT-5 V Blackwing 2024 CT5 | Summary | Cadillac RS Q8 Summary > 2024 RS Q8 > 2024 > RS Q8 [REDIRECT] > Audi | Luxury sedans, SUVs, convertibles, electric vehicles & more (audiusa.com) X3M Build Your Own – View Build and Get a Quote – BMW USA Alpina B8 Build Your Own – View Build and Get a Quote – BMW USA   Bill backup: https://www.audiusa.com/us/web/en/models/a6/rs6-avant/2024/overview/summary.html   Bill Pick: https://configurator.porsche.com/en-US/model/992880?options=04D.0I1.0NA.0P8.0TC.1BV.1G8.1LX.1MI.1N3.1NE.1P0.1X2.2C5.2D0.2V1.2W6.3FF.3HB.3J7.4GP.4L2.5KS.5MK.6BA.6E1.6F0.6FW.6NA.6Q2.6XA.7AL.7HB.7K3.7M3.7UG.8JU.8LH.8T1.8VH.9AD.9JA.9VL.9WT.APP.AYX.BHM.D2Q.F37.FM7.G0W.G9.KA2.KQ1.Q1K.QH1.QJ2.QQ0.QU4.ST.UI2.UP9.UX6.VC2.VR0.VW4.Z1S.ZGA&viz-environment=studio --- Send in a voice message: https://podcasters.spotify.com/pod/show/thebscarguys/message

OIS Podcast host Carey Powers caught up with four ophthalmology execs and one principal investigator to talk about some of the most exciting developments in retina R&D.Her guests include:Houman David Hemmati, MD, PhD, Cofounder and Chief Medical Officer of Optigo Biotherapeutics   Michael Tsipursky, MD, CEO and Cofounder of Revive BiotechMichael Singer, MD, Clinical Professor of Ophthalmology at University of Texas Health Science Center, Director of Clinical Research at Medical Center Ophthalmology Associates, and Principal Investigator for Unity Biotechnology's BEHOLD trialSamarendra Mohanty, PhD, President and Cofounder; and Sulagna Bhattacharya, CEO and Cofounder of Nanoscope TherapeuticsOptigo is developing binders intended to extend the duration of top-performing intravitreal drugs without compromising efficacy. The company has already had promising results in clinical trials with aflibercept. What's next?Revive Biotech focuses on central retinal artery occlusion. Its products work by injecting oxygen-loaded nanobubbles into the eye intravitreally. Preclinical studies have advanced through proof of concept. Nanobubbles?Dr. Singer is a principal investigator in Unity Biotechnology's clinical trial for UBX-1325, a therapeutic in development to treat diabetic macular edema and wet AMD. If approved, the product could work as an adjunct to anti-VEGF therapies.Nanoscope Therapeutics is developing gene therapies that focus on ambient light-sensitive molecules to treat inherited and acquired retinal diseases. Its lead product, MCO-010, is moving through Phase II trials. Why ambient light?Tune in to hear today's experts discuss:How Optigo plans to extend the duration of afliberceptThe impact of extending duration activity on patients, physicians, and payersWhat Optigo plans to accomplish over the next 12 monthsWhat's behind Revive Biotech's proprietary technology and what makes it unique.The milestones it has completed so far with relation to clinical trials, intellectual property, and fundingThe new class of therapeutics being developed by Unity BiotechnologyThe data released so far on the UBX-1325 BEHOLD trialIf approved, the impact of UBX-1325—an agent that may potentially extend the life of anti-VEGF therapies—on clinical practiceThe potential impact of Nanoscope Therapeutics's MCO-010 on patient communitiesThe feedback reported from clinical trial participantsThe critical milestones Nanoscope Therapeutics intends to achieve over the next year[Listen Now]

Jaime Garchitorena, Managing Director of UBX, joins us in this episode to share how they are spearheading Open Finance in the Philippines. Jaime will share his early hustles being an artist and how we eventually got into corporate and in finance. He will also share how he got into UBX and how he spearheaded their Bux platform and eventually became the Managing Director. Jaime also shares the exciting things they're doing in UBX like Seekcap and how they are helping more Filipinos get access to credit. This episode is brought to you by Qapita, PayMongo, SeekCap, and GoTyme Bank.For show notes, go to Hustleshare.comHustleshare is powered by PodmachineListen to our brand new podcast: Founders Only HERECheckout Founders Only on these Platforms:Youtube: https://www.youtube.com/@hustlesharepodcastSpotify: https://open.spotify.com/show/6u01gZ1nBXSHOw2oxoBQWC?si=d3062142ecd345d5Apple Podcast: https://podcasts.apple.com/ph/podcast/hustleshare-presents-founders-only/id1689672917Hustleshare AI: https://ai.hustleshare.com/ Hosted on Acast. See acast.com/privacy for more information.

