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Victor Ambros, newly awarded the Nobel Prize for his discovery of microRNA, is a developmental biologist at the University of Massachusetts Medical School. In this episode, we explore improvisational science – the dynamic, collaborative process where researchers build on each other's ideas using a "yes, and…" approach. We discuss the constant need to reframe and refine scientific questions, and the challenge of helping young researchers build the confidence to question established ideas. Victor underscores the power of curiosity-driven research, emphasizing how each scientist's unique perspective can lead to discoveries others might miss. We also examine AI's evolving role in scientific discovery – particularly in synthesizing knowledge across disciplines – and how it can complement the cross-pollination of ideas at scientific conferences.For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .
Winners of the 2024 Nobel Prize in Physiology or Medicine Dr. Victor Ambros and Dr. Gary Ruvkun give a rare, extended joint interview about the road that led them to their discovery of miRNA in a roundworm, Dr. Ruvkun's later discovery of miRNA in humans, how the scientists were both inspired at a young age by astronomy, what Dr. Ambros' late father might have said about his son's Nobel win, and a decades-old story from Dr. Ruvkun about a trip to Bolivia.
Os MicroRNAs são pequenas moléculas de RNAs, que regulam a produção de proteínas das nossas células. Eles têm entre 17 e 25 nucleotídeos e reconhecem RNAs mensageiros-alvos, por meio da complementariedade entre as sequências. Se você quer entender um pouco mais sobre estes novos RNAs, que conquistaram o Prêmio Nobel de Fisiologia e Medicina em 2024, e saber o impacto que estas novas tecnologias terão na nossa vida, este episódio é para você. Então Vem Cienciar conosco!
V poslednej epizóde Rozhovory MD v tomto roku sme privítali vedkyňu a startupistku Janu Miniarikovú, ktorá nám priblížila svoju inšpiratívnu cestu od genetiky až po založenie vlastnej spoločnosti HypherData. Porozprávala nám o tom, čo ju motivovalo pri výbere genetiky ako odboru na Prírodovedeckej fakulte a pokračovaní štúdia v Holandsku. Tu získala titul PhD. vďaka výskumu microRNA v súkromnej spoločnosti, kde pracovala na vývoji génovej terapie na liečbu Huntingtonovej choroby. V epizóde sa dozviete prečo má väčšina lekárov v Holandsku titul PhD., koľko času venujú práci a prečo sú pre vedcov a vedkyne dôležité Nature publikácie. V druhej polovici epizódy sa pozrieme na to, čo Janu motivovalo pri uvažovaní o zmene kariéry, ako vznikol jej startup Hypherdata, akú úlohu zohráva zdieľanie dát medzi vedcami, nemocnicami a firmami. Diskutovali sme aj o tom, ako môže toto zdieľanie dát a nástup AI pomôcť pacientom s vážnymi ochoreniami, podporiť lekárov a lekárky v ich každodennej práci a aký potenciál majú pre formovanie novej podoby zdravotníctva. (01:30) Uvítanie (07:02) MicroRNA a Huntingtonova choroba (17:04) Ako sa dostať na štúdium PhD do Holandska (24:48) Open Science Movement (31:50) Ako bude AI pomáhať lekárom a lekárkam v blízkej budúcnosti (37:00) Krátke otázky na záver V januári organizujeme 90-minútový online masterclass na tému: ChatGPT pre lekárov a lekárky v praxi. Prihláste sa ak chcete ostať v obraze a zistiť ako: ušetriť čas s administratívou a nudnou komunikáciou vyhľadávať odborné informácie si pomôcť pri diagnostike lepšie edukovať pacientov a oveľa viac... Viac info a prihlásenie tu: https://lu.ma/s5wnlnkl Pre viac info o tom, čomu sa venuje HypherData, kliknite na tento odkaz: https://www.hypherdata.com/ Prajeme príjemné počúvanie!
The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA. It's too bad we at Reefer MEDness don't know anything about microRNA. But wait…We do! Hilal Kalkan, a post-doc at Laval University, talks to us about how microRNA and cannabinoid receptors are involved in the side effect of a common cholesterol medication. Come dive deep into the molecular workings of the endocannabinoid system with us!Hilal Kalkan - LinkedInDysfunctional endocannabinoid CB1 receptor expression and signaling contribute to skeletal muscle cell toxicity induced by simvastatin, Hilal Kalkan et al. - Paper in Cell Death and Disease(Yes we got a SOCAN membership to use this song all legal and proper like)Music by:Tuğba Yurt - Benim O -YouTubeAdditional Music:Desiree Dorion desireedorion.comMarc Clement - FacebookTranscripts, papers and so much more at: reefermed.ca
Letošní i loňské Nobelovy ceny odrážejí, jak zásadní je RNA pro naše zdraví. Prostřednictvím mRNA se přepisuje dědičná informace do bílkovin, microRNA ji kontroluje. Nejnovější výzkum vědců ze Švédska a Kanady je sledoval v prvních dnech vývoje lidského embrya.Všechny díly podcastu Laboratoř můžete pohodlně poslouchat v mobilní aplikaci mujRozhlas pro Android a iOS nebo na webu mujRozhlas.cz.
