Podcasts about tsien

Joe talks about the life & mind of Roger Tsien, Livingston's only Nobel Prize winner; Jessica tells us about the hottest new books hitting our shelves in August; Hongmei plays a clip of a powerful performance from this year's Olympics.

We have Amy Tsien with us on the Unlabelling Effect in this episode! Amy is an avid advocate for physical and mental well-being, which has led her to become the founder of Eve Bliss, a functional wellness brand that produces research-backed revitalising functional products, raises awareness for mental health initiatives, and runs community events. The horrid experience of being bullied at school, Amy was forced to look inward and live her authentic life in order to regain control in life. In her opinion, wellness should be inclusive and for EVERYONE. Tune in to hear her journey and ways to take care of your physical and mental health. Sponsors:Thank you, The Blomstre Candles and Eve Bliss, for the sponsored products .-5% off for all Eve Bliss products and events with the discount code “UEXEVEBLISS” -10% discount with a minimum purchase of $300 on their website theblomstre.com.with the discount code “UEFFECT” If you are new to our podcast, the Unlabelling Effect, our very warm welcome! We are Melody, Rita and Vivian, three distinctive women daringly diving into some taboos with the intention of normalise some uncomfortable yet vital conversations. By disrupting the fear of opening up about one‘s vulnerability and insecurities, we hope to develop a self-empowering and growing mindset collectively

The island of Kinmen is a small island with a potentially big problem. Situated just off the coast of China, but part of Taiwan, Kinmen would likely be the first line of defense should the Chinese government decide to invade Taiwan. Emmy-nominated director S. Leo Chiang, who was born in Taiwan, worked in China and also lived for years in the U.S., explores the complex relationship between place, identity and politics in his insightful and masterfully crafted documentary short “Island in Between”.   Joining Ken on the pod, Leo and producer Jean Tsien delve into the backstory of Kinmen — a flashpoint between Taiwan, China and the U.S. going back to the Chinese Civil War —and its present day role as a tourist spot, military base and home to thousands of people who live betwixt and between. Leo and Jean also illuminate how their personal backstories of growing up in Taiwan informed the making of the film and what makes their creative partnership so special.   “Island in Between” has been nominated for the Oscar for Best Documentary Short. It can be streamed on The New York Times Op-Docs site.   The Presenting Sponsor of "Top Docs" is Netflix.   Follow: @SLeoChiang on Instagram and twitter @topdocspod on Instagram and twitter

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.27.538511v1?rss=1 Authors: Chamberland, S., Grant, G., Machold, R. P., Nebet, E. R., Tian, G., Hanani, M., Kullander, K., Tsien, R. W. Abstract: Hippocampal somatostatin-expressing (Sst) GABAergic interneurons (INs) exhibit considerable anatomical and functional heterogeneity. Recent single cell transcriptome analyses have provided a comprehensive Sst-IN subtype census, a plausible molecular ground truth of neuronal identity whose links to specific functionality remain incomplete. Here, we designed an approach to identify and access subpopulations of Sst-INs based on transcriptomic features. Four mouse models based on single or combinatorial Cre- and Flp- expression differentiated functionally distinct subpopulations of CA1 hippocampal Sst-INs that largely tiled the morpho-functional parameter space of the Sst-INs superfamily. Notably, the Sst;;Tac1 intersection revealed a population of bistratified INs that preferentially synapsed onto fast-spiking interneurons (FS-INs) and were both necessary and sufficient to interrupt their firing. In contrast, the Ndnf;;Nkx2-1 intersection identified a population of oriens lacunosum-moleculare (OLM) INs that predominantly targeted CA1 pyramidal neurons, avoiding FS-INs. Overall, our results provide a framework to translate neuronal transcriptomic identity into discrete functional subtypes that capture the diverse specializations of hippocampal Sst-INs. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.09.536164v1?rss=1 Authors: Lev-Ram, V., Palida, S., Deerinck, T. J., Bushong, E. A., Toyoma, B. H., Perez, A., McClatchy, D. B., Prichard, D. R., Savas, J. N., Ellisman, M. H., Yates, J. R., Tsien, R. Y. Abstract: Perineuronal nets (PNN), a specialized form of ECM, surround numerous neurons in the CNS and allow synaptic connectivity through holes in its structure. We hypothesize that PNNs serve as gatekeepers that guard and protect synaptic territory and thus may stabilize an engram circuit. We present high-resolution and 3D EM images of PNN-engulfed neurons showing that synapses occupy the PNN holes and that invasion of other cellular components is rare. PNN constituents are long-lived and can be eroded faster in an enriched environment, while synaptic proteins have a high turnover rate. Preventing PNN erosion using pharmacological inhibition of PNN-modifying proteases or MMP9 knockout mice allowed normal fear memory acquisition but diminished remote-memory stabilization, supporting the above hypothesis. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

