Podcasts about HP

                                   Copperplate Time 524                                presented by Alan O'Leary                             www.copperplatemailorder.com                                          My Glasgow Visit 1. BOTHY BAND:  Green Groves of Erin/Flowers of Red Hill. After Hours 2. JIMMY McHUGH: Pidgeon on the Gate.  2nd Jimmy McHugh Memorial Concert3. BRENDAN & MARTIN McHUGH:       MarionKelly's/Carey's Cottage.  2nd Jimmy McHugh Memorial Concert 4. BRIDGE CEILI BAND: Lord McDonald's/The Holly Bush/Finbarr Dwyer's.                          Sparks on Flags 5. PAUL McGLINCHEY & MACDARA O'RAGHALLAIGH:                 Lord Ramsey's/The Jolly Tinker/The Rainbows End.  Unearthed6. CHRISTY MOORE:  By Clyde's Bonnie Banks. Live in Dublin 7. KEVIN ROWSOME: The Musical Pulse  of the Blaskets.                     The Musical Pulse of the Pipes8. MICK MULVEY:  The Brook//The Killukin Ghost/Salute to Sherlock.              The Missing Guest 9. MICHAEL ROONEY & JUNE McCORMACK:           Colonel McBain's/Paddy Kiloran's.  Lands End 10. EILEEN O'BRIEN & LAR GAVIN:      The Poppy Leat/McIntyre's HP.   2nd Jimmy McHugh Memorial Concert 11. SEÁN ÓSÉ:  Do Bhí Bean Uasal.   O'Riada sa Gaiety 12. PJ CROTTY & JAMES CULLINANE:                    Sheep in the Boat/Hurry the Jug. Happy to Meet13. ANGELINA CARBERRY & DAN BRUDER:               Curlews in the Bog/Tommy People's/The Monsignor's Blessing.                    A Waltz for Joy 14. EILIS KENNEDY:   Ciumhais Charrig Aonair. So Ends This Day 15. PADDY CARTY & CONOR TULLY:                    Dowd's/In Memory of Coleman. Trad Music of Ireland 16. DERMOT BYRNE, JOHN DOYLE & EAMONN COYNE:                  Highland & Reels.  Liag 17. PJ & MARCUS HERNON:  Gallagher's Frolics/Tae ar an bPortach/An Buachaillin Bán.  Celebrating 50 Years 18. MICHAEL BANAHAN:  Winter in the City.   Broken Heart 19. CILLIAN VALLELY & DAVID DOOCEY:                    The Peacock's Feather.  The Yew & The Orchard 20. KEVIN BURKE & JOHN BRENNAN:                    London Town.   The Piound Ridge Sessions 21. BOTHY BAND: Green Groves of Erin/Flowers of Red Hill.   After Hours                                                 http://copperplatemailorder.com

Death in tabletop RPGs is a lot like a group project: everyone insists they're prepared for it, nobody actually reads the rules, and somehow it's always the wizard's fault. In this episode, the RPGBOT crew stares straight into the great beyond—death saves, dying conditions, resurrection magic, and those awkward moments when the cleric checks their spell slots and quietly says, "So… about that body." Whether your character goes out in a blaze of glory or bleeds out behind a crate because no one had an action left, we're breaking down how death really works at the table—and how to make it memorable instead of miserable. Show Notes Character death is one of the most emotionally charged—and mechanically misunderstood—parts of tabletop roleplaying games. In this episode of the RPGBOT.Podcast, the hosts dig into how death mechanics work across popular systems, why they often feel harsher (or softer) than intended, and how players and GMs can turn character death into a powerful storytelling moment instead of a buzzkill. The discussion covers death saves, dying conditions, instant death effects, and the role of healing magic in prolonging—or preventing—the inevitable. The crew examines how different RPG systems handle mortality, from forgiving safety nets to brutal attrition-based designs, and what those choices say about the kind of stories those games want to tell. Beyond raw mechanics, the episode explores meaningful death: heroic sacrifices, last stands, narrative consequences, and when resurrection magic enhances the story versus when it cheapens the moment. The hosts also share table-tested advice for GMs on foreshadowing danger, setting expectations, and making sure character death feels fair—even when it's devastating. If you've ever wondered whether death should be rare, frequent, reversible, or permanent—or why every party suddenly becomes a tactical mastermind the moment someone drops to zero HP—this episode is for you. Key Takeaways Death mechanics shape tone. How a system handles dying directly affects whether the game feels heroic, gritty, or forgiving. Death saves are drama engines. They create tension, spotlight teamwork, and often reveal who really read their character sheet. Instant death is rare—but memorable. When it happens, it should feel earned, telegraphed, or narratively significant. Resurrection is a storytelling tool. Bringing a character back should have consequences, costs, or complications to preserve emotional weight. Heroic sacrifice beats random loss. Deaths tied to player choice are almost always more satisfying than unlucky math. GM communication matters. Clear expectations about lethality prevent resentment and help players invest emotionally. Death doesn't end the story. It can launch new arcs, reshape the party, or permanently change the world. Welcome to the RPGBOT Podcast. If you love Dungeons & Dragons, Pathfinder, and tabletop RPGs, this is the podcast for you. Support the show for free: Rate and review us on Apple Podcasts, Spotify, or any podcast app. It helps new listeners find the best RPG podcast for D&D and Pathfinder players. Level up your experience: Join us on Patreon to unlock ad-free access to RPGBOT.net and the RPGBOT Podcast, chat with us and the community on the RPGBOT Discord, and jump into live-streamed RPG podcast recordings. Support while you shop: Use our Amazon affiliate link at https://amzn.to/3NwElxQ and help us keep building tools and guides for the RPG community. Meet the Hosts Tyler Kamstra – Master of mechanics, seeing the Pathfinder action economy like Neo in the Matrix. Randall James – Lore buff and technologist, always ready to debate which Lord of the Rings edition reigns supreme. Ash Ely – Resident cynic, chaos agent, and AI's worst nightmare, bringing pure table-flipping RPG podcast energy. Join the RPGBOT team where fantasy roleplaying meets real strategy, sarcasm, and community chaos. How to Find Us: In-depth articles, guides, handbooks, reviews, news on Tabletop Role Playing at RPGBOT.net Tyler Kamstra BlueSky: @rpgbot.net TikTok: @RPGBOTDOTNET Ash Ely Professional Game Master on StartPlaying.Games BlueSky: @GravenAshes YouTube: @ashravenmedia Randall James BlueSky: @GrimoireRPG Amateurjack.com Read Melancon: A Grimoire Tale (affiliate link) Producer Dan @Lzr_illuminati

#321 | Jess Cook, VP of Marketing at Vector, joins Dave to break down what's actually working in early-stage B2B marketing. They dig into how she thinks about attribution for brand channels, how Vector's podcast became a top marketing channel, why they created a brand mascot, and details on what content strategy is working on LinkedIn right now. They also cover shift from content leader to VP of Marketing and how to drive demand without a massive team or budget.Timestamps(03:06) - — Meet Jess Cook & What is Vector? (07:39) - — B2B Influencer pilot setup: why this channel, why now (14:57) - — The result: 45 demos, ~$1.1M pipeline, and how she tracked it (16:55) - — How to run influencers (22:20) - — Scaling idea: retainer-style influencer partnerships (26:00) - — Vector's podcast: “awareness magnet” and the format that works (28:24) - — The production system: in-person batch recording a full season in 2 days (42:10) - — Jess's LinkedIn strategy: why she started posting and what she optimizes for (53:58) - — Content → VP shift: the two muscles she's building (metrics + leadership) Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Have an idea or tip? Send us a text!A 1938 basement lab that processed black-and-white alongside amateur rolls now runs a high-speed digital operation that can ship school orders in about two days. The Dead Pixels Society sits down with Richmond Professional Lab's Ted Bullard and Josh Lewis to map the decisions that made digital not just viable, but superior, for volume photographers who demand both quality and speed.Bullard recounts how Kodak's consent decree opened the processing market and how Richmond leaned into professional work, long-roll film, and eventually early digital printers. Then Lewis pulls back the curtain on the operational engine: why fewer, faster machines beat a fleet of minis, how custom software gangs tens of thousands of orders, and why posting live turnaround times builds trust during peak seasons. They share into the Canon DreamLabo journey, HP ink and laminate advances, and the color fidelity and longevity that finally matched—then surpassed—silver halide expectations.The volume landscape is shifting fast, with independents stepping in where a major player receded. That opens space for smarter products and sharper margins: yard signs, big head cutouts, layered graphics, and ship-to-home convenience that schools and parents now prefer. We talk daPhoto Imaging CONNECTThe Photo Imaging CONNECT conference, March 1-2, 2026, at the RIO Hotel and Resort in Las Vegas, NMaking Good: Small Business Marketing PodcastMaking Good helps you do better marketing so you can make a bigger impact. If you're...Listen on: Apple Podcasts SpotifyMediaclipMediaclip strives to continuously enhance the user experience while dramatically increasing revenue.Buzzsprout - Let's get your podcast launched!Start for FREEIndependent Photo ImagersIPI is a member + trade association and a cooperative buying group in the photo + print industry.Photo Imaging CONNECTThe Photo Imaging CONNECT conference, March 1-2, 2026, at the RIO Hotel and Resort in Las Vegas, NDisclaimer: This post contains affiliate links. If you make a purchase, I may receive a commission at no extra cost to you.Support the showSign up for the Dead Pixels Society newsletter at http://bit.ly/DeadPixelsSignUp.Contact us at gary@thedeadpixelssociety.comVisit our LinkedIn group, Photo/Digital Imaging Network, and Facebook group, The Dead Pixels Society. Leave a review on Apple and Podchaser. Are you interested in being a guest? Click here for details.Hosted and produced by Gary PageauAnnouncer: Erin Manning

While many people talk about mentorship, HP's Chief IP Counsel Ceyda Maisami and Tradespace's VP of IP Operations & Client Success Marcia Chang actually live it.In this episode, Ceyda and Marcia join Clause 8 host Eli Mazour for a wide-ranging conversation about mentorship, what it really takes to run IP teams inside large technology companies, and what the rise of AI means for both in-house and outside counsel.They share the story of how they first met at HP, why Ceyda credits Marcia with the advice and encouragement that helped her grow into the Chief IP Counsel role, and what that guidance looks like in practice for other in-house lawyers navigating their own careers.The conversation also dives into HP's experience with high-stakes litigation and how those lessons shape its global patent portfolio strategy. Ceyda also offers a behind-the-scenes look at HP's IP team restructure—why early attempts fell short and what finally made the new model work. The discussion delivers practical takeaways for anyone building or leading an in-house IP team, balancing portfolio development with business goals, or working to make IP more central to company decisions.The episode closes with a candid, practical discussion of AI—what it means for the expectations placed on outside counsel, how in-house teams are already using it, and what lawyers need to do to continue delivering real value as the pace of work accelerates.Together, Ceyda and Marcia offer a rare, grounded look at mentorship, leadership, and the future of IP inside major tech companies.

Callum McMenamin (OpenAccess) joins host Paul Spain to unpack Manage My Health data breach, exploring critical shortcomings in cybersecurity and the lack of mandatory multi-factor authentication. They also cover Kereru.ai's sovereign AI project with SCX.ai, plus CES 2026 highlights including gadgets, LG's CLOiD chore robot, LEGO's sensor‑packed Smart Bricks, Boston Dynamics' production Atlas, Intel's Core Ultra Series 3 comeback bid, Nvidia's Alpamayo autonomous driving platform and CES 2026 “Worst in Show”. Plus Kindle Colorsoft review and more.Thanks to our Partners One NZ, Workday, 2degrees, HP, Spark and Gorilla Technology

Analyse des principales actualités technologiques CES 2026 : innovations marquantes comme les écrans extensibles, les aspirateurs robots, les lunettes connectées, avec un regard critique sur certaines technologies inutiles. Évaluation des promesses d'Apple autour d'un Creator Studio, des enjeux liés à l'intelligence artificielle et à la désinformation, ainsi que de l'influence d'Elon Musk.  Patreon YouTube Discord Interactions, suivis et à chaud Les frigos jettent un froid. “Clarifications” du dernier épisode d'Office Apple Creator Studio Ça, CES fait CES finis : le bilan de la cuvée 2026 ? Whoa, Blackberry, bam-ba-lam ! Les ordinateurs portables du CES : toujours plus ! Lenovo (qui n'a pas lu Death Note) met Qira dans ses machines. Intel veut son Z1 Extreme et du HDR partout ! HP nous fait un CPC. Les lunettes, c'est trop chouette ! Mmmm Donut ! La révolution arrive, sur deux roues. Et sinon l'écologie tout ça ? Les aspirateurs du CES toujours plus robotiques. Métro boulot, robot : Atlas à l'usine, Wall-E en vrai et Unitree au dojo. Le Pire du Salon : les abominations Les batteries… avec économiseur d'écran. Un casque audio… avec des caméras. Chatgtpop : collectionnez les tous ! Et brûlez-les. Tableau d'horreur : TCL se lance dans la TV “artistique”. Le Pire du Salon : la sélection de Satan Lollipop star : la sucette qui chante dans ta bouche. Les vélos sont des iPhone comme les autres. Et aussi le tapis de marche mouchard, l'app Store de Ring et le frigo vocal. C'est déjà 2049 : Emily pas encore in Paris. À mines et à Police ICE, VenezuelIA : internet devient un champ de mines. Image pédo : une réponse de X “en demi-teinte”. Elon a beaucoup trop fumé… Jeux vidéo GameStop, le nouveau Tesla. Le prix de la Steam Machine pourrait donner des vapeurs. Toss a coin to your witcher : un nouveau DLC pour… The Witcher 3. Participants Une émission préparée par Guillaume Poggiaspalla Présenté par Guillaume Vendé

