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Guest: Dr. Filipa Simões is a Group Leader at the University of Oxford and Co-Director of the Oxford Organoid Hub. She discusses how macrophages shape heart development, repair, and regeneration, and how cellular crosstalk within the cardiac niche influences tissue outcomes after injury. Using zebrafish models, stem cell–derived cardiac organoids, and spatial genomics approaches, she explores the molecular signals that govern macrophage identity and function, with the goal of uncovering new strategies to promote cardiac regeneration and limit fibrosis. Featured Products and Resources: Join us at ISSCR and discover the breakthroughs and technologies you can take straight back to your lab. Enter to win 350 US dollars or equivalent towards refreshments to fuel your next journal club. The Stem Cell Science Round Up iPSC Therapy for Heart Failure – Engineered heart muscle grafts derived from iPSCs increased heart wall thickness and improved cardiac function in patients with heart failure. Inflammatory Memory in HSCs – A distinct human HSC subset retains inflammatory memory, influencing blood production, aging, and disease risk. Organoid-Mediated Vision Recovery – Transplanted human retinal organoids partially restored vision after complete optic nerve transection in rats. Improving HSPC Gene Therapy – A new selection strategy enriches precisely edited hematopoietic stem cells while reducing unwanted genomic alterations. Photo Reference: Courtesy of Filipa Simões. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Samuel Nobs is an Assistant Professor and Group Leader at the Institute for Research in Biomedicine in Switzerland. He discusses how microbes in the lungs and gut may shape respiratory immunity and influence susceptibility to infections and chronic lung diseases. He highlights his lab's work to uncover the mechanisms behind these interactions using microbiome analysis and advanced experimental models. Featured Products and Resources: Download a practical guide on everything you need to know about cell isolation techniques. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Rabbit Immunity Evolves – Wild rabbits rapidly evolved resistance to myxoma virus through changes in highly diverse MHC immune genes. Antifungal Receptors Improve Vaccines – Targeting antifungal immune receptors with a mannan-based adjuvant boosts the strength, durability, and variant coverage of mRNA vaccine responses. Mapping Tumor Macrophage Diversity – Scientists have revealed how diverse tumor-associated macrophage subtypes promote tumor growth, immune suppression, and metastasis through interactions within the tumor microenvironment. Dietary Soy Shapes Immunity – Dietary soy shapes the gut microbiome to boost IgA-mediated immunity and enhance protection against intestinal infection in early life. Image courtesy of Dr. Samuel Nobs. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Vijay Sankaran is a Professor at Harvard Medical School and Investigator at the Howard Hughes Medical Institute. He discusses how his lab uses human genetics and stem cell biology to uncover mechanisms regulating hematopoiesis and blood disease, including the discovery of key regulators such as BCL11A and HOTSCRAMBL. He also explores how advances in genome editing, stem cell engineering, and single-cell genomics are shaping new therapies for disorders such as sickle cell disease, thalassemia, and leukemia, while highlighting the challenges of translating these breakthroughs into scalable patient treatments. Featured Products and Resources: Join us at ISSCR 2026 to catch the latest breakthroughs Learn to confidently apply the ISSCR Standards for Human Stem Cell Use The Stem Cell Science Round Up Building Pancreatic Cancer Models – A stem cell-derived organoid model reveals genetic and epigenetic mechanisms driving human pancreatic cancer initiation. Functional Cancer Stem Cell Assays – Researchers have developed a microwell platform that enables rapid enrichment of breast cancer stem cells for personalized drug testing. Human Pacemaker Assembloids – A human cardiac assembloid model recreates neural control of pacemaker activity and atrial conduction. Photo Reference: Courtesy of Dr. Vijay Sankaran. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

New research suggests that low-dose peptide therapy may help calm histamine-driven inflammation and mast cell activation in people with stubborn symptoms like food reactions, brain fog, fatigue, flushing, itching, hives, bloating, and digestive distress. In this episode, Dr. Ruscio explains how the gut, histamine, and mast cells are connected, what the latest human research shows, and why this approach may help some patients who haven't fully responded to diets, supplements, or other natural therapies.  

Guest: Dr. Tullia Bruno is an Assistant Professor at the University of Pittsburgh. She discusses how B cells and tertiary lymphoid structures shape anti-tumor immunity within solid tumors, challenging the traditional T cell–centric view of cancer immunology. She highlights how these immune niches influence responses to immunotherapy, the importance of spatial organization within the tumor microenvironment, and emerging strategies to therapeutically induce tertiary lymphoid structures to improve cancer treatment. Featured Products and Resources: Subscribe for a chance to win a pair of STEMCELL science socks. Request a free EasySep EV isolation kit sample to try in your own lab. The Immunology Science Round Up Feeding Boosts T Cell Immunity – Postprandial metabolism enhances T cell fitness and improves effector and CAR-T cell function through chylomicron-driven metabolic reprogramming. Chemokines Control T Cell Priming – CCR7 signaling limits CD8+ T cell interactions with dendritic cells to preserve effective effector and memory responses. Helminths Boost Offspring Immunity – Maternal helminth-driven microbiome changes protect offspring from respiratory viruses through the metabolite indole-3-propionic acid. Enhancing CAR T Persistence – CAR-modified stem-cell memory T cells show improved persistence, expansion, and anti-tumor responses compared to standard CAR T cells. Image courtesy of Dr. Tullia Bruno. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Meenal Datta is an Associate Professor at the University of Notre Dame and leader of the Tumor Immune Microenvironment Mechanics (TIME) Lab. She discusses how mechanical forces within tumors shape cancer progression and immune responses, with a focus on glioblastoma. She highlights how immunomechanics and mechanobiology influence tumor growth, treatment resistance, and immune cell function, and explores how space-based research and microgravity models can uncover new insights and therapeutic strategies for cancer. Featured Products and Resources: Join us at ISSCR 2026 and be part of the global conversation shaping the future of stem cell research. Strengthen reproducibility of hPSCs with this free, on-demand training course offered by STEMCELL Technologies and the ISSCR. The Stem Cell Science Round Up Why the Heart Resists Cancer – Researchers have discovered that mechanical load in the heart suppresses cancer cell proliferation via mechanotransduction and chromatin remodeling. HOTSCRAMBL Shapes Stem Cell Fate – A genetic variant disrupts the lncRNA HOTSCRAMBL, reducing HSC self-renewal and impairing leukemia growth. AI-Driven Drug Repurposing – Deep learning and organoid screening identified azole drugs that rescue neuronal defects in Leigh syndrome. Modeling the Menstrual Cycle – An organoid-based model recreates the menstrual cycle and identifies WNT7A as key for endometrial regeneration. Photo Reference: Courtesy of Dr. Meenal Datta. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