Senior executives and heads discussed how banks and financial institutions redefine business models to be more inclusive, innovative, and resilient to volatile market conditions for SMEs. They also highlighted the opportunities and challenges of utilizing a composable design to succeed in the market. Aswin phlaphongphanich of DeeMoney, Edu Trinidad of UBX, Frankie Wai of Temenos, Prashant Chauhan of Tata Capital, Sokha ROS of SBI LY HOUR Bank, and Srinivasan Shanmuganathan ( Shan ) of Standard Chartered shared their perspective on how can the composable design enable financial institutions to better address the needs of SMEs. Composable designs through interconnected components of microservices which can be assembled and reassembled quickly to go live fast are going to be the future. They also discussed how traditional banks have to evolve to compete with new market entries amid technological disruption and regulatory changes. To serve smaller-sized MSMEs a change of the game is needed in distribution and infrastructure. Wai discussed that new players keep raising the bar for customer experience. Whenever there is a new positive experience regardless of industry, customers expect the same standards. Sokha pointed out that most incumbents only look at the top SMEs which leaves MSMEs behind. Aswin revealed that the pandemic brought to the fore pain points on the payments side where MSMEs were unable to reach their banks for remitting fund transfers within and across borders, and were facing huge forex volatility impacting the cash flow and liquidity of MSMEs. Trinidad commented that embedded finance allows the ability to provide quick and specific solutions right to the customers. Shanmuganathan noted that infrastructure is more about accessibility not about technology enablement and how to gain access and speed to market that is critical. API connectivity and fintech collaboration are critical in building a self-service model for MSMEs to empower them to pick and choose what they need. He also highlighted that the biggest challenge with open banking is that there are many regulatory market restrictions, including how to utilize data that have not yet been addressed. To create service and product flexibility at the front end, Prashant shared that for agile capabilities one needs to build a layer on top of legacy systems, an open network of APIs for various functions. But to succeed in this, the most important part is to change the process, the policies and the digital mindset of the company accordingly. In the future, there is no brand loyalty only service loyalty and those FIs that serve the best and provide the best rates in the shortest time will win the race Key discussion points: How can the composable banking approach address the needs of SMEs and promote financial inclusion? How can traditional banks evolve to compete with challenger banks amid technological disruption and regulatory changes in digital payments and lending? How do organisations build and redefine business models to be more inclusive and resilient to volatile market conditions? How organisations are balancing corporate responsibility and profitability to achieve greater stakeholder satisfaction and engagement?

Join Brad as he interviews co-founder and Managing Director of UBX, Tim West. Listen in to this fitness industry success journey from Tim's humble beginnings as a Personal Trainer, right through to the owner of a global phenomenon. Also hear how Warner Bros were banging on the doors of UBX to partner on the release of the Movie ‘Creed 3'!

Serial entrepreneur Bjorn Pardo of AHG Lab joins us in this episode to share how AHG Lab aims to create startups that solve big problems in the Philippines. Bjorn will share his early ventures in selling in eBay and how that led him to go to the Philippines to launch Xend. He will also share the key learnings bootstrapping Xend and operating it for 16 years which sprung multiple products and several exits. Bjorn also shares the experience he got working with UBx and other startups that prepared him for his new journey creating new startups with AHG Lab.This episode is brought to you by PDAX. Join PDAX here: podlink.co/hustlesharepdaxFor show notes, go to hustleshare.comHustleshare is powered by Podmachine Hosted on Acast. See acast.com/privacy for more information.