For the fifth time in its history, the Nobel Prize for Physiology or Medicine has been given for research into RNA. This year's Nobel Prize winners, Victor Ambros and Gary Ruvkun were awarded the prize for discovery of microRNA and its role in post-transcriptional gene regulation. What is microRNA? Why was its discovery important? What are the implications of this for research into human health and diseases? What is the current RNA research ongoing in India? And is RNA now taking centrestage for its importance in maintaining the balance in our cells, critical to good health and life? Guest: Reety Arora, a molecular biologist, with experience in stem cell biology, cancer research and CRISPR and currently principal scientist and head, R&D, CRISPRBITS, a company based in Bangalore. Host: Zubeda Hamid Edited by Jude Francis Weston
面膜團購日期: 2024/11/7-11/19 不定期會開補貨團喔! 加入團購群吧!很多好東西都在這裡
Broadcast from KSQD, Santa Cruz on 10-17-2024: Dr. Dawn addresses a listener's question about optimal timing for the consumption of iron, green tea, and nori powder to maximize absorption, recommending timing and supplementation strategies. She responds to a listener's email on the issue of plastic in tea bags and provides resources for finding plastic-free options, while also clarifying misconceptions about microplastics in seaweed and fish. Dr. Dawn celebrates the Nobel Prize in Physiology and Medicine awarded for the discovery of micro RNA, explaining its significance in gene regulation and potential therapeutic applications. She highlights a major neuroscience milestone: the mapping of a fruit fly's brain connectome, discussing its implications for understanding complex behaviors and neural circuits. Dr. Dawn provides comprehensive advice for managing ulcerative colitis, including vitamin D supplementation, CBD, omega-3 fatty acids, and stress reduction techniques. She discusses a study on pythons that could lead to new therapies for heart disease, explaining how the snake's unique cardiac adaptations might inform human treatments. Dr. Dawn introduces the Ronnie Gardner method, a music-based movement therapy showing promise in rehabilitation for stroke and Parkinson's disease patients.
Victor Ambros and Gary Ruvkun were awarded the 2024 Nobel prize in physiology or medicine for their discovery of microRNA, tiny biological molecules that tell the cells in our body what kind of cell to be by turning on and off certain genes.In this episode, we speak to Ambros, who is professor of natural sciences at UMass Chan Medical School in the US, about the discovery that led to his Nobel prize and find out what he's researching now. And we hear from Justin Stebbing, professor of biomedical sciences at Anglia Ruskin University in the UK, about how a deeper understanding of microRNA is opening up new avenues for potential treatment of diseases such as cancer. This episode was produced by Gemma Ware, Katie Flood and Mend Mariwany. Sound design was by Michelle Macklem and our theme music is by Neeta Sarl. Full credits for this episode are available. Sign up here for a free daily newsletter from The Conversation.If you like the show, please consider donating to The Conversation, which is an independent, not-for-profit news organisation. And please do rate and review the show wherever you listen.Further reading:MicroRNA − a new Nobel laureate describes the scientific process of discovering these tiny molecules that turn genes on and offMicroRNA is the Nobel-winning master regulator of the genome – researchers are learning to treat disease by harnessing how it controls genesNobel prize in medicine awarded for discovery of microRNAs, the molecules that control our genesFull coverage of the 2024 Nobel prizes on The Conversation Hosted on Acast. See acast.com/privacy for more information.
Ein und ein Viertel Jahrhundert werden die Nobelpreise nun schon vergeben. Dieses Jahr räumt ein super neues Forschungsgebiet zum ersten Mal ab. Und zwar grad doppelt. Wo Physik oder Chemie draufsteht ist nämlich ganz viel Künstliche Intelligenz drin. (00:00) Schlagzeilen (00:35) Eiweiss-Origami mit KI Die Proteinforschung der diesjährigen drei Chemienobelpreisträger wäre ohne KI nicht möglich gewesen. KI, die in den 1980er Jahren zum Sprung ansetzte und für deren Entwicklung zwei Forscher jetzt den Physiknobelpreis erhalten. John Hopfield und Geoffrey Hinton heissen die beiden Physiknobelpreisträger. Sie wollten verstehen, wie unser Gehirn denkt und brachten Maschinen das Lernen bei. Eine Sensation und gleichzeitig auch Grund für Besorgnis. Selbst für die KI-Pioniere selbst. (08:29) Als die Maschinen denken lernten Künstliche Gehirne beziehungsweise neuronale Netzwerke können viel. Unglaublich viel. Maschinelles Lernen auf der Basis künstlicher neuronaler Netzwerke gelingt heute bereits mit schmalster Kost. Mit minimalen Datenmengen gefüttert lernen Maschinen zu greifen wie eine menschliche Hand oder ausgestattet mit Schnurrhaaren und Rädern wie eine Ratte unbekannte Räume zu erkunden und vieles, vieles mehr. (15:07) MicroRNA leistet mega Grosses In unserem Körper reguliert microRNA die Aktivität von Genen. Sie bremst oder feuert Gene an und sagt den Zellen, wer sie sind: eine Muskelzelle, eine Leberzelle, eine Hirnzelle... MicroRNA ist auch beteiligt an der Entstehung von Krankheiten wie Krebs. Und darin liegt auch eine Chance. Die Wissenschaftler, die dieses Jahr den Medizin-Nobelpreis erhalten, legten mit ihrer Forschung auch den Grundstein für mögliche neue Medikamente. (21:41) Wie gewinnt man einen Nobelpreis Indem man dazugehört. Männlich und weiss zu sein ist eine gute Voraussetzung. Zur richtigen Zeit am richtigen Ort die richtigen Leute zu kennen ebenfalls. Wer in einem Labor eines Wissenschaftlers arbeitet, der bereits einen Nobelpreis erhalten hat, erhöht seine eigenen Gewinnchancen. Ein einziges grosse Netzwerk stellt die meisten Gewinner. Nur ganz vereinzelt kommen Aussenseiterinnen und Aussenseiter an die Pötte. Mehr zum Wissenschaftsmagazin und Links zu Studien: https://www.srf.ch/wissenschaftsmagazin .