In this episode of the OnTrack Podcast, Zach Peterson sits down with Gabriel Guglielmi, VP of Global Product Management at Infinite Electronics, to explore one of the most disruptive shifts in electronics today: the rise of unmanned systems. From group one commercial drones to group five collaborative combat aircraft, Gabriel breaks down how the same revolution that transformed the space industry through SpaceX is now reshaping aerospace, defense, public safety, and consumer delivery. Learn why interconnect technology has become just as critical as semiconductor performance, and how a new generation of startups is compressing decades-long development cycles down to mere months.   The conversation digs deep into the supply chain challenges facing US and allied drone manufacturers, the FCC's part 108 regulations, the Department of War's Drone Dominance program, and why companies like Neros and Infinite Electronics see massive opportunity in rebuilding a friendly-nation supply chain. Gabriel also shares his thoughts on humanoid robotics, counter-drone systems, drone racing, agricultural applications, and the emerging low-altitude economy that could rival the internet revolution of the 1990s. Whether you design RF systems, work in aerospace and defense, or just want to understand where electronics is headed, this episode delivers a clear-eyed view of an industry being born in real time.  

Guest: Dr. Alfred Singer is a Senior Investigator at the National Cancer Institute Center for Cancer Research. He discusses his pioneering work on thymus development and T cell differentiation, including how T cells are selected to become CD4 helper or CD8 cytotoxic cells through MHC-restricted signaling. He shares the evolution of key concepts in the field, such as the “kinetic signaling” model of lineage commitment, and offers insights into T cell receptor signaling, regulatory T cell development, and the complexities of immune cell fate decisions. Featured Products and Resources: Receive a free 250 mL bottle of Lymphoprep plus a free SepMate tube to try in your own lab. Achieve simple, reliable EV isolation with EasySep kits from STEMCELL Technologies. The Immunology Science Round Up CEACAM6 Enables Viral Entry – Bat alphacoronavirus enters human cells via CEACAM6, revealing potential for zoonotic transmission. Cross-Dressing Drives T Cell Priming – mRNA vaccines activate CD8+ T cells through redundant dendritic cell pathways and cross-dressing mechanisms. Unlocking NK Antitumor Responses – Removing tumor Tregs unleashes NK cell responses to control cancers, including MHC I–deficient tumors. RUNX1 Controls Immune Aging – A single-cell immune aging clock identifies RUNX1 as a key regulator of T cell senescence and rejuvenation. Image courtesy of Dr. Alfred Singer Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Andrew Gaffney is Vice President, iPSC Platform at STEMCELL Technologies. In this episode, he discusses how his team is advancing pluripotent stem cell applications through high-quality iPSC line development, gene editing, organoid production, and GMP manufacturing for translational and clinical use. He also highlights key challenges in the field, including reproducibility, standardization, genetic diversity, and freedom-to-operate considerations, and explains how these factors impact the path from basic research to commercialization. Featured Products and Resources: Explore STEMCELL Technologies’ one-stop resource for organoids. Join us at ISSCR 2026 and be part of the global conversation shaping the future of stem cell research. The Stem Cell Science Round Up Transgene-Free Gastrulation Model – Scientists have produced a transgene-free stem cell model that recreates key features of human peri-gastrulation, including germ layer formation and early hematopoiesis. Engineering Antibody-Producing Stem Cells – CRISPR-edited hematopoietic stem cells generate B cells that produce durable, protective antibodies following vaccination. Safeguarding Chemical Reprogramming – Investigators have found that p53 is required for efficient chemical reprogramming by maintaining genomic stability and regulating early cell state transitions. Targeting Barriers to Cardiac Repair – Knockdown of calreticulin enhances cardiac reprogramming and improves heart repair after injury. Photo Reference: Courtesy of Dr. Andrew Gaffney Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