Learn why functional strength training is critical to healthy aging in this interview with Betsy Spieler, PT. Betsy is a co-founder of the UB Stronger 55+ small group strength training program out of the UBX gym in Omaha, NE. Adequate strength training and protein intake are essential to maintain healthy muscle mass, strength, power, and endurance as you age. These are important to prevent falls and fractures. As physical therapists, we've seen far too many times a fall being the beginning of the end of someone's quality of life. September was fall prevention awareness month and we wanted to highlight several key things you can do to reduce your risk of falls. Highlights From This EpisodeHow the curriculum of UB Stronger 55+ was developed and what it looks like.Findings from the UB Stronger 55+ pilot program, and what they mean. What types of education are provided outside of physical training?Overcoming fear of injury in older adults. The importance of personal responsibility for your own health.Treating the whole person, not just the impairment.Nutrition and fall prevention.The metrics that UBX tracks and what they've found. Subscribe & ReviewSubscribing and leaving a rating and review are important factors in helping the Reshape Your Health Podcast and the YouTube Channel reach more people. If you haven't already subscribed, please do that today.We would also be grateful if you left a rating and review, too. In your listening app, scroll to the “Ratings and Reviews” section, then click “Write a Review” and let us know what you enjoy about our show. We appreciate you taking the time to show your support. Thank you!Resources From This Episode>> Join Zivli>> Book a Free Zivli Discovery Call>> Freebie: Weight Loss Mindset Audio Training>> Freebie: The Ultimate Food Guide>> UB Stronger 55+ Program>> UB Stronger 55+ email: ubstronger55+@gmail.com 

A number of Filipinos across our archipelago remain unserved; if not, underserved by the banking industry. According to the Bangko Sentral ng Pilipinas, 181 of our cities and municipalities do not have banks; instead, they have microfinance NGOs, pawnshops, e-money agents, and cash agents offering financial services. In other places, people rely on their locally-present rural banks. This episode, we speak with UBX, a financial technology company that wants to improve access to banking services across the archipelago, tapping into the networks of rural banks and other financial services providers, and offering itself to them as a banking-as-a-service platform.

#MTG Pro Sam Black talks about UBx decks in #MTGDMU Sponsor: Game Grid Lehihttps://store.gglehi.com/?ref=draftarchCoupon Code: 10% off with code DraftPro10https://store.gglehi.com/discount/draftpro10?ref=draftarch

#MTG Pro Sam Black talks about UBx decks in #MTGDMU Sponsor: Game Grid Lehihttps://store.gglehi.com/?ref=draftarchCoupon Code: 10% off with code DraftPro10https://store.gglehi.com/discount/draftpro10?ref=draftarch

Michael Jordan joined 12RND in 2017 at 5 studios and has helped grow the brand to 94 studios today (and counting), as well as overseeing a major rebrand recently to UBX. With great success comes a lot of lessons, which Michael was happy to share openly in this episode.   PARTNERS SUPPORTING THE SHOW Glofox- Innovative and comprehensive fitness management software⮕ Glofox Website ClassPass- The app for all things fitness, spa & beauty⮕ https://classpass.com/partners MyZone- Industry-leading heart rate monitor and online social platform for gyms and studios⮕ https://www.myzone.org/ Maya Agency- Branding, marketing and web development for fitness & wellness businesses⮕ https://maya.agency/   GUEST RESOURCES UBX Boxing + Strength Own a UBX Michael Jordan LinkedIn   SHOW RESOURCES Jack Thomas on LinkedIn Fitness Business Asia Website Fitness Business Asia Instagram

Sign up for my Daily Fintech or Daily Digital Banking Newsletters here. Check out my latest podcast episode below: Welcome to another episode of our Daily Fintech Podcast. This podcast episode is sponsored by PayRetailers. PayRetailers is a Spanish company and a leader in online payment services dedicated to creating a fast and simple payment process for merchants and shoppers. The company offers a full range of payment solutions to help e-commerce companies accept online payments through a single API. By accepting local payment methods, PayRetailers allows anyone to make online purchases, even if they don't have credit or debit cards. Visit www.payretailers.com THE NEWS HIGHLIGHT OF THE DAY IS Zip Co and Sezzle have mutually agreed to cancel their merger. This is due to the current industry climate which has seen the financial prospects of both companies severely damaged. JUST IN: Paris-based BlackFin Capital Partners, private equity and venture capital firm focusing on financial services, announced on Monday the second closing of its Tech 2 fund at €350M. ALSO: For the first time in history, remittances to Mexico surpassed $5B USD in May 2022, according to data from Banxico. The average remittance value is $401 USD, and 5%+ of all households in the Mexico receive one. FURTHERMORE, Chilean insurance-tech startup Betterfly plans to expand overseas after its latest funding round swelled its valuation to $1 billion. The company is preparing to begin operations in seven new markets in 2022 -- Mexico, Colombia, Argentina, Peru, Ecuador, Panama and Costa Rica –- using the proceeds of its Series C round, according to founder and Chief Executive Officer Eduardo della Maggiora. WHAT ARE THE LATEST INSIGHTS? Small and Medium Businesses (SMBs) make up an essential value pool for the banking and financial services industry, accounting for more than 90% of all companies and more than 50% of jobs worldwide. Despite being such an important value pool, SMBs have remained an underserved market for their business banking needs. The finance gap for formal SMBs in emerging markets is estimated to be USD 5 trillion. LET'S HEAR ALL ABOUT MERGERS AND ACQUISITIONS: M2P Fintech, an Asian financial Infrastructure company recently announced it has acquired Finflux, a cloud lending platform. AS FOR PARTNERSHIPS The Philippine Postal Corporation (Post Office) has partnered with UBX, a fintech unit created by the Union Bank of the Philippines, to launch a capacity development project which will allow the postal agency to offer financial services. Agrotoken, a global tokenization platform focused on agrocommodities, has teamed up with Pomelo and Algorand as strategic allies for the implementation and development of a card designed for the agricultural sector.