出演者：藤原鞠菜 配信ペース：隔週火曜日 番組時間：平均40分 ——————————————————————— ＜各テーマ紹介＞配信されるテーマは回によって異なります。 「ふつおた」･･･何でもありのお便りコーナー。投稿は毎日募集中！！！！！ 「歴史秘話ウィステリア」･･･サークル曲の裏話など。 「まりにゃのこれな～んだ？」･･･音当てクイズ。 「まりにゃのオススメ」･･･オススメ商品をご紹介。 「はじおと」･･･「音楽」×「初めて」に関して語るコーナー。 （初めて買ったCD、初めて心を動かされた音楽、初めてカラオケで歌った曲等。） 「これかた」･･･テーマを決めて語る割とフリーダムなコーナー。 （テーマや語ってみた投稿募集中。） 「答えて、まりにゃ」･･･まりにゃへの質問募集中。 「トレンドなう」･･･収録時に開いたTwitterのリアルタイムトレンドについてコメント。 「まりにゃのTOP5」･･･思いついたら勝手にランキング。 「まりにゃのドキドキ質問箱」…twitter投稿になります。（ https://peing.net/marinya_）  「みんなの答え合わせ」…twitterで出題するアンケートの結果報告。みんなに聞きたいこと募集中。 ——————————————————————— ——————————————————————— ■CD新作・出演告知など■ ★Wisteria Magic通販サイト「うぃすましょっぷ」★ wismashop.booth.pm/ 新作も旧作も全て送料込み！ ★イオシスショップ様にて一部旧作を委託販売中！★ www.iosysshop.com/SHOP/list.php?Search=wisteria ★しがないレコーズのyoutube「しがない5分ショー」に出演してます。 藤原鞠菜は木曜日担当です。 https://www.youtube.com/channel/UCA_FmkoMu24R_6o3m3_Ulqg —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ・の〜すとらいく様の18禁PCゲーム 「女装百合畑/Trap Yuri Garden」にて、主題歌「優雅にヒロイン宣言」を担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして！夜までもっとエッチして！」 にて女未こはくちゃん(三女)のED曲担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして!」 にて女未こはくちゃん(三女)のED曲を担当させて頂きました。 —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ——————————————————————— この番組は音楽サークルWisteria Magicがお届けする番組です。 藤原鞠菜やサークルの過去または最新の活動内容につきましては 以下をチェックしてくださると嬉しいです♪ ・藤原鞠菜のTwitter（ twitter.com/marinya_ ） ・藤原鞠菜のHP「ふじわらんど」（ fujimari.com/ ） ・磯村カイのTwitter（ twitter.com/isomurakai ） ・磯村カイのHP「TONAKAI soundworks」（ https://soundworks.tonakaii.com/ ） 藤原鞠菜への贈り物の宛先 〒107-0052 東京都港区赤坂4-9-25 新東洋赤坂ビル10F レイズイン　アカデミー気付　藤原鞠菜宛 VOICEVOX:ずんだもん VOICEVOX:四国めたん

Stage Eight of the Dakar Rally 2026 pushes the field deeper into the second half of the rally, delivering a long and demanding day that places equal emphasis on navigation, tire management, and strategy.In this Stage 8 briefing, Victor Orellana breaks down a 721-kilometer day, featuring a challenging mix of dirt tracks, sand, and rocky sections that continue to test both riders and machines. With stony terrain already proving tough on tires this year, durability and decision-making become critical.Navigation plays a major role once again, with alternating tracks and HP navigation sections that can quickly catch competitors out. Combined with the introduction of mid-stage tire changes, Stage 8 rewards those who manage pace intelligently rather than pushing blindly.This episode covers:Full Stage 8 course overviewTerrain mix and what it means for speed and fatigueWhy navigation accuracy is decisiveTire management challenges on stony tracksTiming details, including the early 5:10 AM bike startStrategic considerations as Dakar 2026 moves into its later stagesStage 8 may not look extreme on paper, but like many Dakar stages, it's designed to punish in subtle ways. As the rally progresses, preparation and discipline matter more than ever.

#320 | Matt Carnevale, Head of Community at Exit Five, joins Dave for a discussion about community building. They dive into a bunch of the lessons learned from building the Exit Five community over the last few years, including specific plays like onboarding, matchmaking, and moderation. If you're thinking about community building in 2026, this is a good primer; plus the guys give their opinion on what “community” actually means and whether you should build a private community like Exit Five or focus more broadly on community building.Timestamps(00:02) - – Matt's path from BDR to Head of Community at Exit Five (08:29) - – What “community” actually means (and what it definitely isn't) (13:14) - – Why most B2B communities fail before they ever get traction (17:54) - – Community vs. content: what gets people in vs. what makes them stay (22:29) - – Why Slack groups aren't a strategy (27:14) - – Treating community like a product, not a marketing channel (34:48) - – The role of trust, curation, and saying no to the wrong people (40:23) - – What community managers actually do behind the scenes (47:18) - – How in-person events changed the Exit Five community (53:28) - – The biggest lessons Matt's learned after two years building Exit Five Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

In this episode, Mike “C-Roc” sits down with Chris Christensen, creator of AmateurTraveler.com, Podcasting Hall of Fame inductee, and one of the true pioneers of modern podcasting. With more than 20 years behind the mic, Chris shares how curiosity has been the defining force of his life—from his early career in high tech and web development at companies like HP, IBM, and TripAdvisor, to launching one of the world's longest-running and most downloaded travel podcasts, which reached over 1.78 million downloads in 2024 alone. The conversation explores the evolution of technology, podcasting, and AI, with Chris offering thoughtful insight into how innovation has changed over the decades and where it's headed next. He also reflects on how a childhood spent road-tripping to national parks sparked a lifelong passion for travel, ultimately leading him to interview travelers from around the world and experience destinations many only dream of. Equal parts thoughtful, informative, and inspiring, this episode reveals what Chris Christensen is truly made of—and how curiosity can shape an extraordinary career andWebsite: https://AmateurTraveler.com Social Media Links/Handles-https://www.instagram.com/chris2x/?hl=enhttps://www.tiktok.com/@amateurtraveler

CES 2026 brought notable innovations for filmmakers and media professionals. In this episode, we break down the most interesting tech: Fujifilm's new instax mini Evo Cinema Camera with vintage film emulation, LEGO's impressive computer-integrated Smart Brick, HP's EliteBoard keyboard computer, Boston Dynamics' fully electric Atlas robot, Samsung's thin 3D display technology, and Nvidia's Rubin platform advances. --The views and opinions expressed in this podcast are the personal views of the hosts and do not necessarily reflect the views or positions of their respective employers or organizations. This show is independently produced by VP Land without the use of any outside company resources, confidential information, or affiliations.

Habitat Podcast #366 - In today's episode of The Habitat Podcast, we are back in the studio with the HP crew Andy Hutchens, Matt Zahl, and Corey Franceus! We discuss: Soil improvement takes years longer than most landowners expect Access mistakes ruin more farms than poor habitat choices Switchgrass is useful—but often overused for bedding Living on your property helps hunters more than deer Cutting harder early speeds up timber regeneration Water control quietly dictates deer movement and use Less hunting pressure beats perfect habitat design Food plots help hunters more than deer if misused Small properties win by being different than neighbors Mature bucks survive pressure better than most think And So Much More! Shop the new Amendment Collection from Vitalize Seed here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://vitalizeseed.com/collections/new-natural-amendments ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ PATREON - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Patreon - Habitat Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Brand new HP Patreon for those who want to support the Habitat Podcast. Good luck this Fall and if you have a question yourself, just email us @ info@habitatpodcast.com -------------------------------------------------------------------------- ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Patreon - Habitat Podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Latitude Outdoors - Saddle Hunting: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/hplatitude⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Stealth Strips - Stealth Outdoors: Use code Habitat10 at checkout ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/stealthstripsHP⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Midwest Lifestyle Properties - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/3OeFhrm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Vitalize Seed Food Plot Seed - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/vitalizeseed⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Down Burst Seeders - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/downburstseeders⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 10% code: HP10 Morse Nursery - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://bit.ly/MorseTrees⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 10% off w/code: HABITAT10 Packer Maxx - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://bit.ly/PACKERMAXX⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ $25 off with code: HPC25 First Lite - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bit.ly/3EDbG6P⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ LAND PLAN Property Consultations – HP Land Plans: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LAND PLANS⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Leave us a review for a FREE DECAL - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://apple.co/2uhoqOO⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Morse Nursery Tree Dealer Pricing – info@habitatpodcast.com Habitat Podcast YOUTUBE - ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/channel/UCmAUuvU9t25FOSstoFiaNdg⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Email us: info@habitatpodcast.com habitat management / deer habitat / food plots / hinge cut / food plot Learn more about your ad choices. Visit megaphone.fm/adchoices

Explore the most exciting announcements from CES 2026 with Steven Scott, Shaun Preece, and guest Marc Aflalo. From HP's all-in-one keyboard computer to AI-ready laptops, haptic wearables, and Braille label printers, this episode dives into the real-world impact of emerging tech for both mainstream and accessible use.This episode is supported by Pneuma Solutions. Creators of accessible tools like Remote Incident Manager and Scribe. Get $20 off with code dt20 at https://pneumasolutions.com/ and enter to win a free subscription at doubletaponair.com/subscribe!CES 2026 delivered everything from cutting-edge laptops and AI-driven devices to innovative accessibility tools. Steven, Shaun, and Marc discuss why HP's G1 keyboard computer could be a game-changer for blind users, and how Dell's new XPS series is stepping away from the “AI ready” branding. They also explore haptic wristbands for Meta Ray-Bans, Rokid's AR glasses, and the Mnemonic Braille Label Printer, questioning both mainstream potential and accessibility.The conversation highlights how tech marketing often misses accessibility opportunities, and why CES's new Accessibility Stage is a vital step in changing that. Plus, the team debate neural bands, AI in laptops, and the growing overlap between mainstream and assistive technologies. Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