In April 2026, we attended IMMUNOLOGY2026, the annual meeting of the American Association of Immunologists, in Boston. We spoke with delegates about their research and impressions of the meeting, including why they attended, the most memorable science they encountered, and their experiences in Boston. Featured Products and Resources: Stay up-to-date with the latest in cell therapy news. Access a collection of checklists and guides to ensure you're prepared for your next conference. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: This special episode was recorded in front of a live audience at IMMUNOLOGY2026 in Boston. Brenda and Jason sit down with Dr. Charles Sentman, Director of the Center for Synthetic Immunity at Dartmouth College, and Dr. Giulia Escobar, Director of Pre-Clinical Research at Massachusetts General Hospital, to explore new strategies aimed at overcoming the unique challenges of treating solid tumors. They focus on real-world challenges in CAR T and NK cell therapies, including barriers to treating solid tumors, manufacturing and accessibility hurdles, and emerging applications beyond oncology, such as autoimmunity and neurodegenerative disease. Featured Products and Resources: Stay up-to-date with the latest in human immunology news. Download a free wallchart on the production of CAR T cells. Image courtesy of [Drs. Charles Sentman and Giulia Escobar] Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: In April 2026, we attended IMMUNOLOGY2026, the annual meeting of the American Association of Immunologists in Boston, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the last of five special episodes from the meeting. Jason and Brenda discuss highlights from sessions on advances in translational immunology, including immune-targeting strategies for autoimmune disease, as well as new insights into emerging technologies to map T cell receptor specificity. Featured Products and Resources: Make the most of your experience by downloading STEMCELL’s collection of tools to help you prepare for your next conference. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: In April 2026, we attended IMMUNOLOGY2026, the annual meeting of the American Association of Immunologists in Boston, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the fourth of five special episodes from the meeting. Jason and Brenda discuss highlights from talks about immunometabolic dysfunction in disease and neuroimmune interactions in inflammation and allergy. Featured Products and Resources: Learn how to isolate highly pure immune cells and efficiently process human samples with a free, on-demand course. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: In April 2026, we attended IMMUNOLOGY2026, the annual meeting of the American Association of Immunologists in Boston, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the third of five special episodes from the meeting. Brenda and Jason discuss highlights from sessions on obesity, immunometabolism, microbiome-driven immunity, antigen presentation, and new immunotherapy strategies. Featured Products and Resources: Explore the production of therapeutic CAR T cells with a a Nature Protocols wallchart. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: In April 2026, we attended IMMUNOLOGY2026, the annual meeting of the American Association of Immunologists in Boston, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the second of five special episodes from the meeting. Jason and Brenda cover new insights into microbiome–immune interactions, including bacterial influences on cancer and inflammatory disease, as well as advances in mucosal and early-life immunity. Featured Products and Resources: Improve your skills in T cell culture with a free, on-demand course on human T cell expansion. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: In April 2026, we attended IMMUNOLOGY2026, the annual meeting of the American Association of Immunologists in Boston, and recorded daily episodes discussing highlights of the previous 24 hours. Here is the first of five special episodes from the meeting. Brenda and Jason discuss highlights including advances in high-throughput proteomics and multi-omics integration for understanding immune regulation, as well as new insights into respiratory and mucosal immunology. Featured Products and Resources: Get a free wallchart summarizing the processes involved in producing CAR T cells for therapy. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Kotaro Sasaki is an Associate Professor at the University of Pennsylvania. In this episode, he discusses how his lab uses human pluripotent stem cells to model germ cell development and endocrine organs such as the testis and adrenal gland. He highlights progress toward in vitro gametogenesis, including generating spermatogonial-like cells and reconstructing testicular environments, as well as recent advances in building adrenal organoids with zonal architecture. He also explores the scientific, translational, and ethical challenges of creating functional human gametes, and emphasizes the importance of developmental biology in guiding stem cell-based approaches. Featured Products and Resources: Get a free wallchart on the derivation and applications of hPSCs. Take your human pluripotent stem cell cultures further with mTeSR™ Plus from STEMCELL Technologies. The Stem Cell Science Round Up Stage-Specific Cell Competition – Cell competition in gastruloids is stage-specific and driven by relative p53 levels during pluripotency exit. Modeling Pediatric Brain Tumors – Scientists have enabled robust generation and drug testing of patient-derived pediatric brain tumor organoids. Immune Reprogramming in Heart Failure – Engineered dendritic cells reduce cardiac fibrosis and improve heart function by modulating immune responses. Overcoming Hypoxia in Islets – Inhibiting zinc transport enhances stem cell–derived islet survival and function by improving angiogenesis and hypoxia resistance. Photo Reference: Courtesy of Dr. Kotaro Sasaki. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Amanda Lund is an Associate Professor at the NYU Grossman School of Medicine. She discusses how the lymphatic vasculature serves as a critical and dynamic interface between tissues and the immune system, challenging the traditional view of lymphatics as passive conduits. She highlights how lymphatic vessels actively regulate immune responses by controlling fluid flow, antigen transport, and cell migration during infection and cancer, and explores their emerging roles in shaping immunity and tissue biology. Featured Products and Resources: Download the free cell separation e-book from STEMCELL Technologies. Learn how to isolate highly pure immune cells and efficiently process human samples. The Immunology Science Round Up MHC I Shapes CD4 Immunity– MHC class I unexpectedly regulates CD4+ T cell cytotoxicity by protecting target cells from ferroptosis. Re-Emergence of Oropouche Virus – Scientists have mapped the resurgence and long-term burden of Oropouche virus, revealing widespread infection across Latin America. Scalable In Vivo T Cell Engineering – A new in vivo CRISPR-based system enables precise, stable generation of CAR T cells. Gut–Brain Axis in Autoimmunity – Intestinal epithelial cells initiate autoimmune neuroinflammation via TH17 cell responses that migrate to the central nervous system. Image courtesy of Dr. Amanda Lund. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Aitor Aguirre is an Associate Professor at Michigan State University and Director of the Stem Cell Core. In this episode, he discusses how his lab uses pluripotent stem cells and cardiac organoids to model human heart development and disease. He highlights the role of self-organization and bioengineering in building complex heart models, including assembloids with immune and neural components, and their applications in studying conditions like atrial fibrillation. He also shares perspectives on open science, collaboration, and training the next generation of scientists. Featured Products and Resources: Get a free wallchart on the directed differentiation of hPSCs. Explore STEMCELL Technologies’ collection of technical videos and webinars on neurological disease modeling. The Stem Cell Science Round Up Modeling West Nile Encephalitis – Human cerebral organoids effectively model West Nile virus encephalitis and its associated neuronal damage and inflammation. New Therapy for Leigh Syndrome – Researchers identified sildenafil as a potential treatment for Leigh syndrome. Epigenetic Landscapes of Breast Cancer – Patient-derived organoids reveal epigenetic subtypes of breast cancer, including a metastasis-specific group. Unexpected Totipotency in Hofstenia – Hofstenia embryos retain surprising totipotency and plasticity despite early fate-specifying cleavage. Photo Reference: Courtesy of Dr. Aitor Aguirre Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Mansour Haeryfar is a Professor in the Department of Microbiology & Immunology at Western University. The Haeryfar Lab is dedicated to advancing our understanding of both conventional and innate-like invariant T cell responses in health and disease. Their research focuses on mucosal-associated invariant T (MAIT) cells, with particular emphasis on exploring their therapeutic potential across a range of conditions. Featured Products and Resources: Explore scientific resources for your immunology research. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Immune Imprinting Limits Flu Protection – Early flu infections imprint the immune system, biasing later responses and reducing effectiveness against new strains. Maternal Immunity Protects Newborns – Newborns with E. coli sepsis lack protective maternal antibodies, and maternal priming can provide protection. Building the Anti-Carbohydrate Repertoire – Anti-carbohydrate antibodies develop after birth into a diverse, antigen-shaped B cell repertoire. Engineering Better CAR T Responses – CAR T resistance to checkpoint therapy can be overcome by restoring c-Jun alongside PD-L1 blockade. Image courtesy of Dr. Mansour Haeryfar. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Thorsten Boroviak is an Assistant Professor at the University of Cambridge and a member of the Cambridge Stem Cell Institute. He discusses how stem cell–based embryo models are helping researchers study early human and primate development, including implantation and gastrulation. He also talks about using primate systems such as marmoset to understand human development, the role of biomechanics and extraembryonic tissues in embryogenesis, and the ethical considerations surrounding embryo models and emerging technologies like in vitro gametogenesis. Featured Products and Resources: Explore a basic overview of organoids and resources to support your organoid culture. Explore STEMCELL Technologies’ collection of technical videos and webinars on neurological disease modeling. The Stem Cell Science Round Up Mitophagy Controls Blood Stem Cells – Embryonic blood stem cells expand while staying multipotent thanks to tightly controlled ROS levels regulated by developmental mitophagy. SLC4A3 Variants Drive Arrhythmia Risk – Mutations in SLC4A3 raise intracellular pH in heart cells, which shortens electrical signals and increases the risk of dangerous arrhythmias. HSC Dynamics After Myeloablation – After chemotherapy, blood stem cells briefly boost differentiation to rebuild the blood system before returning to normal. Modeling Duchenne Cardiomyopathy – Scientists generated heart organoids from Duchenne muscular dystrophy patient stem cells that mimic cardiomyopathy. Photo Reference: Courtesy of Thorsten Boroviak. Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Daniel Peeper is a Professor in Functional Oncogenomics at VU University Amsterdam, heading the Department of Molecular Oncology & Immunology and chairing the Research Faculty Council Board at the Netherlands Cancer Institute. His lab employs function-based, genome-wide screens and other advanced technologies to develop concepts for rational combinatorial cancer treatment, targeting both cancer and immune cells more effectively. Featured Products and Resources: Obtain highly purified cells in a single step with the Easy 250 EasySep Magnet. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Genomic Insights into EBV – Researchers used genome sequencing data to identify genetic and lifestyle factors linked to control of persistent Epstein–Barr virus (EBV) infection and its association with autoimmune diseases. Cholinergic Control of B Cells – Acetylcholine signaling in germinal center B cells helps regulate their selection and differentiation to shape high-affinity antibody responses. Targeting Persistent HIV Clones – Persistent HIV reservoir T cell clones resist immune clearance but remain vulnerable to sustained cytotoxic T cell pressure. T Cell Engagers in Autoimmunity – CD19×CD3 and BCMA×CD3 T cell engagers improved disease outcomes in patients with treatment-refractory antisynthetase syndrome and systemic sclerosis. Image courtesy of Daniel Peeper Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Drs. Shuibing Chen and Hans Clevers, members of the Steering Committee for the ISSCR Consortium on Advanced Stem Cell-Based Models in Drug Discovery and Development, discuss the need to accelerate the responsible integration of stem cell–derived models into preclinical drug development. Their conversation reflects growing regulatory and policy momentum around new approach methodologies (NAMs) and underscores the importance of rigorous standards, regulatory alignment, and cross-sector collaboration to improve reproducibility and advance more predictive, human-relevant therapies. Building on its long-standing leadership in global standards, ethics, and policy, the ISSCR is uniquely positioned to convene industry, academia, and regulators around this effort. The initiative also reflects the Society's expanding industry engagement, with industry membership increasing nearly 180% over the past five years – creating new opportunities for strategic partnerships to address shared scientific and translational challenges. Featured Products and Resources: Learn how organoids can be used to expand clinical applications of diseases and disorders.   Get a free wallchart showing how organoids are used as model systems to study infectious diseases, cancer, congenital disorders, and tissue regeneration. The Stem Cell Science Round Up Treating Frailty with Stem Cells – In a clinical trial, mesenchymal stem cell therapy improved walking distance and physical function in older adults with frailty. Combined Bone & Bone Marrow Organoids – Researchers developed a scalable iPSC-derived bone marrow organoid that models human lympho-myeloid hematopoiesis and disease. CAR-NK Progenitors Prevent Relapse – Engineered pluripotent stem cell–derived CAR-expressing NK progenitor cells reduced minimal residual disease and prevented relapse in leukemia models following chemotherapy. Whole-Body Single-Cell Mapping – Scientists have developed a 3D single-cell-resolution map of mouse organs and the whole neonatal body. Photo Reference: Courtesy of Drs. Shuibing Chen and Hans Clevers Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Ido Amit is a Principal Investigator and the Eden and Steven Romick Professorial Chair at the Weizmann Institute of Science. His lab is at the forefront of developing and applying cutting-edge single-cell genomics technologies alongside advanced computational approaches. By integrating these innovative tools in both animal models and human studies, his team uncovers the immune regulatory mechanisms and pathways that shape health and disease. Featured Products and Resources: Stay up-to-date with the latest in human immunology news. Download a free wallchart on the production of CAR T cells. The Immunology Science Round Up Modified RNA Prevents Autoimmunity – Researchers show that modified RNA from our own cells naturally blocks TLR7 and TLR8, preventing harmful immune activation. Oncolytic Virus Boosts T Cells – In glioblastoma patients, a single virus treatment helped the immune system attack the tumor. Rewiring the Immune System During Food Scarcity – When food is scarce, stress hormones rebalance the immune system to fight infection while conserving glucose and preserving immune memory. Regulating Bystander T Cells – IL-4 can dial down how strongly memory CD8+ T cells respond to infection without direct antigen stimulation. Image courtesy of Dr. Ido Amit Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Drs. Fiona Doetsch and Nozomu Yachie, Co-Chairs of the ISSCR 2026 Annual Meeting Program Committee, join the podcast to discuss what to expect at the upcoming ISSCR 2026 meeting taking place in Montreal, Canada from July 8 – 11, 2026. This is the world's largest and most comprehensive gathering dedicated to stem cell research and regenerative medicine, bringing together global leaders across basic science, technology development, translational research, and clinical application. They discuss the meeting's global focus, program highlights, and spotlight the many new invited speakers and expanded opportunities for trainees to present and network. Featured Products and Resources: Explore STEMCELL Technologies’ collection of technical videos and webinars on neurological disease modeling. Get a free wallchart showing how organoids are used as model systems to study infectious diseases, cancer, congenital disorders, and tissue regeneration. The Stem Cell Science Round Up HCMV Infection and Cholangiocyte Barriers – Scientists show that human cytomegalovirus infection induces epithelial–mesenchymal transition in cholangiocytes. Cross-Circulation for Liver Failure – Extracorporeal cross-circulation with genetically modified pig livers provided effective temporary liver support with minimal immune response in a human decedent model. How Sleep Loss Hurts the Gut – Researchers identified a sleep deprivation-responsive neural circuit that controls intestinal stem cell function. Mapping the Fetal Stem Cell Niche – Scientists demonstrate a central role of hepatoblasts in the regulation of fetal liver hematopoiesis and stem cell maintenance. Photo Reference: Courtesy of Fiona Doetsch and Nozomu Yachie Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Sharon Lewin is the Director of the Peter Doherty Institute for Infection and Immunity, where her team studies HIV. She talks about the current landscape in HIV research and treatments, and how new therapies could target latent viral reservoirs. Featured Products and Resources: Register now for IMMUNOLOGY2026! Make the Easy Choice. Try EasySep to Win! The Immunology Science Round Up Immunosurveillance in the Skin: A neuro-epithelial axis can tune regional immunosurveillance against melanoma. B Cells in Aging: B cells contributed to the age-related reduction of naive CD4 T cells. The Gut–Brain Axis in Parkinson’s: Muscularis macrophages, housekeepers of intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease. How IL-2 Signaling Regulates Inflammation: IL-2 signaling promotes the generation of IL-10pos age-associated B cells, with implications for autoimmunity and inflammation. Image courtesy of Dr. Sharon Lewin Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Joseph Wu is a Professor of Medicine and Radiology and the Director of the Stanford Cardiovascular Institute. He talks about the importance of pharmacology knowledge in drug discovery. He also discusses his early iPSC research, investigating vaccine-induced myocarditis, and embracing New Approach Methodologies (NAMs). (39:40) Featured Products and Resources: Submit your abstract for ISSCR 2026 by February 25th! STEMdiff™ Ventricular Cardiomyocyte Differentiation Kit The Stem Cell Science Round Up Autism Genes in Organoids: Research provides new insight into the convergent impact of autism spectrum disorder genetic risk on human neurodevelopment. (2:35) Pancreatic Organoid Screening: High-content screen reveals 54 compounds altering pancreatic organoid shape or differentiation. (13:15) CRISPR Screening for Tauopathies: CRISPR screens in human neurons reveal modifiers of tau oligomer accumulation. (21:03) Fixing Facial Scarring: Modulating ROBO2-EID1-EP300 signaling pathway promotes facial-like reduced fibrosis at scar-prone sites. (31:00) Image courtesy of Dr. Joseph Wu Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Rafi Ahmed is a Professor in the Department of Microbiology and Immunology and the Director of the Emory Vaccine Center at Emory University. He talks about his early work on memory T cells and its applications in autoimmune diseases and cancer. Featured Products and Resources: Register now for IMMUNOLOGY2026! Request Your Free EasySep Sample and Enter for a Chance to Win Prizes Worth Up to $3,000. The Immunology Round Up CAR T Therapy for Hemolytic Anemia: CD19 CAR T cells resulted in sustained remission in patients with multirefractory autoimmune hemolytic anemia. (3:05) How Epstein-Barr Virus and Genetics Drive Multiple Sclerosis: A new study provides a new mechanistic link for how the environmental and genetic risk factors may contribute jointly to multiple sclerosis. (8:30) Autoantigens in Multiple Sclerosis: EBNA1 CD4+ T cells can target the multiple sclerosis autoantigen anoctamin-2, establishing a link between Epstein-Barr infection and neuroinflammation. (18:45) Microbiota-Induced T Cell Plasticity: Molecular mimicry between a gut commensal and a tumor antigen can boost the efficacy of immune checkpoint blockade therapy and restrain tumor growth. (26:00) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Pinar Mesci is the Global Head of Biomanufacturing and Biotechnology at Axiom Space, where she manages a portfolio focused on biomedical research programs including stem cells, tissue engineering, disease modeling, cancer research, and DNA-inspired nanomaterials. She talks about her early career developing brain organoid models, transitioning to the space industry, and how microgravity affects biological systems. She also discusses the future of low Earth orbit research and how new technologies can be transferred back to Earth. (40:55) Featured Products and Resources: Submit your abstract for ISSCR 2026 by February 25th! Take your human pluripotent stem cell cultures further with mTeSR™ Plus from STEMCELL Technologies. The Stem Cell Science Round Up iPSC-Derived Ovarian Support Cells – Fertilo is an ovarian support cell product that improves the in vitro maturation rate of human oocytes. (1:25) Culturing HSPCs Ex Vivo – A nanoengineered 3D system improves HSPC multi-lineage differentiation and engraftment capacity. (13:30) Spinal Core Repair Scaffolds – A nanoengineered extrusion-aligned tract promotes axonal reconnection, synapse formation, and locomotor recovery after spinal cord injury. (22:50) Vascularizing Retinal Organoids – Transient vascular support enhances survival of retinal ganglion cells in organoids. (32:14) Image courtesy of Dr. Pinar Mesci Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guests: Dr. Ulrich von Andrian is the Mallinckrodt Professor of Immunopathology at Harvard Medical School and President of the American Association of Immunologists (AAI). Dr. Shekhar Pasare is Professor and Director of the Division of Immunobiology at Cincinnati Children's Hospital Medical Center. He is also the Program Committee Chair for the AAI’s annual meetings. They discuss the upcoming IMMUNOLOGY2026 meeting taking place April 15-19 in Boston. They cover highlights of the program including the Presidential Symposium, special sessions, and opportunities for trainees. (42:30) Featured Products and Resources: Submit a late-breaking abstract for IMMUNOLOGY2026! Wallchart: T Cell Nomenclature: From Subsets to Modules The Immunology Science Round Up Psoriatic Arthritis –  A two-step process involving skin-derived myeloid precursors and joint-resident fibroblasts orchestrates the spread of inflammation from the skin to the joints. (6:15) Chemotherapy and Cardiac-Resident Macrophages – DNA-damaging chemotherapy can reshape cardiac macrophage ontogeny. (13:50) Dendritic Cell Cross-Presentation – Neoantigen cross-presentation by Type 1 conventional dendritic cells can determine the immune visibility of the tumor mutational landscape. (26:00) T Cell Cross-Reactivity – Co-receptor switching generates super selective T cells that reduce the risk of lethal off-target cross-reactivity. (32:20) Images courtesy of Drs. Ulrich von Andrian and Shekhar Pasare Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