After WWII, the U.S. hired and promoted Nazi aerospace engineers in a program called Operation Paperclip — yet it drove away its own rocketeers, Malina and Tsien, for alleged communist activity. In this episode, we unpack that paradox.    This episode is sponsored by BetterHelp. Save 10% off your first month at BetterHelp.com/ROCKETS

While Frank Malina escaped the worst of the FBI's treatment, Suicide Squad member Tsien Hsue-Shen was not so lucky. This episode chronicles the shocking story of how the United States wound up losing one of its most brilliant minds in rocketry to China.    This episode is sponsored by BetterHelp. Save 10% off your first month at BetterHelp.com/ROCKETS

Monique Tjon A Tsien is huisarts en heeft haar eigen praktijk. Daarnaast is ze gespecialiseerd in hart-en vaatziekten en is Integrale Leefstijl arts. Maar Monique doet meer, veel meer. Haar bijnaam is niet voor niets  ‘de ijsdokter'.  Ze faciliteert koude training en ademwerk via Koude seminar en adem pro.Waarom kou en ademwerk goed voor je is en wat het je oplevert gaan we o.a. in deze podcast bespreken.We hebben het over haar missie en de onderliggende reden. Celgeheugen, DNA en onze eigen chemische fabriek.Het eerste deel van de podcast legt ze uit welke voordelen kou en ademhaling hebben. Naarmate de podcast vordert gaan we de diepte in.Daar hebben we het over leefstijl, routine en discipline. Waarom het belangrijk is dat we het anders gaan doen dan hoe we het nu doen.Uiteindelijk komen we aan het einde van het gesprek uit op de essentie. We zijn allemaal licht en liefde.Een mooi gesprek met iemand die leeft wat ze voorschrijft. Als het moet zijn dat pillen maar als ze de mogelijkheid heeft het anders op te lossen zal ze die kans niet laten liggen.Ik hoop dat je deze podcast kan waarderen. Als dat zo is geef dan een duimpje of een aantal sterren, dankjewel en veel luisterplezier!Roald Ploegmakers#gamechangers #bewusteleiders #podcast #ijsdokter #kou #adem #winterzwemmen #moniqueTjonATsien #integraleleefstijlarts