A Nobel prize for understanding how genes are turned on and offThe early-morning call from Sweden came on Monday to American molecular biologist Gary Ruvkun for his work in discovering microRNAs, which are essential for regulating genetic activity in plants and animals. Ruvkun says that research based on this work helps us understand basic biology, but has also provided significant insight into disease and might even help us understand whether there is life on other planets. Biologists discover a new microbial world in your bathroomResearchers have found a new biodiversity hotspot. Environmental microbiologist Erica Hartmann and her team sampled showerheads and toothbrushes in ordinary bathrooms, and found a host of bacteria and hundreds of previously unknown viruses. But don't panic: much of this new life are bacteriophages — viruses that infect bacteria — which are harmless to humans and could be potential weapons against the bacteria that can cause human disease. The study was published in the journal Frontiers in Microbiomes.How we might zap an asteroid on a collision course with EarthA new experiment using the world's most powerful radiation source has shown the way to deflecting asteroids with X-rays. The X-rays were used to vaporize some of the surface of a model asteroid, creating a rocket-like effect. Dr Nathan Moore, a physicist at the Sandia National Laboratories in New Mexico, says it's a proof of principle for the concept of deflecting a real asteroid using X-rays generated by a powerful nuclear explosion. The study was published in the journal Nature Physics. Exploring the origins of Australia's iconic, if controversial, wild dogThe Australian Dingo has a fierce reputation as a predator, leading to European settlers attempting to exterminate it in the 19th century. But the dingo's origin story has not been well understood. For years, it was assumed the dingo originated from India, given its similarities to the Indian pariah dog, or from New Guinea. Dr. Loukas Koungolos, a research associate at the University of Sydney, led the study looking at dingo fossils and found out where it likely came from, and how the domestic dogs of ancient people became a wild predator down under. The study was published in the journal Scientific Reports. Can we treat autoimmune disease by manipulating the immune system? Autoimmune diseases like Lupus can be a result of critical immune cells attacking our own bodies. New advances are pointing to ways we might be able to reverse this. Researchers have repurposed a relatively new cancer treatment, called CAR-T therapy that can reprogram immune cells to attack cancer cells, to reset the immune system in patients with lupus to neutralize its autoimmune attack. Dr. Georg Schett and his colleagues, from the Friedrich Alexander University of Erlangen in Germany, were the first to use this immunotherapy to successfully treat lupus patients. That research appeared in the journal Nature Medicine with a follow-up in The New England Journal of Medicine.Other researchers are focussing on understanding — and possibly reversing — what triggers the immune cells to go awry in the first place. Dr. Jaehyuk Choi, from Northwestern University, said they found a molecule that lupus patients are deficient in. In cell culture they demonstrated that correcting this deficiency can reprogram certain immune T-cells to stop directing the attack on the body which they hope could potentially reverse the effects of lupus. His research was published in Nature.