In this second episode of Get to Know Your Vet (GTKYV), I sit down with my dear friend Dr. Laurie McCauley, a board‑certified specialist in sports medicine and canine rehabilitation, for a wide‑ranging conversation.We talk openly about curiosity, humility, career crossroads, mistakes, perseverance, and the moments that shape who we become. Dr. McCauley shares how following her intuition led her to help pioneer canine rehabilitation, including the early development of underwater treadmill therapy, and how staying open‑minded continues to guide her work today.We also explore integrative and holistic approaches to healing, including rehabilitation, acupuncture, laser therapy, tuning forks, and energy‑based modalities—alongside honest reflections on family, childhood experiences, integrity, and what it really means to live and work with heart.I hope that you enjoy this episode of Get to Know Your Vet and are enjoying getting to know the humans behind the veterinary medicine!____________________________________________________Featured Products & ResourcesJointPowder: Advanced Joint, Mobility & Injury Supplement for Dogs _____________________________________________________Visit our website:https://peterdobias.com/Visit us on social media:FacebookInstagramTwitter#GetToKnowYourVet, #HolisticVeterinarian, #CanineRehabilitation, #DogHealth, #IntegrativeVeterinaryMedicine, #HolisticDogCare, #VeterinaryPodcast, #HealingDogs, #DogWellness, #BehindTheVet #DrLaurieMcCauley