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.12.14.519639v1?rss=1 Authors: Osakada, T., Yan, R., Jiang, Y., Wei, D., Tabuchi, R., Dai, B., Wang, X., Zhao, G., Wang, C. X., Tsien, R. W., Mar, A. C., Lin, D. Abstract: To survive and thrive in a complex social group, it is essential to not only know who to approach but more importantly who to avoid. After a single defeat, mice learn to stay away from the winning aggressor for weeks. Here, we identify oxytocin neurons in the retrochiasmatic supraoptic nucleus (SOROXT) and oxytocin receptor expressing cells in the anterior subdivision of ventromedial hypothalamus, ventrolateral part (aVMHvlOXTR) as a key circuit motif for defeat-induced social avoidance learning. After defeat, aVMHvlOXTR cells drastically increase their responses to aggressor cues. This response change is functionally important as optogenetic activation of aVMHvlOXTR cells elicits time-locked social avoidance towards a benign social target whereas inactivating the cells suppresses defeat-induced social avoidance. Furthermore, OXTR in the aVMHvl is itself essential for the behavior change. Knocking out OXTR in the aVMHvl or antagonizing the receptor during defeat, but not during post-defeat social interaction, impairs defeat-induced social avoidance. aVMHvlOXTR receives its private source of oxytocin from SOROXT cells, which are highly activated by the noxious somatosensory inputs associated with defeat. Oxytocin released from SOROXT depolarizes aVMHvlOXTR cells and facilitates their synaptic potentiation, and hence, increases aVMHvlOXTR cell responses to aggressor cues. Ablating SOROXT cells impairs defeat-induced social avoidance learning whereas activating the cells promotes social avoidance after a subthreshold defeat experience. Altogether, our study reveals an essential role of SOROXT-aVMHvlOXTR circuit in defeat-induced social learning and highlights the importance of brain oxytocin system in social plasticity. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Een heerlijk gevoel van extase. De geluksstofjes razen door je lichaam. Je voelt je fantastisch. En tegelijkertijd word je lichaam gezonder en veerkrachtiger. Dat is wat een duik in de zee, een ijsbad of zelfs een korte koude douche voor je kunnen doen. Huisarts en koudetrainer Monique Tjon-A-Tsien vertelt met zoveel liefde over de kou dat al je

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.09.27.509638v1?rss=1 Authors: Rosenberg, E., Chamberland, S., Bazelot, M., Nebet, E., Wang, X., McKenzie, S., Jain, S., Greenhill, S., Wilson, M., Salah, A., Bailey, S., Patra, P. H., Chenouard, N., Sun, S., Jones, D., Buzsaki, G., Devinsky, O., Woodhall, G., Scharfman, H., Whalley, B., Tsien, R. Abstract: Cannabidiol (CBD), a non-euphoric component of cannabis, reduces seizures in multiple forms of pediatric epilepsy, but the mechanism(s) of anti-seizure action remain unclear. In one leading model, CBD acts at glutamatergic axon terminals, blocking pro-excitatory actions of an endogenous membrane phospholipid, lysophosphatidylinositol (LPI), at the G protein-coupled receptor GPR55. However, the impact of LPI-GPR55 signaling at inhibitory synapses and in epileptogenesis remains underexplored. We found that LPI transiently increased hippocampal CA3 to CA1 excitatory presynaptic release probability and evoked synaptic strength in WT mice, while attenuating inhibitory postsynaptic strength by decreasing GABAAR gamma 2 and gephyrin puncta. Effects of LPI at both excitatory and inhibitory synapses were eliminated by CBD pretreatment and absent after GPR55 deletion. Acute pentylenetrazole-induced seizures elevated levels of GPR55 and LPI, and chronic lithium pilocarpine-induced epileptogenesis potentiated the pro-excitatory effects of LPI. We propose that CBD exerts potential therapeutic effect both by blocking synaptic effects of LPI and dampening hyperexcitability. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