I sistemi di intelligenza artificiale sono stati al centro dei premi Nobel scientifici assegnati questa settimana. Il Nobel per la Fisica è stato assegnato a John J. Hopfield e Geoffrey E. Hinton per i loro studi nello sviluppo di sistemi di apprendimento automatico, alla base della rapida evoluzione delle AI degli ultimi anni. Le loro ricerche sono partire dalla fisica, ma l'hanno presto abbandonata per addentrarsi in elaborate soluzioni informatiche, di conseguenza i puristi si sono un po' risentiti per un Nobel che ritengono abbia poco a che fare con la Fisica. È successo qualcosa di simile con il Nobel per la Chimica che ha premiato tre ricercatori che hanno innovato profondamente il campo dello studio delle proteine, sempre con sistemi di intelligenza artificiale. Il Nobel per la Medicina è stato invece assegnato agli autori della scoperta del microRNA, fondamentale per regolare lo sviluppo delle funzioni delle cellule. Vediamo perché le scoperte premiate quest'anno possono cambiarci la vita e, anzi, hanno già iniziato a farlo. Leggi anche: – È iniziato il viaggio di Hera verso gli asteroidi – Il Nobel per la Medicina a Victor Ambros e Gary Ruvkun per la scoperta del microRNA – Il Nobel per la Fisica a John J. Hopfield e Geoffrey E. Hinton per i loro studi sulle intelligenze artificiali – Bisogna capirsi su cosa sia “l'intelligenza artificiale” – Il Premio Nobel per la Chimica a David Baker, Demis Hassabis e John M. Jumper per i loro studi sulle proteine – Oppenheimer e il dilemma dell'atomica Learn more about your ad choices. Visit megaphone.fm/adchoices
With awards for the discovery of microRNA and the creation of new proteins, plus recognition for artificial intelligence via the physics and chemistry prizes, Madeleine Finlay hears from the Guardian science team – Nicola Davis, Ian Sample and Hannah Devlin – as they break down the news, science and surprises from this year's Nobels. Help support our independent journalism at theguardian.com/sciencepod
La medicina del futuro: microRNA gana Premio Nobel de Medicina: explica Israel PichardoEnlace para apoyar vía Patreon:https://www.patreon.com/julioastilleroEnlace para hacer donaciones vía PayPal:https://www.paypal.me/julioastilleroCuenta para hacer transferencias a cuenta BBVA a nombre de Julio Hernández López: 1539408017CLABE: 012 320 01539408017 2Tienda:https://julioastillerotienda.com/ Te invitamos a que visites nuestro perfil en Patreon. Solo da clic aquí Hosted on Acast. See acast.com/privacy for more information.
化学奖给了AI,物理学奖给了AI,医学和生理学奖嘛......没人关心了
今天诺贝尔医学奖颁奖,两位美国科学家因为发现MicroRNA和它们的调节机制获奖。而他们的导师均是诺奖得主,不难看出“名师出高徒”,师从天才,或许是个硬道理。
On today's podcast, a theater exchange between Japan and Britain brings cultural knowledge; two Americans win the Nobel prize for microRNA discovery; U.S. severe obesity is rising followed by a discussion of ‘prevalent;' then, superlatives on Lesson of the Day.
Morse code transcription: vvv vvv Gary Lineker says BBC contract talks over Match of the Day have just started Mexican mayor murdered days after starting job Nobel Prize goes to microRNA researchers Chris Mason Why it was always likely Sue Gray would go Food rating lies exposed by BBC secret recording Madonna pays tribute to brother Christopher Ciccone House prices close to record high, says Halifax Oasis on the Adriatic where Ukrainians and Russians have gone to escape war Cardiff Half Marathon Runner dies after 2024 race How perfect storm blew away planned social homes England needs
United States correspondent Todd Todd Zwillich spoke to Lisa Owen about two American biologists being awarded the Nobel Prize in medicine for their work on the discovery of microRNA, and explains what microRNA is.
*) UN rights office calls for end to Israel's impunity over Gaza atrocities As Israel's war on Gaza marks a year, the UN warns of widespread violations of international law. Nearly 42,000 have died, and Gaza faces severe displacement, hunger, and disease. The UN stresses accountability is vital to end impunity and the cycle of conflict as Israeli attacks on civilians, schools, and hospitals continue, fueling violence. *) Israel to expand its offensive to south Lebanon coast The Israeli army plans to expand its operations against Hezbollah along Lebanon's coast south of the Awali river. Army spokesperson Avichay Adraee warned civilians to avoid the shore, citing imminent maritime actions. In Israel's northwest, four areas have been declared "closed military zones," restricting access amid heightened tensions on the Lebanon border. *) A year on, Netanyahu has failed families of Israeli hostages Families of hostages held by Hamas gathered near Prime Minister Netanyahu's residence, accusing him of stalling efforts to secure their loved ones' release. About 100 hostages remain in Gaza, many are feared dead. Emotions ran high as families demanded action, with one mother saying, "We won't let you rest until all of them are back." During the gathering, Israel confirmed another hostage's death. *) Shocking surge in Islamophobia as anti-Muslim hatred skyrockets in UK Anti-Muslim hatred in the UK has surged, with Tell MAMA recording 4,971 incidents between October 2023 and September 2024. The NGO's report highlights the rise of verbal abuse, threats and violence, particularly targeting visibly Muslim individuals. Major urban centres, including London, saw the most cases. The group calls for urgent action to curb this growing hostility. *) US researchers win Nobel for cracking gene regulation US scientists Victor Ambros and Gary Ruvkun won the Nobel Prize in Medicine for discovering microRNA, a breakthrough in gene regulation. The Nobel Assembly calls it “a completely new principle” essential for life. The duo celebrated virtually, with Ruvkun excitedly preparing for December's Nobel gala. Their work has significant implications for understanding cell physiology and diseases like cancer.
Hai nhà khoa học Mỹ đã giành giải Nobel về sinh lý học hoặc y học vì phát hiện ra microRNA, những đoạn nhỏ của vật liệu di truyền cung cấp một cách thức, để các nhà khoa học kiểm soát những gì đang xảy ra trong tế bào của chúng ta. Phát hiện của họ có thể dẫn đến những cách mới, để tìm ra và điều trị các bệnh, bao gồm cả ung thư.