#319 | Dave sits down with Jess Lytle, Head of Marketing at Exit Five, to talk about how AI is changing the job of B2B marketers and the reality of how AI is actually being adopted internally. They also cover how AI even helped Jess get her job at Exit Five and why she's become obsessed about deploying AI in marketing and really believes this is the most important martech wave yet. Timestamps(00:00) - – Goals, manifestation, and reverse-engineering outcomes (06:14) - – Meet Jess Lytle, Head of Marketing at Exit Five (08:28) - – How Jess got hired at Exit Five (webinar → DMs → job) (10:28) - – From demand gen to AI: early adoption, teaching, and Lovable (15:58) - – Why AI feels different than traditional martech (18:28) - – Content in 2026: originality, human insight, and AI distribution (29:16) - – NotebookLM: real marketing workflows and internal use cases (35:16) - – AI tools, team structure, and hybrid marketer roles (45:56) - – Working at Exit Five, founder-led marketing, and brand bets Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Dr. Monty Pal and Dr. Hope Rugo discuss advances in antibody-drug conjugates for various breast cancer types as well as treatment strategies in the new era of oral SERDs for HR-positive breast cancer. TRANSCRIPT Dr. Monty Pal: Hello, and welcome to the ASCO Daily News Podcast. I'm your host, Dr. Monty Pal. I'm a medical oncologist and vice chair of academic affairs here at the City of Hope Comprehensive Cancer Center, Los Angeles. Today, I'm thrilled to be joined by Dr. Hope Rugo, an internationally renowned breast medical oncologist and my colleague here at City of Hope, where she leads the Women's Cancers Program and serves as division chief of breast medical oncology. Dr. Rugo is going to share with us exciting advances in antibody-drug conjugates (ADCs) that are expanding treatment options in various breast cancer types. She'll also address some of the complex questions arising in the new era of oral SERDs (selective estrogen receptor degraders) that are revolutionizing treatment in the hormone receptor-positive breast cancer space. Our full disclosures are available in the transcript of this episode.  Dr. Rugo, welcome, and thanks so much for being on the podcast today. Dr. Hope Rugo: Thank you. Pleasure to be here. Dr. Monty Pal: So, I'm going to switch to first names if you don't mind.  The first topic is actually a really exciting one, Hope, and this is antibody-drug conjugates. I don't know if I've ever shared this with you, but I actually started my training at UCLA, I was a med student and resident there, and it was in Dennis Slamon's lab. I worked very closely with Mark Pegram and a handful of others. This is right around the time I think a lot of HER2-directed therapies were really evolving initially in the clinics. Now we've got antibody-drug conjugates. Our audience is well-familiar with the mechanism there but tell us about how ADCs have really started to reshape therapy for HER2-positive breast cancer. Dr. Hope Rugo: Yeah, I mean, this is a really great place to start. I mean, we have had such major advances in breast cancer just this year, I think really changing the paradigm of treating patients. But HER2-positive disease, we've been used to having sequenced success of new agents. And I think the two biggest areas where we've made advances in HER2-positive disease, which were remarkably advanced this year in 2025, have been in antibody-drug conjugates with trastuzumab deruxtecan and with new oral tyrosine kinase inhibitors (TKIs) that have less of a target on EGFR and more on HER2, so they have an overall more tolerable toxicity profile and therefore a potentially better efficacy in the clinic. At least that's what we're seeing with these new strategies that we couldn't really pursue in the past because of toxicities of the oral TKIs. So, although our topic is ADCs, I'm going to include the TKI because it's so important in our thinking about treating HER2-positive disease. In the metastatic setting, we've seen these remarkable improvements in progression-free and overall survival in the second-line setting with T-DXd, or trastuzumab deruxtecan, compared to T-DM1. And then sequencing ADCs with giving T-DXd after T-DM1 was better than an oral tyrosine kinase or a trastuzumab combination with standard chemotherapy. That was DESTINY-Breast03 and DESTINY-Breast02. So, then we've had other trials since then, and T-DXd has moved into the early-stage setting, which I'll talk about in just a moment. But the next big trial for T-DXd in HER2-positive disease was moving it to the first-line setting to supplant what has become an established treatment for now quite a long time: the so-called CLEOPATRA regimen, which used the combined antibodies trastuzumab, pertuzumab with a taxane as first-line therapy. And then we've proceeded on with maintenance with ongoing HP for patients with responding or stable disease. And we'd seen long-term data showing, you know, at 8 years there was a group of patients whose cancers had never progressed and continued improved overall survival. So, T-DXd was studied in DESTINY-Breast09, either alone or in combination with pertuzumab compared to THP. The patient population had received a little bit more prior treatment, but interestingly, not a lot compared to CLEOPATRA. And they designed the trial to be T-DXd continued until progression with or without pertuzumab versus THP, which would go for six cycles and then stop around six cycles, and then stop and continue HP. Patients who had hormone receptor-positive disease could use hormone therapy, and this is one of the issues with this dataset because, surprisingly in this dataset and one other I'll mention, very few patients took hormone therapy. And even in the maintenance trial, the HER2CLIMB-05, less than 50% took hormone therapy as maintenance. This is kind of shocking to me and highlights an area of really important education, that outcome is improved when you add endocrine therapy for hormone receptor-positive HER2-positive metastatic disease in the maintenance phase, and it's a really important part of treatment. But suffice it to say, you know, you're kind of studying continued chemo versus stopping chemo in maintenance. And T-DXd, as we all expected, in combination with pertuzumab was superior to THP in terms of progression-free survival, really remarkably improved. And you could stop the chemo with toxicity, but most people continued it with T-DXd. Again, not a lot of people got hormone therapy, which is an issue, and you stop the chemo in the control arm. So, this has brought up a lot of interest in trying to use T-DXd as an induction and then go to maintenance, much as we do with the CLEOPATRA regimen with hormone therapy. But it brings up another issue. So first, T-DXd is superior; it's a great treatment. Not everybody needs to have it because we don't know whether it's better to give T-DXd first or second with progression - that we need a little bit longer follow-up. But just earlier this week, interestingly, the third week of December, the U.S. FDA approved T-DXd in the DESTINY-Breast09 approach with pertuzumab. So as I mentioned earlier, there was a T-DXd-alone arm; that arm has not yet reported. So very interesting, we don't know if you need pertuzumab or not. So what about the maintenance? That's the other area where we've made a huge advance here. So, we all want to stop chemo and we want to stop T-DXd. You don't want somebody being nauseated for two years while they're on treatment, and also there's a small number of patients with mostly de novo metastatic HER2-positive disease who are cured of their disease. We'd like to expand that, and I think these new drugs give us the opportunity to improve the number of patients who might be cured from metastatic disease. So the first maintenance study we saw was adding palbociclib, the CDK4/6 inhibitor, to endocrine therapy and HP, essentially. There, we had a remarkable improvement in progression-free survival difference of 15.2 months: 29 to 44 months, really huge. At San Antonio this year, we saw data with this oral tyrosine kinase inhibitor tucatinib, already showed it was great in a triplet, but as maintenance in combination with HP, it showed also a remarkable improvement in progression-free survival. But the numbers were all shifted down. So in PATINA, the control arm was in the 24-month range; here it was the tucatinib-HP arm that was in the 25 months and 16 months for control. So there was a differential benefit in ER-negative and ER-positive disease. So I think we're all thinking that our ideal approach moving forward would be to give T-DXd to most patients, we see how they do, and treat to best response. And then, stop the T-DXd, start HP, trastuzumab, pertuzumab for ER-negative, with tucatinib for ER-positive with palbociclib. We also have early data that suggests that both approaches may reduce the development of brain metastases, an issue in HER2-positive disease, and delay time to progression of brain metastases as seen in HER2CLIMB-05 in very early data - small numbers, but still quite intriguing that you might delay progression of brain metastases with tucatinib that clearly has efficacy in the brain.  So, I think that this is a hugely exciting advance for our patients, and these approaches are quickly moving into the early stage setting. T-DXd compared to standard chemo, essentially followed by THP, so a sequenced approach resulted in more pathologic complete responses than a standard THP-AC-type neoadjuvant therapy. T-DXd alone for eight cycles wasn't better, and that's interesting. We still need the sequenced non-cross-resistant chemo. But I think even more importantly, the data from DESTINY-Breast05 looking at T-DXd versus T-DM1 in patients with residual disease after neoadjuvant HER2-targeted therapy showed a remarkable improvement in invasive disease-free survival with T-DXd versus T-DM1, and quite early. It was a high-risk population, higher risk than the T-DM1 trial with KATHERINE, but earlier readout with a remarkable improvement in outcome. We expect to be FDA approved sometime in the first half of 2026. So then we'll get patients who've already had T-DXd who get metastatic disease. But my hope is that with T-DXd, maybe with tucatinib in the right group of patients or even sequenced in very high-risk disease, that we could cure many more patients with early-stage HER2-positive breast cancer and cure a subset, a greater subset of patients with de novo metastatic disease. Dr. Monty Pal: That's brilliant. And you tackled so many questions that I was going to follow up with there: brain metastases, etc. That was sort of looming in my mind. I mean, general thoughts on an ADC versus a TKI in the context of brain mets? Dr. Hope Rugo: Yeah, it's an interesting question because T-DXd has shown quite good efficacy in this setting. And tucatinib, of course, had a trial where they took patients with new brain mets, so a larger population than we've seen yet for the T-DXd trials, and saw that not only did they delay progression of brain metastases and result in shrinkage of existing untreated brain mets, but that patients who develop a new brain met, they could stay on the same assigned treatment. They got stereotactic radiation, and then the patients who were on tucatinib with trastuzumab and capecitabine had a further delay in progression of brain mets compared to those on the placebo arm, even after treatment of a new one that developed on treatment. So, I think it's hard. I think most of us for a lot of brain mets might start with the tucatinib approach, but T-DXd is also a very important treatment. You know, you're kind of trading off a diarrhea, some liver enzyme elevations with tucatinib versus nausea, which you really have to work on managing because it can be long-delayed nausea, and this risk of ILD, interstitial lung disease, that's about 12%, with most but not all trials showing a mortality rate from interstitial lung disease of just under 1 percent. In the early-stage setting, it was really interesting to see that with T-DXd getting four cycles in the neoadjuvant setting, a lot less ILD noted than the patients who got up to 14 cycles, as I think they got a median of 10 cycles in the post-surgical setting, there was a little bit more ILD. But I think we're going to be better and better at finding this earlier and preventing mortality by just stopping drug and treating earlier with steroids. Dr. Monty Pal: And this ILD issue, it always seems to resurface. There are drugs that I use in my kidney cancer clinic, everolimus, common to perhaps the breast cancer clinic as well, pembrolizumab, where I think the pattern of pneumonitis is quite different, right? What is your strategy for recognizing pneumonitis early in this context? Dr. Hope Rugo: Well, it is, and you know, having done the very early studies in everolimus where we gave it in the neoadjuvant setting and we're like, "Hmm, the patient came in with a cough. What's going on?" You know, we didn't know. And you have mouth sores, you know, we were learning about the drug as we were giving it. What we don't do with everolimus and CDK4/6 inhibitors, for example, is grade 1 changes like radiation pneumonitis, we don't stop, we don't treat it. We only treat for symptoms. But because of the mortality associated with T-DXd, albeit small, we stop drug for grade 1 imaging-only asymptomatic pneumonitis, and some of us treat with a half dose of steroids just to try and hasten recovery. We've actually now published or presented a couple of datasets from trials, a pooled analysis and a real-world analysis, that have looked at patients who were retreated after grade 1 pneumonitis or ILD and tolerated drug very well and none of them died of interstitial lung disease, which was really great to see because you can retreat safely and some of these patients stayed on for almost a year benefiting from treatment. So, there's a differential toxicity profile with these drugs and there are risk factors which clearly have identified those at higher risk: prior ILD, for example. A French group said smoking; other people haven't found that, maybe because they smoked more in France, I don't know. And being of Japanese descent is quite interesting. The studies just captured that you were treated in Japan, but I think it's probably being of Japanese descent with many drugs that increases your risk of ILD. And, you know, older patients, people who have hypoxia, those are the patients. So, how do we do this? With everolimus, we don't have specific monitoring. But for T-DXd we do; we do every nine weeks to start with and then every 12 weeks CT scans because most of the events occur relatively early. Somebody who's older and at higher risk now get the first CT at six weeks. Dr. Monty Pal: This is super helpful. And I have to tell you, a lot of these drugs are permeating the bladder cancer space which, you know, is ultimately going to be a component of my practice, so thank you for all this. We could probably stay on this topic of HER2-positive disease forever. I'm super interested in that space still. But let me shift gears a little bit and talk about triple-negative breast cancer and this evolving space of HR-positive, HER2-low breast cancer. I mean, tell us about ADCs in that very sort of other broad area. Dr. Hope Rugo: So triple-negative disease is the absolute hardest subset of disease that we have to treat because if you don't have a great response in the early stage setting, the median survival is very short, you know, under two years for the majority of TNBCs, with the exception of the small percentage of low proliferative disease subsets. The co-question is what do we do for these patients and how do we improve outcome? And sacituzumab govitecan has been one strategy in the later line setting that was shown to improve progression-free and overall survival, the Trop-2 ADC. We had recently three trials presented with the two ADCs, sacituzumab govitecan and the other Trop-2 ADC that's approved for HR-positive disease, datopotamab deruxtecan. And they were studied in the first-line setting. Two trials with SG, sacituzumab govitecan, those trials, one was PD-L1 positive, ASCENT-04. That showed that SG with a checkpoint inhibitor was superior, so pembrolizumab was superior to the standard KEYNOTE-355 type of treatment with either a taxane or gemcitabine and carboplatin with pembrolizumab for patients who have a combined positive score for PD-L1, 10 or greater. So, these are patients who are eligible for a checkpoint inhibitor, and SG resulted in an improved progression-free survival.  The interesting thing about that dataset is that few patients had received adjuvant or neoadjuvant checkpoint inhibitor, which is fascinating because we give it to everybody now. But access is an issue and timing of the study enrollment was an issue. The other thing which I think we've all really applauded Gilead for is that there was automatic crossover. So, you could get from the company, to try and overcome some of the enormous disparities worldwide in access to these life-saving drugs, you could get SG through the company for free once you had blinded independent central review confirmation of disease progression. Now, a lot of the people who got the SG got it through their insurance, they didn't bill the company, but 80 percent of patients in the control arm received SG in the second-line setting. So that impacts your ability to look at overall survival, but it's an incredibly important component of these trials. So then at ESMO, we saw the data from SG and Dato-DXd in the first-line metastatic setting for patients who either had PD-L1-negative disease or weren't eligible for an immunotherapy. For the Dato study, TROPION-Breast02, that was 10 percent of the patients who had PD-L1-positive disease but didn't get a checkpoint inhibitor, and for the ASCENT-03 trial population it was only 1 percent. Importantly, the trials allowed patients who relapsed within a year of receiving their treatment with curative intent, and the Dato study, TB-02, allowed patients who relapsed while on treatment or within the first six months, and that was 15 percent of the 20 percent of early relapsers. The ASCENT trial, ASCENT-03, had 20 percent who relapsed between 6 and 12 months. The drugs were better than standard of care chemotherapy, the ADCs in both trials, which is very nice. Different toxicity profiles, different dosing intervals, but better than standard of care chemotherapy in the disease that's hardest for us to treat. And importantly, when you looked at the subset of early relapsers, those patients also did better with the ADC versus chemotherapy, which is incredibly important. And we were really interested in that 15 percent of patients who had early relapse. I actually think that six months thing was totally contrived, invented, you know, categorization and doesn't make any sense, and we should drop it. But the early relapsers were 15 percent of TB-02 and Dato was superior to standard of care chemo. We like survival, but the ASCENT trial again allowed the crossover to an approved ADC that improved survival and 80 percent of patients crossed over. In the Dato trial, they did not allow crossover, they didn't provide Dato, which isn't approved for TNBC but is for HR-positive disease, and they didn't allow, of course, pay for SG. So very few patients actually crossed over in their post-treatment data and in that study, they were able to show a survival benefit. So actually, I think in the U.S. where we can use approved drugs already before there's a fixed FDA approval, that people are already switching to use SG or Dato in the first-line setting for metastatic TNBC that's both PD-L1 positive for SG and PD-L1 negative for both drugs. And I think understanding the toxicity profiles of the two drugs is really important as well as the dosing interval to try and figure out which drug to use. Dr. Monty Pal: Brilliant. Brilliant. Well, I'm going to shift gears a little bit. ADCs are a topic, again, just like HER2-positive disease we could stay on forever. Dr. Hope Rugo: Huge. Yes. Dr. Monty Pal: But we're going to shift gears to another massive topic, which is oral SERDs. In broad strokes, right, this utilization of CDK4/6 inhibitors in the context of HR-positive breast cancer is obviously, you know, a paradigm that's been well established at this point. Where do we sequence in oral SERDs? Where do they fit into this paradigm? Dr. Hope Rugo: Ha! This is a rapidly changing area; we keep changing what we're saying every other minute. And I think that there are three areas of great interest. So one is patients who develop ESR1 mutations that allow constitutive signaling through the estrogen receptor, even when there's not estrogen around, and that is a really important mutation that is subclonal; it develops under the pressure of treatment in about 40 percent of patients. And it doesn't happen when you first walk in the door. And what we've seen is that oral SERDs as single agents are better than standard single-agent endocrine therapy in that setting. The problem that we've had with that approach is that we're now really interested in giving targeted agents with our endocrine therapies, not just in the first-line setting where CDK4/6 inhibitors are our standard of care with survival benefit for ribociclib and, you know, survival benefit in subsets with other CDK4/6 inhibitors, and abemaciclib with a numeric improvement. So we give it first line. The question is, what do you do in the second-line setting? Because of the recent data, we now believe that oral SERDs should be really given with a targeted agent. And some datasets which were recently presented, which I think have helped us with that, have been EMBER-3 and then the most recently evERA BC, or evERA Breast Cancer, that looked at the oral SERD giredestrant with everolimus compared to standard of care endocrine therapy with everolimus, where 100 percent of patients received prior CDK4/6 inhibitor and showed a marked improvement in progression-free survival, including in the subsets of patients with a short response, 6-12 months of prior response to CDK4/6 inhibitor and in those who had a PIK3CA pathway mutation. The thing is that the benefit looks like it's much bigger in the ESR1 mutant population, although response was better, PFS wasn't better in the wild type. So, we're still trying to figure that out. We also saw EMBER-3 with imlunestrant and abemaciclib as a second line. Not everybody had had a prior CDK4/6 inhibitor; they compared it to imlunestrant alone, but still the data was quite striking and seemed to cross the need for ESR1 mutations. And then lastly, we saw data from the single arms of the ELEVATE trial looking at elacestrant with everolimus and abemaciclib and showed these really marked progression-free survival data, even though single-arm, that crossed the mutation status. At least for the everolimus combination, abemaciclib analysis is still to come in the mutated subgroups. But really remarkable PFS, much longer.  Single-agent fulvestrant after CDK4/6 inhibitor AI has a PFS in like the three-month range and in some studies, maybe close to five months. These are all at 10-plus months and really looking very good. And so those questions are, is it ESR1 mutation alone? Is it all comers? We'd like all comers, right? We believe in the combination approach and we're learning more about combinations with drugs like capivasertib and other drugs as we move forward. Everybody now wants to combine their targeted agent with an oral SERD because they're clearly here to stay with quite remarkable data. The other issue, so the second issue in the metastatic setting is, does it make a difference if we change to an oral SERD before radiographic imaging evidence of progression? And that was the question asked in the SERENA-6 trial where patients had serial monitoring for the presence of ESR1 mutations in ctDNA. And those who had them without progression on imaging could be randomized to switch to camizestrant with the same CDK4/6 inhibitor or stay on their same AI CDK4/6 inhibitor. And they showed a difference in progression-free survival that markedly favored camizestrant. But interestingly, the people who were on the standard control arm had an ESR1 mutation, we think AIs don't work, they stayed on for nine more months. The patients who were on the camizestrant stayed on for more than 16 months. And they presented some additional subset data which showed the same thing: follow-up PFS data, PFS2, all beneficial in SERENA-6 at the San Antonio [Breast Cancer Symposium]. So, we're still a little bit unclear about that. They did quality of life, and pain was markedly improved. They had a marked delayed time to progression of pain in the camizestrant arm. So this is all a work in progress, trying to understand who should we switch without progression to an oral SERD based on this development of this mutation that correlates with resistance. And, you know, it's interesting because the median time to having a mutation was 18 months and the median time to switch was almost 24 months. And then there were like more than 3,000 patients who hadn't gotten a mutation, hadn't switched, and were still okay. So screening everybody is the big question, and when you would start and who you would change on and how this affects outcome. Patients didn't have access to camizestrant in the control arm, something we can't fix but we have experimental drugs. We're actually planning a trial, I hope in collaboration with the French group Unicancer, and looking at this exact question. You know, if you switch and you change the CDK4/6 inhibitor and then you also allow crossover, what will we see? Dr. Monty Pal: We're coming right to the tail end of our time here, and I could probably go on for another couple of hours with you here. But if you could just give us maybe one or two big highlights from San Antonio, any thoughts to leave our audience with here based on this recent meeting? Dr. Hope Rugo: Yeah, I mean, I talked about a lot of those new data already from San Antonio, and the one that I'd really like to mention which I think was, you know, there were a lot of great presentations including personalized screening presented from the WISDOM trial by my colleague Laura Esserman, fascinating and really a big advance. But lidERA was the big highlight, I think, outside of the HER2CLIMB-05 which I talked about earlier in HER2-positive disease. And this study looked at giredestrant, the oral SERD versus standard of care endocrine therapy as treatment for medium and high-risk early-stage breast cancer. And what they showed, which I think was really remarkable with just about a three-year median follow-up, was an improvement in invasive disease-free survival with a hazard ratio of 0.7. I mean, really quite remarkable and so early. It looked as though this was all driven by the high-risk group, which makes sense, not the medium risk, it's too early. And also that there was a bigger benefit in patients who were on tamoxifen compared to giredestrant versus AI, but for both groups, the confidence intervals didn't cross 1. There's even a trend towards overall survival, even though it's way too early. I think that, you know, really well-tolerated oral drug that could improve outcome in early-stage disease, this is the first advance we've seen in over two decades in the treatment of early-stage hormone receptor-positive disease with just endocrine therapy. I think we think that we don't want to give up CDK4/6 inhibitors because we saw a survival benefit with abemaciclib and a trend with giving ribociclib in the NATALEE trial. So we're thinking that maybe one approach would be to give CDK4/6 inhibitors and then switch to an oral SERD or to have enough data to be able to give oral SERDs with these CDK4/6 inhibitors for early-stage disease. And that's all in the works, you know, lots of studies going on. We're going to see a lot of data with both switching 8,000 patients with an imlunestrant switching trial, an elacestrant trial going on, and safety data with giredestrant with abemaciclib and soon to come ribociclib. So, this is going to change everything for the treatment of early-stage breast cancer, and I hope cure more patients of the most common subset of the most common cancer diagnosed in women worldwide. Dr. Monty Pal: Super exciting. It's just remarkable to hear how this has evolved since 25 years ago, which is really the last time I sort of dabbled in breast cancer.  Thank you so much, Hope, for joining us today. These were fantastic insights. Appreciate you being on the ASCO Daily News Podcast and really want to thank you personally for your remarkable contribution to the field of breast cancer. Dr. Hope Rugo: Thank you very much, and thanks for talking with me today. Dr. Monty Pal: You got it. And thanks a lot to our listeners today as well. You'll find links to all the studies we discussed today in the transcript of this episode. Finally, if you value the insights that you hear today on the ASCO Daily News Podcast, please rate, review, and subscribe wherever you get your podcasts. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinion of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Follow today's speakers:   Dr. Monty Pal @montypal Dr. Hope Rugo   @hoperugo Follow ASCO on social media:        ASCO on X  ASCO on Bluesky       ASCO on Facebook        ASCO on LinkedIn        Disclosures:     Dr. Monty Pal:    Speakers' Bureau: MJH Life Sciences, IntrisiQ, Peerview   Research Funding (Inst.): Exelixis, Merck, Osel, Genentech, Crispr Therapeutics, Adicet Bio, ArsenalBio, Xencor, Miyarsian Pharmaceutical   Travel, Accommodations, Expenses: Crispr Therapeutics, Ipsen, Exelixis   Dr. Hope Rugo:    Honoraria: Mylan/Viatris, Chugai Pharma   Consulting/Advisory Role: Napo Pharmaceuticals, Sanofi, Bristol Myer   Research Funding (Inst.): OBI Pharma, Pfizer, Novartis, Lilly, Merck, Daiichi Sankyo, AstraZeneca, Gilead Sciences, Hoffman La-Roche AG/Genentech, In., Stemline Therapeutics, Ambryx  