Growing up in the 1950s in the only Chinese family in Berkeley Heights, New Jersey, Billie Tsien always felt like an outsider. She would seclude herself in the shower of her family’s home’s master bathroom, behind closed doors, escaping into books for hours before her parents, who had originally moved to America from Shanghai to study at Cornell, would find her. Through this Tsien developed a deep understanding of the value of a rich interior life—a concept she has gone on to apply to her work at the New York–based architectural practice Tod Williams Billie Tsien Architects Partners (TWBTA), which she co-founded with her husband, Tod Williams, in 1986. The ethereal craft inherent in TWBTA’s structures, which include parks, libraries, museums, and other people-focused places, emanates from Billie and Tod’s belief that architecture is an act of service, and an opportunity to create quiet moments where visitors can indulge in the simple yet powerful emotions that can be stirred when encountering beauty. When Tsien, now 72, reflects on her firm’s philosophy—which entails making buildings that transcend solutions, that respect the earth, and that are measured by the lives lived within them—it’s clear that she profoundly, even poetically, shapes each project’s awe-inspiring energy. Tsien’s deliberate, unhurried methodology is apparent in everything she does. She advocates for listening and community engagement—a central part of her firm’s high-profile, often controversial public works, such as Philadelphia’s Barnes Foundation (2012), Dartmouth College’s Hood Museum of Art (2019), and Chicago’s Obama Presidential Center, which is slated to break ground this fall. Tsien and her staff spend time with the craftspeople who create many of their materials—including Dutch textile artist Claudy Jongstra, whose vibrant felt paintings grace the walls of New York’s David Rubenstein Atrium (2009), and Danish brick-makers whose product features on the facade of dormitories at Pennsylvania’s Haverford College (2012)—and select them according to the emotional responses they elicit. She gives the same focused attention to the holistic experience of a building as she does the handrails that will go inside it. When it comes to the planet, Tsien thinks buildings should embrace measurable ways to minimize their environmental footprints as well as immeasurable ones, such as the meandering pathways of the LeFrak Center (2013), in Brooklyn’s Prospect Park, that invite people to appreciate the natural wonders around them.On this episode, Tsien details the origins of and rationale behind her approach to the built environment, talking with Spencer about designing structures as containers for life, why history doesn’t unfold in a straight line, and architecture as both an honor and a responsibility.

In this up close and personal conversation with Emmanuel Daniel, Samuel Tsien, Group CEO of OCBC Bank, reflected on his journey of building a well-diversified pan Asia financial services franchise. He revealed the leadership traits that served as the key to his success, and divulged his plans for the future when he relinquishes his role.

Jean Tsien has worked as a documentary editor for over 30 years with directors such as Orlando Bagwell, Barbara Kopple, and Roger Ross Williams. She's been a mentor to emerging filmmakers, not only in the U.S. but also in China and Taiwan where she lived until moving to New York at age 11. Now Jean has moved into producing. Her latest project is "76 Days," set in Wuhan, China during the city's lockdown for Covid-19. DOC NYC recently honored her with a Lifetime Achievement Award. Jean has stories to tell, but normally prefers to stay behind the scenes. Talking on a podcast? That's way outside her comfort zone. She explains why to Pure Nonfiction host Thom Powers.

Jean Tsien has worked as a documentary editor for over 30 years with directors such as Orlando Bagwell, Barbara Kopple, and Roger Ross Williams. She’s been a mentor to emerging filmmakers, not only in the U.S. but also in China and Taiwan where she lived until moving to New York at age 11. Now Jean has moved into producing. Her latest project is "76 Days," set in Wuhan, China during the city’s lockdown for Covid-19. DOC NYC recently honored her with a Lifetime Achievement Award. Jean has stories to tell, but normally prefers to stay behind the scenes. Talking on a podcast? That’s way outside her comfort zone. She explains why to Pure Nonfiction host Thom Powers.