Victor Ambros and Gary Rukvun discovered microRNA -- molecules that control how genes regulate each other inside cells. The discovery is the basis for some disease treatments.
Matthias Miersch soll neuer SPD Generalsekretär werden / Zahl der Rentner die in Deutschland auf Sozialhilfe angewiesen sind auf Höchststand / Älteste bekannter Baum Österreichs vor vermeintlichem Lebensende / ESA-Sonde "Hera" soll Asteroiden erreichen und untersuchen / Laut Flüchtlingsagentur der Vereinten Nationen kehren vertriebene Syrer*innen nach Syrien zurück / Australische Regierung sieht sich neuer rechtlichen Herausforderung bei Einwanderungshaftsystem gegenüber / Regierung von New South Wales will bis 2035 jährlich 91 Milliarden Dollar durch Tourismus generieren / Gipfel gegen Verlust der Biodiversität und Zusammenbruch von Ökosystemen im Sydney / Zwei Wissenschaftler gewinnen Medizin-Nobelpreis für Entdeckung von microRNA
microRNA: zwei US-amerikanische Forscher haben sie zufällig entdeckt - in einem unscheinbaren Fadenwurm. Sie regulieren unsere Gene, bestimmen mit, ob wir krank werden oder gesund bleiben: Jetzt werden Victor Ambros und Gary Ruvkun für die Entdeckung mit dem Medizin-Nobelpreis 2024 ausgezeichnet, denn das Verständnis der Moleküle ermöglicht ganz neue Therapien. In dieser Podcast Folge fragen wir: was sind microRNAs, was können sie? Und wie können wir sie nutzen, um Krankheiten wie Krebs, Diabetes oder Herzschwäche zu bekämpfen?
Israel launches new ground operations across Gaza one year from the Oct. 7 attacks, Harris talks family and abortion on 'Call Her Daddy', Trump returns to Butler for a campaign rally, Sue Gray resigns as Keir Starmer's chief of staff, a blast in Karachi kills two Chinese nationals, Tunisian Pres. Kais Saied is expected to win reelection, SCOTUS declines to hear Biden's appeal in a Texas abortion case, a report shows that 2023 was the driest year for rivers in three decades, Florida braces for another hurricane, Lebron and Bronny James make NBA history, and two US scientists win the Nobel Prize for their discovery of microRNA. Sources: https://www.verity.news/
Morse code transcription: vvv vvv Food rating lies exposed by BBC secret recording Oasis on the Adriatic where Ukrainians and Russians have gone to escape war How perfect storm blew away planned social homes England needs Mexican mayor murdered days after starting job Cardiff Half Marathon Runner dies after 2024 race House prices close to record high, says Halifax Chris Mason Why it was always likely Sue Gray would go Madonna pays tribute to brother Christopher Ciccone Nobel Prize goes to microRNA researchers Gary Lineker says BBC contract talks over Match of the Day have just started
Morse code transcription: vvv vvv Gary Lineker says BBC contract talks over Match of the Day have just started Mexican mayor murdered days after starting job House prices close to record high, says Halifax Nobel Prize goes to microRNA researchers Madonna pays tribute to brother Christopher Ciccone Oasis on the Adriatic where Ukrainians and Russians have gone to escape war How perfect storm blew away planned social homes England needs Cardiff Half Marathon Runner dies after 2024 race Food rating lies exposed by BBC secret recording Chris Mason Why it was always likely Sue Gray would go
Pyramid of Cestius https://en.wikipedia.org/wiki/Pyramid_of_Cestius (via ChatGPT) resumo de Raízes do Brasil https://chatgpt.com/share/6704f90d-e8b4-8006-aa61-5773bc08968e (via Gemini) Singapore's History in Brief https://g.co/gemini/share/cc0dbdf003e2 (via Gemini) Escala da Lava Jato https://g.co/gemini/share/b0b415b84390 Raízes do Brasil https://a.co/d/eBBSJ3v Conheça ‘Raízes do Brasil', o livro que sempre cai nos vestibulares https://guiadoestudante.abril.com.br/estudo/conheca-raizes-do-brasil-o-livro-que-sempre-cai-nos-vestibulares MicroRNA is the Nobel-winning master regulator of the genome – researchers are learning ... Read more The post ChatGPT é alienígena? como explicar o Brasil para um estrangeiro? appeared first on radinho de pilha.