Ce jeudi 8 janvier, François Sorel a reçu Bruno Guglielminetti, journaliste et animateur de "Mon Carnet de l'actualité numérique", et Jérôme Colombain, journaliste et créateur du podcast « Monde Numérique ». Ils se sont penchés sur la grande présence de la Chine pendant la CES 2026, la présentation du SUV électrique de Sony et Honda, les démonstrations sur la voiture autonome pendant la CES 2026, la présentation des produits de Lenovo à la Sphère, le nouveau clavier de HP, l'utilisation de la technologie au service de l'inclusion, ainsi que le cadre photo dopé à l'IA qui donne vie aux images, dans l'émission Tech & Co, la quotidienne, sur BFM Business. Retrouvez l'émission du lundi au jeudi et réécoutez la en podcast.

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

Listen to a recap of the top stories of the day from 9to5Mac. 9to5Mac Daily is available on iTunes and Apple's Podcasts app, Stitcher, TuneIn, Google Play, or through our dedicated RSS feed for Overcast and other podcast players. Sponsored by 9to5Mac Daily Plus: Get ad-free versions of every episode by visiting 9to5mac.com/join.  New episodes of 9to5Mac Daily are recorded every weekday. Subscribe to our podcast in Apple Podcast or your favorite podcast player to guarantee new episodes are delivered as soon as they're available. Stories discussed in this episode: iPadOS 26.2 and macOS 26.2 unlock faster Wi-Fi on select devices Dell, HP, and Lenovo opposing Apple trend with new laptop designs Leaker suggests future iPhones could get multispectral cameras New iPhone with 200MP camera gets release timing update Listen & Subscribe: Apple Podcasts Overcast RSS Spotify TuneIn Google Podcasts Subscribe to support Chance directly with 9to5Mac Daily Plus and unlock: Ad-free versions of every episode Bonus content Catch up on 9to5Mac Daily episodes! Don't miss out on our other daily podcasts: Quick Charge 9to5Toys Daily Share your thoughts! Drop us a line at happyhour@9to5mac.com. You can also rate us in Apple Podcasts or recommend us in Overcast to help more people discover the show.