Guest: Dr. Deepak Srivastava is the President of the Gladstone Institutes and Director of the Roddenberry Stem Cell Center. His lab is focused on the gene networks that guide cardiac development. He talks about their recent work investigating heart defects in Down syndrome and strategies for delivering therapies to the heart. He also talks about how to incentivize the development and commercialization of cell and gene therapies. (41:50) Featured Products and Resources: Submit your abstract for ISSCR 2026! STEMdiff™ Ventricular Cardiomyocyte Differentiation Kit The Stem Cell Science Round Up Heart and Ganglion Development – Researchers fused human sympathetic ganglion organoids and heart-forming organoids to construct functional connections between the sympathetic ganglia and the heart. (2:38) Periportal Liver Assembloids – Patient-specific periportal liver assembloids retain the histological arrangement, gene expression, and cell interactions of periportal liver tissue. (9:40) PIEZO1 and Drug-Induced Cardiotoxicity – Restoring endothelial PIEZO1 protects against tyrosine kinase inhibitor-induced hypertension and cardiac dysfunction. (19:28) Somite and Neural Tube Co-Development – Scientists developed human trunk-like structures that have morphologically organized somites and a neural tube that form through self-organized, endogenous signaling. (28:43) Image courtesy of Dr. Deepak Srivastava Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