Good afternoon, I'm _____ with today's episode of EZ News. Tai-Ex opening The Tai-Ex opened marginally (略微地) down this morning from yesterday's close, at 22,691 on turnover of 5-billion N-T. The market rebounded from Friday's downturn on Monday - gaining almost 400 points on the back of a rally by Taiwan Semiconductor Manufacturing. Analysts say market sentiment improved as investors reacted to gains on Wall Street at the end of last week - where better-than-expected nonfarm payroll data for September indicated that the U-S economy remains resilient. Environmental Groups Pan Recommended Carbon Fee Environmental groups are criticizing the basic carbon fee and preferential rates proposed by the government - calling them "passive" and too low to affect the behavior of big carbon emitters. The criticisim comes after a review committee recommended setting a basic carbon fee rate of 300 N-T per metric ton of carbon emissions. The groups says the basic carbon fees are too low to effectively reduce carbon emissions and companies could see them as an affordable (付得起的) operating expense or pass them on to consumers rather than invest resources to reduce emissions and the fees. Ariel Lin Wins best Leading Actress at Asian Film Award Actress Ariel Lin has won the award for Best Lead Female Actor at the 2024 Asia Contents Awards & Global OTT Awards in South Korea. Lin won the award for her performance in the Taiwanese television drama "Imperfect Us." She received the award in-person at the ceremony in Busan - where she gave a teary (熱淚盈眶) speech in Korean, saying that the award was "a great motivation for both me and the work." The Asia Contents Awards & Global OTT Awards is now in its sixth year. It's organized jointly by the Busan International Film Festival and South Korea's National I-T Industry Promotion Agency. NKorea Kim Issues Warning for Nuclear Weapons North Korea says leader Kim Jong Un has warned again that he could use nuclear weapons in potential conflicts with South Korea and the United States. State media today said Kim made such a warning in his speech at a university. Kim said North Korea's nuclear response posture must be fully enhanced because South Korea and the United States are pushing to beef up their military alliance based on joint nuclear and strategic planning, a move that he said would increase (增加) the danger of breaking the balance of power on the Korean Peninsula. Kim has issued similar threats to use nuclear weapons preemptively numerous times, but his latest warning came as outside experts say North Korea could ramp up animosities ahead of next month's U.S. presidential election. US Scientists Win Nobel for microMRNA Discovery American scientists Victor Ambros and Gary Ruvkun have won this year's Nobel Prize in physiology (生理)or medicine for the discovery of microRNA, a tiny molecule that governs how cells in the body function. It has been connected to heart disease, cancers and viral diseases. Kate fisher reports That was the I.C.R.T. EZ News, I'm _____.
Morse code transcription: vvv vvv Madonna pays tribute to brother Christopher Ciccone How perfect storm blew away planned social homes England needs Cardiff Half Marathon Runner dies after 2024 race Gary Lineker says BBC contract talks over Match of the Day have just started Food rating lies exposed by BBC secret recording Mexican mayor murdered days after starting job House prices close to record high, says Halifax Chris Mason Why it was always likely Sue Gray would go Oasis on the Adriatic where Ukrainians and Russians have gone to escape war Nobel Prize goes to microRNA researchers
No podcast ‘Notícia No Seu Tempo', confira em áudio as principais notícias da edição impressa do jornal ‘O Estado de S.Paulo' desta terça-feira (08/10/2024): Ricardo Nunes (MDB) e Guilherme Boulos (PSOL) indicaram o rumo da fase final da campanha horas após a confirmação de que a eleição em SP será definida em segundo turno. O atual prefeito vai investir na captura de votos das candidaturas derrotadas. Ele acredita que o eleitorado de Pablo Marçal (PRTB) migrará majoritariamente para sua candidatura. Boulos vai insistir num discurso crítico à atual gestão e no que avalia ser um desejo de mudança dos moradores da cidade, além de tentar recuperar terreno entre os eleitores da periferia. No primeiro turno, Nunes superou Boulos por uma margem estreita de votos. O emedebista obteve 29,48% dos votos válidos, ante 29,07% do candidato do PSOL. E mais: Política: Tarcísio vai bem em seu primeiro teste como cabo eleitoral e ganha independência Internacional: Israel faz homenagem às vítimas do Hamas e envia mais tropas ao Líbano Metrópole: Dupla descobridora do microRNA leva o Nobel de Medicina See omnystudio.com/listener for privacy information.
Plus: New York City's deputy mayor is the latest aide to Mayor Eric Adams, who has been indicted on corruption charges, to resign. The Nobel Prize for Medicine is awarded to a pair of scientists for their discovery of microRNA, tiny molecules that play an important role in gene regulation. J.R. Whalen reports. Sign up for the WSJ's free What's News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices
“I heard what sounded like an authentic call from the Nobel Committee!” New medicine laureate Gary Ruvkun might have received a prank call or two in the past, but today's was genuine. He talked to the Nobel Prize's Adam Smith minutes after hearing the news, about the pleasure of finding things out, the electrifying growth of the microRNA field over the years, and the benefits of taking time out. And as for what's about to follow: “It's going to be a fun ride!” Hosted on Acast. See acast.com/privacy for more information.
Mit der Beschreibung der kleinen RNA-Moleküle haben die Preisträger Victor Ambros und Gary Ruvkun einen Prozess der Genregulation erklärt. MicroRNAs steuern die Produktion von Proteinen und sind damit entscheidend für die Entwicklung eines Organismus. Von Anneke Meyer
Krauter, Ralf www.deutschlandfunk.de, Forschung aktuell
Lange, Michael www.deutschlandfunk.de, Forschung aktuell
Two Americans have been awarded the Nobel prize for medicine. AP correspondent Jennifer King reports.