To all intents and purposes although the word paper is the origin and historical development derived from papyrus, yet the two are produced very differently and the development of the first is distinct from the development of the second. Correspondingly, the fact that paper dates back almost 2,000 years to when inventors in China first crafted cloth sheets to record their drawings and writings. Moreover before then, global citizens communicated through pictures and symbols etched on stone, bones, cave walls, or clay tablets. And Paper as we know it today was first made in LeiYang, China by Ts'ai Lun, a Chinese court official. In all likelihood, Ts'ai mixed mulberry bark, hemp and rags with water, mashed it into pulp, pressed out the liquid, and hung the thin mat to dry in the sun."Paper technology : official journal of the Paper Industry Technical Association". WorldCat. Retrieved 10 January 2017. "papyrus". Dictionary.com Unabridged. Random House. Retrieved 20 November 2008. "Towards paperless information systems". CERN Document Server. Academic Press. 1978. Retrieved 2016-02-10. Habib, Irfan (2011). Economic History of Medieval India, 1200-1500. Pearson Education India. pp. 95–96. ISBN 9788131727911. https://www.jstor.org/journal/collegecouranthttps://www.jstor.org/stable/i40211191 W.C.Griffis https://www.synonyms.com/antonyms/understatement Murray, Stuart A. P. The Library: An illustrated History. Skyhorse Publishing, 2009, p. 57. SAK Ghori; A Rahman (1966). "Paper Technology in medieval India". Indian Journal of History of Science. 2: 135–136. Tsien 1985, p. 38 "PT V1 Nr1" (PDF). Paper Technology. Retrieved 13 July 2020. Archive". PITA. Retrieved 13 July 2020. Bloom, Jonathan (2001). Paper Before Print: The History and Impact of Paper in the Islamic World. New Haven: Yale University Press. pp. 8–10, 42–45. ISBN 0-300-08955-4. Burger, Peter (2007). Charles Fenerty and his paper invention. Toronto: Peter Burger. pp. 25–30. ISBN 978-0-9783318-1-8. OCLC 173248586. Archived from the original on 19 April 2009. Retrieved 19 May 2009. DeVinne, Theo. L. The Invention of Printing. New York: Francis Hart & Co., 1876. p. 134 Gittens, William Anderson, Author, Media Arts Specialist, Student of Film, License Cultural Practitioner Gittens,William Anderson,Author, Cinematographer,Dip., Com., Arts. B.A. Media Arts Specialists’ Editor-in-Chief Devgro Media Arts Services Publishing ®2015 License Cultural Practitioner, Publisher, CEO Devgro Media Arts Services®2015 http://www.digitaljournal.com/tech-and-science/technology/from-paper-to-the-press-two-technologies-that-changed-the-world/article/487825 http://www.scienceprojectideas.co.uk/testing-paper-for-strength.html https://education.jlab.org/qa/atomicstructure_11.html https://en.wikipedia.org/wiki/Environmental_impact_of_paper https://en.wikipedia.org/wiki/History_of_paper https://en.wikipedia.org/wiki/History_of_paper#CITEREFBarrett2008 https://en.wikipedia.org/wiki/History_of_paper#CITEREFTsien1985 https://en.wikipedia.org/wiki/History_of_paper#CITEREFWilkinson2012 https://en.wikipedia.org/wiki/History_of_paper#Shift_from_parchment_to_paper https://en.wikipedia.org/wiki/Industrial_Revolution#Paper_machine https://en.wikipedia.org/wiki/Main_Page https://en.wikipedia.org/wiki/Paper https://en.wikipedia.org/wiki/Paper#CITEREFBurns1996 https://en.wikipedia.org/wiki/Paper#CITEREFTsien1985 https://en.wikipedia.org/wiki/Paper#HistorSupport the show (http://www.buzzsprout.com/429292)