In this episode of the Asia Pacific Series, we speak to John Januszczak, President & CEO of UBX, a FinTech venture studio created by the Unionbank of the Philippines. UBX was initiated to positively impact financial inclusion and business growth through technology. Founded in 2018 by Union Bank of the Philippines, UBX operates in Singapore and the Philippines; recognized as the Fastest Growing Fintech Company in South East Asia 2020 by UK-based Global Brands Magazine and Best Digital Community Impact Initiative in South East Asia 2020 by Capital Finance International (CFI.co).  Originally from Canada, his degree in Astrophysics and experience in telecom, commercial software, banking and insurance industries provides a unique and well-rounded perspective on digital platforms. Prior to UBX, John served as the Chief Operating Officer of Manulife Philippines. We talk about: UBX's partnership with the Cardano Foundation The opportunity for building the underlying financial pipes for the Embedded Finance economy The opportunity for Venture Building in the Philippines Understanding the Crypto opportunity in the Philippines Building FinTech in the Philippines

Franco Espinos of Bux, a portfolio company of UBX, joins us in this episode to share how startups and businesses can take advantage of Bux's powerful payment processing methods. Franco will also share his journey coming from corporate to how he became a Product Owner in UBX to lead Bux. He'll also share tips for aspiring founders looking to join venture builders or venture funds as a pathway to launch startups. This episode brought to you by B21. For show notes, go to hustleshare.com Check out Bux here: http://bit.ly/BuxHustleshareSignup Download Kumu now: https://podlink.co/kumu-hustleshare Hustleshare is powered by Podmetrics

John Januszczak of UBX joins us in this episode to share how Unionbank created a venture studio and venture fund to help startups and businesses in the Philippines. John will also share his unique early hustle in Astrophysics which eventually led him to celebrated career tech and finance. He will also share the startups that UBX have created and what they look for in founders they want to support and in startups that they want to fund. This episode brought to you by B21. For show notes, go to hustleshare.com Hustleshare is powered by Podmetrics Check out the UBX portfolio: i2i SeekCap UBX Sentro Bux

And so we have reached the end of one chapter. We wish Danny Godspeed and look forward to beginning the next chapter of UBX. See ya soon!

Homeotic (Hox) genes are transcription factors that dictate the development and compartmentalization (regionalization) of body parts in animals along the anterior-posterior (head to tail) axis. Using various insects and crustaceans, Dr. Nipam Patel studies how alterations in the expression of Hox genes could explain the evolution of specialized body parts in arthropods. Patel describes the spatially restricted patterns of Hox gene expression, explains the effects of Hox gene deletions, and how these phenotypes help us understand the manner in which Hox genes act to control the insect body plan. Taking a closer look at the pattern of the Hox gene Ultrabithorax (Ubx) in different insects, Patel summarizes the discovery that what drives changes in the number of wings during insect evolution is the not changes in the expression pattern of Ubx, but the regulation of its downstream gene targets.

In the second lecture, Patel describes the work of his lab to expand the studies of Hox gene function to other arthropods.  Patel describes the development of specialized body parts in crustaceans, and describes the transition between feeding to locomotor appendages. Using the beach hopper, Parhyale, his laboratory, in collaboration with the laboratory of Michalis Averof, showed that Ubx controls the boundary and transition between feeding and locomotor appendages during development.