Jahrestag des Terrorangriffs der Hamas auf Israel, SPD-Generalsekretär Kevin Kühnert tritt aus gesundheitlichen Gründen zurück, Matthias Miersch wird neuer Generalsekretär der SPD, Medienbericht warnt vor Zahlungsunfähigkeit der Pflegeversicherung, Nobelpreis für Medizin geht an zwei US-Gen-Forscher für Entdeckung der "microRNA", Europäische Raumfahrtorganisation ESA schickt Sonde "Hera" zur Erforschung von Schutz vor Asteroiden-Einschlägen ins All, Das Wetter
Victor Ambros and Gary Ruvkun have discovered microRNA and its role in post-transcriptional gene regulation, revealing an entirely new dimension to gene regulation.
(1) Verrassingsaanval Hamas 7 oktober '23 toch niet zo'n verrassing (2) Lia van Bekhoven las memoires Boris Johnson (3) 1 op 7 studenten doet aan zelfverminking (4) Nobelprijs Geneeskunde naar ontdekking MicroRNA (5) Middagjournaal van Stella Bergsma
- Lễ đón Tổng Bí thư, Chủ tịch nước Tô Lâm thăm chính thức Cộng hòa Pháp được tổ chức trọng thể theo nghi thức quốc gia tại Điện Invalides ở thủ đô Paris- Chủ trì Phiên họp Chính phủ trực tuyến với 63 địa phương và Phiên họp thường kỳ Chính phủ tháng 9, Thủ tướng Phạm Minh Chính chỉ rõ 5 nhóm nhiệm vụ, giải pháp quan trọng thời gian tới, phấn đấu tăng trưởng GDP năm nay trên 7%- Ủy ban Thường vụ Quốc hội rà soát, chuẩn bị các nội dung cho Kỳ họp thứ 8, Quốc hội khóa XV khai mạc vào ngày 21 tháng này- Trung Quốc ngừng mua vàng dự trữ tháng thứ năm liên tiếp. Trong khi đó, dự trữ ngoại hối của nước này lần đầu tiên trở lại mốc 3.300 tỷ USD sau 9 năm- Giải Nobel Y sinh năm nay vinh danh 2 nhà khoa học người Mỹ với phát hiện ra microRNA, một loại phân tử RNA nhỏ mới, có vai trò quan trọng trong quá trình điều hòa gen Chủ đề : tổng bí thư, chủ tịch nước, thăm pháp --- Support this podcast: https://podcasters.spotify.com/pod/show/vov1thoisu0/support
Guest: David Henshall - Professor of Physiology and Medical Physics at RCSI and author of Fine-Tuning Life: A Guide to MicroRNAs, Your Genome's Master Regulators.
BUFFALO, NY- August 5, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 12, 2024, entitled, “INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death.” In this study, researchers Chantal L. Duurland, Thijs de Gunst, Harm C. den Boer, Marion T.J. van den Bosch, Bryony J. Telford, Rogier M. Vos, Xiaolei Xie, Mingfa Zang, Fang Wang, Yingying Shao, Xiaoyu An, Jingjing Wang, Jie Cai, Ludovic Bourré, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot, and Sanaz Yahyanejad from InteRNA Technologies BV, Utrecht, The Netherlands, and Crown Bioscience Inc., in San Diego, examined the effect of their lipid nanoparticle (LNP) formulated, chemically modified, synthetic miR-193a-3p mimic (INT-1B3) on anti-tumor immunity. “In this study, we examined the effect of our lipid nanoparticle (LNP) formulated, chemically modified, synthetic miR-193a-3p mimic (INT-1B3) on animal survival, tumor microenvironment (TME) and induction of anti-tumor immune responses.” The data presented within the study demonstrates for the first time that miR-193a-3p induces long-term immunity against tumor development via modulation of the tumor microenvironment and induction of immunogenic cell death. Additionally, the data show that systemic administration of INT-1B3 to 4T1 and H22 tumor bearing immunocompetent mice prolonged animal survival by reducing metastasis compared to phosphate buffered saline (PBS) or anti-programmed death (PD) 1 treatment. DOI - https://doi.org/10.18632/oncotarget.28608 Correspondence to - Sanaz Yahyanejad - sanaz.yah@gmail.com Video short - https://www.youtube.com/watch?v=pK_Bs5vMBCQ Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28608 Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/ Keywords - cancer, miR-193a-3p, microRNA mimic, T cell mediated immunity, immunogenic cell death About Oncotarget Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking different fields of oncology, cancer research and biomedical sciences; and foster application of basic and clinical science. Oncotarget is indexed and archived by PubMed/Medline, PubMed Central, Scopus, EMBASE, META (Chan Zuckerberg Initiative) (2018-2022), and Dimensions (Digital Science). To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us: Facebook - https://www.facebook.com/Oncotarget/ X - https://twitter.com/oncotarget Instagram - https://www.instagram.com/oncotargetjrnl/ YouTube - https://www.youtube.com/@OncotargetJournal LinkedIn - https://www.linkedin.com/company/oncotarget Pinterest - https://www.pinterest.com/oncotarget/ Reddit - https://www.reddit.com/user/Oncotarget/ Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh MEDIA@IMPACTJOURNALS.COM
Andrew Yoo, Ph.D., provides insight into the ongoing research on neurodegeneration and neuronal reprogramming, highlighting the complexities and challenges in modeling and understanding these processes. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39454]
Early identification of diseases in animals is critical to the future of the food system, national security and our ability to care for our pets. One company is harnessing the power of biology to accelerate identification and joined us from the Agbioscience Podcast Corner at the Animal Health, Nutrition, Innovation and Technology Conference in Boston. Eve Hanks, founder and CEO of MI:RNA Diagnostics, joins us to talk their biomarker platform reliant on microRNA that has the potential to transform the future of animal health. Eve gets into how the platform works and success her team has experienced since spinning out of Scotland's Rural College. She also talks the importance of partnerships to drive innovation forward. With diseases like Avian Flu and African Swine Fever threatening the global food system, how can a tool like MI:RNA help? Eve talks combatting disease in animals and how an increased awareness of microRNA is driving interest in her team's work.