This year, I had to privilege to meet some of you in Florida and Mallorca where I was presenting, and I also became friends with some of my colleagues vets and healers, I never met in person before.Connecting with likeminded people is the reason I'm starting something new.A new interview series I'm calling Get to Know Your Vet (GTKYV)

Guest: Dr. Jayne Danska is a Senior Scientist, Genetics and Genome Biology at the Hospital for Sick Children Research Institute. She is also Associate Chief of Research, Faculty Development and Diversity, and Professor at the University of Toronto. Her research focuses on the microbiome in type 1 diabetes. She discusses insights from longitudinal human studies and mouse models. (40:00) Featured Products and Resources: Register now for IMMUNOLOGY2026! Wallchart: T Cell Nomenclature: From Subsets to Modules The Immunology Round Up Vaccination for Anaphylaxis –  A vaccine against IgE protected against anaphylaxis in a mouse model. (2:53) How RSV Can Lead to Asthma – Researchers identified maternal allergy and neonatal RSV infection as converging Fc receptor-dependent risk factors for asthma. (9:50) Antigen Presentation for MAIT Cell Immunity – Macrophages are key for MR1 antigen presentation and MAIT cell immunity. (20:30) HIV Remission after Stem Cell Transplantation – After an allogeneic stem cell transplant, a patient discontinued antiretroviral therapy and sustained HIV remission for over six years. (27:00) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Hans Clevers is a Professor of Molecular Genetics and Distinguished Group Leader at the University of Utrecht. In this episode, he discusses snake gut and lung organoids, transitioning from academia to industry, and the challenges and complexities of creating a cell therapy. (44:26) Featured Products and Resources: Registration and abstracts are open for the ISSCR 2026 annual meeting. Receive an offer to try IntestiCult in your lab. The Stem Cell Science Round Up Computers Made From Human Brain Cells – Researchers have shown that structured neuronal firing sequences appear in spontaneous activity of human and murine brain organoids. (2:37) Organoids Replicate Vascular Pathology – Scientists have developed a blood vessel organoid model from Hutchinson-Gilford progeria syndrome-mutant hESCs. (12:01) Effects of Spaceflight on Stem Cells – Analyses of nine astronauts before, during, and after three short-duration International Space Station missions shows space-associated stem cell hallmarks of aging and resilience. (21:14) The Role of Lysosomes in HSC Aging – Reversing lysosomal dysfunction restores youthful state in aged hematopoietic stem cells. (33:25) Photo Reference: Courtesy of Hans Clevers Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Anderson is currently the Albert H. Coons Professor of Neurology at Harvard Medical School, Senior Scientist at the Brigham and Women's Hospital, Institute Member of the Broad Institute of MIT and Harvard, and Core Faculty Member of the Gene Lay Institute of Immunology and Inflammation. She talks about her research on immune regulation in cancer and enhancing anti-tumor immunity. (38:33) Featured Products and Resources: Submit your abstract now for IMMUNOLOGY2026! Download a free wallchart on the production of CAR T cells. The Immunology Round Up CAR Tregs for Atherosclerosis: Anti-oxidized low-density lipoprotein CAR Tregs reduce atherosclerotic plaque formation in mouse models. (2:20) Tumor-Reactive T Cells: Tumor-reactive CD8+ T cells can be isolated and expanded from clinical samples. (14:24) Harnessing Myeloid and Lymphoid Synergy for Immunotherapy: Myeloid-targeted immunocytokines and natural killer/T cell enhancers show potential for treating solid cancers. (18:50) Subcutaneous Fat Affects Intestinal Aging: Subcutaneous white adipose tissue dysfunction triggers aging-like intestinal dysfunctions in mouse models. (32:40) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. Thomas Vierbuchen is Assistant Professor of Developmental Biology at Memorial Sloan Kettering Cancer Center. In this episode, he talks about using PSCs to model neurodevelopmental processes. He also discusses his direct reprogramming work and his lab’s recent study on OTX2 in gastrulation. (42:02) Featured Products and Resources: Submit your abstract for ISSCR 2026! Explore STEMCELL Technologies’ collection of technical videos and webinars on neurological disease modeling. The Stem Cell Science Round Up Restoring Function After Spinal Cord Injury: In a non-human primate model of spinal injury, researchers grafted ESC-derived spinal cord neural stem cells and improved forelimb function. (2:00) Improving HSC Expansion: Inhibiting ferroptosis augments the expansion of HSCs ex vivo. (11:40) Cardiomyocytes and Macrophage Reprogramming: Injury-induced Clusterin+ cardiomyocytes promote neonatal heart regeneration by reprogramming macrophages. (21:27) Bone Marrow Organoids: A 3D in vitro bone marrow model captures phenotypic, structural, and functional features of human endosteal bone marrow niches. (33:03) Image courtesy of Dr. Thomas Vierbuchen Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Guest: Dr. George Robinson is a Principal Research Fellow at University College London, where his lab focuses on juvenile-onset systemic lupus erythematosus. He discusses current approaches to diagnosis and treatment, as well as the role of sex differences in autoimmunity. (31:20) Featured Products and Resources: Stay up-to-date with the latest in immune regulation news. Download a free wallchart on regulatory T cells. The Immunology Round Up Long-Term Allergies: Allergy-associated IgE plasma cells exhibit limited accrual in the bone marrow, and instead reside in other tissues for extended periods. (3:40) Oral Immunotherapy for Peanut Allergy: Peanut oral immunotherapy reshapes T cell responses, suppressing allergy-associated type 2 helper T cells and boosting cytotoxic type 1 helper T cells, offering clues to long-term tolerance. (9:00) Neuroprotective Microglia in Alzheimer’s Disease: The protective function of microglia is governed by the transcription factor PU.1, which becomes downregulated following microglial contact with amyloid plaques. (18:09) Autoimmunity in ALS: Researchers showed that ALS is associated with recognition of the C9orf72 antigen and mapped the specific epitopes that are recognized. (23:20) Subscribe to our newsletter! Never miss updates about new episodes. Subscribe