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

PC makers are shaking up CES with wild designs and next-gen chips, but the real story is Microsoft's bold software moves, AI's hardware hunger, and a candid debate over whether any tech company still puts users first. Come for the Windows updates, stay for the whisky warnings and robot bathroom assistants. CES 2026 is here with the 4K hummingbird feeder of your dreams New PCs and more from HP consumers/commercial, HP gamers, Lenovo, others The first official Copilot+ PC desktops Snapdragon X2 Plus joins X2 Elite and X2 Elite Extreme Intel Panther Lake has meaningful CPU and graphics performance gains, but predictable reliability issues AMD Ryzen AI 400 series is a minor bump Windows Paul was the first to report that Microsoft is refactoring it all with Rust A Microsoft distinguished engineer wrote about his desire to refactor all C/C++ code in the company with Rust by 2030 Some mistook this to mean "rewriting Windows with Rust,ˮ so he had to issue a clarification. But I never wrote that. Heads-up: That will happen, but this is really about Azure first and the core underlying code in Microsoftʼs most important platforms Microsoft released hardware-accelerated BitLocker in late 2025 and never told anyone. It requires the latest PC CPUs Copilot app update that adds text editing actions to Copilot Vision across channels Dev and Beta got first previews of AI agents on the Taskbar, starting with the Researcher agent, plus underlying Agent Launchers experience IDC says the global memory shortage (thanks, AI!) could screw up PC and smartphone growth this year AI ChatGPT now has an app store, but it has a ways to go Mozilla Firefox will have a "killswitchˮ for AI Our national nightmare will soon be over, LG will let users remove Copilot app from their smart TVs Xbox and gaming First Xbox Game Pass releases of 2026 include Resident Evil Village and Star Wars Outlaws Xbox Cloud Gaming is coming to Hisense smart TVs and to the latest Fire TV smart TVs GOG goes independent, will continue DRM-free push "Have a blastˮ and other FPS throwbacks from the 1990s Valve quietly killed the LCD Steam Deck model Tips and picks Tip of the week: Itʼs time to give Little AI a look App pick of the week: Bonjourr RunAs Radio this week: What AI can do for SysAdmins in 2026 with Cecilia Wiren Brown liquor pick of the week: The Singleton of Dufftown 12 Hosts: Leo Laporte, Paul Thurrott, and Richard Campbell Download or subscribe to Windows Weekly at https://twit.tv/shows/windows-weekly Check out Paul's blog at thurrott.com The Windows Weekly theme music is courtesy of Carl Franklin. Join Club TWiT for Ad-Free Podcasts! Support what you love and get ad-free audio and video feeds, a members-only Discord, and exclusive content. Join today: https://twit.tv/clubtwit Sponsors: threatlocker.com/twit cachefly.com/twit

Discover the latest accessible tech trends from CES 2026, including HP's groundbreaking EliteBoard G1 keyboard PC, Dell's refreshed XPS laptops, and the growing challenges of RAM shortages caused by AI demand. Steven Scott and Shaun Preece discuss how these innovations impact blind users, why some “accessible” products miss the mark, and the surprising rise of computer-in-a-keyboard devices.In this Double Tap episode, Steven and Shaun break down the biggest headlines from CES in Las Vegas. They explore HP's EliteBoard G1, a full PC built into a keyboard, and discuss why it could be a game-changer for blind users looking for portable, all-in-one solutions. The conversation also covers Dell's XPS revival with physical function keys, the looming PC price hikes due to RAM shortages, and the growing demand for AI-ready devices. The hosts also critique accessibility in mainstream tech, highlighting frustrations with Elgato and RØDE software and the difference between intentional and accidental accessibility. Listener emails bring personal stories about guide dog training, BitLocker workarounds, and voice assistant tips for iPhone and Android.Enjoying Double Tap? Subscribe for more accessible tech discussions, share your feedback at feedback@doubletaponair.com, and join the conversation on making mainstream tech work for everyone.Relevant LinksCES Official Site: https://www.ces.tech Find Double Tap online: YouTube, Double Tap Website---Follow on:YouTube: https://www.doubletaponair.com/youtubeX (formerly Twitter): https://www.doubletaponair.com/xInstagram: https://www.doubletaponair.com/instagramTikTok: https://www.doubletaponair.com/tiktokThreads: https://www.doubletaponair.com/threadsFacebook: https://www.doubletaponair.com/facebookLinkedIn: https://www.doubletaponair.com/linkedin Subscribe to the Podcast:Apple: https://www.doubletaponair.com/appleSpotify: https://www.doubletaponair.com/spotifyRSS: https://www.doubletaponair.com/podcastiHeadRadio: https://www.doubletaponair.com/iheart About Double TapHosted by the insightful duo, Steven Scott and Shaun Preece, Double Tap is a treasure trove of information for anyone who's blind or partially sighted and has a passion for tech. Steven and Shaun not only demystify tech, but they also regularly feature interviews and welcome guests from the community, fostering an interactive and engaging environment. Tune in every day of the week, and you'll discover how technology can seamlessly integrate into your life, enhancing daily tasks and experiences, even if your sight is limited. "Double Tap" is a registered trademark of Double Tap Productions Inc. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

出演者： miko、quim 配信ペース： 隔週水曜日 番組時間：95分20秒 ♯本番組はリモート収録です。 ♯収録時環境の影響により、全体的に聴き取り辛くなっております。 　申し訳ございません。 てん、てててててててん… かがみもー。2026年もマイペースなmikoラジ、第388回です。 毎年恒例、春の海チャレンジからスタートする2026年1回目。 大晦日まで働いた我さんと、しっかり連休をとったしがないさんの噛合わない年末年始。 何だかんだで、それなりご長寿番組になっても変わらぬお家れでぃお。 最後までごゆるりとお楽しみくださいませ。 ♯途中で色々とノイズ等入りますが、収録時のものです。 　ご安心ください、お手持ちの機器は正常です。 //////////////////// VOICEVOX:ずんだもん VOICEVOX:四国めたん //////////////////// -------------------- ●お便り募集中！ mikoラジでは以下の内容でお便りを募集中です！ ・ふつおた 　／普通のお便り、お待ちしています！ ・mikoは大変な絵を描いていきました 　／miko画伯に描いて欲しいお題をお待ちしています！ ・メシヲコエテ 　／料理人・mikoに教えて欲しいレシピをお待ちしています！ bit.ly/2GAWjyv 投稿フォームからラジオに投稿が出来ます！ コーナー名を選び、メッセージ・ラジオネーム・お所を入力して、 どんどん送ってください！　お待ちしています！！ ------------ 本ラジオのメインパーソナリティーである「チーム我等(miko/quim)」、 それぞれ以下個人サークルにて活動中です。 ・miko：miko ・quim：SHIGANAI RECORDS（ shiganai.com/ ） 活動詳細については、上記HPの他 各人のブログ/twitter等にて随時告知しておりますので、チェックしてみてください！ ・みころぐ。(mikoのブログ)（ ameblo.jp/miko-nyu/ ） ・@ mikonyu(mikoのtwitter)（ twitter.com/mikonyu ） ・@ quim(quimのtwitter)（ twitter.com/quim ） --- その他の活動については、以下のとおりです！ -- チーム我等がメインクルーとして活動していた「アルバトロシクス（ albatrosicks.com/ ）」、 これまでリリースしたCDは、イオシスショップ（ iosys.booth.pm/ ）にて頒布しております。ご興味ある方は是非！ ---------- ☆2025年1月IOSYSはいてない.comパワープレイ楽曲 M1. YATSUZAKI HARDCORE (Liqo NEXT100 Remix) 作曲：SHC crew リミックス：Liqo 音楽ジャンル：Hardcore 収録アルバム：YATSUZAKI HARDCORE COLLECTION 2025 2025・12・31 Release https://notebookrecords.net/discographyportal.php?cdno=YHC-1005 変わらぬ"やりたい音"を、札幌から全世界へ！ YATSUZAKI HARDCOREが贈る2025年総まとめコンピレーション！

#318 | Dave is joined by Kieran Flanagan, SVP of Marketing at HubSpot and former CMO at Zapier. They break down how AI is reshaping B2B marketing workflows, content creation, and team structure, plus Kieran's leadership philosophy for managing a 300+ person team while staying deeply involved in creative execution. This episode offers a clear look at how AI is changing the game and how B2B marketers can stay creative, strategic, and indispensable in the process.Timestamps(00:00) - – Intro + why AI matters now (04:28) - – Kieran's career + the 2-year mission framework (09:58) - – The grind, early-career advice, and earning your stripes (12:28) - – Operator vs. manager + strong opinions in leadership (20:28) - – Why collaborative brainstorms fail (25:28) - – ChatGPT vs. Claude + how Kieran actually uses AI (33:16) - – Where AI is taking B2B marketing (answers → actions) (44:46) - – Picking a lane: technical vs. creative marketers (52:16) - – The future CMO + agencies, in-person, and what still matters Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

Bernadette P is from New Jersey and she is sharing at the Fellowship of the Spirit on Step 11, specifically on the topic -  The purpose of meditation is to improve our conscious contact with HP's grace and wisdom. Recorded in May 2022. Zoom Support Sober Cast: https://sobercast.com/donate Email: sobercast@gmail.com Sober Cast has 3000+ episodes available, visit SoberCast.com to access all the episodes where you can easily find topics or specific speakers using tags or search. https://sobercast.com

Book 7, Chapter 2: In Memoriam

#317 | Dave hosts a live session with Dasha Shakov (Head of Marketing, Proton.ai), Emeric Ernoult (Founder, CEO, Agorapulse), and Finn Thormeier (Founder, Project 33) to break down what's working on LinkedIn right now. They discuss why LinkedIn is the most important channel for B2B, why social media is the best marketing channel available today, how founder-led and employee content drives growth, and what's changed about how people use the platform over the last five years. The group also gets into LinkedIn's thought leader ads, thoughts on measuring results when attribution is messy, and how to sell LinkedIn's value to leadership and convince them to spend time there. It's a look into how B2B teams can earn attention, build credibility, and make LinkedIn a massive growth channel in 2026.Timestamps(00:56) - – Why LinkedIn is still Dave's favorite B2B channel (05:01) - – Panel intros: Dasha, Finn, Emeric (07:25) - – Why LinkedIn changed and why it matters now (09:34) - – “Our buyers aren't on LinkedIn” is mostly wrong (12:26) - – Who should post: CEO, team, or company page (16:47) - – Why promo posts flop (and why that's okay) (21:44) - – What to actually post when starting from zero (38:13) - – Why thought leader ads outperform everything else Join 50,0000 people who get Dave's Newsletter here: https://www.exitfive.com/newsletterLearn more about Exit Five's private marketing community: https://www.exitfive.com/***Brought to you by:Optimizely - A no-code AI platform where autonomous agents execute marketing work across webpages, email, SEO, and campaigns. Get a free, personalized 45-minute AI workshop to help you identify the best AI use cases for your marketing team and map out where agents can save you time at optimizely.com/exitfive. AirOps - The content engineering platform that helps marketers create and maintain high-quality, on-brand content that wins AI search. Go to airops.com/exitfive to start creating content that reflects your expertise, stays true to your brand, and is engineered for performance across human and AI discovery.Visit exitfive.com/retreat to apply for Exit Five's first-ever, in-person Marketing Leadership Retreat, March 18–20, 2026 in Scottsdale, Arizona. Join 100 CMOs and VPs of Marketing from companies like like Zoom, Snowflake, Manychat, Bitly, G2, HP, and more for two days of thinking bigger around a trusted group of peers in marketing. ***Thanks to my friends at hatch.fm for producing this episode and handling all of the Exit Five podcast production.They give you unlimited podcast editing and strategy for your B2B podcast.Get unlimited podcast editing and on-demand strategy for one low monthly cost. Just upload your episode, and they take care of the rest.Visit hatch.fm to learn more

In this episode, Tracy chats with Flora Munro, Head of Events, Scotland at 2B UK, live from the IMEX America show floor to explore how Scotland's hospitality, food, and culture create unforgettable event experiences. From castle-sourced venison and hand-dived scallops cooked straight from the sea to whisky tastings (and a spirited debate about haggis and HP "brown" sauce), Flora shares how Scottish culinary traditions are being reimagined for modern meetings and incentives. They also discuss how Scotland leads with inclusion—where accommodating dietary needs is second nature—and sustainability, with menus planned months in advance and ingredients locally sourced to minimize waste and celebrate the land's abundance. Whether you're planning your next incentive trip or dreaming of dining with a view of Edinburgh's Royal Botanic Garden, this episode is a delicious reminder that in Scotland, every meal tells a story—and, as Flora says, "every meal should be devoured."

Weird Westerns - Complete  Audiobook - The West wasn't just wild. It was weird. Journey into a twisted frontier where Jonah Hex meets H.P. Lovecraft, a land of grizzled gunslingers and cosmic dread. In these tales of weird western horror, the silence of the prairie is not empty, and the greatest threat isn't a bullet in the back, but a truth that can unmake a man's mind. From rocks that bleed impossible colors to telegraphs that receive messages from the void, prepare to discover the stories the official histories were too terrified to write. This is STEVE STOCKTON'S WHEN THE WEST WAS WEIRD.Become a supporter of this podcast: https://www.spreaker.com/podcast/missing-persons-mysteries--5624803/support.