Early identification of diseases in animals is critical to the future of the food system, national security and our ability to care for our pets. One company is harnessing the power of biology to accelerate identification and joined us from the Agbioscience Podcast Corner at the Animal Health, Nutrition, Innovation and Technology Conference in Boston. Eve Hanks, founder and CEO of MI:RNA Diagnostics, joins us to talk their biomarker platform reliant on microRNA that has the potential to transform the future of animal health. Eve gets into how the platform works and success her team has experienced since spinning out of Scotland's Rural College. She also talks the importance of partnerships to drive innovation forward. With diseases like Avian Flu and African Swine Fever threatening the global food system, how can a tool like MI:RNA help? Eve talks combatting disease in animals and how an increased awareness of microRNA is driving interest in her team's work.
https://passionstruck.com/passion-struck-book/—Order a copy of my new book, "Passion Struck: Twelve Powerful Principles to Unlock Your Purpose and Ignite Your Most Intentional Life," today! The book was picked by the Next Big Idea Club as a must-read for 2024, the winner of the Business Business Minds Best Book 2024, and a finalist for the Eric Hoffer First Horizon Award for best debut novel.In this episode of Passion Struck, host John R. Miles interviews Dr. Michael Greger, a renowned physician and author who shares valuable insights on preventing diseases, improving health, and promoting longevity through lifestyle interventions. The episode covers a wide range of topics, including the impact of diet on heart disease, strategies for preserving bone health, tips for maintaining cognitive function and enhancing sexual health. Full show notes and resources can be found here: https://passionstruck.com/dr-michael-greger-on-blueprint-for-healthy-aging/In this episode, you will learn:The importance of lifestyle interventions and promoting health and longevity based on his personal experience with his grandmother's recovery from heart disease.The impact of nutrition on preventing diseases like heart disease and cancer.Insights on the Mediterranean and Okinawan diets, emphasizing the benefits of whole plant foods for overall health.Strategies for preserving bone strength, cognitive health, and sexual function as part of an anti-aging approach.Xenohormesis and microRNA manipulation as potential mechanisms for improving health and longevity through plant-based diets and exercise.All things Dr. Michael Greger: https://nutritionfacts.org/SponsorsBrought to you by Indeed. Head to https://www.indeed.com/passionstruck, where you can receive a $75 credit to attract, interview, and hire in one place.Brought to you by Nom Nom: Go Right Now for 50% off your no-risk two week trial at https://trynom.com/passionstruck.Brought to you by Cozy Earth. Cozy Earth provided an exclusive offer for my listeners. 35% off site-wide when you use the code “PASSIONSTRUCK” at https://cozyearth.com/This episode is brought to you by BetterHelp. Give online therapy a try at https://www.betterhelp.com/PASSIONSTRUCK, and get on your way to being your best self.This episode is brought to you By Constant Contact: Helping the Small Stand Tall. Just go to Constant Contact dot com right now. So get going, and start GROWING your business today with a free trial at Constant Contact dot com.--► For information about advertisers and promo codes, go to:https://passionstruck.com/deals/Catch More of Passion StruckWatch my interview with Dr. Lucia Aronica On The Impact Of Personalized Nutrition On EpigeneticsMy solo episode on how to heal from the consequences of abuseCan't miss my episode with Dr. Will Cole On How To Restore Your Gut-Feelings ConnectionListen to my interview with Dr. Kara Fitzgerald On How To Become A Younger You By Reversing Your Biological AgeMy solo episode on The Science Of Healthy HabitsCheck Out my episode with Dr. Mark Hyman On The Secrets To Living Young ForeverLike this show? Please leave us a review here-- even one sentence helps! Consider including your Twitter or Instagram handle so we can thank you personally!How to Connect with JohnConnect with John on Twitter at @John_RMiles and on Instagram at @john_R_Miles.Subscribe to our main YouTube Channel Here: https://www.youtube.com/c/JohnRMilesSubscribe to our YouTube Clips Channel: https://www.youtube.com/@passionstruckclips