In his third talk, Patel explores the function of additional Hox genes in the development of crustacean body plans. Using CRISPR-Cas9 genome editing, his laboratory has characterized the expression and function of six of the nine Hox genes in Parhyale, and describes the combinatorial role of Ubx, abdA, and AbdB in the development of specialized appendages in this species, and how changes in the regulation of abdA is responsible for several morphological transitions during crustacean evolution.

Homeotic (Hox) genes are transcription factors that dictate the development and compartmentalization (regionalization) of body parts in animals along the anterior-posterior (head to tail) axis. Using various insects and crustaceans, Dr. Nipam Patel studies how alterations in the expression of Hox genes could explain the evolution of specialized body parts in arthropods. Patel describes the spatially restricted patterns of Hox gene expression, explains the effects of Hox gene deletions, and how these phenotypes help us understand the manner in which Hox genes act to control the insect body plan. Taking a closer look at the pattern of the Hox gene Ultrabithorax (Ubx) in different insects, Patel summarizes the discovery that what drives changes in the number of wings during insect evolution is the not changes in the expression pattern of Ubx, but the regulation of its downstream gene targets.

In the second lecture, Patel describes the work of his lab to expand the studies of Hox gene function to other arthropods.  Patel describes the development of specialized body parts in crustaceans, and describes the transition between feeding to locomotor appendages. Using the beach hopper, Parhyale, his laboratory, in collaboration with the laboratory of Michalis Averof, showed that Ubx controls the boundary and transition between feeding and locomotor appendages during development.

In his third talk, Patel explores the function of additional Hox genes in the development of crustacean body plans. Using CRISPR-Cas9 genome editing, his laboratory has characterized the expression and function of six of the nine Hox genes in Parhyale, and describes the combinatorial role of Ubx, abdA, and AbdB in the development of specialized appendages in this species, and how changes in the regulation of abdA is responsible for several morphological transitions during crustacean evolution.

This episode is featuring Simon Driscoll, founder of UBX skin Care. He spent years researching simple natural ingredients that have proven over the millennia to work effectively with different skin types.

 "The Philippines means opportunities, whether personal or professional. It really is a learning experience in the broadest sense of the term." -John Januszczak    Oli and Paul are joined by UBX President and CEO, John Januszczak. Share in John's thought-provoking stories about his love and passion for The Philippines, the cultural, food and how the local economy is emerging as a power within the FinTech industry. John explains how he and his family have settled into way of life here and how now The Philippines is his home.    He also shared the many digital platforms that UBX are involved in, making banking easier for the local Filipinos. Such platforms as BUX.PH/SENTRO.PH and SEEKCAP.PH/i2i.ph was created with one common theme at the heart of their design, "Let's making banking easier for everyone'. John summed up his experiences here in one sentence "

Today is a long one.  We go over most of the cards that we are excited about or think are interesting in Core 2020.  Why start by talking about what a core set is and why the exist.  Then we talk about a return of an old card type "color hosers."  Then starts the deep dive on cards.  After going over the cards, we wanted to, we turn it over to you the listeners.  We answer your twitter and facebook questions about the new set.  We cover individual cards, interactions and prerelease.  Then we talk about the shifting Arena meta and how we live in a UBx world. Rules Update - For Embodiment of Agonies, the split cards have the mana cost of the combined halves.  They do not count as two different mana costs. What is a core set? - 1:51 Core Set Color Hosers - 4:54 Core 2020 Hate Cards - 9:32 The rest of the Leylines - 12:45 Core 202 we like - 15:15 Sorin - 17:07 Mu Yangling - 20:34 Chandra, Acolyte of Flame - 22:16 Chandra, Awakened Inferno - 25:21 Vilis, Broker of Blood - 27:35 Blight Beetle - 30:49 Shifting Ceratops - 31:56 Elvish Reclamer - 34:29 Drawn from Dreams - 39:29 Rotting Regisaur - 43:18 Marauding Raptor 46:45 Field of the Dead - 50:45 Viewer Questions - 52:52  Embodiment of Agonies - 53:00 Bag of holding - 57:00 Goblin Ringleader - 1:01:21 Scry Lands - 1:03:31 Brought Back - 1:07:50 The Cavalier Cycle - 1:10:52 Lotus Field - 1:19:18 Top 3 cards from Core 2020 - 1:23:20 Post-Rotation Decks - 1:24:27 What to play at pre-release - 1:26:51 Something about Arena - 1:31:19 Facebook: Casual Try Hard MTG Twitter: @casualtrypod Email: casualtryhardmtg@gmail.com  You can find us on the Apple podcast app, Google Play, Podbean, Soundcloud, Spotify or Stitcher, just search casual try hard. Music by Juan Rodriguez II ZeeManlove.com  