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.09.21.289314v1?rss=1 Authors: Park, C., Chen, X., Tian, C.-L., Park, G. N., Chenouard, N., Lee, H., Yeo, X. Y., Jung, S., Bi, G., Tsien, R. W., Park, H. Abstract: The balance between excitation and inhibition is essential for maintaining proper brain function in the central nervous system. Inhibitory synaptic transmission plays an important role in maintaining this balance. Inhibitory synaptic transmission faces greater kinetic demands than excitatory synaptic transmission, yet remains less well understood. In particular, the dynamics and exocytosis of single inhibitory vesicles have not been investigated due to both technical and practical limitations. Using quantum dots (QDs)-conjugated antibodies against the luminal domain of the vesicular GABA transporter (VGAT) to selectively label single GABAergic inhibitory vesicles and dual-focus imaging optics, we tracked single inhibitory vesicles up to the moment of exocytosis (i.e., fusion) in three dimensions in real time. Using three-dimensional trajectories, we found that the total travel length before fusion of inhibitory synaptic vesicles was smaller than that of synaptotagmin-1 (Syt1)-labeled vesicles. Fusion times of inhibitory vesicles were shorter compared with those of Syt1-labeled vesicles. We also found a close relationship between release probability to the proximity to fusion sites and total travel length of inhibitory synaptic vesicles. Furthermore, inhibitory synaptic vesicles exhibited a higher prevalence of kiss-and-run fusion than Syt1-labeled vesicles. Thus, our results showed that inhibitory synaptic vesicles have the unique dynamics and fusion properties that facilitate their ability to support fast synaptic inhibition. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.25.114389v1?rss=1 Authors: Liu, J.-J., Tsien, R. W., Pang, Z. P. Abstract: Neuropeptide melanin-concentrating hormone (MCH) plays important roles in the brain including control of energy homeostasis, sleep, learning and memory. However, the synaptic and circuitry mechanisms underlying MCH-mediated regulations remain largely unknown. Here, we uncover that MCH modulates the hippocampo (HP)-dorsal lateral septum (dLS)-lateral hypothalamus neural circuit to facilitate spatial learning and memory. MCH achieves this function by enhancing both excitatory and inhibitory synaptic transmission via presynaptic mechanisms. The dLS neuronal spiking activity in response to HP CA3 excitatory inputs is strongly controlled by feed-forward inhibition (FFI) mediated by both GABAA and GABAB receptors. Endogenous MCH signaling enhances Signal/Noise (S/N) ratio of dLS neurons by increase the excitatory strengths, meanwhile decrease the overall dLS excitability by enhance inhibition which reduces dLS FFI, and consequentially enables dLS neurons to fire with high fidelity with HP synaptic inputs. Our data unravel the multifaceted synaptic mechanisms of MCH in the defined HP-dLS circuitry which may contribute to learning and memory. Copy rights belong to original authors. Visit the link for more info

Dr Bill Nelson speaks with Dr Christina Tsien, Medical Director of the new Johns Hopkins Proton Therapy Center at Sibley Memorial Hospital, about the science behind proton therapy.

Host: Jenn Simmons, MD Guest: Clark C. Chen, MD, PhD Guest: David Piccioni, MD, PHD Guest: Christina I. Tsien, MD There is currently a high unmet need for treating high grade glioma, but is there hope on the horizon for more treatment alternatives? Joining Dr. Jenn Simmons to break down the current standard of care and potential treatments under investigation for high grade glioma are Dr. Clark Chen, Dr. Christina Tsien, and Dr. David Piccioni. ©2019 Tocagen. All rights reserved. VV-REG-003123 10/19

Host: Jenn Simmons, MD Guest: Clark C. Chen, MD, PhD Guest: David Piccioni, MD, PHD Guest: Christina I. Tsien, MD There is currently a high unmet need for treating high grade glioma, but is there hope on the horizon for more treatment alternatives? Joining Dr. Jenn Simmons to break down the current standard of care and potential treatments under investigation for high grade glioma are Dr. Clark Chen, Dr. Christina Tsien, and Dr. David Piccioni. ©2019 Tocagen. All rights reserved. VV-REG-003123 10/19

Host: Jenn Simmons, MD Guest: Clark C. Chen, MD, PhD Guest: David Piccioni, MD, PHD Guest: Christina I. Tsien, MD There is currently a high unmet need for treating high grade glioma, but is there hope on the horizon for more treatment alternatives? Joining Dr. Jenn Simmons to break down the current standard of care and potential treatments under investigation for high grade glioma are Dr. Clark Chen, Dr. Christina Tsien, and Dr. David Piccioni. ©2019 Tocagen. All rights reserved. VV-REG-003123 10/19

Host: Jenn Simmons, MD Guest: Clark C. Chen, MD, PhD Guest: David Piccioni, MD, PHD Guest: Christina I. Tsien, MD There is currently a high unmet need for treating high grade glioma, but is there hope on the horizon for more treatment alternatives? Joining Dr. Jenn Simmons to break down the current standard of care and potential treatments under investigation for high grade glioma are Dr. Clark Chen, Dr. Christina Tsien, and Dr. David Piccioni. ©2019 Tocagen. All rights reserved. VV-REG-003123 10/19