Greetings Glocal Citizens! We're talking about the business of teaching and learning from a design thinking perspective with my guest, fellow Stanford University alum, visionary educational leader and the founder and CEO of Roundtrip Ticket Home, an organization dedicated to helping educators reimagine school systems through design thinking, Kalimah Fergus Ayele. With almost 30 years of experience in education, her journey began as a Peace Corps Volunteer, teaching Chemistry in East Africa. Her career has spanned five countries, enriching her global perspective on learning, and bringing a deep understanding of urban educational landscapes to her transformative work. Most recently, she served as the Head of NYC Campus for The Winchendon School where she led an innovative educational oasis in Manhattan, guiding high school students through real-world learning and a unique city-wide field study program designed to connect them with their passions. In this conversation we truly experience the roundtrip journey of a little girl growing up in Brooklyn and St. Croix, building on Pan-African rooting from an early age, who manifested her new and now as a global citizen ready for her next adventure. Where to find Kalimah? @roundtrip Ticket Home (http://roundtriptickethome.weebly.com/store/c1/Featured_Products.html) On LinkedIn (https://www.linkedin.com/in/kalimah-fergus-ayele/) On Instagram (https://www.instagram.com/kalimahinkemet/?hl=en) On Facebook (https://www.facebook.com/kalimah.ayele/) What's Kalimah reading? All the Way to the River (https://www.penguinrandomhouse.com/books/707805/all-the-way-to-the-river-oprahs-book-club-by-elizabeth-gilbert/) by Eizabeth Gilbert What's Kalimah watching? aka Charlie Sheen (https://www.netflix.com/title/82024990) on Netflix Orgasm Inc: The Story of One Taste (https://www.netflix.com/title/81487901) on Netflix Other topics of Interest: About St. Croix (https://en.wikipedia.org/wiki/Saint_Croix) Sleepy Hollow, New York (https://visitsleepyhollow.com) About the United States Peace Corps (https://en.wikipedia.org/wiki/Peace_Corps) About Brooklyn's African Street Fair (https://www.blackownedbrooklyn.com/stories/international-african-arts-festival#:~:text=The%20International%20African%20Arts%20Festival,people%20from%20across%20the%20globe.) and International African Arts Festival (https://www.iaafestival.org/history) Courageous Conversation + Glenn Singleton (https://courageousconversation.com/about/glenn-singleton/#dipipopup-19366279) About the American University in Cairo (https://www.aucegypt.edu) On Montessori Education (https://en.wikipedia.org/wiki/Montessori_education) On Friends or Quaker Schools (https://www.friendsacademy.org/blog/quaker-school-5-reasons) Special Guest: Kalimah Fergus Ayele.

In this episode, I sit down with Dr. Laurie McCauley to explore how we can help our senior dogs stay happy, healthy, and mentally sharp. Dr. Laurie McCauley, DVM, is a board-certified specialist in Canine Sports Medicine and Rehabilitation, as well as an international speaker and inventor. Together, we dive into real stories and practical, science-backed strategies for preventing and managing canine cognitive dysfunction—often called doggy dementia.Join us for a heartfelt and informative conversation on the signs to look out for, how to make the senior years vibrant, and the expert tips we've used with our own dogs to ensure they thrive and enjoy life for as long as possible.You'll learn:Simple, everyday ways to boost your dog's brain health with supplements, Omega-3s, dental care, and exercise.The safest holistic treatments and what to know about medications and hormones for aging pets.How to recognize the early signs of cognitive decline and make your dog's senior years vibrant and fulfilling.Featured Products & ResourcesCanine Longevity Bundle: Essential vitamins, minerals, omega-3, probiotics and detox for dogs; natural and human-grade ingredients._____________________________________________________Visit our website:https://peterdobias.com/Visit us on social media:FacebookInstagramTwitter#caninecognitivedysfunction #dogdementia #seniordog #doghealth #dogsofinstagram #doggydementia #seniordogsrule #holisticpetcare #dogwellness #vetadvice #agingpets

Curious about a more compassionate, integrative path in veterinary care? In this episode, I talk with Dr. Ruth Roberts, a trusted advocate for holistic pet health—from acupuncture and whole-food nutrition to hormone therapy and functional medicine. Together, we explore how simple, individualized approaches—not just treating symptoms—can profoundly transform senior and sterilized dogs' well-being. We dive into real-life stories of Hiyo and Pax, discuss alternative sterilization options like ovary-sparring spays, and critique the one-size-fits-all tendencies of conventional medicine. Along the way, we reflect on the corporatization of veterinary practice and advocate for restoring its “art” with observation, humility, and healing. If you believe pets deserve personalized care that honors both their body and spirit, this episode is for you.Key HighlightsHormone Therapy – Restoring vitality in senior dogs.Spay/Neuter Alternatives – Preserving natural hormone balance.Compassionate Vet Care – Bringing back individualized healing.Featured Products & ResourcesFab4 Bundle: Complete nutritional support for your dog, made from sustainably sourced, high-quality ingredientsIs Spaying and Neutering Really the Best Choice for Your Dog? Experts Speak Out_____________________________________________________Visit our website:https://peterdobias.com/Visit us on social media:FacebookInstagramTwitter#HolisticPetHealth, #NaturalDogCare, #SeniorDogHealth, #HormoneTherapyForDogs, #HolisticVeterinarian, #IntegrativeVet, #FunctionalMedicineForPets, #DogWellness, #AlternativeSpayNeuter, #HealthyDogs

We're diving into one of the most overlooked—but surprisingly important—parts of family nutrition: drinks. In this final episode of our “What Can I Eat?” series, we're talking about what's really hydrating (spoiler: it's not just water), why juice boxes aren't the solution, and how ancestral wisdom can help us rethink what we offer our kids and ourselves to drink each day.   We chat about everything from raw milk and herbal teas to fermented beverages like water kefir and kombucha. You'll hear practical tips, stories from our own families, and the deeper “why” behind nutrient-dense drinks. If you've ever wondered what's actually worth sipping—or how to ditch the dye-filled sports drinks—this episode is packed with insight.  