Episode #115 of the Whitening Wednesday Podcast, the only teeth whitening podcast

※一部音声が聴き取りにくくなっております。ご了承ください。 出演者：藤原鞠菜 配信ペース：隔週火曜日 番組時間：平均40分 ——————————————————————— ＜各テーマ紹介＞配信されるテーマは回によって異なります。 「ふつおた」･･･何でもありのお便りコーナー。投稿は毎日募集中！！！！！ 「歴史秘話ウィステリア」･･･サークル曲の裏話など。 「まりにゃのこれな～んだ？」･･･音当てクイズ。 「まりにゃのオススメ」･･･オススメ商品をご紹介。 「はじおと」･･･「音楽」×「初めて」に関して語るコーナー。 （初めて買ったCD、初めて心を動かされた音楽、初めてカラオケで歌った曲等。） 「これかた」･･･テーマを決めて語る割とフリーダムなコーナー。 （テーマや語ってみた投稿募集中。） 「答えて、まりにゃ」･･･まりにゃへの質問募集中。 「トレンドなう」･･･収録時に開いたTwitterのリアルタイムトレンドについてコメント。 「まりにゃのTOP5」･･･思いついたら勝手にランキング。 「まりにゃのドキドキ質問箱」…twitter投稿になります。（ https://peing.net/marinya_）  「みんなの答え合わせ」…twitterで出題するアンケートの結果報告。みんなに聞きたいこと募集中。 ——————————————————————— ——————————————————————— ■CD新作・出演告知など■ ★Wisteria Magic通販サイト「うぃすましょっぷ」★ wismashop.booth.pm/ 新作も旧作も全て送料込み！ ★イオシスショップ様にて一部旧作を委託販売中！★ www.iosysshop.com/SHOP/list.php?Search=wisteria ★しがないレコーズのyoutube「しがない5分ショー」に出演してます。 藤原鞠菜は木曜日担当です。 https://www.youtube.com/channel/UCA_FmkoMu24R_6o3m3_Ulqg —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ・の〜すとらいく様の18禁PCゲーム 「女装百合畑/Trap Yuri Garden」にて、主題歌「優雅にヒロイン宣言」を担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして！夜までもっとエッチして！」 にて女未こはくちゃん(三女)のED曲担当させて頂きました。 ・TinklePosition様の18禁PCゲーム 「お兄ちゃん、朝までずっとギュッてして!」 にて女未こはくちゃん(三女)のED曲を担当させて頂きました。 —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– —–　　—–　　—–　　—–　　—–　　—–　　—–　　—– ——————————————————————— この番組は音楽サークルWisteria Magicがお届けする番組です。 藤原鞠菜やサークルの過去または最新の活動内容につきましては 以下をチェックしてくださると嬉しいです♪ ・藤原鞠菜のTwitter（ twitter.com/marinya_ ） ・藤原鞠菜のHP「ふじわらんど」（ fujimari.com/ ） ・磯村カイのTwitter（ twitter.com/isomurakai ） ・磯村カイのHP「TONAKAI soundworks」（ https://soundworks.tonakaii.com/ ） 藤原鞠菜への贈り物の宛先 〒107-0052 東京都港区赤坂4-9-25 新東洋赤坂ビル10F レイズイン　アカデミー気付　藤原鞠菜宛 VOICEVOX:ずんだもん VOICEVOX:四国めたん

Un épisode à écouter en plein Dry January, pour comprendre ce que l'alcool dit de nous, et ce qu'on peut faire sans lui.  Il débarque comme un apéro sans fin, un gueulard attachant, amateur de bœuf bourguignon et de vin qui tâche. Mais sous le rire bleu métal et les punchlines gras-double, il y a un mec qui boit pour éteindre les secousses intérieures. A 14 ans, il savait déjà ! L'alcool avait choisi pour lui. Virer pour une vidéo, propulser humoriste malgré lui, il a touché le fond entre deux Zénith. Rechute, mensonge, HP, diagnostic: bipolaire. Et puis un jour, il a décidé d'essayer la vie sans filtre. La vie tout court. Chicandier, c'est l'histoire d'un type qui n'est pas passé de bon vivant à végan, mais de survivant à vivant... point.Rendez-vous jeudi sur toutes les plateformes de podcast, Youtube et les réseaux sociaux de Rose et de Contre-addictions.

出演者： miko、quim 配信ペース： 隔週水曜日（都合により配信遅延いたしました） 番組時間：87分35秒 ♯本番組はリモート収録です。 ♯収録時環境の影響により、全体的に聴き取り辛くなっております。 　申し訳ございません。 2025年も終わりですね……mikoラジ第387回です。 遅延したりなんだり色々とありましたが、今年も無事にmikoラジ納めです。 メリクリ&ハッピーニューイヤー！ 2026年もよろしくお願いしまーす！ https://youtu.be/woZexUQ6MuA?si=NLV-53kfAdF00Qhe ♯途中で色々とノイズ等入りますが、収録時のものです。 　ご安心ください、お手持ちの機器は正常です。 //////////////////// VOICEVOX:ずんだもん VOICEVOX:四国めたん //////////////////// -------------------- ●お便り募集中！ mikoラジでは以下の内容でお便りを募集中です！ ・ふつおた 　／普通のお便り、お待ちしています！ ・mikoは大変な絵を描いていきました 　／miko画伯に描いて欲しいお題をお待ちしています！ ・メシヲコエテ 　／料理人・mikoに教えて欲しいレシピをお待ちしています！ bit.ly/2GAWjyv 投稿フォームからラジオに投稿が出来ます！ コーナー名を選び、メッセージ・ラジオネーム・お所を入力して、 どんどん送ってください！　お待ちしています！！ ------------ 本ラジオのメインパーソナリティーである「チーム我等(miko/quim)」、 それぞれ以下個人サークルにて活動中です。 ・miko：miko ・quim：SHIGANAI RECORDS（ shiganai.com/ ） 活動詳細については、上記HPの他 各人のブログ/twitter等にて随時告知しておりますので、チェックしてみてください！ ・みころぐ。(mikoのブログ)（ ameblo.jp/miko-nyu/ ） ・@ mikonyu(mikoのtwitter)（ twitter.com/mikonyu ） ・@ quim(quimのtwitter)（ twitter.com/quim ） --- その他の活動については、以下のとおりです！ -- チーム我等がメインクルーとして活動していた「アルバトロシクス（ albatrosicks.com/ ）」、 これまでリリースしたCDは、イオシスショップ（ iosys.booth.pm/ ）にて頒布しております。ご興味ある方は是非！ ---------- ☆2025年12月IOSYSはいてない.comパワープレイ楽曲 M3. Critikal & RoughSkreamZ - 89seconds Death Ride 作曲：Critikal 編曲：Critikal & RoughSkreamZ 音楽ジャンル：Uptempo Hardcore Metal 収録アルバム：Critikal Distorxion EP 2025・10・26 Release https://notebookrecords.net/discographyportal.php?cdno=NBCD-051 Liqoの変名義「Critikal(クリティカル)」による1st EP。 Uptempo Hardcore/Metal/Happy Hardcoreを飲み込んだ爆速の攻撃的サウンド。 RoughSkreamZとのコラボ楽曲、さらにRoughSketchによるリミックスを含む、全5曲収録。

In this episode I'm going to do something a little different. As we wind down for the year, we're going to be running some of our favorites from 2025 until the new year begins.Let's take a look back at some of the overall themes discussed and point out a few highlights for me. I won't be able to highlight everything of course but I found 5 themes really interesting. And, I won't lie - I had a little help from AI in doing this. But that's also kind of the point. We have all been using AI to do things to make our work easier, and I thought that poring through 150+ episodes recorded over 12 months is a perfect thing to have AI help me with. About Greg Kihlström Greg Kihlström is a best-selling author, speaker, and entrepreneur, and serves as an advisor and consultant to top companies on marketing technology, marketing operations, and digital transformation initiatives. He has worked with some of the world's top brands, including Adidas, Coca-Cola, FedEx, HP, Marriott, Nationwide Insurance, Victoria's Secret, and Toyota. He is a multiple-time Co-Founder and C-level leader, leading his digital experience agency to be acquired in 2017, successfully exited an HR technology platform provider he co-founded in 2020, and led a SaaS startup to be acquired by a leading edge computing company in 2021. He currently advises and sits on the Board of a marketing technology startup.In addition to his experience as an entrepreneur and leader, he earned his MBA, is currently a doctoral candidate for a DBA in Business Intelligence, and teaches several courses and workshops as a member of the School of Marketing Faculty at the Association of National Advertisers. He has served on the Virginia Tech Pamplin College of Business Marketing Mentorship Advisory Board, the University of Richmond's CX Advisory Board, and was the founding Chair of the American Advertising Federation's National Innovation Committee.  Greg is Lean Six Sigma Black Belt certified, is an Agile Certified Coach (ICP-ACC), and holds a certification in Business Agility (ICP-BAF).  Greg Kihlström on LinkedIn: https://www.linkedin.com/in/gregkihlstrom Resources The Agile Brand Podcast: https://www.gregkihlstrom.com The Agile Brand podcast is brought to you by TEKsystems. Learn more here: https://www.teksystems.com/versionnextnow Catch the future of e-commerce at eTail Palm Springs, Feb 23-26 in Palm Springs, CA. Go here for more details: https://etailwest.wbresearch.com/ Enjoyed the show? Tell us more at and give us a rating so others can find the show at: https://ratethispodcast.com/agileConnect with Greg on LinkedIn: https://www.linkedin.com/in/gregkihlstromDon't miss a thing: get the latest episodes, sign up for our newsletter and more: https://www.theagilebrand.showCheck out The Agile Brand Guide website with articles, insights, and Martechipedia, the wiki for marketing technology: https://www.agilebrandguide.com The Agile Brand is produced by Missing Link—a Latina-owned strategy-driven, creatively fueled production co-op. From ideation to creation, they craft human connections through intelligent, engaging and informative content. https://www.missinglink.company

HP: https://www.youtube.com/@theeuropeanconservative https://www.restorebritain.org.uk/ https://x.com/Harry_pitt J: https://findmyfrens.net/jburden/ Buy me a coffee: https://www.buymeacoffee.com/j.burden Substack: https://substack.com/@jburden Patreon: https://patreon.com/Jburden GUMROAD: https://radiofreechicago.gumroad.com/l/ucduc Axios: https://axios-remote-fitness-coaching.kit.com/affiliate ETH: 0xB06aF86d23B9304818729abfe02c07513e68Cb70 BTC: 33xLknSCeXFkpFsXRRMqYjGu43x14X1iEt

This week we make a few end-of-year predictions for what 2026 will hold in store for Harry Potter fans, and open up the MuggleMail bag further than ever, as we read recent comments from YouTube and Spotify in addition to Discord, voicemails and e-mail! Join Andrew, Eric, Micah and Laura for our final episode of 2025! Looking ahead: what news will we get about a Hogwarts Legacy sequel? How about the HBO TV series? Will more series be green lit? Andrew leads the group in making unhinged predictions including genderbent books and a line of adults-only official merchandise. Our own 2026 plans for MuggleCast include content that looks ahead as well as back, including more talks on the TV show and classic components of HP fandom history. Voicemails sent in include a Hermione Granger impression, and ask the question, "how do children learn Voldemort's name?" Was Arthur Weasley's originally-planned death hinted at in the text of Book 5 and before? Spotify listeners want to know: is Snape projecting? What is the general skill level of your average every day wizard? And will Micah tell more dad jokes? Is Severus Snape a good teacher? What about his old Potions book? Why doesn't Dumbledore ever tell Harry exactly how to destroy the Horcruxes? And, does Hermione belong in Ravenclaw? Additionally, folks tell us their feelings on the Full Cast Harry Potter Audiobooks as well as the Tonks and Lupin romantic subplot. Our Lynx Line segment asks our most dedicated listeners for recommendations of books they've read this year and enjoyed. See the full list of suggestions here! Bonus MuggleCast, available over on our Patreon, will have the hosts discussing their behind-the-scenes stories of contributing to MuggleNet.com MuggleCast will return January 12, 2026! Learn more about your ad choices. Visit megaphone.fm/adchoices

Hear from Paul Spain and Ben O'Brien as they unpack the latest tech news including NZ Police's redaction glitch, a new Government Digital Delivery Agency, smart TV privacy concerns, James Powell's transition from Dawn Aerospace and Waymo's outage pause and the future of autonomous vehicles. Plus, Ben O'Brien shares insights from his upcoming book for founders. A must-listen for tech enthusiasts and entrepreneurs!We'd love to get your feedback, please fill in our short survey and go into the draw for some great tech giveaways. Audience Survey - December 2025 - NZ Tech PodcastThanks to our Partners One NZ, Workday, 2degrees, HP, Spark and Gorilla Technology

Positive trends related to public IP range from the year 2025 Fewer ICS systems, as well as fewer systems with outdated SSL versions, are exposed to the internet than before. The trend isn t quite clean for ISC, but SSL2 and SSL3 systems have been cut down by about half. https://isc.sans.edu/diary/Positive%20trends%20related%20to%20public%20IP%20ranges%20from%20the%20year%202025/32584 Hewlett-Packard Enterprise OneView Software, Remote Code Execution HPs OneView Software allows for unauthenticated code execution https://support.hpe.com/hpesc/public/docDisplay?docId=hpesbgn04985en_us&docLocale=en_US#vulnerability-summary-1 Trufflehog Detecting JWTs with Public Keys Trufflehog added the ability to detect JWT tokens and validate them using public keys. https://trufflesecurity.com/blog/trufflehog-now-detects-jwts-with-public-key-signatures-and-verifies-them-for-liveness