New York City architects Abby Suckle and William Singer are the authors of Cocktails and Conversations: Dialogues in Architectural Design.  AIA New York’s Center for Architecture has a great Friday night format:  invite people to to hear a famous architect paired with a master bartender who creates a custom cocktail to share with a thirsty audience.  Architects have included David Adjaye, Jeanne Gang, Peter Gluck, Frank Harmon, Tom Kundig, Daniel Libeskind, Eric Owen Moss, Billie Tsien, and Tod Williams, among many others. Host George Smart spoke with Abby and William at the Long Island Bar, 110 Atlantic Avenue, in Brooklyn. Joining them were David Moo and Toby Cecchini (inventor of the Cosmopolitan!), master bartenders behind all the cocktail creations.   About a month later, George and co-host Tom Guild met Australian Phillip Jones, the Martini Whisperer, poolside at the swanky Hotel Skylark in Palm Springs. For over a dozen years Jones worked as a fine dining manager and ran restaurants and events companies around the world.  Then he created a website for lovers of Martinis, craft spirits and cocktail culture with an Australian point of view.  In 2015 he gave the first ever TED talk on the Martini. And as he was leaving the Eau du Vie bar in Melbourne one fateful night, a lovely gang of actresses approached ....

On this episode, Matt spoke to Dr. Richard Tsien (Professor & Chair, New York University). Dr. Tsien has a diverse career, contributing many important findings to the field of cellular and molecular neuroscience, with a primary focus on understanding how the brain meets the demands to process information. Matt delved primarily into Dr. Tsien's path to becoming a scientist, and his advice for anyone interested in becoming a neuroscientist. The music on today's episode was by Robby. Check out their music at listentorobby.bandcamp.com

On this episode, Matt spoke to Dr. Richard Tsien (Professor & Chair, New York University). Dr. Tsien has a diverse career, contributing many important findings to the field of cellular and molecular neuroscience, with a primary focus on understanding how the brain meets the demands to process information. Matt delved primarily into Dr. Tsien's path to becoming a scientist, and his advice for anyone interested in becoming a neuroscientist. The music on today's episode was by Robby. Check out their music at listentorobby.bandcamp.com

We chat with Samuel Tsien, OCBC Group CEO on his plans for the bank's insurance arm Great Eastern.

We chat with Samuel Tsien, OCBC Group CEO how digital disruption is affecting his business.

We chat with Samuel Tsien, OCBC Group CEO about cryptocurrency and its plans for it.

Is the worst over for the Oil & Gas sector?  

The Breakfast Huddle chats with Samuel Tsien, OCBC Group CEO, on his outlook for 2018 and how rising interest ratse will impact us.

This is part 3 of the Breakfast Huddle's conversation with Samuel Tsien, OCBC Group CEO. He shares how OCBC is leveraging its Hong Kong assets to expand.

Fia de telefyzje kamen yn 1967 bylden fan in ferskriklike hongersneed yn Biafra yn de wenkeamers. Deasike bern mei aaklik tinne skonken en dikke opblaasde búkjes. Tsien fan harren waarden nei Nederlân ta helle. Asuquo, in jonkje fan tusken de 6 en 9 jier, kaam yn in refalidaasjesintrum yn Arnhem. Annie Gemser, de frou fan Henk Gemser wurke dêr en naam Asuquo yn de wykeinen mei nei hûs. Sa waard hy opnommen yn de húshâlding. Nei trije jier kaam fan hegerhân it befel dat Asuquo werom moast. Henk en Annie Gemser ha gehoar jûn oan dat befel en Asuquo gie werom nei Biafra, dat ûnderwilens Kongo hiet. Nei in healjier krige de famylje Gemser it berjocht dat Asuquo ferstoarn wie.