With Grand Prix: New Jersey on the horizon, episode 32 of #EverydayEternal finds Sam Craven (@thecravenone) and Matt Pavlic (@SDE_Matt) discussing the top Legacy decks from both Legacy Champs and the StarCityGames Legacy Open in Minneapolis. Included in the conversation is how to handle these decks, what metagame changes these decks could bring, and how to deal with those change. 0:00 Intro, and the top decks from Eternal Weekend 0:02:30 UR Delver is really coming into its own 0:05:59 UB Tezzerator 0:11:30 Jund 0:21:00 Surprises in the Top 32: Increased presence of combo, strength of Tabernacle, and fewer StoneBlade decks than expected 0:30:32 Dimir Charm in UBx decks 0:33:55 Punishing Maverick with Domri Rade and Voice of Resurgence 0:39:48 Common themes and how to fight them: low toughness, high converted mana costs on key cards, and greedy manabases 0:47:46 SCG: Minneapolis full of interesting decks, and Slivers 0:54:27 UR Painter and “Rest in Pieces” 1:00:52 Dragon Stompy 1:05:34 Plays of the week 1:09:01 GP: New Jersey information and outro – Legacy Champs Top 32 Decks – StarCityGames Legacy Open Minneapolis Top 16 Decks Matt's suggested lists for GP New Jersey: NEO Maindeck 4 Deathrite Shaman 4 Dark Confidant 4 Spirit of the Labyrinth 4 Stoneforge Mystic 4 Thoughtseize 2 Inquisition of Kozilek 4 Swords to Plowshares 2 Zealous Persecution 3 Liliana of the Veil 3 Lingering Souls 2 Sensei's Divining Top 1 Umezawa's Jitte 1 Sword of Fire and Ice 1 Sword of Feast and Famine 1 Sorin, Lord of Innistrad 4 Wasteland 3 Verdant Catacombs 4 Marsh Flats 1 Windswept Heath 3 Scrubland 1 Bayou 3 Swamp 1 Plains Sideboard 2 Rest in Peace 3 Pithing Needle 2 Disenchant 3 Thalia, Guardian of Thraben 2 Timely Reinforcements 1 Zealous Persecution 2 Tidehollow Sculler Esperblade Maindeck 4 Force of Will 2 Thoughtseize 2 Counterspell 3 Swords to Plowshares 2 Supreme Verdict 2 Engineered Explosives 4 Brainstorm 2 Dimir Charm 3 Jace, the Mind Sculptor 2 Dig Through Time 2 Snapcaster Mage 1 Notion Thief 4 Stoneforge Mystic 1 Batterskull 1 Umezawa's Jitte 1 Sword of Fire and Ice 3 Lingering Souls 1 Karakas 4 Flooded Strand 4 Polluted Delta 2 Academy Ruins 3 Tundra 2 Underground Sea 1 Scrubland 3 Island 1 Swamp 1 Plains Sideboard 3 Meddling Mage 2 Rest in Peace 2 Zealous Persecution 2 Vendilion Clique 2 Grafdigger's Cage 2 Pithing Needle 1 Notion Thief 1 Swords to Plowshare Junk Maindeck 4 Deathrite Shaman 1 Sylvan Safekeeper 4 Dark Confidant 1 Scavenging Ooze 3 Vampire Hexmage 1 Scryb Ranger 1 Gaddock Teeg 4 Knight of the Reliquary 2 Green Sun's Zenith 3 Cabal Therapy 3 Thoughtseize 2 Life from the Loam 1 Living Wish 4 Abrupt Decay 3 Swords to Plowshares 1 The Tabernacle at Pendrell Vale 1 Dark Depths 1 Thespian's Stage 4 Wasteland 1 Cabal Pit 1 Urborg, Tomb of Yawgmoth 4 Verdant Catacombs 2 Windswept Heath 1 Marsh Flats 3 Bayou 2 Scrubland 1 Savannah 1 Dryad Arbor 1 Swamp Sideboard 1 Bojuka Bog 1 Dark Depths 2 Gaddock Teeg 1 Qasali Pridemage 1 Karakas 2 Krosan Grip 3 Pithing Needle 2 Engineered Explosives 2 Chains of Mephistopheles

The UBX Live Show renders another slammin' show! The guys discuss the NFL Lockout, the death of pop star Amy Winehouse, and the elderly woman arrested in Dallas for being drunk but she wasn't even drunk! R&B Star Rantz Davis calls and Miss Louisiana 2011 hangs out as well!