Crystal-clear water means more than fine micron ratings; it means steady flow, low pressure spikes, and a filter you can actually live with. We dive into the real-world reasons cartridge filters outperform DE and sand for most pools, from massive surface area that keeps PSI stable to a simple cleaning routine that skips the gray dust and regulatory headaches of diatomaceous earth.We walk through how pleated media provides 7x the surface area of common DE setups, why that matters for circulation, and how stable flow prevents dead zones, improves skimming, and reduces algae risk. You'll hear practical comparisons: DE at 3–5 microns, cartridge around 10–20, sand near 40—and why your eye won't notice the difference between 5 and 15 microns, but your spa spillway will notice the flow. We also cover where sand or DE still makes sense, especially in high-dust regions where backwashing is a lifeline, and for homeowners who need the simplest possible maintenance routine.If you run a variable speed pump, this conversation is a must. Cartridges pair naturally with higher throughput, keeping performance consistent at elevated speeds and making the most of modern 3 HP total-rated motors. We break down service realities—DE recharging, grid tears, cracked manifolds, and messy burps—versus the straightforward hose-and-go workflow of cartridges. Then we talk replacement cycles, brand recommendations for elements, and why most new builds default to cartridges because of both performance and local DE disposal rules.• Why cartridge surface area preserves flow and reduces PSI rise• Micron ratings vs what the human eye can see• When high-dirt regions may favor sand or DE• Variable speed pump compatibility and throughput• Cleaning workflows and mess: DE recharging vs quick cartridge rinse• Common failure points in DE and sand that cartridges avoid• Cost and replacement cycles for grids vs cartridges• Sizing guidance using 420–520 sq ft examples• Builder trends and local DE disposal rulesSend us a textSupport the Pool Guy Podcast Show Sponsors! HASA https://bit.ly/HASAThe Bottom Feeder. Save $100 with Code: DVB100https://store.thebottomfeeder.com/Try Skimmer FREE for 30 days:https://getskimmer.com/poolguy Get UPA Liability Insurance $64 a month! https://forms.gle/F9YoTWNQ8WnvT4QBAPool Guy Coaching: https://bit.ly/40wFE6y

How does a serial entrepreneur navigate the ever-evolving tech landscape? In this conversation with Mike Armistead, co-founder and CEO of Pulse Security AI, Cam and Otis explore the art of building companies that endure beyond short-term trends."Leadership is about matching strategies to people and situations," Mike explains, drawing from his extensive experience in founding and growing technology companies. From his early days at Pure Software and Lycos to co-founding Fortify Software and Respond Software, Mike shares insights into the critical role of timing, persistence, and adaptability in entrepreneurial success.What makes this episode particularly valuable is Mike's focus on the intersection of technology and business strategy. "The next major shift is artificial intelligence," he notes, discussing how Pulse Security AI is bridging the gap between technical security tools and broader business objectives. Whether you're an aspiring entrepreneur, a tech enthusiast, or a leader looking to align strategies with people, Mike's journey offers a roadmap for navigating complex challenges with clarity and purpose.More About Mike:Mike Armistead is a serial entrepreneur and corporate leader who has built and grown technology companies for more than thirty years. His career began at Pure Software, Reed Hastings' first startup before Netflix, and later at Lycos during the early internet boom. He went on to co-found Fortify Software, which grew into a category leader before being acquired by HP. Mike then co-founded Respond Software, which was acquired by FireEye for $186 million in 2020. When FireEye split into Mandiant and later became part of Google, he continued to focus on the next major shift in technology: artificial intelligence. Today, Mike is the co-founder and CEO of Pulse Security AI, where he helps organizations close the gap between technical security tools and the broader business strategies they are meant to support. A Stanford-educated engineer, he has also coached more than 500 youth sportsgames, an experience that shaped his belief that leadership is about matching strategies to people and situations. His career reflects persistence, timing, and a commitment to building companies that last beyond short-term trends.#10xyourteam #EntrepreneurialLeadership #TechLeadership #SerialEntrepreneur #BusinessStrategy #ArtificialIntelligence #AILeadership #ScalingCompanies #StartupJourney #TechInnovation #LeadershipMindsetChapter Times and Titles:From Pure Software to Lycos [00:00 - 10:00]Introduction to Mike ArmisteadEarly career at Pure Software and LycosLessons from the early internet boomCo-Founding Fortify Software [10:01 - 20:00]Building a category leader in software securityThe journey to acquisition by HPKey takeaways from scaling a tech companyRespond Software and the FireEye Acquisition [20:01 - 30:00]Co-founding Respond SoftwareThe $186 million acquisition by FireEyeNavigating the acquisition processThe Next Major Shift: Artificial Intelligence [30:01 - 40:00]Founding Pulse Security AIBridging the gap between tech tools and business strategyThe role of AI in future technology trendsLeadership Lessons from Youth Sports [40:01 - 50:00]Coaching over 500 youth sports gamesHow sports shaped Mike's leadership philosophyMatching strategies to people and situationsBuilding Companies That Last [50:01 - End]Persistence and timing in entrepreneurshipFinal thoughts on enduring business successHow to connect with Mike and Pulse Security AIMike Armistead,https://www.linkedin.com/in/mike-armistead-1164715/https://www.linkedin.com/company/pulse-security-ai-inc/https://pulsesecurity.ai/

In this replay from the Kindness Matters series, Kristine Carlson sits down with global leadership expert, humanitarian, and #1 bestselling author Robin Sharma for a heartfelt, wisdom-rich conversation on why kindness is foundational to life mastery, leadership, and meaningful success.    You'll learn: the unforgettable story of Robin meeting Richard Carlson, and the last words Richard shared how relationships, service, and generosity fuel success and build great companies Robin's learning framework, The Four Interior Empires of Mindset, Heartset, Healthset, and Soulset which strengthens our inner foundation so we show up as our best self This inspiring conversation reminds us that kindness is not only who we are at our best—it's what elevates every area of our lives.   Guest bio: Robin Sharma is a globally respected humanitarian who, for over a quarter of a century, has been devoted to helping human beings realize their native gifts. Widely considered one of the top leadership and personal mastery experts and speakers in the world, his clients include NASA, Microsoft, Nike, Unilever, General Electric, FedEx, HP, Starbucks, Oracle, Yale University, PwC, IBM Watson, and the Young Presidents' Organization. As a presenter, Robin Sharma possesses the rare ability to electrify an audience while delivering uncommonly original and tactical insights that lead to individuals doing their best work, teams providing superb results and organizations becoming unbeatable. His #1 international bestsellers such as The 5AM Club, The Wealth Money Can't Buy, The Everyday Hero Manifesto, The Monk Who Sold His Ferrari, and Who Will Cry When You Die? have sold 25+million copies in over ninety-two languages and dialects; making him one of the most widely read authors in the world.    As a special thank you to our listeners, please visit www.kristinecarlson.com/kindness for a free download of an invigorating guided meditation by Kristine—an exclusive sneak peek of her Guided Meditation Series releasing soon.  

Mer de Sicile, août 2024. Un super-yacht nommé Bayesian navigue dans la nuit quand une cellule orageuse éclate à l'horizon. À bord, Mike Lynch, le « Bill Gates britannique », qui vient tout juste de sortir d'un long bras de fer judiciaire avec les États-Unis. Quelques heures plus tard, le silence. Un naufrage éclair, qui soulève plus de questions qu'il n'apporte de réponses.Pour comprendre comment on s'est rendu là, on remonte la trajectoire d'un génie façonné par Cambridge, pis par une obsession : le théorème de Bayes. De Cambridge Neurodynamics à Autonomy, des négos avec HP aux débuts de Darktrace, Lynch a bâti des machines capables de faire parler le chaos : courriels, images, empreintes, signaux faibles. Entre l'État, le renseignement pis le monde des affaires, il a navigué dans une zone grise où les algorithmes ont parfois plus de poids que les mots. C'est ça, notre angle Distorsion : des histoires étranges de l'ère numérique, là où la donnée finit par ressembler à un destin.Au cœur de l'épisode, il y a une séquence troublante de 48 heures, une tempête « statistiquement improbable », pis une enquête italienne qui hésite entre météo extrême, négligence humaine… et d'autres pistes que certains aimeraient peut-être mieux pas trop brasser. Accident, opération discrète ou juste une bad luck poussée au maximum? On recolle les morceaux sans virer complotiste, on écoute les témoins, on suit les chiffres… pis on laisse une place à ce frisson qu'aucun modèle peut vraiment prévoir. Bonne écoute.Découvrez l'exposition immersive Sherlock Holmes : Menez l'enquête présentée par Pointe-à-Callière à Montréal ! Achetez vos billets dès maintenant juste ici : https://bit.ly/expo-distorsionnordvpn.com/distorsion, Rabais exclusif sur ton abonnement + plus 4 mois gratuits! ÉrosEt Compagnie : 15% de rabais avec le code DistorsionPatreonSite WebBoutique Hébergé par Acast. Visitez acast.com/privacy pour plus d'informations.

Send us a textIn this episode, we discuss Netflix acquiring HBO and Warner Bros., and what that means for the TV show. Enjoy!Topics/Summary:·      1:40 They need this money back. Netflix is going to invest in some big projects to make the 82.7 billion back. Harry Potter is already in production, and it will attract a huge fan base. They would be smart to keep this show in the works.·      7:24 Is the show going to change? In a dystopian media overlord world, the answer would be yes. But I think we still live in a world with some creative freedom, I don't think Netflix will step in and make any changes. I hope….·      13:53 Spinoffs! Netflix has a whole bunch of money and we can hope for more HP content on top of the TV show. Marauders? Hogwarts founders? Voldemort? Dumbledore? Dare we say: Fantastic Beasts?Having anything you want to hear or say? Click here for a voice submission or here for text. ThePotterDiscussion@gmail.comthepotterdiscussion.comNox

Steve Benson is the Founder and CEO of Badger Maps, a leading route-planning and mapping platform built specifically for field sales teams. With a background in geography, an MBA, and experience at companies like IBM, HP, and Google, Steve combined his expertise in mapping and sales strategy to help outside sales professionals work smarter, not harder. His mission is to eliminate wasted time in the field so salespeople can focus on what truly matters, building relationships and creating value for customers.SHOW SUMMARYIn this episode of the Selling from the Heart Podcast, Larry Levine and Darrell Amy are joined by Steve Benson, Founder and CEO of Badger Maps. The conversation explores how field sales professionals can dramatically improve productivity by optimizing routes, planning ahead, and eliminating inefficiencies. Steve shares practical insights on how technology can support—not replace—authentic, relationship-driven selling. This episode highlights how reclaiming wasted time allows sales professionals to spend more meaningful time with customers, deepen trust, and drive stronger results.KEY TAKEAWAYSThe Human Element: Sales is fundamentally a human interaction rooted in authenticity and trust—technology should enable, not replace, this.Leverage Efficiency Tools: Utilize efficiency tools, like route planners and virtual assistants, to handle logistical tasks, freeing the salesperson to focus exclusively on building relationships.Route Planning is Power: Optimizing routes and planning customer visits can save significant hours each week for field sales teams, directly impacting time-to-revenue.Focus on the Core: Cutting out distractions and concentrating on real customer conversations and value creation leads directly to better sales results.Repurpose Wasted Time: Regularly assess and repurpose time spent on low-value tasks (like driving or scheduling) into high-value activities, such as meeting more clients or performing account research.HIGHLIGHT QUOTESSales is as old as civilization… this is a very human interaction.If you just focus on how am I going to create value for this person… that's all sales is.It's a noisy world… people's guard is generally up, and they are generally suspicious of things.Repurpose your time… if you could repurpose three hours a day into seeing another customer, that's 15 hours a week. Something tells me you'd grow sales, build more trust, and grow client relationships a whole lot more.