Fia de telefyzje kamen yn 1967 bylden fan in ferskriklike hongersneed yn Biafra yn de wenkeamers. Deasike bern mei aaklik tinne skonken en dikke opblaasde búkjes. Tsien fan harren waarden nei Nederlân ta helle. Asuquo, in jonkje fan tusken de 6 en 9 jier, kaam yn in refalidaasjesintrum yn Arnhem. Annie Gemser, de frou fan Henk Gemser wurke dêr en naam Asuquo yn de wykeinen mei nei hûs. Sa waard hy opnommen yn de húshâlding. Nei trije jier kaam fan hegerhân it befel dat Asuquo werom moast. Henk en Annie Gemser ha gehoar jûn oan dat befel en Asuquo gie werom nei Biafra, dat ûnderwilens Kongo hiet. Nei in healjier krige de famylje Gemser it berjocht dat Asuquo ferstoarn wie.

En 2008, los investigadores Shimomura, Chalfie y Tsien recibieron el Premio Nobel de Química “por el descubrimiento y desarrollo de la proteína fluorescente verde GFP”. Este descubrimiento tuvo su origen en la fluorescencia natural de la medusa Aequorea victoria, un ser que se agrupa en enormes cantidades en las aguas del Pacífico que bañan las costas de Norteamérica y las ilumina con un pálido resplandor azulado. El descubrimiento de GFP permitió desarrollar métodos para integrar la proteína en las células e iluminar los procesos bioquímicos que tienen lugar en ella. En el equipo de Robert Tsien, recientemente fallecido, trabajaba en nuestro invitado, Juan F. Llopis, director del Centro Regional de Investigaciones Biomédicas (CRIB) de la Universidad de Castilla – La Mancha. Hoy hablamos con él de proteinas fluorescentes.

A conversation with Dick Tsien on moving from cardiac physiology to LTP in a half-dozen years, conformational signaling by channels, and being a physiologist in the UK when Hodgkin, Huxley, and Katz were all doing experiments Download PDF transcript Key words: cardiac physiology, neuroscience, LTP, calcium channels, N-type channels, Denis Noble, Alan Hodgkin

We are delighted to devote the entirety of this episode to an interview with Tod Williams and Billie Tsien. Our discussion spanned their nearly 30 years (and counting) working together, focusing not on individual projects but their architectural philosophy, their material explorations, and their work with landscape. The rising cream throughout was the way Williams and Tsien talk with one another, each pulling on their side of the rowboat to craft a truly collaborative response.

Artist and Curator Ewen Chardronnet discusses with art historian Fabrice Lapelletrie their ongoing research around Frank Malina and his circles of friends and collaborators both in Pasadena around the work of the 'suicide club" headed by Malina with Jack Parsons, Ed Foreman. Hu Hse Tsien whose work led to the first successful American high altitude rockets, the founding of NASA JPL and Aerojet Gen Corporation. Malina then became known as a pioneer of kinetic art in Paris in the 1950s and 60s. Chardronnet discusses his ongoing research which has included visiting many of the foundational sites of American rocketry. Lapelletrie discusses the context of the birth of kinetic art in Paris in the 195os.

Nobel Laureates Robert Engle, Roger Tsien, Mario Molina and Harry Markowitz present synopses of their award-winning work and engage in a lively discussion on what it takes to move forward on promising ideas. This event is part of the Innovation Day Expo and Symposia (IDEaS) held in honor of UC San Diego’s 50th anniversary. Series: "IDEaS" [Public Affairs] [Science] [Show ID: 20830]

Nobel Laureates Robert Engle, Roger Tsien, Mario Molina and Harry Markowitz present synopses of their award-winning work and engage in a lively discussion on what it takes to move forward on promising ideas. This event is part of the Innovation Day Expo and Symposia (IDEaS) held in honor of UC San Diego’s 50th anniversary. Series: "IDEaS" [Public Affairs] [Science] [Show ID: 20830]

IDEaS - Nobel Laureate Roger Y. Tsien Series: "IDEaS" [Show ID: 21670]

IDEaS - Nobel Laureate Roger Y. Tsien Series: "IDEaS" [Show ID: 21670]