We're diving into one of the trickiest—and most talked-about—topics in modern motherhood: snacks. In this episode, we unpack the cultural obsession with constant snacking, how it impacts our kids' health (and appetites), and why we've made it a priority to rethink the way we snack in our homes.   We share what's actually working in our families, how we set snack boundaries without shame, the importance of protein and fat in between meals, and why saying “no” to endless snacks isn't mean—it's loving. If you've ever felt stuck between feeding your kids something or fighting a snack battle every afternoon, this conversation will meet you right where you are.  

We're wrapping up our re-recorded “What CAN I Eat For…” series with a topic that brings out all the mixed feelings: dessert. Whether you're the “always say yes” mom, the “no sugar ever” mom, or somewhere in between, this episode is packed with honest conversation, personal stories, and practical ideas for navigating sweets in a culture that normalizes daily sugar overload.   We're talking about our own dessert philosophies, how we set boundaries with our kids, what we serve in our homes, and why saying “no” to sugar doesn't have to mean saying “no” to fun. If you've ever wondered how to handle birthday parties, grocery store freebies, or post-dinner dessert expectations, this one's for you.  

We're back with part three of our “What CAN I Eat For…” re-recorded series—and this time we're tackling the end-of-day decision that can feel impossibly heavy: dinner. Whether you're feeding toddlers, teens, husbands, or just yourself after a long day, this episode is your honest, grace-filled guide to making dinner work in real life.   We talk about the mental load of planning, how our dinners have changed over the years, the pressure to cook “the right way,” and the tension between nourishing food and realistic expectations. This isn't about rigid rules or gourmet meals—it's about grounding your family in good food, served with love and sanity.  

We're back with the second installment of our re-recorded “What CAN I Eat For…” series—this time tackling the midday meal that every mom dreads: lunch. Whether you homeschool, pack co-op meals, or just find yourself throwing random snacks on a plate at 12:42 pm, this episode is your honest, nourishing reset.   We're sharing what's actually working in our homes, how our lunch routines have evolved over time, and why “just a sandwich” doesn't cut it when it comes to energy, focus, and blood sugar. From protein-fat-fiber balance to school lunch hacks and feeding growing kids (again), this episode is full of real talk and realistic ideas to help your family thrive—without turning lunch into another stress point.  

We're kicking off the re-recorded "What CAN I Eat For…" series with one of the most relatable (and often chaotic) topics: breakfast. Whether you're a mom who wakes up ready to cook or someone who just wants coffee in silence, this episode is packed with humor, hard-won wisdom, and practical real food ideas to help make your mornings smoother—and more nourishing. We talk through how our breakfast routines have evolved, how to get kids on board with savory meals, the reality of cooking for picky eaters, the nutritional downsides of carb-heavy starts, and why protein, fat, and prep are your new best friends. If you've ever stared into your fridge at 7am wondering "what on earth do I feed these people?"—this one's for you.

In this powerful episode of the Tick Boot Camp Podcast, we sit down with Dr. Myriah Hinchey, a Lyme-literate naturopathic physician whose personal battle with Lyme disease, Babesia, and Bartonella shaped her pioneering approach to treatment. Dr. Hinchey is the founder and medical director of Tao Center for Vitality, Longevity & Optimal Health, creator of LymeCore Botanicals, and founder of LymeBytes, a global educational platform for Lyme disease. Dr. Hinchey shares how her journey from misdiagnosed childhood infections to a transformative diagnosis in her mid-30s inspired a career of advocacy and innovation in integrative Lyme treatment. Discover why she believes most chronic Lyme sufferers can heal — and how focusing on terrain, immune modulation, gut health, and targeted herbal antimicrobials makes recovery possible.

What if the key to feeling stronger at 60 than you did at 50… it isn't luck!In this episode, I am excited to share a piece of the journey that led me from veterinary medicine to developing high-quality supplements for both dogs and their humans. A story rooted in childhood memories, personal health battles, and a growing frustration with what modern medicine—and the supplement industry—often overlooks.I'll reveal how nature, nutrition, and listening to the body have all transformed my life—and how those same principles can empower you and your dog to age with gracefully.In this conversation, you'll learn:How to fuel your body with what it needs and what I personally take dailySynthetic fillers and a new path in supplement formulationWhat dogs taught me about human wellness and the body's innate healing powerWhy our food isn't what it used to be and what it means for your and your dog's health Why we invest in everything but our health—and how to shift that mindsetHow your wellness directly impacts your dog's quality of lifeWhether you're navigating your own health challenges, rethinking the supplements you rely on, or simply striving to age with intention, this episode offers a raw, inspiring roadmap to reclaiming vitality—for you and your dog.Give your dog a hug from me, and thanks for listening!_____________________________________________________Featured Products & ResourcesFab4 H+ Bundle - Complete human nutritional support pack with top-quality natural and fermented supplementsJointButter® H+ - Advanced Joint, Mobility & Injury Supplement for HumansLiverTune® H+ - Certified Organic Naturally Fermented Liver Support_____________________________________________________Visit our website:https://peterdobias.com/Visit us on social media:FacebookInstagramTwitter#HolisticHealth #VeterinaryWisdom #HealthyHumansHealthyDogs #SupplementsThatWork #NaturalHealing #LongevitySupport #DogWellness #HumanSupplements #HealthyAt60 #DrDobias #NMN #ProbioticSupport #EcoSupplements #FermentedVitamins

In this episode of the Tick Boot Camp Podcast, we sit down with Mark Ouellette, a retired law enforcement officer, professional bodybuilder, and former wrestler from the Boston, Massachusetts area. Mark shares his powerful story of overcoming chronic Lyme disease, including years of misdiagnoses, debilitating symptoms, and his battle to reclaim his health and identity.