Scammer Payback - What to look out for! US State Dept. changing back to original Font, Old 1978 show warns of Computer Privacy, HP Laptop charger getting warm, Rockford Files Message Machine messages! HP 9025 Inkjet printer, 5 year old Dell upgraded from Win 10 to Win 11 issues with DELL BIOS Boot,

Tony: -Carbonation Station: 3D Energy Blueberry Mist   -Smart Phones are risky for kids (duh): https://futurism.com/health-medicine/grim-happenings-kids-smartphones   -Stop me if you've heard this one before…: https://www.tomshardware.com/tech-industry/cyber-security/researcher-finds-undocumented-microphone-and-major-security-flaws-in-sipeed-nanokvm   -New Amazfit watch leaked: https://www.techradar.com/health-fitness/smartwatches/forget-the-apple-watch-se-3-it-looks-like-a-big-sequel-to-our-best-ever-cheap-fitness-watch-has-just-leaked   Jarron:  -Dell and HP disable HEVC support in their laptops for some reason: https://hardware.slashdot.org/story/25/11/21/0616243/hp-and-dell-disable-hevc-support-built-into-their-laptops-cpus?utm_source=rss0.9mainlinkanon&utm_medium=feed   -Cool gadget: https://www.theverge.com/news/838885/xteink-x4-e-reader-magnetic-apple-iphone-google-pixel   -Maybe don't buy that toilet camera.  https://arstechnica.com/gadgets/2025/12/despite-accessing-user-data-kohler-still-says-its-smart-toilet-cameras-use-e2ee/   Owen: -Australia bans social media for kids under 16. https://tech.slashdot.org/story/25/12/09/2112230/millions-of-australian-teens-lose-access-to-social-media-as-ban-takes-effect   -I would LOVE to see Monsanto get sued out of existence. https://science.slashdot.org/story/25/12/09/053254/science-journal-retracts-study-on-safety-of-monsantos-roundup   Lando: -New Smart Ring! https://techcrunch.com/2025/12/09/pebbles-founder-introduces-a-75-ai-smart-ring-for-recording-brief-notes-with-a-press-of-a-button/ 

On this Live Greatly podcast episode, Kristel Bauer sits down with "Courage Catalyst" Dr. Margie Warrell, six-time bestselling author of The Courage Gap.  Kristel and Margie discuss how to navigate being an insecure overachiever and how to build courage. Tune in now!  Key Takeaways From This Episode: A look into being an insecure overachiever and how to overcome it Tips to build courage within ourselves A look into Dr. Warrell's book, The Courage Gap ABOUT DR. MARGIE WARRELL Dr. Margie Warrell is a six-time bestselling author, leadership advisor, keynote speaker, and "courage catalyst" bringing deep insight into human and organizational behavior to foster braver leadership and better outcomes.  Dr. Warrell has gained profound insights on managing fear, navigating risk, and embracing change since her childhood in rural Australia. Thirty years of living and working around the world—from Papua, New Guinea to Singapore—have provided her with a globally grounded perspective on navigating risk and overcoming the barriers that stifle potential in individuals and organizations. Drawing on her doctoral research and experience in coaching and Fortune 500 consulting, Dr. Warrell is a trusted advisor across private and public sectors, helping to embolden braver leadership and cultivate forward-thinking "cultures of courage" that counter change resistance, foster learning, and accelerate growth. Organizations such as NASA, Dell, Morgan Stanley, SAP, Novartis, the UN Foundation, HP, Google, and Johnson & Johnson have sought her expertise.  Author of the new book, The Courage Gap, Dr. Warrell is renowned for her ability to bridge the "head and heart" as a writer and speaker. She has also co-authored two other books with Stephen Covey, Ken Blanchard, and Jack Canfield. Her interviews with leaders and luminaries—including Bill Marriott, Richard Branson, and Amy Edmondson of Harvard Business School—inform her thought leadership, which she shares through her global top 1.5% podcast, Live Brave, Forbes column, and leading media outlets such as CNN, Bloomberg, and the WSJ. Dr. Warrell's commitment to "braver leadership for a better world" extends to advising US Congressional Chiefs, McCain Global Fellows, and emerging female leaders in burgeoning democracies. A passionate advocate for women in leadership, she has served on numerous government roundtables, co-led Korn Ferry's Power of All initiative to advance more women to C-suite and board tables, and been Senior Partner in their CEO & Leadership Institute. Connect with Dr. Warrell Order Dr. Warrell's book: https://a.co/d/81cuf2F  Website: https://margiewarrell.com/  Linkedin: https://www.linkedin.com/in/margiewarrell/  Instagram: https://www.instagram.com/margiewarrell/  About the Host of the Live Greatly podcast, Kristel Bauer: Kristel Bauer is a corporate wellness and performance expert, keynote speaker and TEDx speaker supporting organizations and individuals on their journeys for more happiness and success. She is the author of Work-Life Tango: Finding Happiness, Harmony, and Peak Performance Wherever You Work (John Murray Business November 19, 2024). With Kristel's healthcare background, she provides data driven actionable strategies to leverage happiness and high-power habits to drive growth mindsets, peak performance, profitability, well-being and a culture of excellence. Kristel's keynotes provide insights to "Live Greatly" while promoting leadership development and team building.   Kristel is the creator and host of her global top self-improvement podcast, Live Greatly. She is a contributing writer for Entrepreneur, and she is an influencer in the business and wellness space having been recognized as a Top 10 Social Media Influencer of 2021 in Forbes. As an Integrative Medicine Fellow & Physician Assistant having practiced clinically in Integrative Psychiatry, Kristel has a unique perspective into attaining a mindset for more happiness and success. Kristel has presented to groups from the American Gas Association, Bank of America, bp, Commercial Metals Company, General Mills, Northwestern University, Santander Bank and many more. Kristel has been featured in Forbes, Forest & Bluff Magazine, Authority Magazine & Podcast Magazine and she has appeared on ABC 7 Chicago, WGN Daytime Chicago, Fox 4's WDAF-TV's Great Day KC, and Ticker News. Kristel lives in the Fort Lauderdale, Florida area and she can be booked for speaking engagements worldwide. To Book Kristel as a speaker for your next event, click here. Website: www.livegreatly.co  Follow Kristel Bauer on: Instagram: @livegreatly_co  LinkedIn: Kristel Bauer Twitter: @livegreatly_co Facebook: @livegreatly.co Youtube: Live Greatly, Kristel Bauer To Watch Kristel Bauer's TEDx talk of Redefining Work/Life Balance in a COVID-19 World click here. Click HERE to check out Kristel's corporate wellness and leadership blog Click HERE to check out Kristel's Travel and Wellness Blog Disclaimer: The contents of this podcast are intended for informational and educational purposes only. Always seek the guidance of your physician for any recommendations specific to you or for any questions regarding your specific health, your sleep patterns changes to diet and exercise, or any medical conditions.  Always consult your physician before starting any supplements or new lifestyle programs. All information, views and statements shared on the Live Greatly podcast are purely the opinions of the authors, and are not medical advice or treatment recommendations.  They have not been evaluated by the food and drug administration.  Opinions of guests are their own and Kristel Bauer & this podcast does not endorse or accept responsibility for statements made by guests.  Neither Kristel Bauer nor this podcast takes responsibility for possible health consequences of a person or persons following the information in this educational content.  Always consult your physician for recommendations specific to you.

After surviving Thanksgiving and the subsequent biting cold, we jumped into the FOLLOW UP with news that Malaysia is joining the trend by taking steps to ban social media for children under 16, mirroring similar actions in Australia and Denmark—it seems the world is finally realizing the internet is a toxic wasteland for the kids. We also discussed Apple's photo AI, which is apparently still in beta, if the results are anything to go by. The bulk of our discussion centered on the spectacular, flaming death of the Department of Government Efficiency (DOGE), which is Officially Dead. We broke down a brief rundown of the damages this vanity project caused, from humanitarian disasters overseas to administrative chaos and the loss of hundreds of thousands of jobs domestically, proving the "savings" were pure illusion. Now, with the collapse, the 'Suddenly exposed' DOGE employees fear prosecution after Musk abandoned them, learning the hard way that billionaire guardianship has an expiration date.The job market is just great, with both Apple laying off part of its sales team despite record revenue, and HP joining the List of Tech Companies Cutting Jobs and pointing to AI as the convenient scapegoat for laying off 10% of their workforce. Meanwhile, we found out the most popular social media platform among US adults isn't Instagram or TikTok—it's YouTube—while Meta allegedly buried research showing its products are harming users, confirming what we've known all along: they're evil, but they already got your grandma hooked. Adding to the misery, An Alarming Number of Teens Say They Turn To AI For Company, Study Finds, because why talk to a real, messy human when a bot can gaslight you more efficiently? Sam Altman's financial troubles are spilling over, with Sam Altman's Business Buddies Are Getting Stung (sorry, SoftBank and Oracle), and analysts estimate OpenAI Is Just $200 Billion Away From Still Losing Money, HSBC Says, a comical hole they plan to fill by asking for more free money. Legally, OpenAI can't use the Word ‘Cameo' in Sora now, thanks to a trademark suit, and Warner Music is playing both sides by dropping its lawsuit against Suno in exchange for a licensing agreement. Finally, in some truly dark news, a Marc Andreessen-backed Super-PAC Pours Millions Into Fighting State AI Regulations, and X's new location feature reveals that New X Feature Reveals Many MAGA Patriots on X Are Not Even Based in the U.S.After ranting about my misery dealing with the Open Dialogue bug in a beta build and declaring my return to "pedestrian releases," we got into APPS & DOODADS. Spotify is actually doing something cool with its new SongDNA feature, which shows you who sampled what (and they bought WhoSampled to do it). They're also testing Spotify's New AI-powered audiobook Recaps to remind you where you left off—Amazon is doing the same with AI-powered series Recap Videos for Prime Video. Amazon is also rolling out Alexa Home Theater surround sound for Echo speakers, making those budget speakers slightly more useful. We ran through some great stocking stuffers in Jason's Holiday Gift Guide, including Velcro cable ties and the Contigo travel mug, before moving on to MEDIA CANDY, which included Dan Carlin's Common Sense, Nathan Fillion and Alan Tudyk's new podcast Once We Were Spacemen, and a discussion on why Stranger Things Lost the Plot. We then got deeply uncomfortable talking about a Toronto ASMR spa that offers doctor roleplay, and closed out by talking about the documentary Quiet Please… about the neurological disorder misophonia. The episode finished with the AT THE LIBRARY segment, covering the Milli Vanilli memoir You Know It's True and the sci-fi short story collection The Time Travelers Passport.Show notes at https://gog.show/724Watch now on YouTube: https://youtu.be/PoMa9FM5QEE?si=4r25yqv_0u8aXHF7Sponsors:MasterClass - Get up to 50% off at MASTERCLASS.com/GRUMPYOLDGEEKSGusto - Try Gusto today at gusto.com/grumpy, and get three months free when you run your first payroll.Private Internet Access - Go to GOG.Show/vpn and sign up today. For a limited time only, you can get OUR favorite VPN for as little as $2.03 a month.SetApp - With a single monthly subscription you get 240+ apps for your Mac. Go to SetApp and get started today!!!1Password - Get a great deal on the only password manager recommended by Grumpy Old Geeks! gog.show/1passwordFOLLOW UPMalaysia takes steps to ban social media for children under 16IN THE NEWSDOGE Is Officially Dead'Suddenly exposed' DOGE employees fear prosecution after Musk abandoned them: reportApple lays off part of its sales teamHP Joins List of Tech Companies Cutting Jobs and Pointing to AIThe most popular social media platform among US adults isn't Instagram or TikTokMeta allegedly buried research showing its products are harming usersAn Alarming Number of Teens Say They Turn To AI For Company, Study FindsSam Altman's Business Buddies Are Getting StungOpenAI Is Just $200 Billion Away From Still Losing Money, HSBC SaysOpenAI Can't Legally Use the Word ‘Cameo' in Sora NowWarner Music drops lawsuit against AI music platform Suno in exchange for licensing agreementMarc Andreessen-Backed Super-PAC Pours Millions Into Fighting State AI RegulationsNew X Feature Reveals Many MAGA Patriots on X Are Not Even Based in The U.S.MEDIA CANDYCommon Sense 325 – Who's the Boss?Once We Were SpacemenHow Stranger Things Lost the PlotBeing EddieThe Beast in MeThe RosesAt Toronto's new ASMR spa, sensory stimulation slips out of the internet and into real lifeQuiet Please…APPS & DOODADSSpotify's SongDNA feature will show you which songs are sampled on a trackMaking of "The Prodigy - Smack My Bitch Up" in Ableton by Jim PavloffSpotify's New AI-Powered Audiobook Recaps Will Remind You Where You Left OffAmazon Launches AI-Powered Series Recap VideosAlexa Home Theater surround sound for Echo speakers is rolling out nowDashaun No Sadè - Episode 13 Durand BernarrGuermok Video Capture Card, 4K USB3.0 HDMI to USB C Capture Card for Streaming, 1080P 60FPS, Compatible with iPad Mac OS Windows, Quest 3, OBS, PS5/4, Switch2/1, Xbox, Camera (Silver)Meike 35mm F2.0 Auto Focus Full Frame STM Stepping Motor Lens Compatible with Nikon Z Mount CamerasOBS StudioRogue Amoeba LoopbackScientists Reveal What Black Friday Is Doing to Your BrainVELCRO Brand 150pk Cable Ties Value Pack, 8in | Stocking Stuffer Gifts for Tech Lovers | For Wire Management and Cord Organizer | Replace Zip Ties with Reusable Straps, Reduce WasteHand Holder Strap for ipad, Tablet Hand Holder Strap, Universal Handle Grip for iPad Kindle, Mini Tablets and Cases (Black)Anker USB C Hub, 7-in-1 Multi-Port USB Adapter for Laptops, 4K@60Hz USB C to HDMI Splitter, 85W Max Power Delivery, 3xUSBA & C 3.0 Data Ports, SD/TF Card, for Type C DevicesContigo AUTOSEAL West Loop Vacuum-Insulated Stainless Steel Travel Mug with Easy-Clean Lid 20 ozScotty Peeler Label and Sticker Remover - Single Metal Peeler -SP2Slipdrive - Portable Hard Drive Sleeve for Laptop - HDD Hard Disk Drive - Reusable Adhesive - 5.5” x 4.5” Stick on External Hard Drive Carrying Case - Travel Pocket Pouch (Large, Black)Slipdrive - Portable Hard Drive Sleeve for Laptop - SSD Solid State Drive - Reusable Adhesive - Stick on External Hard Drive Carrying Case - Pocket Pouch (Small, Black)Carlashes 1001UB Classic BlackAT THE LIBRARYYou Know It's True - The Real Story of Milli VanilliThe Time Travelers PassportThe Courage to Be Disliked: How to Free Yourself, Change Your Life, and Achieve Real Happiness by Ichiro Kishimi, Fumitake KogaSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.