The goal of the work was to address the role of higher order nuclear architecture in the functional regulation of endogenous genes and transgenes in different species. In the first part of the work, 3D distance measurements were performed to analyze in WT flies and in different transgenic lines of Drosophila melanogaster (Cavalli and Paro, 1998; Zink and Paro, 1995) the nuclear localization of endogenous genes and transgenic constructs containing the Polycomb Response Element (PRE) Fab-7 relative to the nuclear periphery and heterochromatin. Transgenic constructs containing the Fab-7 element and three endogenous genes, Abd-B, sd, and Ubx, were first analyzed at their inactive state. The results showed that they were preferentially associated with the nuclear periphery and did not display specific associations with heterochromatin. The localization of the transgenic Fab-7 element was further analyzed at different states of activity. Activation of the transgenic Fab-7 element resulted in frequent (up to ~50%) association with the boundary of the heterochromatic domain. The percentages of such associations were tissue- and fl y line-dependent. Further investigations of the boundary of heterochromatin showed that this region has a complex organization, where euchromatic sites enriched in the active form of RNA pol II and trimH3K4, sites enriched in dimH3K4 and Pc-binding sites, as well as pericentromeric satellite DNA are exposed and juxtaposed towards each other. The concentration and specific architecture of such sites at the boundary of heterochromatin might help to maintain the equilibrium between activation and repression at this boundary. This specific environment might be favourable for maintaining PREs in the active state. I also investigated in three transgenic lines whether endogenous and transgenic copies of the Fab-7 element interact physically, using 3D distance measurements. In five tissues analyzed, no pairing between endogenous and transgenic copies of the Fab-7 element was observed. Also enhancement of Pc-mediated silencing did not induce pairing. Additionally, the general organization of Pc-binding sites was addressed in six larval tissues. We used different methods of microscopy and image analyses to count the numbers of Pc foci in nuclei from these tissues. Our data did not indicate clustering of Pc-binding sites and formation of so called „Pc bodies“. However, corresponding analyses are not without problems at the current stage of methodology and results must be interpreted carefully. Together with the results of previously published studies, which investigated pairing between PREs (Bantignies et al., 2003; Vazquez et al., 2006), my data demonstrated that such pairing is a highly tissue-specific phenomenon and is likely not involved in the regulation of PREs in various tissues. Activity-related positioning of transgenes was also addressed in transgenic porcine cell lines (Hofmann et al., 2003). Results of 2D erosion analyses showed that the LV-PGK transgene was associated with the nuclear periphery in its inactive state, while it occupied more interior positions in its active state. This corresponds to my results obtained with transgenic Drosophila lines. My data also suggested that the active LV-PGK construct might be associated with heterochromatin in one case. However, further experiments would be necessary to confirm such associations. The results obtained with Drosophila and porcine cells suggested conserved mechanisms for tethering inactive loci to the nuclear periphery. These were further addressed using the human CFTR locus as a model, which is closely associated with the nuclear periphery in its inactive state (Zink et al., 2004). The question was addressed whether Tpr, a protein associated with the nuclear basket, plays a role in the perinuclear localization of the inactive CFTR locus. CFTR showed a high degree of association with the nuclear periphery in control cells in accordance with previous data (Zink et al., 2004). After knock-down of Tpr via RNAi CFTR displayed a more interior positioning. This suggests that Tpr is involved in the organization of inactive gene loci at the nuclear periphery. Moreover, since Drosophila Tpr has a high level of homology to the mammalian Tpr (Zimowska et al., 1997) and as it has been shown that the yeast Tpr homologs Mlp1 and Mlp2 are involved in tethering of inactive loci to the nuclear periphery in yeast cells (Galy et al., 2000), it is possible that Tpr is a part of a conserved mechanism anchoring inactive loci to the nuclear periphery in eukaryotic cells.